Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 72534748
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72534748 translation initiation factor eIF-2B subunit
alpha/beta/delta-like protein isoform 1 [Homo sapiens]
(369 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72534748 translation initiation factor eIF-2B subunit alpha/b... 720 0.0
gi|23943880 translation initiation factor eIF-2B subunit alpha/b... 546 e-155
gi|78000158 eukaryotic translation initiation factor 2B, subunit... 69 7e-12
gi|78000156 eukaryotic translation initiation factor 2B, subunit... 69 7e-12
gi|187607323 eukaryotic translation initiation factor 2B, subuni... 69 7e-12
gi|4503503 eukaryotic translation initiation factor 2B, subunit ... 66 4e-11
gi|7657058 eukaryotic translation initiation factor 2B, subunit ... 60 3e-09
gi|239756539 PREDICTED: hypothetical protein XP_002344929 [Homo ... 30 3.5
gi|239751144 PREDICTED: hypothetical protein XP_002347730 [Homo ... 30 3.5
gi|239745508 PREDICTED: hypothetical protein XP_002343507 [Homo ... 30 3.5
gi|102469037 jun D proto-oncogene [Homo sapiens] 30 4.5
gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens] 29 5.9
gi|8393009 chromosome 11 open reading frame2 [Homo sapiens] 29 7.7
>gi|72534748 translation initiation factor eIF-2B subunit
alpha/beta/delta-like protein isoform 1 [Homo sapiens]
Length = 369
Score = 720 bits (1859), Expect = 0.0
Identities = 369/369 (100%), Positives = 369/369 (100%)
Query: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60
MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA
Sbjct: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60
Query: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120
VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA
Sbjct: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120
Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180
VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT
Sbjct: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180
Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240
ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV
Sbjct: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240
Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300
SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER
Sbjct: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300
Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR 360
PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR
Sbjct: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR 360
Query: 361 DGTLDGPQM 369
DGTLDGPQM
Sbjct: 361 DGTLDGPQM 369
>gi|23943880 translation initiation factor eIF-2B subunit
alpha/beta/delta-like protein isoform 2 [Homo sapiens]
Length = 322
Score = 546 bits (1406), Expect = e-155
Identities = 302/369 (81%), Positives = 307/369 (83%), Gaps = 47/369 (12%)
Query: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60
MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA
Sbjct: 1 MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLA 60
Query: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120
VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA
Sbjct: 61 VELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEA 120
Query: 121 VRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGT 180
VRER E +L ++ H +R P G + GT
Sbjct: 121 VRER--------RETELCEHWE------EHTRQRELPLRGPLG---------------GT 151
Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240
L ETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV
Sbjct: 152 VL------------------ETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 193
Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300
SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER
Sbjct: 194 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 253
Query: 301 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR 360
PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR
Sbjct: 254 PGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSR 313
Query: 361 DGTLDGPQM 369
DGTLDGPQM
Sbjct: 314 DGTLDGPQM 322
>gi|78000158 eukaryotic translation initiation factor 2B, subunit 4
delta isoform 2 [Homo sapiens]
Length = 523
Score = 68.9 bits (167), Expect = 7e-12
Identities = 69/285 (24%), Positives = 130/285 (45%), Gaps = 46/285 (16%)
Query: 75 LVAFVRDKLSFLVTARPTAVNMARAAR----DLADVAAREAEREGATE------EAVRER 124
LV ++ +SFL RP + +M A + ++ V + + E E +E V+E+
Sbjct: 252 LVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEK 311
Query: 125 VICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGV 184
++ + + +R +++ S G V ++ C++ +
Sbjct: 312 IVLAAQAI---------------SRFAYQKI--SNGDVILVYGCSS---------LVSRI 345
Query: 185 IRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVV 244
++ + GR ++RP+ +G R T LV+ +PA+ + + AA+ VS V+
Sbjct: 346 LQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLL--IPAASYVLPEVSKVL 402
Query: 245 VGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQE 304
+GA ++ANG ++VGT QLA+VA+ H +P V + R++T + E +
Sbjct: 403 LGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDD 462
Query: 305 LTDVNGVRIAA------PGIGVWNPAFDVTPHDLITGGIITELGV 343
L G +A + + N +DVTP +L+ +ITELG+
Sbjct: 463 LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELV-DLVITELGM 506
>gi|78000156 eukaryotic translation initiation factor 2B, subunit 4
delta isoform 3 [Homo sapiens]
Length = 522
Score = 68.9 bits (167), Expect = 7e-12
Identities = 69/285 (24%), Positives = 130/285 (45%), Gaps = 46/285 (16%)
Query: 75 LVAFVRDKLSFLVTARPTAVNMARAAR----DLADVAAREAEREGATE------EAVRER 124
LV ++ +SFL RP + +M A + ++ V + + E E +E V+E+
Sbjct: 251 LVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEK 310
Query: 125 VICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGV 184
++ + + +R +++ S G V ++ C++ +
Sbjct: 311 IVLAAQAI---------------SRFAYQKI--SNGDVILVYGCSS---------LVSRI 344
Query: 185 IRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVV 244
++ + GR ++RP+ +G R T LV+ +PA+ + + AA+ VS V+
Sbjct: 345 LQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLL--IPAASYVLPEVSKVL 401
Query: 245 VGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQE 304
+GA ++ANG ++VGT QLA+VA+ H +P V + R++T + E +
Sbjct: 402 LGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDD 461
Query: 305 LTDVNGVRIAA------PGIGVWNPAFDVTPHDLITGGIITELGV 343
L G +A + + N +DVTP +L+ +ITELG+
Sbjct: 462 LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELV-DLVITELGM 505
>gi|187607323 eukaryotic translation initiation factor 2B, subunit 4
delta isoform 1 [Homo sapiens]
Length = 543
Score = 68.9 bits (167), Expect = 7e-12
Identities = 69/285 (24%), Positives = 130/285 (45%), Gaps = 46/285 (16%)
Query: 75 LVAFVRDKLSFLVTARPTAVNMARAAR----DLADVAAREAEREGATE------EAVRER 124
LV ++ +SFL RP + +M A + ++ V + + E E +E V+E+
Sbjct: 272 LVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEK 331
Query: 125 VICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGV 184
++ + + +R +++ S G V ++ C++ +
Sbjct: 332 IVLAAQAI---------------SRFAYQKI--SNGDVILVYGCSS---------LVSRI 365
Query: 185 IRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVV 244
++ + GR ++RP+ +G R T LV+ +PA+ + + AA+ VS V+
Sbjct: 366 LQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLL--IPAASYVLPEVSKVL 422
Query: 245 VGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQE 304
+GA ++ANG ++VGT QLA+VA+ H +P V + R++T + E +
Sbjct: 423 LGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDD 482
Query: 305 LTDVNGVRIAA------PGIGVWNPAFDVTPHDLITGGIITELGV 343
L G +A + + N +DVTP +L+ +ITELG+
Sbjct: 483 LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELV-DLVITELGM 526
>gi|4503503 eukaryotic translation initiation factor 2B, subunit 1
alpha, 26kDa [Homo sapiens]
Length = 305
Score = 66.2 bits (160), Expect = 4e-11
Identities = 80/295 (27%), Positives = 128/295 (43%), Gaps = 23/295 (7%)
Query: 70 PGLAALVAFVRDKLSFLV-----TARPTAVNMARAARDLADVAAREAEREGATEEAVRER 124
P +A+ VA +R L FL T + N+ A L V + A G E +R
Sbjct: 18 PDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGG-ELFLRFI 76
Query: 125 VICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHC---NTGALATAGYG-T 180
+ E D + I L R++ S K+ L H + + T Y
Sbjct: 77 SLASLE---YSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRV 133
Query: 181 ALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGV 240
L V+ + + + + TE++P G ++ A L + +P T++ D+ V M +
Sbjct: 134 VLRVLEAAVAAKKRFSVYVTESQPDLSGKKM-AKALCHLNVPVTVVLDAAVGYIMEKADL 192
Query: 241 SAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEER 300
V+VGA+ VV NG NK+GT Q+A+ AK PFYV A S +RL + ++
Sbjct: 193 --VIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKF-VRLFPLNQ---QDV 246
Query: 301 PGQELTDVNGVRIAAPG--IGVWNPAFDVTPHDLITGGIITELGVFAPEELRTAL 353
P + + +++A G + +P D T LIT + T+LGV P + L
Sbjct: 247 PDKFKYKADTLKVAQTGQDLKEEHPWVDYTAPSLIT-LLFTDLGVLTPSAVSDEL 300
>gi|7657058 eukaryotic translation initiation factor 2B, subunit 2
beta, 39kDa [Homo sapiens]
Length = 351
Score = 60.1 bits (144), Expect = 3e-09
Identities = 48/174 (27%), Positives = 76/174 (43%), Gaps = 5/174 (2%)
Query: 173 LATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVA 232
+ T G+ + + R H E P+ QG + A L I T++TD+ +
Sbjct: 165 IMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIF 223
Query: 233 AAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETG 292
A M+ V+ V++G ++ANG GT+ LA+ AKHH P V AP +
Sbjct: 224 AVMSR--VNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNE 281
Query: 293 KEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAP 346
++ + +E+ I + V P FD P +LIT I+ +G AP
Sbjct: 282 EDSFHKFVAPEEVLPFTEGDILEK-VSVHCPVFDYVPPELIT-LFISNIGGNAP 333
>gi|239756539 PREDICTED: hypothetical protein XP_002344929 [Homo
sapiens]
Length = 223
Score = 30.0 bits (66), Expect = 3.5
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 28 EAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLV 87
+A+ H A +R + + L G + V AG GG G A +++ + + LV
Sbjct: 53 DALARCHDAVSDVRQL------LLLLRGQCWILVGHGAGCGGRGRRA-GEWIQGENAGLV 105
Query: 88 TARPTAVNMARAARDLADVAAREAEREGATEEAVRER 124
T P+A AR+ R+ AD+A+ EGA +EA R +
Sbjct: 106 TRTPSA---ARSERNAADLAS-----EGAAQEAGRRK 134
>gi|239751144 PREDICTED: hypothetical protein XP_002347730 [Homo
sapiens]
Length = 223
Score = 30.0 bits (66), Expect = 3.5
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 28 EAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLV 87
+A+ H A +R + + L G + V AG GG G A +++ + + LV
Sbjct: 53 DALARCHDAVSDVRQL------LLLLRGQCWILVGHGAGCGGRGRRA-GEWIQGENAGLV 105
Query: 88 TARPTAVNMARAARDLADVAAREAEREGATEEAVRER 124
T P+A AR+ R+ AD+A+ EGA +EA R +
Sbjct: 106 TRTPSA---ARSERNAADLAS-----EGAAQEAGRRK 134
>gi|239745508 PREDICTED: hypothetical protein XP_002343507 [Homo
sapiens]
Length = 223
Score = 30.0 bits (66), Expect = 3.5
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 28 EAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLV 87
+A+ H A +R + + L G + V AG GG G A +++ + + LV
Sbjct: 53 DALARCHDAVSDVRQL------LLLLRGQCWILVGHGAGCGGRGRRA-GEWIQGENAGLV 105
Query: 88 TARPTAVNMARAARDLADVAAREAEREGATEEAVRER 124
T P+A AR+ R+ AD+A+ EGA +EA R +
Sbjct: 106 TRTPSA---ARSERNAADLAS-----EGAAQEAGRRK 134
>gi|102469037 jun D proto-oncogene [Homo sapiens]
Length = 347
Score = 29.6 bits (65), Expect = 4.5
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 66 GAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERV 125
GAGG G AA VAF + + F P A+ R A L D + E +
Sbjct: 203 GAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAA-LKDEPQTVPDVPSFGESPPLSPI 261
Query: 126 ICCTEDML--EKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATA 176
T++ + E+ NR + LER++ KV L NT +TA
Sbjct: 262 DMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTA 314
>gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]
Length = 452
Score = 29.3 bits (64), Expect = 5.9
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 6/58 (10%)
Query: 191 LGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGAD 248
LG H C +T Q +L F Q+PA +TDS + A ++H GV + G D
Sbjct: 236 LGYDVHVLCDQTAQEMQ-EKLQNFA----QLPAHRVTDSCIVALLSH-GVEGAIYGVD 287
>gi|8393009 chromosome 11 open reading frame2 [Homo sapiens]
Length = 782
Score = 28.9 bits (63), Expect = 7.7
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 52 ALVGCLS-----LAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARA 99
A +GCL+ LA AG GPGLA L+A V + + A AV++ A
Sbjct: 417 AFLGCLTDVRQALAAPRVAGKEGPGLAELLANVASSILSHIKASLAAVHLFTA 469
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,306,441
Number of Sequences: 37866
Number of extensions: 568516
Number of successful extensions: 1163
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1154
Number of HSP's gapped (non-prelim): 15
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.