Guide to the Human Genome
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Name: PDE5A Sequence: fasta or formatted (875aa) NCBI GI: 61744435
Description:

phosphodiesterase 5A isoform 1

Referenced in:

Cyclic Nucleotides
Common Drug Targets

Other entries for this name:
alt prot [833aa] phosphodiesterase 5A isoform 2
alt prot [823aa] phosphodiesterase 5A isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.0         61           3
 C cysteine            2.9         25           1
 D aspartate           5.6         49           2
 E glutamate           8.1         71           3
 F phenylalanine       4.8         42           2
 G glycine             3.9         34           2
 H histidine           3.0         26           3
 I isoleucine          6.3         55           2
 K lysine              6.6         58           2
 L leucine             9.8         86           2
 M methionine          2.5         22           1
 N asparagine          5.4         47           2
 P proline             3.3         29           2
 Q glutamine           6.5         57           4
 R arginine            4.7         41           2
 S serine              6.4         56           2
 T threonine           4.9         43           2
 V valine              5.3         46           2
 W tryptophan          1.0          9           1
 Y tyrosine            2.1         18           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   phosphodiesterase 5A isoform 1 
PDE5A                 0.941   phosphodiesterase 5A isoform 2 
PDE5A                 0.937   phosphodiesterase 5A isoform 3 
PDE11A                0.328   phosphodiesterase 11A isoform 4 
PDE11A                0.283   phosphodiesterase 11A isoform 3 
PDE11A                0.247   phosphodiesterase 11A isoform 2 
PDE11A                0.221   phosphodiesterase 11A isoform 1 
PDE6B                 0.219   phosphodiesterase 6B isoform 2 
PDE6B                 0.219   phosphodiesterase 6B isoform 1 
PDE6A                 0.212   phosphodiesterase 6A 
PDE6C                 0.202   phosphodiesterase 6C 
PDE10A                0.182   phosphodiesterase 10A isoform 2 
PDE10A                0.182   phosphodiesterase 10A isoform 1 
PDE6B                 0.165   phosphodiesterase 6B isoform 3 
PDE2A                 0.151   phosphodiesterase 2A isoform 3 
PDE2A                 0.151   phosphodiesterase 2A isoform 2 
PDE2A                 0.151   phosphodiesterase 2A isoform 1 
PDE4C                 0.065   phosphodiesterase 4C isoform PDE4C-2 
PDE4C                 0.065   phosphodiesterase 4C isoform PDE4C-3 
PDE4C                 0.065   phosphodiesterase 4C isoform PDE4C-1 
PDE9A                 0.064   phosphodiesterase 9A isoform g 
PDE9A                 0.064   phosphodiesterase 9A isoform g 
PDE9A                 0.064   phosphodiesterase 9A isoform o 
PDE9A                 0.064   phosphodiesterase 9A isoform n 
PDE9A                 0.064   phosphodiesterase 9A isoform m 
PDE9A                 0.064   phosphodiesterase 9A isoform j 
PDE9A                 0.064   phosphodiesterase 9A isoform g 
PDE9A                 0.064   phosphodiesterase 9A isoform l 
PDE9A                 0.064   phosphodiesterase 9A isoform k 
PDE9A                 0.064   phosphodiesterase 9A isoform j 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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