Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 7019419
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019419 guanine nucleotide binding protein-like 2
(nucleolar) [Homo sapiens]
(731 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)... 1457 0.0
gi|9506611 guanine nucleotide binding protein-like 3 (nucleolar)... 179 1e-44
gi|45643129 guanine nucleotide binding protein-like 3 isoform 2 ... 171 2e-42
gi|45643127 guanine nucleotide binding protein-like 3 isoform 2 ... 171 2e-42
gi|45593130 guanine nucleotide binding protein-like 3 isoform 1 ... 171 2e-42
gi|223029424 large subunit GTPase 1 [Homo sapiens] 92 2e-18
gi|38788319 guanine nucleotide binding protein-like 1 [Homo sapi... 80 5e-15
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 56 1e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 54 4e-07
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 54 7e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 53 9e-07
gi|93277113 GTP_binding protein [Homo sapiens] 53 1e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 1e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 52 1e-06
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 51 4e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 51 4e-06
gi|217330641 IWS1 homolog [Homo sapiens] 50 7e-06
gi|122937227 U2-associated SR140 protein [Homo sapiens] 50 7e-06
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 50 1e-05
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens] 49 1e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 49 2e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 49 2e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 49 2e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 48 4e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 48 4e-05
gi|10864047 epidermal growth factor receptor pathway substrate 1... 48 4e-05
gi|38569484 kinesin family member 21A [Homo sapiens] 47 5e-05
gi|148746195 trichohyalin [Homo sapiens] 47 6e-05
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 47 8e-05
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 47 8e-05
>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
[Homo sapiens]
Length = 731
Score = 1457 bits (3771), Expect = 0.0
Identities = 731/731 (100%), Positives = 731/731 (100%)
Query: 1 MVKPKYKGRSTINPSKASTNPDRVQGAGGQNMRDRATIRRLNMYRQKERRNSRGKIIKPL 60
MVKPKYKGRSTINPSKASTNPDRVQGAGGQNMRDRATIRRLNMYRQKERRNSRGKIIKPL
Sbjct: 1 MVKPKYKGRSTINPSKASTNPDRVQGAGGQNMRDRATIRRLNMYRQKERRNSRGKIIKPL 60
Query: 61 QYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVMKDPYKVVMKQSKLPMSL 120
QYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVMKDPYKVVMKQSKLPMSL
Sbjct: 61 QYQSTVASGTVARVEPNIKWFGNTRVIKQSSLQKFQEEMDTVMKDPYKVVMKQSKLPMSL 120
Query: 121 LHDRIRPHNLKVHILDTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQGKDR 180
LHDRIRPHNLKVHILDTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQGKDR
Sbjct: 121 LHDRIRPHNLKVHILDTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQGKDR 180
Query: 181 DLVTEDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETY 240
DLVTEDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETY
Sbjct: 181 DLVTEDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETY 240
Query: 241 LKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ 300
LKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ
Sbjct: 241 LKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ 300
Query: 301 FGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLI 360
FGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLI
Sbjct: 301 FGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLI 360
Query: 361 DCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAED 420
DCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAED
Sbjct: 361 DCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAED 420
Query: 421 FLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLE 480
FLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLE
Sbjct: 421 FLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLE 480
Query: 481 VVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVP 540
VVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVP
Sbjct: 481 VVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVP 540
Query: 541 QFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKAL 600
QFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKAL
Sbjct: 541 QFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKAL 600
Query: 601 DEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRK 660
DEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRK
Sbjct: 601 DEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRK 660
Query: 661 AQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQ 720
AQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQ
Sbjct: 661 AQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQ 720
Query: 721 KHKRKKFRQKQ 731
KHKRKKFRQKQ
Sbjct: 721 KHKRKKFRQKQ 731
>gi|9506611 guanine nucleotide binding protein-like 3
(nucleolar)-like [Homo sapiens]
Length = 582
Score = 179 bits (453), Expect = 1e-44
Identities = 111/334 (33%), Positives = 171/334 (51%), Gaps = 32/334 (9%)
Query: 204 KRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTW 263
K + E KV++ SDV+++VLDARDP+G R +E + + + K L+ VLNK DLVP
Sbjct: 122 KAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKE 181
Query: 264 ATKRWVAVLSQDYPTLAFHASLTNP------------------------FGKGAFIQLLR 299
++W+ L + PT+AF AS + FG +++L
Sbjct: 182 VVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLG 241
Query: 300 QFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFL 359
+ +L + I VG +G PNVGKSS+IN+L+ + C+V + G TK Q + L + I L
Sbjct: 242 NYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRL 301
Query: 360 IDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAE 419
+D PG+V P +SE +L+ V V+K+ P + +L+R E IS Y + ++ E
Sbjct: 302 LDAPGIV-PGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTE 360
Query: 420 DFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSS-S 478
FL +A R GK KGG + K VL DW G+I F++ PP A LP+ S
Sbjct: 361 HFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPP------ATHTLPTHLS 414
Query: 479 LEVVPEAAQNNPGEEVTETAGEGSESIIKEETEE 512
E+V E + E+ + + E + E++E
Sbjct: 415 AEIVKEMTEVFDIEDTEQANEDTMECLATGESDE 448
>gi|45643129 guanine nucleotide binding protein-like 3 isoform 2
[Homo sapiens]
Length = 537
Score = 171 bits (434), Expect = 2e-42
Identities = 122/421 (28%), Positives = 204/421 (48%), Gaps = 54/421 (12%)
Query: 190 RNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKH 249
+ E + + K+ K EL KVI++SDVV++VLDARDP+G R P +E + + K
Sbjct: 102 KTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQ-KK 160
Query: 250 LIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ--------- 300
L+ +LNK DLVP + W+ L ++ PT+ F AS T P KG + ++
Sbjct: 161 LVLILNKSDLVPKENLESWLNYLKKELPTVVFRAS-TKPKDKGKITKRVKAKKNAAPFRS 219
Query: 301 ---FGK----------LHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKV 347
FGK T K I VG IG+PNVGKSS+IN+L+ +++CNV G T+
Sbjct: 220 EVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRS 279
Query: 348 WQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYIS 407
Q + L ++I +ID P + +S + + L+ +E +K P + A+L +A +
Sbjct: 280 MQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVK-PMEAASAILSQADARQVV 338
Query: 408 KTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEP 467
Y + + N+ +F LA R G KGG P+++ K++ ++W + ++ PP +
Sbjct: 339 LKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTS-- 396
Query: 468 LVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILT 527
P + S+ V ++ N EE E+N+ Q +
Sbjct: 397 -WTPPPYFNESIVVDMKSGFN------------------LEELEKNN--------AQSIR 429
Query: 528 RVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEE 587
++ +++ Q SG +E D+ EEL + ++EE+E +D +E+ E +E
Sbjct: 430 AIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 489
Query: 588 N 588
N
Sbjct: 490 N 490
>gi|45643127 guanine nucleotide binding protein-like 3 isoform 2
[Homo sapiens]
Length = 537
Score = 171 bits (434), Expect = 2e-42
Identities = 122/421 (28%), Positives = 204/421 (48%), Gaps = 54/421 (12%)
Query: 190 RNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKH 249
+ E + + K+ K EL KVI++SDVV++VLDARDP+G R P +E + + K
Sbjct: 102 KTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQ-KK 160
Query: 250 LIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ--------- 300
L+ +LNK DLVP + W+ L ++ PT+ F AS T P KG + ++
Sbjct: 161 LVLILNKSDLVPKENLESWLNYLKKELPTVVFRAS-TKPKDKGKITKRVKAKKNAAPFRS 219
Query: 301 ---FGK----------LHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKV 347
FGK T K I VG IG+PNVGKSS+IN+L+ +++CNV G T+
Sbjct: 220 EVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRS 279
Query: 348 WQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYIS 407
Q + L ++I +ID P + +S + + L+ +E +K P + A+L +A +
Sbjct: 280 MQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVK-PMEAASAILSQADARQVV 338
Query: 408 KTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEP 467
Y + + N+ +F LA R G KGG P+++ K++ ++W + ++ PP +
Sbjct: 339 LKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTS-- 396
Query: 468 LVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILT 527
P + S+ V ++ N EE E+N+ Q +
Sbjct: 397 -WTPPPYFNESIVVDMKSGFN------------------LEELEKNN--------AQSIR 429
Query: 528 RVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEE 587
++ +++ Q SG +E D+ EEL + ++EE+E +D +E+ E +E
Sbjct: 430 AIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 489
Query: 588 N 588
N
Sbjct: 490 N 490
>gi|45593130 guanine nucleotide binding protein-like 3 isoform 1
[Homo sapiens]
Length = 549
Score = 171 bits (434), Expect = 2e-42
Identities = 122/421 (28%), Positives = 204/421 (48%), Gaps = 54/421 (12%)
Query: 190 RNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKH 249
+ E + + K+ K EL KVI++SDVV++VLDARDP+G R P +E + + K
Sbjct: 114 KTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQ-KK 172
Query: 250 LIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ--------- 300
L+ +LNK DLVP + W+ L ++ PT+ F AS T P KG + ++
Sbjct: 173 LVLILNKSDLVPKENLESWLNYLKKELPTVVFRAS-TKPKDKGKITKRVKAKKNAAPFRS 231
Query: 301 ---FGK----------LHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKV 347
FGK T K I VG IG+PNVGKSS+IN+L+ +++CNV G T+
Sbjct: 232 EVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRS 291
Query: 348 WQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYIS 407
Q + L ++I +ID P + +S + + L+ +E +K P + A+L +A +
Sbjct: 292 MQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVK-PMEAASAILSQADARQVV 350
Query: 408 KTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEP 467
Y + + N+ +F LA R G KGG P+++ K++ ++W + ++ PP +
Sbjct: 351 LKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTS-- 408
Query: 468 LVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILT 527
P + S+ V ++ N EE E+N+ Q +
Sbjct: 409 -WTPPPYFNESIVVDMKSGFN------------------LEELEKNN--------AQSIR 441
Query: 528 RVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEE 587
++ +++ Q SG +E D+ EEL + ++EE+E +D +E+ E +E
Sbjct: 442 AIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 501
Query: 588 N 588
N
Sbjct: 502 N 502
>gi|223029424 large subunit GTPase 1 [Homo sapiens]
Length = 658
Score = 92.0 bits (227), Expect = 2e-18
Identities = 53/189 (28%), Positives = 95/189 (50%), Gaps = 16/189 (8%)
Query: 296 QLLRQFGKLHTDKK----QISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYI 351
+LL F +LHT +K Q++VG +GYPNVGKSS INT+ K +V+ G TK +Q +
Sbjct: 368 ELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTL 427
Query: 352 TLMRRIFLIDCPGVVYPS-EDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTY 410
+ + L DCPG+V PS ++ ++ G++ +++++ + V + + TY
Sbjct: 428 YVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATY 487
Query: 411 KID-----------SWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFF 459
I+ +E+ L + G + G+PD + +L D+ G++ +
Sbjct: 488 GINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYC 547
Query: 460 VKPPNAEPL 468
PP +P+
Sbjct: 548 HPPPGRDPV 556
Score = 55.1 bits (131), Expect = 2e-07
Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 11/137 (8%)
Query: 151 KRPNLFASDMQSLIENAEMSTESYDQGKDRDLVTEDTGVRNEAQEEIYKKGQSKRI--WG 208
+RPN + ++ AE KD L VR E ++++ + + W
Sbjct: 115 RRPNWNQNTTPEELKQAE---------KDNFLEWRRQLVRLEEEQKLILTPFERNLDFWR 165
Query: 209 ELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRW 268
+L++VI+ SD+VVQ++DAR+P+ R +E Y+K+ K + ++NK DL+ W
Sbjct: 166 QLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAW 225
Query: 269 VAVLSQDYPTLAFHASL 285
++ + F ++L
Sbjct: 226 AMYFEKEDVKVIFWSAL 242
>gi|38788319 guanine nucleotide binding protein-like 1 [Homo
sapiens]
Length = 607
Score = 80.5 bits (197), Expect = 5e-15
Identities = 63/223 (28%), Positives = 103/223 (46%), Gaps = 16/223 (7%)
Query: 311 ISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSE 370
+++G +G+PNVGKSS+IN L +KV +V+ G T+ +Q L + L DCPG+++PS
Sbjct: 361 VTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSL 420
Query: 371 DSETDIVLKGVVQVEKIKSPEDHIGAV-----------LERAKPEYISKTYKIDSWENAE 419
VL G+ + +I+ P +G + L + E S + +W+ E
Sbjct: 421 LPRQLQVLAGIYPIAQIQEPYTAVGYLASRIPVQALLHLRHPEAEDPSAEHPWCAWDICE 480
Query: 420 DFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPN-AEPLVAPQLLPSSS 478
+ EK ++T K + D+ +L GR+ PP +E + P ++
Sbjct: 481 AWAEKRGYKTAKAARN---DVYRAANSLLRLAVDGRLSLCFHPPGYSEQKGTWESHPETT 537
Query: 479 LEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTE 521
VV + G+E E E S S +EE EE+ D E
Sbjct: 538 ELVVLQGRVGPAGDEEEEEEEELSSS-CEEEGEEDRDADEEGE 579
Score = 46.6 bits (109), Expect = 8e-05
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 207 WGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATK 266
W +L++V++ SD+V+ + D R P+ P + Y+ E L+ VLNK DL P
Sbjct: 178 WRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTGELGLA-LVLVLNKVDLAPPALVV 236
Query: 267 RWVAVLSQDYPTL 279
W Q YP L
Sbjct: 237 AWKHYFHQHYPQL 249
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 56.2 bits (134), Expect = 1e-07
Identities = 42/174 (24%), Positives = 82/174 (47%), Gaps = 17/174 (9%)
Query: 558 ELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAK 617
E E E E+E++++R E+ + E + K + K + +K K K +
Sbjct: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK-ERREKERRKRKKE 100
Query: 618 KFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRAL 677
K R +G E+ K +++RK E + R K+ K+RK +R +E++ + R
Sbjct: 101 KKKRERKQRGRRER---KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE--RGK 155
Query: 678 TSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
++R++ +++R KK + RNR ++K ++ +RKK R+K+
Sbjct: 156 RERKRKKRKKEEREKK-----------RERNRKERKKERERKERRERKKERKKE 198
Score = 50.1 bits (118), Expect = 7e-06
Identities = 42/167 (25%), Positives = 78/167 (46%), Gaps = 15/167 (8%)
Query: 565 EEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRI 624
+ E E++++R + E+ E E+E K ++K K ++ + + K+ +
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKK-----EKKKRKKRERGKERERKRKEREKQ 85
Query: 625 SKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRR 684
K EK K ++++K E R KK K+RK E+E NK R K+RR+
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERK-----ERERENKQRRERKRKKRRK 140
Query: 685 AVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
R++ K+ R + R R K+K + E ++ + +K R+K+
Sbjct: 141 KKRRKERKREKER-----GKRERKRKKRKKEEREKKRERNRKERKKE 182
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/138 (20%), Positives = 65/138 (47%), Gaps = 3/138 (2%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
E + + + +E +E++R ++ + E + G + K E+ + ++ ++ +
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPR 675
K+ R + EK K E +RK +++ ++ + K+RK +RE ++ K R
Sbjct: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER 195
Query: 676 ALTSKERRRAVRQQRPKK 693
KERR+ +++ +K
Sbjct: 196 ---KKERRKKKERKKDRK 210
Score = 35.8 bits (81), Expect = 0.15
Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 17/138 (12%)
Query: 596 VIKALDEKIA-KYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSK 654
++KA+ + A K L S + K + E+RK E R K
Sbjct: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGK 60
Query: 655 KGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKT 714
K KK++ +RE +E K KER + +++R K+ K + KK+
Sbjct: 61 KEKKKRKKRERGKERERKR------KEREKQRKERREKE---------RRKRKKEKKKRE 105
Query: 715 NDSEGQKH-KRKKFRQKQ 731
G++ K+KK R+++
Sbjct: 106 RKQRGRRERKKKKERKER 123
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 54.3 bits (129), Expect = 4e-07
Identities = 53/194 (27%), Positives = 93/194 (47%), Gaps = 28/194 (14%)
Query: 551 EVSDLEEELESFSD---EEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKY 607
E+ + E E+E+ + E E E++++R + E+ E E+E K K K
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK--------KEKKG 88
Query: 608 QKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKR--KAQREE 665
++ ++ + KK + +K EK E+RK E+ R SK+GK+R K +R+
Sbjct: 89 ERKKEERERKKRRREKENKEGEEK------EKRKKKEKKERGRT-SKEGKERERKEERKR 141
Query: 666 EQEHSNKAPRALTSKERRRAVRQQRPKK-VGVRYYETHNVKNRNRNKKKTNDSEGQKHK- 723
E+ + + KER R R++R +K VG + E + + R K++ N E +K +
Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
Query: 724 ------RKKFRQKQ 731
RKK R+K+
Sbjct: 202 RKERRERKKERKKK 215
Score = 51.6 bits (122), Expect = 3e-06
Identities = 39/176 (22%), Positives = 79/176 (44%), Gaps = 15/176 (8%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
E+E + ++E++ E+++++ E E+EN + K K ++K ++ +
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK--------ERGR 125
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPR 675
K R K K + E +RK E + + +K ++RK E+E+E K +
Sbjct: 126 TSKEGKERERKE-ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184
Query: 676 ALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+ER R R++ R + + + R KK+ E QK ++ +R+K+
Sbjct: 185 ERKKRERNRKERKKE------RERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 53.5 bits (127), Expect = 7e-07
Identities = 47/204 (23%), Positives = 92/204 (45%), Gaps = 29/204 (14%)
Query: 552 VSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGND------TKAVIKALDEKIA 605
+SD+EE +E + +EE+EEQE+ ++ E+ +E EE D +A ++E
Sbjct: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
Query: 606 KYQKFL-----------DKAKAKKFSAVRISKGLSE---KIFAKPEEQRKTLEE-----D 646
K + F+ ++ R+ K L+E I A E ++K EE D
Sbjct: 61 KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKD 120
Query: 647 VDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKE----RRRAVRQQRPKKVGVRYYETH 702
+R +++ ++++ + E E+E N+ +E RR+A + R KK
Sbjct: 121 RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 180
Query: 703 NVKNRNRNKKKTNDSEGQKHKRKK 726
+ + ++K+ + ++ K+KK
Sbjct: 181 GYIQKAQTERKSGKRQTEREKKKK 204
Score = 35.4 bits (80), Expect = 0.19
Identities = 55/276 (19%), Positives = 110/276 (39%), Gaps = 35/276 (12%)
Query: 477 SSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKI 536
S +E V E + EE E A E +E+ + ETEE + + + E ++ +
Sbjct: 2 SDIEEVVEEYEEEEQEEQEEAAEEDAEA--EAETEE-TRAEEDEEEEEAKEAEDGPMEES 58
Query: 537 NVVPQFSGDDLVPVEVSD-------------LEEELES--------FSDEEEEEQE---- 571
P+ +LVP ++ D +E++L F + ++EE+E
Sbjct: 59 KPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSL 118
Query: 572 ------QQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKK-FSAVRI 624
++ + AE+ E E + A +A E+ +K D+A+ KK S +
Sbjct: 119 KDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMH 178
Query: 625 SKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRR 684
G +K + + ++ E + + +++ K E + KA S
Sbjct: 179 FGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLE 238
Query: 685 AVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQ 720
A + +K + YE + ++NR + +K + + G+
Sbjct: 239 AEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 274
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 53.1 bits (126), Expect = 9e-07
Identities = 55/252 (21%), Positives = 105/252 (41%), Gaps = 6/252 (2%)
Query: 480 EVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQ-QILTRVRQNFGKINV 538
E V ++ Q N + E E E +EE EE + E Q +++ + +
Sbjct: 166 ETVTKSYQKNDWRDAEENKKEDKEK--EEEEEEKPKRGSIGENQVEVMVEEKTTESQEET 223
Query: 539 VPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIK 598
V + + E EEE E SDE ++ + +D E + E E + + + IK
Sbjct: 224 VVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERA--EAERARLEAEERERIK 281
Query: 599 ALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKK 658
A +K ++ +A+ K + R + E+ + EE+R E + ++
Sbjct: 282 AEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEE 341
Query: 659 RKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSE 718
R+ +EEE+ + + R + +E+R A +QR + + K + ++K + +
Sbjct: 342 RQRIKEEEKRAAEERQR-IKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQ 400
Query: 719 GQKHKRKKFRQK 730
K K +K QK
Sbjct: 401 ETKIKGEKVEQK 412
Score = 38.9 bits (89), Expect = 0.017
Identities = 73/340 (21%), Positives = 144/340 (42%), Gaps = 40/340 (11%)
Query: 399 ERAKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPF 458
E + E ++K+Y+ + W +AE+ K + + + +P ++G+ ++
Sbjct: 161 EIEETETVTKSYQKNDWRDAEE--NKKEDKEKEEEEEEKPKRGSIGE--------NQVEV 210
Query: 459 FVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIK-EETEENSHCD 517
V+ E ++ + ++ E P +E E +GS+ I E+ EE
Sbjct: 211 MVEEKTTESQEETVVMSLKNGQISSE----EPKQE--EEREQGSDEISHHEKMEEEDKER 264
Query: 518 ANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEE----EEQEQQ 573
A E ++ R+ + D + E + +E E ++ + E E EE+E+
Sbjct: 265 AEAERARLEAEERERI-------KAEQDKKIADERARIEAEEKAAAQERERREAEERERM 317
Query: 574 RDD----AEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLS 629
R++ AEE EEE + + IK +EK A ++ K + K+ + R
Sbjct: 318 REEEKRAAEERQRIKEEEKRAAEERQRIKE-EEKRAAEERQRIKEEEKRAAEERQRARAE 376
Query: 630 EKIFAKPEEQR--KTLEEDVDDRAPSK-KGKKRKAQREEEQEHSNKAPRALTSKERRRAV 686
E+ AK EEQ+ K LEE +K KG+K + + E + + KA + + AV
Sbjct: 377 EEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKA----QEDKLQTAV 432
Query: 687 RQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKK 726
+++ ++ G + ++ K + + +K K+ K
Sbjct: 433 LKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 472
Score = 34.7 bits (78), Expect = 0.32
Identities = 35/175 (20%), Positives = 73/175 (41%), Gaps = 26/175 (14%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
+E L +EE Q + + +S P+EE T ++ DE FL++
Sbjct: 47 QERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE-----AAFLERLA 101
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPR 675
++ R K L E + E++K + + D + S ++ + ++ A
Sbjct: 102 RRE---ERRQKRLQEAL-----ERQKEFDPTITDASLSLPSRRMQ---------NDTAEN 144
Query: 676 ALTSKERRRAVRQQR----PKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKK 726
T KE + RQ+R + + Y+ ++ ++ NKK+ + E ++ ++ K
Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPK 199
Score = 31.6 bits (70), Expect = 2.7
Identities = 35/197 (17%), Positives = 73/197 (37%), Gaps = 38/197 (19%)
Query: 570 QEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQK-------------------F 610
+ Q D AE ++E EE++ + I+ + YQK
Sbjct: 135 RRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE 194
Query: 611 LDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQR------- 663
+K K ++ + EK E Q +T+ + + S + K++ +R
Sbjct: 195 EEKPKRGSIGENQVEVMVEEK---TTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEI 251
Query: 664 ------EEEQEHSNKAPRALTSKERRRAVRQQRPKKVG---VRYYETHNVKNRNRNKKKT 714
EEE + +A RA E R ++ ++ KK+ R + R +++
Sbjct: 252 SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREA 311
Query: 715 NDSEGQKHKRKKFRQKQ 731
+ E + + K+ +++
Sbjct: 312 EERERMREEEKRAAEER 328
Score = 30.4 bits (67), Expect = 6.1
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 8/65 (12%)
Query: 630 EKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQ 689
E++ K EE+RK LEE+ R + +K REEE++ R ERRRA +
Sbjct: 566 EELKKKREERRKVLEEEEQRRKQEEADRK---LREEEEKR-----RLKEEIERRRAEAAE 617
Query: 690 RPKKV 694
+ +K+
Sbjct: 618 KRQKM 622
>gi|93277113 GTP_binding protein [Homo sapiens]
Length = 334
Score = 52.8 bits (125), Expect = 1e-06
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 23/236 (9%)
Query: 218 DVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLS-QDY 276
D +++V DAR P+ R+P + L KP HL+ VLNK DL ++ + L +
Sbjct: 50 DCIIEVHDARIPLSGRNPLFQETLGL-KP--HLL-VLNKMDLADLTEQQKIMQHLEGEGL 105
Query: 277 PTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGF----IGYPNVGKSSVINTLRS 332
+ F + + K + G+ H ++ ++ + IG PNVGKSS+IN+LR
Sbjct: 106 KNVIFTNCVKDENVKQIIPMVTELIGRSHRYHRKENLEYCIMVIGVPNVGKSSLINSLRR 165
Query: 333 K-----KVCNVAPIAGETK-VWQYITLMRR--IFLIDCPGVVYP---SEDSETDIVLKGV 381
+ K V G T+ V I + R +FL+D PGV+ P S ++ + L G
Sbjct: 166 QHLRKGKATRVGGEPGITRAVMSKIQVSERPLMFLLDTPGVLAPRIESVETGLKLALCGT 225
Query: 382 VQVEKI--KSPEDHIGAVLERAKPEYISKTYKIDS-WENAEDFLEKLAFRTGKLLK 434
V + ++ D++ L + + + Y + S +N E L+ +A + GK K
Sbjct: 226 VLDHLVGEETMADYLLYTLNKHQRFGYVQHYGLGSACDNVERVLKSVAVKLGKTQK 281
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 52.4 bits (124), Expect = 1e-06
Identities = 36/181 (19%), Positives = 82/181 (45%), Gaps = 5/181 (2%)
Query: 554 DLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDK 613
D EE +E + E+E++ Q + E E E + + +++ +EK+ + ++ + +
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 614 AKAKKFSAVRISKGLSEKIFAKPE---EQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHS 670
+ K + + EK++ + E EQ + + E R P +K K + ++ +EQE
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWE--QQRLPEQKEKLWEHEKMQEQEKM 679
Query: 671 NKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQK 730
+ + +E+ Q++ KK + R R KK + E + + +K +++
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ 739
Query: 731 Q 731
+
Sbjct: 740 E 740
Score = 41.2 bits (95), Expect = 0.003
Identities = 36/190 (18%), Positives = 91/190 (47%), Gaps = 18/190 (9%)
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKF 610
E ++E+ + D+EE+ QE++R E EEE ++ +EK+ K ++
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE--------TMREQEEKMQKQEEN 479
Query: 611 LDKAKAKKFSAVRISKGLSEKIF--AKPEEQRKTL---EEDVDDR----APSKKGKKRKA 661
+ + + K++ R+ + EK++ K +EQ + + EE + D+ KK +++
Sbjct: 480 MWEQEEKEWQQQRLPE-QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 538
Query: 662 QREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQK 721
RE+E + + + +++ ++ KK + +T + + + R +++ + E +
Sbjct: 539 MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598
Query: 722 HKRKKFRQKQ 731
+ ++ ++Q
Sbjct: 599 REEEEMMREQ 608
Score = 38.9 bits (89), Expect = 0.017
Identities = 33/143 (23%), Positives = 63/143 (44%), Gaps = 8/143 (5%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
E+E E +E EQE+Q + EE E EE+ + K + +E++ + +K + + +
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK--MWRQEERLWEQEKQMREQE 389
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQR------KTLEEDVDDRAPSKKGKKRKAQREEEQEH 669
K E++ K E R + +E+ +++ ++ KK + Q E+ QE
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449
Query: 670 SNKAPRALTSKERRRAVRQQRPK 692
R +E +R+Q K
Sbjct: 450 ERIREREKKMREEEETMREQEEK 472
Score = 38.5 bits (88), Expect = 0.022
Identities = 44/234 (18%), Positives = 105/234 (44%), Gaps = 18/234 (7%)
Query: 507 KEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEE 566
K + +E D +M++ R+R+ K+ ++++ + ++E+ E ++E
Sbjct: 570 KTQEQEKKTWDQEEKMREE-ERMREREKKMR-----EEEEMMREQEEKMQEQEEKMQEQE 623
Query: 567 EE--EQEQQRDDAEESSSEPEEENVGNDTK----AVIKALDEKIAKYQKFLDKAKAKKFS 620
E+ EQE++ + EE E EE+ + K + EK+ +++K ++ K ++
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE-Q 682
Query: 621 AVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSK 680
+I + EK+ K +EQ K + R ++ K REEE+ + + +
Sbjct: 683 EEKIWE--QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 681 ERRRAVRQQRPKKVGVRYYETHNVKNRNR---NKKKTNDSEGQKHKRKKFRQKQ 731
E+ + ++ ++ + + + + R K+K + E + + K + Q++
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Score = 36.2 bits (82), Expect = 0.11
Identities = 26/120 (21%), Positives = 60/120 (50%), Gaps = 5/120 (4%)
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKF 610
E L E+ E + E+ +++++ + EE + EE+ G + K ++ +EK+ ++
Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEK--MRGQEEKMRGQEEK 823
Query: 611 LDKAKAKKFSAVRISKGLSEKIFA---KPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQ 667
+ + K + G EK++ K EE+ + EE + ++ +G++ K + +EE+
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Score = 35.8 bits (81), Expect = 0.15
Identities = 64/349 (18%), Positives = 143/349 (40%), Gaps = 57/349 (16%)
Query: 393 HIGAVLERAKPEYISKTYKIDSW----ENAEDFLEKLAFR---TGKLLKGGEPDLQTVGK 445
H L+RA ++ K D + D L +R T + LK +LQ K
Sbjct: 176 HFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQE--K 233
Query: 446 MVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESI 505
+ L + ++ I VK + A LLP + E EE+ E E
Sbjct: 234 LPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE-EELRE-----QEKK 287
Query: 506 IKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDE 565
I+++ E+ M + R+R+ GK+ ++ + + L E+ + ++
Sbjct: 288 IRKQEEK---------MWRQEERLREQEGKMR-----EQEEKMWRQEKRLREQEKELREQ 333
Query: 566 EEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRIS 625
E+E +EQ+ +E + +EE + +EK+ + ++ + + + + +
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQ--------EEKMREQEEKMWRQEERLWE----- 380
Query: 626 KGLSEKIFAKPEEQRKTLEE---DVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKER 682
EK + E++ + EE + D+R K+ + R+ ++ EQ + + + +E+
Sbjct: 381 ---QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK 437
Query: 683 RRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+ ++++ ++ + R R KK + E + + +K ++++
Sbjct: 438 KTRDQEEKMQE---------EERIREREKKMREEEETMREQEEKMQKQE 477
Score = 35.0 bits (79), Expect = 0.25
Identities = 29/112 (25%), Positives = 59/112 (52%), Gaps = 13/112 (11%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
EEE+ +E+ +EQE++ + EE E EE+ + +EK+ + Q+ L + K
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK---------MWEQEEKMWEQQR-LPEQK 774
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQ 667
K + ++ + EKI+ + EE+ + EE + + +G++ K + +EE+
Sbjct: 775 EKLWEHEKMQE--QEKIW-EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823
Score = 33.5 bits (75), Expect = 0.72
Identities = 31/188 (16%), Positives = 85/188 (45%), Gaps = 11/188 (5%)
Query: 555 LEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFL--- 611
++E+ E ++EE+ +EQ+ + E+E + + ++ +E++ + + L
Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409
Query: 612 -DKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREE---EQ 667
++ + ++ ++ K EK + E++ + EE + + ++ +K+ + EE EQ
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQ 469
Query: 668 EHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRN----RNKKKTNDSEGQKHK 723
E + ++ + +QQR + + +E ++ + ++K D E +
Sbjct: 470 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 529
Query: 724 RKKFRQKQ 731
KK +++
Sbjct: 530 EKKMWRQE 537
Score = 31.6 bits (70), Expect = 2.7
Identities = 39/183 (21%), Positives = 81/183 (44%), Gaps = 17/183 (9%)
Query: 557 EELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKA 616
E+ E ++EE+ EQQR E+ E E + K ++ +EKI + +K K +
Sbjct: 642 EQEEKMWEQEEKMWEQQRLP-EQKEKLWEHEKMQEQEK--MQEQEEKIWEQEKMEKKTQE 698
Query: 617 KKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQ--EHSNKAP 674
++ K E+ + E++ + EE + ++ + ++ K Q +EE+ E K
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK-- 756
Query: 675 RALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNR---NKKKTNDSE----GQKHKRKKF 727
++ + QQR + + +E ++ + + ++K D E GQ+ K +
Sbjct: 757 ---MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQ 813
Query: 728 RQK 730
+K
Sbjct: 814 EEK 816
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/181 (24%), Positives = 79/181 (43%), Gaps = 12/181 (6%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
EEE + +EEEEE+E+ ++ EE E EEEN+ + + K I + + F+ K K
Sbjct: 1073 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK 1132
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPR 675
+ RI+ ++ + + E + L E D+ + + + E E E + P
Sbjct: 1133 RGR-KRRRINSSVTTETIS---ETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPV 1188
Query: 676 ALTSKERRRAVRQQRPKKVGVRYYETHNVKN-----RNRNKKKTNDSEGQKHKRKKFRQK 730
+ + + ++Q ++ G + H KN N N +N EG K + + K
Sbjct: 1189 LRKAFQHQPGKKRQTEEEEG---KDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCK 1245
Query: 731 Q 731
Q
Sbjct: 1246 Q 1246
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/155 (20%), Positives = 73/155 (47%), Gaps = 9/155 (5%)
Query: 563 SDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAV 622
S+EE E +++ E++S +EE T+A + K+ K+L +++ +
Sbjct: 998 SEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGE 1057
Query: 623 RISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKER 682
R K ++ EE+ + EE+ ++ + ++ + + EEE+E + ++ +K +
Sbjct: 1058 RGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117
Query: 683 RRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDS 717
A++++RP + K R R +++ N S
Sbjct: 1118 SVAIKRKRPFVL---------KKKRGRKRRRINSS 1143
Score = 42.0 bits (97), Expect = 0.002
Identities = 57/233 (24%), Positives = 89/233 (38%), Gaps = 44/233 (18%)
Query: 464 NAEPLVAPQLLPSSSLEVVPEAAQNNPGEE--------VTETAGEGSESIIKEETEENSH 515
N EPL Q+ P + + + QN + ET E E + EE +E S
Sbjct: 1238 NPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSE 1297
Query: 516 CDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEE---------------ELE 560
+ +I V++ +G+ L+P E + EE E +
Sbjct: 1298 GKTSPSPIRIEEEVKE-----------TGEALLPQEENRREETCAPVSPNTSPGEKPEDD 1346
Query: 561 SFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQ-KFLDKAKAKKF 619
EEEEE+E++ ++ EE EEE GN K D AK Q K + +K
Sbjct: 1347 LIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK------DPDGAKSQEKEEPEISTEKE 1400
Query: 620 SAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNK 672
+ R+ E+ + EE + D DD S + + ++EE S K
Sbjct: 1401 DSARLDDHEEEE--EEDEEPSHNEDHDADDEDDSHM-ESAEVEKEELPRESFK 1450
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 50.8 bits (120), Expect = 4e-06
Identities = 44/147 (29%), Positives = 81/147 (55%), Gaps = 11/147 (7%)
Query: 554 DLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDK 613
D E +S S+EEEEE+E++ ++ EE E E+EN +D+K+ K +KI K K DK
Sbjct: 1395 DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN--DDSKSPGKG-RKKIRKILKD-DK 1450
Query: 614 AKAKKFSAVRISKGLSEKIFAKPEEQRKTLEE--DVDDRAPSKKGKKRKAQREEEQEHSN 671
+ + +A++ + ++I A+ E +R+ L E +++D +P+K K +E++E
Sbjct: 1451 LRTETQNALKEEEERRKRI-AEREREREKLREVIEIEDASPTKCPITTKLVLDEDEE--T 1507
Query: 672 KAPRALTSKERRRAVRQQRPKKVGVRY 698
K P L R ++ + + GV++
Sbjct: 1508 KEP--LVQVHRNMVIKLKPHQVDGVQF 1532
Score = 43.5 bits (101), Expect = 7e-04
Identities = 50/259 (19%), Positives = 119/259 (45%), Gaps = 39/259 (15%)
Query: 508 EETEENSHCDANTEMQQILTRVRQNF--GKINVVPQFSGDDL----VPVEVSD------- 554
E+ ++NS + +++ Q+I V +N Q SGD+ VPV V D
Sbjct: 1171 EDDDQNSIGEGSSDEQKIKP-VTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP 1229
Query: 555 ---------LEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGND-TKAVIKA---LD 601
LEE + S +E+ + + ++ ++ + + EEN G++ K + + D
Sbjct: 1230 ENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSD 1289
Query: 602 EKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEE--------QRKTLEEDVDDRAPS 653
+ +K ++ + K + G +K KP+E +RK ED +D
Sbjct: 1290 SEESKKPRYRHRLLRHKLTVSDGESGEEKK--TKPKEHKEVKGRNRRKVSSEDSEDSDFQ 1347
Query: 654 KKG-KKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKK 712
+ G + ++ E+EQ ++ + +E +R+ +Q++ K+ ++ E + +N++ +++
Sbjct: 1348 ESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKK-KRRRIKVQEDSSSENKSNSEE 1406
Query: 713 KTNDSEGQKHKRKKFRQKQ 731
+ + E ++ + ++ +++
Sbjct: 1407 EEEEKEEEEEEEEEEEEEE 1425
Score = 40.8 bits (94), Expect = 0.005
Identities = 49/223 (21%), Positives = 91/223 (40%), Gaps = 17/223 (7%)
Query: 483 PEAAQNNPGEEVTETAG-EGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQ 541
PE + G++ E G E +++ + E++ +S + L R K+ V
Sbjct: 1258 PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR-----HKLTVSDG 1312
Query: 542 FSGDD--LVPVEVSDLE-EELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIK 598
SG++ P E +++ S E+ E+ + Q E SE E+E A
Sbjct: 1313 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1372
Query: 599 ALDEKIAKYQ--KFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDV------DDR 650
L+E Y+ K + K ++ S+ E+ K EE+ + EE+ DD
Sbjct: 1373 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1432
Query: 651 APSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKK 693
KG+K+ + ++ + + AL +E RR +R ++
Sbjct: 1433 KSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERE 1475
Score = 31.6 bits (70), Expect = 2.7
Identities = 45/238 (18%), Positives = 99/238 (41%), Gaps = 22/238 (9%)
Query: 506 IKEETEENSHCDANT--EMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFS 563
+ E E++ H T ++Q L+ + + F K + + S DD + E++ S
Sbjct: 901 VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF 960
Query: 564 DEEEEEQEQQRDDAEESSSE-PEEENVGNDTKAVIKALD---EKIAKYQKFLDKAKAKK- 618
++ + EQQ + + + + + PE E + + K + + + + K +K DK KK
Sbjct: 961 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1020
Query: 619 ----FSAVRISKGLS----------EKIFAKPEEQRKTLEEDVDDRAP-SKKGKKRKAQR 663
++ KG S + + +++ K L + R S ++ + +
Sbjct: 1021 ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK 1080
Query: 664 EEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQK 721
E+ S+K + + +ERR ++ K++ + ++ NKKK + +K
Sbjct: 1081 EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKK 1138
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 50.8 bits (120), Expect = 4e-06
Identities = 44/147 (29%), Positives = 81/147 (55%), Gaps = 11/147 (7%)
Query: 554 DLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDK 613
D E +S S+EEEEE+E++ ++ EE E E+EN +D+K+ K +KI K K DK
Sbjct: 1433 DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN--DDSKSPGKG-RKKIRKILKD-DK 1488
Query: 614 AKAKKFSAVRISKGLSEKIFAKPEEQRKTLEE--DVDDRAPSKKGKKRKAQREEEQEHSN 671
+ + +A++ + ++I A+ E +R+ L E +++D +P+K K +E++E
Sbjct: 1489 LRTETQNALKEEEERRKRI-AEREREREKLREVIEIEDASPTKCPITTKLVLDEDEE--T 1545
Query: 672 KAPRALTSKERRRAVRQQRPKKVGVRY 698
K P L R ++ + + GV++
Sbjct: 1546 KEP--LVQVHRNMVIKLKPHQVDGVQF 1570
Score = 43.5 bits (101), Expect = 7e-04
Identities = 50/259 (19%), Positives = 119/259 (45%), Gaps = 39/259 (15%)
Query: 508 EETEENSHCDANTEMQQILTRVRQNF--GKINVVPQFSGDDL----VPVEVSD------- 554
E+ ++NS + +++ Q+I V +N Q SGD+ VPV V D
Sbjct: 1209 EDDDQNSIGEGSSDEQKIKP-VTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP 1267
Query: 555 ---------LEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGND-TKAVIKA---LD 601
LEE + S +E+ + + ++ ++ + + EEN G++ K + + D
Sbjct: 1268 ENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSD 1327
Query: 602 EKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEE--------QRKTLEEDVDDRAPS 653
+ +K ++ + K + G +K KP+E +RK ED +D
Sbjct: 1328 SEESKKPRYRHRLLRHKLTVSDGESGEEKK--TKPKEHKEVKGRNRRKVSSEDSEDSDFQ 1385
Query: 654 KKG-KKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKK 712
+ G + ++ E+EQ ++ + +E +R+ +Q++ K+ ++ E + +N++ +++
Sbjct: 1386 ESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKK-KRRRIKVQEDSSSENKSNSEE 1444
Query: 713 KTNDSEGQKHKRKKFRQKQ 731
+ + E ++ + ++ +++
Sbjct: 1445 EEEEKEEEEEEEEEEEEEE 1463
Score = 40.8 bits (94), Expect = 0.005
Identities = 49/223 (21%), Positives = 91/223 (40%), Gaps = 17/223 (7%)
Query: 483 PEAAQNNPGEEVTETAG-EGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQ 541
PE + G++ E G E +++ + E++ +S + L R K+ V
Sbjct: 1296 PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR-----HKLTVSDG 1350
Query: 542 FSGDD--LVPVEVSDLE-EELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIK 598
SG++ P E +++ S E+ E+ + Q E SE E+E A
Sbjct: 1351 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1410
Query: 599 ALDEKIAKYQ--KFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDV------DDR 650
L+E Y+ K + K ++ S+ E+ K EE+ + EE+ DD
Sbjct: 1411 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1470
Query: 651 APSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKK 693
KG+K+ + ++ + + AL +E RR +R ++
Sbjct: 1471 KSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERE 1513
Score = 31.6 bits (70), Expect = 2.7
Identities = 45/238 (18%), Positives = 99/238 (41%), Gaps = 22/238 (9%)
Query: 506 IKEETEENSHCDANT--EMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFS 563
+ E E++ H T ++Q L+ + + F K + + S DD + E++ S
Sbjct: 939 VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF 998
Query: 564 DEEEEEQEQQRDDAEESSSE-PEEENVGNDTKAVIKALD---EKIAKYQKFLDKAKAKK- 618
++ + EQQ + + + + + PE E + + K + + + + K +K DK KK
Sbjct: 999 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1058
Query: 619 ----FSAVRISKGLS----------EKIFAKPEEQRKTLEEDVDDRAP-SKKGKKRKAQR 663
++ KG S + + +++ K L + R S ++ + +
Sbjct: 1059 ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK 1118
Query: 664 EEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQK 721
E+ S+K + + +ERR ++ K++ + ++ NKKK + +K
Sbjct: 1119 EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKK 1176
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 50.1 bits (118), Expect = 7e-06
Identities = 71/316 (22%), Positives = 128/316 (40%), Gaps = 41/316 (12%)
Query: 368 PSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAEDFLEKLAF 427
P+ DSET+ LK + + + P H + E +P + +S E + +
Sbjct: 168 PASDSETEDALKPQISDSESEEPPRHQASDSENEEPPK-PRMSDSESEELPKPQVSDSES 226
Query: 428 RTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFF-VKPPNAEPLVAPQLLPSSSLEVVPEAA 486
+ + + + + K ++D + P E L P++ S S + A
Sbjct: 227 EEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQA 286
Query: 487 QNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDD 546
++ EE+ + SES E ++ D+ TE +R +Q P+ D
Sbjct: 287 SDSENEELPKPRVSDSES---EGPQKGPASDSETEDA---SRHKQK-------PESDDDS 333
Query: 547 LVPVEVSDLEEELESF-------------SDEEEEEQEQQRDDAEESSSEPEEENVGNDT 593
+ D E + +SF SD EEEE ++Q+ D++E E EEE V
Sbjct: 334 DRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRK 393
Query: 594 KAVIKALDEKIAKYQKFLDKAKAKKFSAVR-ISKGLSEKIFAKPEEQRKTLEEDVDDRAP 652
AV+ +++ +KA AKK V S+ + K ++ KT+ D ++ A
Sbjct: 394 AAVLSDSEDE--------EKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEA- 444
Query: 653 SKKGKKRKAQREEEQE 668
GK+ ++ EE++
Sbjct: 445 ---GKELSDKKNEEKD 457
Score = 35.8 bits (81), Expect = 0.15
Identities = 56/261 (21%), Positives = 99/261 (37%), Gaps = 50/261 (19%)
Query: 475 PSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFG 534
P+S E+ E Q +P + +ET I E+EE A+ + + R +
Sbjct: 155 PASDSEI--EELQKSPASD-SETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDS 211
Query: 535 KINVVPQFSGDDLVPVEVSDLEEE---LESFSDEEEEEQEQQRDDAEESSSEPEEENVGN 591
+ +P+ +VSD E E SD E EE + R ES P + +
Sbjct: 212 ESEELPK--------PQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDS 263
Query: 592 DTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEK------IFAKPEEQRKTLEE 645
+ + + K RIS SE ++ EE K
Sbjct: 264 ENEELPKP-----------------------RISDSESEDPPRNQASDSENEELPKPRVS 300
Query: 646 DVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVK 705
D + P +KG ++ E+ H K P + +R + + + ++ H+
Sbjct: 301 DSESEGP-QKGPASDSETEDASRHKQK-PESDDDSDR-----ENKGEDTEMQNDSFHSDS 353
Query: 706 NRNRNKKKTNDSEGQKHKRKK 726
+ +R K ++DSE ++HK++K
Sbjct: 354 HMDRKKFHSSDSEEEEHKKQK 374
Score = 30.8 bits (68), Expect = 4.7
Identities = 44/199 (22%), Positives = 79/199 (39%), Gaps = 42/199 (21%)
Query: 486 AQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFG--------KIN 537
A ++ + V++ +G+ ++I + EE A E+ + FG + N
Sbjct: 417 ADDSDSDAVSDKSGKREKTIASDSEEE-----AGKELSDKKNEEKDLFGSDSESGNEEEN 471
Query: 538 VVPQFSGDDLVPVEVSDLEEELESFSDE--EEEEQEQQRDDAEESSSEPEEENVGNDTKA 595
++ G+ + EEE F+ E EEE+ E Q +AE+S S ++N+
Sbjct: 472 LIADIFGES-----GDEEEEEFTGFNQEDLEEEKGETQVKEAEDSDS---DDNI------ 517
Query: 596 VIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKK 655
K K+ FL + ++ K +S K + T D DD +
Sbjct: 518 -------KRGKHMDFLSDFE----MMLQRKKSMSGK--RRRNRDGGTFISDADDVVSAMI 564
Query: 656 GKKRKAQREEEQEHSNKAP 674
K +A E+ Q ++ K P
Sbjct: 565 VKMNEAAEEDRQLNNQKKP 583
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 50.1 bits (118), Expect = 7e-06
Identities = 44/220 (20%), Positives = 88/220 (40%), Gaps = 43/220 (19%)
Query: 554 DLEEELESFSDEEEEEQEQQRDDAEESSSEPEEEN---------------------VGND 592
+L ++ E +EE + QE++ +D E++ S EE+ + +
Sbjct: 780 ELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEE 839
Query: 593 TKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGL-----------SEKIFAKPEEQRK 641
+A ++ ++ K+ K+Q L+ K K + + EK + E+ K
Sbjct: 840 KRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDK 899
Query: 642 TLEEDVDDRAPSKKGKKR--KAQREEEQEHSNKAPRALTSKERR---------RAVRQQR 690
+E ++ R+ KK K ++E ++ HS + +S RR R+ R +R
Sbjct: 900 KDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSER 959
Query: 691 PKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQK 730
K R +H R+ +KK G + ++ R +
Sbjct: 960 SHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSR 999
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 49.7 bits (117), Expect = 1e-05
Identities = 42/178 (23%), Positives = 82/178 (46%), Gaps = 14/178 (7%)
Query: 561 SFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFS 620
S SD + Q D+ +S S EE++ K K + K++K +K K KK
Sbjct: 200 SSSDSDSSSDSQSSSDSSDSESATEEKS-----KKRKKKHRKNSRKHKK--EKKKRKKSK 252
Query: 621 AVRISKGLSEKIFAKPE-----EQRKTLEED--VDDRAPSKKGKKRKAQREEEQEHSNKA 673
S+ +E + A+P+ E+ + E+ + ++P K +K + RE E+E
Sbjct: 253 KSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNP 312
Query: 674 PRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
P + + +RR + + +K+ R + +R+R++ + SE H R++ ++ Q
Sbjct: 313 PNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQ 370
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/123 (22%), Positives = 58/123 (47%), Gaps = 9/123 (7%)
Query: 611 LDKAKAKKFSAVRIS--KGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQE 668
L++ K + S VR+ K + ++ ++ E+ V D + K + + E++ +
Sbjct: 388 LNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDK 447
Query: 669 HSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFR 728
+ NK + SK R ++ + + K E + NRN K+ + S+G+ H+ K +
Sbjct: 448 YKNKVKKRAKSKSRSKSKEKSKSK-------ERDSKHNRNEEKRMRSRSKGRDHENVKEK 500
Query: 729 QKQ 731
+KQ
Sbjct: 501 EKQ 503
Score = 40.0 bits (92), Expect = 0.008
Identities = 37/167 (22%), Positives = 78/167 (46%), Gaps = 12/167 (7%)
Query: 566 EEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRIS 625
++ + + R ++E S E ++ N + ++++ K D K+ S
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSKHNRNE------EKRMRSRSKGRDHENVKEKEKQSDS 506
Query: 626 KGLSEKIFAKPEEQRKTLEEDVDDRAPSK-KGKKRKAQREEEQEHSNKAPRALTSKERRR 684
KG ++ ++ +E+ K LE ++ SK K K R+AQ + K + S+ R R
Sbjct: 507 KGKDQER-SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRER 565
Query: 685 AVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+ + R ++V R TH+ ++R+R+K+ E + +R + R ++
Sbjct: 566 SRSRDRSRRVRSR---THD-RDRSRSKEYHRYREQEYRRRGRSRSRE 608
Score = 36.2 bits (82), Expect = 0.11
Identities = 36/185 (19%), Positives = 75/185 (40%), Gaps = 19/185 (10%)
Query: 544 GDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDT-------KAV 596
G D + ++LES S+E + + +++D +S S + G + ++
Sbjct: 508 GKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSR 567
Query: 597 IKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKG 656
+ ++ D++++K++ R E+ + + R R+ SK
Sbjct: 568 SRDRSRRVRSRTHDRDRSRSKEYHRYR------EQEYRRRGRSRSRERRTPPGRSRSKDR 621
Query: 657 KKRK-----AQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNK 711
++R+ ++REE Q + R SK R + K++ + + HN N +R K
Sbjct: 622 RRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRD-HNSSNNSREK 680
Query: 712 KKTND 716
K D
Sbjct: 681 KADRD 685
>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
Length = 439
Score = 49.3 bits (116), Expect = 1e-05
Identities = 44/207 (21%), Positives = 95/207 (45%), Gaps = 22/207 (10%)
Query: 535 KINVVPQFSGD--DLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGND 592
K+ V SG D P+E SD E+E F + +E++ + + E+SSS+P + N
Sbjct: 33 KVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQN- 91
Query: 593 TKAVIKALDEKIAKYQKFLD-KAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRA 651
+ + ++E++A+++K ++ + + S V E+ + EE EE++DD
Sbjct: 92 --RISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEE-----EEEIDD-- 142
Query: 652 PSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHN-------- 703
+ ++R R+ QE N+ + ++ R+ + + Y ++ +
Sbjct: 143 -EEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKP 201
Query: 704 VKNRNRNKKKTNDSEGQKHKRKKFRQK 730
V R +++ + E + K+K+ Q+
Sbjct: 202 VFIRKKDRVTVQEREAEALKQKELEQE 228
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 48.5 bits (114), Expect = 2e-05
Identities = 54/246 (21%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 500 EGSESIIKEETEENSHCDANTEMQQIL-TRVRQNFGKINVV-PQFSGDDLVPVEVSDLEE 557
E + IKE + NS ++ E + L +R Q + N P + E D
Sbjct: 168 EDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGN----EDDDASF 223
Query: 558 ELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEK----IAKYQKFLDK 613
++++ + ++ E++E++R +E KA ++ L EK K + K
Sbjct: 224 KIKTVAQKKAEKKERERKKRDEE-------------KAKLRKLKEKEELETGKKDQSKQK 270
Query: 614 AKAKKFS--AVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGK---KRKAQREEEQE 668
+KF V+ + + EE+ +T DD KK K K+K ++EE+++
Sbjct: 271 ESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEK 330
Query: 669 HSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNR---NKKKTNDSEGQKHKRK 725
K P T K + A+ + + ++ + E +K +K+ E +K +RK
Sbjct: 331 EKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERK 390
Query: 726 KFRQKQ 731
K ++K+
Sbjct: 391 KQKEKE 396
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/250 (18%), Positives = 104/250 (41%), Gaps = 18/250 (7%)
Query: 482 VPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQ 541
+ AQ ++ E E + +E + + Q ++ F + V +
Sbjct: 225 IKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSK 284
Query: 542 FSGDD-LVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKAL 600
+ D ++P E + D E +++++ + + E E+E +KA +KA+
Sbjct: 285 VTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAM 344
Query: 601 DEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRK 660
E +AK ++ ++ + K+ RI + E++ AK +E ++R +K +++K
Sbjct: 345 QEALAKLKE--EEERQKREEEERIKR--LEELEAKRKE---------EERLEQEKRERKK 391
Query: 661 AQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQ 720
+ +E +E K + LT +R R + K+ + V+ +++ +
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKL----LQAQGVEVPSKDSLPKKRPIYE 447
Query: 721 KHKRKKFRQK 730
KRKK Q+
Sbjct: 448 DKKRKKIPQQ 457
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 16/135 (11%)
Query: 543 SGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDE 602
S ++ VE + + E++ +EEEEE+E++ +D E SE EEE G + DE
Sbjct: 511 SDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEE---SEEEEEEEGESEGSEGDEEDE 567
Query: 603 KIAKYQ---KFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKR 659
K++ + K LDK +K+ S S+ + ++ +T EE D+A + K+R
Sbjct: 568 KVSDEKDSGKTLDKKPSKEMS--------SDSEYDSDDD--RTKEERAYDKAKRRIEKRR 617
Query: 660 KAQREEEQEHSNKAP 674
+ +AP
Sbjct: 618 LEHSKNVNTEKLRAP 632
Score = 32.3 bits (72), Expect = 1.6
Identities = 47/208 (22%), Positives = 82/208 (39%), Gaps = 34/208 (16%)
Query: 550 VEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIA---- 605
+E + +E E + ++++E+++ D +E E E + + + IKA E +A
Sbjct: 26 IEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQG-IKADRETVAVKPT 84
Query: 606 --KYQKFLDKAKAKKF------------SAVRISKGLSEKIFAKPEEQRKTLEEDVDDRA 651
++F K K KK S K K AKP+ + + +D DD
Sbjct: 85 ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFN 144
Query: 652 PSKKGKKRKAQR--------EEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHN 703
K K KAQ+ EE++++S K KER R + ++
Sbjct: 145 KLPKKAKGKAQKSNKKWDGSEEDEDNSKKI------KERSRINSSGESGDESDEFLQSRK 198
Query: 704 VKNRN-RNKKKTNDSEGQKHKRKKFRQK 730
+ +N +NK N G + F+ K
Sbjct: 199 GQKKNQKNKPGPNIESGNEDDDASFKIK 226
Score = 32.0 bits (71), Expect = 2.1
Identities = 31/140 (22%), Positives = 59/140 (42%), Gaps = 4/140 (2%)
Query: 552 VSDLEEELESFSDEEEEEQEQQ-RDDAEESSSEPEEENV-GNDTKAVIKALDEKIAKYQK 609
V + EE EEEE+ E DD E +S+ E E V GN +K E+ + ++
Sbjct: 480 VPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEE 539
Query: 610 FLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEH 669
++ + ++ +G SE E+++ + E+D K K+ + E + +
Sbjct: 540 --EEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDD 597
Query: 670 SNKAPRALTSKERRRAVRQQ 689
K +RR +++
Sbjct: 598 DRTKEERAYDKAKRRIEKRR 617
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 48.5 bits (114), Expect = 2e-05
Identities = 37/187 (19%), Positives = 88/187 (47%), Gaps = 7/187 (3%)
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDT---KAVIKALDEKIAKY 607
+V E +E +E++++ EQ+ +E + + +EE + + KA K ++E A+
Sbjct: 580 KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 639
Query: 608 QKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVD-DRAPSKKGKKRKAQREEE 666
++ + + + + E + K EE+++ L + + R ++ ++R+ Q E
Sbjct: 640 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 699
Query: 667 QEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRN---RNKKKTNDSEGQKHK 723
QE + R +E+ R + +Q ++ R ++ R R +K+ E ++ K
Sbjct: 700 QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 759
Query: 724 RKKFRQK 730
+K+ +Q+
Sbjct: 760 KKEEQQR 766
Score = 47.8 bits (112), Expect = 4e-05
Identities = 44/191 (23%), Positives = 85/191 (44%), Gaps = 22/191 (11%)
Query: 557 EELESFSDEEEEEQ-------EQQRDDAEESSSEPEE---------ENVGNDTKAVIKAL 600
+ LE+ +EE EQ E +R EE + EE E V + K +
Sbjct: 540 QRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 599
Query: 601 DEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRK 660
++K A+ + +KAK ++ + + K + K + E +RK EE R ++ ++R+
Sbjct: 600 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659
Query: 661 AQ------REEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKT 714
Q +EEEQE KA A E+R R+++ ++ R + + R +++
Sbjct: 660 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 719
Query: 715 NDSEGQKHKRK 725
+ E ++ + +
Sbjct: 720 AEQERRREQER 730
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/240 (19%), Positives = 104/240 (43%), Gaps = 20/240 (8%)
Query: 500 EGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKI----NVVPQFSGDDLVPVE--VS 553
E +E + +++ EE D ++++ + + K+ V Q + +E +
Sbjct: 549 EEAEQLRRQKVEE----DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 604
Query: 554 DLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKAL--DEKIAKYQKFL 611
++E+ E +E E++ ++ A + E E + ++ L +E+ ++Q+ L
Sbjct: 605 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 664
Query: 612 DKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSN 671
K K ++ R+ K K A+ EQ + +E R ++ ++R+ Q EQE
Sbjct: 665 QKKKEEEQE--RLRKAAEAKRLAEQREQERREQER---REQERREQERREQERREQERQL 719
Query: 672 KAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+ER +A R+ + ++ +R + + KKK E Q+ ++ +++Q
Sbjct: 720 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK---EEQQRLAERQLQEEQ 776
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 48.5 bits (114), Expect = 2e-05
Identities = 37/187 (19%), Positives = 88/187 (47%), Gaps = 7/187 (3%)
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDT---KAVIKALDEKIAKY 607
+V E +E +E++++ EQ+ +E + + +EE + + KA K ++E A+
Sbjct: 576 KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 635
Query: 608 QKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVD-DRAPSKKGKKRKAQREEE 666
++ + + + + E + K EE+++ L + + R ++ ++R+ Q E
Sbjct: 636 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 695
Query: 667 QEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRN---RNKKKTNDSEGQKHK 723
QE + R +E+ R + +Q ++ R ++ R R +K+ E ++ K
Sbjct: 696 QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 755
Query: 724 RKKFRQK 730
+K+ +Q+
Sbjct: 756 KKEEQQR 762
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/202 (23%), Positives = 90/202 (44%), Gaps = 25/202 (12%)
Query: 549 PVEVSDLEEE---LESFSDEEEEEQ-------EQQRDDAEESSSEPEE---------ENV 589
P+ + E+E LE+ +EE EQ E +R EE + EE E V
Sbjct: 525 PLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERV 584
Query: 590 GNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDD 649
+ K +++K A+ + +KAK ++ + + K + K + E +RK EE
Sbjct: 585 EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Query: 650 RAPSKKGKKRKAQ------REEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHN 703
R ++ ++R+ Q +EEEQE KA A E+R R+++ ++ R +
Sbjct: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR 704
Query: 704 VKNRNRNKKKTNDSEGQKHKRK 725
+ R +++ + E ++ + +
Sbjct: 705 EQERREQERQLAEQERRREQER 726
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/240 (19%), Positives = 104/240 (43%), Gaps = 20/240 (8%)
Query: 500 EGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKI----NVVPQFSGDDLVPVE--VS 553
E +E + +++ EE D ++++ + + K+ V Q + +E +
Sbjct: 545 EEAEQLRRQKVEE----DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 600
Query: 554 DLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKAL--DEKIAKYQKFL 611
++E+ E +E E++ ++ A + E E + ++ L +E+ ++Q+ L
Sbjct: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 660
Query: 612 DKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSN 671
K K ++ R+ K K A+ EQ + +E R ++ ++R+ Q EQE
Sbjct: 661 QKKKEEEQE--RLRKAAEAKRLAEQREQERREQER---REQERREQERREQERREQERQL 715
Query: 672 KAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+ER +A R+ + ++ +R + + KKK E Q+ ++ +++Q
Sbjct: 716 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK---EEQQRLAERQLQEEQ 772
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 47.8 bits (112), Expect = 4e-05
Identities = 23/96 (23%), Positives = 50/96 (52%)
Query: 635 KPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKV 694
K +E+RK ++ + + +K+ +KRK + EEE++ K + +ER ++ +K
Sbjct: 28 KRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE 87
Query: 695 GVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQK 730
E K + + ++K + E +K +R+K ++K
Sbjct: 88 EEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 47.0 bits (110), Expect = 6e-05
Identities = 38/149 (25%), Positives = 66/149 (44%), Gaps = 26/149 (17%)
Query: 565 EEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRI 624
+++++++++ ++ EE+ EEE K K + +K +K K KK
Sbjct: 1 KKKKKKKKETEETEETEETEEEEE---------KEGKRKEKRKEKRKEKEKKKK------ 45
Query: 625 SKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRR 684
K E+RK EE+ R +K KK + +REEE+E + +E RR
Sbjct: 46 ---------TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRR 96
Query: 685 AVRQQRPKKVGVRYYETHNVKNRNRNKKK 713
R+++ K+ E K R + KKK
Sbjct: 97 --RKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 44.7 bits (104), Expect = 3e-04
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 13/128 (10%)
Query: 554 DLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDK 613
+ EE E+ EEEEE+E +R + + + +E+ +K + +K +K
Sbjct: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKK-------------KKTKETEKRKEK 55
Query: 614 AKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKA 673
+ +K + K E+ + EE+ + +E+ + ++ KK+K +R+EE+E K
Sbjct: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Query: 674 PRALTSKE 681
R T K+
Sbjct: 116 RRRKTKKK 123
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 637 EEQRKTLEEDVDDRAPSKKGKKRKAQREE-EQEHSNKAPRALTSKERRRAVRQQRPKKVG 695
EE +T E + ++ K+ +KRK +R+E E++ K KE R+++ KK
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70
Query: 696 VRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+ K++ EG++ K+KK R+++
Sbjct: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106
Score = 38.9 bits (89), Expect = 0.017
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 10/78 (12%)
Query: 654 KKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKK 713
KK KK + EE +E + + KE+R+ R+++ KK K + K+K
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK----------KTKETEKRK 53
Query: 714 TNDSEGQKHKRKKFRQKQ 731
+ E +K KRK+ ++K+
Sbjct: 54 EKEEEEKKRKRKRKKKKE 71
Score = 37.4 bits (85), Expect = 0.050
Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 7/122 (5%)
Query: 613 KAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKA----QREEEQE 668
K K KK ++ E + EE+++ ++ +K KK+K +R+E++E
Sbjct: 1 KKKKKKKKETEETEETEE---TEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57
Query: 669 HSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFR 728
K R K+ ++ ++ + E R + KKK E ++ K+KK R
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117
Query: 729 QK 730
+K
Sbjct: 118 RK 119
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 47.8 bits (112), Expect = 4e-05
Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKF 610
E L EE ES +EEE E+E++ +D ++ S+ +E+ +D + EK
Sbjct: 1037 EKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEK------- 1089
Query: 611 LDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHS 670
D+ + + V I +E + + E + S + ++ REEE+E
Sbjct: 1090 -DEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEE 1148
Query: 671 NK 672
+
Sbjct: 1149 EE 1150
Score = 30.8 bits (68), Expect = 4.7
Identities = 23/109 (21%), Positives = 45/109 (41%)
Query: 484 EAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFS 543
E ++ ++ E+ + ++ + E +E++ E I+T +
Sbjct: 1061 EDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSE 1120
Query: 544 GDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGND 592
+ S E+E E + EEEEE+E++ AEES + E+ D
Sbjct: 1121 FESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQD 1169
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 47.8 bits (112), Expect = 4e-05
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 32/218 (14%)
Query: 458 FFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCD 517
+F++ ++ + PQ+L S ++VP + + PG + + + G G + +KE + +
Sbjct: 338 YFIQQKVSKGIDPPQVL---SPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDIS---- 390
Query: 518 ANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDA 577
Q+I R+ + D+ E+ E+ + E QE Q D
Sbjct: 391 -----QEIAQLQREKYSL----------------EQDIREKEEAIRQKTSEVQELQNDLD 429
Query: 578 EESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPE 637
E+SS E E D + + +D++ AK + L + K ++ L +I +
Sbjct: 430 RETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQI----Q 485
Query: 638 EQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPR 675
Q L+ DD +K R Q E + E S +A R
Sbjct: 486 SQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGR 523
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 47.4 bits (111), Expect = 5e-05
Identities = 45/181 (24%), Positives = 83/181 (45%), Gaps = 19/181 (10%)
Query: 550 VEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQK 609
+EV + +E + +EEEEE+E+ D ESS E + E+ DEK A YQ
Sbjct: 586 LEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSES------------DEK-ANYQA 632
Query: 610 FLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEH 669
L A + I + L +++ +++ +TL++ +++ + K R Q E +Q
Sbjct: 633 DL----ANITCEIAIKQKLIDEL-ENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVL 687
Query: 670 SNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKR-KKFR 728
N S+E+ + VR + KK+ E ++ + + ++ Q K+ KK +
Sbjct: 688 QNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQ 747
Query: 729 Q 729
Q
Sbjct: 748 Q 748
Score = 35.8 bits (81), Expect = 0.15
Identities = 43/234 (18%), Positives = 97/234 (41%), Gaps = 30/234 (12%)
Query: 492 EEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVE 551
EE E +G ES + ++E + + ++ I + I+ E
Sbjct: 604 EEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLID-------------E 650
Query: 552 VSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEE--ENVGN-------DTKAVIKALDE 602
+ + ++ L++ + EE+ + ++ E ++ +N+G+ K V ++
Sbjct: 651 LENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEK 710
Query: 603 KIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQ 662
K+ K L + +A + R+ K S+ E+Q K L++DV + KK K R +
Sbjct: 711 KLQAMNKELQRLQAAQKEHARLLKNQSQY-----EKQLKKLQQDVME---MKKTKVRLMK 762
Query: 663 REEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTND 716
+ +E++ + + ++E + + QR + +R E ++KT +
Sbjct: 763 QMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEE 816
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 47.0 bits (110), Expect = 6e-05
Identities = 40/186 (21%), Positives = 79/186 (42%), Gaps = 16/186 (8%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
EEE D+E ++QR D + EE T AL E++ K Q+ L + +
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPR 675
+ + + EK + +E++ EE + ++R+ +R +E+E + +
Sbjct: 911 EE------LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
Query: 676 ALTSKE----------RRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRK 725
L KE RRR R+++ ++ E + R K++ + E Q K+
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
Query: 726 KFRQKQ 731
+ +Q++
Sbjct: 1025 ELQQEE 1030
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/179 (21%), Positives = 84/179 (46%), Gaps = 17/179 (9%)
Query: 564 DEEEEEQEQQRDDAEESSSE-PEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAV 622
+++E ++EQ+R ++ PEEE + + + K D K + ++ L + + +K
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 623 RISKGL--SEKIFAKPEEQ--------RKTLEEDVDDRAPSKK--GKKRKAQREEEQEHS 670
+ E++ + EEQ RK EE++ + +K ++++ +R+E +
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392
Query: 671 NKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQ 729
K + L +ER + +RQ R +K + E +R +K + E Q ++++ R+
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRK----FREEEQQLSRQERDRKFREEEQQVRRQERERK 1447
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/188 (17%), Positives = 83/188 (44%), Gaps = 25/188 (13%)
Query: 558 ELESFSDEEE--------------EEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEK 603
E E F DEE+ EE++QQR + ++ + EEE + V++ +EK
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 604 IAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQR 663
+ + + + ++ E+ K E Q E +++ + ++++ +R
Sbjct: 260 LQEEEPQRQRELQEE-----------EEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 664 EEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHK 723
++E+E + +ERR ++R +++ E + R +++ + + ++ +
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 724 RKKFRQKQ 731
++ R++Q
Sbjct: 369 EEERREQQ 376
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/176 (23%), Positives = 76/176 (43%), Gaps = 13/176 (7%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
E++L D + E+EQQ E EEE + K L+E+ Q+ +
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE----QQLRQERH 1460
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPR 675
K ++ + E+ + E RK LEE+ R + K R EQE ++ P
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFR------EQELRSQEPE 1514
Query: 676 ALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+E ++ RQQR +K E ++ + R +++ D + + + ++ RQ++
Sbjct: 1515 RKFLEEEQQLHRQQRQRKF---LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
Score = 43.5 bits (101), Expect = 7e-04
Identities = 42/177 (23%), Positives = 79/177 (44%), Gaps = 27/177 (15%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
EEEL+ E+ QEQ+R EE + EEE + + + + E+ +Y+K DK
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK-RRRQERERQYRK--DKKL 966
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEE-QEHSNKAP 674
+K E++ + E+R+ E +++K + EEE Q+ +
Sbjct: 967 QQK----------EEQLLGEEPEKRRRQE------------REKKYREEEELQQEEEQLL 1004
Query: 675 RALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
R K RR+ +Q KK ++ E + R K++ + E Q + ++ +Q++
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQ-QEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/194 (22%), Positives = 91/194 (46%), Gaps = 19/194 (9%)
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESS--SEPEEENVGNDTKAVIKALDEKIAKYQ 608
+V E E + +E++ QE+ R EE E EE+ + + K L+E+ Q
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR-KFLEEE----Q 1492
Query: 609 KFLDKAKAKKFSAVRISKGLSEKIFAKPEEQ-------RKTLEEDVDDRAPSKKGKKRKA 661
+ + + +KF + E+ F + E+Q RK L+E+ R + ++R+
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 662 Q----REEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDS 717
+ REEEQ + + L+ +ER R R + +KV + E +++ + +++
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEE-QKVRRQEQERKFMEDEQQLRRQEGQQ 1611
Query: 718 EGQKHKRKKFRQKQ 731
+ ++ + +KFR+ +
Sbjct: 1612 QLRQERDRKFREDE 1625
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/180 (21%), Positives = 80/180 (44%), Gaps = 8/180 (4%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFL---- 611
E + EEEEE+ +QR E E+E + + + + +I K+Q L
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 612 DKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSN 671
D ++K +S R +G + + EE+R+ E ++ + ++ R+ Q EE++
Sbjct: 713 DARQSKVYSRPRKQEGQRRR--QEQEEKRRRRESEL--QWQEEERAHRQQQEEEQRRDFT 768
Query: 672 KAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+A ER R RP R + + + R ++ + E ++ +R++ R+++
Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Score = 41.6 bits (96), Expect = 0.003
Identities = 54/285 (18%), Positives = 120/285 (42%), Gaps = 22/285 (7%)
Query: 452 QRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETE 511
+R R + KP E L Q +++ E + EE + + E +EE +
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQ-------QLLQEEEEELQREEREKRRRQEQERQYREEEQ 935
Query: 512 ENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQE 571
E +Q+L R+ + Q+ D ++ EE+L E+ QE
Sbjct: 936 ------LQQEEEQLLREEREKRRRQERERQYRKDK----KLQQKEEQLLGEEPEKRRRQE 985
Query: 572 QQRDDAEESSSEPEEENVGNDTKAVIKALD-EKIAKYQKFLDKAKAKKFSAVRISKGLSE 630
+++ EE + EEE + + + + + E+ + + L + + + R + L E
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Query: 631 KIFAKPEEQRKTLEEDV---DDRAPSKKGK-KRKAQREEEQEHSNKAPRALTSKERRRAV 686
+ EE+ EE+ ++R ++ + +R+ ++EEE + + ++RRR
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE 1105
Query: 687 RQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
R+++ ++ E + R K++ + E Q + ++ +Q++
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Score = 40.8 bits (94), Expect = 0.005
Identities = 52/268 (19%), Positives = 104/268 (38%), Gaps = 46/268 (17%)
Query: 496 ETAGEGSESIIKEETEENSH------CDANTEMQQ----ILTRVRQNFGKINVVPQFSGD 545
E + E +++EE E+ C E+QQ +L R+ + + Q+ +
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 546 DLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIA 605
+ EV EE+L E+ QE +R EE + EEE + + + + E+
Sbjct: 1144 E----EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
Query: 606 KYQKFLDKAKAK-------------------KFSAVRISKGLSEKIFAKPEEQ---RKTL 643
+ ++ L + K K K +AVR K++ K E R+
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR-----DNKVYCKGRENEQFRQLE 1254
Query: 644 EEDVDDRAPSKK-----GKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRY 698
+ + DR + G++++ RE+E+ + R +E+ Q+ K+ +
Sbjct: 1255 DSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS 1314
Query: 699 YETHNVKNRNRNKKKTNDSEGQKHKRKK 726
E + R +K+ +K + ++
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEE 1342
Score = 39.3 bits (90), Expect = 0.013
Identities = 30/182 (16%), Positives = 85/182 (46%), Gaps = 7/182 (3%)
Query: 555 LEEELESFSDEEEEEQEQQRDDAEESSSE-----PEEENVGNDTKAVIKALDEKIAKYQK 609
L+ E E+ E+E ++Q + D EE E EEE + + E+ + ++
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 610 FLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEH 669
L + + ++ R+ +++ + EE+R+ L + +++ ++ ++++ +RE+E+
Sbjct: 518 RLKRQEEEERLQQRLRS--EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 670 SNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQ 729
R +++R Q+ + ++ E ++ R +++ E ++ +R++ +
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635
Query: 730 KQ 731
+
Sbjct: 636 SE 637
Score = 39.3 bits (90), Expect = 0.013
Identities = 50/248 (20%), Positives = 102/248 (41%), Gaps = 22/248 (8%)
Query: 491 GEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPV 550
GEE + + E +EE E E +Q+L R+ + Q+ D
Sbjct: 975 GEEPEKRRRQEREKKYREEEE------LQQEEEQLLREEREKRRRQEWERQYRKKD---- 1024
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKA--LDEKIAKYQ 608
E+ EE+L E+ QE++R EE + EEE + + + + L+ + K +
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 609 KFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDV--DDRAPSKKGKKRKAQREEE 666
+ + + + + + EE+ + EE + ++R ++ + + REEE
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 667 --QEHSNKAPRALTSKERRRAVRQQRPKKVGVR------YYETHNVKNRNRNKKKTNDSE 718
Q+ + R K RR+ + +Q ++ ++ E + + R ++ + E
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEE 1204
Query: 719 GQKHKRKK 726
Q+ KRK+
Sbjct: 1205 LQRQKRKQ 1212
Score = 38.9 bits (89), Expect = 0.017
Identities = 36/180 (20%), Positives = 88/180 (48%), Gaps = 11/180 (6%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
E+EL+ EEEEQ Q+R+ A++ + EE+ + D + + K++ L++ +
Sbjct: 828 EKELQFL---EEEEQLQRRERAQQL--QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQR--EEEQEHSNKA 673
++ + L E++ + E+Q EE+ R +K ++++ +R EE++ +
Sbjct: 883 KRRRHTLYAKPALQEQL--RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
Query: 674 PRALTS--KERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+ L ++RRR R+++ +K + + K++ + E + + ++ +Q++
Sbjct: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
Score = 37.4 bits (85), Expect = 0.050
Identities = 33/183 (18%), Positives = 78/183 (42%), Gaps = 11/183 (6%)
Query: 555 LEEELESFSDEEEEEQ---EQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFL 611
LEEE E E+Q EQ+ + + EEE + ++ + E+ + ++ L
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 612 DKAKAKKFSAVRISKGLS-------EKIFAKPEEQR-KTLEEDVDDRAPSKKGKKRKAQR 663
+ + K+ R + L +++ + EE+R + L+ + ++R + ++ +
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 664 EEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHK 723
E+E+ + R +ERR+ + + ++ + + R + K + E + +
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 724 RKK 726
R K
Sbjct: 671 RLK 673
Score = 37.0 bits (84), Expect = 0.065
Identities = 34/169 (20%), Positives = 79/169 (46%), Gaps = 14/169 (8%)
Query: 555 LEEELESFSDEEEEEQEQQRD----DAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKF 610
LEEE EE++ + Q+RD + E+ E EE+ + + +E++ + ++
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Query: 611 LDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHS 670
++ R + E++ + +EQR E D RA + + K++REE++
Sbjct: 1810 QQLRPQQRDGKYRWEE---EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ 1866
Query: 671 NKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEG 719
+ +++RR R+++ ++ +R + ++R + K+ + +G
Sbjct: 1867 EE-------EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
Score = 35.4 bits (80), Expect = 0.19
Identities = 38/207 (18%), Positives = 88/207 (42%), Gaps = 30/207 (14%)
Query: 555 LEEELESFSDEEEEEQEQQRDDAEESSSEPE-------------------EENVGNDTKA 595
LEEE ++ +EQE++ + EE S + E E + +A
Sbjct: 129 LEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRA 188
Query: 596 VIKALDE-KIAKYQKFLDKAKAKKFSAVRI-SKGLSEKIFAKPEEQRKTLEEDVDD---- 649
+ L K + ++F D+ + ++ + + KG EK + E Q + +E+ +
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248
Query: 650 -----RAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNV 704
R +K ++ + QR+ E + + R L +E RR +++ ++ +R +
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 705 KNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
K +++ + Q+ +R++ +++
Sbjct: 309 KQEEERREQQEERREQQERREQQEERR 335
Score = 32.7 bits (73), Expect = 1.2
Identities = 29/178 (16%), Positives = 75/178 (42%), Gaps = 7/178 (3%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
EE L+ E++ + +Q + E+ EE+ + + + +++ + Q + +
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQR-----EEEQEHS 670
++ R + E+ + E +R EE + R ++ ++ + Q+ E+E+
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 671 NKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFR 728
+ R + +R R++ +++ R H + R ++ + + Q +R K R
Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQRLKREH--EEERREQELAEEEQEQARERIKSR 700
Score = 32.3 bits (72), Expect = 1.6
Identities = 44/211 (20%), Positives = 94/211 (44%), Gaps = 17/211 (8%)
Query: 484 EAAQNNPGEEVTETAGEGSESII-KEETEENSHCDANTEMQQILTRVRQNFGKINVVPQF 542
E + EE E A E +S I K + + S DA ++ +R R+ G+ Q
Sbjct: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR--QSKVYSRPRKQEGQRRRQEQ- 735
Query: 543 SGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDE 602
++ S+L+ + E + +++E+EQ+RD + +E + E A ++
Sbjct: 736 --EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793
Query: 603 KIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQ 662
+ + + + + ++F K + + E++ + LEE+ + ++ +AQ
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE------EQLQRRERAQ 847
Query: 663 REEEQEHSNKAPRALTSKERRRAVRQQRPKK 693
+ +E+E + +ERRR+ Q+R +K
Sbjct: 848 QLQEEEDGLQE-----DQERRRSQEQRRDQK 873
Score = 32.0 bits (71), Expect = 2.1
Identities = 40/185 (21%), Positives = 74/185 (40%), Gaps = 17/185 (9%)
Query: 556 EEELESFSDEEE-EEQEQQRDDAEESSSEPEEENVG-----NDTKAVIKALDEKIAKYQK 609
EE+L +++E+ QE+ R EE PE E D K + + + Q+
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 610 FLDKAKAKKFSAVRISKGLSEKIFAKP---------EEQRKTLEEDVDDRAPSKKGKKRK 660
+ +KF + E+ +P EE++ LEE + + R
Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRA 1847
Query: 661 AQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYY-ETHNVKNRNRNKKKTNDSEG 719
++ QE S + + L +E ++ RQ+R +K+ + + R+R + EG
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKR-RQERERKLREEHIRRQQKEEQRHRQVGEIKSQEG 1906
Query: 720 QKHKR 724
+ H R
Sbjct: 1907 KGHGR 1911
Score = 31.6 bits (70), Expect = 2.7
Identities = 38/257 (14%), Positives = 111/257 (43%), Gaps = 23/257 (8%)
Query: 492 EEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVE 551
EE + E + + +EE EE T +++ ++++ + Q + L +E
Sbjct: 224 EEKQQQRRERQDRVFQEE-EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 552 VSDLEEELESFSDEEEE---------EQEQQRDDAEESSSEPEEENVGNDTKAVIKALDE 602
+L E + +++ +QE++R + +E E +E + + + E
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 603 KIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQ 662
+ + ++ L + + ++ R + L + + EQ+ E+ + ++ ++ + +
Sbjct: 343 QEERREQQLRREQEEE----RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 663 REEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKK--------- 713
++ +E + + L +++ R +Q R ++ R+ + H + R + K+
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 714 TNDSEGQKHKRKKFRQK 730
+ E ++H++++ +Q+
Sbjct: 459 KREEETERHEQERRKQQ 475
Score = 31.6 bits (70), Expect = 2.7
Identities = 31/191 (16%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKAL----------DEKIA 605
E++L +EE EQ+ +R+ + E + + + ++++
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 606 KYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREE 665
+ Q+ + + ++ + +++ + EE+R L+ + + ++ +K++ +R++
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 666 EQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTN-----DSEGQ 720
E+E + R L +E R +Q+R ++ R E + R +++ SE Q
Sbjct: 481 EEE---RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
Query: 721 KHKRKKFRQKQ 731
+ ++ R++Q
Sbjct: 538 LRREQEERREQ 548
Score = 31.6 bits (70), Expect = 2.7
Identities = 36/183 (19%), Positives = 81/183 (44%), Gaps = 21/183 (11%)
Query: 556 EEELESFSDEE---EEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDE--KIAKYQKF 610
E+EL S E EEEQ+ R + + EE+ + + + D K + ++
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQ-EEQQLRRQERGQQRRQDRDRKFREEEQL 1563
Query: 611 LDKAKAKKFSAVRISKG--LSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQE 668
+ + ++ S + L E+ + E++RK +E D ++ + ++ R+E
Sbjct: 1564 RQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME----DEQQLRRQEGQQQLRQERDR 1619
Query: 669 HSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFR 728
+ + L +E ++ RQ+R +K E ++ + R ++ +D + +KFR
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKF---LEEEPQLRRQEREQQLRHDRD------RKFR 1670
Query: 729 QKQ 731
+++
Sbjct: 1671 EEE 1673
Score = 31.6 bits (70), Expect = 2.7
Identities = 32/187 (17%), Positives = 85/187 (45%), Gaps = 15/187 (8%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSS----EPEEENVGNDTKAVIKALDEKIAKYQKFL 611
E+ L+ +++ QE+ R EE E E + + + + + L+ K + ++
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Query: 612 DKAKAKKFSAVRISKGLSEKIFAKPE---EQRKTLEEDVDDRAPSKKGKKRKAQREEEQE 668
+ + ++ + + E+ +PE +Q + E D ++ ++ + +REE+Q
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD----RKFREEEQLRQEREEQQL 1788
Query: 669 HSNKAPRALTSKERRRAVRQQ---RPKKVGVRY-YETHNVKNRNRNKKKTNDSEGQKHKR 724
S ++ R +E+ R R++ RP++ +Y +E ++ + ++ + + Q
Sbjct: 1789 RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE 1848
Query: 725 KKFRQKQ 731
++F ++
Sbjct: 1849 EQFATQE 1855
Score = 31.2 bits (69), Expect = 3.6
Identities = 29/180 (16%), Positives = 79/180 (43%), Gaps = 4/180 (2%)
Query: 556 EEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAK 615
E + +EEEE+ QQR +E+ +EE K + E+ + Q+ + +
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 616 AKKFSAVRISKGLSEKIFAKPEEQR---KTLEEDVDDRAPSKKGKKR-KAQREEEQEHSN 671
++ ++ + ++ + +E+R + E+V+ ++ ++R K + EE+
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632
Query: 672 KAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKHKRKKFRQKQ 731
+ R++ +R+++ ++ R + + K+ ++ E ++ + + Q+Q
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 46.6 bits (109), Expect = 8e-05
Identities = 45/165 (27%), Positives = 80/165 (48%), Gaps = 17/165 (10%)
Query: 563 SDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQK--FLDKAKAKKFS 620
SDEE E+ E+Q ++ EE+ EEE V + K K KI + +K F D K ++
Sbjct: 2 SDEEVEQVEEQYEEEEEAQ---EEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 58
Query: 621 AVRISKGLSEKIF---AKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRAL 677
+ + L + F K EE+ L+E ++ R +++ ++++ + E+E+E N+
Sbjct: 59 DLMELQALIDSHFEARKKEEEELVALKERIEKRR-AERAEQQRIRAEKERERQNRLAEEK 117
Query: 678 TSKE----RRRAVRQQRPKK----VGVRYYETHNVKNRNRNKKKT 714
+E +RRA + KK +G Y ++ R KK+T
Sbjct: 118 ARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQT 162
Score = 36.2 bits (82), Expect = 0.11
Identities = 47/216 (21%), Positives = 91/216 (42%), Gaps = 41/216 (18%)
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESSSEP---EEENVGNDT-------------K 594
EV +EE+ E + +EEE+ Q+ + + P E E V D +
Sbjct: 5 EVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQ 64
Query: 595 AVI-------KALDEKIAKYQKFLDKAKAKKFSAVRI-SKGLSEKIFAKPEEQRKTLEED 646
A+I K +E++ ++ ++K +A++ RI ++ E+ EE+ + EED
Sbjct: 65 ALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEED 124
Query: 647 VDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKN 706
RA KK+KA +S+ +A + +++ R+ + KK+ + N+ +
Sbjct: 125 AKRRAEDDL-KKKKALSSMGANYSSYLAKADQKRGKKQTAREMK-KKILAERRKPLNIDH 182
Query: 707 RNRNKKKTNDSE---------------GQKHKRKKF 727
+K + E G+K KR+K+
Sbjct: 183 LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKY 218
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 46.6 bits (109), Expect = 8e-05
Identities = 45/165 (27%), Positives = 80/165 (48%), Gaps = 17/165 (10%)
Query: 563 SDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQK--FLDKAKAKKFS 620
SDEE E+ E+Q ++ EE+ EEE V + K K KI + +K F D K ++
Sbjct: 2 SDEEVEQVEEQYEEEEEAQ---EEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 58
Query: 621 AVRISKGLSEKIF---AKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNKAPRAL 677
+ + L + F K EE+ L+E ++ R +++ ++++ + E+E+E N+
Sbjct: 59 DLMELQALIDSHFEARKKEEEELVALKERIEKRR-AERAEQQRIRAEKERERQNRLAEEK 117
Query: 678 TSKE----RRRAVRQQRPKK----VGVRYYETHNVKNRNRNKKKT 714
+E +RRA + KK +G Y ++ R KK+T
Sbjct: 118 ARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQT 162
Score = 36.2 bits (82), Expect = 0.11
Identities = 47/216 (21%), Positives = 91/216 (42%), Gaps = 41/216 (18%)
Query: 551 EVSDLEEELESFSDEEEEEQEQQRDDAEESSSEP---EEENVGNDT-------------K 594
EV +EE+ E + +EEE+ Q+ + + P E E V D +
Sbjct: 5 EVEQVEEQYEEEEEAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQ 64
Query: 595 AVI-------KALDEKIAKYQKFLDKAKAKKFSAVRI-SKGLSEKIFAKPEEQRKTLEED 646
A+I K +E++ ++ ++K +A++ RI ++ E+ EE+ + EED
Sbjct: 65 ALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEED 124
Query: 647 VDDRAPSKKGKKRKAQREEEQEHSNKAPRALTSKERRRAVRQQRPKKVGVRYYETHNVKN 706
RA KK+KA +S+ +A + +++ R+ + KK+ + N+ +
Sbjct: 125 AKRRAEDDL-KKKKALSSMGANYSSYLAKADQKRGKKQTAREMK-KKILAERRKPLNIDH 182
Query: 707 RNRNKKKTNDSE---------------GQKHKRKKF 727
+K + E G+K KR+K+
Sbjct: 183 LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKY 218
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,833,050
Number of Sequences: 37866
Number of extensions: 1320989
Number of successful extensions: 19507
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 311
Number of HSP's successfully gapped in prelim test: 730
Number of HSP's that attempted gapping in prelim test: 9341
Number of HSP's gapped (non-prelim): 5277
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.