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Search of human proteins with 74024917
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens]
(553 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens] 1113 0.0
gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens] 1113 0.0
gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens] 1107 0.0
gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens] 771 0.0
gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens] 761 0.0
gi|45827806 atlastin 3 [Homo sapiens] 681 0.0
gi|14149631 ring finger protein 112 [Homo sapiens] 95 1e-19
gi|38327558 guanylate binding protein 2, interferon-inducible [H... 77 3e-14
gi|31377634 guanylate binding protein 4 [Homo sapiens] 77 5e-14
gi|157671915 guanylate binding protein family, member 6 [Homo sa... 74 3e-13
gi|148234215 guanylate binding protein 4-like [Homo sapiens] 71 2e-12
gi|112382372 guanylate binding protein 3 [Homo sapiens] 69 1e-11
gi|197333737 guanylate-binding protein 5 [Homo sapiens] 68 2e-11
gi|16418425 guanylate-binding protein 5 [Homo sapiens] 68 2e-11
gi|166706903 guanylate binding protein 1, interferon-inducible, ... 66 9e-11
gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens] 35 0.23
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 33 0.52
gi|4504577 indoleamine 2,3-dioxygenase 1 [Homo sapiens] 33 0.68
gi|58761537 hypothetical protein LOC84437 [Homo sapiens] 33 0.89
gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 32 1.5
gi|32455250 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 32 1.5
gi|32455248 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 32 1.5
gi|5031977 nicotinamide phosphoribosyltransferase precursor [Hom... 32 1.5
gi|193083221 mast cell immunoreceptor signal transducer [Homo sa... 31 3.4
gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a ... 30 4.4
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 30 4.4
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 30 5.8
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 30 5.8
gi|25914749 ATP-binding cassette, sub-family C, member 10 [Homo ... 30 5.8
gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens] 29 9.8
>gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens]
Length = 553
Score = 1113 bits (2878), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE 60
MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE
Sbjct: 1 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE 60
Query: 61 AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET 120
AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET
Sbjct: 61 AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET 120
Query: 121 TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ 180
TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ
Sbjct: 121 TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ 180
Query: 181 NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL 240
NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL
Sbjct: 181 NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL 240
Query: 241 KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL 300
KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL
Sbjct: 241 KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL 300
Query: 301 IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV 360
IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV
Sbjct: 301 IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV 360
Query: 361 ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ 420
ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ
Sbjct: 361 ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ 420
Query: 421 LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI 480
LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI
Sbjct: 421 LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI 480
Query: 481 MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTP 540
MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTP
Sbjct: 481 MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTP 540
Query: 541 KSESTEQSEKKKM 553
KSESTEQSEKKKM
Sbjct: 541 KSESTEQSEKKKM 553
>gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens]
Length = 553
Score = 1113 bits (2878), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE 60
MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE
Sbjct: 1 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE 60
Query: 61 AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET 120
AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET
Sbjct: 61 AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET 120
Query: 121 TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ 180
TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ
Sbjct: 121 TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ 180
Query: 181 NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL 240
NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL
Sbjct: 181 NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL 240
Query: 241 KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL 300
KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL
Sbjct: 241 KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL 300
Query: 301 IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV 360
IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV
Sbjct: 301 IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV 360
Query: 361 ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ 420
ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ
Sbjct: 361 ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ 420
Query: 421 LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI 480
LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI
Sbjct: 421 LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI 480
Query: 481 MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTP 540
MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTP
Sbjct: 481 MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTP 540
Query: 541 KSESTEQSEKKKM 553
KSESTEQSEKKKM
Sbjct: 541 KSESTEQSEKKKM 553
>gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens]
Length = 558
Score = 1107 bits (2862), Expect = 0.0
Identities = 553/558 (99%), Positives = 553/558 (99%), Gaps = 5/558 (0%)
Query: 1 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE 60
MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE
Sbjct: 1 MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE 60
Query: 61 AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET 120
AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET
Sbjct: 61 AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERET 120
Query: 121 TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ 180
TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ
Sbjct: 121 TGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ 180
Query: 181 NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL 240
NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL
Sbjct: 181 NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRL 240
Query: 241 KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL 300
KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL
Sbjct: 241 KVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKIL 300
Query: 301 IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV 360
IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV
Sbjct: 301 IPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAV 360
Query: 361 ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ 420
ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ
Sbjct: 361 ATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQ 420
Query: 421 LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI 480
LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI
Sbjct: 421 LESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMI 480
Query: 481 MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQ-----ALYKLYSAAATHRHLYHQ 535
MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQ ALYKLYSAAATHRHLYHQ
Sbjct: 481 MGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYHQ 540
Query: 536 AFPTPKSESTEQSEKKKM 553
AFPTPKSESTEQSEKKKM
Sbjct: 541 AFPTPKSESTEQSEKKKM 558
>gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens]
Length = 579
Score = 771 bits (1990), Expect = 0.0
Identities = 363/528 (68%), Positives = 447/528 (84%), Gaps = 3/528 (0%)
Query: 26 EEPVKKAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLM 84
+E +KK PVQ+++ +DDH+FELDE AL +ILL E +RD +V VSVAGAFRKGKSFL+
Sbjct: 52 DEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLL 111
Query: 85 DFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLL 144
DFMLRYMYN++S W+G NEPLTGF+WRGG ERETTGIQ+W+E+F+I++P+G KVAVLL
Sbjct: 112 DFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLL 171
Query: 145 MDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEET 204
MDTQG FDSQST++D ATVFALSTM SS+QVYNLSQN+QEDDLQHLQLFTEYGRLAMEE
Sbjct: 172 MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEI 231
Query: 205 FLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNI 264
+ KPFQ+L+FL+RDWS+PYE SYG +GG +FLEKRL+V NQHEELQNVRKHIH+CF+N+
Sbjct: 232 YQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNL 291
Query: 265 SCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRG 324
CFLLPHPGLKVATNP+FDG+LK+ID++F + L+ L+P LL+PE+L KEI+G+K+TCR
Sbjct: 292 GCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351
Query: 325 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAP 384
LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVA A+DTY K ME++CGGDKP++AP
Sbjct: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAP 411
Query: 385 NDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHA 444
+DL+ KHL LKE ++K FR VKKMGG+EF RRY QLE+EI+E Y +IKHND KNIF+A
Sbjct: 412 SDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYA 471
Query: 445 ARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELG 504
ARTPATLF V+F Y+I+G+TGFIGL+ IA LCN++MGL LI LCTWAY++YSGE+RE+G
Sbjct: 472 ARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG 531
Query: 505 AVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKK 552
VIDQ+A LW+Q KL+ T R + H+A + + + + KK
Sbjct: 532 TVIDQIAETLWEQVFSKLFE--VTRRRMVHRALSSAQRQRLSSNNNKK 577
>gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens]
Length = 583
Score = 761 bits (1964), Expect = 0.0
Identities = 357/498 (71%), Positives = 434/498 (87%), Gaps = 1/498 (0%)
Query: 26 EEPVKKAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLM 84
+E +KK PVQ+++ +DDH+FELDE AL +ILL E +RD +V VSVAGAFRKGKSFL+
Sbjct: 52 DEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLL 111
Query: 85 DFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLL 144
DFMLRYMYN++S W+G NEPLTGF+WRGG ERETTGIQ+W+E+F+I++P+G KVAVLL
Sbjct: 112 DFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLL 171
Query: 145 MDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEET 204
MDTQG FDSQST++D ATVFALSTM SS+QVYNLSQN+QEDDLQHLQLFTEYGRLAMEE
Sbjct: 172 MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEI 231
Query: 205 FLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNI 264
+ KPFQ+L+FL+RDWS+PYE SYG +GG +FLEKRL+V NQHEELQNVRKHIH+CF+N+
Sbjct: 232 YQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNL 291
Query: 265 SCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRG 324
CFLLPHPGLKVATNP+FDG+LK+ID++F + L+ L+P LL+PE+L KEI+G+K+TCR
Sbjct: 292 GCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351
Query: 325 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAP 384
LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVA A+DTY K ME++CGGDKP++AP
Sbjct: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAP 411
Query: 385 NDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHA 444
+DL+ KHL LKE ++K FR VKKMGG+EF RRY QLE+EI+E Y +IKHND KNIF+A
Sbjct: 412 SDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYA 471
Query: 445 ARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELG 504
ARTPATLF V+F Y+I+G+TGFIGL+ IA LCN++MGL LI LCTWAY++YSGE+RE+G
Sbjct: 472 ARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG 531
Query: 505 AVIDQVAAALWDQALYKL 522
VIDQ+A LW+Q L L
Sbjct: 532 TVIDQIAETLWEQVLKPL 549
>gi|45827806 atlastin 3 [Homo sapiens]
Length = 541
Score = 681 bits (1758), Expect = 0.0
Identities = 329/492 (66%), Positives = 404/492 (82%), Gaps = 4/492 (0%)
Query: 31 KAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLR 89
K GPVQV++V KD HSFELDE AL ILL + +RD +VV VSVAGAFRKGKSF++DFMLR
Sbjct: 23 KPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKSFILDFMLR 82
Query: 90 YMYNQESV---DWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMD 146
Y+Y+Q+ +W+GD EPLTGFSWRGGS+ ETTGIQIWSE+F + KP GKKVAV+LMD
Sbjct: 83 YLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGKKVAVVLMD 142
Query: 147 TQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFL 206
TQG FDSQST++D AT+FALSTM SS+Q+YNLSQN+QEDDLQ LQLFTEYGRLAM+E F
Sbjct: 143 TQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRLAMDEIFQ 202
Query: 207 KPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISC 266
KPFQ+L+FLVRDWSFPYE+SYG GG FL+KRL+V +QHEE+QNVR HIHSCF++++C
Sbjct: 203 KPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIHSCFSDVTC 262
Query: 267 FLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLV 326
FLLPHPGL+VAT+P+FDGKLK+I EF + L+ LIP++L+P L KEING+K+TCRGL+
Sbjct: 263 FLLPHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLL 322
Query: 327 EYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPND 386
EYFKAYIKIYQGE+LPHPKSMLQATAEANNLAA A+AKD Y MEE+CGG+KP+L+P+
Sbjct: 323 EYFKAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGEKPYLSPDI 382
Query: 387 LQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAAR 446
L+ KH + K+ ++ F+ KKMGG++FS RY Q+LE EI ELY + KHN SKN+F R
Sbjct: 383 LEEKHCEFKQLALDHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGSKNVFSTFR 442
Query: 447 TPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAV 506
TPA LF I Y+ +G+TGFIGL+++A L N ++GL LI L TW YIRYSG+YRELG
Sbjct: 443 TPAVLFTGIVALYIASGLTGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSGQYRELGGA 502
Query: 507 IDQVAAALWDQA 518
ID AA + +QA
Sbjct: 503 IDFGAAYVLEQA 514
>gi|14149631 ring finger protein 112 [Homo sapiens]
Length = 632
Score = 95.1 bits (235), Expect = 1e-19
Identities = 83/276 (30%), Positives = 129/276 (46%), Gaps = 26/276 (9%)
Query: 24 EEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFL 83
+E PV+ A P+ ++ + L A+NR L RD V ++V G GKSFL
Sbjct: 127 QETCPVR-AEPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFL 185
Query: 84 MDFMLRYMYNQESVDWVGDYNEP------LTGFSWRGGSERETTGIQIWSEIFLINKPDG 137
++ +L+ + ES G+ P L G W G+ GI +WS FL+ K +G
Sbjct: 186 LNHLLQGLPGLES----GEGGRPRGGEASLQGCRW--GANGLARGIWMWSHPFLLGK-EG 238
Query: 138 KKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYG 197
KKVAV L+DT + + + AL+TM+SS Q+ + SQ +++ DL +L++F
Sbjct: 239 KKVAVFLVDTGDAMSPELSRETRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVA 298
Query: 198 RLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHI 257
+ + + P Q L LVRD S P + G G + +RL + +EL ++
Sbjct: 299 EVMGKHYGMVPIQHLDLLVRDSSHPNKAGQGHVGN---IFQRLSGRYPKVQELLQGKR-- 353
Query: 258 HSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEF 293
C LLP PG + N + DD+F
Sbjct: 354 ------ARCCLLPAPGRR-RMNQGHASPGGDTDDDF 382
>gi|38327558 guanylate binding protein 2, interferon-inducible [Homo
sapiens]
Length = 591
Score = 77.4 bits (189), Expect = 3e-14
Identities = 95/413 (23%), Positives = 175/413 (42%), Gaps = 53/413 (12%)
Query: 48 LDETALNRILLSEAVR-----DKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGD 102
+D T ++ EA++ + VV V++ G +R GKS+LM+ + G
Sbjct: 14 IDNTKGQLVVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKL------------AGK 61
Query: 103 YNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSA 161
N GFS + T GI +W + P + ++L+DT+G D + + +
Sbjct: 62 KN----GFSLGSTVKSHTKGIWMW----CVPHPKKPEHTLVLLDTEGLGDIEKGDNENDS 113
Query: 162 TVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEY----------GRLAMEET--FLKPF 209
+FAL+ ++SS VYN + + + L TE G +++++ F+ F
Sbjct: 114 WIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFF 173
Query: 210 QSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKV---SGNQHEELQNVRKHIHSCFTNISC 266
+ ++ +RD++ E +LE LK+ + + + + R I F C
Sbjct: 174 PAFVWTLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKC 233
Query: 267 FLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGN-KITCRGL 325
F+ P K K +E++ +FI+ + ++LS ++K ++G + L
Sbjct: 234 FVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYILSHS--NVKTLSGGIPVNGPRL 291
Query: 326 VEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPN 385
Y+ +LP ++ + A A+ N AAV A Y ++M G K L
Sbjct: 292 ESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQM-----GQKVQLPTE 346
Query: 386 DLQ---TKHLQLKEESVKLF-RGVKKMGGEEFSRRYLQQLESEIDELYIQYIK 434
LQ H + E++++F + K + F R+ QLE+ D+ Q K
Sbjct: 347 TLQELLDLHRDSEREAIEVFMKNSFKDVDQMFQRKLGAQLEARRDDFCKQNSK 399
>gi|31377634 guanylate binding protein 4 [Homo sapiens]
Length = 640
Score = 76.6 bits (187), Expect = 5e-14
Identities = 88/388 (22%), Positives = 165/388 (42%), Gaps = 51/388 (13%)
Query: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
VV V++ G +R GKS+LM+ + G N GF + ET GI +W
Sbjct: 53 VVVVAIVGLYRTGKSYLMNRL------------AGKRN----GFPLGSTVQSETKGIWMW 96
Query: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
L +KP+ ++L+DT+G D +S ++ + +FAL+ ++SS VYN +
Sbjct: 97 CVPHL-SKPNH---TLVLLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQ 152
Query: 186 DLQHLQLFTEYGRLAMEETFLKP------------FQSLIFLVRDWSFPYEFSYGADGGA 233
L+ L TE L ++ +P F I+ VRD++ +
Sbjct: 153 ALEQLHYVTELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITED 212
Query: 234 KFLEKRLKVSGNQHEELQN---VRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEID 290
++LE LK+ ++ ++QN R+ I F CF+ P + + + E+
Sbjct: 213 EYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRP----TNDKQYLNHMDEVP 268
Query: 291 DE-----FIKNLKILIPWLLS-PESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHP 344
+E F+ ++ + ++ ++E G +T + L Y+ +P
Sbjct: 269 EENLERHFLMQSDNFCSYIFTHAKTKTLRE--GIIVTGKRLGTLVVTYVDAINSGAVPCL 326
Query: 345 KSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRG 404
++ + A A+ N AAV A D Y+++M + P +L H + E++ +F
Sbjct: 327 ENAVTALAQLENPAAVQRAADHYSQQMAQQL--RLPTDTLQELLDVHAACEREAIAVFME 384
Query: 405 VK-KMGGEEFSRRYLQQLESEIDELYIQ 431
K EF ++ + +E + + +Q
Sbjct: 385 HSFKDENHEFQKKLVDTIEKKKGDFVLQ 412
>gi|157671915 guanylate binding protein family, member 6 [Homo
sapiens]
Length = 633
Score = 73.9 bits (180), Expect = 3e-13
Identities = 80/384 (20%), Positives = 158/384 (41%), Gaps = 43/384 (11%)
Query: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
VV V++ G +R GKS+LM+ + + GF + ET GI +W
Sbjct: 38 VVVVAIVGLYRTGKSYLMNHLAGQNH----------------GFPLGSTVQSETKGIWMW 81
Query: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
+ P ++L+DT+G D + ++ + +FAL+ ++ S VYN +
Sbjct: 82 C----VPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQ 137
Query: 186 DLQHLQLFTEYGRLAMEETFLKP------------FQSLIFLVRDWSFPYEFSYGADGGA 233
L+ L TE L ++ +P F ++ VRD++ + +
Sbjct: 138 ALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITED 197
Query: 234 KFLEKRLKVSGNQHEELQN---VRKHIHSCFTNISCFLLPHPGLKVATNPNFDG-KLKEI 289
++LE LK+ + +Q R+ I F CF+ P N + K++
Sbjct: 198 EYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQL 257
Query: 290 DDEFIKNLKILIPWLLS-PESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSML 348
D +F + I ++ + + ++E G +T L Y++ +P ++ +
Sbjct: 258 DPKFQEQTNIFCSYIFTHARTKTLRE--GITVTGNRLGTLAVTYVEAINSGAVPCLENAV 315
Query: 349 QATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVK-K 407
A+ N AAV A D Y+++M + P +L H + E++ +F K
Sbjct: 316 ITLAQRENSAAVQRAADYYSQQMAQRV--KLPTDTLQELLDMHAACEREAIAIFMEHSFK 373
Query: 408 MGGEEFSRRYLQQLESEIDELYIQ 431
+EF +++++ ++ + +Q
Sbjct: 374 DENQEFQKKFMETTMNKKGDFLLQ 397
>gi|148234215 guanylate binding protein 4-like [Homo sapiens]
Length = 638
Score = 71.2 bits (173), Expect = 2e-12
Identities = 83/385 (21%), Positives = 162/385 (42%), Gaps = 45/385 (11%)
Query: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
VV V++ G +R GKS+LM+ + N+ GF + ET GI +W
Sbjct: 38 VVVVAIVGLYRTGKSYLMNKL-------------AGKNK---GFPLGCTVKSETKGIWMW 81
Query: 127 SEIFLINKPDGKKVAVLLMDTQGTFDSQ-STLRDSATVFALSTMISSIQVYNLSQNVQED 185
+ P ++L+DT+G D + S + + +FAL+ ++SS VYN +
Sbjct: 82 C----VPHPSKPNHTLILLDTEGLGDMEKSDPKSDSWIFALAVLLSSSFVYNSMGTINHQ 137
Query: 186 DLQHLQLFTEYGRLAMEETFLKP------------FQSLIFLVRDWSFPYEFSYGADGGA 233
L+ L TE L ++ +P F I+ VRD++ +
Sbjct: 138 ALEQLHYVTELTELIRAKSCPRPDEVEDSSEFVSFFPDFIWTVRDFTLELKLDGHPITED 197
Query: 234 KFLEKRLKVSGNQHEELQN---VRKHIHSCFTNISCFLLPHP--GLKVATNPNFDGKLKE 288
++LE LK+ ++ ++QN R+ I F CF+ P K+ + + + +
Sbjct: 198 EYLENALKLISGKNPQIQNSNKPREWIRHFFPKQKCFVFDRPINDKKLLLHVE-EVREDQ 256
Query: 289 IDDEFIKNLKILIPWLLS-PESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSM 347
+D F + ++ + ++ ++E G +T L + Y+ P ++
Sbjct: 257 LDSNFQMQSENFCSYIFTHAKTKTLRE--GILVTGNRLGMLVETYLDAINSGATPCLENA 314
Query: 348 LQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVK- 406
+ A+ N AAV A + Y+++M + L +L H + E++ +F
Sbjct: 315 MAVLAQCENSAAVQRAANHYSQQMAQQVRFPTDTL--QELLDVHAVCEREAIAVFMEYSF 372
Query: 407 KMGGEEFSRRYLQQLESEIDELYIQ 431
K +EF ++ + +E + ++ +Q
Sbjct: 373 KDKSQEFQKKLVDTMEKKKEDFVLQ 397
>gi|112382372 guanylate binding protein 3 [Homo sapiens]
Length = 595
Score = 68.9 bits (167), Expect = 1e-11
Identities = 88/386 (22%), Positives = 162/386 (41%), Gaps = 68/386 (17%)
Query: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
VV V++ G +R GKS+LM+ + N+ GFS + T GI +W
Sbjct: 38 VVVVAIVGLYRTGKSYLMNKL-------------AGKNK---GFSLGSTVKSHTKGIWMW 81
Query: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
+ P + ++L+DT+G D + ++ + +F L+ ++SS VYN + +
Sbjct: 82 ----CVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNSMGTINQQ 137
Query: 186 DLQHLQLFTEYGRLAMEET------------FLKPFQSLIFLVRDWSFPYEFSYGADGGA 233
+ L TE ++ F+ F ++ +RD+S E ADG
Sbjct: 138 AMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLE----ADGQP 193
Query: 234 ----KFLEKRLKVSGNQHEELQNV---RKHIHSCFTNISCFL--LPHPGLKVATNPNFDG 284
++LE LK++ ++ +N R I F CF+ LP K+A
Sbjct: 194 LTPDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQD 253
Query: 285 KLKEIDDEFIKNLKILIPWLLSPESLDIKEINGN-KITCRGLVEYFKAYIKIYQGEELPH 343
+E+D EF++ + ++ S + K ++G K+ L YI +LP
Sbjct: 254 --EELDPEFVQQVADFCSYIFS--NSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPC 309
Query: 344 PKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFR 403
++ + A A+ N AAV A Y+++M G K +QL E+++
Sbjct: 310 MENAVLALAQIENSAAVQKAIAHYDQQM-----GQK------------VQLPAETLQELL 352
Query: 404 GVKKMGGEEFSRRYLQQLESEIDELY 429
+ ++ E + Y++ ++D L+
Sbjct: 353 DLHRVSEREATEVYMKNSFKDVDHLF 378
>gi|197333737 guanylate-binding protein 5 [Homo sapiens]
Length = 586
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/391 (21%), Positives = 157/391 (40%), Gaps = 52/391 (13%)
Query: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
VV V++ G +R GKS+LM+ + N+ GFS + T GI IW
Sbjct: 38 VVVVAIVGLYRTGKSYLMNKL-------------AGKNK---GFSVASTVQSHTKGIWIW 81
Query: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
+ P+ ++L+DT+G D ++ ++ +FAL+ ++SS VYN + +
Sbjct: 82 ----CVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYNTVNKIDQG 137
Query: 186 DLQHLQLFTE------------YGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGA 233
+ L TE R+ F L++ +RD+ E
Sbjct: 138 AIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPD 197
Query: 234 KFLEKRLKVSGNQHEELQNV---RKHIHSCFTNISCFLLPHPG-----LKVATNPNFDGK 285
++LE L+ + +QN R I F CF+ P ++ T P+
Sbjct: 198 EYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPD---- 253
Query: 286 LKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPK 345
E++ EF++ + ++ S S+ G + L Y+ +LP +
Sbjct: 254 -DELEPEFVQQVTEFCSYIFS-HSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIE 311
Query: 346 SMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGV 405
+ + A A+ N AAV A Y+++M + P +L H + E++++F
Sbjct: 312 NAVLALAQRENSAAVQKAIAHYDQQMGQKV--QLPMETLQELLDLHRTSEREAIEVF--- 366
Query: 406 KKMGGEEFSRRYLQQLESEIDELYIQYIKHN 436
K ++ + + ++LE+ +D K N
Sbjct: 367 MKNSFKDVDQSFQKELETLLDAKQNDICKRN 397
>gi|16418425 guanylate-binding protein 5 [Homo sapiens]
Length = 586
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/391 (21%), Positives = 157/391 (40%), Gaps = 52/391 (13%)
Query: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
VV V++ G +R GKS+LM+ + N+ GFS + T GI IW
Sbjct: 38 VVVVAIVGLYRTGKSYLMNKL-------------AGKNK---GFSVASTVQSHTKGIWIW 81
Query: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
+ P+ ++L+DT+G D ++ ++ +FAL+ ++SS VYN + +
Sbjct: 82 ----CVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYNTVNKIDQG 137
Query: 186 DLQHLQLFTE------------YGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGA 233
+ L TE R+ F L++ +RD+ E
Sbjct: 138 AIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPD 197
Query: 234 KFLEKRLKVSGNQHEELQNV---RKHIHSCFTNISCFLLPHPG-----LKVATNPNFDGK 285
++LE L+ + +QN R I F CF+ P ++ T P+
Sbjct: 198 EYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPD---- 253
Query: 286 LKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPK 345
E++ EF++ + ++ S S+ G + L Y+ +LP +
Sbjct: 254 -DELEPEFVQQVTEFCSYIFS-HSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIE 311
Query: 346 SMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGV 405
+ + A A+ N AAV A Y+++M + P +L H + E++++F
Sbjct: 312 NAVLALAQRENSAAVQKAIAHYDQQMGQKV--QLPMETLQELLDLHRTSEREAIEVF--- 366
Query: 406 KKMGGEEFSRRYLQQLESEIDELYIQYIKHN 436
K ++ + + ++LE+ +D K N
Sbjct: 367 MKNSFKDVDQSFQKELETLLDAKQNDICKRN 397
>gi|166706903 guanylate binding protein 1, interferon-inducible,
67kDa [Homo sapiens]
Length = 592
Score = 65.9 bits (159), Expect = 9e-11
Identities = 88/388 (22%), Positives = 157/388 (40%), Gaps = 58/388 (14%)
Query: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
+V V++ G +R GKS+LM+ + GFS + T GI +W
Sbjct: 38 MVVVAIVGLYRTGKSYLMNKLAGKK----------------KGFSLGSTVQSHTKGIWMW 81
Query: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
+ P ++L+DT+G D + ++ + +FAL+ ++SS VYN + +
Sbjct: 82 C----VPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQ 137
Query: 186 DLQHLQLFTEYGRLAMEET--------------FLKPFQSLIFLVRDWSFPYEFSYGADG 231
+ L TE ++ F+ F ++ +RD+S E ADG
Sbjct: 138 AMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLE----ADG 193
Query: 232 GAKFLEK------RLKVSGNQHEELQNV-RKHIHSCFTNISCFLLPHPGLKVATNPNFDG 284
++ +LK +Q +E N+ R I F CF+ P +
Sbjct: 194 QPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKL 253
Query: 285 KLKEIDDEFIKNLKILIPWLLSPESLDIKEINGN-KITCRGLVEYFKAYIKIYQGEELPH 343
+ +E+D EF++ + ++ S + K ++G ++ L Y+ +LP
Sbjct: 254 QDEELDPEFVQQVADFCSYIFS--NSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPC 311
Query: 344 PKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQ---TKHLQLKEESVK 400
++ + A A+ N AAV A Y ++M G K L LQ H + E+++
Sbjct: 312 MENAVLALAQIENSAAVQKAIAHYEQQM-----GQKVQLPTETLQELLDLHRDSEREAIE 366
Query: 401 LF-RGVKKMGGEEFSRRYLQQLESEIDE 427
+F R K F + QLE + D+
Sbjct: 367 VFIRSSFKDVDHLFQKELAAQLEKKRDD 394
>gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]
Length = 625
Score = 34.7 bits (78), Expect = 0.23
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 227 YGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGK- 285
+ DG + E+RLK + + EELQ+VR + C L LK DG+
Sbjct: 463 HSMDGAKGWFERRLKEAEGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQR 522
Query: 286 -LKEIDDEFIKNLK 298
L++ +K+LK
Sbjct: 523 ILEKKGSAALKDLK 536
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 33.5 bits (75), Expect = 0.52
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
Query: 369 KKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDE 427
K+ ++ D P P D +T+ + KE +L RG ++ EE L++L++E+DE
Sbjct: 43 KRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEE---EEIDEEELERLKAELDE 98
>gi|4504577 indoleamine 2,3-dioxygenase 1 [Homo sapiens]
Length = 403
Score = 33.1 bits (74), Expect = 0.68
Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 16/112 (14%)
Query: 219 WSFPYEFSYGADGGAKFLE--------KRLKVSGNQHEELQNVRKHIHSCFTNISCFLLP 270
W P EF+ G+ G + + ++ G+ + LQ++R+++ N C L
Sbjct: 253 WEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLES 312
Query: 271 HPGLKVATNPNFDGKLKEIDDEFIK--------NLKILIPWLLSPESLDIKE 314
+P ++ D L+E D +K +L+I+ ++L P S KE
Sbjct: 313 NPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKE 364
>gi|58761537 hypothetical protein LOC84437 [Homo sapiens]
Length = 345
Score = 32.7 bits (73), Expect = 0.89
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 9/101 (8%)
Query: 339 EELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEES 398
E L K LQ E L V + K + ++ + G+K L P D++T+ L+L+ E
Sbjct: 248 ERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQ---GEKSMLQPQDIETEKLKLERER 304
Query: 399 VKLFRGVKKMGGEEFSRRYLQ----QLESEIDELYIQYIKH 435
++L + ++ +F LQ +L+ E D L IQ H
Sbjct: 305 LQLEK--DRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGH 343
>gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 2 [Homo sapiens]
Length = 454
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 342 PHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKL 401
P K + +N+ AV YN + +E ++ +Q+K +++
Sbjct: 157 PVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEA 216
Query: 402 FRGVKKMGGEE------FSRRYLQQLESEIDELYIQYIKHNDSK 439
F K+ E+ +S+ Y+++ + E +E IQ I HN K
Sbjct: 217 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDK 260
>gi|32455250 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 3 [Homo sapiens]
Length = 424
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 342 PHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKL 401
P K + +N+ AV YN + +E ++ +Q+K +++
Sbjct: 127 PVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEA 186
Query: 402 FRGVKKMGGEE------FSRRYLQQLESEIDELYIQYIKHNDSK 439
F K+ E+ +S+ Y+++ + E +E IQ I HN K
Sbjct: 187 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDK 230
>gi|32455248 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 1 [Homo sapiens]
Length = 724
Score = 32.0 bits (71), Expect = 1.5
Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 342 PHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKL 401
P K + +N+ AV YN + +E ++ +Q+K +++
Sbjct: 427 PVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEA 486
Query: 402 FRGVKKMGGEE------FSRRYLQQLESEIDELYIQYIKHNDSK 439
F K+ E+ +S+ Y+++ + E +E IQ I HN K
Sbjct: 487 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDK 530
>gi|5031977 nicotinamide phosphoribosyltransferase precursor [Homo
sapiens]
Length = 491
Score = 32.0 bits (71), Expect = 1.5
Identities = 44/209 (21%), Positives = 82/209 (39%), Gaps = 38/209 (18%)
Query: 14 FSEKTYEWSSEEEE---PVK-KAGPVQVLIVKDDHSFELDETALNRILLS---EAVRDKE 66
F+EK + + E+ + P++ KA P +I + + F ++ T L+ E + +
Sbjct: 96 FNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQS 155
Query: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
++VA R+ K L ++L N + +++ L F +RG S +ET GI
Sbjct: 156 WYPITVATNSREQKKILAKYLLETSGNLDGLEY------KLHDFGYRGVSSQETAGIGAS 209
Query: 127 SEIFLINKPDGKKVAVLLMDTQGTFD----------------------SQSTLRDSATVF 164
+ + D L+ GT D + T F
Sbjct: 210 AHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQF 269
Query: 165 A---LSTMISSIQVYNLSQNVQEDDLQHL 190
+ +S + S +YN + + +DL+HL
Sbjct: 270 SSVPVSVVSDSYDIYNACEKIWGEDLRHL 298
>gi|193083221 mast cell immunoreceptor signal transducer [Homo
sapiens]
Length = 428
Score = 30.8 bits (68), Expect = 3.4
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 186 DLQHLQLFT-EYGRLAMEETFLKPFQSLIFLVRDWS 220
D+QH + + EY R A+EE F+K + FLVRD S
Sbjct: 303 DVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCS 338
>gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a
[Homo sapiens]
Length = 1701
Score = 30.4 bits (67), Expect = 4.4
Identities = 13/29 (44%), Positives = 19/29 (65%)
Query: 330 KAYIKIYQGEELPHPKSMLQATAEANNLA 358
+ Y+ QG ELP+PKS+L A + + LA
Sbjct: 695 RCYLASLQGGELPNPKSLLAAASRPSKLA 723
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 30.4 bits (67), Expect = 4.4
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 13/85 (15%)
Query: 334 KIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQ 393
KIYQ EE+P A +E N + Y ++E D+P+L L+
Sbjct: 55 KIYQEEEMPESG----AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWL---------LR 101
Query: 394 LKEESVKLFRGVKKMGGEEFSRRYL 418
+ +S + F+G+KK G E + Y+
Sbjct: 102 VNGKSGRKFKGIKKGGVTENTSYYI 126
>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
Length = 4302
Score = 30.0 bits (66), Expect = 5.8
Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
Query: 10 SWGGFSEK-TYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVV 68
+W F + T+++ +EE P + GP I +D S+ + TA N I A D +V
Sbjct: 1404 AWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGSYLVTVTASNNI---SAANDSALV 1460
Query: 69 AV 70
V
Sbjct: 1461 EV 1462
>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
Length = 4303
Score = 30.0 bits (66), Expect = 5.8
Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
Query: 10 SWGGFSEK-TYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVV 68
+W F + T+++ +EE P + GP I +D S+ + TA N I A D +V
Sbjct: 1404 AWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGSYLVTVTASNNI---SAANDSALV 1460
Query: 69 AV 70
V
Sbjct: 1461 EV 1462
>gi|25914749 ATP-binding cassette, sub-family C, member 10 [Homo
sapiens]
Length = 1464
Score = 30.0 bits (66), Expect = 5.8
Identities = 13/34 (38%), Positives = 22/34 (64%)
Query: 430 IQYIKHNDSKNIFHAARTPATLFVVIFITYVIAG 463
++ IK+ D+ ++ A P + +VIFITYV+ G
Sbjct: 453 LRVIKYLDAACVYLWAALPVVISIVIFITYVLMG 486
>gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens]
Length = 489
Score = 29.3 bits (64), Expect = 9.8
Identities = 24/118 (20%), Positives = 50/118 (42%), Gaps = 12/118 (10%)
Query: 399 VKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFV----- 453
++++ +M G E + L Q E + DE+ Q S N + L V
Sbjct: 169 IRVYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTT 228
Query: 454 ----VIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVI 507
+ IT + + G + + ++A+L + + L+L+ +C YI+ +E ++
Sbjct: 229 EKSKEVCITIFNSSIKGSLWIPVVAALL-LFLVLSLVFIC--FYIKKINPLKEKSIIL 283
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,325,584
Number of Sequences: 37866
Number of extensions: 858464
Number of successful extensions: 2072
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2032
Number of HSP's gapped (non-prelim): 35
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.