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Search of human proteins with 66730421
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66730421 ATPase type 13A5 [Homo sapiens]
(1218 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66730421 ATPase type 13A5 [Homo sapiens] 2465 0.0
gi|66932949 ATPase type 13A4 [Homo sapiens] 1407 0.0
gi|148839292 ATPase type 13A3 [Homo sapiens] 905 0.0
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 764 0.0
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 763 0.0
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens] 712 0.0
gi|170016077 ATPase type 13A1 [Homo sapiens] 267 5e-71
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 129 1e-29
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 123 1e-27
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 115 3e-25
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 115 3e-25
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 115 3e-25
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 114 4e-25
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 114 4e-25
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 114 4e-25
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 114 4e-25
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 113 1e-24
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 113 1e-24
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 111 5e-24
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 111 5e-24
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 109 2e-23
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 108 2e-23
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 101 5e-21
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 91 5e-18
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 91 5e-18
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 91 5e-18
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 91 5e-18
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 91 5e-18
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 91 5e-18
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 91 5e-18
>gi|66730421 ATPase type 13A5 [Homo sapiens]
Length = 1218
Score = 2465 bits (6389), Expect = 0.0
Identities = 1218/1218 (100%), Positives = 1218/1218 (100%)
Query: 1 MEENSKKDHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVW 60
MEENSKKDHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVW
Sbjct: 1 MEENSKKDHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVW 60
Query: 61 ANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWEESLVADRHSVINQ 120
ANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWEESLVADRHSVINQ
Sbjct: 61 ANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWEESLVADRHSVINQ 120
Query: 121 ALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRR 180
ALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRR
Sbjct: 121 ALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRR 180
Query: 181 LVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVL 240
LVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVL
Sbjct: 181 LVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVL 240
Query: 241 SVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAV 300
SVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAV
Sbjct: 241 SVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAV 300
Query: 301 LIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSG 360
LIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSG
Sbjct: 301 LIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSG 360
Query: 361 QGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVY 420
QGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVY
Sbjct: 361 QGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVY 420
Query: 421 MYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQI 480
MYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQI
Sbjct: 421 MYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQI 480
Query: 481 NLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLN 540
NLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLN
Sbjct: 481 NLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLN 540
Query: 541 GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPF 600
GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPF
Sbjct: 541 GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPF 600
Query: 601 SSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIAL 660
SSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIAL
Sbjct: 601 SSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIAL 660
Query: 661 AHKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITG 720
AHKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITG
Sbjct: 661 AHKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITG 720
Query: 721 DNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTG 780
DNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTG
Sbjct: 721 DNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTG 780
Query: 781 NSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQK 840
NSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQK
Sbjct: 781 NSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQK 840
Query: 841 LNYYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALV 900
LNYYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALV
Sbjct: 841 LNYYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALV 900
Query: 901 SSFGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLA 960
SSFGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLA
Sbjct: 901 SSFGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLA 960
Query: 961 PYRPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFST 1020
PYRPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFST
Sbjct: 961 PYRPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFST 1020
Query: 1021 NVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSF 1080
NVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSF
Sbjct: 1021 NVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSF 1080
Query: 1081 LLLAALGLTIFILFSDFQVIYRGMELIPTITSWRVLILVVALTQFCVAFFVEDSILQNHE 1140
LLLAALGLTIFILFSDFQVIYRGMELIPTITSWRVLILVVALTQFCVAFFVEDSILQNHE
Sbjct: 1081 LLLAALGLTIFILFSDFQVIYRGMELIPTITSWRVLILVVALTQFCVAFFVEDSILQNHE 1140
Query: 1141 LWLLIKREFGFYSKSQYRTWQKKLAEDSTWPPINRTDYSGDGKNGFYINGGYESHEQIPK 1200
LWLLIKREFGFYSKSQYRTWQKKLAEDSTWPPINRTDYSGDGKNGFYINGGYESHEQIPK
Sbjct: 1141 LWLLIKREFGFYSKSQYRTWQKKLAEDSTWPPINRTDYSGDGKNGFYINGGYESHEQIPK 1200
Query: 1201 RKLKLGGQPTEQHFWARL 1218
RKLKLGGQPTEQHFWARL
Sbjct: 1201 RKLKLGGQPTEQHFWARL 1218
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 1407 bits (3642), Expect = 0.0
Identities = 709/1200 (59%), Positives = 900/1200 (75%), Gaps = 18/1200 (1%)
Query: 6 KKDHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVWANCIP 65
+K ALLN+GEE+E+E+FGYR RK+ CL S+ + G L LVFYWRP W VWA+C+P
Sbjct: 5 EKGQHALLNEGEENEMEIFGYRTQGCRKSLCLAGSIFSFGILPLVFYWRPAWHVWAHCVP 64
Query: 66 CPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWEESLVADRHSVINQALIKP 125
C LQEADTVLLRTTDEFQ Y KKV +YLS L + L+ D +IN+A+ KP
Sbjct: 65 CSLQEADTVLLRTTDEFQIYSWKKVIWIYLSALNSAFGLTPDHPLMTDEEYIINRAIRKP 124
Query: 126 ELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGP 185
+LK+RC++VQKIRYVWN LE +FQK+G LED S + IHQ FG GLT EEQE+RRL+CGP
Sbjct: 125 DLKVRCIKVQKIRYVWNYLEGQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGP 184
Query: 186 NAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDL 245
N I+VE+ PIWKLL+K+VLNPFY+FQ F++ LW S+ Y EY+ AIII+++ISI L+VYDL
Sbjct: 185 NTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDL 244
Query: 246 RQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPG-KFSLPCDAVLIDG 304
R+QSVKLH+LVE HN + V++ + G++ELESR+LVPGD+LIL G K +PCDAVLI+G
Sbjct: 245 REQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDAVLIEG 304
Query: 305 SCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPV 364
SCVV+EGMLTGESIPVTKTPLP+M++++PWK S DY++HVLFCGTEVIQ K + G V
Sbjct: 305 SCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTV 364
Query: 365 RAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHG 424
RAVVLQTG+NTAKGDLVRSILYP+P+NF+LY DA +F++ L +G Y L VY+ G
Sbjct: 365 RAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSG 424
Query: 425 VPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVC 484
PP++ V AL ++T+ VPP LPAALT G +YAQ+RLKK+ IFCISPQRIN+CGQ+NLVC
Sbjct: 425 EPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVC 484
Query: 485 FDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQ 544
FDKTGTLT DGLDLWG V N FQE HSFASGQA+PW PLCAAMASCHSLILL+GTIQ
Sbjct: 485 FDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQ 544
Query: 545 GDPLDLKMFEGTAWKMEDCIVD-SCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPFSSS 603
GDPLDLKMFE T W+M D K + + ++KP AS+ PVE I L QFPFSS+
Sbjct: 545 GDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSA 604
Query: 604 LQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHK 663
LQRM+VI Q G + +MKGAPE VA FC+ ETVP +F EL+ YT QGFRVIALA+K
Sbjct: 605 LQRMTVIVQEMGGDRL-AFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYK 663
Query: 664 TLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNL 723
K+ N L RE VES+L FLGLLI+ENRLK+ETK VL+EL ARIRTVMITGDNL
Sbjct: 664 --KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNL 721
Query: 724 QTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQE-TGPGKKEIYMHTGNS 782
QTAITVA+ S M+ +VI++EA+E AS++W LVE ++ G ++ Y++ +
Sbjct: 722 QTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDE 781
Query: 783 STPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLN 842
+ +G GS YHFA++GKS+ VI QHF+SLLPKIL+NGT+FARMSPGQKSSL+EEFQKL+
Sbjct: 782 VSDKGREGS-YHFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLD 840
Query: 843 YYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSS 902
Y+VGMCGDGANDCGALK AH GISLSEQEASVASPFTSKT NI+CVPHLI+EGRAALV+S
Sbjct: 841 YFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTS 900
Query: 903 FGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPY 962
F +FKY+ +Y +IQ++ LLLYW+ NYQ+L QD+AIT ++ +TM+ AYPKL P+
Sbjct: 901 FCMFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPF 960
Query: 963 RPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQ--SNFST 1020
RPAG+L+SPPLLLS+ N S + I+ F+ V++QPWY V +S C + N+ S +
Sbjct: 961 RPAGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWY-SVEIHSACTVQNESISELTM 1019
Query: 1021 NVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSF 1080
+ + N+T SFE TT+W + TIN ITVA +FSKGKPFR+P YTNYIF
Sbjct: 1020 SPTAPEKMESNST-----FTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIFVL 1074
Query: 1081 LLLAALGLTIFILFSDFQVIYRGMELIPTITSWRVLILVVALTQFCVAFFVEDSILQNHE 1140
+L+ LG+ +FILF+D +YR ++L+ T WR I+++ F V+ E+++++N
Sbjct: 1075 VLIIQLGVCLFILFADIPELYRRLDLLCTPVLWRASIVIMLSLNFIVSLVAEEAVIENRA 1134
Query: 1141 LWLLIKREFGFYSKSQYRTWQKKLAEDSTWPPINRTDYSG---DGKNGFYINGGYESHEQ 1197
LW++IKR FG+ SKSQYR WQ+ LA D +WPP+N+T +S G+ Y N +ES+E+
Sbjct: 1135 LWMMIKRCFGYQSKSQYRIWQRDLANDPSWPPLNQTSHSDMPECGRGVSYSNPVFESNEE 1194
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 905 bits (2338), Expect = 0.0
Identities = 505/1219 (41%), Positives = 749/1219 (61%), Gaps = 64/1219 (5%)
Query: 7 KDHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVWANCIPC 66
++ R +NQG+EDE+E++GY + A + + + G LLL+ YW P+WRV A C+
Sbjct: 3 REERKTINQGQEDEMEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRA 62
Query: 67 PLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSK-KWEESLVADRHSV-------- 117
+++ + VLLRTTDEF+ + K+ L L T +PVS K + +++ H+V
Sbjct: 63 AIKDCEVVLLRTTDEFKMWFCAKIRVLSLET--YPVSSPKSMSNKLSNGHAVCLIENPTE 120
Query: 118 -----INQALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLT 172
I++ ++R ++Y WND F + L++ SC+ I++ GLT
Sbjct: 121 ENRHRISKYSQTESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLT 180
Query: 173 SEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIII 232
R+L+ G N I V++ ++KLL+K+VLNPFY+FQ F++ LW + Y Y++AI++
Sbjct: 181 KGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVV 240
Query: 233 LTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGK 292
++++SIV S+Y +R+Q V LH++V H+ V+V++ ++ +EE+ S LVPGD++++P
Sbjct: 241 MSIVSIVSSLYSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLN 300
Query: 293 FSL-PCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPW---KCHSLEDYRKHVLF 348
++ PCDAVLI+G+C+VNE MLTGES+PVTKT LP + + ++ E +++H LF
Sbjct: 301 GTIMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLF 360
Query: 349 CGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACL 408
CGT VIQ + V+A+V++TG++T+KG LVRSILYP+P +FKLY DA+ F++ L +
Sbjct: 361 CGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAV 420
Query: 409 GVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFC 468
+GF Y + + + V + +L ++T+TVPP LPAA+T G VYAQ+RLKK IFC
Sbjct: 421 AGIGFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFC 480
Query: 469 ISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPLCA 528
ISPQRIN+CGQ+NLVCFDKTGTLTEDGLDLWG + F + + S A
Sbjct: 481 ISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQFVA 540
Query: 529 AMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPK----- 583
MA+CHSL + G + GDPLDLKMFE W +E+ + + + PK
Sbjct: 541 CMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPE 600
Query: 584 ---ASKSPVEA--------IITLCQFPFSSSLQRMSVIAQLAGENHFHVYMKGAPEMVAR 632
A +E I + QFPFSS+LQRMSV+A++ G+ YMKGAPE +A
Sbjct: 601 STPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAG 660
Query: 633 FCRSETVPKNFPQELRSYTVQGFRVIALAHKTLKMG-NLSEVEHLAREKVESELTFLGLL 691
C+ ETVP +F L +T QGFRVIALAH+ L+ +V++++R+ +E+ + F+GL+
Sbjct: 661 LCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLI 720
Query: 692 IMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPE 751
IM+N+LK+ET VL++L +A IRTVM+TGD++ TA++VA++ MI P +VII EA P+
Sbjct: 721 IMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPK 780
Query: 752 EFVPASVTWQLVEN--QETGPGK--------KEIYMHTGNSSTPRGEGGSCYHFAMSGKS 801
+ A + W ++ Q + P K ++ + R YHFAM+GKS
Sbjct: 781 DGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTR------YHFAMNGKS 834
Query: 802 YQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAA 861
+ VI +HF L+PK++++GTVFARM+P QK+ LIE Q ++Y+VGMCGDGANDCGALK A
Sbjct: 835 FSVILEHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRA 894
Query: 862 HAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISAL 921
H GISLSE EASVASPFTSKT +I CVP+LIREGRAAL++SF VFK++ +Y IIQ+ S
Sbjct: 895 HGGISLSELEASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVT 954
Query: 922 LLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLSIFLNS 981
LLY L G++Q+L D+AI L+V TMS A+ +L RP L+S LL S+ L+
Sbjct: 955 LLYSILSNLGDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSV-LSQ 1013
Query: 982 CFSCI-VQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIPGSIL 1040
CI Q F +VKQQPWY + S+ S F + ++ L +I
Sbjct: 1014 IIICIGFQSLGFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVD----NETELDEHNIQ 1069
Query: 1041 SFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSDFQVI 1100
++E TT++ I++ Y+ VA FSKGKPFR+P Y NY F F ++ +FI+ +
Sbjct: 1070 NYENTTVFFISSFQYLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASV 1129
Query: 1101 YRGMELIPTITSWRVLILVVALTQFCVAFFVEDSILQNHEL---WLLIKREFGFYSKSQY 1157
+ ++++ WRV +L++ L V+ VE+S+ + + W L R+ K++Y
Sbjct: 1130 DQVLQIVCVPYQWRVTMLIIVLVNAFVSITVEESVDRWGKCCLPWALGCRK--KTPKAKY 1187
Query: 1158 RTWQKKLAEDSTWPPINRT 1176
++L D WPP +T
Sbjct: 1188 MYLAQELLVDPEWPPKPQT 1206
>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
Length = 1180
Score = 764 bits (1972), Expect = 0.0
Identities = 468/1171 (39%), Positives = 661/1171 (56%), Gaps = 103/1171 (8%)
Query: 48 LLVFYWRPQWRVWANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKF------- 100
LL+F W+P W V PC L A+T+++ D+ + +F + + T
Sbjct: 62 LLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQ--LFTVQVQTEAIGEGSLEP 119
Query: 101 -PVSKK----------------WEESLVADRHSVINQALIKPELKLRCMEVQKIRYVWND 143
P S+ W+++ A H + + LR Q RY+W +
Sbjct: 120 SPQSQAEDGRSQAAVGAVPEGAWKDT--AQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIE 177
Query: 144 LEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQV 203
++ F +V LL+ SC D+H++ GL+ ++Q VR+ + GPN I + ++ +LLV +
Sbjct: 178 TQQAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEA 236
Query: 204 LNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQ 263
LNP+Y FQAF++ LWL+ Y Y++ I +++ ISI LS+Y R+QS L ++V K+
Sbjct: 237 LNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMV----KLS 292
Query: 264 VTIIVKDKGLEE--LESRLLVPGDILILPGKFSL-PCDAVLIDGSCVVNEGMLTGESIPV 320
+ + V G EE ++S LVPGD L+LP + L PCDA L+ G C+VNE LTGESIPV
Sbjct: 293 MRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPV 352
Query: 321 TKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDL 380
KT LP E P+ E +R+H LFCGT ++Q + V AVV +TG+ TAKG L
Sbjct: 353 LKTALP--EGLGPY---CAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGL 407
Query: 381 VRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTV 440
V SIL+PRP+NFK Y + KF+ L+ L ++G Y++ + + VP + V AL L+TV
Sbjct: 408 VSSILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTV 467
Query: 441 TVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWG 500
VPP LPAA+T+ +YAQ RL+++ IFCI P RIN+ G++ LVCFDKTGTLTEDGLD+ G
Sbjct: 468 VVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMG 527
Query: 501 TVPTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKM 560
VP F + +P PL A+A+CH+L L T GDP+DLKM E T W +
Sbjct: 528 VVPLKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVL 585
Query: 561 EDCIVDSCKFGTSVSNIIKPGP-----KASKSPVEAIITLCQFPFSSSLQRMSVIAQLAG 615
E+ FGT V +++P +A + P + L +FPFSS+LQRMSV+ G
Sbjct: 586 EEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPG 645
Query: 616 ENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTLK-MGNLSEVE 674
Y+KG+PE+VA C ETVP +F Q L+SYT G+RV+ALA K L + +L +
Sbjct: 646 ATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQ 705
Query: 675 HLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSE 734
L R+ VE +L+ LGLL+M N LK +T V++ L RIR VM+TGDNLQTA+TVA+
Sbjct: 706 QLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCG 765
Query: 735 MIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYH 794
M+ P +IIV A PE PAS+ + +E+ G K+ + P H
Sbjct: 766 MVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSR---H 822
Query: 795 FAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGAND 854
A+SG ++ +I +HF LLPK+LV GTVFARM+P QK+ L+ E QKL Y VGMCGDGAND
Sbjct: 823 LALSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGAND 882
Query: 855 CGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGI 914
CGALKAA GISLS+ EASV SPFTS +I+CVP +IREGR +L +SF VFKY+ +Y +
Sbjct: 883 CGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSL 942
Query: 915 IQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLL 974
QFIS L+LY G+ Q+L D+ IT V + MS T L RP G LLS P+L
Sbjct: 943 TQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVL 1002
Query: 975 LSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATL 1034
S+ L VQ+ + QPW+ V L R
Sbjct: 1003 SSLLLQMVLVTGVQLGGYFLTLAQPWF--------------------VPLNR-----TVA 1037
Query: 1035 IPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILF 1094
P ++ ++E T ++ +++ Y+ +A SKG PFR+P+YTN F L AL L +L
Sbjct: 1038 APDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPF----LVALALLSSVLV 1093
Query: 1095 SDFQVIYRGMELIP------------TITSWRVLILVVALTQFCVAFFVEDSILQNHELW 1142
G+ L+P T T +++L+L + F AF +E S+L
Sbjct: 1094 --------GLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLE-SVLDQCLPA 1144
Query: 1143 LLIKREFGFYSKSQYRTWQKKLAEDSTWPPI 1173
L + SK +++ +++LAE WPP+
Sbjct: 1145 CLRRLRPKRASKKRFKQLERELAE-QPWPPL 1174
>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
Length = 1175
Score = 763 bits (1970), Expect = 0.0
Identities = 470/1169 (40%), Positives = 659/1169 (56%), Gaps = 104/1169 (8%)
Query: 48 LLVFYWRPQWRVWANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWE 107
LL+F W+P W V PC L A+T+++ D K+ L T++ E
Sbjct: 62 LLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD-------KEDSSWQLFTVQVQTEAIGE 114
Query: 108 ESLVADRHSVI----NQALI------------------KPELKLRCMEVQKIRYVWNDLE 145
SL S +QA + + + LR Q RY+W + +
Sbjct: 115 GSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQ 174
Query: 146 KRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLN 205
+ F +V LL+ SC D+H++ GL+ ++Q VR+ + GPN I + ++ +LLV + LN
Sbjct: 175 QAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
Query: 206 PFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVT 265
P+Y FQAF++ LWL+ Y Y++ I +++ ISI LS+Y R+QS L ++V K+ +
Sbjct: 234 PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMV----KLSMR 289
Query: 266 IIVKDKGLEE--LESRLLVPGDILILPGKFSL-PCDAVLIDGSCVVNEGMLTGESIPVTK 322
+ V G EE ++S LVPGD L+LP + L PCDA L+ G C+VNE LTGESIPV K
Sbjct: 290 VCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLK 349
Query: 323 TPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVR 382
T LP E P+ E +R+H LFCGT ++Q + V AVV +TG+ TAKG LV
Sbjct: 350 TALP--EGLGPY---CAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVS 404
Query: 383 SILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTV 442
SIL+PRP+NFK Y + KF+ L+ L ++G Y++ + + VP + V AL L+TV V
Sbjct: 405 SILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVV 464
Query: 443 PPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTV 502
PP LPAA+T+ +YAQ RL+++ IFCI P RIN+ G++ LVCFDKTGTLTEDGLD+ G V
Sbjct: 465 PPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVV 524
Query: 503 PTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMED 562
P F + +P PL A+A+CH+L L T GDP+DLKM E T W +E+
Sbjct: 525 PLKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEE 582
Query: 563 CIVDSCKFGTSVSNIIKPGP-----KASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGEN 617
FGT V +++P +A + P + L +FPFSS+LQRMSV+ G
Sbjct: 583 EPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGAT 642
Query: 618 HFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTLK-MGNLSEVEHL 676
Y+KG+PE+VA C ETVP +F Q L+SYT G+RV+ALA K L + +L + L
Sbjct: 643 QPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQL 702
Query: 677 AREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMI 736
R+ VE +L+ LGLL+M N LK +T V++ L RIR VM+TGDNLQTA+TVA+ M+
Sbjct: 703 TRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMV 762
Query: 737 PPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFA 796
P +IIV A PE PAS+ + +E+ G K+ + P H A
Sbjct: 763 APQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSR---HLA 819
Query: 797 MSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCG 856
+SG ++ +I +HF LLPK+LV GTVFARM+P QK+ L+ E QKL Y VGMCGDGANDCG
Sbjct: 820 LSGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCG 879
Query: 857 ALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQ 916
ALKAA GISLS+ EASV SPFTS +I+CVP +IREGR +L +SF VFKY+ +Y + Q
Sbjct: 880 ALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQ 939
Query: 917 FISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLS 976
FIS L+LY G+ Q+L D+ IT V + MS T L RP G LLS P+L S
Sbjct: 940 FISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSS 999
Query: 977 IFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIP 1036
+ L VQ+ + QPW+ V L R P
Sbjct: 1000 LLLQMVLVTGVQLGGYFLTLAQPWF--------------------VPLNR-----TVAAP 1034
Query: 1037 GSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSD 1096
++ ++E T ++ +++ Y+ +A SKG PFR+P+YTN F L AL L +L
Sbjct: 1035 DNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTNVPF----LVALALLSSVLV-- 1088
Query: 1097 FQVIYRGMELIP------------TITSWRVLILVVALTQFCVAFFVEDSILQNHELWLL 1144
G+ L+P T T +++L+L + F AF +E S+L L
Sbjct: 1089 ------GLVLVPGLLQGPLALRNITDTGFKLLLLGLVTLNFVGAFMLE-SVLDQCLPACL 1141
Query: 1145 IKREFGFYSKSQYRTWQKKLAEDSTWPPI 1173
+ SK +++ +++LAE WPP+
Sbjct: 1142 RRLRPKRASKKRFKQLERELAE-QPWPPL 1169
>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
Length = 1158
Score = 712 bits (1839), Expect = 0.0
Identities = 430/1059 (40%), Positives = 594/1059 (56%), Gaps = 117/1059 (11%)
Query: 48 LLVFYWRPQWRVWANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWE 107
LL+F W+P W V PC L A+T+++ D K+ L T++ E
Sbjct: 62 LLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD-------KEDSSWQLFTVQVQTEAIGE 114
Query: 108 ESLVADRHSVI----NQALI------------------KPELKLRCMEVQKIRYVWNDLE 145
SL S +QA + + + LR Q RY+W + +
Sbjct: 115 GSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQ 174
Query: 146 KRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLN 205
+ F +V LL+ SC D+H++ GL+ ++Q VR+ + GPN I + ++ +LLV + LN
Sbjct: 175 QAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
Query: 206 PFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVT 265
P+Y FQAF++ LWL+ Y Y++ I +++ ISI LS+Y R+QS L ++V K+ +
Sbjct: 234 PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMV----KLSMR 289
Query: 266 IIVKDKGLEE--LESRLLVPGDILILPGKFSL-PCDAVLIDGSCVVNEGMLTGESIPVTK 322
+ V G EE ++S LVPGD L+LP + L PCDA L+ G C+VNE LTGESIPV K
Sbjct: 290 VCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLK 349
Query: 323 TPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVR 382
T LP E P+ E +R+H LFCGT ++Q + V AVV +TG+ TAKG LV
Sbjct: 350 TALP--EGLGPY---CAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVS 404
Query: 383 SILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTV 442
SIL+PRP+NFK Y + KF+ L+ L ++G Y++ + + VP + V AL L+TV V
Sbjct: 405 SILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVV 464
Query: 443 PPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTV 502
PP LPAA+T+ +YAQ RL+++ IFCI P RIN+ G++ LVCFDKTGTLTEDGLD+ G V
Sbjct: 465 PPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVV 524
Query: 503 PTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMED 562
P F + +P PL A+A+CH+L L T GDP+DLKM E T W +E+
Sbjct: 525 PLKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEE 582
Query: 563 CIVDSCKFGTSVSNIIK-----PGPKASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGEN 617
FGT V +++ P +A + P + L +FPFSS+LQRMSV+ G
Sbjct: 583 EPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGAT 642
Query: 618 HFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTL-KMGNLSEVEHL 676
Y+KG+PE+VA C ETVP +F Q L+SYT G+RV+ALA K L + +L + L
Sbjct: 643 QPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQL 702
Query: 677 AREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMI 736
R+ VE +L+ LGLL+M N LK +T V++ L RIR VM+TGDNLQTA+TVA+ M+
Sbjct: 703 TRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMV 762
Query: 737 PPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFA 796
P +IIV A PE PAS+ + +E+ G
Sbjct: 763 APQEHLIIVHATHPERGQPASLEFLPMESPTAVNG------------------------- 797
Query: 797 MSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCG 856
K+LV GTVFARM+P QK+ L+ E QKL Y VGMCGDGANDCG
Sbjct: 798 -----------------VKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCG 840
Query: 857 ALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQ 916
ALKAA GISLS+ EASV SPFTS +I+CVP +IREGR +L +SF VFKY+ +Y + Q
Sbjct: 841 ALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQ 900
Query: 917 FISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLS 976
FIS L+LY G+ Q+L D+ IT V + MS T L RP G LLS P+L S
Sbjct: 901 FISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSS 960
Query: 977 IFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIP 1036
+ L VQ+ + QPW+ V L R P
Sbjct: 961 LLLQMVLVTGVQLGGYFLTLAQPWF--------------------VPLNR-----TVAAP 995
Query: 1037 GSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTN 1075
++ ++E T ++ +++ Y+ +A SKG PFR+P+YTN
Sbjct: 996 DNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1034
>gi|170016077 ATPase type 13A1 [Homo sapiens]
Length = 1204
Score = 267 bits (682), Expect = 5e-71
Identities = 229/770 (29%), Positives = 363/770 (47%), Gaps = 84/770 (10%)
Query: 127 LKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPN 186
L++ E QKI+Y ++ LEK+ N+ S G SE + + G N
Sbjct: 167 LEVLSFEFQKIKYSYDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSEIRAAEKKF-GSN 225
Query: 187 AIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLR 246
E+ + +L ++ PF+VFQ F + LW Y YSV + + V ++
Sbjct: 226 KAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLV---AFEASLVQ 282
Query: 247 QQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILIL---PGKFSLPCDAVLID 303
QQ + + + NK + + + + + S +VPGDI+ + P + +PCD +L+
Sbjct: 283 QQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLR 342
Query: 304 GSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLE-DYRKHVLFCGTEVIQ------- 355
G C+V+E MLTGES+P K P+ E+ P + L+ D R HV+F GT+V+Q
Sbjct: 343 GRCIVDEAMLTGESVPQMKEPI---EDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKA 399
Query: 356 ---VKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMG 412
+KP G V A VL+TG+NT++G L+R+IL+ + F FI+FL +
Sbjct: 400 TTGLKPVDSGCV-AYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFL-----LV 453
Query: 413 FFYALGVYMY-HGV--PPKDTVTMAL---ILLTVTVPPVLPAALTIGNVYAQKRLKKKKI 466
F A Y++ G P ++ + L ++LT VPP LP L++ + L K +
Sbjct: 454 FAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYM 513
Query: 467 FCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPL 526
+C P RI G++ + CFDKTGTLT D L + G D + P S +
Sbjct: 514 YCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDG----------KEVTPVSSI 563
Query: 527 CA----AMASCHSLILLN-GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPG 581
A+ASCHSL+ L+ GT+ GDPL+ M W + D F S+ G
Sbjct: 564 PVETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTK---DEKVFPRSIKT---QG 617
Query: 582 PKASKSPVEAIITLCQFPFSSSLQRMSVIAQL----AGENHFHVYMKGAPEMVARFCRSE 637
K + +F F+S+L+RMSV+A + + + +KGAPE +
Sbjct: 618 LKIHQ----------RFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQ- 666
Query: 638 TVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRL 697
P ++ + +G RV+AL +K L + + RE +E L F+G +++ L
Sbjct: 667 -CPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIVVSCPL 725
Query: 698 KKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPAS 757
K ++K V++E+ A R VMITGDN TA VA+ I +I+ +P
Sbjct: 726 KADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLIL----QPPSEKGRQ 781
Query: 758 VTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKIL 817
W+ ++ G + + G+ E Y ++G + L +++
Sbjct: 782 CEWRSID------GSIVLPLARGSPKALALE----YALCLTGDGLAHLQATDPQQLLRLI 831
Query: 818 VNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISL 867
+ VFAR++P QK +I ++L Y MCGDG ND GALK A G++L
Sbjct: 832 PHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
Score = 67.8 bits (164), Expect = 6e-11
Identities = 66/268 (24%), Positives = 117/268 (43%), Gaps = 29/268 (10%)
Query: 871 EASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALLLYWQLQLF 930
+AS+A+PFTSK ++IQC+ H+I++GR LV++ +FK L + +I S +LY + F
Sbjct: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
Query: 931 GNYQYLMQDVAITLMVC-LTMSSTHAYPKLAPYRPAGQLLSPPLLLSIFLNSCFSCIVQI 989
++Q +Q + L C L +S + L+ RP + + +L++ L
Sbjct: 1013 SDFQATLQ--GLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVML---------- 1060
Query: 990 SAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIPGSILSFETTTLWP 1049
F++ + VY Y E + V L + + +L+ ++
Sbjct: 1061 QFFVH-----FLSLVYLYREAQARSPEKQEQFVDLYKEF--EPSLVNSTVYIMAMAMQMA 1113
Query: 1050 ITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSDFQVIYRGMELIPT 1109
INY KG PF + + N + L +L I +L L+
Sbjct: 1114 TFAINY--------KGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDI 1165
Query: 1110 ITSWRVLILVVALTQFCVAFFVEDSILQ 1137
++++I V L FC+A + D +LQ
Sbjct: 1166 PVEFKLVIAQVLLLDFCLA-LLADRVLQ 1192
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 129 bits (325), Expect = 1e-29
Identities = 204/911 (22%), Positives = 361/911 (39%), Gaps = 130/911 (14%)
Query: 127 LKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSN-SCSDIHQTFG----LGLTSEEQEVRRL 181
LK C+E++K + ++ FQK L+D S ++ + +G +GL+S
Sbjct: 34 LKNNCLELKKKNH-----KEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLA 88
Query: 182 VCGPNAIEVEIQ-PIWKLLVKQVLNPFYVFQAFTLTL-WLSQGYIEYS---------VAI 230
GPN++ Q P +KQ++ F + L W++ G I+YS V +
Sbjct: 89 RDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYG-IQYSSDKSASLNNVYL 147
Query: 231 IILTVISIVLSVYDLRQQSVKLHNLVEDHNKV--QVTIIVKDKGLEELESRLLVPGDILI 288
+ + ++L+ Q K N++ NK+ Q ++++D + + S LV GDI+
Sbjct: 148 GCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVE 207
Query: 289 LPGKFSLPCDA-VLIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVL 347
+ G +P D VL C V+ LTGES P ++ EN + K++
Sbjct: 208 VKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLE---------TKNIC 258
Query: 348 FCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDL--VRSILYPRPLNFKLYSDAFKFIVFL 405
F T ++ G V +V+ TG T G + + S + + + F IV
Sbjct: 259 FYSTTCLE------GTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAG 312
Query: 406 ACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKK 465
+ + F+ + V + + V D++ + ++ VP L A +T+ KR+ KK
Sbjct: 313 VAVSIGILFFIIAVSLKYQV--LDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKN 370
Query: 466 IFCISPQRINMCGQINLVCFDKTGTLTEDGL---DLW--GTVPTADNCFQEAHSFASGQA 520
+ + + G +++C DKTGTLT++ + LW + AD ++ +
Sbjct: 371 CLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSS 430
Query: 521 VPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKP 580
W+ L + C+ G + P+ K G A E ++ KF + +
Sbjct: 431 RTWASLSKIITLCNRAEFKPGQ-ENVPIMKKAVIGDA--SETALL---KFSEVILGDVME 484
Query: 581 GPKASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGEN--HFHVYMKGAPEMVARFCRS-- 636
K ++ + + PF+S+ + I ++ + F + MKGAPE + C +
Sbjct: 485 IRKRNRK-------VAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIM 537
Query: 637 ---------ETVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEVEHL---AREKVESE 684
++ K F G RV+ H L E A S
Sbjct: 538 INGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSN 597
Query: 685 LTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVII 744
L F+GLL M + + + + A I+ +M+TGD+ TA +AK+ +I S+ +
Sbjct: 598 LCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETV- 656
Query: 745 VEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQV 804
E H N + + ++G +
Sbjct: 657 -----------------------------EDIAHRLNIAVEQVNKRDAKAAVVTGMELK- 686
Query: 805 IFQHFNSLLPKILVN--GTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAH 862
+ L +IL N VFAR SP QK ++E Q+ + V + GDG ND ALK A
Sbjct: 687 --DMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKAD 744
Query: 863 AGISL---SEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFIS 919
GI++ A A+ N + + EGR F K Y + + I+
Sbjct: 745 IGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLI----FDNLKKTIAYSLTKNIA 800
Query: 920 AL---LLYWQLQL---FGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRP----AGQLL 969
L L+Y + L G L D+ ++ + ++ A + +P +L+
Sbjct: 801 ELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLV 860
Query: 970 SPPLLLSIFLN 980
+ PL + +L+
Sbjct: 861 NQPLAVYSYLH 871
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 123 bits (308), Expect = 1e-27
Identities = 180/805 (22%), Positives = 324/805 (40%), Gaps = 121/805 (15%)
Query: 114 RHSVINQALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTS 173
+ +I + ++K E + R ME K V +D + LE+ ++ + T G
Sbjct: 22 KKGLIKKKMVKREKQKRNMEELKKEVVMDDHKLT------LEELSTKYSVDLTKGHSHQR 75
Query: 174 EEQEVRRLVCGPNAIEVE-IQPIWKLLVKQVLNPFYVFQAFTLTLWLSQ--GYIEYSVAI 230
++ + R GPN + P W KQ+ F F+L LW ++ YS+ I
Sbjct: 76 AKEILTR--GGPNTVTPPPTTPEWVKFCKQL------FGGFSLLLWTGAILCFVAYSIQI 127
Query: 231 --------------IILTVISIVLSVYDLRQQSVKLHNLVEDHNKV-QVTIIVKDKGLEE 275
I+L+V+ IV + Q++ + N V Q ++++ +
Sbjct: 128 YFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQ 187
Query: 276 LESRLLVPGDILILPGKFSLPCDAVLIDGS-CVVNEGMLTGESIPVTKTPLPQMENTMPW 334
+ + +V GD++ + G +P D LI C V+ LTGES P +++P EN +
Sbjct: 188 INVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLE- 246
Query: 335 KCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSI----LYPRPL 390
+++ F T ++ G R +V+ TG +T G + + P+
Sbjct: 247 --------TRNICFFSTNCVE------GTARGIVIATGDSTVMGRIASLTSGLAVGQTPI 292
Query: 391 NFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAAL 450
++ V LGV F+AL + + +G + + + ++ VP L A +
Sbjct: 293 AAEIEHFIHLITVVAVFLGVT--FFALSLLLGYGW--LEAIIFLIGIIVANVPEGLLATV 348
Query: 451 TIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGL---DLW--GTVPTA 505
T+ KR+ +K + + + G + +C DKTGTLT++ + +W TV A
Sbjct: 349 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEA 408
Query: 506 DNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDCIV 565
D ++ + + W L C+ + + L + T E ++
Sbjct: 409 DTTEEQTGKTFTKSSDTWFMLARIAGLCNR---ADFKANQEILPIAKRATTGDASESALL 465
Query: 566 DSCKFG-TSVSNIIKPGPKASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGENHFHVYMK 624
+ +SV+ + + PK ++ P S++ +MS+ + + MK
Sbjct: 466 KFIEQSYSSVAEMREKNPKVAEIPFN----------STNKYQMSIHLREDSSQTHVLMMK 515
Query: 625 GAPEMVARFC-----------RSETVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEV 673
GAPE + FC ++ + + F G RV+ L + S+
Sbjct: 516 GAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLP-SSFSKG 574
Query: 674 EHLAREKVE---SELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVA 730
+++ L F+GL+ M + + + + A I+ +M+TGD+ TA +A
Sbjct: 575 FPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIA 634
Query: 731 KNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGG 790
K II E E E V A + ++ ++ K I +H G
Sbjct: 635 KGVG--------IISEGTETAEEVAARL--KIPISKVDASAAKAIVVH-----------G 673
Query: 791 SCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGD 850
+ S + Q++ H P+I VFAR SP QK ++E Q+L V + GD
Sbjct: 674 AELKDIQSKQLDQILQNH-----PEI-----VFARTSPQQKLIIVEGCQRLGAVVAVTGD 723
Query: 851 GANDCGALKAAHAGISLSEQEASVA 875
G ND ALK A GI++ + V+
Sbjct: 724 GVNDSPALKKADIGIAMGISGSDVS 748
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 115 bits (288), Expect = 3e-25
Identities = 166/751 (22%), Positives = 294/751 (39%), Gaps = 116/751 (15%)
Query: 170 GLTSEEQEVRRLVCGPNAIEVE-IQPIWKLLVKQVLNPFYVFQAFTLTLWLSQ--GYIEY 226
GLT++ + GPNA+ P W +Q+ F F++ LW+ ++ Y
Sbjct: 60 GLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQL------FGGFSILLWIGAILCFLAY 113
Query: 227 SVAI--------------IILTVISIVLSVYDLRQQSVKLHNLVEDHNKV-QVTIIVKDK 271
+ ++L + IV + Q++ + N V Q +++++
Sbjct: 114 GIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREG 173
Query: 272 GLEELESRLLVPGDILILPGKFSLPCDAVLIDG-SCVVNEGMLTGESIPVTKTPLPQMEN 330
++ + +V GD++ + G +P D +I C V+ LTGES P T++P EN
Sbjct: 174 EKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHEN 233
Query: 331 TMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPL 390
+ +++ F T ++ G R +V+ TG T G +
Sbjct: 234 PLE---------TRNICFFSTNCVE------GTARGIVIATGDRTVMGRIATLASGLEVG 278
Query: 391 NFKLYSDAFKFIVFLACLGV-MGF-FYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPA 448
+ + FI + + V +G F+ L + + G + V + ++ VP L A
Sbjct: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLIL--GYSWLEAVIFLIGIIVANVPEGLLA 336
Query: 449 ALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGL---DLW--GTVP 503
+T+ KR+ +K + + + G + +C DKTGTLT++ + +W +
Sbjct: 337 TVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIH 396
Query: 504 TADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWK--ME 561
AD ++ + ++ W+ L C+ + G + + + G A + +
Sbjct: 397 EADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQ-ENISVSKRDTAGDASESALL 455
Query: 562 DCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGENHFHV 621
CI SC SV + PK + + PF+S+ + I + HV
Sbjct: 456 KCIELSC---GSVRKMRDRNPK-----------VAEIPFNSTNKYQLSIHEREDSPQSHV 501
Query: 622 -YMKGAPEMVARFC-----RSETVPKN------FPQELRSYTVQGFRVIALAHKTLKMGN 669
MKGAPE + C + + +P + F G RV+ L G
Sbjct: 502 LVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGK 561
Query: 670 LSEVEHLAREKVE---SELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTA 726
+++ +L F+GL+ M + + + + A I+ +M+TGD+ TA
Sbjct: 562 FPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITA 621
Query: 727 ITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPR 786
+AK +I G++ + E + I M N PR
Sbjct: 622 KAIAKGVGIISEGNETV-----------------------EDIAARLNIPMSQVN---PR 655
Query: 787 GEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGT--VFARMSPGQKSSLIEEFQKLNYY 844
E +C K + L +IL N T VFAR SP QK ++E Q+
Sbjct: 656 -EAKACVVHGSDLKDMT------SEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAI 708
Query: 845 VGMCGDGANDCGALKAAHAGISLSEQEASVA 875
V + GDG ND ALK A GI++ + V+
Sbjct: 709 VAVTGDGVNDSPALKKADIGIAMGISGSDVS 739
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 115 bits (287), Expect = 3e-25
Identities = 183/810 (22%), Positives = 308/810 (38%), Gaps = 150/810 (18%)
Query: 184 GPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQG------YIEYSVAIIILTVIS 237
G +E+ I+ LLV+ +L + +F L W +G ++E V ++IL V +
Sbjct: 46 GKTLLELVIEQFEDLLVRILLLAACI--SFVLA-WFEEGEETITAFVEPFVILLIL-VAN 101
Query: 238 IVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGKFSLPC 297
++ V+ R + L E ++ K ++ ++++ +VPGDI+ + +P
Sbjct: 102 AIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPA 161
Query: 298 DAVLIDGSCV---VNEGMLTGESIPVTK--TPLPQMENTMPWKCHSLEDYRKHVLFCGTE 352
D L V++ +LTGES+ V K P+P ++ +K++LF GT
Sbjct: 162 DIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPR--------AVNQDKKNMLFSGTN 213
Query: 353 VIQVKPSGQGPVRAVVLQTGYNTAKG----DLVRSILYPRPLNFKL--YSDAFKFIVFLA 406
+ K G VV+ TG NT G ++V + PL KL + + ++ L
Sbjct: 214 IAAGKAMG------VVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLI 267
Query: 407 CLGV----MGFF--------YALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGN 454
C+ V +G F + G Y + A+ L +P LPA +T
Sbjct: 268 CIAVWIINIGHFNDPVHGGSWIRGAIYYFKI--------AVALAVAAIPEGLPAVITTCL 319
Query: 455 VYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTV----PTADNCFQ 510
+R+ KK S + G +++C DKTGTLT + + + D C
Sbjct: 320 ALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSL 379
Query: 511 EAHSFASGQAVPWSPLCA--AMASCH------SLILLNGTIQGDPLDLKMFEGTAWKMED 562
+ P + +CH L + LD +G K+ +
Sbjct: 380 NEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGE 439
Query: 563 -------CIVDSCK-FGTSVSNIIK-PGPKASKSPVEAIITL-CQFPFSSSLQRMSVIA- 611
C+V+ F T + + K A S ++ ++ FS + MSV
Sbjct: 440 ATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCT 499
Query: 612 --QLAGENHFHVYMKGAPEMVARFCR-----SETVPKNFPQELRSYTV--------QGFR 656
+ + + +++KGAPE V C S VP + + +V R
Sbjct: 500 PNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLR 559
Query: 657 VIALA--HKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIR 714
+ALA L+ + + K E+ LTF+G + M + + E +K +A IR
Sbjct: 560 CLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIR 619
Query: 715 TVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKE 774
+MITGDN TA+ + + ++ I DE VT + +E
Sbjct: 620 VIMITGDNKGTAVAICR---------RIGIFGQDE-------DVTSKAFTGREF------ 657
Query: 775 IYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSL 834
+ P + +C +N FAR+ P KS +
Sbjct: 658 ------DELNPSAQRDAC-------------------------LNARCFARVEPSHKSKI 686
Query: 835 IEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTSKTTNIQCVPHLI 892
+E Q + M GDG ND ALK A GI++ A AS N + +
Sbjct: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAV 746
Query: 893 REGRAALVSSFGVFKYLTMYGIIQFISALL 922
EGRA + +YL + + + L
Sbjct: 747 EEGRAIYNNMKQFIRYLISSNVGEVVCIFL 776
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
[Homo sapiens]
Length = 1042
Score = 115 bits (287), Expect = 3e-25
Identities = 183/810 (22%), Positives = 308/810 (38%), Gaps = 150/810 (18%)
Query: 184 GPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQG------YIEYSVAIIILTVIS 237
G +E+ I+ LLV+ +L + +F L W +G ++E V ++IL V +
Sbjct: 46 GKTLLELVIEQFEDLLVRILLLAACI--SFVLA-WFEEGEETITAFVEPFVILLIL-VAN 101
Query: 238 IVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGKFSLPC 297
++ V+ R + L E ++ K ++ ++++ +VPGDI+ + +P
Sbjct: 102 AIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPA 161
Query: 298 DAVLIDGSCV---VNEGMLTGESIPVTK--TPLPQMENTMPWKCHSLEDYRKHVLFCGTE 352
D L V++ +LTGES+ V K P+P ++ +K++LF GT
Sbjct: 162 DIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPR--------AVNQDKKNMLFSGTN 213
Query: 353 VIQVKPSGQGPVRAVVLQTGYNTAKG----DLVRSILYPRPLNFKL--YSDAFKFIVFLA 406
+ K G VV+ TG NT G ++V + PL KL + + ++ L
Sbjct: 214 IAAGKAMG------VVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLI 267
Query: 407 CLGV----MGFF--------YALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGN 454
C+ V +G F + G Y + A+ L +P LPA +T
Sbjct: 268 CIAVWIINIGHFNDPVHGGSWIRGAIYYFKI--------AVALAVAAIPEGLPAVITTCL 319
Query: 455 VYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTV----PTADNCFQ 510
+R+ KK S + G +++C DKTGTLT + + + D C
Sbjct: 320 ALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSL 379
Query: 511 EAHSFASGQAVPWSPLCA--AMASCH------SLILLNGTIQGDPLDLKMFEGTAWKMED 562
+ P + +CH L + LD +G K+ +
Sbjct: 380 NEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGE 439
Query: 563 -------CIVDSCK-FGTSVSNIIK-PGPKASKSPVEAIITL-CQFPFSSSLQRMSVIA- 611
C+V+ F T + + K A S ++ ++ FS + MSV
Sbjct: 440 ATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCT 499
Query: 612 --QLAGENHFHVYMKGAPEMVARFCR-----SETVPKNFPQELRSYTV--------QGFR 656
+ + + +++KGAPE V C S VP + + +V R
Sbjct: 500 PNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLR 559
Query: 657 VIALA--HKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIR 714
+ALA L+ + + K E+ LTF+G + M + + E +K +A IR
Sbjct: 560 CLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIR 619
Query: 715 TVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKE 774
+MITGDN TA+ + + ++ I DE VT + +E
Sbjct: 620 VIMITGDNKGTAVAICR---------RIGIFGQDE-------DVTSKAFTGREF------ 657
Query: 775 IYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSL 834
+ P + +C +N FAR+ P KS +
Sbjct: 658 ------DELNPSAQRDAC-------------------------LNARCFARVEPSHKSKI 686
Query: 835 IEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTSKTTNIQCVPHLI 892
+E Q + M GDG ND ALK A GI++ A AS N + +
Sbjct: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAV 746
Query: 893 REGRAALVSSFGVFKYLTMYGIIQFISALL 922
EGRA + +YL + + + L
Sbjct: 747 EEGRAIYNNMKQFIRYLISSNVGEVVCIFL 776
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
sapiens]
Length = 939
Score = 114 bits (286), Expect = 4e-25
Identities = 177/818 (21%), Positives = 311/818 (38%), Gaps = 162/818 (19%)
Query: 149 QKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEV-EIQPIWKLLVKQVLNPF 207
+K L S S + GL E RR G N ++ E +P+WK + Q NP
Sbjct: 24 KKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPL 83
Query: 208 YVF--QAFTLTLWLSQGYIEYSVAIIILTVISIV-LSVYDLRQQSVKLHNLV--EDHNKV 262
+ + +++ + Q S+ + IL V+++ + Y + +L LV E H
Sbjct: 84 IMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--- 140
Query: 263 QVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAVLIDG-SCVVNEGMLTGESIPVT 321
V++ LE +R LVPGD + L +P D L + ++E LTGE+ P +
Sbjct: 141 ----CVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCS 196
Query: 322 KTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLV 381
K PQ P + R ++ F GT V G + VV+ TG N+ G++
Sbjct: 197 KVTAPQ-----PAATNGDLASRSNIAFMGTLV------RCGKAKGVVIGTGENSEFGEVF 245
Query: 382 RSILY------PRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMAL 435
+ + P + L F F G++G +G + G + T+++
Sbjct: 246 KMMQAEEAPKTPLQKSMDLLGKQLSFYSF----GIIGIIMLVGWLL--GKDILEMFTISV 299
Query: 436 ILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDG 495
L +P LP +T+ R+ KK+ + G N++C DKTGTLT++
Sbjct: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
Query: 496 LDLWGTVPTADNCFQE---------AHSFASGQAV------PWSPLCAAMASCHSLILLN 540
+ + + T+D E G V S + A C+ ++ N
Sbjct: 360 MTV-THIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRN 418
Query: 541 GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPF 600
T+ G P + G ++ +K G + + I ++PF
Sbjct: 419 NTLMGKPTE---------------------GALIALAMKMGLDGLQ---QDYIRKAEYPF 454
Query: 601 SSSLQRMSV--IAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVI 658
SS + M+V + + + +MKGA E V ++C + + + ++ T+ +
Sbjct: 455 SSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTT------YQSKGQTLTLTQQQRD 508
Query: 659 ALAHKTLKMGNLS-EVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVM 717
+ +MG+ V LA +LTFLGL+ + + + K + L + + M
Sbjct: 509 VYQQEKARMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKM 568
Query: 718 ITGDNLQTAITVA-------KNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGP 770
ITGD+ +TA+ +A K S+ + G ++ ++ + + VP +
Sbjct: 569 ITGDSQETAVAIASRLGLYSKTSQSV-SGEEIDAMDVQQLSQIVPKVAVF---------- 617
Query: 771 GKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQ 830
Y+ +H ++ + NG+V
Sbjct: 618 -------------------------------YRASPRHKMKIIKSLQKNGSV-------- 638
Query: 831 KSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASV---ASPFTSKTTNIQC 887
V M GDG ND ALKAA G+++ + V A+ + Q
Sbjct: 639 --------------VAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQT 684
Query: 888 VPHLIREGRAAL--VSSFGVFKYLTMYGIIQFISALLL 923
+ I EG+ + +F F+ T + IS L
Sbjct: 685 IMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
sapiens]
Length = 949
Score = 114 bits (286), Expect = 4e-25
Identities = 177/818 (21%), Positives = 311/818 (38%), Gaps = 162/818 (19%)
Query: 149 QKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEV-EIQPIWKLLVKQVLNPF 207
+K L S S + GL E RR G N ++ E +P+WK + Q NP
Sbjct: 24 KKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPL 83
Query: 208 YVF--QAFTLTLWLSQGYIEYSVAIIILTVISIV-LSVYDLRQQSVKLHNLV--EDHNKV 262
+ + +++ + Q S+ + IL V+++ + Y + +L LV E H
Sbjct: 84 IMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--- 140
Query: 263 QVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAVLIDG-SCVVNEGMLTGESIPVT 321
V++ LE +R LVPGD + L +P D L + ++E LTGE+ P +
Sbjct: 141 ----CVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCS 196
Query: 322 KTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLV 381
K PQ P + R ++ F GT V G + VV+ TG N+ G++
Sbjct: 197 KVTAPQ-----PAATNGDLASRSNIAFMGTLV------RCGKAKGVVIGTGENSEFGEVF 245
Query: 382 RSILY------PRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMAL 435
+ + P + L F F G++G +G + G + T+++
Sbjct: 246 KMMQAEEAPKTPLQKSMDLLGKQLSFYSF----GIIGIIMLVGWLL--GKDILEMFTISV 299
Query: 436 ILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDG 495
L +P LP +T+ R+ KK+ + G N++C DKTGTLT++
Sbjct: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
Query: 496 LDLWGTVPTADNCFQE---------AHSFASGQAV------PWSPLCAAMASCHSLILLN 540
+ + + T+D E G V S + A C+ ++ N
Sbjct: 360 MTV-THIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRN 418
Query: 541 GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPF 600
T+ G P + G ++ +K G + + I ++PF
Sbjct: 419 NTLMGKPTE---------------------GALIALAMKMGLDGLQ---QDYIRKAEYPF 454
Query: 601 SSSLQRMSV--IAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVI 658
SS + M+V + + + +MKGA E V ++C + + + ++ T+ +
Sbjct: 455 SSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTT------YQSKGQTLTLTQQQRD 508
Query: 659 ALAHKTLKMGNLS-EVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVM 717
+ +MG+ V LA +LTFLGL+ + + + K + L + + M
Sbjct: 509 VYQQEKARMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKM 568
Query: 718 ITGDNLQTAITVA-------KNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGP 770
ITGD+ +TA+ +A K S+ + G ++ ++ + + VP +
Sbjct: 569 ITGDSQETAVAIASRLGLYSKTSQSV-SGEEIDAMDVQQLSQIVPKVAVF---------- 617
Query: 771 GKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQ 830
Y+ +H ++ + NG+V
Sbjct: 618 -------------------------------YRASPRHKMKIIKSLQKNGSV-------- 638
Query: 831 KSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASV---ASPFTSKTTNIQC 887
V M GDG ND ALKAA G+++ + V A+ + Q
Sbjct: 639 --------------VAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQT 684
Query: 888 VPHLIREGRAAL--VSSFGVFKYLTMYGIIQFISALLL 923
+ I EG+ + +F F+ T + IS L
Sbjct: 685 IMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
sapiens]
Length = 888
Score = 114 bits (286), Expect = 4e-25
Identities = 177/818 (21%), Positives = 311/818 (38%), Gaps = 162/818 (19%)
Query: 149 QKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEV-EIQPIWKLLVKQVLNPF 207
+K L S S + GL E RR G N ++ E +P+WK + Q NP
Sbjct: 24 KKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPL 83
Query: 208 YVF--QAFTLTLWLSQGYIEYSVAIIILTVISIV-LSVYDLRQQSVKLHNLV--EDHNKV 262
+ + +++ + Q S+ + IL V+++ + Y + +L LV E H
Sbjct: 84 IMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--- 140
Query: 263 QVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAVLIDG-SCVVNEGMLTGESIPVT 321
V++ LE +R LVPGD + L +P D L + ++E LTGE+ P +
Sbjct: 141 ----CVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCS 196
Query: 322 KTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLV 381
K PQ P + R ++ F GT V G + VV+ TG N+ G++
Sbjct: 197 KVTAPQ-----PAATNGDLASRSNIAFMGTLV------RCGKAKGVVIGTGENSEFGEVF 245
Query: 382 RSILY------PRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMAL 435
+ + P + L F F G++G +G + G + T+++
Sbjct: 246 KMMQAEEAPKTPLQKSMDLLGKQLSFYSF----GIIGIIMLVGWLL--GKDILEMFTISV 299
Query: 436 ILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDG 495
L +P LP +T+ R+ KK+ + G N++C DKTGTLT++
Sbjct: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
Query: 496 LDLWGTVPTADNCFQE---------AHSFASGQAV------PWSPLCAAMASCHSLILLN 540
+ + + T+D E G V S + A C+ ++ N
Sbjct: 360 MTV-THIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRN 418
Query: 541 GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPF 600
T+ G P + G ++ +K G + + I ++PF
Sbjct: 419 NTLMGKPTE---------------------GALIALAMKMGLDGLQ---QDYIRKAEYPF 454
Query: 601 SSSLQRMSV--IAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVI 658
SS + M+V + + + +MKGA E V ++C + + + ++ T+ +
Sbjct: 455 SSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTT------YQSKGQTLTLTQQQRD 508
Query: 659 ALAHKTLKMGNLS-EVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVM 717
+ +MG+ V LA +LTFLGL+ + + + K + L + + M
Sbjct: 509 VYQQEKARMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKM 568
Query: 718 ITGDNLQTAITVA-------KNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGP 770
ITGD+ +TA+ +A K S+ + G ++ ++ + + VP +
Sbjct: 569 ITGDSQETAVAIASRLGLYSKTSQSV-SGEEIDAMDVQQLSQIVPKVAVF---------- 617
Query: 771 GKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQ 830
Y+ +H ++ + NG+V
Sbjct: 618 -------------------------------YRASPRHKMKIIKSLQKNGSV-------- 638
Query: 831 KSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASV---ASPFTSKTTNIQC 887
V M GDG ND ALKAA G+++ + V A+ + Q
Sbjct: 639 --------------VAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQT 684
Query: 888 VPHLIREGRAAL--VSSFGVFKYLTMYGIIQFISALLL 923
+ I EG+ + +F F+ T + IS L
Sbjct: 685 IMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
sapiens]
Length = 919
Score = 114 bits (286), Expect = 4e-25
Identities = 177/818 (21%), Positives = 311/818 (38%), Gaps = 162/818 (19%)
Query: 149 QKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEV-EIQPIWKLLVKQVLNPF 207
+K L S S + GL E RR G N ++ E +P+WK + Q NP
Sbjct: 24 KKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPL 83
Query: 208 YVF--QAFTLTLWLSQGYIEYSVAIIILTVISIV-LSVYDLRQQSVKLHNLV--EDHNKV 262
+ + +++ + Q S+ + IL V+++ + Y + +L LV E H
Sbjct: 84 IMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--- 140
Query: 263 QVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAVLIDG-SCVVNEGMLTGESIPVT 321
V++ LE +R LVPGD + L +P D L + ++E LTGE+ P +
Sbjct: 141 ----CVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCS 196
Query: 322 KTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLV 381
K PQ P + R ++ F GT V G + VV+ TG N+ G++
Sbjct: 197 KVTAPQ-----PAATNGDLASRSNIAFMGTLV------RCGKAKGVVIGTGENSEFGEVF 245
Query: 382 RSILY------PRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMAL 435
+ + P + L F F G++G +G + G + T+++
Sbjct: 246 KMMQAEEAPKTPLQKSMDLLGKQLSFYSF----GIIGIIMLVGWLL--GKDILEMFTISV 299
Query: 436 ILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDG 495
L +P LP +T+ R+ KK+ + G N++C DKTGTLT++
Sbjct: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
Query: 496 LDLWGTVPTADNCFQE---------AHSFASGQAV------PWSPLCAAMASCHSLILLN 540
+ + + T+D E G V S + A C+ ++ N
Sbjct: 360 MTV-THIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRN 418
Query: 541 GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPF 600
T+ G P + G ++ +K G + + I ++PF
Sbjct: 419 NTLMGKPTE---------------------GALIALAMKMGLDGLQ---QDYIRKAEYPF 454
Query: 601 SSSLQRMSV--IAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVI 658
SS + M+V + + + +MKGA E V ++C + + + ++ T+ +
Sbjct: 455 SSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTT------YQSKGQTLTLTQQQRD 508
Query: 659 ALAHKTLKMGNLS-EVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVM 717
+ +MG+ V LA +LTFLGL+ + + + K + L + + M
Sbjct: 509 VYQQEKARMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKM 568
Query: 718 ITGDNLQTAITVA-------KNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGP 770
ITGD+ +TA+ +A K S+ + G ++ ++ + + VP +
Sbjct: 569 ITGDSQETAVAIASRLGLYSKTSQSV-SGEEIDAMDVQQLSQIVPKVAVF---------- 617
Query: 771 GKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQ 830
Y+ +H ++ + NG+V
Sbjct: 618 -------------------------------YRASPRHKMKIIKSLQKNGSV-------- 638
Query: 831 KSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASV---ASPFTSKTTNIQC 887
V M GDG ND ALKAA G+++ + V A+ + Q
Sbjct: 639 --------------VAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQT 684
Query: 888 VPHLIREGRAAL--VSSFGVFKYLTMYGIIQFISALLL 923
+ I EG+ + +F F+ T + IS L
Sbjct: 685 IMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATL 722
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
sapiens]
Length = 1023
Score = 113 bits (283), Expect = 1e-24
Identities = 162/781 (20%), Positives = 298/781 (38%), Gaps = 133/781 (17%)
Query: 143 DLEKRFQKVGLLEDSNSCSDIHQTFGL----GLTSEEQEVRRLVCGPNAIEVE-IQPIWK 197
D+++ ++V + + S ++H+ +G GLTS GPNA+ P W
Sbjct: 31 DMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWI 90
Query: 198 LLVKQVLNPFYVFQAFTLTLWLSQ--GYIEYSVAI--------------IILTVISIVLS 241
+Q+ F F++ LW+ ++ YS+ ++L+ + I+
Sbjct: 91 KFCRQL------FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITG 144
Query: 242 VYDLRQQSVKLHNLVEDHNKV-QVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAV 300
+ Q++ + N V Q +++++ + + +V GD++ + G +P D
Sbjct: 145 CFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLR 204
Query: 301 LIDGS-CVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPS 359
+I + C V+ LTGES P T++P EN + +++ F T ++
Sbjct: 205 IISANGCKVDNSSLTGESEPQTRSPDFTNENPLE---------TRNIAFFSTNCVE---- 251
Query: 360 GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGV---MGFFYA 416
G R +V+ TG T G + + ++ FI + + V + FF
Sbjct: 252 --GTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFIL 309
Query: 417 LGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINM 476
+ Y + + V + ++ VP L A +T+ KR+ +K + + +
Sbjct: 310 SLILEYTWL---EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVET 366
Query: 477 CGQINLVCFDKTGTLTEDGL---DLW--GTVPTADNCFQEAHSFASGQAVPWSPLCAAMA 531
G + +C DKTGTLT++ + +W + AD ++ + W L
Sbjct: 367 LGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAG 426
Query: 532 SCH---------SLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGP 582
C+ +L +L + GD + + + CI C
Sbjct: 427 LCNRAVFQANQENLPILKRAVAGDASESALLK--------CIELCC-------------- 464
Query: 583 KASKSPVEAIITLCQFPFSSSLQRMSVIAQ--LAGENHFHVYMKGAPEMVARFCRS---- 636
+ K E + + PF+S+ + I + E + MKGAPE + C S
Sbjct: 465 GSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLH 524
Query: 637 -------ETVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEVEHLAREKVE---SELT 686
E + F G RV+ H L E + V L
Sbjct: 525 GKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLC 584
Query: 687 FLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVE 746
F+GL+ M + + + + A I+ +M+TGD+ TA +AK +I G++ +
Sbjct: 585 FVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV--- 641
Query: 747 ADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIF 806
E + A + + +Q K +H + M+ + I
Sbjct: 642 -----EDIAARL--NIPVSQVNPRDAKACVVHGSDLKD------------MTSEQLDDIL 682
Query: 807 QHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGIS 866
++ + VFAR SP QK ++E Q+ V + GDG ND ALK A G++
Sbjct: 683 KYHTEI---------VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVA 733
Query: 867 L 867
+
Sbjct: 734 M 734
>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
Length = 1023
Score = 113 bits (283), Expect = 1e-24
Identities = 162/781 (20%), Positives = 298/781 (38%), Gaps = 133/781 (17%)
Query: 143 DLEKRFQKVGLLEDSNSCSDIHQTFGL----GLTSEEQEVRRLVCGPNAIEVE-IQPIWK 197
D+++ ++V + + S ++H+ +G GLTS GPNA+ P W
Sbjct: 31 DMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWI 90
Query: 198 LLVKQVLNPFYVFQAFTLTLWLSQ--GYIEYSVAI--------------IILTVISIVLS 241
+Q+ F F++ LW+ ++ YS+ ++L+ + I+
Sbjct: 91 KFCRQL------FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITG 144
Query: 242 VYDLRQQSVKLHNLVEDHNKV-QVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAV 300
+ Q++ + N V Q +++++ + + +V GD++ + G +P D
Sbjct: 145 CFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLR 204
Query: 301 LIDGS-CVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPS 359
+I + C V+ LTGES P T++P EN + +++ F T ++
Sbjct: 205 IISANGCKVDNSSLTGESEPQTRSPDFTNENPLE---------TRNIAFFSTNCVE---- 251
Query: 360 GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGV---MGFFYA 416
G R +V+ TG T G + + ++ FI + + V + FF
Sbjct: 252 --GTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFIL 309
Query: 417 LGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINM 476
+ Y + + V + ++ VP L A +T+ KR+ +K + + +
Sbjct: 310 SLILEYTWL---EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVET 366
Query: 477 CGQINLVCFDKTGTLTEDGL---DLW--GTVPTADNCFQEAHSFASGQAVPWSPLCAAMA 531
G + +C DKTGTLT++ + +W + AD ++ + W L
Sbjct: 367 LGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAG 426
Query: 532 SCH---------SLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGP 582
C+ +L +L + GD + + + CI C
Sbjct: 427 LCNRAVFQANQENLPILKRAVAGDASESALLK--------CIELCC-------------- 464
Query: 583 KASKSPVEAIITLCQFPFSSSLQRMSVIAQ--LAGENHFHVYMKGAPEMVARFCRS---- 636
+ K E + + PF+S+ + I + E + MKGAPE + C S
Sbjct: 465 GSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLH 524
Query: 637 -------ETVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEVEHLAREKVE---SELT 686
E + F G RV+ H L E + V L
Sbjct: 525 GKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLC 584
Query: 687 FLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVE 746
F+GL+ M + + + + A I+ +M+TGD+ TA +AK +I G++ +
Sbjct: 585 FVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV--- 641
Query: 747 ADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIF 806
E + A + + +Q K +H + M+ + I
Sbjct: 642 -----EDIAARL--NIPVSQVNPRDAKACVVHGSDLKD------------MTSEQLDDIL 682
Query: 807 QHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGIS 866
++ + VFAR SP QK ++E Q+ V + GDG ND ALK A G++
Sbjct: 683 KYHTEI---------VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVA 733
Query: 867 L 867
+
Sbjct: 734 M 734
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
sapiens]
Length = 992
Score = 111 bits (277), Expect = 5e-24
Identities = 161/775 (20%), Positives = 294/775 (37%), Gaps = 133/775 (17%)
Query: 149 QKVGLLEDSNSCSDIHQTFGL----GLTSEEQEVRRLVCGPNAIEVE-IQPIWKLLVKQV 203
++V + + S ++H+ +G GLTS GPNA+ P W +Q+
Sbjct: 6 KEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL 65
Query: 204 LNPFYVFQAFTLTLWLSQ--GYIEYSVAI--------------IILTVISIVLSVYDLRQ 247
F F++ LW+ ++ YS+ ++L+ + I+ + Q
Sbjct: 66 ------FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQ 119
Query: 248 QSVKLHNLVEDHNKV-QVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAVLIDGS- 305
++ + N V Q +++++ + + +V GD++ + G +P D +I +
Sbjct: 120 EAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANG 179
Query: 306 CVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVR 365
C V+ LTGES P T++P EN + +++ F T ++ G R
Sbjct: 180 CKVDNSSLTGESEPQTRSPDFTNENPLE---------TRNIAFFSTNCVE------GTAR 224
Query: 366 AVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGV---MGFFYALGVYMY 422
+V+ TG T G + + ++ FI + + V + FF + Y
Sbjct: 225 GIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEY 284
Query: 423 HGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINL 482
+ + V + ++ VP L A +T+ KR+ +K + + + G +
Sbjct: 285 TWL---EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTST 341
Query: 483 VCFDKTGTLTEDGL---DLW--GTVPTADNCFQEAHSFASGQAVPWSPLCAAMASCH--- 534
+C DKTGTLT++ + +W + AD ++ + W L C+
Sbjct: 342 ICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAV 401
Query: 535 ------SLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSP 588
+L +L + GD + + + CI C + K
Sbjct: 402 FQANQENLPILKRAVAGDASESALLK--------CIELCC--------------GSVKEM 439
Query: 589 VEAIITLCQFPFSSSLQRMSVIAQ--LAGENHFHVYMKGAPEMVARFCRS---------- 636
E + + PF+S+ + I + E + MKGAPE + C S
Sbjct: 440 RERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPL 499
Query: 637 -ETVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEVEHLAREKVE---SELTFLGLLI 692
E + F G RV+ H L E + V L F+GL+
Sbjct: 500 DEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLIS 559
Query: 693 MENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEE 752
M + + + + A I+ +M+TGD+ TA +AK +I G++ + E
Sbjct: 560 MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV--------E 611
Query: 753 FVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSL 812
+ A + + +Q K +H + M+ + I ++ +
Sbjct: 612 DIAARL--NIPVSQVNPRDAKACVVHGSDLKD------------MTSEQLDDILKYHTEI 657
Query: 813 LPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISL 867
VFAR SP QK ++E Q+ V + GDG ND ALK A G+++
Sbjct: 658 ---------VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAM 703
>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
Length = 1013
Score = 111 bits (277), Expect = 5e-24
Identities = 160/773 (20%), Positives = 298/773 (38%), Gaps = 117/773 (15%)
Query: 143 DLEKRFQKVGLLEDSNSCSDIHQTFGL----GLTSEEQEVRRLVCGPNAIEVE-IQPIWK 197
DL+ ++V + E S ++ + + GLT + + GPNA+ P W
Sbjct: 21 DLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWV 80
Query: 198 LLVKQVLNPFYVFQAFTLTLWLSQ--GYIEYSVAI--------------IILTVISIVLS 241
+Q+ F F++ LW+ ++ Y + I+L + I+
Sbjct: 81 KFCRQL------FGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITG 134
Query: 242 VYDLRQQSVKLHNLVEDHNKV-QVTIIVKDKGLEELESRLLVPGDILILPGKFSLPCDAV 300
+ Q++ + N V Q +++++ ++ + +V GD++ + G +P D
Sbjct: 135 CFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLR 194
Query: 301 LIDG-SCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPS 359
+I C V+ LTGES P T++P +N + +++ F T ++
Sbjct: 195 IISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLE---------TRNITFFSTNCVE---- 241
Query: 360 GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGV-MGF-FYAL 417
G R VV+ TG T G + + + FI + + V +G F+ L
Sbjct: 242 --GTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFIL 299
Query: 418 GVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMC 477
+ + G + V + ++ VP L A +T+ KR+ +K + + +
Sbjct: 300 SLIL--GYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETL 357
Query: 478 GQINLVCFDKTGTLTEDGL---DLW--GTVPTADNCFQEAHSFASGQAVPWSPLCAAMAS 532
G + +C DKTGTLT++ + +W + AD ++ + + W L
Sbjct: 358 GSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGL 417
Query: 533 CHSLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPGPKASKSPVEAI 592
C+ + G D + + + E ++ + + +++ K
Sbjct: 418 CNRAVFKGGQ---DNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNK--------- 465
Query: 593 ITLCQFPFSSSLQRMSVIAQL--AGENHFHVYMKGAPEMVARFCRS-----------ETV 639
+ + PF+S+ + I + +N + + MKGAPE + C + E +
Sbjct: 466 -KVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEM 524
Query: 640 PKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEVEHLAREKVE---SELTFLGLLIMENR 696
+ F G RV+ H L + + V L F+GL+ M +
Sbjct: 525 KEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDP 584
Query: 697 LKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPA 756
+ + + A I+ +M+TGD+ TA +AK +I G++ VE +P
Sbjct: 585 PRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNET--VEDIAARLNIPV 642
Query: 757 SVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKI 816
S PR + +C K + + + +I
Sbjct: 643 S------------------------QVNPR-DAKACVIHGTDLKDFT------SEQIDEI 671
Query: 817 LVNGT--VFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISL 867
L N T VFAR SP QK ++E Q+ V + GDG ND ALK A G+++
Sbjct: 672 LQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAM 724
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 109 bits (272), Expect = 2e-23
Identities = 162/652 (24%), Positives = 278/652 (42%), Gaps = 60/652 (9%)
Query: 94 YLSTLKFPVSKKWEESLVADRHSVINQALIKPELKLRCMEVQKIRYVWNDLEK-RFQKVG 152
+L L F + ++L D +ALI + +L+ +E +K E + QK
Sbjct: 9 FLKKLGFSGGGRQYQALEKDEE----EALIDEQSELKAIEKEKKVTALPPKEACKCQKED 64
Query: 153 LLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVE-IQPIWKLLVKQVLNPFYVFQ 211
L C D+H GL+ RRL G N + +P+WK + Q NP +
Sbjct: 65 LARAF--CVDLHT----GLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLL 118
Query: 212 -AFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKV--QVTIIV 268
L L++ EY A+ I T + +V++V + Q + +E+ K+ +
Sbjct: 119 LGSALVSVLTK---EYEDAVSIATAVLVVVTVAFI--QEYRSEKSLEELTKMVPPECNCL 173
Query: 269 KDKGLEELESRLLVPGDILILPGKFSLPCDAVLIDGS-CVVNEGMLTGESIPVTKTPLPQ 327
++ L+ L +R LVPGD++ L +P D L + + +V+E TGE+ P +KT P
Sbjct: 174 REGKLQHLLARELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPL 233
Query: 328 MENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYP 387
T +L + ++F GT V + GQG VV+ TG ++ G++ + +
Sbjct: 234 ---TGGGDLTTLSN----IVFMGTLVQYGR--GQG----VVIGTGESSQFGEVFKMMQAE 280
Query: 388 RPLNFKLYS--DAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPV 445
L D + L G++G +G G T+ + L +P
Sbjct: 281 ETPKTPLQKSMDRLGKQLTLFSFGIIGLIMLIG--WSQGKQLLSMFTIGVSLAVAAIPEG 338
Query: 446 LPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTA 505
LP + + V R+ KK++ + G +++C DKTGTLT + + + V T+
Sbjct: 339 LPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLV-TS 397
Query: 506 DNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDCIV 565
D E SG + S + + G ++ A ++ ++
Sbjct: 398 DGLRAE----VSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVM 453
Query: 566 DSCKFGTSVSNIIKPGPKASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGENHFHVY-MK 624
G ++ +K K+ + I + PFSS + M+V L E+ +Y MK
Sbjct: 454 GQPTEGALMALAMKMDLSDIKN---SYIRKKEIPFSSEQKWMAVKCSLKTEDQEDIYFMK 510
Query: 625 GAPEMVARFC---RSETVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLS-EVEHLAREK 680
GA E V R+C + +P + RS+ +Q + +MG+L V LA
Sbjct: 511 GALEEVIRYCTMYNNGGIPLPLTPQQRSFCLQ---------EEKRMGSLGLRVLALASGP 561
Query: 681 VESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKN 732
LTFLGL+ + + + K ++ LSE+ + MITGD L+TA+ + +N
Sbjct: 562 ELGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRN 613
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 821 TVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASV---ASP 877
+VF R SP K +I+ Q+ V M GDG ND ALK+A GI++ + V A+
Sbjct: 645 SVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAAN 704
Query: 878 FTSKTTNIQCVPHLIREGRAAL--VSSFGVFKYLTMYGIIQFIS 919
+ + + + EG+ + +F F+ T + I+
Sbjct: 705 MILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLIT 748
>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
Length = 1035
Score = 108 bits (271), Expect = 2e-23
Identities = 150/673 (22%), Positives = 256/673 (38%), Gaps = 103/673 (15%)
Query: 227 SVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKV--QVTIIVKDKGLEELESRLLVPG 284
++A+I + V++ Y Q K N++ + Q +++D ++ + LV G
Sbjct: 144 AIALIAVVVVTGCFGYY----QEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVG 199
Query: 285 DILILPGKFSLPCDA-VLIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYR 343
D++ + G +P D +L C V+ LTGES P T++P E+ +
Sbjct: 200 DLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLE---------T 250
Query: 344 KHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIV 403
+++ F T ++ G V+ +V+ TG T G + + + F+
Sbjct: 251 RNIAFFSTMCLE------GTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVD 304
Query: 404 FLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKK 463
+A L ++ V M G + + ++ VP L A +T+ KRL
Sbjct: 305 IIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLAS 364
Query: 464 KKIFCISPQRINMCGQINLVCFDKTGTLTEDGL---DLW--GTVPTADNCFQEAHSFASG 518
K + + + G +++C DKTGTLT++ + LW + TAD ++
Sbjct: 365 KNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQ 424
Query: 519 QAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNII 578
+ W LC + C+ +G P+ ++ G A + G ++
Sbjct: 425 SSETWRALCRVLTLCNRAAFKSGQ-DAVPVPKRIVIGDASETALLKFSELTLGNAMGY-- 481
Query: 579 KPGPKASKSPVEAIITLCQFPFSSSLQRMSVIAQLAG--ENHFHVYMKGAPEMVARFCRS 636
+ +C+ PF+S+ + I L + + MKGAPE V C S
Sbjct: 482 ----------RDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSS 531
Query: 637 ETVP-KNFPQELR---------------SYTVQGFRVIALAHKTLKMGNLSEVEHLAREK 680
+ + P + + V GF + L K G +VE A
Sbjct: 532 ILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVE--AMNF 589
Query: 681 VESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGS 740
S L F GL+ M + + + + A IR +M+TGD+ TA +A + +I GS
Sbjct: 590 PSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGS 649
Query: 741 QVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGK 800
+ + E + A + R + +C M K
Sbjct: 650 ETV--------EDIAAR-------------------LRVPVDQVNRKDARACVINGMQLK 682
Query: 801 SYQVIFQHFNSLLPKILVNG------TVFARMSPGQKSSLIEEFQKLNYYVGMCGDGAND 854
P LV VFAR SP QK ++E Q+L V + GDG ND
Sbjct: 683 DMD----------PSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVND 732
Query: 855 CGALKAAHAGISL 867
ALK A G+++
Sbjct: 733 SPALKKADIGVAM 745
>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
[Homo sapiens]
Length = 1015
Score = 101 bits (251), Expect = 5e-21
Identities = 177/807 (21%), Positives = 298/807 (36%), Gaps = 171/807 (21%)
Query: 184 GPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQG------YIEYSVAIIILTVIS 237
G +E+ I+ LLV+ +L + +F L W +G ++E V ++IL V +
Sbjct: 46 GKTLLELVIEQFEDLLVRILLLAACI--SFVLA-WFEEGEETITAFVEPFVILLIL-VAN 101
Query: 238 IVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPGKFSLPC 297
++ V+ R + L E ++ K ++ ++++ +VPGDI+
Sbjct: 102 AIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIV---------- 151
Query: 298 DAVLIDGSCVVNEGMLTGESIPVTK--TPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQ 355
+ GES+ V K P+P ++ +K++LF GT +
Sbjct: 152 --------------EIAGESVSVIKHTDPVPDPR--------AVNQDKKNMLFSGTNIAA 189
Query: 356 VKPSGQGPVRAVVLQTGYNTAKG----DLVRSILYPRPLNFKL--YSDAFKFIVFLACLG 409
K G VV+ TG NT G ++V + PL KL + + ++ L C+
Sbjct: 190 GKAMG------VVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIA 243
Query: 410 V----MGFF--------YALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYA 457
V +G F + G Y + A+ L +P LPA +T
Sbjct: 244 VWIINIGHFNDPVHGGSWIRGAIYYFKI--------AVALAVAAIPEGLPAVITTCLALG 295
Query: 458 QKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTV----PTADNCFQEAH 513
+R+ KK S + G +++C DKTGTLT + + + D C
Sbjct: 296 TRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEF 355
Query: 514 SFASGQAVPWSPLCA--AMASCH------SLILLNGTIQGDPLDLKMFEGTAWKMED--- 562
+ P + +CH L + LD +G K+ +
Sbjct: 356 TITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATE 415
Query: 563 ----CIVDSCK-FGTSVSNIIK-PGPKASKSPVEAIITL-CQFPFSSSLQRMSVIA---Q 612
C+V+ F T + + K A S ++ ++ FS + MSV +
Sbjct: 416 TALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNK 475
Query: 613 LAGENHFHVYMKGAPEMVARFCR-----SETVPKNFPQELRSYTV--------QGFRVIA 659
+ + +++KGAPE V C S VP + + +V R +A
Sbjct: 476 PSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLA 535
Query: 660 LA--HKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVM 717
LA L+ + + K E+ LTF+G + M + + E +K +A IR +M
Sbjct: 536 LATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIM 595
Query: 718 ITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYM 777
ITGDN TA+ + + ++ I DE VT + +E
Sbjct: 596 ITGDNKGTAVAICR---------RIGIFGQDE-------DVTSKAFTGREF--------- 630
Query: 778 HTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEE 837
+ P + +C +N FAR+ P KS ++E
Sbjct: 631 ---DELNPSAQRDAC-------------------------LNARCFARVEPSHKSKIVEF 662
Query: 838 FQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTSKTTNIQCVPHLIREG 895
Q + M GDG ND ALK A GI++ A AS N + + EG
Sbjct: 663 LQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEG 722
Query: 896 RAALVSSFGVFKYLTMYGIIQFISALL 922
RA + +YL + + + L
Sbjct: 723 RAIYNNMKQFIRYLISSNVGEVVCIFL 749
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 91.3 bits (225), Expect = 5e-18
Identities = 147/635 (23%), Positives = 255/635 (40%), Gaps = 93/635 (14%)
Query: 170 GLTSEEQEVRRLVCGPNAIEVEI-QPIWKLLVKQ---VLNPFYVFQAFT--LTLWLSQG- 222
GL+ + R GPN + E + +W+L+++Q +L + A + W +G
Sbjct: 23 GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82
Query: 223 -----YIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELE 277
++E V ++IL V + ++ V+ R + L E ++ I KG++ +
Sbjct: 83 ETTTAFVEPLVIMLIL-VANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIR 141
Query: 278 SRLLVPGDILILPGKFSLPCDAVLIDGSCV---VNEGMLTGESIPVTK----TPLPQMEN 330
+R +VPGDI+ + +P D LI+ V++ +LTGES+ VTK P P+ N
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVN 201
Query: 331 TMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPL 390
+K++LF GT + K G V + TG +T G + + P
Sbjct: 202 ----------QDKKNMLFSGTNITSGKAVG------VAVATGLHTELGKIRSQMAAVEPE 245
Query: 391 NFKLYSDAFKF------IVFLACLGV----MGFFY--ALGVYMYHGVPPKDTVTMALILL 438
L +F + + C+ V +G F A G G + +AL +
Sbjct: 246 RTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAV- 304
Query: 439 TVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDL 498
+P LPA +T +R+ +K S + G +++C DKTGTLT + + +
Sbjct: 305 -AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV 363
Query: 499 WGTVPTAD----NCFQEAHSFASGQAVPWSPL--------CAAMASCHSLILLNGTIQGD 546
A+ +C + + P + C L +
Sbjct: 364 CRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDS 423
Query: 547 PLDLKMFEGTAWKMED-------CIVDSCK-FGTSVSNIIKPGPKASKSPVEAIITLCQF 598
LD +G K+ + C+V+ F T + + + + + V + +F
Sbjct: 424 ALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEF 483
Query: 599 --PFSSSLQRMSVIA-----QLAGENHFHVYMKGAPEMVARFCRSETV--------PKNF 643
FS + MSV G+ +++KGAPE V C S V P +
Sbjct: 484 TLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCSSVRVGSRTAPLTPTSR 542
Query: 644 PQELRSYTVQG-----FRVIALAHKTLKMGNLS-EVEHLAR-EKVESELTFLGLLIMENR 696
Q L G R +ALA + E++ ++ + E++LTF+G + M +
Sbjct: 543 EQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDP 602
Query: 697 LKKETKLVLKELSEARIRTVMITGDNLQTAITVAK 731
+ E + +A IR VMITGDN TA+ + +
Sbjct: 603 PRPEVAACITRCYQAGIRVVMITGDNKGTAVAICR 637
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 823 FARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTS 880
FAR+ P KS ++E Q N M GDG ND ALK A GI++ A A+
Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735
Query: 881 KTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALL 922
N + + EGRA + +YL + + + L
Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 91.3 bits (225), Expect = 5e-18
Identities = 147/635 (23%), Positives = 255/635 (40%), Gaps = 93/635 (14%)
Query: 170 GLTSEEQEVRRLVCGPNAIEVEI-QPIWKLLVKQ---VLNPFYVFQAFT--LTLWLSQG- 222
GL+ + R GPN + E + +W+L+++Q +L + A + W +G
Sbjct: 23 GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82
Query: 223 -----YIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELE 277
++E V ++IL V + ++ V+ R + L E ++ I KG++ +
Sbjct: 83 ETTTAFVEPLVIMLIL-VANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIR 141
Query: 278 SRLLVPGDILILPGKFSLPCDAVLIDGSCV---VNEGMLTGESIPVTK----TPLPQMEN 330
+R +VPGDI+ + +P D LI+ V++ +LTGES+ VTK P P+ N
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVN 201
Query: 331 TMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPL 390
+K++LF GT + K G V + TG +T G + + P
Sbjct: 202 ----------QDKKNMLFSGTNITSGKAVG------VAVATGLHTELGKIRSQMAAVEPE 245
Query: 391 NFKLYSDAFKF------IVFLACLGV----MGFFY--ALGVYMYHGVPPKDTVTMALILL 438
L +F + + C+ V +G F A G G + +AL +
Sbjct: 246 RTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAV- 304
Query: 439 TVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDL 498
+P LPA +T +R+ +K S + G +++C DKTGTLT + + +
Sbjct: 305 -AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV 363
Query: 499 WGTVPTAD----NCFQEAHSFASGQAVPWSPL--------CAAMASCHSLILLNGTIQGD 546
A+ +C + + P + C L +
Sbjct: 364 CRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDS 423
Query: 547 PLDLKMFEGTAWKMED-------CIVDSCK-FGTSVSNIIKPGPKASKSPVEAIITLCQF 598
LD +G K+ + C+V+ F T + + + + + V + +F
Sbjct: 424 ALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEF 483
Query: 599 --PFSSSLQRMSVIA-----QLAGENHFHVYMKGAPEMVARFCRSETV--------PKNF 643
FS + MSV G+ +++KGAPE V C S V P +
Sbjct: 484 TLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCSSVRVGSRTAPLTPTSR 542
Query: 644 PQELRSYTVQG-----FRVIALAHKTLKMGNLS-EVEHLAR-EKVESELTFLGLLIMENR 696
Q L G R +ALA + E++ ++ + E++LTF+G + M +
Sbjct: 543 EQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDP 602
Query: 697 LKKETKLVLKELSEARIRTVMITGDNLQTAITVAK 731
+ E + +A IR VMITGDN TA+ + +
Sbjct: 603 PRPEVAACITRCYQAGIRVVMITGDNKGTAVAICR 637
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 823 FARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTS 880
FAR+ P KS ++E Q N M GDG ND ALK A GI++ A A+
Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735
Query: 881 KTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALL 922
N + + EGRA + +YL + + + L
Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 91.3 bits (225), Expect = 5e-18
Identities = 147/635 (23%), Positives = 255/635 (40%), Gaps = 93/635 (14%)
Query: 170 GLTSEEQEVRRLVCGPNAIEVEI-QPIWKLLVKQ---VLNPFYVFQAFT--LTLWLSQG- 222
GL+ + R GPN + E + +W+L+++Q +L + A + W +G
Sbjct: 23 GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82
Query: 223 -----YIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELE 277
++E V ++IL V + ++ V+ R + L E ++ I KG++ +
Sbjct: 83 ETTTAFVEPLVIMLIL-VANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIR 141
Query: 278 SRLLVPGDILILPGKFSLPCDAVLIDGSCV---VNEGMLTGESIPVTK----TPLPQMEN 330
+R +VPGDI+ + +P D LI+ V++ +LTGES+ VTK P P+ N
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVN 201
Query: 331 TMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPL 390
+K++LF GT + K G V + TG +T G + + P
Sbjct: 202 ----------QDKKNMLFSGTNITSGKAVG------VAVATGLHTELGKIRSQMAAVEPE 245
Query: 391 NFKLYSDAFKF------IVFLACLGV----MGFFY--ALGVYMYHGVPPKDTVTMALILL 438
L +F + + C+ V +G F A G G + +AL +
Sbjct: 246 RTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAV- 304
Query: 439 TVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDL 498
+P LPA +T +R+ +K S + G +++C DKTGTLT + + +
Sbjct: 305 -AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV 363
Query: 499 WGTVPTAD----NCFQEAHSFASGQAVPWSPL--------CAAMASCHSLILLNGTIQGD 546
A+ +C + + P + C L +
Sbjct: 364 CRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDS 423
Query: 547 PLDLKMFEGTAWKMED-------CIVDSCK-FGTSVSNIIKPGPKASKSPVEAIITLCQF 598
LD +G K+ + C+V+ F T + + + + + V + +F
Sbjct: 424 ALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEF 483
Query: 599 --PFSSSLQRMSVIA-----QLAGENHFHVYMKGAPEMVARFCRSETV--------PKNF 643
FS + MSV G+ +++KGAPE V C S V P +
Sbjct: 484 TLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCSSVRVGSRTAPLTPTSR 542
Query: 644 PQELRSYTVQG-----FRVIALAHKTLKMGNLS-EVEHLAR-EKVESELTFLGLLIMENR 696
Q L G R +ALA + E++ ++ + E++LTF+G + M +
Sbjct: 543 EQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDP 602
Query: 697 LKKETKLVLKELSEARIRTVMITGDNLQTAITVAK 731
+ E + +A IR VMITGDN TA+ + +
Sbjct: 603 PRPEVAACITRCYQAGIRVVMITGDNKGTAVAICR 637
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 823 FARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTS 880
FAR+ P KS ++E Q N M GDG ND ALK A GI++ A A+
Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735
Query: 881 KTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALL 922
N + + EGRA + +YL + + + L
Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 91.3 bits (225), Expect = 5e-18
Identities = 147/635 (23%), Positives = 255/635 (40%), Gaps = 93/635 (14%)
Query: 170 GLTSEEQEVRRLVCGPNAIEVEI-QPIWKLLVKQ---VLNPFYVFQAFT--LTLWLSQG- 222
GL+ + R GPN + E + +W+L+++Q +L + A + W +G
Sbjct: 23 GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82
Query: 223 -----YIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELE 277
++E V ++IL V + ++ V+ R + L E ++ I KG++ +
Sbjct: 83 ETTTAFVEPLVIMLIL-VANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIR 141
Query: 278 SRLLVPGDILILPGKFSLPCDAVLIDGSCV---VNEGMLTGESIPVTK----TPLPQMEN 330
+R +VPGDI+ + +P D LI+ V++ +LTGES+ VTK P P+ N
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVN 201
Query: 331 TMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPL 390
+K++LF GT + K G V + TG +T G + + P
Sbjct: 202 ----------QDKKNMLFSGTNITSGKAVG------VAVATGLHTELGKIRSQMAAVEPE 245
Query: 391 NFKLYSDAFKF------IVFLACLGV----MGFFY--ALGVYMYHGVPPKDTVTMALILL 438
L +F + + C+ V +G F A G G + +AL +
Sbjct: 246 RTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAV- 304
Query: 439 TVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDL 498
+P LPA +T +R+ +K S + G +++C DKTGTLT + + +
Sbjct: 305 -AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV 363
Query: 499 WGTVPTAD----NCFQEAHSFASGQAVPWSPL--------CAAMASCHSLILLNGTIQGD 546
A+ +C + + P + C L +
Sbjct: 364 CRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDS 423
Query: 547 PLDLKMFEGTAWKMED-------CIVDSCK-FGTSVSNIIKPGPKASKSPVEAIITLCQF 598
LD +G K+ + C+V+ F T + + + + + V + +F
Sbjct: 424 ALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEF 483
Query: 599 --PFSSSLQRMSVIA-----QLAGENHFHVYMKGAPEMVARFCRSETV--------PKNF 643
FS + MSV G+ +++KGAPE V C S V P +
Sbjct: 484 TLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCSSVRVGSRTAPLTPTSR 542
Query: 644 PQELRSYTVQG-----FRVIALAHKTLKMGNLS-EVEHLAR-EKVESELTFLGLLIMENR 696
Q L G R +ALA + E++ ++ + E++LTF+G + M +
Sbjct: 543 EQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDP 602
Query: 697 LKKETKLVLKELSEARIRTVMITGDNLQTAITVAK 731
+ E + +A IR VMITGDN TA+ + +
Sbjct: 603 PRPEVAACITRCYQAGIRVVMITGDNKGTAVAICR 637
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 823 FARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTS 880
FAR+ P KS ++E Q N M GDG ND ALK A GI++ A A+
Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735
Query: 881 KTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALL 922
N + + EGRA + +YL + + + L
Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 91.3 bits (225), Expect = 5e-18
Identities = 147/635 (23%), Positives = 255/635 (40%), Gaps = 93/635 (14%)
Query: 170 GLTSEEQEVRRLVCGPNAIEVEI-QPIWKLLVKQ---VLNPFYVFQAFT--LTLWLSQG- 222
GL+ + R GPN + E + +W+L+++Q +L + A + W +G
Sbjct: 23 GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82
Query: 223 -----YIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELE 277
++E V ++IL V + ++ V+ R + L E ++ I KG++ +
Sbjct: 83 ETTTAFVEPLVIMLIL-VANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIR 141
Query: 278 SRLLVPGDILILPGKFSLPCDAVLIDGSCV---VNEGMLTGESIPVTK----TPLPQMEN 330
+R +VPGDI+ + +P D LI+ V++ +LTGES+ VTK P P+ N
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVN 201
Query: 331 TMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPL 390
+K++LF GT + K G V + TG +T G + + P
Sbjct: 202 ----------QDKKNMLFSGTNITSGKAVG------VAVATGLHTELGKIRSQMAAVEPE 245
Query: 391 NFKLYSDAFKF------IVFLACLGV----MGFFY--ALGVYMYHGVPPKDTVTMALILL 438
L +F + + C+ V +G F A G G + +AL +
Sbjct: 246 RTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAV- 304
Query: 439 TVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDL 498
+P LPA +T +R+ +K S + G +++C DKTGTLT + + +
Sbjct: 305 -AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV 363
Query: 499 WGTVPTAD----NCFQEAHSFASGQAVPWSPL--------CAAMASCHSLILLNGTIQGD 546
A+ +C + + P + C L +
Sbjct: 364 CRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDS 423
Query: 547 PLDLKMFEGTAWKMED-------CIVDSCK-FGTSVSNIIKPGPKASKSPVEAIITLCQF 598
LD +G K+ + C+V+ F T + + + + + V + +F
Sbjct: 424 ALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEF 483
Query: 599 --PFSSSLQRMSVIA-----QLAGENHFHVYMKGAPEMVARFCRSETV--------PKNF 643
FS + MSV G+ +++KGAPE V C S V P +
Sbjct: 484 TLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCSSVRVGSRTAPLTPTSR 542
Query: 644 PQELRSYTVQG-----FRVIALAHKTLKMGNLS-EVEHLAR-EKVESELTFLGLLIMENR 696
Q L G R +ALA + E++ ++ + E++LTF+G + M +
Sbjct: 543 EQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDP 602
Query: 697 LKKETKLVLKELSEARIRTVMITGDNLQTAITVAK 731
+ E + +A IR VMITGDN TA+ + +
Sbjct: 603 PRPEVAACITRCYQAGIRVVMITGDNKGTAVAICR 637
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 823 FARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTS 880
FAR+ P KS ++E Q N M GDG ND ALK A GI++ A A+
Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735
Query: 881 KTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALL 922
N + + EGRA + +YL + + + L
Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 91.3 bits (225), Expect = 5e-18
Identities = 147/635 (23%), Positives = 255/635 (40%), Gaps = 93/635 (14%)
Query: 170 GLTSEEQEVRRLVCGPNAIEVEI-QPIWKLLVKQ---VLNPFYVFQAFT--LTLWLSQG- 222
GL+ + R GPN + E + +W+L+++Q +L + A + W +G
Sbjct: 23 GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82
Query: 223 -----YIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELE 277
++E V ++IL V + ++ V+ R + L E ++ I KG++ +
Sbjct: 83 ETTTAFVEPLVIMLIL-VANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIR 141
Query: 278 SRLLVPGDILILPGKFSLPCDAVLIDGSCV---VNEGMLTGESIPVTK----TPLPQMEN 330
+R +VPGDI+ + +P D LI+ V++ +LTGES+ VTK P P+ N
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVN 201
Query: 331 TMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPL 390
+K++LF GT + K G V + TG +T G + + P
Sbjct: 202 ----------QDKKNMLFSGTNITSGKAVG------VAVATGLHTELGKIRSQMAAVEPE 245
Query: 391 NFKLYSDAFKF------IVFLACLGV----MGFFY--ALGVYMYHGVPPKDTVTMALILL 438
L +F + + C+ V +G F A G G + +AL +
Sbjct: 246 RTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAV- 304
Query: 439 TVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDL 498
+P LPA +T +R+ +K S + G +++C DKTGTLT + + +
Sbjct: 305 -AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV 363
Query: 499 WGTVPTAD----NCFQEAHSFASGQAVPWSPL--------CAAMASCHSLILLNGTIQGD 546
A+ +C + + P + C L +
Sbjct: 364 CRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDS 423
Query: 547 PLDLKMFEGTAWKMED-------CIVDSCK-FGTSVSNIIKPGPKASKSPVEAIITLCQF 598
LD +G K+ + C+V+ F T + + + + + V + +F
Sbjct: 424 ALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEF 483
Query: 599 --PFSSSLQRMSVIA-----QLAGENHFHVYMKGAPEMVARFCRSETV--------PKNF 643
FS + MSV G+ +++KGAPE V C S V P +
Sbjct: 484 TLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCSSVRVGSRTAPLTPTSR 542
Query: 644 PQELRSYTVQG-----FRVIALAHKTLKMGNLS-EVEHLAR-EKVESELTFLGLLIMENR 696
Q L G R +ALA + E++ ++ + E++LTF+G + M +
Sbjct: 543 EQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDP 602
Query: 697 LKKETKLVLKELSEARIRTVMITGDNLQTAITVAK 731
+ E + +A IR VMITGDN TA+ + +
Sbjct: 603 PRPEVAACITRCYQAGIRVVMITGDNKGTAVAICR 637
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 823 FARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTS 880
FAR+ P KS ++E Q N M GDG ND ALK A GI++ A A+
Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735
Query: 881 KTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALL 922
N + + EGRA + +YL + + + L
Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
sapiens]
Length = 1052
Score = 91.3 bits (225), Expect = 5e-18
Identities = 147/635 (23%), Positives = 255/635 (40%), Gaps = 93/635 (14%)
Query: 170 GLTSEEQEVRRLVCGPNAIEVEI-QPIWKLLVKQ---VLNPFYVFQAFT--LTLWLSQG- 222
GL+ + R GPN + E + +W+L+++Q +L + A + W +G
Sbjct: 23 GLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGE 82
Query: 223 -----YIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELE 277
++E V ++IL V + ++ V+ R + L E ++ I KG++ +
Sbjct: 83 ETTTAFVEPLVIMLIL-VANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIR 141
Query: 278 SRLLVPGDILILPGKFSLPCDAVLIDGSCV---VNEGMLTGESIPVTK----TPLPQMEN 330
+R +VPGDI+ + +P D LI+ V++ +LTGES+ VTK P P+ N
Sbjct: 142 ARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVN 201
Query: 331 TMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPL 390
+K++LF GT + K G V + TG +T G + + P
Sbjct: 202 ----------QDKKNMLFSGTNITSGKAVG------VAVATGLHTELGKIRSQMAAVEPE 245
Query: 391 NFKLYSDAFKF------IVFLACLGV----MGFFY--ALGVYMYHGVPPKDTVTMALILL 438
L +F + + C+ V +G F A G G + +AL +
Sbjct: 246 RTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAV- 304
Query: 439 TVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDL 498
+P LPA +T +R+ +K S + G +++C DKTGTLT + + +
Sbjct: 305 -AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV 363
Query: 499 WGTVPTAD----NCFQEAHSFASGQAVPWSPL--------CAAMASCHSLILLNGTIQGD 546
A+ +C + + P + C L +
Sbjct: 364 CRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDS 423
Query: 547 PLDLKMFEGTAWKMED-------CIVDSCK-FGTSVSNIIKPGPKASKSPVEAIITLCQF 598
LD +G K+ + C+V+ F T + + + + + V + +F
Sbjct: 424 ALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEF 483
Query: 599 --PFSSSLQRMSVIA-----QLAGENHFHVYMKGAPEMVARFCRSETV--------PKNF 643
FS + MSV G+ +++KGAPE V C S V P +
Sbjct: 484 TLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCSSVRVGSRTAPLTPTSR 542
Query: 644 PQELRSYTVQG-----FRVIALAHKTLKMGNLS-EVEHLAR-EKVESELTFLGLLIMENR 696
Q L G R +ALA + E++ ++ + E++LTF+G + M +
Sbjct: 543 EQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDP 602
Query: 697 LKKETKLVLKELSEARIRTVMITGDNLQTAITVAK 731
+ E + +A IR VMITGDN TA+ + +
Sbjct: 603 PRPEVAACITRCYQAGIRVVMITGDNKGTAVAICR 637
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 823 FARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSE--QEASVASPFTS 880
FAR+ P KS ++E Q N M GDG ND ALK A GI++ A A+
Sbjct: 676 FARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVL 735
Query: 881 KTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALL 922
N + + EGRA + +YL + + + L
Sbjct: 736 SDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,574,609
Number of Sequences: 37866
Number of extensions: 2095294
Number of successful extensions: 4714
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 4381
Number of HSP's gapped (non-prelim): 192
length of query: 1218
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1104
effective length of database: 13,930,794
effective search space: 15379596576
effective search space used: 15379596576
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.