Guide to the Human Genome
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Search of human proteins with 74229017

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo
sapiens]
         (687 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo sa...  1415   0.0  
gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo sa...  1408   0.0  
gi|45007007 2'-5'oligoadenylate synthetase 3 [Homo sapiens]           575   e-164
gi|74229011 2',5'-oligoadenylate synthetase 1 isoform 2 [Homo sa...   369   e-102
gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo sa...   368   e-102
gi|74229013 2',5'-oligoadenylate synthetase 1 isoform 1 [Homo sa...   368   e-102
gi|74229021 2'-5'-oligoadenylate synthetase 2 isoform 3 [Homo sa...   304   2e-82
gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo...   228   1e-59
gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo...   123   5e-28
gi|7656888 angiopoietin-like 3 precursor [Homo sapiens]                33   0.88 
gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]        33   0.88 
gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]          33   0.88 
gi|156142186 cytokine receptor-like factor 3 [Homo sapiens]            33   1.1  
gi|111548654 hypothetical protein LOC51057 isoform 1 [Homo sapiens]    32   2.0  
gi|111548652 hypothetical protein LOC51057 isoform 2 [Homo sapiens]    32   2.0  
gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]        32   2.6  
gi|18254456 testis-specific gene A2 [Homo sapiens]                     31   3.3  
gi|13376259 nucleoporin 85 [Homo sapiens]                              31   3.3  
gi|28872780 cytosine-5-methyltransferase 3-like protein isoform ...    30   5.7  
gi|28872778 cytosine-5-methyltransferase 3-like protein isoform ...    30   5.7  
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]       30   5.7  
gi|33186882 testis serine protease 2 [Homo sapiens]                    30   5.7  
gi|33946311 solute carrier family 8 (sodium/calcium exchanger), ...    30   5.7  
gi|188528616 testis specific, 10 [Homo sapiens]                        30   7.4  
gi|13376858 testis specific, 10 [Homo sapiens]                         30   7.4  
gi|239751222 PREDICTED: hypothetical protein XP_002347759 [Homo ...    30   7.4  
gi|239745712 PREDICTED: hypothetical protein XP_002343531 [Homo ...    30   7.4  
gi|13129138 mitogen-activated protein kinase associated protein ...    30   9.7  
gi|56788407 mitogen-activated protein kinase associated protein ...    30   9.7  
gi|56788405 mitogen-activated protein kinase associated protein ...    30   9.7  

>gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo
           sapiens]
          Length = 687

 Score = 1415 bits (3662), Expect = 0.0
 Identities = 687/687 (100%), Positives = 687/687 (100%)

Query: 1   MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
           MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG
Sbjct: 1   MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60

Query: 61  GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
           GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI
Sbjct: 61  GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120

Query: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC 180
           QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC
Sbjct: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC 180

Query: 181 FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD 240
           FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD
Sbjct: 181 FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD 240

Query: 241 NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN 300
           NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN
Sbjct: 241 NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN 300

Query: 301 VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK 360
           VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK
Sbjct: 301 VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK 360

Query: 361 CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS 420
           CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS
Sbjct: 361 CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS 420

Query: 421 YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF 480
           YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF
Sbjct: 421 YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF 480

Query: 481 DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK 540
           DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK
Sbjct: 481 DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK 540

Query: 541 DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT 600
           DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT
Sbjct: 541 DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT 600

Query: 601 QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA 660
           QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA
Sbjct: 601 QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA 660

Query: 661 KEWLSSPCFKDGTGNPIPPWKVPVKVI 687
           KEWLSSPCFKDGTGNPIPPWKVPVKVI
Sbjct: 661 KEWLSSPCFKDGTGNPIPPWKVPVKVI 687


>gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo
           sapiens]
          Length = 719

 Score = 1408 bits (3645), Expect = 0.0
 Identities = 683/683 (100%), Positives = 683/683 (100%)

Query: 1   MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
           MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG
Sbjct: 1   MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60

Query: 61  GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
           GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI
Sbjct: 61  GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120

Query: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC 180
           QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC
Sbjct: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC 180

Query: 181 FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD 240
           FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD
Sbjct: 181 FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD 240

Query: 241 NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN 300
           NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN
Sbjct: 241 NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN 300

Query: 301 VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK 360
           VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK
Sbjct: 301 VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK 360

Query: 361 CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS 420
           CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS
Sbjct: 361 CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS 420

Query: 421 YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF 480
           YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF
Sbjct: 421 YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF 480

Query: 481 DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK 540
           DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK
Sbjct: 481 DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK 540

Query: 541 DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT 600
           DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT
Sbjct: 541 DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT 600

Query: 601 QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA 660
           QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA
Sbjct: 601 QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA 660

Query: 661 KEWLSSPCFKDGTGNPIPPWKVP 683
           KEWLSSPCFKDGTGNPIPPWKVP
Sbjct: 661 KEWLSSPCFKDGTGNPIPPWKVP 683


>gi|45007007 2'-5'oligoadenylate synthetase 3 [Homo sapiens]
          Length = 1087

 Score =  575 bits (1482), Expect = e-164
 Identities = 337/703 (47%), Positives = 446/703 (63%), Gaps = 47/703 (6%)

Query: 8    LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKT 67
            LS +P ++L  FIQ++LKP  + Q  + + ++ I   L E         V+ GGS+GR T
Sbjct: 408  LSQIPTKELDRFIQDHLKPSPQFQEQVKKAIDIILRCLHE-NCVHKASRVSKGGSFGRGT 466

Query: 68   VLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKW-------LKNNFEI 120
             LR   D  L++F +    ++DQ   + +ILD+   +L+      W       L   F  
Sbjct: 467  DLRDGCDVELIIFLNCFTDYKDQGPRRAEILDEMRAQLE-----SWWQDQVPSLSLQFPE 521

Query: 121  QKSLDGFTIQVFTKNQRISFEV--LAAFNA---LSLNDNPSPWIYRELKRSLDKTNASPG 175
            Q   +    Q+ +   +   +V  L AF+A   LS    P+P +Y  L  S        G
Sbjct: 522  QNVPEALQFQLVSTALKSWTDVSLLPAFDAVGQLSSGTKPNPQVYSRLLTS----GCQEG 577

Query: 176  EFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDL----PSLSP-YALELLTV 230
            E   CF EL++ F + RP KLK+LILL+KHW++Q   + K       SL P YALELLT+
Sbjct: 578  EHKACFAELRRNFMNIRPVKLKNLILLVKHWYRQVAAQNKGKGPAPASLPPAYALELLTI 637

Query: 231  YAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPV 290
            +AWEQGCR+D F++A+G RTVL L++  ++LC+YW VNY+ ED  +R  LL QL+  RP+
Sbjct: 638  FAWEQGCRQDCFNMAQGFRTVLGLVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRKPRPL 697

Query: 291  ILDPVDPTNNVSGDKICWQWLKKEA-----QTWLTSPNLDNELPAPSWNVLPAPLFTTPG 345
            +LDP DPT NV      W+ L +EA     Q    S +  +  P   W+V+PA L+ TP 
Sbjct: 698  VLDPADPTWNVGHGS--WELLAQEAAALGMQACFLSRDGTSVQP---WDVMPALLYQTPA 752

Query: 346  HLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAK-IQIVRGGSTAKGTALK 404
              LDKFI EFLQPN+ FL Q++ AV+ I +FLKENCFR S  K I++V+GGS+AKGTAL+
Sbjct: 753  GDLDKFISEFLQPNRQFLAQVNKAVDTICSFLKENCFRNSPIKVIKVVKGGSSAKGTALR 812

Query: 405  TGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRV 464
              SDADLVVF +    +T Q N+R +I+ EI  QL+A   ++E + EV FE  KW+ PRV
Sbjct: 813  GRSDADLVVFLSCFSQFTEQGNKRAEIISEIRAQLEAC--QQERQFEVKFEVSKWENPRV 870

Query: 465  LSFSLKSK-VLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTC 523
            LSFSL S+ +L++SV FDVLPAF+ALGQL SGS PS +VY  LI  Y ++    GE+STC
Sbjct: 871  LSFSLTSQTMLDQSVDFDVLPAFDALGQLVSGSRPSSQVYVDLIHSYSNA----GEYSTC 926

Query: 524  FTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGV 583
            FT LQR+FI SRPTKLK LIRLVKHWY++C +  K +GSLPP++ LELLT+YAWEQG   
Sbjct: 927  FTELQRDFIISRPTKLKSLIRLVKHWYQQCTKISKGRGSLPPQHGLELLTVYAWEQGGKD 986

Query: 584  PDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTG 643
              F+ AEGFRTVLELVTQY+QLCI+W +NYN +D+TV  FL  QLQK RP+ILDPA+PTG
Sbjct: 987  SQFNMAEGFRTVLELVTQYRQLCIYWTINYNAKDKTVGDFLKQQLQKPRPIILDPADPTG 1046

Query: 644  DVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPVKV 686
            ++G   R  W LLAKEA    S+ C     G PI PW V   V
Sbjct: 1047 NLGHNAR--WDLLAKEAAACTSALCCMGRNGIPIQPWPVKAAV 1087



 Score =  445 bits (1145), Expect = e-125
 Identities = 287/764 (37%), Positives = 398/764 (52%), Gaps = 113/764 (14%)

Query: 8   LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP-----EQFPLVQGVAIGGS 62
           L S PA  L  F+   L+P +E        +  +   L+E         P V     GGS
Sbjct: 3   LYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKGGS 62

Query: 63  YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFE--- 119
            GR T L+G  D  LV+F    K + DQ+  + +IL +    L+      W +N      
Sbjct: 63  SGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLE-----SWWQNPVPGLR 117

Query: 120 ---IQKSLDG---FTIQVFTKNQRISFEVLAAFNALSLNDN---PSPWIYRELKRSLDKT 170
               ++S+ G   F +        +   ++ AFN L    +   P P +Y  L  S    
Sbjct: 118 LTFPEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLNS---- 173

Query: 171 NASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHW-HQQCQKKI--KDLPSLSPYALEL 227
               GE A CFTEL++ F + RP KLK+LILL+KHW HQ C + +  + LP +  YALEL
Sbjct: 174 GCQGGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPV--YALEL 231

Query: 228 LTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSA 287
           LT++AWEQGC+KD F +AEG+RTVL LI+  + LC++W VNY FED  +   L  QL+  
Sbjct: 232 LTIFAWEQGCKKDAFSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRP 291

Query: 288 RPVILDPVDPTNNVSGDKICWQW--LKKEA-----------------QTWL--------- 319
           RPVILDP DPT ++ G+   W W  L +EA                 Q+W          
Sbjct: 292 RPVILDPADPTWDL-GNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGPGLPRAGC 350

Query: 320 --------TSPNLDNELPAPSWNVL-----------PAP------------------LFT 342
                     PN      + S N +           PAP                  L  
Sbjct: 351 SGLGHPIQLDPNQKTPENSKSLNAVYPRAGSKPPSCPAPGPTGAASIVPSVPGMALDLSQ 410

Query: 343 TPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTA 402
            P   LD+FI++ L+P+  F EQ+  A++II   L ENC  +++   ++ +GGS  +GT 
Sbjct: 411 IPTKELDRFIQDHLKPSPQFQEQVKKAIDIILRCLHENCVHKAS---RVSKGGSFGRGTD 467

Query: 403 LKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAP 462
           L+ G D +L++F N    Y  Q   R +I+ E+  QL+++W+++   L + F  P+   P
Sbjct: 468 LRDGCDVELIIFLNCFTDYKDQGPRRAEILDEMRAQLESWWQDQVPSLSLQF--PEQNVP 525

Query: 463 RVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFST 522
             L F L S  L       +LPAF+A+GQLSSG+ P+P+VY+ L+    +S    GE   
Sbjct: 526 EALQFQLVSTALKSWTDVSLLPAFDAVGQLSSGTKPNPQVYSRLL----TSGCQEGEHKA 581

Query: 523 CFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKG----SLPPKYALELLTIYAWE 578
           CF  L+RNF+  RP KLK+LI LVKHWY++   + K KG    SLPP YALELLTI+AWE
Sbjct: 582 CFAELRRNFMNIRPVKLKNLILLVKHWYRQVAAQNKGKGPAPASLPPAYALELLTIFAWE 641

Query: 579 QGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDP 638
           QG     F+ A+GFRTVL LV Q+QQLC++W VNY+ ED  +R  LL QL+K RP++LDP
Sbjct: 642 QGCRQDCFNMAQGFRTVLGLVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRKPRPLVLDP 701

Query: 639 AEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKV 682
           A+PT +VG G    W LLA+EA       CF    G  + PW V
Sbjct: 702 ADPTWNVGHGS---WELLAQEAAALGMQACFLSRDGTSVQPWDV 742



 Score =  302 bits (774), Expect = 6e-82
 Identities = 159/347 (45%), Positives = 215/347 (61%), Gaps = 9/347 (2%)

Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAK---IQIVRGGS 396
           L++TP   LD+F+   LQP K F+E+   A+  +   L+E   R   A    ++ V+GGS
Sbjct: 3   LYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKGGS 62

Query: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456
           + +GTALK G D++LV+F +  KSY  Q+  R +I+ E+   L+++W+     L ++F  
Sbjct: 63  SGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLESWWQNPVPGLRLTF-- 120

Query: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516
           P+   P  L F L S  L + +   ++PAFN LGQ  SG  P P+VY+ L++    S   
Sbjct: 121 PEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLN----SGCQ 176

Query: 517 GGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYA 576
           GGE + CFT L+RNF+  RP KLK+LI LVKHWY +   +   K +LPP YALELLTI+A
Sbjct: 177 GGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPVYALELLTIFA 236

Query: 577 WEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVIL 636
           WEQG     F  AEG RTVL L+ Q+Q LC+FW VNY FED  V +FL  QL++ RPVIL
Sbjct: 237 WEQGCKKDAFSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRPRPVIL 296

Query: 637 DPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVP 683
           DPA+PT D+G G  W W LLA+EA      PCF  G G+P+  WK P
Sbjct: 297 DPADPTWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGP 343


>gi|74229011 2',5'-oligoadenylate synthetase 1 isoform 2 [Homo
           sapiens]
          Length = 364

 Score =  369 bits (946), Expect = e-102
 Identities = 187/350 (53%), Positives = 249/350 (71%), Gaps = 9/350 (2%)

Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKI---QIVRGGS 396
           L  TP   LDKFI+++L P+ CF  QI+ A++II  FLKE CFR S+  +   ++V+GGS
Sbjct: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63

Query: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456
           + KGT L+  SDADLVVF + L ++  Q N R + ++EI  QL+A  RE+   ++   + 
Sbjct: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123

Query: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516
           P+W  PR LSF L S  L E V FDVLPAF+ALGQL+ G  P+P++Y  LI+  + +DL 
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIE--ECTDLQ 181

Query: 517 G-GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIY 575
             GEFSTCFT LQR+F++ RPTKLK LIRLVKHWY+ C++KL   G LPP+YALELLT+Y
Sbjct: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKL---GKLPPQYALELLTVY 238

Query: 576 AWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVI 635
           AWE+GS    F+TA+GFRTVLELV  YQQLCI+W   Y+F++  + K+L  QL K RPVI
Sbjct: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298

Query: 636 LDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPVK 685
           LDPA+PTG++GGGD   W  LA+EA+ WL+ PCFK+  G+P+  W + V+
Sbjct: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVR 348



 Score =  231 bits (589), Expect = 2e-60
 Identities = 142/349 (40%), Positives = 191/349 (54%), Gaps = 20/349 (5%)

Query: 8   LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62
           L + PA+ L  FI++YL P    +  I+  ++ IC  L+E       +P+ V  V  GGS
Sbjct: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63

Query: 63  YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122
            G+ T LRG SD  LV+F S L  FQDQ   + + + +   +L+ C   +     FE+Q 
Sbjct: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123

Query: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLDKTNAS 173
              G      F +      + + F+VL AF+AL        P+P IY +L          
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKE 183

Query: 174 PGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAW 233
            GEF+ CFTELQ+ F   RP KLK LI L+KHW+Q C+KK+  LP    YALELLTVYAW
Sbjct: 184 -GEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPP--QYALELLTVYAW 240

Query: 234 EQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILD 293
           E+G  K +F+ A+G RTVLEL+   ++LCIYW   Y+F++  I   L  QL   RPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300

Query: 294 PVDPTNNV-SGDKICWQWLKKEAQTWLTSPNLDN--ELPAPSWNVLPAP 339
           P DPT N+  GD   W+ L +EA+ WL  P   N    P  SW +L  P
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVRP 349


>gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo
           sapiens]
          Length = 414

 Score =  368 bits (945), Expect = e-102
 Identities = 186/345 (53%), Positives = 246/345 (71%), Gaps = 9/345 (2%)

Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKI---QIVRGGS 396
           L  TP   LDKFI+++L P+ CF  QI+ A++II  FLKE CFR S+  +   ++V+GGS
Sbjct: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63

Query: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456
           + KGT L+  SDADLVVF + L ++  Q N R + ++EI  QL+A  RE+   ++   + 
Sbjct: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123

Query: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516
           P+W  PR LSF L S  L E V FDVLPAF+ALGQL+ G  P+P++Y  LI+  + +DL 
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIE--ECTDLQ 181

Query: 517 G-GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIY 575
             GEFSTCFT LQR+F++ RPTKLK LIRLVKHWY+ C++KL   G LPP+YALELLT+Y
Sbjct: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKL---GKLPPQYALELLTVY 238

Query: 576 AWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVI 635
           AWE+GS    F+TA+GFRTVLELV  YQQLCI+W   Y+F++  + K+L  QL K RPVI
Sbjct: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298

Query: 636 LDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPW 680
           LDPA+PTG++GGGD   W  LA+EA+ WL+ PCFK+  G+P+  W
Sbjct: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343



 Score =  230 bits (586), Expect = 4e-60
 Identities = 144/357 (40%), Positives = 194/357 (54%), Gaps = 23/357 (6%)

Query: 8   LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62
           L + PA+ L  FI++YL P    +  I+  ++ IC  L+E       +P+ V  V  GGS
Sbjct: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63

Query: 63  YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122
            G+ T LRG SD  LV+F S L  FQDQ   + + + +   +L+ C   +     FE+Q 
Sbjct: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123

Query: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLDKTNAS 173
              G      F +      + + F+VL AF+AL        P+P IY +L          
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKE 183

Query: 174 PGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAW 233
            GEF+ CFTELQ+ F   RP KLK LI L+KHW+Q C+KK+  LP    YALELLTVYAW
Sbjct: 184 -GEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPP--QYALELLTVYAW 240

Query: 234 EQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILD 293
           E+G  K +F+ A+G RTVLEL+   ++LCIYW   Y+F++  I   L  QL   RPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300

Query: 294 PVDPTNNV-SGDKICWQWLKKEAQTWLTSPNLDN--ELPAPSWNVLPAPLFTTPGHL 347
           P DPT N+  GD   W+ L +EA+ WL  P   N    P  SW +L      TPG +
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQ---HTPGSI 354


>gi|74229013 2',5'-oligoadenylate synthetase 1 isoform 1 [Homo
           sapiens]
          Length = 400

 Score =  368 bits (945), Expect = e-102
 Identities = 186/345 (53%), Positives = 246/345 (71%), Gaps = 9/345 (2%)

Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKI---QIVRGGS 396
           L  TP   LDKFI+++L P+ CF  QI+ A++II  FLKE CFR S+  +   ++V+GGS
Sbjct: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63

Query: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456
           + KGT L+  SDADLVVF + L ++  Q N R + ++EI  QL+A  RE+   ++   + 
Sbjct: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123

Query: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516
           P+W  PR LSF L S  L E V FDVLPAF+ALGQL+ G  P+P++Y  LI+  + +DL 
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIE--ECTDLQ 181

Query: 517 G-GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIY 575
             GEFSTCFT LQR+F++ RPTKLK LIRLVKHWY+ C++KL   G LPP+YALELLT+Y
Sbjct: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKL---GKLPPQYALELLTVY 238

Query: 576 AWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVI 635
           AWE+GS    F+TA+GFRTVLELV  YQQLCI+W   Y+F++  + K+L  QL K RPVI
Sbjct: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298

Query: 636 LDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPW 680
           LDPA+PTG++GGGD   W  LA+EA+ WL+ PCFK+  G+P+  W
Sbjct: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343



 Score =  229 bits (585), Expect = 5e-60
 Identities = 141/346 (40%), Positives = 190/346 (54%), Gaps = 20/346 (5%)

Query: 8   LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62
           L + PA+ L  FI++YL P    +  I+  ++ IC  L+E       +P+ V  V  GGS
Sbjct: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63

Query: 63  YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122
            G+ T LRG SD  LV+F S L  FQDQ   + + + +   +L+ C   +     FE+Q 
Sbjct: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123

Query: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLDKTNAS 173
              G      F +      + + F+VL AF+AL        P+P IY +L          
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKE 183

Query: 174 PGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAW 233
            GEF+ CFTELQ+ F   RP KLK LI L+KHW+Q C+KK+  LP    YALELLTVYAW
Sbjct: 184 -GEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPP--QYALELLTVYAW 240

Query: 234 EQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILD 293
           E+G  K +F+ A+G RTVLEL+   ++LCIYW   Y+F++  I   L  QL   RPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300

Query: 294 PVDPTNNV-SGDKICWQWLKKEAQTWLTSPNLDN--ELPAPSWNVL 336
           P DPT N+  GD   W+ L +EA+ WL  P   N    P  SW +L
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILL 346


>gi|74229021 2'-5'-oligoadenylate synthetase 2 isoform 3 [Homo
           sapiens]
          Length = 172

 Score =  304 bits (778), Expect = 2e-82
 Identities = 150/150 (100%), Positives = 150/150 (100%)

Query: 1   MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
           MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG
Sbjct: 1   MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60

Query: 61  GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
           GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI
Sbjct: 61  GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120

Query: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALS 150
           QKSLDGFTIQVFTKNQRISFEVLAAFNALS
Sbjct: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALS 150



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 16/156 (10%)

Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAK 399
           L + P   L  FI+E+L+P +     ID  VN I   L+E    Q      +  GGS  +
Sbjct: 8   LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--EQFPLVQGVAIGGSYGR 65

Query: 400 GTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLK----AFWREKEEELEVSFE 455
            T L+  SD  LV+F + LK +  QK  +  I+ +  ++LK      W +   E++ S +
Sbjct: 66  KTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLD 125

Query: 456 PPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQ 491
                      F+++    N+ +SF+VL AFNAL +
Sbjct: 126 ----------GFTIQVFTKNQRISFEVLAAFNALSK 151


>gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo
           sapiens]
          Length = 514

 Score =  228 bits (582), Expect = 1e-59
 Identities = 127/352 (36%), Positives = 201/352 (57%), Gaps = 19/352 (5%)

Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFR------QSTAKIQIVR 393
           L++TP   LD F+ ++LQP++ + E++  AV  +  FL++  F+      Q    +++V+
Sbjct: 7   LYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVK 66

Query: 394 GGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVS 453
            GS   GT L++  + +LV F +   S+         +++ I    K  W + ++ L++ 
Sbjct: 67  VGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIW---KTMW-QSQDLLDLG 122

Query: 454 FEPPKW--KAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYK 511
            E  +   + P  L F+++++   E ++  ++PA+ ALG     S P PEVY  LI   K
Sbjct: 123 LEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLI---K 179

Query: 512 SSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALEL 571
           +   PG  F   F+ LQRNF++ RPTKLK L+RLVKHWY++  +   P+ +LPP YALEL
Sbjct: 180 ACGGPGN-FCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238

Query: 572 LTIYAWEQGSGVPD-FDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQK 630
           LTIYAWE G+   + F   EGF TV++L+ +Y+ +CI+W   Y   +  +   +  QL+K
Sbjct: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298

Query: 631 TRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKV 682
            RP+ILDPA+PT +V  G R  W ++A+ A + L   C  D   NPI  W V
Sbjct: 299 ERPIILDPADPTLNVAEGYR--WDIVAQRASQCLKQDCCYDNRENPISSWNV 348



 Score =  169 bits (429), Expect = 6e-42
 Identities = 122/351 (34%), Positives = 179/351 (50%), Gaps = 30/351 (8%)

Query: 7   QLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--------EQFPLVQGVA 58
           +L S PA +L  F+ ++L+P+ E +  + + V T+ + L++         +Q   V  V 
Sbjct: 6   ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65

Query: 59  IGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILD-------KTGDKLKFCLFT 111
             GS+G  TVLR   +  LV F S    FQ+  +  +D+L        ++ D L   L  
Sbjct: 66  KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGL-- 123

Query: 112 KWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLD 168
           + L+    +  +L  FTIQ     + I+  ++ A+ AL     N  P P +Y     SL 
Sbjct: 124 EDLRMEQRVPDALV-FTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYV----SLI 178

Query: 169 KTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSP-YALEL 227
           K    PG F   F+ELQ+ F  +RP KLK L+ L+KHW+QQ  K      +L P YALEL
Sbjct: 179 KACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238

Query: 228 LTVYAWEQGCRKD-NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQS 286
           LT+YAWE G  +D NF + EG  TV++L+   E +CIYW   Y   +  I + +  QL+ 
Sbjct: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298

Query: 287 ARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNL--DNELPAPSWNV 335
            RP+ILDP DPT NV+ +   W  + + A   L       + E P  SWNV
Sbjct: 299 ERPIILDPADPTLNVA-EGYRWDIVAQRASQCLKQDCCYDNRENPISSWNV 348


>gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo
           sapiens]
          Length = 255

 Score =  123 bits (309), Expect = 5e-28
 Identities = 72/221 (32%), Positives = 123/221 (55%), Gaps = 16/221 (7%)

Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFR------QSTAKIQIVR 393
           L++TP   LD F+ ++LQP++ + E++  AV  +  FL++  F+      Q    +++V+
Sbjct: 7   LYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVK 66

Query: 394 GGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVS 453
            GS   GT L++  + +LV F +   S+         +++ I    K  W + ++ L++ 
Sbjct: 67  VGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIW---KTMW-QSQDLLDLG 122

Query: 454 FEPPKW--KAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYK 511
            E  +   + P  L F+++++   E ++  ++PA+ ALG     S P PEVY  LI   K
Sbjct: 123 LEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLI---K 179

Query: 512 SSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKE 552
           +   PG  F   F+ LQRNF++ RPTKLK L+RLVKHWY++
Sbjct: 180 ACGGPGN-FCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQ 219



 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 70/221 (31%), Positives = 109/221 (49%), Gaps = 25/221 (11%)

Query: 7   QLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--------EQFPLVQGVA 58
           +L S PA +L  F+ ++L+P+ E +  + + V T+ + L++         +Q   V  V 
Sbjct: 6   ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65

Query: 59  IGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILD-------KTGDKLKFCLFT 111
             GS+G  TVLR   +  LV F S    FQ+  +  +D+L        ++ D L   L  
Sbjct: 66  KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGL-- 123

Query: 112 KWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLD 168
           + L+    +  +L  FTIQ     + I+  ++ A+ AL     N  P P +Y     SL 
Sbjct: 124 EDLRMEQRVPDALV-FTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYV----SLI 178

Query: 169 KTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQ 209
           K    PG F   F+ELQ+ F  +RP KLK L+ L+KHW+QQ
Sbjct: 179 KACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQ 219


>gi|7656888 angiopoietin-like 3 precursor [Homo sapiens]
          Length = 460

 Score = 33.1 bits (74), Expect = 0.88
 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 8/88 (9%)

Query: 401 TALKT---GSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPP 457
           T+LKT     D  +     +++    Q N++H  +KEI  QL+    ++  E+ +S +P 
Sbjct: 162 TSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKP- 220

Query: 458 KWKAPRVLSFSLKSKVLNESVSFDVLPA 485
             +APR   F   +++ N  V  D +PA
Sbjct: 221 --RAPRTTPFLQLNEIRN--VKHDGIPA 244


>gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
          Length = 770

 Score = 33.1 bits (74), Expect = 0.88
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 9/100 (9%)

Query: 478 VSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRN-----FI 532
           VS   +   + LG     +  S + ++    +Y S  LP  +    FT L        FI
Sbjct: 203 VSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFI 262

Query: 533 RSRPTKLKDLIRLVKHWYK-ECERKLKPKGSLPPKYALEL 571
            SRP   KD+++L++H Y  +C   LK    L P + L++
Sbjct: 263 NSRPVHQKDILKLIRHHYNLKC---LKESTRLYPVFFLKI 299


>gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]
          Length = 932

 Score = 33.1 bits (74), Expect = 0.88
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 9/100 (9%)

Query: 478 VSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRN-----FI 532
           VS   +   + LG     +  S + ++    +Y S  LP  +    FT L        FI
Sbjct: 203 VSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFI 262

Query: 533 RSRPTKLKDLIRLVKHWYK-ECERKLKPKGSLPPKYALEL 571
            SRP   KD+++L++H Y  +C   LK    L P + L++
Sbjct: 263 NSRPVHQKDILKLIRHHYNLKC---LKESTRLYPVFFLKI 299


>gi|156142186 cytokine receptor-like factor 3 [Homo sapiens]
          Length = 442

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 15/36 (41%), Positives = 24/36 (66%)

Query: 14  QKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPE 49
           Q++    QE +KP ++CQ LI+  VNT  D+++E E
Sbjct: 79  QEVDTIEQETIKPLDDCQKLIEHGVNTAEDLVREGE 114


>gi|111548654 hypothetical protein LOC51057 isoform 1 [Homo sapiens]
          Length = 587

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 7/74 (9%)

Query: 372 IIRTFLKEN--CFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERH 429
           II +FL +N  CF Q T K++     S+     L+  S  D  +F+  +    ++  ERH
Sbjct: 15  IILSFLAQNKLCFIQFTKKME-----SSDVNKRLEKLSALDYKIFYYEIPGPINKTTERH 69

Query: 430 KIVKEIHEQLKAFW 443
             +  +H+++  +W
Sbjct: 70  LAINCVHDRVVCWW 83


>gi|111548652 hypothetical protein LOC51057 isoform 2 [Homo sapiens]
          Length = 746

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 7/74 (9%)

Query: 372 IIRTFLKEN--CFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERH 429
           II +FL +N  CF Q T K++     S+     L+  S  D  +F+  +    ++  ERH
Sbjct: 174 IILSFLAQNKLCFIQFTKKME-----SSDVNKRLEKLSALDYKIFYYEIPGPINKTTERH 228

Query: 430 KIVKEIHEQLKAFW 443
             +  +H+++  +W
Sbjct: 229 LAINCVHDRVVCWW 242


>gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]
          Length = 893

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 9/69 (13%)

Query: 509 LYKSSDLPGGEFSTCFTVLQRN-----FIRSRPTKLKDLIRLVKHWYK-ECERKLKPKGS 562
           +Y S  LP  +    FT L        FI SRP   KD+++L++H Y  +C   LK    
Sbjct: 195 IYLSGFLPKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKC---LKESTR 251

Query: 563 LPPKYALEL 571
           L P + L++
Sbjct: 252 LYPVFFLKI 260


>gi|18254456 testis-specific gene A2 [Homo sapiens]
          Length = 309

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 445 EKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYA 504
           E+EEE E+    PKWKA ++   +L +  L +  +    P  +A G  S+G  P  E  A
Sbjct: 195 EEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPGAESAGE-PGEEAQA 253

Query: 505 GLIDLYKSSDL-PGGE 519
            L       D+ PG E
Sbjct: 254 LLEGFEGEMDMRPGDE 269


>gi|13376259 nucleoporin 85 [Homo sapiens]
          Length = 656

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 7/76 (9%)

Query: 162 ELKRSLDK-TNASPGEFAVC--FTELQQKFFDNRPGK---LKDLILLIKHWHQQCQKKIK 215
           E ++ L K  +ASP    +C    +L +      PG    L +L L  +HWH++C++ ++
Sbjct: 211 EARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQ 270

Query: 216 DLP-SLSPYALELLTV 230
           D   + SP+   LL +
Sbjct: 271 DSTFATSPHLESLLKI 286


>gi|28872780 cytosine-5-methyltransferase 3-like protein isoform 2
           [Homo sapiens]
          Length = 386

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 10/62 (16%)

Query: 438 QLKAFW-REKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGS 496
           QLKAF+ RE E  LE+    P W+   V   SL   +  E  S         LG L SGS
Sbjct: 163 QLKAFYDRESENPLEMFETVPVWRRQPVRVLSLFEDIKKELTS---------LGFLESGS 213

Query: 497 TP 498
            P
Sbjct: 214 DP 215


>gi|28872778 cytosine-5-methyltransferase 3-like protein isoform 1
           [Homo sapiens]
          Length = 387

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 10/62 (16%)

Query: 438 QLKAFW-REKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGS 496
           QLKAF+ RE E  LE+    P W+   V   SL   +  E  S         LG L SGS
Sbjct: 163 QLKAFYDRESENPLEMFETVPVWRRQPVRVLSLFEDIKKELTS---------LGFLESGS 213

Query: 497 TP 498
            P
Sbjct: 214 DP 215


>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
          Length = 1495

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 17/62 (27%), Positives = 26/62 (41%), Gaps = 1/62 (1%)

Query: 518 GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAW 577
           G  + C T      +     KL  L+   ++W K C      +G LPP Y   L+ I+  
Sbjct: 412 GNENACLTTKHLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPP-YVFALMAIFFL 470

Query: 578 EQ 579
           +Q
Sbjct: 471 QQ 472


>gi|33186882 testis serine protease 2 [Homo sapiens]
          Length = 293

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 16/64 (25%), Positives = 32/64 (50%), Gaps = 8/64 (12%)

Query: 20  IQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVL 79
           + +Y+  YEEC  +I + +++  DV        +++G+  G     K   +G+S G L  
Sbjct: 222 VDQYIMCYEECNKIIQKALSSTKDV--------IIKGMVCGYKEQGKDSCQGDSGGRLAC 273

Query: 80  FFSD 83
            ++D
Sbjct: 274 EYND 277


>gi|33946311 solute carrier family 8 (sodium/calcium exchanger),
           member 3 isoform C precursor [Homo sapiens]
          Length = 927

 Score = 30.4 bits (67), Expect = 5.7
 Identities = 42/183 (22%), Positives = 69/183 (37%), Gaps = 16/183 (8%)

Query: 322 PNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENC 381
           P + N LP P   VL +P   T   L D     F    +C    +  ++ ++        
Sbjct: 500 PAIFNSLPLPR-AVLASPCVATVTILDDDHAGIFTF--ECDTIHVSESIGVMEV----KV 552

Query: 382 FRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKA 441
            R S A+  ++    T +GTA   G D +        K+  + K  R KIV E       
Sbjct: 553 LRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEE----- 607

Query: 442 FWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPA--FNALGQLSSGSTPS 499
              E++E   ++   PKW    + +  L   V +  ++ +   A     +G+   G  P 
Sbjct: 608 --YERQENFFIALGEPKWMERGISALLLSPDVTDRKLTMEEEEAKRIAEMGKPVLGEHPK 665

Query: 500 PEV 502
            EV
Sbjct: 666 LEV 668


>gi|188528616 testis specific, 10 [Homo sapiens]
          Length = 698

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 12/111 (10%)

Query: 348 LDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQS-----TAKIQIVRGGSTAKGTA 402
           L   +K     N+  +EQ+  A      +  EN  RQS     T K++++   + A+G  
Sbjct: 399 LKNILKSEESENRQMMEQLRKANEDAENW--ENKARQSEADNNTLKLELIT--AEAEGNR 454

Query: 403 LKTGSDA---DLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEEL 450
           LK   D+   ++    N+ +SY SQ +  HK V ++ E+L+    EK   L
Sbjct: 455 LKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSAL 505


>gi|13376858 testis specific, 10 [Homo sapiens]
          Length = 698

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 12/111 (10%)

Query: 348 LDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQS-----TAKIQIVRGGSTAKGTA 402
           L   +K     N+  +EQ+  A      +  EN  RQS     T K++++   + A+G  
Sbjct: 399 LKNILKSEESENRQMMEQLRKANEDAENW--ENKARQSEADNNTLKLELIT--AEAEGNR 454

Query: 403 LKTGSDA---DLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEEL 450
           LK   D+   ++    N+ +SY SQ +  HK V ++ E+L+    EK   L
Sbjct: 455 LKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSAL 505


>gi|239751222 PREDICTED: hypothetical protein XP_002347759 [Homo
           sapiens]
          Length = 95

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 626 SQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWL 664
           +QL + R  +L PA+P  D GG         + E KEWL
Sbjct: 28  TQLCQRRGTVLAPAQPRADSGGSGEVVQSQSSVERKEWL 66


>gi|239745712 PREDICTED: hypothetical protein XP_002343531 [Homo
           sapiens]
          Length = 95

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 626 SQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWL 664
           +QL + R  +L PA+P  D GG         + E KEWL
Sbjct: 28  TQLCQRRGTVLAPAQPRADSGGSGEVVQSQSSVERKEWL 66


>gi|13129138 mitogen-activated protein kinase associated protein 1
           isoform 2 [Homo sapiens]
          Length = 486

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 38/234 (16%)

Query: 419 KSYTSQKNERHKIVKEIHEQLKAF---WREKE-----EELEVSFE-------PPKWKAPR 463
           +S T+Q+ ER +  KE   Q+K     W+E+      +EL+  FE       PP      
Sbjct: 83  RSNTAQRLERLR--KERQNQIKCKNIQWKERNSKQSAQELKSLFEKKSLKEKPPISGKQS 140

Query: 464 VLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTC 523
           +LS  L+   L  +  F+    F+  G + + +T   +VY   + L+ S D         
Sbjct: 141 ILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY---LPLHSSQD--------- 188

Query: 524 FTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGV 583
             +L    +     +++DLI L+   Y    R+ K   ++   Y L +      E  +  
Sbjct: 189 -RLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNV-SAYCLHIAEDDG-EVDTDF 245

Query: 584 PDFDTAE-----GFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTR 632
           P  D+ E     GF T L LV +Y    +  K +          F L Q+  T+
Sbjct: 246 PPLDSNEPIHKFGFST-LALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTK 298


>gi|56788407 mitogen-activated protein kinase associated protein 1
           isoform 1 [Homo sapiens]
          Length = 522

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 38/234 (16%)

Query: 419 KSYTSQKNERHKIVKEIHEQLKAF---WREKE-----EELEVSFE-------PPKWKAPR 463
           +S T+Q+ ER +  KE   Q+K     W+E+      +EL+  FE       PP      
Sbjct: 83  RSNTAQRLERLR--KERQNQIKCKNIQWKERNSKQSAQELKSLFEKKSLKEKPPISGKQS 140

Query: 464 VLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTC 523
           +LS  L+   L  +  F+    F+  G + + +T   +VY   + L+ S D         
Sbjct: 141 ILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY---LPLHSSQD--------- 188

Query: 524 FTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGV 583
             +L    +     +++DLI L+   Y    R+ K   ++   Y L +      E  +  
Sbjct: 189 -RLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNV-SAYCLHIAEDDG-EVDTDF 245

Query: 584 PDFDTAE-----GFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTR 632
           P  D+ E     GF T L LV +Y    +  K +          F L Q+  T+
Sbjct: 246 PPLDSNEPIHKFGFST-LALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTK 298


>gi|56788405 mitogen-activated protein kinase associated protein 1
           isoform 3 [Homo sapiens]
          Length = 475

 Score = 29.6 bits (65), Expect = 9.7
 Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 38/234 (16%)

Query: 419 KSYTSQKNERHKIVKEIHEQLKAF---WREKE-----EELEVSFE-------PPKWKAPR 463
           +S T+Q+ ER +  KE   Q+K     W+E+      +EL+  FE       PP      
Sbjct: 83  RSNTAQRLERLR--KERQNQIKCKNIQWKERNSKQSAQELKSLFEKKSLKEKPPISGKQS 140

Query: 464 VLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTC 523
           +LS  L+   L  +  F+    F+  G + + +T   +VY   + L+ S D         
Sbjct: 141 ILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY---LPLHSSQD--------- 188

Query: 524 FTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGV 583
             +L    +     +++DLI L+   Y    R+ K   ++   Y L +      E  +  
Sbjct: 189 -RLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNV-SAYCLHIAEDDG-EVDTDF 245

Query: 584 PDFDTAE-----GFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTR 632
           P  D+ E     GF T L LV +Y    +  K +          F L Q+  T+
Sbjct: 246 PPLDSNEPIHKFGFST-LALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTK 298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,748,211
Number of Sequences: 37866
Number of extensions: 1372791
Number of successful extensions: 3513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3400
Number of HSP's gapped (non-prelim): 49
length of query: 687
length of database: 18,247,518
effective HSP length: 109
effective length of query: 578
effective length of database: 14,120,124
effective search space: 8161431672
effective search space used: 8161431672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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