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Search of human proteins with 7656922
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7656922 chromatin modifying protein 2A [Homo sapiens]
(222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38372933 chromatin modifying protein 2A [Homo sapiens] 419 e-118
gi|7656922 chromatin modifying protein 2A [Homo sapiens] 419 e-118
gi|40254866 chromatin modifying protein 2B [Homo sapiens] 130 1e-30
gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens] 94 1e-19
gi|31542306 chromatin modifying protein 1B [Homo sapiens] 92 4e-19
gi|103485496 chromatin modifying protein 1A isoform 2 [Homo sapi... 82 5e-16
gi|189409150 chromatin modifying protein 5 [Homo sapiens] 54 1e-07
gi|54144646 vacuolar protein sorting 24 isoform 2 [Homo sapiens] 54 1e-07
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 48 8e-06
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 44 1e-04
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 42 5e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 38 0.006
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 38 0.006
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 38 0.006
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 38 0.006
gi|62243374 MAD1-like 1 protein [Homo sapiens] 38 0.006
gi|62243369 MAD1-like 1 protein [Homo sapiens] 38 0.006
gi|62243332 MAD1-like 1 protein [Homo sapiens] 38 0.006
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 38 0.008
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 38 0.008
gi|221219020 NYD-SP11 protein [Homo sapiens] 37 0.018
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 37 0.018
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 37 0.018
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 35 0.039
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom... 35 0.039
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 35 0.039
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 35 0.051
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] 35 0.067
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 34 0.087
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 34 0.087
>gi|38372933 chromatin modifying protein 2A [Homo sapiens]
Length = 222
Score = 419 bits (1078), Expect = e-118
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR 60
MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR
Sbjct: 1 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR 60
Query: 61 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP 120
IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP
Sbjct: 61 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP 120
Query: 121 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS 180
QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS
Sbjct: 121 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS 180
Query: 181 NLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD 222
NLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
Sbjct: 181 NLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD 222
>gi|7656922 chromatin modifying protein 2A [Homo sapiens]
Length = 222
Score = 419 bits (1078), Expect = e-118
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR 60
MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR
Sbjct: 1 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR 60
Query: 61 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP 120
IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP
Sbjct: 61 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP 120
Query: 121 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS 180
QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS
Sbjct: 121 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS 180
Query: 181 NLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD 222
NLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
Sbjct: 181 NLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD 222
>gi|40254866 chromatin modifying protein 2B [Homo sapiens]
Length = 213
Score = 130 bits (326), Expect = 1e-30
Identities = 69/216 (31%), Positives = 123/216 (56%), Gaps = 8/216 (3%)
Query: 7 RRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDL 66
++KT ++++++ R L R + R+R LE QEK++ +IKKMAK G +A +++AK L
Sbjct: 6 KKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQL 65
Query: 67 VRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIM 126
V R+ + + + + ++S + + + S MA AM K M +N+++ + + M
Sbjct: 66 VHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTM 125
Query: 127 MEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTG 186
F+++ M+M EEM+ND +DD +DEEES +V+QVLDE+G+ ++ +++ PS
Sbjct: 126 QNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAA 185
Query: 187 GSLSVAAGGKKAEAAASALADADADLEERLKNLRRD 222
SL A+ S +D ++E +LK L D
Sbjct: 186 RSL--------PSASTSKATISDEEIERQLKALGVD 213
>gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens]
Length = 222
Score = 93.6 bits (231), Expect = 1e-19
Identities = 58/219 (26%), Positives = 116/219 (52%), Gaps = 11/219 (5%)
Query: 4 LFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRI 61
LFG+ K P+EL+ + + + MR +DR+ + ++ +E+K+ +K AK+GQ D +
Sbjct: 3 LFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIV 62
Query: 62 MAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQ 121
+AK+++R+R+ V K +A++ +V + ++ + +A +++ T+ M M +K+P+
Sbjct: 63 LAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPE 122
Query: 122 IQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGL-------- 173
IQ M E ++ + EEM+ D + EE EEE++ + ++L E+
Sbjct: 123 IQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKAPS 182
Query: 174 SLTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADL 212
+TD L P G+++ + ++ E A A+ A L
Sbjct: 183 KVTDALPE-PEPPGAMAASEDEEEEEEALEAMQSRLATL 220
>gi|31542306 chromatin modifying protein 1B [Homo sapiens]
Length = 199
Score = 92.0 bits (227), Expect = 4e-19
Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 13/199 (6%)
Query: 22 LNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRA 81
L A +EL R +K + +EK A IKK ++G M+ RI A++ +R + F+ M A
Sbjct: 11 LKFAAKELSRSAKKCDKEEKAEKAKIKKAIQKGNMEVARIHAENAIRQKNQAVNFLRMSA 70
Query: 82 NIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEE 141
+ AV+ ++QT + + ++M GV K+M + + L +I +M +FE Q E +D++ +
Sbjct: 71 RVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKTMNLEKISALMDKFEHQFETLDVQTQ 130
Query: 142 MMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAA 201
M D + + + D ++ ++ DE GL L EL G+
Sbjct: 131 QMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQ-------------GQTGSVG 177
Query: 202 ASALADADADLEERLKNLR 220
S + +L +RL LR
Sbjct: 178 TSVASAEQDELSQRLARLR 196
>gi|103485496 chromatin modifying protein 1A isoform 2 [Homo
sapiens]
Length = 196
Score = 81.6 bits (200), Expect = 5e-16
Identities = 44/180 (24%), Positives = 94/180 (52%)
Query: 27 RELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAV 86
++L++ +K E K A +KK Q ++ R+ A++ +R + ++ M + + AV
Sbjct: 13 KQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKNEGVNWLRMASRVDAV 72
Query: 87 SLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDA 146
+ K+QT + + + M VTKA+ + L ++ +M FE+Q + +D+ +M D+
Sbjct: 73 ASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDS 132
Query: 147 IDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASALA 206
+ A +E+ D+++ Q+ +E GL + D+LS LP ++ ++ + + + LA
Sbjct: 133 MSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVRSQEDQLSRRLA 192
>gi|189409150 chromatin modifying protein 5 [Homo sapiens]
Length = 219
Score = 53.9 bits (128), Expect = 1e-07
Identities = 46/191 (24%), Positives = 88/191 (46%), Gaps = 7/191 (3%)
Query: 1 MDLLFGRRK--TPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA 58
M+ LFG+ K P L ++ +D++ +L+ + K IKKM + +
Sbjct: 1 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
Query: 59 VRIMAKDLVRTRRYVRK----FVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMN 114
V+ A +++ +R + N++ + IQ+LK + AMK K M
Sbjct: 61 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120
Query: 115 RQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEED-EEESDAVVSQVLDELGL 173
+Q+K+ QI+ + + E E + +E ++ + DE+D E E DA+ ++L +
Sbjct: 121 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS 180
Query: 174 SLTDELSNLPS 184
S DE ++ P+
Sbjct: 181 SYLDEAASAPA 191
>gi|54144646 vacuolar protein sorting 24 isoform 2 [Homo sapiens]
Length = 156
Score = 53.9 bits (128), Expect = 1e-07
Identities = 37/155 (23%), Positives = 76/155 (49%), Gaps = 9/155 (5%)
Query: 66 LVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKI 125
++R+R+ V K +A++ +V + ++ + +A +++ T+ M M +K+P+IQ
Sbjct: 1 MIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQAT 60
Query: 126 MMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGL--------SLTD 177
M E ++ + EEM+ D + EE EEE++ + ++L E+ +TD
Sbjct: 61 MRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKAPSKVTD 120
Query: 178 ELSNLPSTGGSLSVAAGGKKAEAAASALADADADL 212
L P G+++ + ++ E A A+ A L
Sbjct: 121 ALPE-PEPPGAMAASEDEEEEEEALEAMQSRLATL 154
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 47.8 bits (112), Expect = 8e-06
Identities = 37/187 (19%), Positives = 96/187 (51%), Gaps = 19/187 (10%)
Query: 7 RRKTPEELLRQNQRALNRAM-RELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKD 65
R + E LL Q ++AL +++ +E +R ++ LE ++ ++ +++A+Q + ++
Sbjct: 711 RMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQKE-----VLESS 765
Query: 66 LVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVT------KAMGTMNRQLKL 119
+ +R ++ +++ K+Q L+++ + + + KA M ++ K
Sbjct: 766 IAHEKRKAKEA------LESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKK 819
Query: 120 PQ-IQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDE 178
Q ++ + + + + E+ + KE+++N+ + DA+ E+ +++ A S + L L L +
Sbjct: 820 VQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNET 879
Query: 179 LSNLPST 185
L+ L +T
Sbjct: 880 LAELETT 886
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 43.9 bits (102), Expect = 1e-04
Identities = 54/235 (22%), Positives = 102/235 (43%), Gaps = 39/235 (16%)
Query: 13 ELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQ--------GQMDAVR-IMA 63
E LRQ + L A EL R+R +LE +++ + D ++ ++ Q++ R ++A
Sbjct: 620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 679
Query: 64 KDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKA-MGTMNRQLKLPQI 122
K+LV R + + L R +QA A+ + +TKA G + +L + ++
Sbjct: 680 KELVEVREALSRATLQRDMLQA------------EKAEVAEALTKAEAGRVELELSMTKL 727
Query: 123 QKIMMEFERQ-AEIMDMKEEMMNDAID------------DAMGDEEDEEESDAVVSQVLD 169
+ + +++ + E + D +D A+ + + E +A V++
Sbjct: 728 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 787
Query: 170 EL--GLSLTDELSNLPSTGGSLSVAAGGKKA-EAAASALADADADLEERLKNLRR 221
E L L E++ GSL VA ++A E L + L+E+L L R
Sbjct: 788 ERLEELRLEQEVAR-QGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Score = 28.1 bits (61), Expect = 6.2
Identities = 31/174 (17%), Positives = 77/174 (44%), Gaps = 13/174 (7%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRR 71
EE +R+++R + ++ + L+ E ++ A +K++K ++ L +R
Sbjct: 1585 EESVRRSERERRATLDQVATLERSLQATESELRASQEKISK------MKANETKLEGDKR 1638
Query: 72 YVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFER 131
+++ VL + + V L++Q + ++ G++ +R+ + +Q + +R
Sbjct: 1639 RLKE-VLDASESRTVKLELQRRSLEGELQRSRLGLS------DREAQAQALQDRVDSLQR 1691
Query: 132 QAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPST 185
Q ++K + ++ G EES+ + + L +L ++L ST
Sbjct: 1692 QVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNST 1745
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 21/164 (12%)
Query: 9 KTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVR 68
K EEL + R N +E + +EK + D KK KQ Q
Sbjct: 1219 KLKEELSASSARTQNLKADLQRKEEDYADLKEK--LTDAKKQIKQVQ------------- 1263
Query: 69 TRRYVRKFVLMRANIQAVSLKIQTL-KSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMM 127
++ +MR + + +KI L K N +Q + + + + QL ++++ +
Sbjct: 1264 -----KEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQ 1318
Query: 128 EFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDEL 171
++ER + +++KE+++ D E+ + E D V+ L+E+
Sbjct: 1319 QYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEV 1362
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 38.1 bits (87), Expect = 0.006
Identities = 50/236 (21%), Positives = 101/236 (42%), Gaps = 36/236 (15%)
Query: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQK---LETQEKKIIADIKKM------AKQG 54
L R + EE RQ QR L+ EL+ ER++ +KK+ D+K + A +G
Sbjct: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639
Query: 55 QMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMN 114
+ +A++ + K + + + R+ RA+ + T K N A+++
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKENEKKAKSL----------- 1685
Query: 115 RQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLS 174
+ L Q+Q+ + ER + D+++E + + + ++ ++ + + +L
Sbjct: 1686 -EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
Query: 175 LTDELSNLPSTGGSLSVAAGGKKAEAAASALA----------DADADLEERLKNLR 220
L +E N+ + + A ++AE ++ LA A LE + K LR
Sbjct: 1745 LEEEQGNMEAMSDRVRKAT--QQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
Score = 35.0 bits (79), Expect = 0.051
Identities = 40/198 (20%), Positives = 81/198 (40%), Gaps = 20/198 (10%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADI------------KKMAKQGQMDAV 59
EEL Q ++ RA LD+ +Q LE + + ++ KK + Q+ +
Sbjct: 1206 EELTEQLEQ-FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 60 RIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKL 119
+ D R R + V N ++ T N + +A+K + K + +++ QL+
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQN----EVESVTGMLNEAEGKAIK-LAKDVASLSSQLQ- 1318
Query: 120 PQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDEL 179
Q+++ E RQ + K + + + ++E E+ + + + L + L+D
Sbjct: 1319 -DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1377
Query: 180 SNLPSTGGSLSVAAGGKK 197
L ++ GKK
Sbjct: 1378 KKLQDFASTVEALEEGKK 1395
Score = 31.6 bits (70), Expect = 0.56
Identities = 50/242 (20%), Positives = 93/242 (38%), Gaps = 43/242 (17%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKK------IIADIKKMAKQGQMDAVRIMAKD 65
E+ + Q+ L+ + +LD +RQ + EKK ++A+ K ++ + + R A+
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE- 1477
Query: 66 LVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKI 125
+ + L RA +A+ K + ++N + M+ + + + + + +++K
Sbjct: 1478 --AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH--ELEKS 1533
Query: 126 MMEFERQAEIMDMKEEMMNDAID----------------------DAMGDEEDEEESDAV 163
E Q E M + E + D + D +E EE
Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 1593
Query: 164 VSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASAL-ADADADL---EERLKNL 219
+ + L E L DE AA KK E L AD+ + EE +K L
Sbjct: 1594 LQRQLHEYETELEDERKQ------RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1647
Query: 220 RR 221
R+
Sbjct: 1648 RK 1649
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 38.1 bits (87), Expect = 0.006
Identities = 50/236 (21%), Positives = 101/236 (42%), Gaps = 36/236 (15%)
Query: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQK---LETQEKKIIADIKKM------AKQG 54
L R + EE RQ QR L+ EL+ ER++ +KK+ D+K + A +G
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646
Query: 55 QMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMN 114
+ +A++ + K + + + R+ RA+ + T K N A+++
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKENEKKAKSL----------- 1692
Query: 115 RQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLS 174
+ L Q+Q+ + ER + D+++E + + + ++ ++ + + +L
Sbjct: 1693 -EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
Query: 175 LTDELSNLPSTGGSLSVAAGGKKAEAAASALA----------DADADLEERLKNLR 220
L +E N+ + + A ++AE ++ LA A LE + K LR
Sbjct: 1752 LEEEQGNMEAMSDRVRKAT--QQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805
Score = 35.0 bits (79), Expect = 0.051
Identities = 40/198 (20%), Positives = 81/198 (40%), Gaps = 20/198 (10%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADI------------KKMAKQGQMDAV 59
EEL Q ++ RA LD+ +Q LE + + ++ KK + Q+ +
Sbjct: 1213 EELTEQLEQ-FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 60 RIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKL 119
+ D R R + V N ++ T N + +A+K + K + +++ QL+
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQN----EVESVTGMLNEAEGKAIK-LAKDVASLSSQLQ- 1325
Query: 120 PQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDEL 179
Q+++ E RQ + K + + + ++E E+ + + + L + L+D
Sbjct: 1326 -DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1384
Query: 180 SNLPSTGGSLSVAAGGKK 197
L ++ GKK
Sbjct: 1385 KKLQDFASTVEALEEGKK 1402
Score = 31.6 bits (70), Expect = 0.56
Identities = 50/242 (20%), Positives = 93/242 (38%), Gaps = 43/242 (17%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKK------IIADIKKMAKQGQMDAVRIMAKD 65
E+ + Q+ L+ + +LD +RQ + EKK ++A+ K ++ + + R A+
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE- 1484
Query: 66 LVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKI 125
+ + L RA +A+ K + ++N + M+ + + + + + +++K
Sbjct: 1485 --AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH--ELEKS 1540
Query: 126 MMEFERQAEIMDMKEEMMNDAID----------------------DAMGDEEDEEESDAV 163
E Q E M + E + D + D +E EE
Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 1600
Query: 164 VSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASAL-ADADADL---EERLKNL 219
+ + L E L DE AA KK E L AD+ + EE +K L
Sbjct: 1601 LQRQLHEYETELEDERKQ------RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1654
Query: 220 RR 221
R+
Sbjct: 1655 RK 1656
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 38.1 bits (87), Expect = 0.006
Identities = 50/236 (21%), Positives = 101/236 (42%), Gaps = 36/236 (15%)
Query: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQK---LETQEKKIIADIKKM------AKQG 54
L R + EE RQ QR L+ EL+ ER++ +KK+ D+K + A +G
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646
Query: 55 QMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMN 114
+ +A++ + K + + + R+ RA+ + T K N A+++
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKENEKKAKSL----------- 1692
Query: 115 RQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLS 174
+ L Q+Q+ + ER + D+++E + + + ++ ++ + + +L
Sbjct: 1693 -EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
Query: 175 LTDELSNLPSTGGSLSVAAGGKKAEAAASALA----------DADADLEERLKNLR 220
L +E N+ + + A ++AE ++ LA A LE + K LR
Sbjct: 1752 LEEEQGNMEAMSDRVRKAT--QQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805
Score = 35.0 bits (79), Expect = 0.051
Identities = 40/198 (20%), Positives = 81/198 (40%), Gaps = 20/198 (10%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADI------------KKMAKQGQMDAV 59
EEL Q ++ RA LD+ +Q LE + + ++ KK + Q+ +
Sbjct: 1213 EELTEQLEQ-FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 60 RIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKL 119
+ D R R + V N ++ T N + +A+K + K + +++ QL+
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQN----EVESVTGMLNEAEGKAIK-LAKDVASLSSQLQ- 1325
Query: 120 PQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDEL 179
Q+++ E RQ + K + + + ++E E+ + + + L + L+D
Sbjct: 1326 -DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1384
Query: 180 SNLPSTGGSLSVAAGGKK 197
L ++ GKK
Sbjct: 1385 KKLQDFASTVEALEEGKK 1402
Score = 31.6 bits (70), Expect = 0.56
Identities = 50/242 (20%), Positives = 93/242 (38%), Gaps = 43/242 (17%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKK------IIADIKKMAKQGQMDAVRIMAKD 65
E+ + Q+ L+ + +LD +RQ + EKK ++A+ K ++ + + R A+
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE- 1484
Query: 66 LVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKI 125
+ + L RA +A+ K + ++N + M+ + + + + + +++K
Sbjct: 1485 --AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH--ELEKS 1540
Query: 126 MMEFERQAEIMDMKEEMMNDAID----------------------DAMGDEEDEEESDAV 163
E Q E M + E + D + D +E EE
Sbjct: 1541 KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 1600
Query: 164 VSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASAL-ADADADL---EERLKNL 219
+ + L E L DE AA KK E L AD+ + EE +K L
Sbjct: 1601 LQRQLHEYETELEDERKQ------RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1654
Query: 220 RR 221
R+
Sbjct: 1655 RK 1656
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 38.1 bits (87), Expect = 0.006
Identities = 50/236 (21%), Positives = 101/236 (42%), Gaps = 36/236 (15%)
Query: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQK---LETQEKKIIADIKKM------AKQG 54
L R + EE RQ QR L+ EL+ ER++ +KK+ D+K + A +G
Sbjct: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639
Query: 55 QMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMN 114
+ +A++ + K + + + R+ RA+ + T K N A+++
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKENEKKAKSL----------- 1685
Query: 115 RQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLS 174
+ L Q+Q+ + ER + D+++E + + + ++ ++ + + +L
Sbjct: 1686 -EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
Query: 175 LTDELSNLPSTGGSLSVAAGGKKAEAAASALA----------DADADLEERLKNLR 220
L +E N+ + + A ++AE ++ LA A LE + K LR
Sbjct: 1745 LEEEQGNMEAMSDRVRKAT--QQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
Score = 35.0 bits (79), Expect = 0.051
Identities = 40/198 (20%), Positives = 81/198 (40%), Gaps = 20/198 (10%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADI------------KKMAKQGQMDAV 59
EEL Q ++ RA LD+ +Q LE + + ++ KK + Q+ +
Sbjct: 1206 EELTEQLEQ-FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 60 RIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKL 119
+ D R R + V N ++ T N + +A+K + K + +++ QL+
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQN----EVESVTGMLNEAEGKAIK-LAKDVASLSSQLQ- 1318
Query: 120 PQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDEL 179
Q+++ E RQ + K + + + ++E E+ + + + L + L+D
Sbjct: 1319 -DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1377
Query: 180 SNLPSTGGSLSVAAGGKK 197
L ++ GKK
Sbjct: 1378 KKLQDFASTVEALEEGKK 1395
Score = 31.6 bits (70), Expect = 0.56
Identities = 50/242 (20%), Positives = 93/242 (38%), Gaps = 43/242 (17%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKK------IIADIKKMAKQGQMDAVRIMAKD 65
E+ + Q+ L+ + +LD +RQ + EKK ++A+ K ++ + + R A+
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE- 1477
Query: 66 LVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKI 125
+ + L RA +A+ K + ++N + M+ + + + + + +++K
Sbjct: 1478 --AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH--ELEKS 1533
Query: 126 MMEFERQAEIMDMKEEMMNDAID----------------------DAMGDEEDEEESDAV 163
E Q E M + E + D + D +E EE
Sbjct: 1534 KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 1593
Query: 164 VSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASAL-ADADADL---EERLKNL 219
+ + L E L DE AA KK E L AD+ + EE +K L
Sbjct: 1594 LQRQLHEYETELEDERKQ------RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1647
Query: 220 RR 221
R+
Sbjct: 1648 RK 1649
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 38.1 bits (87), Expect = 0.006
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 28/142 (19%)
Query: 16 RQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRK 75
R+ L + EL+ ER +LE +++ + A +++ A QG D R
Sbjct: 495 REEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTK------------- 541
Query: 76 FVLMRANIQAVSLKIQTLKSNNSMAQA----MKGVTKAM---GTMNRQLK-----LPQIQ 123
++ ++ S+ Q L+ ++S QA ++G+ +AM GT+ L+ LP
Sbjct: 542 --VLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPS-S 598
Query: 124 KIMMEFERQAEIMDMKEEMMND 145
K + E ++Q E ++K + + +
Sbjct: 599 KEVAELKKQVESAELKNQRLKE 620
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 38.1 bits (87), Expect = 0.006
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 28/142 (19%)
Query: 16 RQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRK 75
R+ L + EL+ ER +LE +++ + A +++ A QG D R
Sbjct: 495 REEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTK------------- 541
Query: 76 FVLMRANIQAVSLKIQTLKSNNSMAQA----MKGVTKAM---GTMNRQLK-----LPQIQ 123
++ ++ S+ Q L+ ++S QA ++G+ +AM GT+ L+ LP
Sbjct: 542 --VLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPS-S 598
Query: 124 KIMMEFERQAEIMDMKEEMMND 145
K + E ++Q E ++K + + +
Sbjct: 599 KEVAELKKQVESAELKNQRLKE 620
>gi|62243332 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 38.1 bits (87), Expect = 0.006
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 28/142 (19%)
Query: 16 RQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRK 75
R+ L + EL+ ER +LE +++ + A +++ A QG D R
Sbjct: 495 REEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTK------------- 541
Query: 76 FVLMRANIQAVSLKIQTLKSNNSMAQA----MKGVTKAM---GTMNRQLK-----LPQIQ 123
++ ++ S+ Q L+ ++S QA ++G+ +AM GT+ L+ LP
Sbjct: 542 --VLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPS-S 598
Query: 124 KIMMEFERQAEIMDMKEEMMND 145
K + E ++Q E ++K + + +
Sbjct: 599 KEVAELKKQVESAELKNQRLKE 620
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 37.7 bits (86), Expect = 0.008
Identities = 45/211 (21%), Positives = 87/211 (41%), Gaps = 12/211 (5%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADIK--KMAKQGQMDAVRIMAKDLVRT 69
EEL Q ++A R L++ +Q LET K++ ++K + K + + +
Sbjct: 1206 EELSEQLEQA-KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 70 RRYVRKFVLMRANIQAVSLKIQTLKSNNSMA---QAMKGVTKAMGTMNRQLKLPQIQKIM 126
V + +R + + K+Q N S KG+ A + + +L Q+++
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL 1324
Query: 127 MEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTG 186
E RQ + + + + + +E+EEE+ + + + L L D +
Sbjct: 1325 QEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDL 1384
Query: 187 GSLSVAAGGKKAEAAASALADADADLEERLK 217
G++ EA L DA+A L +RL+
Sbjct: 1385 GTIE-----SLEEAKKKLLKDAEA-LSQRLE 1409
Score = 32.3 bits (72), Expect = 0.33
Identities = 36/171 (21%), Positives = 79/171 (46%), Gaps = 9/171 (5%)
Query: 15 LRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVR 74
L ++ AL++ + E KLE + ++ ++ + +D R +A +L + ++
Sbjct: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVD--LDHQRQVASNLEKKQK--- 1451
Query: 75 KFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAE 134
KF + A +++S + + + + A+A + TKA+ L + + EFERQ +
Sbjct: 1452 KFDQLLAEEKSISARYAE-ERDRAEAEAREKETKALSLARA---LEEALEAKEEFERQNK 1507
Query: 135 IMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPST 185
+ E + + DD + + E+S + Q ++E+ L + L +T
Sbjct: 1508 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Score = 30.8 bits (68), Expect = 0.96
Identities = 40/227 (17%), Positives = 100/227 (44%), Gaps = 21/227 (9%)
Query: 12 EELLR--QNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRT 69
EELL+ + Q + + E++R+ Q+L +EK I+A+ + + +A + A+ +
Sbjct: 859 EELLKVKEKQTKVEGELEEMERKHQQL-LEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
Query: 70 RRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAM-----------KGVTKAMGT--MNRQ 116
+ + + ++ + Q L++ QA +G + + + +
Sbjct: 918 QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977
Query: 117 LKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLT 176
K+ ++++ ++ E Q ++++M D I + +EEE ++++ ++ + ++
Sbjct: 978 AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037
Query: 177 D---ELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLR 220
D L T L A +K + + L D A+L+ ++ L+
Sbjct: 1038 DLEERLKKEEKTRQELEKAK--RKLDGETTDLQDQIAELQAQIDELK 1082
Score = 28.5 bits (62), Expect = 4.8
Identities = 33/180 (18%), Positives = 84/180 (46%), Gaps = 14/180 (7%)
Query: 9 KTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVR 68
+T +E + +R L + +REL+ E + Q +A KKM + +I A + R
Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR 1640
Query: 69 TRRYVRKFVLMRANIQAVSLKIQTLKSNNS--MAQAMKGVTKAMGTMNRQLKLPQIQKIM 126
+++ ++A ++ +++ +++ AQ+ + K + + ++ Q+Q+ +
Sbjct: 1641 D-EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKK---LKSLEAEILQLQEEL 1696
Query: 127 MEFERQAEIMDMKEEMMNDAIDDAMGDE----EDEEESDAVVSQVLDELGLSLTDELSNL 182
ER + + + + D I ++ + +++ +A ++Q+ +E L +E SN+
Sbjct: 1697 ASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEE----LEEEQSNM 1752
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 37.7 bits (86), Expect = 0.008
Identities = 37/182 (20%), Positives = 80/182 (43%), Gaps = 17/182 (9%)
Query: 7 RRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDL 66
R K EE R +R + + EL+RER++ E K+ + ++ Q ++ A++
Sbjct: 291 REKEAEERQRAEERK-QKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQ 349
Query: 67 VRTRRYV----RKFVLMRANIQAVSLKIQTLKSNNSM-----AQAMKGVTKAMGTMNRQL 117
+ + + RK +L + N+Q++ L + L ++ Q + + R+L
Sbjct: 350 KQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRL 409
Query: 118 KLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTD 177
+ +++++ E ER + + E+ + + + D+ S DELG++ D
Sbjct: 410 QEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDD-------SHTHDELGVAHAD 462
Query: 178 EL 179
L
Sbjct: 463 LL 464
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 36.6 bits (83), Expect = 0.018
Identities = 18/64 (28%), Positives = 37/64 (57%)
Query: 104 KGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAV 163
+G K + + K + +K E + + E+ + KEE+M++ +++ DEE+EEES ++
Sbjct: 2274 EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSL 2333
Query: 164 VSQV 167
+V
Sbjct: 2334 EEEV 2337
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/49 (30%), Positives = 29/49 (59%)
Query: 6 GRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQG 54
G+ EE L Q L++ +L ++R+KL + +K+ + +K+AK+G
Sbjct: 1635 GKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKG 1683
Score = 28.1 bits (61), Expect = 6.2
Identities = 24/122 (19%), Positives = 62/122 (50%), Gaps = 6/122 (4%)
Query: 13 ELLRQNQRALNRAMRELDRERQKLETQEKKII----ADIKKMAKQGQMDAVRIMAKDLVR 68
++L Q + L + + ++++KL EKK++ + KK K Q + K +V+
Sbjct: 1886 KILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQ 1945
Query: 69 TRRYVRKFVLMRANIQAVSLKIQTL-KSNNSMAQAMKGVTKA-MGTMNRQLKLPQIQKIM 126
++ +R + + +A++L+++ L + + + + ++K +RQ K+ Q+++ +
Sbjct: 1946 GKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQEL 2005
Query: 127 ME 128
E
Sbjct: 2006 FE 2007
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 36.6 bits (83), Expect = 0.018
Identities = 37/186 (19%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 9 KTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVR 68
K+PE++ +++ R+ E ++ +L K+ + I+ + +A +M K +
Sbjct: 239 KSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLT 298
Query: 69 TRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK-LPQIQKIMM 127
+ + +L + + LK N + +K +K ++ QL+ + +Q +
Sbjct: 299 EVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLK 358
Query: 128 EFERQAEIMDMKEEMMNDAID---DAMGDEEDE------------EESDAVVSQVLDELG 172
EF+ + E ++ + +++ND D ++M D D E+ VSQ+ D+L
Sbjct: 359 EFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLD 418
Query: 173 LSLTDE 178
L D+
Sbjct: 419 AELEDK 424
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 36.6 bits (83), Expect = 0.018
Identities = 29/153 (18%), Positives = 73/153 (47%), Gaps = 11/153 (7%)
Query: 30 DRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLK 89
+RE+QKL + ++ D++ + K+ Q + + I+ K+ + R K + +++
Sbjct: 1936 EREKQKLGKEIVRLQKDLRMLRKEHQQE-LEILKKEYDQERE--EKIKQEQEDLE----- 1987
Query: 90 IQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDD 149
LK N+++ Q M+ + ++L++ + I E +AE+++ +E N +
Sbjct: 1988 ---LKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKK 2044
Query: 150 AMGDEEDEEESDAVVSQVLDELGLSLTDELSNL 182
++D + + ++LD +T ++ +L
Sbjct: 2045 IAEKDDDLKRTAKRYEEILDAREEEMTAKVRDL 2077
Score = 30.8 bits (68), Expect = 0.96
Identities = 27/150 (18%), Positives = 60/150 (40%), Gaps = 2/150 (1%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVR--T 69
E+ L+ L ++E D+ ++ + + + ADIK+ + Q + ++ + T
Sbjct: 751 EKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAT 810
Query: 70 RRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEF 129
+ + A +Q L ++T + + A K Q+Q +M +
Sbjct: 811 HEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQL 870
Query: 130 ERQAEIMDMKEEMMNDAIDDAMGDEEDEEE 159
E+Q M+ K + + + + D E+E
Sbjct: 871 EKQNSEMEQKVKSLTQVYESKLEDGNKEQE 900
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 35.4 bits (80), Expect = 0.039
Identities = 43/168 (25%), Positives = 79/168 (47%), Gaps = 28/168 (16%)
Query: 8 RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAK-----QGQMDAV--- 59
RKT E L++ + L A +L E+ K+ T +K+I + K+ K + +M +V
Sbjct: 504 RKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKE 563
Query: 60 RIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKS------NNSMAQAMKGVTKAMGTM 113
R K+ ++ +L R N+ + ++Q+L++ N + Q T A+
Sbjct: 564 RDDLKNKLKAEEEKGNDLLSRVNM--LKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQE 621
Query: 114 NRQLKLPQIQKIMMEFER-QAEIMDMKEEMMNDAIDDAMGDEEDEEES 160
N ++K ++ E ER + ++ DMK AI+D + EDE E+
Sbjct: 622 NNKIK-----ELSQEVERLKLKLKDMK------AIEDDLMKTEDEYET 658
>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
sapiens]
Length = 893
Score = 35.4 bits (80), Expect = 0.039
Identities = 43/168 (25%), Positives = 79/168 (47%), Gaps = 28/168 (16%)
Query: 8 RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAK-----QGQMDAV--- 59
RKT E L++ + L A +L E+ K+ T +K+I + K+ K + +M +V
Sbjct: 264 RKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKE 323
Query: 60 RIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKS------NNSMAQAMKGVTKAMGTM 113
R K+ ++ +L R N+ + ++Q+L++ N + Q T A+
Sbjct: 324 RDDLKNKLKAEEEKGNDLLSRVNM--LKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQE 381
Query: 114 NRQLKLPQIQKIMMEFER-QAEIMDMKEEMMNDAIDDAMGDEEDEEES 160
N ++K ++ E ER + ++ DMK AI+D + EDE E+
Sbjct: 382 NNKIK-----ELSQEVERLKLKLKDMK------AIEDDLMKTEDEYET 418
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 35.4 bits (80), Expect = 0.039
Identities = 43/168 (25%), Positives = 79/168 (47%), Gaps = 28/168 (16%)
Query: 8 RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAK-----QGQMDAV--- 59
RKT E L++ + L A +L E+ K+ T +K+I + K+ K + +M +V
Sbjct: 504 RKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKE 563
Query: 60 RIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKS------NNSMAQAMKGVTKAMGTM 113
R K+ ++ +L R N+ + ++Q+L++ N + Q T A+
Sbjct: 564 RDDLKNKLKAEEEKGNDLLSRVNM--LKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQE 621
Query: 114 NRQLKLPQIQKIMMEFER-QAEIMDMKEEMMNDAIDDAMGDEEDEEES 160
N ++K ++ E ER + ++ DMK AI+D + EDE E+
Sbjct: 622 NNKIK-----ELSQEVERLKLKLKDMK------AIEDDLMKTEDEYET 658
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 35.0 bits (79), Expect = 0.051
Identities = 40/184 (21%), Positives = 82/184 (44%), Gaps = 21/184 (11%)
Query: 3 LLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAK-QGQMDAVRI 61
+L RK E ++Q +R ++ + E+ K+ +K+I + KK+ K + +M+
Sbjct: 507 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE--- 563
Query: 62 MAKDLVRTR-RYVRKFVLMRANIQAVSLKIQTLKSN-NSMAQAMKGVTKAMGTMNRQLKL 119
+L R R + K +S + LK + + + + +T+ +L
Sbjct: 564 KVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTC 623
Query: 120 PQ---IQKIMMEFER------QAEIMD---MKEEMMNDAIDDAMGDEEDEEESDAVVSQV 167
P+ I+++ +E ER Q E+++ MK E D ++ E+D+ +SQ
Sbjct: 624 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKAN---FLSQQ 680
Query: 168 LDEL 171
L+E+
Sbjct: 681 LEEI 684
>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
Length = 1090
Score = 34.7 bits (78), Expect = 0.067
Identities = 41/204 (20%), Positives = 89/204 (43%), Gaps = 20/204 (9%)
Query: 15 LRQNQRALNRAMRE---LDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDL-VRTR 70
L+Q +R +++ E L + ++++E QE K+ K A +GQ+D +IM +L
Sbjct: 159 LKQQERRQQQSISENEKLQKLKERVEAQENKLK---KIRAMRGQVDYSKIMNGNLSAEIE 215
Query: 71 RYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP---QIQKIMM 127
R+ F + +Q L++ L + + KG + N +L P +++++
Sbjct: 216 RFSAMFQEKKQEVQTAILRVDQL--SQQLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQ 273
Query: 128 EF--------ERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDEL 179
E E+ +++ KE + ++ AM D+ E + + + + ++ T
Sbjct: 274 ELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSP 333
Query: 180 SNLPSTGGSLSVAAGGKKAEAAAS 203
+ ST G ++ + +A S
Sbjct: 334 QSPLSTSGRVAAVGPYIQVPSAGS 357
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 34.3 bits (77), Expect = 0.087
Identities = 43/223 (19%), Positives = 96/223 (43%), Gaps = 31/223 (13%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQM-----------DAVR 60
EE+ + QR + AM + + +++ T EK+ +A ++ + D++
Sbjct: 298 EEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMH 357
Query: 61 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTL-KSNNSMAQAMKGVTKAMGTMNRQLKL 119
+D + R+ + L +Q K +TL + +AQ + ++KA + +
Sbjct: 358 RQTED--KNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKA------EERH 409
Query: 120 PQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAV---VSQVLDELGLSLT 176
I++ + + E Q E + +E+ + M +E ++ SD V +S+ + L L L
Sbjct: 410 GNIEERLRQMEAQLE--EKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLK 467
Query: 177 DELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNL 219
+ ++ L L ++ E+A L + D ++ + N+
Sbjct: 468 ERMAALEDKNSLL------REVESAKKQLEETQHDKDQLVLNI 504
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 34.3 bits (77), Expect = 0.087
Identities = 43/223 (19%), Positives = 96/223 (43%), Gaps = 31/223 (13%)
Query: 12 EELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQM-----------DAVR 60
EE+ + QR + AM + + +++ T EK+ +A ++ + D++
Sbjct: 298 EEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMH 357
Query: 61 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTL-KSNNSMAQAMKGVTKAMGTMNRQLKL 119
+D + R+ + L +Q K +TL + +AQ + ++KA + +
Sbjct: 358 RQTED--KNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKA------EERH 409
Query: 120 PQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAV---VSQVLDELGLSLT 176
I++ + + E Q E + +E+ + M +E ++ SD V +S+ + L L L
Sbjct: 410 GNIEERLRQMEAQLE--EKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLK 467
Query: 177 DELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNL 219
+ ++ L L ++ E+A L + D ++ + N+
Sbjct: 468 ERMAALEDKNSLL------REVESAKKQLEETQHDKDQLVLNI 504
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.128 0.325
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,372,242
Number of Sequences: 37866
Number of extensions: 247405
Number of successful extensions: 2732
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 191
Number of HSP's that attempted gapping in prelim test: 2361
Number of HSP's gapped (non-prelim): 531
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.