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Search of human proteins with 62988359
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo
sapiens]
(600 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens] 1231 0.0
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 953 0.0
gi|30089954 H326 [Homo sapiens] 795 0.0
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens] 127 2e-29
gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens] 127 2e-29
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 107 2e-23
gi|55741849 WD repeat domain 22 [Homo sapiens] 73 9e-13
gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ... 64 3e-10
gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s... 64 3e-10
gi|16554629 WD repeat domain 5 [Homo sapiens] 63 9e-10
gi|16554627 WD repeat domain 5 [Homo sapiens] 63 9e-10
gi|147904340 WD repeat domain 82 [Homo sapiens] 62 2e-09
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens] 62 2e-09
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens] 62 2e-09
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 59 1e-08
gi|23199987 WD repeat domain 5B [Homo sapiens] 57 4e-08
gi|17975763 myelin transcription factor 1 [Homo sapiens] 54 3e-07
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 53 9e-07
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 52 2e-06
gi|8922301 WD repeat domain 70 [Homo sapiens] 49 1e-05
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 48 2e-05
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 47 7e-05
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 46 9e-05
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 46 9e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 46 9e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 46 9e-05
gi|113865883 WD repeat domain 38 [Homo sapiens] 46 1e-04
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 44 3e-04
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 44 3e-04
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 44 3e-04
>gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens]
Length = 600
Score = 1231 bits (3185), Expect = 0.0
Identities = 600/600 (100%), Positives = 600/600 (100%)
Query: 1 MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFL 60
MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFL
Sbjct: 1 MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFL 60
Query: 61 NDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGEEEEQPRMC 120
NDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGEEEEQPRMC
Sbjct: 61 NDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGEEEEQPRMC 120
Query: 121 PRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEACGAR 180
PRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEACGAR
Sbjct: 121 PRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEACGAR 180
Query: 181 TFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDI 240
TFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDI
Sbjct: 181 TFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDI 240
Query: 241 NVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPY 300
NVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPY
Sbjct: 241 NVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPY 300
Query: 301 KFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVR 360
KFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVR
Sbjct: 301 KFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVR 360
Query: 361 IYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSS 420
IYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSS
Sbjct: 361 IYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSS 420
Query: 421 LSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDR 480
LSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDR
Sbjct: 421 LSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDR 480
Query: 481 GDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYT 540
GDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYT
Sbjct: 481 GDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYT 540
Query: 541 DSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQCIPS 600
DSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQCIPS
Sbjct: 541 DSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQCIPS 600
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 953 bits (2463), Expect = 0.0
Identities = 482/632 (76%), Positives = 524/632 (82%), Gaps = 33/632 (5%)
Query: 1 MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPS---TGDGGDTRDG 57
MSHQEGST GLPDL TESLFSSPEEQSG A T ASSDI++A +E S TGDG D+RDG
Sbjct: 1 MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60
Query: 58 GFLNDASTENQNTDSESSSEDVELESM---------GEGLFGYPLVGEE-TEREEEEEEM 107
GF NDASTEN+++D ES+SED+ELES+ GE LF YPLVGEE TEREEE+EE+
Sbjct: 61 GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
Query: 108 EEEG-------------------EEEEQPRMCPRCGGTNHDQCLLDEDQALEEWISSETS 148
+EEG EEEEQPR P+ G NH+Q L+EDQALEEW+SSETS
Sbjct: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS 180
Query: 149 ALPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRG 208
ALPR RWQV+TAL QRQLGS RFVYEACGAR FVQRFRLQY L H G V+T+HFNQRG
Sbjct: 181 ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG 240
Query: 209 TRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVA 268
TRLASSGDDL+VIVWDWVRQ+PVLNFESGH NV QAKF PNCGDSTLAMC DGQVRVA
Sbjct: 241 TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA 300
Query: 269 ELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 328
ELINASY NTK VA+HRGPAH+LALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT
Sbjct: 301 ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 360
Query: 329 RENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCD 388
RENDKKVGLYTI++NPAN YQFAVGG DQFVRIYDQR+IDKKENNGVLKKFTPHHLV CD
Sbjct: 361 RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD 420
Query: 389 FPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGP 448
FPTNITCVVYSHDGTELLASYND+DIYLFNSS SDGAQY KR+KGHRNN T+K VNFYGP
Sbjct: 421 FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP 480
Query: 449 RSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIW 508
RSEFVVSGSDCGH+FFWEKSS QIIQF++G R +NCLEPHPYLPVLA SGLD V+IW
Sbjct: 481 RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW 540
Query: 509 TPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVRHLLQRAHQPGWRDHG 568
TPTAK ATELTGLK VIKKNK ERDED+L++ FD ML F +RH+ QR WR
Sbjct: 541 TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE 600
Query: 569 AEFPDEEELDESSSTSDTSEEEGQDRVQCIPS 600
AEFPDEE DESSSTS+TSEEE QDRVQC+PS
Sbjct: 601 AEFPDEES-DESSSTSETSEEEVQDRVQCMPS 631
>gi|30089954 H326 [Homo sapiens]
Length = 597
Score = 795 bits (2052), Expect = 0.0
Identities = 410/604 (67%), Positives = 474/604 (78%), Gaps = 11/604 (1%)
Query: 1 MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFL 60
MS + ST G DL SL SSPEE SG SS IE+ A++ S GD DGG
Sbjct: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGD--DGG-P 57
Query: 61 NDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEET---EREEEEEEMEEEGEEEEQP 117
N STE++ TD+ESS ED + +SM + G+ + +E +R EEEEE EEE EEEEQP
Sbjct: 58 NRTSTESRGTDTESSGEDKDSDSMEDT--GHYSINDENRVHDRSEEEEEEEEE-EEEEQP 114
Query: 118 RMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEAC 177
R + N DQ D+++ALE+W+SSETSALPR RWQ L ALR+R+LGSSARFVYEAC
Sbjct: 115 RRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEAC 174
Query: 178 GARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESG 237
GAR FVQRFRLQ+ L H G V+T+HFNQRGT LAS DDL+V+VWDWVR++PVL+FESG
Sbjct: 175 GARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESG 234
Query: 238 HDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPD 297
H NV QAKF PN GDSTLAMC DGQVRVAEL C+NTKRVA+H+G +H+LALEPD
Sbjct: 235 HKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPD 294
Query: 298 SPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQ 357
SP FL++GEDAVVFTIDLRQDRPASK+VVT+E +KKVGLYTI +NPAN +QFAVGG DQ
Sbjct: 295 SPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQ 354
Query: 358 FVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLF 417
FVRIYDQR+ID+ ENNGVLKKF PHHLV + NITC+VYSHDGTELLASYNDEDIYLF
Sbjct: 355 FVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLF 414
Query: 418 NSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFME 477
NSS SDGAQYVKRYKGHRNN T+K VNFYGP+SEFVVSGSDCGH+F WEKSS QIIQFME
Sbjct: 415 NSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFME 474
Query: 478 GDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNL 537
GD+G +VNCLEPHP+LPVLATSGLD V+IW PTA+ +TELTGLKDVIKKNK+ERDED+L
Sbjct: 475 GDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSL 534
Query: 538 NYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTS-EEEGQDRVQ 596
+ TD FD+ ML F + HL QR H WR+ G D + DES S+SDTS EEEG DRVQ
Sbjct: 535 HQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADS-DESPSSSDTSDEEEGPDRVQ 593
Query: 597 CIPS 600
C+PS
Sbjct: 594 CMPS 597
>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
Length = 860
Score = 127 bits (320), Expect = 2e-29
Identities = 90/314 (28%), Positives = 141/314 (44%), Gaps = 29/314 (9%)
Query: 145 SETSALPRSRWQVLTALRQRQLG--SSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTI 202
S + P W V R+R LG +R G R F+QR +L+ L H G V+TI
Sbjct: 2 SRGGSYPHLLWDV----RKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTI 57
Query: 203 HFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHD 262
+N G + S DD ++++ + +K + SGH N+ AKF P D + C D
Sbjct: 58 CWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGD 117
Query: 263 GQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPA 322
G + + + + H G +E+ P+ PY FL+ GED V D R
Sbjct: 118 GVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR----- 172
Query: 323 SKVVVTRENDK-------KVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKE---- 371
K T+E+ K + ++++ P Y AVG D VRIYD+R + +
Sbjct: 173 IKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNY 232
Query: 372 ----NNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQY 427
G++ +F P HL + +T + YS DG E+L SY+ + IYLF+ D A+
Sbjct: 233 AGRGTTGMVARFIPSHL--NNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPK-DDTARE 289
Query: 428 VKRYKGHRNNDTIK 441
+K + ++
Sbjct: 290 LKTPSAEERREELR 303
Score = 98.2 bits (243), Expect = 2e-20
Identities = 57/150 (38%), Positives = 86/150 (57%), Gaps = 7/150 (4%)
Query: 431 YKGHRNNDT-IKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEP 489
YKGHRN+ T IK NF+G + FV+SGSDCGH+F W++ +++ + +E D +VNCL+P
Sbjct: 713 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADN-HVVNCLQP 769
Query: 490 HPYLPVLATSGLDQHVRIWTPTAKTATELTGLKD-VIKKNK--QERDEDNLNYTDSFDNR 546
HP+ P+LA+SG+D ++IW+P ++ L D VI +N+ E + + SF R
Sbjct: 770 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 829
Query: 547 MLRFFVRHLLQRAHQPGWRDHGAEFPDEEE 576
ML R G E +E+E
Sbjct: 830 MLASLNHIRADRLEGDRSEGSGQENENEDE 859
>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
Length = 880
Score = 127 bits (320), Expect = 2e-29
Identities = 90/314 (28%), Positives = 141/314 (44%), Gaps = 29/314 (9%)
Query: 145 SETSALPRSRWQVLTALRQRQLG--SSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTI 202
S + P W V R+R LG +R G R F+QR +L+ L H G V+TI
Sbjct: 2 SRGGSYPHLLWDV----RKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTI 57
Query: 203 HFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHD 262
+N G + S DD ++++ + +K + SGH N+ AKF P D + C D
Sbjct: 58 CWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGD 117
Query: 263 GQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPA 322
G + + + + H G +E+ P+ PY FL+ GED V D R
Sbjct: 118 GVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR----- 172
Query: 323 SKVVVTRENDK-------KVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKE---- 371
K T+E+ K + ++++ P Y AVG D VRIYD+R + +
Sbjct: 173 IKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNY 232
Query: 372 ----NNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQY 427
G++ +F P HL + +T + YS DG E+L SY+ + IYLF+ D A+
Sbjct: 233 AGRGTTGMVARFIPSHL--NNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPK-DDTARE 289
Query: 428 VKRYKGHRNNDTIK 441
+K + ++
Sbjct: 290 LKTPSAEERREELR 303
Score = 98.2 bits (243), Expect = 2e-20
Identities = 57/150 (38%), Positives = 86/150 (57%), Gaps = 7/150 (4%)
Query: 431 YKGHRNNDT-IKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEP 489
YKGHRN+ T IK NF+G + FV+SGSDCGH+F W++ +++ + +E D +VNCL+P
Sbjct: 733 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADN-HVVNCLQP 789
Query: 490 HPYLPVLATSGLDQHVRIWTPTAKTATELTGLKD-VIKKNK--QERDEDNLNYTDSFDNR 546
HP+ P+LA+SG+D ++IW+P ++ L D VI +N+ E + + SF R
Sbjct: 790 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 849
Query: 547 MLRFFVRHLLQRAHQPGWRDHGAEFPDEEE 576
ML R G E +E+E
Sbjct: 850 MLASLNHIRADRLEGDRSEGSGQENENEDE 879
>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
Length = 676
Score = 107 bits (268), Expect = 2e-23
Identities = 77/267 (28%), Positives = 121/267 (45%), Gaps = 33/267 (12%)
Query: 182 FVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDIN 241
F++R L+ L H+G V+ + +N++G LAS DD IVWD + K +L+ +GH N
Sbjct: 33 FIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTAN 92
Query: 242 VIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYK 301
+ KF P+ GD L D +V V +L + E H +A P P
Sbjct: 93 IFSVKFLPHAGDRILITGAADSKVHVHDL---TVKETIHMFGDHTNRVKRIATAPMWPNT 149
Query: 302 FLTSGEDAVVFTIDLRQDRPASKVVV--TRENDKKVGLYTISMNPANIYQFAVGGHDQFV 359
F ++ ED ++ DLR++ S+V++ T + V +++NP + AVG FV
Sbjct: 150 FWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFV 209
Query: 360 RIYDQRRI---------------------DKKENNGVLKKFTPHHL--VYCDFPTNI--- 393
R+YD R I K +G + + HL D+ +
Sbjct: 210 RLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVL 269
Query: 394 --TCVVYSHDGTELLASYNDEDIYLFN 418
T V +S +GTELL + E +YLF+
Sbjct: 270 VATYVTFSPNGTELLVNMGGEQVYLFD 296
Score = 92.0 bits (227), Expect = 1e-18
Identities = 70/233 (30%), Positives = 108/233 (46%), Gaps = 38/233 (16%)
Query: 383 HLVYCD-FPTNITCVVYS-HDGTELLASYNDEDIYLFNSSLSDGAQ------------YV 428
H CD +IT ++S +DG E + L ++S D Y
Sbjct: 467 HSSACDALGRDITAALFSKNDGEEKKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQ 526
Query: 429 KRYKGHRNNDT-IKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCL 487
RY GH N T IK NF+G ++++VSGSD G F WEK ++ +++ ++GD IVNCL
Sbjct: 527 FRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDE-SIVNCL 585
Query: 488 EPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRM 547
+PHP LATSG+D VR+W P + + +LTG + + ++ +N D + +
Sbjct: 586 QPHPSYCFLATSGIDPVVRLWNPRPE-SEDLTGRVVEDMEGASQANQRRMN-ADPLEVML 643
Query: 548 LRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQCIPS 600
L G+R G L + + E+ + +VQC PS
Sbjct: 644 LNM------------GYRITG--------LSSGGAGASDDEDSSEGQVQCRPS 676
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 72.8 bits (177), Expect = 9e-13
Identities = 80/337 (23%), Positives = 150/337 (44%), Gaps = 40/337 (11%)
Query: 191 LLGSHAGSVSTIHFNQRGTR-LASSGDDLRVIVWDWV-----RQKPVLNFESGHDINVIQ 244
LLG H G V+ I F+ G + L S GDD RV++W R KP+ + H N+
Sbjct: 49 LLG-HFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPI-QLKGEHHSNIFC 106
Query: 245 AKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLT 304
F N G++ + G+D QV + ++ ++ T V H + L++ P + F +
Sbjct: 107 LAF--NSGNTKVFSGGNDEQVILHDVESSE----TLDVFAHEDAVYGLSVSPVNDNIFAS 160
Query: 305 SGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQ 364
S +D V D+R+ + +++ NP A + V ++D
Sbjct: 161 SSDDGRVLIWDIRESPHGEPFCLANYPS---AFHSVMFNPVEPRLLATANSKEGVGLWDI 217
Query: 365 RRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDG 424
R K + +L+ L + V ++ +GT+LLA L++ S
Sbjct: 218 R----KPQSSLLRYGGNLSL------QSAMSVRFNSNGTQLLALRRRLPPVLYDIH-SRL 266
Query: 425 AQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWE-----------KSSSQII 473
+ +G+ N+ T+K F G R ++++SGSD +++ W + +
Sbjct: 267 PVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPADPEAGGIGRVVNGAF 326
Query: 474 QFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTP 510
++G R IVN + +P+ ++ +SG+++ ++IW+P
Sbjct: 327 MVLKGHR-SIVNQVRFNPHTYMICSSGVEKIIKIWSP 362
>gi|153791298 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 64.3 bits (155), Expect = 3e-10
Identities = 79/325 (24%), Positives = 131/325 (40%), Gaps = 36/325 (11%)
Query: 197 GSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTL 256
G+V + FN G + G D + +W+ +R +L SGH V+ A + +S+L
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGT-LLRTYSGHGYEVLDAA--GSFDNSSL 82
Query: 257 AMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDL 316
G D V + ++ + ++ H G + + ++ L+ D+ + D
Sbjct: 83 CSGGGDKAVVLWDVASGQV---VRKFRGHAGKVNTVQFNEEATV-ILSGSIDSSIRCWDC 138
Query: 317 RQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVL 376
R RP + D G+ ++ ++ I +V G VR YD R
Sbjct: 139 RSRRPEPVQTLDEARD---GVSSVKVSDHEILAGSVDGR---VRRYDLRMGQ-------- 184
Query: 377 KKFTPHHLVYCDFPTN-ITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHR 435
++ D+ + ITC +S DG L S D + L + D + + YKGH+
Sbjct: 185 --------LFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDK---DTGELLGEYKGHK 233
Query: 436 NNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPV 495
N + K R VVS S+ G VFFW+ + + G +V L HP P
Sbjct: 234 NQE-YKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVGSG-VVQSLAYHPTEPC 291
Query: 496 LATSGLDQHVRIWTPTAKTATELTG 520
L T+ + V+ W A A + G
Sbjct: 292 LLTA-MGGSVQCWREEAYEAEDGAG 315
Score = 32.7 bits (73), Expect = 0.98
Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 6/48 (12%)
Query: 183 VQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKP 230
V++FR HAG V+T+ FN+ T + S D + WD ++P
Sbjct: 102 VRKFR------GHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRP 143
>gi|14150114 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 64.3 bits (155), Expect = 3e-10
Identities = 79/325 (24%), Positives = 131/325 (40%), Gaps = 36/325 (11%)
Query: 197 GSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTL 256
G+V + FN G + G D + +W+ +R +L SGH V+ A + +S+L
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGT-LLRTYSGHGYEVLDAA--GSFDNSSL 82
Query: 257 AMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDL 316
G D V + ++ + ++ H G + + ++ L+ D+ + D
Sbjct: 83 CSGGGDKAVVLWDVASGQV---VRKFRGHAGKVNTVQFNEEATV-ILSGSIDSSIRCWDC 138
Query: 317 RQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVL 376
R RP + D G+ ++ ++ I +V G VR YD R
Sbjct: 139 RSRRPEPVQTLDEARD---GVSSVKVSDHEILAGSVDGR---VRRYDLRMGQ-------- 184
Query: 377 KKFTPHHLVYCDFPTN-ITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHR 435
++ D+ + ITC +S DG L S D + L + D + + YKGH+
Sbjct: 185 --------LFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLDK---DTGELLGEYKGHK 233
Query: 436 NNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPV 495
N + K R VVS S+ G VFFW+ + + G +V L HP P
Sbjct: 234 NQE-YKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVGSG-VVQSLAYHPTEPC 291
Query: 496 LATSGLDQHVRIWTPTAKTATELTG 520
L T+ + V+ W A A + G
Sbjct: 292 LLTA-MGGSVQCWREEAYEAEDGAG 315
Score = 32.7 bits (73), Expect = 0.98
Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 6/48 (12%)
Query: 183 VQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKP 230
V++FR HAG V+T+ FN+ T + S D + WD ++P
Sbjct: 102 VRKFR------GHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRP 143
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 62.8 bits (151), Expect = 9e-10
Identities = 76/340 (22%), Positives = 139/340 (40%), Gaps = 61/340 (17%)
Query: 186 FRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVW---DWVRQKPVLNFESGHDINV 242
+ L++ L H +VS++ F+ G LASS D + +W D +K + SGH + +
Sbjct: 35 YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI----SGHKLGI 90
Query: 243 IQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKF 302
+ DS L + D + +++ C T +
Sbjct: 91 SDVAW---SSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--------------------- 126
Query: 303 LTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISM-----------NPANIYQFA 351
G VF + P S ++V+ D+ V ++ + +P + F
Sbjct: 127 ---GHSNYVFCCNFN---PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180
Query: 352 VGGHDQFVRIYDQR-RIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYN 410
G YD RI + LK L+ D P ++ V +S +G +LA+
Sbjct: 181 RDGSLIVSSSYDGLCRIWDTASGQCLKT-----LIDDDNPP-VSFVKFSPNGKYILAATL 234
Query: 411 DEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSS 470
D + L++ S + +K Y GH+N NF +++VSGS+ V+ W +
Sbjct: 235 DNTLKLWDYSKG---KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291
Query: 471 QIIQFMEGDRGDIVNCLEPHPYLPVLATSGL--DQHVRIW 508
+I+Q ++G D+V HP ++A++ L D+ +++W
Sbjct: 292 EIVQKLQG-HTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 62.8 bits (151), Expect = 9e-10
Identities = 76/340 (22%), Positives = 139/340 (40%), Gaps = 61/340 (17%)
Query: 186 FRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVW---DWVRQKPVLNFESGHDINV 242
+ L++ L H +VS++ F+ G LASS D + +W D +K + SGH + +
Sbjct: 35 YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI----SGHKLGI 90
Query: 243 IQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKF 302
+ DS L + D + +++ C T +
Sbjct: 91 SDVAW---SSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--------------------- 126
Query: 303 LTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISM-----------NPANIYQFA 351
G VF + P S ++V+ D+ V ++ + +P + F
Sbjct: 127 ---GHSNYVFCCNFN---PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180
Query: 352 VGGHDQFVRIYDQR-RIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYN 410
G YD RI + LK L+ D P ++ V +S +G +LA+
Sbjct: 181 RDGSLIVSSSYDGLCRIWDTASGQCLKT-----LIDDDNPP-VSFVKFSPNGKYILAATL 234
Query: 411 DEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSS 470
D + L++ S + +K Y GH+N NF +++VSGS+ V+ W +
Sbjct: 235 DNTLKLWDYSKG---KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291
Query: 471 QIIQFMEGDRGDIVNCLEPHPYLPVLATSGL--DQHVRIW 508
+I+Q ++G D+V HP ++A++ L D+ +++W
Sbjct: 292 EIVQKLQG-HTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|147904340 WD repeat domain 82 [Homo sapiens]
Length = 313
Score = 61.6 bits (148), Expect = 2e-09
Identities = 70/336 (20%), Positives = 139/336 (41%), Gaps = 40/336 (11%)
Query: 183 VQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLN-FESGHDIN 241
++ FR+ + ++ ++ F+ G + SS DD ++++D KP + + ++
Sbjct: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVD 67
Query: 242 VIQAKFFPNCGDSTLAMCGH--DGQVRVAELINASYCE----NTKRVAKHRGPAHELALE 295
+I+ N T+ + D +R L + Y ++KRV L++
Sbjct: 68 LIRYTHAAN----TVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVA-------LSMS 116
Query: 296 PDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGH 355
P F++ D + DLR + + G S +P + FA G +
Sbjct: 117 PVDD-TFISGSLDKTIRLWDLRSPNCQGLMHLQ-------GKPVCSFDPEGLI-FAAGVN 167
Query: 356 DQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIY 415
+ V++YD R DK G F + C++ T + +S+DG +L S N I
Sbjct: 168 SEMVKLYDLRSFDK----GPFATFKMQYDRTCEW----TGLKFSNDGKLILISTNGSFIR 219
Query: 416 LFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQF 475
L ++ + + G+ N+ + + P S+F++ GS+ G + W S +
Sbjct: 220 LIDAFKG---VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAV 276
Query: 476 MEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPT 511
++G + CL+ +P A++ ++ W PT
Sbjct: 277 LDGKHTGPITCLQFNPKFMTFASA--CSNMAFWLPT 310
>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
Length = 498
Score = 61.6 bits (148), Expect = 2e-09
Identities = 89/372 (23%), Positives = 140/372 (37%), Gaps = 50/372 (13%)
Query: 150 LPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGT 209
L R R L S + + C R F Q +L H V F+ GT
Sbjct: 148 LQRDRCLYHNTKLDNNLDSVSLLIDHVCSRRQFP--CYTQQILTEHCNEVWFCKFSNDGT 205
Query: 210 RLASSGDDLRVIVWDW---VRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDG--- 263
+LA+ D VI+W +L GH V + P+ D+ L CG D
Sbjct: 206 KLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPD--DNYLVACGPDDCSE 263
Query: 264 ----QVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQD 319
V+ EL TK H +A PD +F+T G+ + DL
Sbjct: 264 LWLWNVQTGEL-------RTKMSQSHEDSLTSVAWNPDGK-RFVTGGQRGQFYQCDLD-- 313
Query: 320 RPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKF 379
++ + E + L+ +S + Q +R Y+ +
Sbjct: 314 ---GNLLDSWEGVRVQCLWCLSDGKTVL----ASDTHQRIRGYN------------FEDL 354
Query: 380 TPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDT 439
T ++V D P I S +G L + + ++L++ L D V++Y+G
Sbjct: 355 TDRNIVQEDHP--IMSFTISKNGRLALLNVATQGVHLWD--LQDRV-LVRKYQGVTQGFY 409
Query: 440 IKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLP-VLAT 498
F G +F+ SGS+ V+ W K S I + G VNC+ +P +P ++A+
Sbjct: 410 TIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTG-HTRTVNCVSWNPQIPSMMAS 468
Query: 499 SGLDQHVRIWTP 510
+ D VRIW P
Sbjct: 469 ASDDGTVRIWGP 480
>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
Length = 514
Score = 61.6 bits (148), Expect = 2e-09
Identities = 89/372 (23%), Positives = 140/372 (37%), Gaps = 50/372 (13%)
Query: 150 LPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGT 209
L R R L S + + C R F Q +L H V F+ GT
Sbjct: 164 LQRDRCLYHNTKLDNNLDSVSLLIDHVCSRRQFP--CYTQQILTEHCNEVWFCKFSNDGT 221
Query: 210 RLASSGDDLRVIVWDW---VRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDG--- 263
+LA+ D VI+W +L GH V + P+ D+ L CG D
Sbjct: 222 KLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPD--DNYLVACGPDDCSE 279
Query: 264 ----QVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQD 319
V+ EL TK H +A PD +F+T G+ + DL
Sbjct: 280 LWLWNVQTGEL-------RTKMSQSHEDSLTSVAWNPDGK-RFVTGGQRGQFYQCDLD-- 329
Query: 320 RPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKF 379
++ + E + L+ +S + Q +R Y+ +
Sbjct: 330 ---GNLLDSWEGVRVQCLWCLSDGKTVL----ASDTHQRIRGYN------------FEDL 370
Query: 380 TPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDT 439
T ++V D P I S +G L + + ++L++ L D V++Y+G
Sbjct: 371 TDRNIVQEDHP--IMSFTISKNGRLALLNVATQGVHLWD--LQDRV-LVRKYQGVTQGFY 425
Query: 440 IKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLP-VLAT 498
F G +F+ SGS+ V+ W K S I + G VNC+ +P +P ++A+
Sbjct: 426 TIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTG-HTRTVNCVSWNPQIPSMMAS 484
Query: 499 SGLDQHVRIWTP 510
+ D VRIW P
Sbjct: 485 ASDDGTVRIWGP 496
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/319 (22%), Positives = 136/319 (42%), Gaps = 32/319 (10%)
Query: 191 LLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPN 250
LL H G V F+ G+ LAS+G D +++W+ GH V++ + N
Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHY--N 118
Query: 251 CGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAV 310
S L D V V + + E KR+ H + P T +D
Sbjct: 119 TDGSMLFSASTDKTVAVWD---SETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGT 175
Query: 311 VFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKK 370
V D+R+ + T +N +V ++ N + Q GG D ++++D R+
Sbjct: 176 VKLWDIRK----KAAIQTFQNTYQV--LAVTFNDTS-DQIISGGIDNDIKVWDLRQ---- 224
Query: 371 ENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFN-SSLSDGAQYVK 429
K T + D ++T + S +G+ LL++ D + +++ + + VK
Sbjct: 225 ------NKLTYTMRGHAD---SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVK 275
Query: 430 RYKGHRNN---DTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNC 486
++G+ +N + ++C + P + +GS V+ W+ +S +I+ + G G I N
Sbjct: 276 IFQGNVHNFEKNLLRC--SWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSI-NE 332
Query: 487 LEPHPYLPVLATSGLDQHV 505
+ HP P++ ++ D+ +
Sbjct: 333 VAFHPDEPIIISASSDKRL 351
Score = 34.3 bits (77), Expect = 0.34
Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 20/124 (16%)
Query: 187 RLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWD-----------WVRQKPVLNFE 235
+L Y + HA SV+ + + G+ L S+ D V VWD + Q V NFE
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFE 285
Query: 236 SGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALE 295
N+++ + P+ S +A D V V + + ++ H G +E+A
Sbjct: 286 K----NLLRCSWSPD--GSKIAAGSADRFVYVWDTTSRRI---LYKLPGHAGSINEVAFH 336
Query: 296 PDSP 299
PD P
Sbjct: 337 PDEP 340
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 57.4 bits (137), Expect = 4e-08
Identities = 74/346 (21%), Positives = 139/346 (40%), Gaps = 73/346 (21%)
Query: 186 FRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVW---DWVRQKPVLNFESGHDINV 242
+ L+ L H +VS++ F+ G LASS D +I+W D +K + GH++ +
Sbjct: 31 YALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLY----GHNLEI 86
Query: 243 IQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKF 302
+ DS+ + D + + + C T +
Sbjct: 87 SDVAW---SSDSSRLVSASDDKTLKLWDVRSGKCLKTLK--------------------- 122
Query: 303 LTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISM-----------NPANIYQF- 350
G VF + P S ++++ D+ V ++ + +P + F
Sbjct: 123 ---GHSNYVFCCNFN---PPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN 176
Query: 351 ------AVGGHDQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTE 404
G +D RI+D + LK LV D P ++ V +S +G
Sbjct: 177 CSGSLIVSGSYDGLCRIWDAA------SGQCLKT-----LVDDDNPP-VSFVKFSPNGKY 224
Query: 405 LLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFF 464
+L + D + L++ S + +K Y GH+N NF +++VSGS+ V+
Sbjct: 225 ILTATLDNTLKLWDYSRG---RCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 281
Query: 465 WEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGL--DQHVRIW 508
W + +I+Q ++G D+V HP ++A++ L D+ +++W
Sbjct: 282 WNLQTKEIVQKLQG-HTDVVISAACHPTENLIASAALENDKTIKLW 326
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 54.3 bits (129), Expect = 3e-07
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 9/119 (7%)
Query: 4 QEGSTGGLPDLVTESLFSSPEEQSGVAAVTAA-SSDIEMAATEPSTGDGGDTRDGGFLND 62
QE + G + + LF PE+ V VT S D+ + E + + + G ++
Sbjct: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
Query: 63 ASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGEEEEQPRMCP 121
E + + E ED E E E EE E EEEEEE EEE EEEE+ P
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEE--------EEEEEEEEEEEEEEEEEEEEEEEAAP 309
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 52.8 bits (125), Expect = 9e-07
Identities = 67/286 (23%), Positives = 114/286 (39%), Gaps = 35/286 (12%)
Query: 92 PLVGEETEREEEEEEMEEEGEEEEQPRMCPRCGGTNHDQCLLDEDQALEEWISSETSALP 151
P G + E EEE+EE EEE + + + M P GG N + W+ E A
Sbjct: 118 PSEGSDEEEEEEDEEDEEERKPQLELAMVPHYGGIN---------RVRVSWLGEEPVA-- 166
Query: 152 RSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQ----YLLGSHAGSVSTIHFNQR 207
W + L + V E F++ + Q + H G + ++ R
Sbjct: 167 -GVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPR 225
Query: 208 GTRLASSGD-DLRVIVW------DW-VRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMC 259
T +GD + +W W V Q+P + GH +V ++ P ++ A C
Sbjct: 226 VTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFV----GHTRSVEDLQWSPT-ENTVFASC 280
Query: 260 GHDGQVRVAELINA--SYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLR 317
D +R+ ++ A C T A H G + ++ P+ L+ G+D + DLR
Sbjct: 281 SADASIRIWDIRAAPSKACMLTTATA-HDGDVNVISWSRREPF-LLSGGDDGALKIWDLR 338
Query: 318 QDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYD 363
Q + S V +++ V ++ +P + FA G D + +D
Sbjct: 339 QFKSGSPVATFKQHVAPV--TSVEWHPQDSGVFAASGADHQITQWD 382
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 51.6 bits (122), Expect = 2e-06
Identities = 88/381 (23%), Positives = 134/381 (35%), Gaps = 55/381 (14%)
Query: 22 SPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVEL 81
S EE++G + S A DG D D L+D + D D +
Sbjct: 50 SDEEETGSPSEDGMQSARTQARPREPLEDG-DPEDDRTLDDDELAEYDLDKYDEEGDPDA 108
Query: 82 ESMGEGLFGYPLVGEETERE----EEEEEMEEEGEEEEQPRMCPRCGGTNHDQCLLD--- 134
E++GE L G + G + ++ E+ E E + CG DQC L+
Sbjct: 109 ETLGESLLGLTVYGSNDQDPYVTLKDTEQYEREDFLIKPSDNLIVCGRAEQDQCNLEVHV 168
Query: 135 ---EDQALEEWISSETSALPRS-RWQVLTALRQRQLGSSARFVYEACGART--------- 181
E+ + SA P S W G+ Y A G T
Sbjct: 169 YNQEEDSFYVHHDILLSAYPLSVEWLNFDPSPDDSTGN-----YIAVGNMTPVIEVWDLD 223
Query: 182 FVQRFRLQYLLGS------------------HAGSVSTIHFNQRGTR-LASSGDDLRVIV 222
V + LGS H +V + +N+ LAS+ D VI+
Sbjct: 224 IVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVIL 283
Query: 223 WDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRV 282
WD KP + + H V +F P TL +D V L + + + R+
Sbjct: 284 WDMSLGKPAASL-AVHTDKVQTLQFHP-FEAQTLISGSYDKSV---ALYDCRSPDESHRM 338
Query: 283 AKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISM 342
+ G + SP FL S +D V+ +D R D+P + ND+ GL S
Sbjct: 339 WRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPI--FTLNAHNDEISGLDLSSQ 396
Query: 343 NPANIYQFAVGGHDQFVRIYD 363
+ D++V+I+D
Sbjct: 397 IKGCL---VTASADKYVKIWD 414
>gi|8922301 WD repeat domain 70 [Homo sapiens]
Length = 654
Score = 48.9 bits (115), Expect = 1e-05
Identities = 75/319 (23%), Positives = 118/319 (36%), Gaps = 42/319 (13%)
Query: 198 SVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLN-FESGHDINVIQAKF--FPNCGDS 254
+VS + + G RL + G D V WD+ F S Q K + N GD
Sbjct: 184 TVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKSLQYSNTGDM 243
Query: 255 TLAMCG--------HDGQVRVAELINAS-YCENTKRVAKHRGPAHELALEPDSPYKFLTS 305
L + G DG V E I Y + H H + P +F+T
Sbjct: 244 ILVVSGSSQAKVIDRDG-FEVMECIKGDQYIVDMANTKGHTAMLHTGSWHPKIKGEFMTC 302
Query: 306 GEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQR 365
DA V T ++ + V R K + T + A + ++I+D+
Sbjct: 303 SNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWDR- 361
Query: 366 RIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDE-----DIYLFNSS 420
N V KF H+ D T+ +CV +S+DG L + D+ DI FN
Sbjct: 362 ------NLTVHPKF--HYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKP 413
Query: 421 LSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSD------CGHVFFWEKSSSQIIQ 474
L + + T C + P + +V+G+ G + F+E+ + Q +
Sbjct: 414 LFSASGLPTMFP-----MTDCC---FSPDDKLIVTGTSIQRGCGSGKLVFFERRTFQRVY 465
Query: 475 FMEGDRGDIVNCLEPHPYL 493
++ +V CL HP L
Sbjct: 466 EIDITDASVVRCLW-HPKL 483
Score = 38.1 bits (87), Expect = 0.023
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 15/87 (17%)
Query: 45 EPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVEL--------------ESMGEGLFG 90
EP++ RD + T + ++ S S D EL M E + G
Sbjct: 81 EPTSSRSNVVRDCSKSSSRDTSSSESEQSSDSSDDELIGPPLPPKMVGKPVNFMEEDILG 140
Query: 91 YPLVGEETEREEEEEEMEEEGEEEEQP 117
PL E EEE EE EEE EEEE P
Sbjct: 141 -PLPPPLNEEEEEAEEEEEEEEEEENP 166
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 48.1 bits (113), Expect = 2e-05
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 4/78 (5%)
Query: 432 KGHRNNDTIKCVNFY-GPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPH 490
+GH + C+++Y G +++SG+D V W+ + +Q +EG + V+C H
Sbjct: 182 EGHEKG--VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQN-VSCASFH 238
Query: 491 PYLPVLATSGLDQHVRIW 508
P LP++ T D VRIW
Sbjct: 239 PELPIIITGSEDGTVRIW 256
Score = 41.2 bits (95), Expect = 0.003
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 32/255 (12%)
Query: 220 VIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENT 279
V VW+ Q V FE D+ V AKF + + D Q+RV N + E
Sbjct: 39 VCVWNHETQTLVKTFEVC-DLPVRAAKFVAR--KNWVVTGADDMQIRV---FNYNTLERV 92
Query: 280 KRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYT 339
H +A+ P P+ LTS +D ++ D + S+V + +
Sbjct: 93 HMFEAHSDYIRCIAVHPTQPF-ILTSSDDMLIKLWDWDKKWSCSQVFEGHTHY----VMQ 147
Query: 340 ISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYS 399
I +NP + QFA D+ ++++ ++ N L+ + C+ Y
Sbjct: 148 IVINPKDNNQFASASLDRTIKVW---QLGSSSPNFTLE----------GHEKGVNCIDYY 194
Query: 400 HDGTE--LLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGS 457
G + L++ +D + +++ V+ +GH N + C +F+ P +++GS
Sbjct: 195 SGGDKPYLISGADDRLVKIWDYQ---NKTCVQTLEGHAQN--VSCASFH-PELPIIITGS 248
Query: 458 DCGHVFFWEKSSSQI 472
+ G V W S+ ++
Sbjct: 249 EDGTVRIWHSSTYRL 263
Score = 33.5 bits (75), Expect = 0.57
Identities = 15/60 (25%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 449 RSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIW 508
R +VV+G+D + + ++ + + E D + C+ HP P + TS D +++W
Sbjct: 68 RKNWVVTGADDMQIRVFNYNTLERVHMFEA-HSDYIRCIAVHPTQPFILTSSDDMLIKLW 126
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 46.6 bits (109), Expect = 7e-05
Identities = 62/303 (20%), Positives = 122/303 (40%), Gaps = 76/303 (25%)
Query: 186 FRLQYLLGSHAGSVSTIHFNQRGTRL-ASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQ 244
++LQ ++ +HA +VS++ + RL A+ GDD RV +W IN
Sbjct: 11 WKLQEIV-AHASNVSSLVLGKASGRLLATGGDDCRVNLWS---------------INK-- 52
Query: 245 AKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLT 304
PNC +++ GH V L ++P + +
Sbjct: 53 ----PNC---IMSLTGHTSPVESVRL--------------------------NTPEELIV 79
Query: 305 SGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQ 364
+G + + D A+K++ T K + ++ +P + A G D ++++D
Sbjct: 80 AGSQSGSIRV---WDLEAAKILRTLMGHK-ANICSLDFHPYGEF-VASGSQDTNIKLWDI 134
Query: 365 RRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDG 424
RR G + ++ H + C+ +S DG L ++ +D + L++ +
Sbjct: 135 RR------KGCVFRYRGHSQA-------VRCLRFSPDGKWLASAADDHTVKLWDLT---A 178
Query: 425 AQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIV 484
+ + + GH + V F+ P + SGS + FW+ Q++ +EG+ G +
Sbjct: 179 GKMMSEFPGHTG--PVNVVEFH-PNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVR 235
Query: 485 NCL 487
+ L
Sbjct: 236 SVL 238
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 428 VKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCL 487
V RY+GH + ++C+ F P +++ S +D V W+ ++ +++ G G VN +
Sbjct: 140 VFRYRGH--SQAVRCLRF-SPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP-VNVV 195
Query: 488 EPHPYLPVLATSGLDQHVRIW 508
E HP +LA+ D+ +R W
Sbjct: 196 EFHPNEYLLASGSSDRTIRFW 216
Score = 39.7 bits (91), Expect = 0.008
Identities = 16/58 (27%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Query: 451 EFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIW 508
E +V+GS G + W+ +++I++ + G + +I + L+ HPY +A+ D ++++W
Sbjct: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICS-LDFHPYGEFVASGSQDTNIKLW 132
Score = 35.4 bits (80), Expect = 0.15
Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 423 DGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGD 482
+ A+ ++ GH+ N C + P EFV SGS ++ W+ + F
Sbjct: 93 EAAKILRTLMGHKANI---CSLDFHPYGEFVASGSQDTNIKLWDIRRKGCV-FRYRGHSQ 148
Query: 483 IVNCLEPHPYLPVLATSGLDQHVRIWTPTA-KTATELTG 520
V CL P LA++ D V++W TA K +E G
Sbjct: 149 AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPG 187
Score = 34.3 bits (77), Expect = 0.34
Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 6/103 (5%)
Query: 195 HAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDS 254
H+ +V + F+ G LAS+ DD V +WD K + F GH V +F PN +
Sbjct: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVVEFHPN--EY 202
Query: 255 TLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPD 297
LA D +R +L + + GP + PD
Sbjct: 203 LLASGSSDRTIRFWDL---EKFQVVSCIEGEPGPVRSVLFNPD 242
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 46.2 bits (108), Expect = 9e-05
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 12/145 (8%)
Query: 366 RIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGA 425
R+++KE +L H V D + ++ DG+ +L S + D L L D
Sbjct: 7 RVNEKEIGKLLLNLVDHTEVVRD-------LTFAPDGSLILVSAS-RDKTLRVWDLKDDG 58
Query: 426 QYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVN 485
+K +GH+N C + P S + S VF W +I+ +EG D+V
Sbjct: 59 NMMKVLRGHQNW-VYSCA--FSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVA 115
Query: 486 CLEPHPYLPVLATSGLDQHVRIWTP 510
C + P +LAT+ D V IW P
Sbjct: 116 C-DFSPDGALLATASYDTRVYIWDP 139
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 46.2 bits (108), Expect = 9e-05
Identities = 36/124 (29%), Positives = 52/124 (41%), Gaps = 9/124 (7%)
Query: 1 MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFL 60
M +EG T G + +S + E G + E GD + D G +
Sbjct: 756 MPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDN-EGEDEGEI 814
Query: 61 NDASTENQNTDSESSSEDVELESMGEGLFGYPLV--------GEETEREEEEEEMEEEGE 112
+ E + + E+ S+++ E+ GE V G+ E EEEEEE EEE E
Sbjct: 815 HAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE 874
Query: 113 EEEQ 116
EEEQ
Sbjct: 875 EEEQ 878
Score = 36.2 bits (82), Expect = 0.089
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 13/65 (20%)
Query: 50 DGGDTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEE 109
D DGG + +E + + E E+ E E E+ E EEEEEE EE
Sbjct: 844 DEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEE-------------EQEEEEEEEEEEEE 890
Query: 110 EGEEE 114
+G EE
Sbjct: 891 KGNEE 895
Score = 30.4 bits (67), Expect = 4.9
Identities = 29/131 (22%), Positives = 46/131 (35%), Gaps = 13/131 (9%)
Query: 24 EEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVELES 83
E G V A S EM E T G+T + T+++ E+ E E+
Sbjct: 739 ENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDEN 798
Query: 84 MGEGLFGYP-------------LVGEETEREEEEEEMEEEGEEEEQPRMCPRCGGTNHDQ 130
EG + G E E E +E E GE + + GG++
Sbjct: 799 EAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGD 858
Query: 131 CLLDEDQALEE 141
+E++ E+
Sbjct: 859 SEEEEEEEEEQ 869
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 46.2 bits (108), Expect = 9e-05
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 12 PDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTD 71
P+ +S E+ G+ AS + + E ++ + G + G + + NT+
Sbjct: 140 PERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTE 199
Query: 72 SESSS------EDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGEEEE 115
+E ED E+E E GEE E EEEEEE EEE EEEE
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
Score = 43.1 bits (100), Expect = 7e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Query: 37 SDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLVGE 96
SD E ++ S G +T + + E E + ED E++ GE E
Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEE--------E 232
Query: 97 ETEREEEEEEMEEEGEEEEQPRMCPRCGGTNHD 129
E E EEEEEE EEE EE EQ + G ++D
Sbjct: 233 EEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 46.2 bits (108), Expect = 9e-05
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 12 PDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTD 71
P+ +S E+ G+ AS + + E ++ + G + G + + NT+
Sbjct: 140 PERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTE 199
Query: 72 SESSS------EDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGEEEE 115
+E ED E+E E GEE E EEEEEE EEE EEEE
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
Score = 43.1 bits (100), Expect = 7e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Query: 37 SDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLVGE 96
SD E ++ S G +T + + E E + ED E++ GE E
Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEE--------E 232
Query: 97 ETEREEEEEEMEEEGEEEEQPRMCPRCGGTNHD 129
E E EEEEEE EEE EE EQ + G ++D
Sbjct: 233 EEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 45.8 bits (107), Expect = 1e-04
Identities = 76/324 (23%), Positives = 138/324 (42%), Gaps = 35/324 (10%)
Query: 193 GSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCG 252
G H G V++ F+ G L + +D V W+ R +L GH V +F P+
Sbjct: 18 GQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWE-TRSGQLLWRLGGHTGPVKFCRFSPDGH 76
Query: 253 DSTLAMCGHDGQVRVAELINASYCENTKRVAK-HRGPAHELALEPDSPYKFLTSGEDAVV 311
A C D VR+ ++ A RV K H+ ++ PDS + + G D V
Sbjct: 77 LFASASC--DCTVRLWDVARA----KCLRVLKGHQRSVETVSFSPDS-RQLASGGWDKRV 129
Query: 312 FTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKE 371
D++ + +V R++ + + +P + A G D V I+D R +
Sbjct: 130 MLWDVQSGQMLRLLVGHRDS-----IQSSDFSP-TVNCLATGSWDSTVHIWDLRMVTPAV 183
Query: 372 NNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYN-DEDIYLFNSSLSDGAQYVKR 430
++ L+ + NI+C+ YS G LLAS + D+ I+++ + S + +
Sbjct: 184 SHQALEGHS----------ANISCLCYSASG--LLASGSWDKTIHIWKPTTS---SLLIQ 228
Query: 431 YKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPH 490
KGH +K + F P ++ S V W+ ++ + ++ ++G D+ +
Sbjct: 229 LKGHVT--WVKSIAF-SPDELWLASAGYSRMVKVWDCNTGKCLETLKGVL-DVAHTCAFT 284
Query: 491 PYLPVLATSGLDQHVRIWTPTAKT 514
P +L + DQ R + T+K+
Sbjct: 285 PDGKILVSGAADQTRRQISRTSKS 308
Score = 39.7 bits (91), Expect = 0.008
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 7/90 (7%)
Query: 183 VQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINV 242
V R + +L H SV T+ F+ +LAS G D RV++WD V+ +L GH ++
Sbjct: 92 VARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD-VQSGQMLRLLVGHRDSI 150
Query: 243 IQAKFFP--NCGDSTLAMCGHDGQVRVAEL 270
+ F P NC LA D V + +L
Sbjct: 151 QSSDFSPTVNC----LATGSWDSTVHIWDL 176
Score = 38.1 bits (87), Expect = 0.023
Identities = 38/136 (27%), Positives = 55/136 (40%), Gaps = 7/136 (5%)
Query: 187 RLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAK 246
+L + LG H G V F+ G AS+ D V +WD R K L GH +V
Sbjct: 54 QLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVRLWDVARAK-CLRVLKGHQRSVETVS 112
Query: 247 FFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSG 306
F P+ LA G D +V + ++ + + + + HR P + T
Sbjct: 113 FSPD--SRQLASGGWDKRVMLWDVQSG---QMLRLLVGHRDSIQSSDFSP-TVNCLATGS 166
Query: 307 EDAVVFTIDLRQDRPA 322
D+ V DLR PA
Sbjct: 167 WDSTVHIWDLRMVTPA 182
>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
Length = 1083
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 53 DTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGE 112
D+ D F + +E +++D E + D E S EE E EEEE + EEE E
Sbjct: 3 DSEDSNFSEEEDSE-RSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEE 61
Query: 113 EEEQPRMCPRCGGTNHDQCLLDEDQALEE 141
++++P PR GG D+ +D++ E+
Sbjct: 62 DDDRPPKKPRHGGFILDEADVDDEYEDED 90
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 53 DTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGE 112
D+ D F + +E +++D E + D E S EE E EEEE + EEE E
Sbjct: 3 DSEDSNFSEEEDSE-RSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEE 61
Query: 113 EEEQPRMCPRCGGTNHDQCLLDEDQALEE 141
++++P PR GG D+ +D++ E+
Sbjct: 62 DDDRPPKKPRHGGFILDEADVDDEYEDED 90
>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 53 DTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGE 112
D+ D F + +E +++D E + D E S EE E EEEE + EEE E
Sbjct: 3 DSEDSNFSEEEDSE-RSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEE 61
Query: 113 EEEQPRMCPRCGGTNHDQCLLDEDQALEE 141
++++P PR GG D+ +D++ E+
Sbjct: 62 DDDRPPKKPRHGGFILDEADVDDEYEDED 90
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,516,581
Number of Sequences: 37866
Number of extensions: 1185633
Number of successful extensions: 15548
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 290
Number of HSP's successfully gapped in prelim test: 262
Number of HSP's that attempted gapping in prelim test: 8781
Number of HSP's gapped (non-prelim): 3595
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.