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Search of human proteins with 66932988
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66932988 filamin-binding LIM protein-1 isoform c [Homo
sapiens]
(276 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens] 598 e-171
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 440 e-124
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] 269 2e-72
gi|58530845 zyxin [Homo sapiens] 212 3e-55
gi|4508047 zyxin [Homo sapiens] 212 3e-55
gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens] 192 3e-49
gi|5031887 LIM domain containing preferred translocation partner... 188 4e-48
gi|7657307 LIM domains containing 1 [Homo sapiens] 176 2e-44
gi|14249622 ajuba isoform 1 [Homo sapiens] 171 6e-43
gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens] 166 2e-41
gi|37675280 ajuba isoform 2 [Homo sapiens] 114 7e-26
gi|109638745 transforming growth factor beta 1 induced transcrip... 112 3e-25
gi|21361591 transforming growth factor beta 1 induced transcript... 112 3e-25
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 100 1e-21
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 100 2e-21
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 100 2e-21
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 100 2e-21
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 100 2e-21
gi|170932518 paxillin isoform 3 [Homo sapiens] 95 6e-20
gi|170932516 paxillin isoform 2 [Homo sapiens] 95 6e-20
gi|170932514 paxillin isoform 1 [Homo sapiens] 95 6e-20
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 94 1e-19
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 94 1e-19
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 94 1e-19
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 93 3e-19
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 93 3e-19
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 93 3e-19
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 93 3e-19
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 93 3e-19
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 93 3e-19
>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
Length = 276
Score = 598 bits (1542), Expect = e-171
Identities = 276/276 (100%), Positives = 276/276 (100%)
Query: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
Query: 61 SPWTTPGRAAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQ 120
SPWTTPGRAAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQ
Sbjct: 61 SPWTTPGRAAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQ 120
Query: 121 LAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIG 180
LAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIG
Sbjct: 121 LAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIG 180
Query: 181 DESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCED 240
DESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCED
Sbjct: 181 DESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCED 240
Query: 241 CRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC 276
CRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC
Sbjct: 241 CRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC 276
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 440 bits (1131), Expect = e-124
Identities = 202/232 (87%), Positives = 208/232 (89%), Gaps = 1/232 (0%)
Query: 46 PAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQL-FNGDICAFCHKTVSPRELAVEAMK 104
P P + P G + +P P PA P++ + DICAFCHKTVSPRELAVEAMK
Sbjct: 142 PPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMK 201
Query: 105 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA 164
RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA
Sbjct: 202 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA 261
Query: 165 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKI 224
FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKI
Sbjct: 262 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKI 321
Query: 225 ECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC 276
ECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC
Sbjct: 322 ECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC 373
Score = 171 bits (433), Expect = 6e-43
Identities = 83/83 (100%), Positives = 83/83 (100%)
Query: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
Query: 61 SPWTTPGRAAATVPAAPMQLFNG 83
SPWTTPGRAAATVPAAPMQLFNG
Sbjct: 61 SPWTTPGRAAATVPAAPMQLFNG 83
>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
Length = 374
Score = 269 bits (687), Expect = 2e-72
Identities = 127/163 (77%), Positives = 135/163 (82%), Gaps = 1/163 (0%)
Query: 46 PAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQL-FNGDICAFCHKTVSPRELAVEAMK 104
P P + P G + +P P PA P++ + DICAFCHKTVSPRELAVEAMK
Sbjct: 142 PPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMK 201
Query: 105 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA 164
RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA
Sbjct: 202 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQA 261
Query: 165 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCS 207
FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR +C+
Sbjct: 262 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCT 304
Score = 171 bits (433), Expect = 6e-43
Identities = 83/83 (100%), Positives = 83/83 (100%)
Query: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP
Sbjct: 1 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 60
Query: 61 SPWTTPGRAAATVPAAPMQLFNG 83
SPWTTPGRAAATVPAAPMQLFNG
Sbjct: 61 SPWTTPGRAAATVPAAPMQLFNG 83
Score = 41.6 bits (96), Expect = 8e-04
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 264
+C+ C + PR+ +E M R +H C+ C CR L+ Q Y + C+
Sbjct: 182 ICAFCHKTVSPRE----LAVEAMKRQYHAQCFTCRTCRRQLA----GQSFYQKDGRPLCE 233
Query: 265 PCH 267
PC+
Sbjct: 234 PCY 236
>gi|58530845 zyxin [Homo sapiens]
Length = 572
Score = 212 bits (539), Expect = 3e-55
Identities = 84/189 (44%), Positives = 124/189 (65%), Gaps = 1/189 (0%)
Query: 84 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 143
++C CH+ ++ + AV A+ + +H CFTC C +QL GQ FY +G P CE CY DTL
Sbjct: 382 ELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTL 441
Query: 144 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 203
E+C CGE + D ++RA G+A+HP CFTCV CAR + SF + N +C+ D+++++A
Sbjct: 442 EKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYA 501
Query: 204 PVCSICENPIIPRDGKD-AFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLF 262
P CS+C PI+P G+D ++ + +NFH CY+CEDC LS+E D GC+PL+ H+
Sbjct: 502 PRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVL 561
Query: 263 CKPCHVKRS 271
C+ CH R+
Sbjct: 562 CRKCHTARA 570
>gi|4508047 zyxin [Homo sapiens]
Length = 572
Score = 212 bits (539), Expect = 3e-55
Identities = 84/189 (44%), Positives = 124/189 (65%), Gaps = 1/189 (0%)
Query: 84 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 143
++C CH+ ++ + AV A+ + +H CFTC C +QL GQ FY +G P CE CY DTL
Sbjct: 382 ELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTL 441
Query: 144 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 203
E+C CGE + D ++RA G+A+HP CFTCV CAR + SF + N +C+ D+++++A
Sbjct: 442 EKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYA 501
Query: 204 PVCSICENPIIPRDGKD-AFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLF 262
P CS+C PI+P G+D ++ + +NFH CY+CEDC LS+E D GC+PL+ H+
Sbjct: 502 PRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVL 561
Query: 263 CKPCHVKRS 271
C+ CH R+
Sbjct: 562 CRKCHTARA 570
>gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]
Length = 476
Score = 192 bits (487), Expect = 3e-49
Identities = 83/186 (44%), Positives = 116/186 (62%), Gaps = 1/186 (0%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
C C + V V A+ R +H CF C TCR QL GQ FY + R CE CY TLE+
Sbjct: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEK 338
Query: 146 CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPV 205
C C + + D I+RA+G+A+HP CFTCV C R + F + + ++++C++DF+RKFAP
Sbjct: 339 CATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPR 398
Query: 206 CSICENPIIPRDG-KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 264
CS+C I+P G ++ +I + R+FH CY+CE+C +LLS E QGCYPL+ H+ CK
Sbjct: 399 CSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCK 458
Query: 265 PCHVKR 270
C R
Sbjct: 459 ACSAWR 464
>gi|5031887 LIM domain containing preferred translocation partner in
lipoma [Homo sapiens]
Length = 612
Score = 188 bits (478), Expect = 4e-48
Identities = 82/186 (44%), Positives = 118/186 (63%), Gaps = 2/186 (1%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
CA C + V AM + +H CFTC C +L GQ FY + + CEPCY +TLE+
Sbjct: 416 CARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQ 475
Query: 146 CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPV 205
C C + + + I+RA G+A+HP CFTCV C R + F + + ++C++DF++KFAP
Sbjct: 476 CNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPR 535
Query: 206 CSICENPIIPRDG-KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 264
CS+C+ PI+P G ++ +I + R+FH +CYRCEDC LLS E +QGCYPL+ H+ CK
Sbjct: 536 CSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCK 594
Query: 265 PCHVKR 270
C+ R
Sbjct: 595 TCNSAR 600
>gi|7657307 LIM domains containing 1 [Homo sapiens]
Length = 676
Score = 176 bits (446), Expect = 2e-44
Identities = 79/191 (41%), Positives = 115/191 (60%), Gaps = 7/191 (3%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-----Q 140
C C K V A +AM YH CFTC C R+L G++FY +G+ CE + Q
Sbjct: 472 CVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQ 531
Query: 141 DTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR 200
+ +RC CG ++ D I++ALG+++HP CF CV C C+ F + S+N++YC+ D+++
Sbjct: 532 QSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHK 591
Query: 201 KFAPVCSICENPIIPRDGKD-AFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNN 259
AP C+ C PI+P +G D ++ M R++H CY CEDC + L+ E + CYPL +
Sbjct: 592 VLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHR-CYPLED 650
Query: 260 HLFCKPCHVKR 270
HLFC CHVKR
Sbjct: 651 HLFCHSCHVKR 661
>gi|14249622 ajuba isoform 1 [Homo sapiens]
Length = 538
Score = 171 bits (433), Expect = 6e-43
Identities = 83/232 (35%), Positives = 129/232 (55%), Gaps = 14/232 (6%)
Query: 48 PMKTPEAGLAGRPSPWTTPG-RAAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQ 106
P +GL P P+ RA P A F C C+K + + A +A+
Sbjct: 301 PSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFG--TCIKCNKGIYGQSNACQALDSL 358
Query: 107 YHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHIIRAL 161
YH QCF C +C R L ++FY +G CE Y Q+ E+C CG ++ + I++A+
Sbjct: 359 YHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAM 418
Query: 162 GQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG-KD 220
G+++HP CF C+ C +C+ F + N+VYC+ D+++ +AP C+ C PI+P +G +D
Sbjct: 419 GKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCED 478
Query: 221 AFKIECMGRNFHENCYRCEDCRILLSVEPTDQG--CYPLNNHLFCKPCHVKR 270
++ M R++H CY CEDCR+ LS E +G C+PL+ HL C CH++R
Sbjct: 479 IVRVISMDRDYHFECYHCEDCRMQLSDE---EGCCCFPLDGHLLCHGCHMQR 527
Score = 43.5 bits (101), Expect = 2e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 86 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 137
CA C + + P E + V +M R YH +C+ C CR QL+ G + DG LC
Sbjct: 463 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 522
Query: 138 CYQDTL 143
C+ L
Sbjct: 523 CHMQRL 528
>gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
Length = 430
Score = 166 bits (420), Expect = 2e-41
Identities = 89/258 (34%), Positives = 132/258 (51%), Gaps = 26/258 (10%)
Query: 42 PWEAPAPMKTPE-AGLAGRPSPWTT--PGR------AAATVPAAPMQLFNG--------- 83
P PAP ++PE AG A P P PGR A + A +L
Sbjct: 162 PGACPAPARSPEPAGPAPFPLPALPLPPGREGGPSAAERRLEALTRELERALEARTARDY 221
Query: 84 -DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY--- 139
IC C + + A +AM YH CFTC +C R+L G++FY + C+ +
Sbjct: 222 FGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYS 281
Query: 140 --QDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDD 197
Q T ++C CG ++ + I++ALG+++HP CF C C C+ F + +N +YC+ D
Sbjct: 282 GFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRD 341
Query: 198 FYRKFAPVCSICENPIIPRDG-KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYP 256
++ FAP C+ C PI+P G + ++ M R++H CY CEDC + LS E + CYP
Sbjct: 342 YHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE-EGRRCYP 400
Query: 257 LNNHLFCKPCHVKRSAAG 274
L HL C+ CH++R G
Sbjct: 401 LAGHLLCRRCHLRRLQPG 418
>gi|37675280 ajuba isoform 2 [Homo sapiens]
Length = 121
Score = 114 bits (286), Expect = 7e-26
Identities = 46/113 (40%), Positives = 74/113 (65%), Gaps = 6/113 (5%)
Query: 161 LGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG-K 219
+G+++HP CF C+ C +C+ F + N+VYC+ D+++ +AP C+ C PI+P +G +
Sbjct: 1 MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCE 60
Query: 220 DAFKIECMGRNFHENCYRCEDCRILLSVEPTDQG--CYPLNNHLFCKPCHVKR 270
D ++ M R++H CY CEDCR+ LS E +G C+PL+ HL C CH++R
Sbjct: 61 DIVRVISMDRDYHFECYHCEDCRMQLSDE---EGCCCFPLDGHLLCHGCHMQR 110
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 17/93 (18%)
Query: 103 MKRQYHAQCFTCRTCRRQLAGQSF-------------YQKDGRPLCEPCYQDTLERCGKC 149
M + YH CF C C + L G F Y K+ P C C Q L G C
Sbjct: 1 MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEG-C 59
Query: 150 GEVVRDHIIRALGQAFHPSCFTCVTCARCIGDE 182
++VR + ++ + +H C+ C C + DE
Sbjct: 60 EDIVR---VISMDRDYHFECYHCEDCRMQLSDE 89
Score = 43.5 bits (101), Expect = 2e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 86 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLA---GQSFYQKDGRPLCEP 137
CA C + + P E + V +M R YH +C+ C CR QL+ G + DG LC
Sbjct: 46 CAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHG 105
Query: 138 CYQDTL 143
C+ L
Sbjct: 106 CHMQRL 111
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 112 bits (281), Expect = 3e-25
Identities = 55/158 (34%), Positives = 81/158 (51%), Gaps = 10/158 (6%)
Query: 85 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 144
+C C+K ++ + V A+ R +H + F C C L G SF++KDG P C CY +
Sbjct: 227 LCGSCNKPIAGQ--VVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFS 284
Query: 145 -RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 203
RCG C + +R ++ ALG +HP F CV+C GDE F + YC DF + FA
Sbjct: 285 PRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLFA 343
Query: 204 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDC 241
P C C+ PI+ I + +H +C+ C +C
Sbjct: 344 PRCQGCQGPILDN------YISALSALWHPDCFVCREC 375
Score = 83.6 bits (205), Expect = 2e-16
Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-QDTLE 144
C FC++ + R V A+ +H + F C +C + F++++GRP C + Q
Sbjct: 287 CGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 344
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
RC C + D+ I AL +HP CF C C SF + C + F+ +
Sbjct: 345 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGS 403
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLN-NHLFC 263
+C+ C P+ R + +GR FH + + C C + P +G + +C
Sbjct: 404 LCATCGLPVTGR------CVSALGRRFHPDHFTCTFC-----LRPLTKGSFQERAGKPYC 452
Query: 264 KPCHVK 269
+PC +K
Sbjct: 453 QPCFLK 458
Score = 71.6 bits (174), Expect = 7e-13
Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 100 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHII 158
+ A+ +H CF CR C +G SF++ +GRPLCE + C CG V +
Sbjct: 358 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCV 417
Query: 159 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
ALG+ FHP FTC C R + SF + YC F + F
Sbjct: 418 SALGRRFHPDHFTCTFCLRPLTKGSFQ-ERAGKPYCQPCFLKLF 460
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 112 bits (281), Expect = 3e-25
Identities = 55/158 (34%), Positives = 81/158 (51%), Gaps = 10/158 (6%)
Query: 85 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 144
+C C+K ++ + V A+ R +H + F C C L G SF++KDG P C CY +
Sbjct: 210 LCGSCNKPIAGQ--VVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFS 267
Query: 145 -RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 203
RCG C + +R ++ ALG +HP F CV+C GDE F + YC DF + FA
Sbjct: 268 PRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLFA 326
Query: 204 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDC 241
P C C+ PI+ I + +H +C+ C +C
Sbjct: 327 PRCQGCQGPILDN------YISALSALWHPDCFVCREC 358
Score = 83.6 bits (205), Expect = 2e-16
Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY-QDTLE 144
C FC++ + R V A+ +H + F C +C + F++++GRP C + Q
Sbjct: 270 CGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
RC C + D+ I AL +HP CF C C SF + C + F+ +
Sbjct: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGS 386
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLN-NHLFC 263
+C+ C P+ R + +GR FH + + C C + P +G + +C
Sbjct: 387 LCATCGLPVTGR------CVSALGRRFHPDHFTCTFC-----LRPLTKGSFQERAGKPYC 435
Query: 264 KPCHVK 269
+PC +K
Sbjct: 436 QPCFLK 441
Score = 71.6 bits (174), Expect = 7e-13
Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 100 VEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHII 158
+ A+ +H CF CR C +G SF++ +GRPLCE + C CG V +
Sbjct: 341 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCV 400
Query: 159 RALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
ALG+ FHP FTC C R + SF + YC F + F
Sbjct: 401 SALGRRFHPDHFTCTFCLRPLTKGSFQ-ERAGKPYCQPCFLKLF 443
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 100 bits (250), Expect = 1e-21
Identities = 53/182 (29%), Positives = 79/182 (43%), Gaps = 8/182 (4%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C+ C +TV P +E + +H CF C C + L +SF G C PCY++
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
RC +C + + + Q +H C C C + + F + YC+ F FAP
Sbjct: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFT-SRDEDPYCVACFGELFAP 219
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 264
CS C+ PI+ G E R++H NC+ C C S QG P + + C+
Sbjct: 220 KCSSCKRPIVGLGGGKYVSFE--DRHWHHNCFSCARC----STSLVGQGFVPDGDQVLCQ 273
Query: 265 PC 266
C
Sbjct: 274 GC 275
Score = 92.0 bits (227), Expect = 5e-19
Identities = 51/171 (29%), Positives = 78/171 (45%), Gaps = 14/171 (8%)
Query: 109 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHIIRAL---GQA 164
++ F C C L G+ + Q D P C PCY +T C +C +++ H R L +
Sbjct: 2 SESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLI-GHDSRELFYEDRH 60
Query: 165 FHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKI 224
FH CF C C R + DE F +E+ C D + F+ CS C ++P + K+
Sbjct: 61 FHEGCFRCCRCQRSLADEPFTC-QDSELLCNDCYCSAFSSQCSACGETVMP----GSRKL 115
Query: 225 ECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 275
E G+ +HE+C+ C C L + P +C PC+ + A C
Sbjct: 116 EYGGQTWHEHCFLCSGCEQPLG----SRSFVPDKGAHYCVPCYENKFAPRC 162
Score = 81.6 bits (200), Expect = 7e-16
Identities = 55/191 (28%), Positives = 78/191 (40%), Gaps = 19/191 (9%)
Query: 86 CAFCHKTVS--PRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 143
CA C + + REL E R +H CF C C+R LA + F +D LC CY
Sbjct: 40 CAECQQLIGHDSRELFYE--DRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAF 97
Query: 144 -ERCGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYR 200
+C CGE V + GQ +H CF C C + +G SF + + YC+ +
Sbjct: 98 SSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSF-VPDKGAHYCVPCYEN 156
Query: 201 KFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVE-----PTDQGCY 255
KFAP C+ C + + + +H C C C+ L+ + D C
Sbjct: 157 KFAPRCARCSKTLTQGG------VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCV 210
Query: 256 PLNNHLFCKPC 266
LF C
Sbjct: 211 ACFGELFAPKC 221
Score = 36.6 bits (83), Expect = 0.025
Identities = 14/36 (38%), Positives = 18/36 (50%)
Query: 105 RQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQ 140
R +H CF+C C L GQ F + LC+ C Q
Sbjct: 242 RHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 100 bits (248), Expect = 2e-21
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 10/201 (4%)
Query: 52 PEAGLAGRPSPWTTPGRAAATVPAAPMQLFNG--DICAFCHKTVSPRELAVEAMKRQYHA 109
P G A P+ P A TV A + +C C+ + R + AM R +H
Sbjct: 405 PRGGPAYTPAGPQVPPLARGTVQRAERFPASSRTPLCGHCNNVI--RGPFLVAMGRSWHP 462
Query: 110 QCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRALGQAFHPS 168
+ FTC C+ LA F ++ CE CY+ C KC + ++ AL Q +H +
Sbjct: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTT 522
Query: 169 CFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMG 228
CF C C + G+ F + E YC D+ F+ C C+ P+ + D F IE +G
Sbjct: 523 CFVCAACKKPFGNSLFHM-EDGEPYCEKDYINLFSTKCHGCDFPV---EAGDKF-IEALG 577
Query: 229 RNFHENCYRCEDCRILLSVEP 249
+H+ C+ C C + L +P
Sbjct: 578 HTWHDTCFICAVCHVNLEGQP 598
Score = 71.6 bits (174), Expect = 7e-13
Identities = 64/250 (25%), Positives = 101/250 (40%), Gaps = 38/250 (15%)
Query: 45 APAPMKTPEAGLAGRPSPWTT--PGRAAATVPA-------APMQLFNGDICAFCHKTVSP 95
+PAP TP A PSP T P A A P+ AP ++G P
Sbjct: 322 SPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSG---GPAEPASRP 378
Query: 96 RELAVEAMKRQYHAQCFTCRTCRRQL-AGQSFYQKDGRPLCEPCYQDTLER--------- 145
+ ++ +++ T ++ L G Y G P P + T++R
Sbjct: 379 PWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAG-PQVPPLARGTVQRAERFPASSR 437
Query: 146 ---CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
CG C V+R + A+G+++HP FTC C + D F + QN VYC + + F
Sbjct: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCF-VEEQNNVYCERCYEQFF 496
Query: 203 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCR-----ILLSVEPTDQGCYPL 257
AP+C+ C I+ + + + +H C+ C C+ L +E + C
Sbjct: 497 APLCAKCNTKIMGE------VMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD 550
Query: 258 NNHLFCKPCH 267
+LF CH
Sbjct: 551 YINLFSTKCH 560
Score = 46.2 bits (108), Expect = 3e-05
Identities = 20/51 (39%), Positives = 25/51 (49%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 136
C C V + +EA+ +H CF C C L GQ FY K RPLC+
Sbjct: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 100 bits (248), Expect = 2e-21
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 10/201 (4%)
Query: 52 PEAGLAGRPSPWTTPGRAAATVPAAPMQLFNG--DICAFCHKTVSPRELAVEAMKRQYHA 109
P G A P+ P A TV A + +C C+ + R + AM R +H
Sbjct: 515 PRGGPAYTPAGPQVPPLARGTVQRAERFPASSRTPLCGHCNNVI--RGPFLVAMGRSWHP 572
Query: 110 QCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRALGQAFHPS 168
+ FTC C+ LA F ++ CE CY+ C KC + ++ AL Q +H +
Sbjct: 573 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTT 632
Query: 169 CFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMG 228
CF C C + G+ F + E YC D+ F+ C C+ P+ + D F IE +G
Sbjct: 633 CFVCAACKKPFGNSLFHM-EDGEPYCEKDYINLFSTKCHGCDFPV---EAGDKF-IEALG 687
Query: 229 RNFHENCYRCEDCRILLSVEP 249
+H+ C+ C C + L +P
Sbjct: 688 HTWHDTCFICAVCHVNLEGQP 708
Score = 71.6 bits (174), Expect = 7e-13
Identities = 64/250 (25%), Positives = 101/250 (40%), Gaps = 38/250 (15%)
Query: 45 APAPMKTPEAGLAGRPSPWTT--PGRAAATVPA-------APMQLFNGDICAFCHKTVSP 95
+PAP TP A PSP T P A A P+ AP ++G P
Sbjct: 432 SPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSG---GPAEPASRP 488
Query: 96 RELAVEAMKRQYHAQCFTCRTCRRQL-AGQSFYQKDGRPLCEPCYQDTLER--------- 145
+ ++ +++ T ++ L G Y G P P + T++R
Sbjct: 489 PWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAG-PQVPPLARGTVQRAERFPASSR 547
Query: 146 ---CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
CG C V+R + A+G+++HP FTC C + D F + QN VYC + + F
Sbjct: 548 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCF-VEEQNNVYCERCYEQFF 606
Query: 203 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCR-----ILLSVEPTDQGCYPL 257
AP+C+ C I+ + + + +H C+ C C+ L +E + C
Sbjct: 607 APLCAKCNTKIMGE------VMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKD 660
Query: 258 NNHLFCKPCH 267
+LF CH
Sbjct: 661 YINLFSTKCH 670
Score = 46.2 bits (108), Expect = 3e-05
Identities = 20/51 (39%), Positives = 25/51 (49%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 136
C C V + +EA+ +H CF C C L GQ FY K RPLC+
Sbjct: 669 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 100 bits (248), Expect = 2e-21
Identities = 58/184 (31%), Positives = 89/184 (48%), Gaps = 12/184 (6%)
Query: 59 RPSPWTTPGRAAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCR 118
+PS T + A +PA +CA C++ + R + A+ + +H + F C C+
Sbjct: 288 QPSDQDTLVQRAEHIPAGKRT----PMCAHCNQVI--RGPFLVALGKSWHPEEFNCAHCK 341
Query: 119 RQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 177
+A F ++ G CE CY+ CG+C + +I AL Q +H SCF CV C +
Sbjct: 342 NTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGK 401
Query: 178 CIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYR 237
I + F L E YC D+Y F +C CE PI + D F +E +G +H+ C+
Sbjct: 402 PIRNNVFHL-EDGEPYCETDYYALFGTICHGCEFPI---EAGDMF-LEALGYTWHDTCFV 456
Query: 238 CEDC 241
C C
Sbjct: 457 CSVC 460
Score = 58.5 bits (140), Expect = 6e-09
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
C C + + + A+K+ +H CF C C + + F+ +DG P CE Y
Sbjct: 370 CGRCQRKILGE--VISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
Query: 146 -CGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESF 184
C C + D + ALG +H +CF C C + ++F
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTF 469
Score = 48.1 bits (113), Expect = 8e-06
Identities = 19/54 (35%), Positives = 29/54 (53%)
Query: 83 GDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 136
G IC C + ++ +EA+ +H CF C C L GQ+F+ K +PLC+
Sbjct: 426 GTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 100 bits (248), Expect = 2e-21
Identities = 58/184 (31%), Positives = 89/184 (48%), Gaps = 12/184 (6%)
Query: 59 RPSPWTTPGRAAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCR 118
+PS T + A +PA +CA C++ + R + A+ + +H + F C C+
Sbjct: 397 QPSDQDTLVQRAEHIPAGKRT----PMCAHCNQVI--RGPFLVALGKSWHPEEFNCAHCK 450
Query: 119 RQLAGQSFYQKDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR 177
+A F ++ G CE CY+ CG+C + +I AL Q +H SCF CV C +
Sbjct: 451 NTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGK 510
Query: 178 CIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYR 237
I + F L E YC D+Y F +C CE PI + D F +E +G +H+ C+
Sbjct: 511 PIRNNVFHL-EDGEPYCETDYYALFGTICHGCEFPI---EAGDMF-LEALGYTWHDTCFV 565
Query: 238 CEDC 241
C C
Sbjct: 566 CSVC 569
Score = 58.5 bits (140), Expect = 6e-09
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
C C + + + A+K+ +H CF C C + + F+ +DG P CE Y
Sbjct: 479 CGRCQRKILGE--VISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 536
Query: 146 -CGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESF 184
C C + D + ALG +H +CF C C + ++F
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTF 578
Score = 48.1 bits (113), Expect = 8e-06
Identities = 19/54 (35%), Positives = 29/54 (53%)
Query: 83 GDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 136
G IC C + ++ +EA+ +H CF C C L GQ+F+ K +PLC+
Sbjct: 535 GTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 95.1 bits (235), Expect = 6e-20
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 10/158 (6%)
Query: 85 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 144
+C C K ++ + V AM + +H + F C C+ ++ ++F+++DG+P CE Y +
Sbjct: 190 VCGACKKPIAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFS 247
Query: 145 -RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 203
RC C + D ++ AL + +HP F C C G E F + YC D++ FA
Sbjct: 248 PRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFA 306
Query: 204 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDC 241
P C C I+ I + +H C+ C +C
Sbjct: 307 PKCGGCARAILEN------YISALNTLWHPECFVCREC 338
Score = 82.0 bits (201), Expect = 5e-16
Identities = 49/186 (26%), Positives = 83/186 (44%), Gaps = 16/186 (8%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 144
C +C+ + + V A+ R +H + F C C + F++KDG+ C Y D
Sbjct: 250 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 307
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
+CG C + ++ I AL +HP CF C C + SF + YC ++ +
Sbjct: 308 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 366
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCY-PLNNHLFC 263
+CS C+ PI R I M + FH + C C ++ ++G + N+ +C
Sbjct: 367 LCSGCQKPITGR------CITAMAKKFHPEHFVCAFC-----LKQLNKGTFKEQNDKPYC 415
Query: 264 KPCHVK 269
+ C +K
Sbjct: 416 QNCFLK 421
Score = 65.5 bits (158), Expect = 5e-11
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C + + E + A+ +H +CF CR C SF++ DG+P CE Y +
Sbjct: 309 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
C C + + I A+ + FHP F C C + + +F ++ YC + F + F
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLKLF 423
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 95.1 bits (235), Expect = 6e-20
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 10/158 (6%)
Query: 85 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 144
+C C K ++ + V AM + +H + F C C+ ++ ++F+++DG+P CE Y +
Sbjct: 323 VCGACKKPIAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFS 380
Query: 145 -RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 203
RC C + D ++ AL + +HP F C C G E F + YC D++ FA
Sbjct: 381 PRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFA 439
Query: 204 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDC 241
P C C I+ I + +H C+ C +C
Sbjct: 440 PKCGGCARAILEN------YISALNTLWHPECFVCREC 471
Score = 82.0 bits (201), Expect = 5e-16
Identities = 49/186 (26%), Positives = 83/186 (44%), Gaps = 16/186 (8%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 144
C +C+ + + V A+ R +H + F C C + F++KDG+ C Y D
Sbjct: 383 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 440
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
+CG C + ++ I AL +HP CF C C + SF + YC ++ +
Sbjct: 441 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 499
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCY-PLNNHLFC 263
+CS C+ PI R I M + FH + C C ++ ++G + N+ +C
Sbjct: 500 LCSGCQKPITGR------CITAMAKKFHPEHFVCAFC-----LKQLNKGTFKEQNDKPYC 548
Query: 264 KPCHVK 269
+ C +K
Sbjct: 549 QNCFLK 554
Score = 65.5 bits (158), Expect = 5e-11
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C + + E + A+ +H +CF CR C SF++ DG+P CE Y +
Sbjct: 442 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
C C + + I A+ + FHP F C C + + +F ++ YC + F + F
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLKLF 556
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 95.1 bits (235), Expect = 6e-20
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 10/158 (6%)
Query: 85 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE 144
+C C K ++ + V AM + +H + F C C+ ++ ++F+++DG+P CE Y +
Sbjct: 357 VCGACKKPIAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFS 414
Query: 145 -RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 203
RC C + D ++ AL + +HP F C C G E F + YC D++ FA
Sbjct: 415 PRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFA 473
Query: 204 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDC 241
P C C I+ I + +H C+ C +C
Sbjct: 474 PKCGGCARAILEN------YISALNTLWHPECFVCREC 505
Score = 82.0 bits (201), Expect = 5e-16
Identities = 49/186 (26%), Positives = 83/186 (44%), Gaps = 16/186 (8%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLE- 144
C +C+ + + V A+ R +H + F C C + F++KDG+ C Y D
Sbjct: 417 CYYCNGPILDK--VVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP 474
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
+CG C + ++ I AL +HP CF C C + SF + YC ++ +
Sbjct: 475 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSF-FEHDGQPYCEVHYHERRGS 533
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCY-PLNNHLFC 263
+CS C+ PI R I M + FH + C C ++ ++G + N+ +C
Sbjct: 534 LCSGCQKPITGR------CITAMAKKFHPEHFVCAFC-----LKQLNKGTFKEQNDKPYC 582
Query: 264 KPCHVK 269
+ C +K
Sbjct: 583 QNCFLK 588
Score = 65.5 bits (158), Expect = 5e-11
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C + + E + A+ +H +CF CR C SF++ DG+P CE Y +
Sbjct: 476 CGGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
C C + + I A+ + FHP F C C + + +F ++ YC + F + F
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFK-EQNDKPYCQNCFLKLF 590
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 94.4 bits (233), Expect = 1e-19
Identities = 55/178 (30%), Positives = 81/178 (45%), Gaps = 8/178 (4%)
Query: 69 AAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQ 128
AA VP +C CHK + R L A+ YH + F C C + L F++
Sbjct: 231 AAGGVPGGGSNNGKTPVCHQCHKVIRGRYLV--ALGHAYHPEEFVCSQCGKVLEEGGFFE 288
Query: 129 KDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALG 187
+ G C PCY C KC + + I+ AL +H CFTC C I + +F +
Sbjct: 289 EKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYM- 347
Query: 188 SQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILL 245
+ YC D+ + F C C+ I D D F +E +G ++H+ C+ C C+I L
Sbjct: 348 EEGVPYCERDYEKMFGTKCHGCDFKI---DAGDRF-LEALGFSWHDTCFVCAICQINL 401
Score = 44.7 bits (104), Expect = 9e-05
Identities = 19/54 (35%), Positives = 28/54 (51%)
Query: 83 GDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 136
G C C + + +EA+ +H CF C C+ L G++FY K RPLC+
Sbjct: 363 GTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 416
Score = 30.8 bits (68), Expect = 1.3
Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 10/72 (13%)
Query: 204 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 263
PVC C I R + +G +H + C C +L + G + +FC
Sbjct: 246 PVCHQCHKVIRGR------YLVALGHAYHPEEFVCSQCGKVLE----EGGFFEEKGAIFC 295
Query: 264 KPCHVKRSAAGC 275
PC+ R A C
Sbjct: 296 PPCYDVRYAPSC 307
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 94.4 bits (233), Expect = 1e-19
Identities = 55/178 (30%), Positives = 81/178 (45%), Gaps = 8/178 (4%)
Query: 69 AAATVPAAPMQLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQ 128
AA VP +C CHK + R L A+ YH + F C C + L F++
Sbjct: 265 AAGGVPGGGSNNGKTPVCHQCHKVIRGRYLV--ALGHAYHPEEFVCSQCGKVLEEGGFFE 322
Query: 129 KDGRPLCEPCYQDTLE-RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALG 187
+ G C PCY C KC + + I+ AL +H CFTC C I + +F +
Sbjct: 323 EKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYM- 381
Query: 188 SQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILL 245
+ YC D+ + F C C+ I D D F +E +G ++H+ C+ C C+I L
Sbjct: 382 EEGVPYCERDYEKMFGTKCHGCDFKI---DAGDRF-LEALGFSWHDTCFVCAICQINL 435
Score = 44.7 bits (104), Expect = 9e-05
Identities = 19/54 (35%), Positives = 28/54 (51%)
Query: 83 GDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 136
G C C + + +EA+ +H CF C C+ L G++FY K RPLC+
Sbjct: 397 GTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
Score = 30.8 bits (68), Expect = 1.3
Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 10/72 (13%)
Query: 204 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 263
PVC C I R + +G +H + C C +L + G + +FC
Sbjct: 280 PVCHQCHKVIRGR------YLVALGHAYHPEEFVCSQCGKVLE----EGGFFEEKGAIFC 329
Query: 264 KPCHVKRSAAGC 275
PC+ R A C
Sbjct: 330 PPCYDVRYAPSC 341
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 94.0 bits (232), Expect = 1e-19
Identities = 66/237 (27%), Positives = 93/237 (39%), Gaps = 34/237 (14%)
Query: 56 LAGRPSPWTTPGRAAATVPAAPMQLFN------GDICAFCHKTVSPRELAVEAMKRQYHA 109
+ GR W G + PAA ++ N +C C SP E V + YH
Sbjct: 1 MTGRKRKWGETGTGSGAAPAAALRWSNMSDALANAVCQRCQARFSPAERIVNSNGELYHE 60
Query: 110 QCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRALGQAFHPS 168
CF C C R FY+ +GR CE +Q CG CGE + +I+A+ +HP
Sbjct: 61 HCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPG 120
Query: 169 CFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP-----VCSIC-----ENPIIPRDG 218
CF C C + D F + + C R+ A +C C E P++ R
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHL-CRPCHNREKAKGLGKYICQRCHLVIDEQPLMFR-- 177
Query: 219 KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 275
DA +H + + C C L+ E + L L+C PCH K C
Sbjct: 178 SDA---------YHPDHFNCTHCGKELTAEARE-----LKGELYCLPCHDKMGVPIC 220
Score = 65.1 bits (157), Expect = 6e-11
Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Query: 85 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL- 143
IC C + + R V A+ +Q+H + F C C + G Y+K G CE Y
Sbjct: 219 ICGACRRPIEGR--VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 276
Query: 144 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTC 175
+ C C V+ ++ AL +A+ SCF+C TC
Sbjct: 277 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 308
Score = 60.8 bits (146), Expect = 1e-09
Identities = 38/166 (22%), Positives = 69/166 (41%), Gaps = 13/166 (7%)
Query: 85 ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDT-L 143
IC CH + + L + YH F C C ++L ++ K G C PC+ +
Sbjct: 161 ICQRCHLVIDEQPLMFRS--DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGV 217
Query: 144 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCAR-CIGDESFALGSQNEVYCLDDFYRKF 202
CG C + ++ ALG+ +H F C C + +G + + YC + + F
Sbjct: 218 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYE--KKGLAYCETHYNQLF 275
Query: 203 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVE 248
VC C + I + + + + + +C+ C C L+++
Sbjct: 276 GDVCYNCSHVI------EGDVVSALNKAWCVSCFSCSTCNSKLTLK 315
Score = 41.6 bits (96), Expect = 8e-04
Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Query: 79 QLFNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQS-FYQKDGRPLCEP 137
QLF GD+C C + V A+ + + CF+C TC +L ++ F + D +P+C+
Sbjct: 273 QLF-GDVCYNCSHVIEGD--VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKR 329
Query: 138 CYQ 140
CY+
Sbjct: 330 CYE 332
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 92.8 bits (229), Expect = 3e-19
Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
C C K + + VE +H CFTC C++ + SF+ K C C++ +
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160
Query: 146 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
C KC + + I Q +H CF CVTC++ + + F +++ YC+D + A
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 219
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 246
C+ C+NPI GK + + G+++H+ C+ C+ C + L+
Sbjct: 220 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 260
Score = 82.8 bits (203), Expect = 3e-16
Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 17/201 (8%)
Query: 81 FNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-Y 139
F + C C K + V R +H CF C C LA ++F KD + LC C
Sbjct: 35 FCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTT 94
Query: 140 QDTLERCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDD 197
++ +C C + V D + G +H CFTC C + IG SF + YC+
Sbjct: 95 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTC 153
Query: 198 FYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPL 257
KFA C C N I G I + +H +C+ C C S + Q +
Sbjct: 154 HETKFAKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAV 203
Query: 258 NNHLFCKPCH---VKRSAAGC 275
+ +C C+ V + AGC
Sbjct: 204 EDQYYCVDCYKNFVAKKCAGC 224
Score = 75.1 bits (183), Expect = 6e-14
Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)
Query: 109 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 165
A+ F C CR L G+ + QKDG C C+ C +C + + + + +
Sbjct: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 61
Query: 166 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 225
H +CF C C + +E+F + N++ C R+ +P C C I+ D +E
Sbjct: 62 HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 116
Query: 226 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 275
G +H++C+ C +C+ ++ +P +C CH + A C
Sbjct: 117 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 162
Score = 64.3 bits (155), Expect = 1e-10
Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C+K ++ + + + +HA CF C TC ++LAGQ F + + C CY++ + +
Sbjct: 162 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
Query: 145 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 196
+C C + ++ GQ++H CF C C+ + ++ F Q +VYC D
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 275
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 92.8 bits (229), Expect = 3e-19
Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
C C K + + VE +H CFTC C++ + SF+ K C C++ +
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160
Query: 146 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
C KC + + I Q +H CF CVTC++ + + F +++ YC+D + A
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 219
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 246
C+ C+NPI GK + + G+++H+ C+ C+ C + L+
Sbjct: 220 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 260
Score = 82.8 bits (203), Expect = 3e-16
Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 17/201 (8%)
Query: 81 FNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-Y 139
F + C C K + V R +H CF C C LA ++F KD + LC C
Sbjct: 35 FCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTT 94
Query: 140 QDTLERCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDD 197
++ +C C + V D + G +H CFTC C + IG SF + YC+
Sbjct: 95 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTC 153
Query: 198 FYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPL 257
KFA C C N I G I + +H +C+ C C S + Q +
Sbjct: 154 HETKFAKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAV 203
Query: 258 NNHLFCKPCH---VKRSAAGC 275
+ +C C+ V + AGC
Sbjct: 204 EDQYYCVDCYKNFVAKKCAGC 224
Score = 75.1 bits (183), Expect = 6e-14
Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)
Query: 109 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 165
A+ F C CR L G+ + QKDG C C+ C +C + + + + +
Sbjct: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 61
Query: 166 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 225
H +CF C C + +E+F + N++ C R+ +P C C I+ D +E
Sbjct: 62 HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 116
Query: 226 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 275
G +H++C+ C +C+ ++ +P +C CH + A C
Sbjct: 117 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 162
Score = 64.3 bits (155), Expect = 1e-10
Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C+K ++ + + + +HA CF C TC ++LAGQ F + + C CY++ + +
Sbjct: 162 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
Query: 145 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 196
+C C + ++ GQ++H CF C C+ + ++ F Q +VYC D
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 275
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 92.8 bits (229), Expect = 3e-19
Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
C C K + + VE +H CFTC C++ + SF+ K C C++ +
Sbjct: 130 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 189
Query: 146 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
C KC + + I Q +H CF CVTC++ + + F +++ YC+D + A
Sbjct: 190 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 248
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 246
C+ C+NPI GK + + G+++H+ C+ C+ C + L+
Sbjct: 249 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 289
Score = 82.8 bits (203), Expect = 3e-16
Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 17/201 (8%)
Query: 81 FNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-Y 139
F + C C K + V R +H CF C C LA ++F KD + LC C
Sbjct: 64 FCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTT 123
Query: 140 QDTLERCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDD 197
++ +C C + V D + G +H CFTC C + IG SF + YC+
Sbjct: 124 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTC 182
Query: 198 FYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPL 257
KFA C C N I G I + +H +C+ C C S + Q +
Sbjct: 183 HETKFAKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAV 232
Query: 258 NNHLFCKPCH---VKRSAAGC 275
+ +C C+ V + AGC
Sbjct: 233 EDQYYCVDCYKNFVAKKCAGC 253
Score = 75.1 bits (183), Expect = 6e-14
Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)
Query: 109 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 165
A+ F C CR L G+ + QKDG C C+ C +C + + + + +
Sbjct: 31 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 90
Query: 166 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 225
H +CF C C + +E+F + N++ C R+ +P C C I+ D +E
Sbjct: 91 HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 145
Query: 226 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 275
G +H++C+ C +C+ ++ +P +C CH + A C
Sbjct: 146 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 191
Score = 64.3 bits (155), Expect = 1e-10
Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C+K ++ + + + +HA CF C TC ++LAGQ F + + C CY++ + +
Sbjct: 191 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 248
Query: 145 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 196
+C C + ++ GQ++H CF C C+ + ++ F Q +VYC D
Sbjct: 249 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 304
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 92.8 bits (229), Expect = 3e-19
Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
C C K + + VE +H CFTC C++ + SF+ K C C++ +
Sbjct: 117 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 176
Query: 146 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
C KC + + I Q +H CF CVTC++ + + F +++ YC+D + A
Sbjct: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 235
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 246
C+ C+NPI GK + + G+++H+ C+ C+ C + L+
Sbjct: 236 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 276
Score = 82.8 bits (203), Expect = 3e-16
Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 17/201 (8%)
Query: 81 FNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-Y 139
F + C C K + V R +H CF C C LA ++F KD + LC C
Sbjct: 51 FCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTT 110
Query: 140 QDTLERCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDD 197
++ +C C + V D + G +H CFTC C + IG SF + YC+
Sbjct: 111 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTC 169
Query: 198 FYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPL 257
KFA C C N I G I + +H +C+ C C S + Q +
Sbjct: 170 HETKFAKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAV 219
Query: 258 NNHLFCKPCH---VKRSAAGC 275
+ +C C+ V + AGC
Sbjct: 220 EDQYYCVDCYKNFVAKKCAGC 240
Score = 75.5 bits (184), Expect = 5e-14
Identities = 46/189 (24%), Positives = 79/189 (41%), Gaps = 17/189 (8%)
Query: 90 HKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGK 148
H+ P V M A+ F C CR L G+ + QKDG C C+ C +
Sbjct: 4 HRHSGPSSYKVGTM-----AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVE 58
Query: 149 CGEVV--RDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVC 206
C + + + + +H +CF C C + +E+F + N++ C R+ +P C
Sbjct: 59 CRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKC 117
Query: 207 SICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPC 266
C I+ D +E G +H++C+ C +C+ ++ +P +C C
Sbjct: 118 KGCFKAIVAGDQ----NVEYKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTC 169
Query: 267 HVKRSAAGC 275
H + A C
Sbjct: 170 HETKFAKHC 178
Score = 64.3 bits (155), Expect = 1e-10
Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C+K ++ + + + +HA CF C TC ++LAGQ F + + C CY++ + +
Sbjct: 178 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
Query: 145 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 196
+C C + ++ GQ++H CF C C+ + ++ F Q +VYC D
Sbjct: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 291
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 92.8 bits (229), Expect = 3e-19
Identities = 46/162 (28%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145
C C K + + VE +H CFTC C++ + SF+ K C C++ +
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160
Query: 146 -CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
C KC + + I Q +H CF CVTC++ + + F +++ YC+D + A
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFT-AVEDQYYCVDCYKNFVAK 219
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLS 246
C+ C+NPI GK + + G+++H+ C+ C+ C + L+
Sbjct: 220 KCAGCKNPITGF-GKGSSVVAYEGQSWHDYCFHCKKCSVNLA 260
Score = 82.8 bits (203), Expect = 3e-16
Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 17/201 (8%)
Query: 81 FNGDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPC-Y 139
F + C C K + V R +H CF C C LA ++F KD + LC C
Sbjct: 35 FCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTT 94
Query: 140 QDTLERCGKCGE--VVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDD 197
++ +C C + V D + G +H CFTC C + IG SF + YC+
Sbjct: 95 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSF-FPKGEDFYCVTC 153
Query: 198 FYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPL 257
KFA C C N I G I + +H +C+ C C S + Q +
Sbjct: 154 HETKFAKHCVKC-NKAITSGG-----ITYQDQPWHADCFVCVTC----SKKLAGQRFTAV 203
Query: 258 NNHLFCKPCH---VKRSAAGC 275
+ +C C+ V + AGC
Sbjct: 204 EDQYYCVDCYKNFVAKKCAGC 224
Score = 75.1 bits (183), Expect = 6e-14
Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 12/170 (7%)
Query: 109 AQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD-TLERCGKCGEVV--RDHIIRALGQAF 165
A+ F C CR L G+ + QKDG C C+ C +C + + + + +
Sbjct: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFW 61
Query: 166 HPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIE 225
H +CF C C + +E+F + N++ C R+ +P C C I+ D +E
Sbjct: 62 HDTCFRCAKCLHPLANETF-VAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQ----NVE 116
Query: 226 CMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 275
G +H++C+ C +C+ ++ +P +C CH + A C
Sbjct: 117 YKGTVWHKDCFTCSNCKQVIGT----GSFFPKGEDFYCVTCHETKFAKHC 162
Score = 64.3 bits (155), Expect = 1e-10
Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 9/117 (7%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C+K ++ + + + +HA CF C TC ++LAGQ F + + C CY++ + +
Sbjct: 162 CVKCNKAITSGGITYQ--DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
Query: 145 RCGKCGEVVR-----DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLD 196
+C C + ++ GQ++H CF C C+ + ++ F Q +VYC D
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-HQEQVYCPD 275
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 92.8 bits (229), Expect = 3e-19
Identities = 49/182 (26%), Positives = 79/182 (43%), Gaps = 8/182 (4%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQ-DTLE 144
C C KT+ P +E +H CF C C++ + +SF KD + C PCY+
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
Query: 145 RCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAP 204
+C +C + + + Q +H CF C C + + + F + YCL+ F +A
Sbjct: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFT-ARDDFAYCLNCFCDLYAK 219
Query: 205 VCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 264
C+ C NPI G E R +H +C+ C+ C + L +G + + C
Sbjct: 220 KCAGCTNPISGLGGTKYISFE--ERQWHNDCFNCKKCSLSL----VGRGFLTERDDILCP 273
Query: 265 PC 266
C
Sbjct: 274 DC 275
Score = 80.5 bits (197), Expect = 1e-15
Identities = 46/169 (27%), Positives = 80/169 (47%), Gaps = 16/169 (9%)
Query: 112 FTCRTCRRQLAGQSFYQKDGRPLCEPCYQ----DTLERCGK-CGEVVRDHIIRALGQAFH 166
F C C L G+ + ++ P C C++ +T E CGK G +D + + +H
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKD--LSYKDRHWH 62
Query: 167 PSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIEC 226
+CF C C + D+ FA ++++ C D + +++ C C+ I+P K+E
Sbjct: 63 EACFHCSQCRNSLVDKPFA-AKEDQLLCTDCYSNEYSSKCQECKKTIMP----GTRKMEY 117
Query: 227 MGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGC 275
G ++HE C+ C C+ + + P +N FC PC+ K+ A C
Sbjct: 118 KGSSWHETCFICHRCQQPIGT----KSFIPKDNQNFCVPCYEKQHAMQC 162
Score = 76.3 bits (186), Expect = 3e-14
Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 21/198 (10%)
Query: 86 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL-E 144
C C K + + R +H CF C CR L + F K+ + LC CY +
Sbjct: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
Query: 145 RCGKCGEVVR--DHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKF 202
+C +C + + + G ++H +CF C C + IG +SF + N+ +C+ + ++
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSF-IPKDNQNFCVPCYEKQH 158
Query: 203 APVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVE---PTDQGCYPLN- 258
A C C+ PI + + +H+ C+ C CR LS + D Y LN
Sbjct: 159 AMQCVQCKKPITTGG------VTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNC 212
Query: 259 -NHLFCKPCHVKRSAAGC 275
L+ K C AGC
Sbjct: 213 FCDLYAKKC------AGC 224
Score = 36.6 bits (83), Expect = 0.025
Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 86 CAFCHKTVS----PRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQD 141
CA C +S + ++ E +RQ+H CF C+ C L G+ F + LC C +D
Sbjct: 221 CAGCTNPISGLGGTKYISFE--ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.138 0.470
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,613,024
Number of Sequences: 37866
Number of extensions: 679946
Number of successful extensions: 5048
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 116
Number of HSP's that attempted gapping in prelim test: 3984
Number of HSP's gapped (non-prelim): 639
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.