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Search of human proteins with 71773329
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71773329 annexin VI isoform 1 [Homo sapiens]
(673 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71773329 annexin VI isoform 1 [Homo sapiens] 1322 0.0
gi|71773415 annexin VI isoform 2 [Homo sapiens] 1306 0.0
gi|4502107 annexin 5 [Homo sapiens] 361 1e-99
gi|4557317 annexin A11 [Homo sapiens] 359 5e-99
gi|22165433 annexin A11 [Homo sapiens] 359 5e-99
gi|22165431 annexin A11 [Homo sapiens] 359 5e-99
gi|4502105 annexin IV [Homo sapiens] 340 2e-93
gi|4826643 annexin A3 [Homo sapiens] 323 2e-88
gi|91823262 annexin A8 [Homo sapiens] 311 1e-84
gi|149588958 annexin A8-like 1 [Homo sapiens] 311 1e-84
gi|91807122 annexin A8L2 [Homo sapiens] 311 2e-84
gi|4809279 annexin VII isoform 2 [Homo sapiens] 301 1e-81
gi|4502111 annexin VII isoform 1 [Homo sapiens] 301 1e-81
gi|4757756 annexin A2 isoform 2 [Homo sapiens] 291 1e-78
gi|50845386 annexin A2 isoform 2 [Homo sapiens] 291 1e-78
gi|50845388 annexin A2 isoform 1 [Homo sapiens] 291 1e-78
gi|209862831 annexin A2 isoform 2 [Homo sapiens] 291 1e-78
gi|51896029 annexin A13 isoform b [Homo sapiens] 282 8e-76
gi|51895795 annexin A13 isoform a [Homo sapiens] 282 8e-76
gi|4502101 annexin I [Homo sapiens] 268 2e-71
gi|48762937 annexin A10 [Homo sapiens] 262 7e-70
gi|145864465 annexin A9 [Homo sapiens] 209 9e-54
gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo ... 105 1e-22
gi|8923458 COMM domain containing 8 [Homo sapiens] 32 1.9
gi|9910362 semaphorin sem2 [Homo sapiens] 32 2.5
gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 31 3.3
gi|153791893 zinc finger, BED-type containing 4 [Homo sapiens] 31 4.3
gi|93102364 SWAP-70 protein [Homo sapiens] 30 5.6
gi|4506339 peroxisomal biogenesis factor 19 isoform a [Homo sapi... 30 5.6
gi|62548864 Rho guanine nucleotide exchange factor 10 [Homo sapi... 30 5.6
>gi|71773329 annexin VI isoform 1 [Homo sapiens]
Length = 673
Score = 1322 bits (3421), Expect = 0.0
Identities = 673/673 (100%), Positives = 673/673 (100%)
Query: 1 MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQ 60
MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQ
Sbjct: 1 MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQ 60
Query: 61 SYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILA 120
SYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILA
Sbjct: 61 SYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILA 120
Query: 121 SRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQD 180
SRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQD
Sbjct: 121 SRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQD 180
Query: 181 VQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEK 240
VQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEK
Sbjct: 181 VQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEK 240
Query: 241 LMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKS 300
LMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKS
Sbjct: 241 LMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKS 300
Query: 301 LYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPA 360
LYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPA
Sbjct: 301 LYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPA 360
Query: 361 NDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSE 420
NDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSE
Sbjct: 361 NDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSE 420
Query: 421 ISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKED 480
ISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKED
Sbjct: 421 ISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKED 480
Query: 481 YHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDK 540
YHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDK
Sbjct: 481 YHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDK 540
Query: 541 TSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNK 600
TSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNK
Sbjct: 541 TSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNK 600
Query: 601 PLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGD 660
PLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGD
Sbjct: 601 PLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGD 660
Query: 661 FLKALLALCGGED 673
FLKALLALCGGED
Sbjct: 661 FLKALLALCGGED 673
>gi|71773415 annexin VI isoform 2 [Homo sapiens]
Length = 667
Score = 1306 bits (3379), Expect = 0.0
Identities = 667/673 (99%), Positives = 667/673 (99%), Gaps = 6/673 (0%)
Query: 1 MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQ 60
MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQ
Sbjct: 1 MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQ 60
Query: 61 SYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILA 120
SYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILA
Sbjct: 61 SYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILA 120
Query: 121 SRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQD 180
SRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQD
Sbjct: 121 SRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQD 180
Query: 181 VQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEK 240
VQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEK
Sbjct: 181 VQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEK 240
Query: 241 LMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKS 300
LMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKS
Sbjct: 241 LMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKS 300
Query: 301 LYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPA 360
LYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPA
Sbjct: 301 LYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPA 360
Query: 361 NDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSE 420
NDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSE
Sbjct: 361 NDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSE 420
Query: 421 ISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKED 480
ISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKED
Sbjct: 421 ISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKED 480
Query: 481 YHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDK 540
YHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQ EIADTPSGDK
Sbjct: 481 YHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQ------EIADTPSGDK 534
Query: 541 TSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNK 600
TSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNK
Sbjct: 535 TSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNK 594
Query: 601 PLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGD 660
PLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGD
Sbjct: 595 PLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGD 654
Query: 661 FLKALLALCGGED 673
FLKALLALCGGED
Sbjct: 655 FLKALLALCGGED 667
>gi|4502107 annexin 5 [Homo sapiens]
Length = 320
Score = 361 bits (927), Expect = 1e-99
Identities = 182/315 (57%), Positives = 234/315 (74%)
Query: 11 RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
RG++ DFPGFD DAE L AMKG G+D+E+IL ++TSRSN QRQE+ ++K+L+G+DL
Sbjct: 6 RGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDL 65
Query: 71 IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130
+ DLK ELTGKFE+LIV LM+P DA E+K A+ G GT+EK L EI+ASRT E++ +
Sbjct: 66 LDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAI 125
Query: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190
Y++ Y LE D++GDTSG++Q+MLVVLLQ R+ D + E V+QD Q L++AGEL
Sbjct: 126 KQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGEL 185
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
KWGTDE +FI I G RS HLR VFD+Y+ +G IE +I E SG+ E+L+LAVVK IR
Sbjct: 186 KWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIR 245
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
S P Y AE L+ AMKG GT D+TLIR+MVSRSE+D+ +IR+ FR + SLYSMIK DTS
Sbjct: 246 SIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTS 305
Query: 311 GEYKKTLLKLSGGDD 325
G+YKK LL L G DD
Sbjct: 306 GDYKKALLLLCGEDD 320
Score = 301 bits (771), Expect = 1e-81
Identities = 156/322 (48%), Positives = 225/322 (69%), Gaps = 7/322 (2%)
Query: 353 LKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRD 412
L+GTV F+ ADA+ LRKAMKGLGTDE++I+ ++T RSN QRQ+I FK+ FGRD
Sbjct: 5 LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRD 64
Query: 413 LMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRA 472
L+ DLKSE++G +LI+ LM P YDA +LK A++GAGT+EK L EI+A+RT E+RA
Sbjct: 65 LLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRA 124
Query: 473 INEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHRE-EGGENLDQAREDAQVAAEILE 531
I + Y+E+Y SLED + DTSG+++R+L+ L +R+ + G + Q +DAQ + E
Sbjct: 125 IKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGE 184
Query: 532 IADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFV 591
+ E +F+TI TRS HLR+VF +++ ++ + +E TI +E SG++ +
Sbjct: 185 LKWGTD------EEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLL 238
Query: 592 AIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQ 651
A+V+S+++ P + A+ LY +MKGAGTD+ TL R+MVSRSEIDL NIR+EF + + SL+
Sbjct: 239 AVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYS 298
Query: 652 AIEGDTSGDFLKALLALCGGED 673
I+GDTSGD+ KALL LCG +D
Sbjct: 299 MIKGDTSGDYKKALLLLCGEDD 320
Score = 117 bits (293), Expect = 3e-26
Identities = 88/317 (27%), Positives = 159/317 (50%), Gaps = 38/317 (11%)
Query: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRST 252
GTDE + +L +RS + + + G+ + ++ EL+G FEKL++A++K R
Sbjct: 32 GTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRL- 90
Query: 253 PEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGE 312
Y A L A+KG GT + L I+ SR+ ++ I++++ +Y SL + DTSG
Sbjct: 91 --YDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGY 148
Query: 313 YKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKAL 372
Y++ L+ L + D P+A ++ + DA+AL
Sbjct: 149 YQRMLVVLLQANRD------PDAG-----------------------IDEAQVEQDAQAL 179
Query: 373 RKAMK-GLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILG 431
+A + GTDE+ I I RS +++ + + G + + E SG+L +L+L
Sbjct: 180 FQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLA 239
Query: 432 LMMP----PAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLED 487
++ PA Y A+ L AM+GAGTD+ LI ++ +R+ ++ I + +++++ SL
Sbjct: 240 VVKSIRSIPA-YLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYS 298
Query: 488 ALSSDTSGHFRRILISL 504
+ DTSG +++ L+ L
Sbjct: 299 MIKGDTSGDYKKALLLL 315
>gi|4557317 annexin A11 [Homo sapiens]
Length = 505
Score = 359 bits (921), Expect = 5e-99
Identities = 182/315 (57%), Positives = 236/315 (74%)
Query: 11 RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
RG+I D PGFDP +DAE L AMKGFG+D++AI+D + SRSN+QRQ++ S+K+ YGKDL
Sbjct: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
Query: 71 IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130
I DLK EL+G FE+ I+ LM+ P D EIK+AI G+GTDE CLIEILASR+NE + +L
Sbjct: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
Query: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190
AYK +++ LE I DTSGHFQ++L+ L QG R+E V L Q+D Q+LY AGE
Sbjct: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGEN 370
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTDE++F +L +RS+ HL VF+EY + TG+ IE SI E+SGD E+ MLAVVKC++
Sbjct: 371 RLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLK 430
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+TP +FAERL KAM+G GT+D TLIRIMVSRSE D+LDIR ++ Y KSLY I DTS
Sbjct: 431 NTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTS 490
Query: 311 GEYKKTLLKLSGGDD 325
G+Y+K LLK+ GG+D
Sbjct: 491 GDYRKILLKICGGND 505
Score = 313 bits (803), Expect = 3e-85
Identities = 163/321 (50%), Positives = 226/321 (70%), Gaps = 7/321 (2%)
Query: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413
+GT+ A F+P DA+ LRKAMKG GTDE IID + RSN QRQQI +FK+ +G+DL
Sbjct: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
Query: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
+ DLKSE+SG+ + IL LM P +D ++K+A++G GTDE LIEILA+R+N IR +
Sbjct: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEG-GENLDQAREDAQVAAEILEI 532
N AYK ++ K+LE+A+ SDTSGHF+R+LISL+ G+R+E ++ A+ DAQ E+
Sbjct: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ---ELYAA 367
Query: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592
+ G E++F +LC+RS HL VF E+ +MT D+E +I +EMSGD+ + +A
Sbjct: 368 GENRLGTD---ESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLA 424
Query: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652
+V+ +KN P FFA++L K+M+GAGT ++TL RIMVSRSE DLL+IR E+ Y KSL+
Sbjct: 425 VVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHD 484
Query: 653 IEGDTSGDFLKALLALCGGED 673
I GDTSGD+ K LL +CGG D
Sbjct: 485 ISGDTSGDYRKILLKICGGND 505
Score = 145 bits (365), Expect = 2e-34
Identities = 101/323 (31%), Positives = 164/323 (50%), Gaps = 40/323 (12%)
Query: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251
+GTDE I LG+RS + + + + GK + ++ ELSG+FEK +LA++K
Sbjct: 216 FGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMK---- 271
Query: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
TP F + +A+KG+GT + LI I+ SRS + ++ ++ +++K+L I++DTS
Sbjct: 272 TPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTS 331
Query: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370
G +++ L+ LS G+ D + AQ DA+
Sbjct: 332 GHFQRLLISLSQGNRDESTNVDMSLAQ-----------------------------RDAQ 362
Query: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLI 429
L A + LGTDE ++ RS + ++ GRD+ + E+SGDL +
Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422
Query: 430 LG----LMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSL 485
L L PA + A++L KAM GAGT ++ LI I+ +R+ ++ I YK Y KSL
Sbjct: 423 LAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSL 481
Query: 486 EDALSSDTSGHFRRILISLATGH 508
+S DTSG +R+IL+ + G+
Sbjct: 482 YHDISGDTSGDYRKILLKICGGN 504
>gi|22165433 annexin A11 [Homo sapiens]
Length = 505
Score = 359 bits (921), Expect = 5e-99
Identities = 182/315 (57%), Positives = 236/315 (74%)
Query: 11 RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
RG+I D PGFDP +DAE L AMKGFG+D++AI+D + SRSN+QRQ++ S+K+ YGKDL
Sbjct: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
Query: 71 IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130
I DLK EL+G FE+ I+ LM+ P D EIK+AI G+GTDE CLIEILASR+NE + +L
Sbjct: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
Query: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190
AYK +++ LE I DTSGHFQ++L+ L QG R+E V L Q+D Q+LY AGE
Sbjct: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGEN 370
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTDE++F +L +RS+ HL VF+EY + TG+ IE SI E+SGD E+ MLAVVKC++
Sbjct: 371 RLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLK 430
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+TP +FAERL KAM+G GT+D TLIRIMVSRSE D+LDIR ++ Y KSLY I DTS
Sbjct: 431 NTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTS 490
Query: 311 GEYKKTLLKLSGGDD 325
G+Y+K LLK+ GG+D
Sbjct: 491 GDYRKILLKICGGND 505
Score = 313 bits (803), Expect = 3e-85
Identities = 163/321 (50%), Positives = 226/321 (70%), Gaps = 7/321 (2%)
Query: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413
+GT+ A F+P DA+ LRKAMKG GTDE IID + RSN QRQQI +FK+ +G+DL
Sbjct: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
Query: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
+ DLKSE+SG+ + IL LM P +D ++K+A++G GTDE LIEILA+R+N IR +
Sbjct: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEG-GENLDQAREDAQVAAEILEI 532
N AYK ++ K+LE+A+ SDTSGHF+R+LISL+ G+R+E ++ A+ DAQ E+
Sbjct: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ---ELYAA 367
Query: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592
+ G E++F +LC+RS HL VF E+ +MT D+E +I +EMSGD+ + +A
Sbjct: 368 GENRLGTD---ESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLA 424
Query: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652
+V+ +KN P FFA++L K+M+GAGT ++TL RIMVSRSE DLL+IR E+ Y KSL+
Sbjct: 425 VVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHD 484
Query: 653 IEGDTSGDFLKALLALCGGED 673
I GDTSGD+ K LL +CGG D
Sbjct: 485 ISGDTSGDYRKILLKICGGND 505
Score = 145 bits (365), Expect = 2e-34
Identities = 101/323 (31%), Positives = 164/323 (50%), Gaps = 40/323 (12%)
Query: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251
+GTDE I LG+RS + + + + GK + ++ ELSG+FEK +LA++K
Sbjct: 216 FGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMK---- 271
Query: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
TP F + +A+KG+GT + LI I+ SRS + ++ ++ +++K+L I++DTS
Sbjct: 272 TPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTS 331
Query: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370
G +++ L+ LS G+ D + AQ DA+
Sbjct: 332 GHFQRLLISLSQGNRDESTNVDMSLAQ-----------------------------RDAQ 362
Query: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLI 429
L A + LGTDE ++ RS + ++ GRD+ + E+SGDL +
Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422
Query: 430 LG----LMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSL 485
L L PA + A++L KAM GAGT ++ LI I+ +R+ ++ I YK Y KSL
Sbjct: 423 LAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSL 481
Query: 486 EDALSSDTSGHFRRILISLATGH 508
+S DTSG +R+IL+ + G+
Sbjct: 482 YHDISGDTSGDYRKILLKICGGN 504
>gi|22165431 annexin A11 [Homo sapiens]
Length = 505
Score = 359 bits (921), Expect = 5e-99
Identities = 182/315 (57%), Positives = 236/315 (74%)
Query: 11 RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
RG+I D PGFDP +DAE L AMKGFG+D++AI+D + SRSN+QRQ++ S+K+ YGKDL
Sbjct: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
Query: 71 IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130
I DLK EL+G FE+ I+ LM+ P D EIK+AI G+GTDE CLIEILASR+NE + +L
Sbjct: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
Query: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190
AYK +++ LE I DTSGHFQ++L+ L QG R+E V L Q+D Q+LY AGE
Sbjct: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGEN 370
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTDE++F +L +RS+ HL VF+EY + TG+ IE SI E+SGD E+ MLAVVKC++
Sbjct: 371 RLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLK 430
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+TP +FAERL KAM+G GT+D TLIRIMVSRSE D+LDIR ++ Y KSLY I DTS
Sbjct: 431 NTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTS 490
Query: 311 GEYKKTLLKLSGGDD 325
G+Y+K LLK+ GG+D
Sbjct: 491 GDYRKILLKICGGND 505
Score = 313 bits (803), Expect = 3e-85
Identities = 163/321 (50%), Positives = 226/321 (70%), Gaps = 7/321 (2%)
Query: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413
+GT+ A F+P DA+ LRKAMKG GTDE IID + RSN QRQQI +FK+ +G+DL
Sbjct: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
Query: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
+ DLKSE+SG+ + IL LM P +D ++K+A++G GTDE LIEILA+R+N IR +
Sbjct: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEG-GENLDQAREDAQVAAEILEI 532
N AYK ++ K+LE+A+ SDTSGHF+R+LISL+ G+R+E ++ A+ DAQ E+
Sbjct: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ---ELYAA 367
Query: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592
+ G E++F +LC+RS HL VF E+ +MT D+E +I +EMSGD+ + +A
Sbjct: 368 GENRLGTD---ESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLA 424
Query: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652
+V+ +KN P FFA++L K+M+GAGT ++TL RIMVSRSE DLL+IR E+ Y KSL+
Sbjct: 425 VVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHD 484
Query: 653 IEGDTSGDFLKALLALCGGED 673
I GDTSGD+ K LL +CGG D
Sbjct: 485 ISGDTSGDYRKILLKICGGND 505
Score = 145 bits (365), Expect = 2e-34
Identities = 101/323 (31%), Positives = 164/323 (50%), Gaps = 40/323 (12%)
Query: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251
+GTDE I LG+RS + + + + GK + ++ ELSG+FEK +LA++K
Sbjct: 216 FGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMK---- 271
Query: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
TP F + +A+KG+GT + LI I+ SRS + ++ ++ +++K+L I++DTS
Sbjct: 272 TPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTS 331
Query: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370
G +++ L+ LS G+ D + AQ DA+
Sbjct: 332 GHFQRLLISLSQGNRDESTNVDMSLAQ-----------------------------RDAQ 362
Query: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLI 429
L A + LGTDE ++ RS + ++ GRD+ + E+SGDL +
Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422
Query: 430 LG----LMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSL 485
L L PA + A++L KAM GAGT ++ LI I+ +R+ ++ I YK Y KSL
Sbjct: 423 LAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSL 481
Query: 486 EDALSSDTSGHFRRILISLATGH 508
+S DTSG +R+IL+ + G+
Sbjct: 482 YHDISGDTSGDYRKILLKICGGN 504
>gi|4502105 annexin IV [Homo sapiens]
Length = 321
Score = 340 bits (873), Expect = 2e-93
Identities = 171/314 (54%), Positives = 228/314 (72%)
Query: 12 GSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLI 71
G++ GF+ +DA+ L AMKG G+D++AI+ ++ R+ QRQE+ +YKS G+DLI
Sbjct: 8 GTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLI 67
Query: 72 ADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLV 131
DLK EL+G FE++IVG+M P D +E++ A+ G GTDE CLIEILASRT E++ ++
Sbjct: 68 DDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRIS 127
Query: 132 AAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELK 191
Y+ Y R LE DI DTS FQ++LV L G R+E + + + LV+QD QDLYEAGE K
Sbjct: 128 QTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKK 187
Query: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251
WGTDE +F+ +L +R++ HL VFDEY + + K IE SI+ E SG FE +LA+VKC+R+
Sbjct: 188 WGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRN 247
Query: 252 TPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSG 311
YFAE+L+K+MKGLGT DNTLIR+MVSR+E+DMLDIR F+ Y KSLYS IK DTSG
Sbjct: 248 KSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSG 307
Query: 312 EYKKTLLKLSGGDD 325
+Y+K LL L GGDD
Sbjct: 308 DYRKVLLVLCGGDD 321
Score = 323 bits (829), Expect = 2e-88
Identities = 168/321 (52%), Positives = 231/321 (71%), Gaps = 9/321 (2%)
Query: 355 GTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLM 414
GTV+ A+ FN DA+ LRKAMKGLGTDED II ++ +R+ QRQ+IR +KS GRDL+
Sbjct: 8 GTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLI 67
Query: 415 TDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 474
DLKSE+SG+ ++I+G+M P YD ++L++AM+GAGTDE LIEILA+RT EIR I+
Sbjct: 68 DDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRIS 127
Query: 475 EAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQA--REDAQVAAEILEI 532
+ Y++ Y +SLED + SDTS F+R+L+SL+ G R+E G LD A R+DAQ ++ E
Sbjct: 128 QTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDE-GNYLDDALVRQDAQ---DLYEA 183
Query: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592
+ G E +F+T+LC+R+ HL VF E+ +++ D+E +IK E SG DA +A
Sbjct: 184 GEKKWGTD---EVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLA 240
Query: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652
IV+ ++NK +FA+KLYKSMKG GTD+ TL R+MVSR+EID+L+IR F Y KSL+
Sbjct: 241 IVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSF 300
Query: 653 IEGDTSGDFLKALLALCGGED 673
I+GDTSGD+ K LL LCGG+D
Sbjct: 301 IKGDTSGDYRKVLLVLCGGDD 321
Score = 127 bits (318), Expect = 4e-29
Identities = 97/333 (29%), Positives = 163/333 (48%), Gaps = 37/333 (11%)
Query: 179 QDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDF 238
+D Q L +A + GTDE I +L R+ + + Y T G+ + ++ ELSG+F
Sbjct: 20 EDAQTLRKAMK-GLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNF 78
Query: 239 EKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYE 298
E++ +V + T Y + L +AMKG GT + LI I+ SR+ ++ I + ++ +Y
Sbjct: 79 EQV---IVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYG 135
Query: 299 KSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVR 358
+SL I++DTS +++ L+ LS G D G + +A VR
Sbjct: 136 RSLEDDIRSDTSFMFQRVLVSLSAGGRD-EGNYLDDA--------------------LVR 174
Query: 359 PANDFNPDADAKALRKA-MKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDL 417
DA+ L +A K GTDE + ++ R+ + +K +D+ +
Sbjct: 175 --------QDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSI 226
Query: 418 KSEISGDLARLILGL---MMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 474
KSE SG +L + M + Y A++L K+M+G GTD+ LI ++ +R ++ I
Sbjct: 227 KSETSGSFEDALLAIVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIR 286
Query: 475 EAYKEDYHKSLEDALSSDTSGHFRRILISLATG 507
+K Y KSL + DTSG +R++L+ L G
Sbjct: 287 AHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGG 319
>gi|4826643 annexin A3 [Homo sapiens]
Length = 323
Score = 323 bits (829), Expect = 2e-88
Identities = 164/316 (51%), Positives = 224/316 (70%)
Query: 10 YRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKD 69
+RG++ D+P F P+ DAEA+ A++G G+D++ ++ I+T RSN QRQ + + Y++ YGK+
Sbjct: 8 HRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKE 67
Query: 70 LIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQ 129
L DLK +L+G FE L+V L+ PPA DAK++K ++ G GT+E LIEIL +RT+ QM
Sbjct: 68 LKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKD 127
Query: 130 LVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGE 189
+ AY Y++ L DI +TSG F+K L+ L G R+E V E L +QD Q LY+AGE
Sbjct: 128 ISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGE 187
Query: 190 LKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCI 249
+WGTDE +F IL RS L+L FDEY + K I SI+GELSG FE L+LA+V C+
Sbjct: 188 NRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCV 247
Query: 250 RSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDT 309
R+TP + AERL +A+KG+GT + TL RIMVSRSE+D+LDIR F+ Y SLYS IK+DT
Sbjct: 248 RNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDT 307
Query: 310 SGEYKKTLLKLSGGDD 325
SG+Y+ TLLK+ GGDD
Sbjct: 308 SGDYEITLLKICGGDD 323
Score = 293 bits (751), Expect = 3e-79
Identities = 156/323 (48%), Positives = 225/323 (69%), Gaps = 11/323 (3%)
Query: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413
+GTVR DF+P DA+A++KA++G+GTDE +I I+T RSN QRQ I + +++ +G++L
Sbjct: 9 RGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKEL 68
Query: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
DLK ++SG L++ L+ PPA +DAKQLKK+M+GAGT+E ALIEIL TRT+ +++ I
Sbjct: 69 KDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDI 128
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEG---GENLDQAREDAQVAAEIL 530
++AY Y KSL D +SS+TSG FR+ L++LA G R+E E+L A++DAQ+ +
Sbjct: 129 SQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHL--AKQDAQI---LY 183
Query: 531 EIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAF 590
+ + G E +F ILC RS+P L+ F E+ ++ D+ +IK E+SG D
Sbjct: 184 KAGENRWGTD---EDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLL 240
Query: 591 VAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLH 650
+AIV V+N P F A++L++++KG GTDE TL RIMVSRSEIDLL+IR EF + Y SL+
Sbjct: 241 LAIVNCVRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLY 300
Query: 651 QAIEGDTSGDFLKALLALCGGED 673
AI+ DTSGD+ LL +CGG+D
Sbjct: 301 SAIKSDTSGDYEITLLKICGGDD 323
Score = 147 bits (371), Expect = 3e-35
Identities = 104/320 (32%), Positives = 167/320 (52%), Gaps = 38/320 (11%)
Query: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRST 252
GTDE I IL RS +L+ EY GK ++ ++G+LSG FE LM+A+V +
Sbjct: 35 GTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHLMVALV----TP 90
Query: 253 PEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSG 311
P F A++L K+MKG GT ++ LI I+ +R+ M DI + + T Y+KSL I ++TSG
Sbjct: 91 PAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDISSETSG 150
Query: 312 EYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKA 371
+++K LL L+ G D E+ +V ++ DA+
Sbjct: 151 DFRKALLTLADGRRD-------ESLKV----------------------DEHLAKQDAQI 181
Query: 372 LRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISG---DLAR 427
L KA + GTDED +I+ RS Q + +++ +D++ +K E+SG DL
Sbjct: 182 LYKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLL 241
Query: 428 LILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLED 487
I+ + + A++L +A++G GTDE L I+ +R+ ++ I +K+ Y SL
Sbjct: 242 AIVNCVRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYS 301
Query: 488 ALSSDTSGHFRRILISLATG 507
A+ SDTSG + L+ + G
Sbjct: 302 AIKSDTSGDYEITLLKICGG 321
>gi|91823262 annexin A8 [Homo sapiens]
Length = 327
Score = 311 bits (798), Expect = 1e-84
Identities = 168/320 (52%), Positives = 218/320 (68%), Gaps = 5/320 (1%)
Query: 6 QGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSL 65
+G + S H F+P+ DAE LY AMKG G++++AI+D++T RSN QRQ++ +S+K+
Sbjct: 11 EGVTVKSSSH----FNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQ 66
Query: 66 YGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNE 125
+GKDL LK EL+GKFERLIV LM PP +AKE+ DA+ G+GT E +IEILASRT
Sbjct: 67 FGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKN 126
Query: 126 QMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREE-DDVVSEDLVQQDVQDL 184
Q+ +++ AY++ Y LE DI DTSG+ +++LV LLQG+R++ V L QD QDL
Sbjct: 127 QLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDL 186
Query: 185 YEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLA 244
Y AGE GTDE +FI IL RS HL VF+EY K K IE SI+ E G E+ ML
Sbjct: 187 YAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLT 246
Query: 245 VVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSM 304
VVKC ++ YFAERL+ AMKG GTRD TLIR +VSRSE+D+ I+ F+ Y K+L SM
Sbjct: 247 VVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSM 306
Query: 305 IKNDTSGEYKKTLLKLSGGD 324
I DTSG+YK LL L G D
Sbjct: 307 IMEDTSGDYKNALLSLVGSD 326
Score = 283 bits (724), Expect = 4e-76
Identities = 155/328 (47%), Positives = 215/328 (65%), Gaps = 15/328 (4%)
Query: 351 VELKG-TVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHF 409
+E +G TV+ ++ FNPD DA+ L KAMKG+GT+E IID++T RSN QRQQI ++FK+ F
Sbjct: 8 IEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQF 67
Query: 410 GRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAE 469
G+DL LKSE+SG RLI+ LM PP Y+AK+L AM+G GT E +IEILA+RT +
Sbjct: 68 GKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQ 127
Query: 470 IRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLD-----QAREDAQ 524
+R I +AY+EDY SLE+ + +DTSG+ RIL+ L G R++ +D Q +D
Sbjct: 128 LREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLY 187
Query: 525 VAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSG 584
A E + D E +F+TILCTRS HL RVF+E+ K+ N +E +IK E G
Sbjct: 188 AAGEKIRGTD---------EMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHG 238
Query: 585 DVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEK 644
+ +A + +V+ +N +FA++LY +MKGAGT + TL R +VSRSEIDL I+ F +
Sbjct: 239 SLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKM 298
Query: 645 YDKSLHQAIEGDTSGDFLKALLALCGGE 672
Y K+L I DTSGD+ ALL+L G +
Sbjct: 299 YGKTLSSMIMEDTSGDYKNALLSLVGSD 326
Score = 117 bits (294), Expect = 3e-26
Identities = 91/328 (27%), Positives = 155/328 (47%), Gaps = 34/328 (10%)
Query: 180 DVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFE 239
D + LY+A + GT+E I +L RS + + + GK + +++ ELSG FE
Sbjct: 26 DAETLYKAMK-GIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFE 84
Query: 240 KLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEK 299
+L++A++ Y A+ L AMKGLGT++ +I I+ SR++ + +I + + Y
Sbjct: 85 RLIVALMY---PPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGS 141
Query: 300 SLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRP 359
SL I+ DTSG ++ L+ L G D F V P
Sbjct: 142 SLEEDIQADTSGYLERILVCLLQGSRDDVSSF-------------------------VDP 176
Query: 360 ANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKS 419
D A + ++ GTDE I I+ RS ++ + ++ + + +KS
Sbjct: 177 GLALQDAQDLYAAGEKIR--GTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKS 234
Query: 420 EISGDLARLILGLMMPPAH---YDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEA 476
E G L +L ++ + Y A++L AM+GAGT + LI + +R+ ++ I
Sbjct: 235 ETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCH 294
Query: 477 YKEDYHKSLEDALSSDTSGHFRRILISL 504
+K+ Y K+L + DTSG ++ L+SL
Sbjct: 295 FKKMYGKTLSSMIMEDTSGDYKNALLSL 322
>gi|149588958 annexin A8-like 1 [Homo sapiens]
Length = 327
Score = 311 bits (798), Expect = 1e-84
Identities = 168/320 (52%), Positives = 218/320 (68%), Gaps = 5/320 (1%)
Query: 6 QGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSL 65
+G + S H F+P+ DAE LY AMKG G++++AI+D++T RSN QRQ++ +S+K+
Sbjct: 11 EGVTVKSSSH----FNPDPDAETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQ 66
Query: 66 YGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNE 125
+GKDL LK EL+GKFERLIV LM PP +AKE+ DA+ G+GT E +IEILASRT
Sbjct: 67 FGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKN 126
Query: 126 QMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREE-DDVVSEDLVQQDVQDL 184
Q+ +++ AY++ Y LE DI DTSG+ +++LV LLQG+R++ V L QD QDL
Sbjct: 127 QLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDL 186
Query: 185 YEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLA 244
Y AGE GTDE +FI IL RS HL VF+EY K K IE SI+ E G E+ ML
Sbjct: 187 YAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLT 246
Query: 245 VVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSM 304
VVKC ++ YFAERL+ AMKG GTRD TLIR +VSRSE+D+ I+ F+ Y K+L SM
Sbjct: 247 VVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSM 306
Query: 305 IKNDTSGEYKKTLLKLSGGD 324
I DTSG+YK LL L G D
Sbjct: 307 IMEDTSGDYKNALLSLVGSD 326
Score = 281 bits (720), Expect = 1e-75
Identities = 154/328 (46%), Positives = 215/328 (65%), Gaps = 15/328 (4%)
Query: 351 VELKG-TVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHF 409
+E +G TV+ ++ FNPD DA+ L +AMKG+GT+E IID++T RSN QRQQI ++FK+ F
Sbjct: 8 IEQEGVTVKSSSHFNPDPDAETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQF 67
Query: 410 GRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAE 469
G+DL LKSE+SG RLI+ LM PP Y+AK+L AM+G GT E +IEILA+RT +
Sbjct: 68 GKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQ 127
Query: 470 IRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLD-----QAREDAQ 524
+R I +AY+EDY SLE+ + +DTSG+ RIL+ L G R++ +D Q +D
Sbjct: 128 LREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLY 187
Query: 525 VAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSG 584
A E + D E +F+TILCTRS HL RVF+E+ K+ N +E +IK E G
Sbjct: 188 AAGEKIRGTD---------EMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHG 238
Query: 585 DVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEK 644
+ +A + +V+ +N +FA++LY +MKGAGT + TL R +VSRSEIDL I+ F +
Sbjct: 239 SLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKM 298
Query: 645 YDKSLHQAIEGDTSGDFLKALLALCGGE 672
Y K+L I DTSGD+ ALL+L G +
Sbjct: 299 YGKTLSSMIMEDTSGDYKNALLSLVGSD 326
Score = 118 bits (295), Expect = 2e-26
Identities = 91/328 (27%), Positives = 155/328 (47%), Gaps = 34/328 (10%)
Query: 180 DVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFE 239
D + LY+A + GT+E I +L RS + + + GK + +++ ELSG FE
Sbjct: 26 DAETLYQAMK-GIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFE 84
Query: 240 KLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEK 299
+L++A++ Y A+ L AMKGLGT++ +I I+ SR++ + +I + + Y
Sbjct: 85 RLIVALMY---PPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGS 141
Query: 300 SLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRP 359
SL I+ DTSG ++ L+ L G D F V P
Sbjct: 142 SLEEDIQADTSGYLERILVCLLQGSRDDVSSF-------------------------VDP 176
Query: 360 ANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKS 419
D A + ++ GTDE I I+ RS ++ + ++ + + +KS
Sbjct: 177 GLALQDAQDLYAAGEKIR--GTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKS 234
Query: 420 EISGDLARLILGLMMPPAH---YDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEA 476
E G L +L ++ + Y A++L AM+GAGT + LI + +R+ ++ I
Sbjct: 235 ETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCH 294
Query: 477 YKEDYHKSLEDALSSDTSGHFRRILISL 504
+K+ Y K+L + DTSG ++ L+SL
Sbjct: 295 FKKMYGKTLSSMIMEDTSGDYKNALLSL 322
>gi|91807122 annexin A8L2 [Homo sapiens]
Length = 327
Score = 311 bits (796), Expect = 2e-84
Identities = 168/320 (52%), Positives = 218/320 (68%), Gaps = 5/320 (1%)
Query: 6 QGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSL 65
+G + S H F+P+ DAE LY AMKG G++++AI+D++T RSN QRQ++ +S+K+
Sbjct: 11 EGVTVKSSSH----FNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQ 66
Query: 66 YGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNE 125
+GKDL LK EL+GKFERLIV LM PP +AKE+ DA+ G+GT E +IEILASRT
Sbjct: 67 FGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKN 126
Query: 126 QMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREE-DDVVSEDLVQQDVQDL 184
Q+ +++ AY++ Y LE DI DTSG+ +++LV LLQG+R++ V L QD QDL
Sbjct: 127 QLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDL 186
Query: 185 YEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLA 244
Y AGE GTDE +FI IL RS HL VF+EY K K IE SI+ E G E+ ML
Sbjct: 187 YAAGENIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLT 246
Query: 245 VVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSM 304
VVKC ++ YFAERL+ AMKG GTRD TLIR +VSRSE+D+ I+ F+ Y K+L SM
Sbjct: 247 VVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSM 306
Query: 305 IKNDTSGEYKKTLLKLSGGD 324
I DTSG+YK LL L G D
Sbjct: 307 IMEDTSGDYKNALLSLVGSD 326
Score = 283 bits (725), Expect = 3e-76
Identities = 156/330 (47%), Positives = 216/330 (65%), Gaps = 15/330 (4%)
Query: 349 ARVELKG-TVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKS 407
A +E +G TV+ ++ FNPD DA+ L KAMKG+GT+E IID++T RSN QRQQI ++FK+
Sbjct: 6 AWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKA 65
Query: 408 HFGRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTN 467
FG+DL LKSE+SG RLI+ LM PP Y+AK+L AM+G GT E +IEILA+RT
Sbjct: 66 QFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTK 125
Query: 468 AEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLD-----QARED 522
++R I +AY+EDY SLE+ + +DTSG+ RIL+ L G R++ +D Q +D
Sbjct: 126 NQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQD 185
Query: 523 AQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEM 582
A E + D E +F+TILCTRS HL RVF+E+ K+ N +E +IK E
Sbjct: 186 LYAAGENIRGTD---------EMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSET 236
Query: 583 SGDVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFI 642
G + +A + +V+ +N +FA++LY +MKGAGT + TL R +VSRSEIDL I+ F
Sbjct: 237 HGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFK 296
Query: 643 EKYDKSLHQAIEGDTSGDFLKALLALCGGE 672
+ Y K+L I DTSGD+ ALL+L G +
Sbjct: 297 KMYGKTLSSMIMEDTSGDYKNALLSLVGSD 326
Score = 119 bits (298), Expect = 9e-27
Identities = 92/329 (27%), Positives = 157/329 (47%), Gaps = 36/329 (10%)
Query: 180 DVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFE 239
D + LY+A + GT+E I +L RS + + + GK + +++ ELSG FE
Sbjct: 26 DAETLYKAMK-GIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFE 84
Query: 240 KLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEK 299
+L++A++ Y A+ L AMKGLGT++ +I I+ SR++ + +I + + Y
Sbjct: 85 RLIVALMY---PPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGS 141
Query: 300 SLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRP 359
SL I+ DTSG ++ L+ L G D F A +
Sbjct: 142 SLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALAL--------------------- 180
Query: 360 ANDFNPDADAKALRKAMKGL-GTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLK 418
DA+ L A + + GTDE I I+ RS ++ + ++ + + +K
Sbjct: 181 -------QDAQDLYAAGENIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIK 233
Query: 419 SEISGDLARLILGLMMPPAH---YDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINE 475
SE G L +L ++ + Y A++L AM+GAGT + LI + +R+ ++ I
Sbjct: 234 SETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKC 293
Query: 476 AYKEDYHKSLEDALSSDTSGHFRRILISL 504
+K+ Y K+L + DTSG ++ L+SL
Sbjct: 294 HFKKMYGKTLSSMIMEDTSGDYKNALLSL 322
>gi|4809279 annexin VII isoform 2 [Homo sapiens]
Length = 488
Score = 301 bits (772), Expect = 1e-81
Identities = 155/318 (48%), Positives = 215/318 (67%), Gaps = 7/318 (2%)
Query: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413
+GT+RPA +F+ DA+ LRKAMKG GTDE I+D++ +RSN QRQ+I+ FK+ +G+DL
Sbjct: 176 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
Query: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
+ DLKSE+SG++ LIL L MPP +YDA L+KAM+GAGT E+ LIEIL TRTN EIR I
Sbjct: 236 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQVAAEILEI 532
Y+ ++ + LE + SDTSGHF R+L+S+ G+R+E N A+EDAQ +
Sbjct: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQ------RL 349
Query: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592
G + E+ F IL TRS+P LR + + +M N D+ ++ +E SG V
Sbjct: 350 YQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKT 409
Query: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652
I+Q N+P FFA++LY +MKGAGTD+ TL RI+V+RSEIDL+ I++ F + Y K+L
Sbjct: 410 ILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTM 469
Query: 653 IEGDTSGDFLKALLALCG 670
I GDTSGD+ + LLA+ G
Sbjct: 470 IAGDTSGDYRRLLLAIVG 487
Score = 292 bits (747), Expect = 8e-79
Identities = 142/312 (45%), Positives = 214/312 (68%)
Query: 11 RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
+G+I FD +DAE L AMKGFG+D++AI+D++ +RSN QRQ++ ++K+ YGKDL
Sbjct: 176 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
Query: 71 IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130
I DLK EL+G E LI+ L PP Y DA ++ A+ G GT E+ LIEIL +RTN+++ ++
Sbjct: 236 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
Query: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190
V Y+ + RDLE DI DTSGHF+++LV + QG R+E+ ++ + Q+D Q LY+AGE
Sbjct: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEG 355
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTDE+ F IL RS LR + Y + + + +S+ E SG E + +++C
Sbjct: 356 RLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCAL 415
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+ P +FAERL+ AMKG GT D+TL+RI+V+RSE+D++ I+++F Y+K+L +MI DTS
Sbjct: 416 NRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTS 475
Query: 311 GEYKKTLLKLSG 322
G+Y++ LL + G
Sbjct: 476 GDYRRLLLAIVG 487
Score = 132 bits (331), Expect = 1e-30
Identities = 90/318 (28%), Positives = 165/318 (51%), Gaps = 38/318 (11%)
Query: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251
+GTDE + ++ NRS + + + + GK + ++ ELSG+ E+L+LA+
Sbjct: 201 FGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFM---- 256
Query: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
P Y+ A L KAM+G GT++ LI I+ +R+ ++ +I +++++ + L I++DTS
Sbjct: 257 PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTS 316
Query: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370
G +++ L+ + G+ D E + +QM DA+
Sbjct: 317 GHFERLLVSMCQGNRD-------ENQSINHQM----------------------AQEDAQ 347
Query: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL---A 426
L +A +G LGTDE I+ RS Q + + + RDL++ + E SG +
Sbjct: 348 RLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGL 407
Query: 427 RLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLE 486
+ IL + + A++L AM+GAGTD+ L+ I+ TR+ ++ I + + + Y K+L
Sbjct: 408 KTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLG 467
Query: 487 DALSSDTSGHFRRILISL 504
++ DTSG +RR+L+++
Sbjct: 468 TMIAGDTSGDYRRLLLAI 485
Score = 60.8 bits (146), Expect = 4e-09
Identities = 44/154 (28%), Positives = 77/154 (50%), Gaps = 8/154 (5%)
Query: 519 AREDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTI 578
A DA AEIL A G E + ++ RS +++ F D+ +
Sbjct: 183 ANFDAIRDAEILRKAMKGFGTD---EQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDL 239
Query: 579 KKEMSGDVRDAFVAIVQSVKNKPLFF-ADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNI 637
K E+SG++ + +A+ P ++ A L K+M+GAGT E+ L I+ +R+ ++ I
Sbjct: 240 KSELSGNMEELILALFMP----PTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
Query: 638 RREFIEKYDKSLHQAIEGDTSGDFLKALLALCGG 671
R + ++ + L + I DTSG F + L+++C G
Sbjct: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQG 329
>gi|4502111 annexin VII isoform 1 [Homo sapiens]
Length = 466
Score = 301 bits (772), Expect = 1e-81
Identities = 155/318 (48%), Positives = 215/318 (67%), Gaps = 7/318 (2%)
Query: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413
+GT+RPA +F+ DA+ LRKAMKG GTDE I+D++ +RSN QRQ+I+ FK+ +G+DL
Sbjct: 154 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 213
Query: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
+ DLKSE+SG++ LIL L MPP +YDA L+KAM+GAGT E+ LIEIL TRTN EIR I
Sbjct: 214 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 273
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQVAAEILEI 532
Y+ ++ + LE + SDTSGHF R+L+S+ G+R+E N A+EDAQ +
Sbjct: 274 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQ------RL 327
Query: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592
G + E+ F IL TRS+P LR + + +M N D+ ++ +E SG V
Sbjct: 328 YQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKT 387
Query: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652
I+Q N+P FFA++LY +MKGAGTD+ TL RI+V+RSEIDL+ I++ F + Y K+L
Sbjct: 388 ILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTM 447
Query: 653 IEGDTSGDFLKALLALCG 670
I GDTSGD+ + LLA+ G
Sbjct: 448 IAGDTSGDYRRLLLAIVG 465
Score = 292 bits (747), Expect = 8e-79
Identities = 142/312 (45%), Positives = 214/312 (68%)
Query: 11 RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
+G+I FD +DAE L AMKGFG+D++AI+D++ +RSN QRQ++ ++K+ YGKDL
Sbjct: 154 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 213
Query: 71 IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130
I DLK EL+G E LI+ L PP Y DA ++ A+ G GT E+ LIEIL +RTN+++ ++
Sbjct: 214 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 273
Query: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190
V Y+ + RDLE DI DTSGHF+++LV + QG R+E+ ++ + Q+D Q LY+AGE
Sbjct: 274 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEG 333
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTDE+ F IL RS LR + Y + + + +S+ E SG E + +++C
Sbjct: 334 RLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCAL 393
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+ P +FAERL+ AMKG GT D+TL+RI+V+RSE+D++ I+++F Y+K+L +MI DTS
Sbjct: 394 NRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTS 453
Query: 311 GEYKKTLLKLSG 322
G+Y++ LL + G
Sbjct: 454 GDYRRLLLAIVG 465
Score = 132 bits (331), Expect = 1e-30
Identities = 90/318 (28%), Positives = 165/318 (51%), Gaps = 38/318 (11%)
Query: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251
+GTDE + ++ NRS + + + + GK + ++ ELSG+ E+L+LA+
Sbjct: 179 FGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFM---- 234
Query: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
P Y+ A L KAM+G GT++ LI I+ +R+ ++ +I +++++ + L I++DTS
Sbjct: 235 PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTS 294
Query: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370
G +++ L+ + G+ D E + +QM DA+
Sbjct: 295 GHFERLLVSMCQGNRD-------ENQSINHQM----------------------AQEDAQ 325
Query: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL---A 426
L +A +G LGTDE I+ RS Q + + + RDL++ + E SG +
Sbjct: 326 RLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGL 385
Query: 427 RLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLE 486
+ IL + + A++L AM+GAGTD+ L+ I+ TR+ ++ I + + + Y K+L
Sbjct: 386 KTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLG 445
Query: 487 DALSSDTSGHFRRILISL 504
++ DTSG +RR+L+++
Sbjct: 446 TMIAGDTSGDYRRLLLAI 463
Score = 60.8 bits (146), Expect = 4e-09
Identities = 44/154 (28%), Positives = 77/154 (50%), Gaps = 8/154 (5%)
Query: 519 AREDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTI 578
A DA AEIL A G E + ++ RS +++ F D+ +
Sbjct: 161 ANFDAIRDAEILRKAMKGFGTD---EQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDL 217
Query: 579 KKEMSGDVRDAFVAIVQSVKNKPLFF-ADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNI 637
K E+SG++ + +A+ P ++ A L K+M+GAGT E+ L I+ +R+ ++ I
Sbjct: 218 KSELSGNMEELILALFMP----PTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 273
Query: 638 RREFIEKYDKSLHQAIEGDTSGDFLKALLALCGG 671
R + ++ + L + I DTSG F + L+++C G
Sbjct: 274 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQG 307
>gi|4757756 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 291 bits (746), Expect = 1e-78
Identities = 152/315 (48%), Positives = 214/315 (67%), Gaps = 1/315 (0%)
Query: 12 GSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLI 71
GS+ + FD +DA + TA+K G D+ I++I+T+RSN QRQ++ +Y+ K+L
Sbjct: 25 GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELA 84
Query: 72 ADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLV 131
+ LK L+G E +I+GL++ PA DA E+K ++ G+GTDE LIEI+ SRTN+++ ++
Sbjct: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144
Query: 132 AAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREED-DVVSEDLVQQDVQDLYEAGEL 190
YK+ Y+ DLE DII DTSG F+K++V L +G R ED V+ +L+ QD +DLY+AG
Sbjct: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVK 204
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTD ++I I+ RS HL+ VFD Y + + SIR E+ GD E L +V+CI+
Sbjct: 205 RKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQ 264
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+ P YFA+RL+ +MKG GTRD LIRIMVSRSE+DML IR F+ KY KSLY I+ DT
Sbjct: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324
Query: 311 GEYKKTLLKLSGGDD 325
G+Y+K LL L GGDD
Sbjct: 325 GDYQKALLYLCGGDD 339
Score = 283 bits (724), Expect = 4e-76
Identities = 147/319 (46%), Positives = 213/319 (66%), Gaps = 4/319 (1%)
Query: 355 GTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLM 414
G+V+ +F+ + DA + A+K G DE TI++I+T+RSN QRQ I ++ ++L
Sbjct: 25 GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELA 84
Query: 415 TDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 474
+ LKS +SG L +ILGL+ PA YDA +LK +M+G GTDE +LIEI+ +RTN E++ IN
Sbjct: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144
Query: 475 EAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIAD 534
YKE Y LE + SDTSG FR+++++LA G R E G +D D + ++ D
Sbjct: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELID----QDARDLYD 200
Query: 535 TPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 594
K + ++++I+ RS PHL++VF + + YD+ +I+KE+ GD+ +AF+ +V
Sbjct: 201 AGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLV 260
Query: 595 QSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIE 654
Q ++NKPL+FAD+LY SMKG GT +K L RIMVSRSE+D+L IR EF KY KSL+ I+
Sbjct: 261 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ 320
Query: 655 GDTSGDFLKALLALCGGED 673
DT GD+ KALL LCGG+D
Sbjct: 321 QDTKGDYQKALLYLCGGDD 339
>gi|50845386 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 291 bits (746), Expect = 1e-78
Identities = 152/315 (48%), Positives = 214/315 (67%), Gaps = 1/315 (0%)
Query: 12 GSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLI 71
GS+ + FD +DA + TA+K G D+ I++I+T+RSN QRQ++ +Y+ K+L
Sbjct: 25 GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELA 84
Query: 72 ADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLV 131
+ LK L+G E +I+GL++ PA DA E+K ++ G+GTDE LIEI+ SRTN+++ ++
Sbjct: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144
Query: 132 AAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREED-DVVSEDLVQQDVQDLYEAGEL 190
YK+ Y+ DLE DII DTSG F+K++V L +G R ED V+ +L+ QD +DLY+AG
Sbjct: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVK 204
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTD ++I I+ RS HL+ VFD Y + + SIR E+ GD E L +V+CI+
Sbjct: 205 RKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQ 264
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+ P YFA+RL+ +MKG GTRD LIRIMVSRSE+DML IR F+ KY KSLY I+ DT
Sbjct: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324
Query: 311 GEYKKTLLKLSGGDD 325
G+Y+K LL L GGDD
Sbjct: 325 GDYQKALLYLCGGDD 339
Score = 283 bits (724), Expect = 4e-76
Identities = 147/319 (46%), Positives = 213/319 (66%), Gaps = 4/319 (1%)
Query: 355 GTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLM 414
G+V+ +F+ + DA + A+K G DE TI++I+T+RSN QRQ I ++ ++L
Sbjct: 25 GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELA 84
Query: 415 TDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 474
+ LKS +SG L +ILGL+ PA YDA +LK +M+G GTDE +LIEI+ +RTN E++ IN
Sbjct: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144
Query: 475 EAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIAD 534
YKE Y LE + SDTSG FR+++++LA G R E G +D D + ++ D
Sbjct: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELID----QDARDLYD 200
Query: 535 TPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 594
K + ++++I+ RS PHL++VF + + YD+ +I+KE+ GD+ +AF+ +V
Sbjct: 201 AGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLV 260
Query: 595 QSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIE 654
Q ++NKPL+FAD+LY SMKG GT +K L RIMVSRSE+D+L IR EF KY KSL+ I+
Sbjct: 261 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ 320
Query: 655 GDTSGDFLKALLALCGGED 673
DT GD+ KALL LCGG+D
Sbjct: 321 QDTKGDYQKALLYLCGGDD 339
>gi|50845388 annexin A2 isoform 1 [Homo sapiens]
Length = 357
Score = 291 bits (746), Expect = 1e-78
Identities = 152/315 (48%), Positives = 214/315 (67%), Gaps = 1/315 (0%)
Query: 12 GSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLI 71
GS+ + FD +DA + TA+K G D+ I++I+T+RSN QRQ++ +Y+ K+L
Sbjct: 43 GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELA 102
Query: 72 ADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLV 131
+ LK L+G E +I+GL++ PA DA E+K ++ G+GTDE LIEI+ SRTN+++ ++
Sbjct: 103 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 162
Query: 132 AAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREED-DVVSEDLVQQDVQDLYEAGEL 190
YK+ Y+ DLE DII DTSG F+K++V L +G R ED V+ +L+ QD +DLY+AG
Sbjct: 163 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVK 222
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTD ++I I+ RS HL+ VFD Y + + SIR E+ GD E L +V+CI+
Sbjct: 223 RKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQ 282
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+ P YFA+RL+ +MKG GTRD LIRIMVSRSE+DML IR F+ KY KSLY I+ DT
Sbjct: 283 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 342
Query: 311 GEYKKTLLKLSGGDD 325
G+Y+K LL L GGDD
Sbjct: 343 GDYQKALLYLCGGDD 357
Score = 283 bits (724), Expect = 4e-76
Identities = 147/319 (46%), Positives = 213/319 (66%), Gaps = 4/319 (1%)
Query: 355 GTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLM 414
G+V+ +F+ + DA + A+K G DE TI++I+T+RSN QRQ I ++ ++L
Sbjct: 43 GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELA 102
Query: 415 TDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 474
+ LKS +SG L +ILGL+ PA YDA +LK +M+G GTDE +LIEI+ +RTN E++ IN
Sbjct: 103 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 162
Query: 475 EAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIAD 534
YKE Y LE + SDTSG FR+++++LA G R E G +D D + ++ D
Sbjct: 163 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELID----QDARDLYD 218
Query: 535 TPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 594
K + ++++I+ RS PHL++VF + + YD+ +I+KE+ GD+ +AF+ +V
Sbjct: 219 AGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLV 278
Query: 595 QSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIE 654
Q ++NKPL+FAD+LY SMKG GT +K L RIMVSRSE+D+L IR EF KY KSL+ I+
Sbjct: 279 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ 338
Query: 655 GDTSGDFLKALLALCGGED 673
DT GD+ KALL LCGG+D
Sbjct: 339 QDTKGDYQKALLYLCGGDD 357
>gi|209862831 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 291 bits (746), Expect = 1e-78
Identities = 152/315 (48%), Positives = 214/315 (67%), Gaps = 1/315 (0%)
Query: 12 GSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLI 71
GS+ + FD +DA + TA+K G D+ I++I+T+RSN QRQ++ +Y+ K+L
Sbjct: 25 GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELA 84
Query: 72 ADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLV 131
+ LK L+G E +I+GL++ PA DA E+K ++ G+GTDE LIEI+ SRTN+++ ++
Sbjct: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144
Query: 132 AAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREED-DVVSEDLVQQDVQDLYEAGEL 190
YK+ Y+ DLE DII DTSG F+K++V L +G R ED V+ +L+ QD +DLY+AG
Sbjct: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVK 204
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ GTD ++I I+ RS HL+ VFD Y + + SIR E+ GD E L +V+CI+
Sbjct: 205 RKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQ 264
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+ P YFA+RL+ +MKG GTRD LIRIMVSRSE+DML IR F+ KY KSLY I+ DT
Sbjct: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324
Query: 311 GEYKKTLLKLSGGDD 325
G+Y+K LL L GGDD
Sbjct: 325 GDYQKALLYLCGGDD 339
Score = 283 bits (724), Expect = 4e-76
Identities = 147/319 (46%), Positives = 213/319 (66%), Gaps = 4/319 (1%)
Query: 355 GTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLM 414
G+V+ +F+ + DA + A+K G DE TI++I+T+RSN QRQ I ++ ++L
Sbjct: 25 GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELA 84
Query: 415 TDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 474
+ LKS +SG L +ILGL+ PA YDA +LK +M+G GTDE +LIEI+ +RTN E++ IN
Sbjct: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144
Query: 475 EAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIAD 534
YKE Y LE + SDTSG FR+++++LA G R E G +D D + ++ D
Sbjct: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELID----QDARDLYD 200
Query: 535 TPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 594
K + ++++I+ RS PHL++VF + + YD+ +I+KE+ GD+ +AF+ +V
Sbjct: 201 AGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLV 260
Query: 595 QSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIE 654
Q ++NKPL+FAD+LY SMKG GT +K L RIMVSRSE+D+L IR EF KY KSL+ I+
Sbjct: 261 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ 320
Query: 655 GDTSGDFLKALLALCGGED 673
DT GD+ KALL LCGG+D
Sbjct: 321 QDTKGDYQKALLYLCGGDD 339
>gi|51896029 annexin A13 isoform b [Homo sapiens]
Length = 357
Score = 282 bits (721), Expect = 8e-76
Identities = 139/302 (46%), Positives = 211/302 (69%)
Query: 19 GFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYEL 78
GFD ++DA+ L A KG G+++ AI++I++ R++ +RQ++ Q YK+ YGK+L LK EL
Sbjct: 54 GFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSEL 113
Query: 79 TGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAY 138
+G FE+ + L+ P+ A++++ A+ G+GTDE LIE+L +RTN+++ + AY+ +
Sbjct: 114 SGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLF 173
Query: 139 ERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQ 198
+R LE+D+ GDTSG+ +K+LV LLQ R E D V +DL QD +DLY+AGE +WGTDE
Sbjct: 174 DRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELA 233
Query: 199 FIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAE 258
F +L RS + LR F Y GK IE +I E SGD +K L +V+C + +YFAE
Sbjct: 234 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 293
Query: 259 RLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLL 318
RL+K+MKG GT + TLIRI+V+R+E+D+ I+ F+ KY+KSL M+++DTSG+++K L+
Sbjct: 294 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 353
Query: 319 KL 320
L
Sbjct: 354 AL 355
Score = 263 bits (672), Expect = 4e-70
Identities = 141/307 (45%), Positives = 207/307 (67%), Gaps = 7/307 (2%)
Query: 363 FNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEIS 422
F+ D DAK L KA KG+GT+E II+I++ R++ +RQQI+Q +K+ +G++L LKSE+S
Sbjct: 55 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 114
Query: 423 GDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYH 482
G+ + L L+ P+ Y A+QL+KAM+G GTDE LIE+L TRTN EI AI EAY+ +
Sbjct: 115 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
Query: 483 KSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQVAAEILEIADTPSGDKT 541
+SLE + DTSG+ ++IL+SL +R EG + + D A +DA+ ++ D G
Sbjct: 175 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAK------DLYDAGEGRWG 228
Query: 542 SLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKP 601
+ E F +L RSY LR FQ + + D+E I++E SGD++ A++ +V+ ++
Sbjct: 229 TDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCE 288
Query: 602 LFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDF 661
+FA++LYKSMKGAGTDE+TL RI+V+R+E+DL I+ +F EKY KSL + DTSGDF
Sbjct: 289 DYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDF 348
Query: 662 LKALLAL 668
K L+AL
Sbjct: 349 RKLLVAL 355
Score = 120 bits (300), Expect = 5e-27
Identities = 97/361 (26%), Positives = 170/361 (47%), Gaps = 71/361 (19%)
Query: 251 STPEYF-----AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMI 305
S+P+ F A++L KA KG+GT + +I I+ R+ + I++ ++ Y K L ++
Sbjct: 50 SSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVL 109
Query: 306 KNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNP 365
K++ SG ++KT L L + A
Sbjct: 110 KSELSGNFEKTALALLDRPSEYA------------------------------------- 132
Query: 366 DADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL 425
A+ L+KAMKGLGTDE +I+++ R+N + I++ ++ F R L +D+K + SG+L
Sbjct: 133 ---ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNL 189
Query: 426 ARLILGLMMPP-----------AHYDAKQLKKAMEGA-GTDEKALIEILATRTNAEIRAI 473
++++ L+ A DAK L A EG GTDE A E+LA R+ ++RA
Sbjct: 190 KKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRAT 249
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIA 533
+AY+ K +E+A+ +TSG ++ ++L A++ AE +
Sbjct: 250 FQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRC-----------AQDCEDYFAE--RLY 296
Query: 534 DTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAI 593
+ G T ET + I+ TR+ L+ + +F + + ++ + SGD R VA+
Sbjct: 297 KSMKGAGTDEET-LIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
Query: 594 V 594
+
Sbjct: 356 L 356
Score = 100 bits (248), Expect = 6e-21
Identities = 66/234 (28%), Positives = 127/234 (54%), Gaps = 23/234 (9%)
Query: 26 AEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERL 85
A L AMKG G+D+ +++++ +R+N++ + ++Y+ L+ + L +D+K + +G +++
Sbjct: 133 ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 192
Query: 86 IVGLMRPP-----------AYCDAKEIKDAISGI-GTDEKCLIEILASRTNEQMHQLVAA 133
+V L++ A DAK++ DA G GTDE E+LA R+ +Q+ A
Sbjct: 193 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 252
Query: 134 YKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW- 192
Y+ +D+E I +TSG QK + L++ ++ +D +E L + +K
Sbjct: 253 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKS----------MKGA 302
Query: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVV 246
GTDE I I+ R++ L+ + ++ + K + +R + SGDF KL++A++
Sbjct: 303 GTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 356
Score = 84.3 bits (207), Expect = 3e-16
Identities = 47/143 (32%), Positives = 85/143 (59%), Gaps = 4/143 (2%)
Query: 24 QDAEALYTAMKG-FGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKF 82
QDA+ LY A +G +G+D+ A +++ RS +Q + Q+Y+ L GKD+ ++ E +G
Sbjct: 214 QDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDL 273
Query: 83 ERLIVGLMRPPAYCD---AKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYE 139
++ + L+R C+ A+ + ++ G GTDE+ LI I+ +R + + A +++ Y+
Sbjct: 274 QKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 333
Query: 140 RDLEADIIGDTSGHFQKMLVVLL 162
+ L + DTSG F+K+LV LL
Sbjct: 334 KSLSDMVRSDTSGDFRKLLVALL 356
>gi|51895795 annexin A13 isoform a [Homo sapiens]
Length = 316
Score = 282 bits (721), Expect = 8e-76
Identities = 139/302 (46%), Positives = 211/302 (69%)
Query: 19 GFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYEL 78
GFD ++DA+ L A KG G+++ AI++I++ R++ +RQ++ Q YK+ YGK+L LK EL
Sbjct: 13 GFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSEL 72
Query: 79 TGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAY 138
+G FE+ + L+ P+ A++++ A+ G+GTDE LIE+L +RTN+++ + AY+ +
Sbjct: 73 SGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLF 132
Query: 139 ERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQ 198
+R LE+D+ GDTSG+ +K+LV LLQ R E D V +DL QD +DLY+AGE +WGTDE
Sbjct: 133 DRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
Query: 199 FIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAE 258
F +L RS + LR F Y GK IE +I E SGD +K L +V+C + +YFAE
Sbjct: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
Query: 259 RLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLL 318
RL+K+MKG GT + TLIRI+V+R+E+D+ I+ F+ KY+KSL M+++DTSG+++K L+
Sbjct: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
Query: 319 KL 320
L
Sbjct: 313 AL 314
Score = 263 bits (672), Expect = 4e-70
Identities = 141/307 (45%), Positives = 207/307 (67%), Gaps = 7/307 (2%)
Query: 363 FNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEIS 422
F+ D DAK L KA KG+GT+E II+I++ R++ +RQQI+Q +K+ +G++L LKSE+S
Sbjct: 14 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
Query: 423 GDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYH 482
G+ + L L+ P+ Y A+QL+KAM+G GTDE LIE+L TRTN EI AI EAY+ +
Sbjct: 74 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
Query: 483 KSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQVAAEILEIADTPSGDKT 541
+SLE + DTSG+ ++IL+SL +R EG + + D A +DA+ ++ D G
Sbjct: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAK------DLYDAGEGRWG 187
Query: 542 SLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKP 601
+ E F +L RSY LR FQ + + D+E I++E SGD++ A++ +V+ ++
Sbjct: 188 TDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCE 247
Query: 602 LFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDF 661
+FA++LYKSMKGAGTDE+TL RI+V+R+E+DL I+ +F EKY KSL + DTSGDF
Sbjct: 248 DYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDF 307
Query: 662 LKALLAL 668
K L+AL
Sbjct: 308 RKLLVAL 314
Score = 120 bits (300), Expect = 5e-27
Identities = 97/361 (26%), Positives = 170/361 (47%), Gaps = 71/361 (19%)
Query: 251 STPEYF-----AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMI 305
S+P+ F A++L KA KG+GT + +I I+ R+ + I++ ++ Y K L ++
Sbjct: 9 SSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVL 68
Query: 306 KNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNP 365
K++ SG ++KT L L + A
Sbjct: 69 KSELSGNFEKTALALLDRPSEYA------------------------------------- 91
Query: 366 DADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL 425
A+ L+KAMKGLGTDE +I+++ R+N + I++ ++ F R L +D+K + SG+L
Sbjct: 92 ---ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNL 148
Query: 426 ARLILGLMMPP-----------AHYDAKQLKKAMEGA-GTDEKALIEILATRTNAEIRAI 473
++++ L+ A DAK L A EG GTDE A E+LA R+ ++RA
Sbjct: 149 KKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRAT 208
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIA 533
+AY+ K +E+A+ +TSG ++ ++L A++ AE +
Sbjct: 209 FQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRC-----------AQDCEDYFAE--RLY 255
Query: 534 DTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAI 593
+ G T ET + I+ TR+ L+ + +F + + ++ + SGD R VA+
Sbjct: 256 KSMKGAGTDEET-LIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 314
Query: 594 V 594
+
Sbjct: 315 L 315
Score = 100 bits (248), Expect = 6e-21
Identities = 66/234 (28%), Positives = 127/234 (54%), Gaps = 23/234 (9%)
Query: 26 AEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERL 85
A L AMKG G+D+ +++++ +R+N++ + ++Y+ L+ + L +D+K + +G +++
Sbjct: 92 ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 151
Query: 86 IVGLMRPP-----------AYCDAKEIKDAISGI-GTDEKCLIEILASRTNEQMHQLVAA 133
+V L++ A DAK++ DA G GTDE E+LA R+ +Q+ A
Sbjct: 152 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 211
Query: 134 YKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW- 192
Y+ +D+E I +TSG QK + L++ ++ +D +E L + +K
Sbjct: 212 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKS----------MKGA 261
Query: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVV 246
GTDE I I+ R++ L+ + ++ + K + +R + SGDF KL++A++
Sbjct: 262 GTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 315
Score = 84.3 bits (207), Expect = 3e-16
Identities = 47/143 (32%), Positives = 85/143 (59%), Gaps = 4/143 (2%)
Query: 24 QDAEALYTAMKG-FGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKF 82
QDA+ LY A +G +G+D+ A +++ RS +Q + Q+Y+ L GKD+ ++ E +G
Sbjct: 173 QDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDL 232
Query: 83 ERLIVGLMRPPAYCD---AKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYE 139
++ + L+R C+ A+ + ++ G GTDE+ LI I+ +R + + A +++ Y+
Sbjct: 233 QKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 292
Query: 140 RDLEADIIGDTSGHFQKMLVVLL 162
+ L + DTSG F+K+LV LL
Sbjct: 293 KSLSDMVRSDTSGDFRKLLVALL 315
>gi|4502101 annexin I [Homo sapiens]
Length = 346
Score = 268 bits (684), Expect = 2e-71
Identities = 149/316 (47%), Positives = 200/316 (63%), Gaps = 7/316 (2%)
Query: 357 VRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTD 416
V P FNP +D AL KA+ G DE TIIDI+T R+N QRQQI+ + G+ L
Sbjct: 36 VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95
Query: 417 LKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEA 476
LK ++G L ++L L+ PA +DA +L+ AM+G GTDE LIEILA+RTN EIR IN
Sbjct: 96 LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155
Query: 477 YKEDYHKSLEDALSSDTSGHFRRILISLATGHR-EEGGENLDQAREDAQVAAEILEIADT 535
Y+E+ + L ++SDTSG FR L+SLA G R E+ G N D A DA+ + E +
Sbjct: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARA---LYEAGER 212
Query: 536 PSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQ 595
G ++ F TIL TRSYP LRRVFQ++ K + +D+ + E+ GD+ AIV+
Sbjct: 213 RKGTDVNV---FNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVK 269
Query: 596 SVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEG 655
+KP FFA+KL+++MKG GT K L RIMVSRSEID+ +I+ + + Y SL QAI
Sbjct: 270 CATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILD 329
Query: 656 DTSGDFLKALLALCGG 671
+T GD+ K L+ALCGG
Sbjct: 330 ETKGDYEKILVALCGG 345
Score = 262 bits (670), Expect = 7e-70
Identities = 141/312 (45%), Positives = 197/312 (63%)
Query: 13 SIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIA 72
++ +P F+P+ D AL+ A+ G D+ I+DI+T R+N QRQ++ +Y GK L
Sbjct: 35 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94
Query: 73 DLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVA 132
LK LTG E +++ L++ PA DA E++ A+ G+GTDE LIEILASRTN+++ +
Sbjct: 95 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154
Query: 133 AYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW 192
Y++ +RDL DI DTSG F+ L+ L +G R ED V+EDL D + LYEAGE +
Sbjct: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRK 214
Query: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRST 252
GTD F IL RS LR VF +Y K + + + EL GD EK + A+VKC S
Sbjct: 215 GTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSK 274
Query: 253 PEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGE 312
P +FAE+L +AMKG+GTR LIRIMVSRSE+DM DI+ ++ Y SL I ++T G+
Sbjct: 275 PAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGD 334
Query: 313 YKKTLLKLSGGD 324
Y+K L+ L GG+
Sbjct: 335 YEKILVALCGGN 346
Score = 150 bits (378), Expect = 5e-36
Identities = 108/335 (32%), Positives = 181/335 (54%), Gaps = 41/335 (12%)
Query: 180 DVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFE 239
DV L++A +K G DEA I IL R+ + + YL+ TGKP++ +++ L+G E
Sbjct: 47 DVAALHKAIMVK-GVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLE 105
Query: 240 KLMLAVVKCIRSTPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYE 298
+++LA++K TP F A+ L AMKGLGT ++TLI I+ SR+ ++ DI ++R + +
Sbjct: 106 EVVLALLK----TPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161
Query: 299 KSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVR 358
+ L I +DTSG+++ LL L+ GD R E G
Sbjct: 162 RDLAKDITSDTSGDFRNALLSLAKGD-------------------------RSEDFGV-- 194
Query: 359 PANDFNPDADAKALRKA-MKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDL 417
N+ D+DA+AL +A + GTD + I+T RS Q +++ Q + + D+ L
Sbjct: 195 --NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVL 252
Query: 418 KSEISGDLARLILGLMM----PPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
E+ GD+ + + ++ PA + A++L +AM+G GT KALI I+ +R+ ++ I
Sbjct: 253 DLELKGDIEKCLTAIVKCATSKPAFF-AEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDI 311
Query: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGH 508
Y++ Y SL A+ +T G + +IL++L G+
Sbjct: 312 KAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
Score = 77.0 bits (188), Expect = 5e-14
Identities = 43/129 (33%), Positives = 74/129 (57%), Gaps = 3/129 (2%)
Query: 544 ETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLF 603
E + IL R+ +++ +++ T ++ T+KK ++G + + +A++ K F
Sbjct: 62 EATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL---KTPAQF 118
Query: 604 FADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLK 663
AD+L +MKG GTDE TL I+ SR+ ++ +I R + E+ + L + I DTSGDF
Sbjct: 119 DADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRN 178
Query: 664 ALLALCGGE 672
ALL+L G+
Sbjct: 179 ALLSLAKGD 187
>gi|48762937 annexin A10 [Homo sapiens]
Length = 324
Score = 262 bits (670), Expect = 7e-70
Identities = 136/318 (42%), Positives = 204/318 (64%), Gaps = 1/318 (0%)
Query: 7 GAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLY 66
G +G+I P F+P DA+ L A++GF DK+ +++I+T R N QR + ++Y+S+Y
Sbjct: 4 GDYVQGTIFPAPNFNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMY 63
Query: 67 GKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQ 126
G+DLI D++ +L+ F+ ++ GLM PP DA E+ A+ G+GTDE CLIEILASRTN +
Sbjct: 64 GRDLIGDMREQLSDHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGE 123
Query: 127 MHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYE 186
+ Q+ AY Y +L+ DI +TSGHF+ L+ L+QGTREE + QD L+E
Sbjct: 124 IFQMREAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTREE-GYTDPAMAAQDAMVLWE 182
Query: 187 AGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVV 246
A + K G + IL N+S Q LRLVF E+ +G+ + +I G F++L++A+V
Sbjct: 183 ACQQKTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIV 242
Query: 247 KCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIK 306
C+R P YFA RL+ A+ G + T+IRI+++RSE+D+L IR+ ++ +Y KSL+ I+
Sbjct: 243 LCVRDKPAYFAYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIR 302
Query: 307 NDTSGEYKKTLLKLSGGD 324
N SG YKK LL + GD
Sbjct: 303 NFASGHYKKALLAICAGD 320
Score = 251 bits (641), Expect = 2e-66
Identities = 137/320 (42%), Positives = 199/320 (62%), Gaps = 6/320 (1%)
Query: 353 LKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRD 412
++GT+ PA +FNP DA+ L A++G D+D +I+I+T R N QR I + ++S +GRD
Sbjct: 7 VQGTIFPAPNFNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRD 66
Query: 413 LMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRA 472
L+ D++ ++S ++ GLM PP YDA +L AM+G GTDE LIEILA+RTN EI
Sbjct: 67 LIGDMREQLSDHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQ 126
Query: 473 INEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEI 532
+ EAY Y +L++ + S+TSGHFR L++L G REEG + A +DA V + E
Sbjct: 127 MREAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTREEGYTDPAMAAQDAMV---LWEA 183
Query: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592
+G+ +T ILC +SY LR VFQEF ++ D+ I + G ++ VA
Sbjct: 184 CQQKTGEH---KTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVA 240
Query: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652
IV V++KP +FA +LY ++ G KT+ RI+++RSEIDLL IR+ + E+Y KSL
Sbjct: 241 IVLCVRDKPAYFAYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHD 300
Query: 653 IEGDTSGDFLKALLALCGGE 672
I SG + KALLA+C G+
Sbjct: 301 IRNFASGHYKKALLAICAGD 320
Score = 109 bits (273), Expect = 7e-24
Identities = 81/321 (25%), Positives = 148/321 (46%), Gaps = 37/321 (11%)
Query: 195 DEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPE 254
D+ I IL R ++ + Y G+ + +R +LS F+ +M ++ P
Sbjct: 36 DKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFKDVMAGLMY---PPPL 92
Query: 255 YFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYK 314
Y A L+ AMKG+GT +N LI I+ SR+ ++ +RE + +Y +L I ++TSG ++
Sbjct: 93 YDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREAYCLQYSNNLQEDIYSETSGHFR 152
Query: 315 KTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKALRK 374
TL+ L G + AAQ A +WE
Sbjct: 153 DTLMNLVQGTREEGYTDPAMAAQDAMVLWEA----------------------------- 183
Query: 375 AMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMM 434
+ G + + I+ ++S Q + + Q F++ G+D++ + G L++ +++
Sbjct: 184 CQQKTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVL 243
Query: 435 ----PPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALS 490
PA++ A +L A+ G K +I IL R+ ++ I + YKE Y KSL +
Sbjct: 244 CVRDKPAYF-AYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIR 302
Query: 491 SDTSGHFRRILISLATGHREE 511
+ SGH+++ L+++ G E+
Sbjct: 303 NFASGHYKKALLAICAGDAED 323
Score = 60.8 bits (146), Expect = 4e-09
Identities = 43/150 (28%), Positives = 76/150 (50%), Gaps = 6/150 (4%)
Query: 24 QDAEALYTA-MKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKF 82
QDA L+ A + G K + I+ ++S +Q + V Q ++++ G+D++ + G F
Sbjct: 175 QDAMVLWEACQQKTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYF 234
Query: 83 ERLIVGLMR----PPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAY 138
+ L+V ++ PAY A + AI G K +I IL +R+ + + YK+ Y
Sbjct: 235 QELLVAIVLCVRDKPAYF-AYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERY 293
Query: 139 ERDLEADIIGDTSGHFQKMLVVLLQGTREE 168
+ L DI SGH++K L+ + G E+
Sbjct: 294 GKSLFHDIRNFASGHYKKALLAICAGDAED 323
>gi|145864465 annexin A9 [Homo sapiens]
Length = 345
Score = 209 bits (531), Expect = 9e-54
Identities = 112/319 (35%), Positives = 192/319 (60%), Gaps = 7/319 (2%)
Query: 355 GTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLM 414
GT+R +F+ D DA+ L +A+ G G D I+D++T+RS QRQ I + F+ +DLM
Sbjct: 33 GTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLM 92
Query: 415 TDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 474
L++ +SG+L R+++ L+ P A +DA++L+ A++ + + IEILATRT +++
Sbjct: 93 KSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQECL 152
Query: 475 EAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIAD 534
YK ++ D ++S+TSG + +L++LA G R+ +D + V A L+ A+
Sbjct: 153 AVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQA--LQRAE 210
Query: 535 TPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 594
PS ++T ++ + R+ HL RVF ++ + T ++E ++ GD + A + +
Sbjct: 211 GPSREET-----WVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLA 265
Query: 595 QSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIE 654
+KN PL+FADKL+++++ + + L RI++SR E DLL+IR EF +K+ KSL+ +++
Sbjct: 266 SVIKNTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSLQ 325
Query: 655 GDTSGDFLKALLALCGGED 673
GD ALLALC ED
Sbjct: 326 DAVKGDCQSALLALCRAED 344
Score = 199 bits (507), Expect = 5e-51
Identities = 107/315 (33%), Positives = 188/315 (59%), Gaps = 4/315 (1%)
Query: 12 GSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLI 71
G++ F F ++DA+ L A+ G G D+ AI+D++T+RS QRQ + ++++ +DL+
Sbjct: 33 GTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLM 92
Query: 72 ADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLV 131
L+ L+G ER+++ L++P A DA+E++ A+ + IEILA+RT Q+ + +
Sbjct: 93 KSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQECL 152
Query: 132 AAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREE-DDVVSEDLVQQDVQDLYEAGEL 190
A YK ++ + DI +TSG Q +L+ L +G R+ ++ +L +QDVQ L A
Sbjct: 153 AVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQALQRA--- 209
Query: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
+ + E ++ + R+ +HL VFD+Y ++TG+ +E +++ GD + +L + I+
Sbjct: 210 EGPSREETWVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASVIK 269
Query: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
+TP YFA++L +A++ LIRI++SR E D+L IR FR K+ KSLYS +++
Sbjct: 270 NTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSLQDAVK 329
Query: 311 GEYKKTLLKLSGGDD 325
G+ + LL L +D
Sbjct: 330 GDCQSALLALCRAED 344
>gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo
sapiens]
Length = 112
Score = 105 bits (263), Expect = 1e-22
Identities = 59/108 (54%), Positives = 72/108 (66%)
Query: 198 QFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFA 257
+FI IL RS HL VF+EY K K IE SI+ E G E+ ML VVKC ++ YFA
Sbjct: 2 KFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFA 61
Query: 258 ERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMI 305
ERL+ AMKG GTRD TLIR +VSRSE+D+ I+ F+ Y K+L SMI
Sbjct: 62 ERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109
Score = 99.8 bits (247), Expect = 7e-21
Identities = 51/108 (47%), Positives = 73/108 (67%)
Query: 546 RFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFA 605
+F+TILCTRS HL RVF+E+ K+ N +E +IK E G + +A + +V+ +N +FA
Sbjct: 2 KFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFA 61
Query: 606 DKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAI 653
++LY +MKGAGT + TL R +VSRSEIDL I+ F + Y K+L I
Sbjct: 62 ERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109
Score = 40.8 bits (94), Expect = 0.004
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 3/106 (2%)
Query: 387 IDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMMPPAH---YDAKQ 443
I I+ RS ++ + ++ + + +KSE G L +L ++ + Y A++
Sbjct: 4 ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAER 63
Query: 444 LKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDAL 489
L AM+GAGT + LI + +R+ ++ I +K+ Y K+L +
Sbjct: 64 LYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109
Score = 33.9 bits (76), Expect = 0.50
Identities = 32/139 (23%), Positives = 52/139 (37%), Gaps = 37/139 (26%)
Query: 275 IRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPE 334
I I+ +RS +L + E + KS+ IK++T G ++ +L + + F
Sbjct: 4 ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYF--- 60
Query: 335 AAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRS 394
A+ L AMKG GT + T+I I RS
Sbjct: 61 ----------------------------------AERLYYAMKGAGTRDGTLIRNIVSRS 86
Query: 395 NVQRQQIRQTFKSHFGRDL 413
+ I+ FK +G+ L
Sbjct: 87 EIDLNLIKCHFKKMYGKTL 105
Score = 32.7 bits (73), Expect = 1.1
Identities = 14/46 (30%), Positives = 28/46 (60%)
Query: 459 IEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISL 504
I IL TR+ + + E Y++ +KS+ED++ S+T G ++++
Sbjct: 4 ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTV 49
Score = 32.3 bits (72), Expect = 1.5
Identities = 18/45 (40%), Positives = 24/45 (53%)
Query: 26 AEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
AE LY AMKG G+ ++ I SRS + +K +YGK L
Sbjct: 61 AERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTL 105
>gi|8923458 COMM domain containing 8 [Homo sapiens]
Length = 183
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 469 EIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEG---GENLDQAREDAQV 525
EI AI+ A +D+ ++ ALSSD R L+SL +E G +++ +RE+ Q
Sbjct: 108 EIVAISSAQLQDFDWQVKLALSSDKIAALRMPLLSLHLDVKENGEVKPYSIEMSREELQN 167
Query: 526 AAEILEIAD 534
+ LE A+
Sbjct: 168 LIQSLEAAN 176
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 31.6 bits (70), Expect = 2.5
Identities = 15/52 (28%), Positives = 29/52 (55%)
Query: 125 EQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDL 176
+Q+HQ+V +A + + +G SG K++ + G+ E ++VV E+L
Sbjct: 434 QQLHQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQAGGSAEPEEVVLEEL 485
>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
Length = 1014
Score = 31.2 bits (69), Expect = 3.3
Identities = 70/341 (20%), Positives = 123/341 (36%), Gaps = 66/341 (19%)
Query: 173 SEDLVQQDVQDLYEA--GELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASI 230
S+ L ++ + L+E G + D + ++ GN Q +EY K GKP
Sbjct: 296 SKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKP----- 350
Query: 231 RGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIR 290
ML V+ TP Y A + + M+ + + RS LD+
Sbjct: 351 -----------MLEFVE----TPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTP 395
Query: 291 EIFRTKYEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVAR 350
E KY +L EYKK L +++ G+ ++V
Sbjct: 396 EFLHVKYITNLL------REKEYKKDL------ENEIKGKGMELNSEV------------ 431
Query: 351 VELKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFG 410
++++ R + + K L +KG G T ++ Q ++ +
Sbjct: 432 LDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGT--------DTLEMQHAKKAAEIASE 483
Query: 411 RDLMTDLKSEISG----------DLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALI- 459
+D DL++EI G D+ R M K L+ ++G G I
Sbjct: 484 KDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIP 543
Query: 460 EILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRI 500
+IL + +EI + YK++ K L + + + +RI
Sbjct: 544 DILRAKRTSEIYS-QRKYKDEAEKMLSNYSTIADTPEIQRI 583
>gi|153791893 zinc finger, BED-type containing 4 [Homo sapiens]
Length = 1171
Score = 30.8 bits (68), Expect = 4.3
Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 14/102 (13%)
Query: 224 KPIEASIRGELSGDFEKL--MLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSR 281
KP EA+ R E+S L ++ +V + E LF+ G+ T +L MVSR
Sbjct: 938 KPFEAASR-EMSTQMSTLSQVIPMVHILNRK----VEMLFEETMGIDTMLRSLKEAMVSR 992
Query: 282 SELDMLDIREIFRT----KYEKSLYSMIKNDTSGEYKKTLLK 319
+ D R +F T +Y+ SL++ + + +YK+ L++
Sbjct: 993 LSATLHDPRYVFATLLDPRYKASLFT---EEEAEQYKQDLIR 1031
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 30.4 bits (67), Expect = 5.6
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 429 ILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKED---YHKSL 485
+L L PP H +A+Q +K + E+ +E R E++A NE+ +++ K L
Sbjct: 307 LLKLGSPPPHKEARQRRKELRKKQLAEQEELE----RQMKELQAANESKQQELEAVRKKL 362
Query: 486 EDALSSDTSGHFRRILISLATGHR---EEGGENLDQAREDAQVAAEILEI 532
E+A S +R+ + R E E L + + + QVA + E+
Sbjct: 363 EEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSEL 412
>gi|4506339 peroxisomal biogenesis factor 19 isoform a [Homo
sapiens]
Length = 299
Score = 30.4 bits (67), Expect = 5.6
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 7/94 (7%)
Query: 297 YEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQF--FPEAA-QVAYQMW---ELSAVAR 350
+++ S + + + E++K + +L+ + QF EAA +V M E ++ +
Sbjct: 71 FQELFDSELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDMTSQQEFTSCLK 130
Query: 351 VELKGTVRPANDF-NPDADAKALRKAMKGLGTDE 383
L G + A D N + L KAM+GLG DE
Sbjct: 131 ETLSGLAKNATDLQNSSMSEEELTKAMEGLGMDE 164
>gi|62548864 Rho guanine nucleotide exchange factor 10 [Homo
sapiens]
Length = 1344
Score = 30.4 bits (67), Expect = 5.6
Identities = 15/49 (30%), Positives = 26/49 (53%)
Query: 485 LEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIA 533
L+D L + + GH R+ + +A E E L++ + DA E+ +IA
Sbjct: 549 LQDMLKNTSKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIA 597
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,802,107
Number of Sequences: 37866
Number of extensions: 934480
Number of successful extensions: 2742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2226
Number of HSP's gapped (non-prelim): 93
length of query: 673
length of database: 18,247,518
effective HSP length: 109
effective length of query: 564
effective length of database: 14,120,124
effective search space: 7963749936
effective search space used: 7963749936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.