BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|61743975 SORCS receptor 1 isoform b [Homo sapiens] (1198 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|61743975 SORCS receptor 1 isoform b [Homo sapiens] 2429 0.0 gi|61743973 SORCS receptor 1 isoform a [Homo sapiens] 2289 0.0 gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo sapiens] 1592 0.0 gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] 1011 0.0 gi|4507157 sortilin-related receptor containing LDLR class A rep... 254 4e-67 gi|17149834 sortilin 1 preproprotein [Homo sapiens] 226 1e-58 gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ... 42 0.005 gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ... 42 0.005 gi|239508962 PREDICTED: hypothetical protein [Homo sapiens] 42 0.005 gi|239754797 PREDICTED: hypothetical protein [Homo sapiens] 40 0.013 gi|239749325 PREDICTED: hypothetical protein [Homo sapiens] 40 0.013 gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo ... 40 0.013 gi|239743415 PREDICTED: hypothetical protein [Homo sapiens] 40 0.013 gi|239509122 PREDICTED: hypothetical protein [Homo sapiens] 40 0.013 gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo sa... 38 0.051 gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] 36 0.25 gi|41352718 deltex homolog 1 [Homo sapiens] 36 0.25 gi|4503657 forkhead box H1 [Homo sapiens] 35 0.33 gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens] 35 0.33 gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens] 35 0.33 gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens] 35 0.33 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 35 0.43 gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 35 0.43 gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 35 0.56 gi|169204930 PREDICTED: hypothetical protein [Homo sapiens] 35 0.56 gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] 35 0.56 gi|169164783 PREDICTED: hypothetical protein [Homo sapiens] 35 0.56 gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] 35 0.56 gi|169163482 PREDICTED: hypothetical protein [Homo sapiens] 35 0.56 gi|5803080 macrophage receptor with collagenous structure [Homo ... 35 0.56 >gi|61743975 SORCS receptor 1 isoform b [Homo sapiens] Length = 1198 Score = 2429 bits (6296), Expect = 0.0 Identities = 1198/1198 (100%), Positives = 1198/1198 (100%) Query: 1 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG 60 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG Sbjct: 1 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG 60 Query: 61 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER 120 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER Sbjct: 61 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER 120 Query: 121 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW 180 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW Sbjct: 121 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW 180 Query: 181 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK 240 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK Sbjct: 181 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK 240 Query: 241 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA 300 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA Sbjct: 241 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA 300 Query: 301 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ 360 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ Sbjct: 301 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ 360 Query: 361 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE 420 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE Sbjct: 361 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE 420 Query: 421 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL 480 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL Sbjct: 421 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL 480 Query: 481 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI 540 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI Sbjct: 481 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI 540 Query: 541 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM 600 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM Sbjct: 541 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM 600 Query: 601 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL 660 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL Sbjct: 601 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL 660 Query: 661 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP 720 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP Sbjct: 661 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP 720 Query: 721 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG 780 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG Sbjct: 721 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG 780 Query: 781 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG 840 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG Sbjct: 781 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG 840 Query: 841 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV 900 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV Sbjct: 841 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV 900 Query: 901 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG 960 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG Sbjct: 901 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG 960 Query: 961 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI 1020 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI Sbjct: 961 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI 1020 Query: 1021 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL 1080 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL Sbjct: 1021 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL 1080 Query: 1081 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKIPGINVYAQMQNEKE 1140 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKIPGINVYAQMQNEKE Sbjct: 1081 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKIPGINVYAQMQNEKE 1140 Query: 1141 QEMISPVSHSESRPNVPQTELRRPGQLIDEKVESQLIGSISIVAENQSTKEIPTYVNV 1198 QEMISPVSHSESRPNVPQTELRRPGQLIDEKVESQLIGSISIVAENQSTKEIPTYVNV Sbjct: 1141 QEMISPVSHSESRPNVPQTELRRPGQLIDEKVESQLIGSISIVAENQSTKEIPTYVNV 1198 >gi|61743973 SORCS receptor 1 isoform a [Homo sapiens] Length = 1168 Score = 2289 bits (5931), Expect = 0.0 Identities = 1124/1126 (99%), Positives = 1126/1126 (100%) Query: 1 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG 60 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG Sbjct: 1 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG 60 Query: 61 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER 120 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER Sbjct: 61 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER 120 Query: 121 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW 180 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW Sbjct: 121 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW 180 Query: 181 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK 240 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK Sbjct: 181 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK 240 Query: 241 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA 300 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA Sbjct: 241 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA 300 Query: 301 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ 360 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ Sbjct: 301 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ 360 Query: 361 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE 420 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE Sbjct: 361 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE 420 Query: 421 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL 480 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL Sbjct: 421 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL 480 Query: 481 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI 540 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI Sbjct: 481 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI 540 Query: 541 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM 600 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM Sbjct: 541 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM 600 Query: 601 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL 660 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL Sbjct: 601 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL 660 Query: 661 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP 720 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP Sbjct: 661 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP 720 Query: 721 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG 780 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG Sbjct: 721 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG 780 Query: 781 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG 840 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG Sbjct: 781 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG 840 Query: 841 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV 900 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV Sbjct: 841 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV 900 Query: 901 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG 960 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG Sbjct: 901 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG 960 Query: 961 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI 1020 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI Sbjct: 961 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI 1020 Query: 1021 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL 1080 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL Sbjct: 1021 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL 1080 Query: 1081 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKI 1126 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKR++ Sbjct: 1081 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRV 1126 >gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo sapiens] Length = 1222 Score = 1592 bits (4123), Expect = 0.0 Identities = 761/1108 (68%), Positives = 912/1108 (82%), Gaps = 2/1108 (0%) Query: 93 RGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGTRER-DPDKAT 151 RG G RR R ERG+ + +P R G+RE +A Sbjct: 115 RGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAG 174 Query: 152 RFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRST 211 E+LRL ST+FALTGDSAHNQAMVHWSGHNSSVILILTKLYD+NLGS+TESSLWRST Sbjct: 175 GSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRST 234 Query: 212 DYGTTYEKLNDKVGLKTILSYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLN 271 DYGTTYEKLNDKVGLKT+LSYLYV PTNKRKIMLL+DPE+ESS+LISSDEGATYQKYRL Sbjct: 235 DYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLT 294 Query: 272 FYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDL 331 FYIQSLLFHPKQEDW+LAYS DQKLYSS +FGRRWQL+ E + PNRFYWSV G +KE DL Sbjct: 295 FYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADL 354 Query: 332 VHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGGRPHYY 391 VH+E RT DG++HYLTCR+Q C E R+ PF ID SL+VQD Y+F+Q+T+ GR YY Sbjct: 355 VHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYY 414 Query: 392 VSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLA 451 VSYRR AFAQ+KLPKY+LPKDMH+ISTDENQVFAAVQEWNQNDTYNLYISDTRG+YFTLA Sbjct: 415 VSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLA 474 Query: 452 LENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDTDL 511 +EN++SSRG GNI+I+LYEVAGIKG+FLANKK+D+QVKT+ITYNKGRDWRLLQAPD DL Sbjct: 475 MENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDL 534 Query: 512 RGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSELSDTDISMFVS 571 RG PVHCLLP+CSLHLHL++SENPY+SG I+SK+TAP ++VA+GNIG ELS TDI +F+S Sbjct: 535 RGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFIS 594 Query: 572 SDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLF 631 SD GNTWRQIF+EE++V +LD GG LVAMKHT LP+RHLW+SFDEG SW KY FTS+PLF Sbjct: 595 SDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLF 654 Query: 632 VDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQGEACI 691 VDG L E G ET IMTVFGHFS RSEWQLVKVDYKSIF R C +EDY+ W L +QGE C+ Sbjct: 655 VDGALVEAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCV 714 Query: 692 MGAKRIYKKRKSERKCMQGK-YAGAMESEPCVCTEADFDCDYGYERHSNGQCLPAFWFNP 750 MG ++I+KKRK +C G+ ++G++ SEPCVC DF+CDYGYERH QC+PAFW+NP Sbjct: 715 MGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNP 774 Query: 751 SSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLT 810 +S SKDCSLGQSYLNSTGYR++VSNNCTDG+RE+YTAK Q CPGKAPRGL +VT DG+L Sbjct: 775 ASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLV 834 Query: 811 AEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQ 870 AEQGHN T ++ +EEGD+QRT IQ+DFGDGIAVSY N S +EDGIKHVY++ GIF+VT Sbjct: 835 AEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAY 894 Query: 871 VDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNN 930 +N+LGSD+AVL+LHV CP+EHVHL +PFV +NKEVN +AV+WPSQ+GTLTY WW+GN+ Sbjct: 895 AENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNS 954 Query: 931 TEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLSFSPNLDDY 990 T+PLITL+ SISF F +EG +TITVQV+AGNA++QDTK IAV+E F+S LSFSPNLD + Sbjct: 955 TKPLITLDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYH 1014 Query: 991 NPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLPYQDPAGENKRST 1050 NPDIPEWR+DIG VIK++LV+ T VP IL+AV PGLPT+AELF+LP ++ K + Sbjct: 1015 NPDIPEWRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNE 1074 Query: 1051 DDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVV 1110 DLEQI E L + LNQN V FELKPGV+V+V+ LT APLVD + HS SAMLMLLSVV Sbjct: 1075 GDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVV 1134 Query: 1111 FVGLAVFVIYKFKRKIPGINVYAQMQNEKEQEMISPVSHSESRPNVPQTELRRPGQLIDE 1170 FVGLAVF+IYKFKRKIP IN+YAQ+Q++KEQEMI VS SE+ P + ++ P +L+D+ Sbjct: 1135 FVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDK 1194 Query: 1171 KVESQLIGSISIVAENQSTKEIPTYVNV 1198 ++++++IG I+ +A ++STKEIP +V Sbjct: 1195 ELDTRVIGGIATIANSESTKEIPNCTSV 1222 >gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] Length = 1159 Score = 1011 bits (2613), Expect = 0.0 Identities = 526/1138 (46%), Positives = 731/1138 (64%), Gaps = 37/1138 (3%) Query: 33 GGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERA 92 G G +P P + P P R+P + PL++ L A G S E Sbjct: 12 GPGPTARAPSPGAPP--------------PPRSPRSR-PLLLLLLLLGACGAAGRSPEPG 56 Query: 93 R-GTGASMAVAARS---GRRRRSGADQEKAERGE----GASRSPRGVLRDGGQQEPGTR- 143 R G A + RS GR G + +A E G S P + G G R Sbjct: 57 RLGPHAQLTRVPRSPPAGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRR 116 Query: 144 -ERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSI 202 ER A ++ L ST+F L GD+ HNQAMVHW+G NSSVILILTK Y ++G + Sbjct: 117 WERAAPLAGVASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKV 176 Query: 203 TESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNKRKIMLLTDP--EIESSLLISSD 260 ESSLWRS+D+GT+Y KL + G+ T++ Y+CPTNKRK++L++ + + SL +S+D Sbjct: 177 LESSLWRSSDFGTSYTKLTLQPGVTTVIDNFYICPTNKRKVILVSSSLSDRDQSLFLSAD 236 Query: 261 EGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYW 320 EGAT+QK + F++++L+FHPK+ED +LAY+++ KLY S++ G++W L+QE V + +W Sbjct: 237 EGATFQKQPIPFFVETLIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQERVTKDHVFW 296 Query: 321 SVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFV 380 SV G + +PDLVH+EA+ + G Y+TC + NC+E PF G ID SL VQD Y+F Sbjct: 297 SVSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFF 356 Query: 381 QLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYI 440 + TS + YYVSYRRN F MKLPKYALPKD+ +ISTDE+QVF AVQEW Q DTYNLY Sbjct: 357 KATSANQTKYYVSYRRNEFVLMKLPKYALPKDLQIISTDESQVFVAVQEWYQMDTYNLYQ 416 Query: 441 SDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRD 500 SD RGV + L L++V+SSR E +++ID+ EV G+KG+FLAN+KID +V T ITYNKGRD Sbjct: 417 SDPRGVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVMTLITYNKGRD 476 Query: 501 WRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSE 560 W L+ P D+ G P +C P C LHLHL+ ++NPY SG + +KDTAP +I+ +GN+GS+ Sbjct: 477 WDYLRPPSMDMNGKPTNCKPPDCHLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLGSQ 536 Query: 561 LSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSW 620 L + M+++SD G+TWRQ+FEEEH +LYLD GGV+VA+K TS+P++ L S DEG +W Sbjct: 537 LVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEGLTW 596 Query: 621 SKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRP 680 S ++FTS +FVDG+L EPG+ETL+MTVFGH S RS+W+LVKVD++ F R+C EEDY Sbjct: 597 STHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFSRQCGEEDYSS 656 Query: 681 WQLHS-QGEACIMGAKRIYKKRKSERKCMQGK-YAGAMESEPCVCTEADFDCDYGYERHS 738 W+L + QG+ CIMG +R ++KRKS C++G+ + A+ S C C ++DF CDYG+ER S Sbjct: 657 WELSNLQGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDFLCDYGFERSS 716 Query: 739 NGQ-----CLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCP 793 + + C FWFNP S DC+LGQ+Y +S GYRKVVSN C GV Q + +CP Sbjct: 717 SSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDMQQSQVQLQCP 776 Query: 794 GKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMED 853 PRGL++ + G +V +V+ E+GDV T QVD GDG YVNL+ + Sbjct: 777 LTPPRGLQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGE 836 Query: 854 GIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVL 913 I+H Y++ GI+RV+V+ +N+ G D AVL++ V PL+ ++L + V N+EVN TAVL Sbjct: 837 PIRHRYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLTAVL 896 Query: 914 WPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVY 973 P + WW G++ +PL++L+ S++ RF+ G +TVQ + GN++LQD++ + V Sbjct: 897 LPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVLRVL 956 Query: 974 EEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAE 1033 ++F+ + L FS LD YNP+ PEWR D+G V+ + L + T VP + ++ V PGLPT A+ Sbjct: 957 DQFQVMPLQFSKELDAYNPNTPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPTLAD 1016 Query: 1034 LFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVD 1093 L+VL P KRS ++++ + LN + F L+ GVRVLV A T Sbjct: 1017 LYVL-LPPPRPTRKRSLSSDKRLAAIQ-QVLNAQKISFLLRGGVRVLV-ALRDTGTGAEQ 1073 Query: 1094 LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKIPGINVYAQMQNEKEQEMISPVSHSE 1151 L A+++L + F++YKFKRK PG VYAQM NEKEQEM SPVSHSE Sbjct: 1074 LGGGGGYWAVVVLFVIGLFAAGAFILYKFKRKRPGRTVYAQMHNEKEQEMTSPVSHSE 1131 >gi|4507157 sortilin-related receptor containing LDLR class A repeats preproprotein [Homo sapiens] Length = 2214 Score = 254 bits (648), Expect = 4e-67 Identities = 184/668 (27%), Positives = 330/668 (49%), Gaps = 57/668 (8%) Query: 170 DSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGL--- 226 + +HNQ +VHW+G S+VI+ L + L S ++ S DYG +++K++DK+ Sbjct: 99 NDSHNQMVVHWAGEKSNVIVALAR-DSLALARPKSSDVYVSYDYGKSFKKISDKLNFGLG 157 Query: 227 ---KTILSYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQ 283 + +++ Y P + ++ + L I+ D T Q + + F LL H K Sbjct: 158 NRSEAVIAQFYHSPADNKRYIFAD--AYAQYLWITFDFCNTLQGFSIPFRAADLLLHSKA 215 Query: 284 EDWILAYSQ---DQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVD 340 + +L + + +++L+ S +FG+ W +IQE V F W + +K P+ +++E Sbjct: 216 SNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHV--KSFSWGIDPYDK-PNTIYIERHEPS 272 Query: 341 GHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVF----VQLTSGGRP---HYYVS 393 G+S R + ++ NQ + ++D Y+F V L + +VS Sbjct: 273 GYSTVF--RSTDFFQSRENQEVI-LEEVRDFQLRDKYMFATKVVHLLGSEQQSSVQLWVS 329 Query: 394 YRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLALE 453 + R + + ++ E+QVF V + N+ NLYIS+ G+ F+L+LE Sbjct: 330 FGRKPMRAAQFVTRHPINEYYIADASEDQVFVCVS--HSNNRTNLYISEAEGLKFSLSLE 387 Query: 454 NV--QSSRGPEGNIMI---------DLYEVAGIKGMFLAN----KKIDNQVKTFITYNKG 498 NV S G + ++ D + V G++G+++A + +++ IT++KG Sbjct: 388 NVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKG 447 Query: 499 RDWRLLQAPDTDLRGDPVHCLLPY-CSLHLHLKVSE--NPYTSGI-IASKDTAPSIIVAS 554 W LQAP G+ ++C L CSLHL ++S+ N + I SK++AP +I+A+ Sbjct: 448 GTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIAT 507 Query: 555 GNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSF 614 G++G L+ + ++++SS AG WR+ H + D GG++ A+ + L S Sbjct: 508 GSVGKNLA-SKTNVYISSSAGARWREALPGPHYYTWGDHGGIITAIAQ-GMETNELKYST 565 Query: 615 DEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG-HFSHRSEWQLVKVDYKSIFDRRC 673 +EG +W + F+ P+FV G+L EPGE++ + T+FG + + W +++V+ C Sbjct: 566 NEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIFGSNKENVHSWLILQVNATDALGVPC 625 Query: 674 AEEDYRPWQ-LHSQGEACIMGAKRIYKKRKSERKCMQGK-YAGAMESEPCVCTEADFDCD 731 E DY+ W +G C++G K ++K+R C G+ + + C CT D++CD Sbjct: 626 TENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECD 685 Query: 732 YGY---ERHSNGQCLPAFWFNPSSLSK--DCSLGQSYLNSTGYRKVVSNNCTDG-VREQY 785 +G+ E S C+P F+ S S C +G +Y + GYRK+ + C+ G V + Sbjct: 686 FGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGSTYRRTRGYRKISGDTCSGGDVEARL 745 Query: 786 TAKPQKCP 793 + CP Sbjct: 746 EGELVPCP 753 >gi|17149834 sortilin 1 preproprotein [Homo sapiens] Length = 831 Score = 226 bits (576), Expect = 1e-58 Identities = 169/678 (24%), Positives = 316/678 (46%), Gaps = 54/678 (7%) Query: 146 DPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLY-DYNLGSITE 204 + ++ R R +L + T D + W G ++ VIL+LT + + + + Sbjct: 82 EDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLVIMTFGQ 141 Query: 205 SSLWRSTDYGTTYEKLNDKVGLKTILSY--LYVCPTNKRKIMLLTDPEIESS---LLISS 259 S L+RS DYG ++ + D + I + + + P N K++L + S + SS Sbjct: 142 SKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSS 201 Query: 260 DEGATYQKYRLNFY-IQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNR- 317 D + + L F+ + +++ P+ D++LA S + L+ S FG +W+ I + V + Sbjct: 202 DFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKW 261 Query: 318 ------FYWSVMGSNKEPDLVHLEA-RTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDS 370 F+ + + + DL LE RT D + T ++ S Sbjct: 262 GSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIGVKIY----------------S 305 Query: 371 LIVQDHYVFVQLTSGG---RPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAV 427 + ++F + + R + + + + ++ +LP + +++ +++ VF V Sbjct: 306 FGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHV 365 Query: 428 QEWNQNDTYNLYISDTRGVYFTLALE-NVQSSRGPEGNIMIDLYEVAGIKGMFLANK-KI 485 E ++ SD RG+ ++ +L+ ++ ++ G E D V ++G+++ + Sbjct: 366 DEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGE----TDFTNVTSLRGVYITSVLSE 421 Query: 486 DNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIA--S 543 DN ++T IT+++G W L+ P+ D CSLH+H S + + +A S Sbjct: 422 DNSIQTMITFDQGGRWTHLRKPENS-ECDATAKNKNECSLHIHASYSISQKLNVPMAPLS 480 Query: 544 KDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHT 603 + A I++A G++G +S +++S D G +W ++ E H LD GG++VA++H+ Sbjct: 481 EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS 540 Query: 604 SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSH--RSEWQLV 661 S PI + S DEG+ W Y+FT P++ G+ EPG ++ ++++G S+W Sbjct: 541 SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY 600 Query: 662 KVDYKSIFDRRCAEEDYRPWQLHSQG-----EACIMGAKRIYKKRKSERKCMQGK-YAGA 715 +D+K I +R C E+DY W HS + CI+G K + + + C G+ Y Sbjct: 601 TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT 660 Query: 716 MESEPCVCTEADFDCDYGYERHSN-GQCLPAFWFNPSSLSKDCSLG-QSYLNSTGYRKVV 773 + C+C+ DF CD+GY R N +C+ L + C G + +L + GYRK+ Sbjct: 661 KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDL-EFCLYGREEHLTTNGYRKIP 719 Query: 774 SNNCTDGVREQYTAKPQK 791 + C GV K K Sbjct: 720 GDKCQGGVNPVREVKDLK 737 >gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo sapiens] Length = 384 Score = 41.6 bits (96), Expect = 0.005 Identities = 46/157 (29%), Positives = 61/157 (38%), Gaps = 15/157 (9%) Query: 28 APGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRP----------L 77 +P G +PHP S R A+ P + PGR+ + V P L Sbjct: 60 SPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPSQHQSGSRL 119 Query: 78 FSVAPGDR-ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGG 136 APG R S RA A+ AAR+ R + RG+G+ + R GG Sbjct: 120 RPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGG 179 Query: 137 QQEPGTRER---DPDKATR-FRMEELRLTSTTFALTG 169 Q P T R P ++ R FR L L S + TG Sbjct: 180 QPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTG 216 >gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo sapiens] Length = 384 Score = 41.6 bits (96), Expect = 0.005 Identities = 46/157 (29%), Positives = 61/157 (38%), Gaps = 15/157 (9%) Query: 28 APGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRP----------L 77 +P G +PHP S R A+ P + PGR+ + V P L Sbjct: 60 SPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPSQHQSGSRL 119 Query: 78 FSVAPGDR-ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGG 136 APG R S RA A+ AAR+ R + RG+G+ + R GG Sbjct: 120 RPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGG 179 Query: 137 QQEPGTRER---DPDKATR-FRMEELRLTSTTFALTG 169 Q P T R P ++ R FR L L S + TG Sbjct: 180 QPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTG 216 >gi|239508962 PREDICTED: hypothetical protein [Homo sapiens] Length = 384 Score = 41.6 bits (96), Expect = 0.005 Identities = 46/157 (29%), Positives = 61/157 (38%), Gaps = 15/157 (9%) Query: 28 APGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRP----------L 77 +P G +PHP S R A+ P + PGR+ + V P L Sbjct: 60 SPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPSQHQSGSRL 119 Query: 78 FSVAPGDR-ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGG 136 APG R S RA A+ AAR+ R + RG+G+ + R GG Sbjct: 120 RPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGG 179 Query: 137 QQEPGTRER---DPDKATR-FRMEELRLTSTTFALTG 169 Q P T R P ++ R FR L L S + TG Sbjct: 180 QPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTG 216 >gi|239754797 PREDICTED: hypothetical protein [Homo sapiens] Length = 170 Score = 40.0 bits (92), Expect = 0.013 Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 8/119 (6%) Query: 29 PGVCGGGSCCPSPHPSSA-PRSASTPRGF--SHQGRPGRAPATPLPLVVRPLFSVAPGDR 85 PGV G + + H S+A P + RG QG PG LP + R G R Sbjct: 3 PGVGVGAAGLGAAHRSTAAPGRGVSVRGTVGRQQGGPGHGNVDHLPNLGRQ--PRGAGSR 60 Query: 86 ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE--PGT 142 S RA TGA+ V +SG R + + + E GE +R R GG++E PGT Sbjct: 61 GASAPRAVRTGAAPEVVVQSGHRSHA-SKRRFLEEGEAPARRLSERRRGGGKEESRPGT 118 >gi|239749325 PREDICTED: hypothetical protein [Homo sapiens] Length = 155 Score = 40.0 bits (92), Expect = 0.013 Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 8/119 (6%) Query: 29 PGVCGGGSCCPSPHPSSA-PRSASTPRGF--SHQGRPGRAPATPLPLVVRPLFSVAPGDR 85 PGV G + + H S+A P + RG QG PG LP + R G R Sbjct: 3 PGVGVGAAGLGAAHRSTAAPGRGVSVRGTVGRQQGGPGHGNVDHLPNLGRQ--PRGAGSR 60 Query: 86 ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE--PGT 142 S RA TGA+ V +SG R + + + E GE +R R GG++E PGT Sbjct: 61 GASAPRAVRTGAAPEVVVQSGHRSHA-SKRRFLEEGEAPARRLSERRRGGGKEESRPGT 118 >gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo sapiens] Length = 209 Score = 40.0 bits (92), Expect = 0.013 Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 11/129 (8%) Query: 28 APGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRP----------L 77 +P G +PHP S R A+ P + PGR+ + V P L Sbjct: 60 SPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPSQHQSGSRL 119 Query: 78 FSVAPGDR-ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGG 136 APG R S RA A+ AAR+ R + RG+G+ + R GG Sbjct: 120 RPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGG 179 Query: 137 QQEPGTRER 145 Q P T R Sbjct: 180 QPPPLTCRR 188 >gi|239743415 PREDICTED: hypothetical protein [Homo sapiens] Length = 170 Score = 40.0 bits (92), Expect = 0.013 Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 8/119 (6%) Query: 29 PGVCGGGSCCPSPHPSSA-PRSASTPRGF--SHQGRPGRAPATPLPLVVRPLFSVAPGDR 85 PGV G + + H S+A P + RG QG PG LP + R G R Sbjct: 3 PGVGVGAAGLGAAHRSTAAPGRGVSVRGTVGRQQGGPGHGNVDHLPNLGRQ--PRGAGSR 60 Query: 86 ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE--PGT 142 S RA TGA+ V +SG R + + + E GE +R R GG++E PGT Sbjct: 61 GASAPRAVRTGAAPEVVVQSGHRSHA-SKRRFLEEGEAPARRLSERRRGGGKEESRPGT 118 >gi|239509122 PREDICTED: hypothetical protein [Homo sapiens] Length = 155 Score = 40.0 bits (92), Expect = 0.013 Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 8/119 (6%) Query: 29 PGVCGGGSCCPSPHPSSA-PRSASTPRGF--SHQGRPGRAPATPLPLVVRPLFSVAPGDR 85 PGV G + + H S+A P + RG QG PG LP + R G R Sbjct: 3 PGVGVGAAGLGAAHRSTAAPGRGVSVRGTVGRQQGGPGHGNVDHLPNLGRQ--PRGAGSR 60 Query: 86 ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE--PGT 142 S RA TGA+ V +SG R + + + E GE +R R GG++E PGT Sbjct: 61 GASAPRAVRTGAAPEVVVQSGHRSHA-SKRRFLEEGEAPARRLSERRRGGGKEESRPGT 118 >gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo sapiens] Length = 331 Score = 38.1 bits (87), Expect = 0.051 Identities = 43/143 (30%), Positives = 55/143 (38%), Gaps = 7/143 (4%) Query: 12 ARLSALLAGAGLLILCA-PGVCGGGSCCPSPH--PSSAPRSASTP-RGFSHQGRPGRAPA 67 A L ALL A L A PG + P P PSSAPR S+P F Q P PA Sbjct: 131 ASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPA 190 Query: 68 TPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRS 127 VRP PG R + G + A R R + ++ R EG R Sbjct: 191 PRAEAEVRPKI---PGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRK 247 Query: 128 PRGVLRDGGQQEPGTRERDPDKA 150 + + ++E +E P A Sbjct: 248 EKPRKEERPKKERPRKEERPRAA 270 >gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] Length = 389 Score = 35.8 bits (81), Expect = 0.25 Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 5/97 (5%) Query: 39 PSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGAS 98 P P P S P + R RP R P +VV LF V R ++ R G Sbjct: 177 PRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRR 236 Query: 99 MAVAARSGRRR-----RSGADQEKAERGEGASRSPRG 130 +A + GR A ++ G G SR PRG Sbjct: 237 PGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRG 273 >gi|41352718 deltex homolog 1 [Homo sapiens] Length = 620 Score = 35.8 bits (81), Expect = 0.25 Identities = 33/97 (34%), Positives = 38/97 (39%), Gaps = 14/97 (14%) Query: 5 GAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG---- 60 G G R SA GA L AP G P+P P + PRS P G G Sbjct: 240 GPPGALAVRPSATFTGAALW--AAPAA---GPAEPAPPPGAPPRSPGAPGGARTPGQNNL 294 Query: 61 -RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTG 96 RPG T V S+ PG AL ++ GTG Sbjct: 295 NRPGPQRTTS----VSARASIPPGVPALPVKNLNGTG 327 >gi|4503657 forkhead box H1 [Homo sapiens] Length = 365 Score = 35.4 bits (80), Expect = 0.33 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 1/49 (2%) Query: 34 GGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAP 82 GGS +P P AP+S+ P G + G P PLP RPL+ + P Sbjct: 174 GGSGEGAPWPGLAPQSSPVPAGTGNSGEEA-VPTPPLPSSERPLWPLCP 221 >gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens] Length = 461 Score = 35.4 bits (80), Expect = 0.33 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 11/90 (12%) Query: 48 RSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPG-----DRALSLERARGTGASMAVA 102 + A TP + G PG P +P V R + V+P + A + + A AVA Sbjct: 73 KEAKTP---TKNGLPGSRPGSPEREVKRKVEVVSPATPVPSETAPASVFPQNGAARRAVA 129 Query: 103 ARSGRRRRS---GADQEKAERGEGASRSPR 129 A+ GR+R+S G D++ + +G +PR Sbjct: 130 AQPGRKRKSNCLGTDEDSQDSSDGIPSAPR 159 >gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens] Length = 461 Score = 35.4 bits (80), Expect = 0.33 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 7/68 (10%) Query: 85 RALSLERARGTGA----SMAVAARSGRRRRSGADQE-KAERGEGASRSPRGVLRD--GGQ 137 R L L++ RG G S + + RRR GAD E +AE GE + R +LRD G+ Sbjct: 366 RLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGR 425 Query: 138 QEPGTRER 145 + G R+R Sbjct: 426 GQRGARQR 433 >gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens] Length = 1729 Score = 35.4 bits (80), Expect = 0.33 Identities = 34/112 (30%), Positives = 41/112 (36%), Gaps = 15/112 (13%) Query: 41 PHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMA 100 PHP A T S PGR PA P P G + L LE +S A Sbjct: 1421 PHP--ADPGMETGEALSFGASPGRCPARPPP----------SGSQGL-LEEMLAASSSKA 1467 Query: 101 VAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGTRERDPDKATR 152 VA R SG E G GA + VL G P R + +A++ Sbjct: 1468 VARRES--AASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQ 1517 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 35.0 bits (79), Expect = 0.43 Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 9/133 (6%) Query: 18 LAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPL 77 L G +L P GGG S P + + + R PA P+ L RP Sbjct: 512 LPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPG 571 Query: 78 FSVAPGDRALSLERA-------RGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRG 130 PG L E RG A + GRR R+G+D + G+ + RG Sbjct: 572 PVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRG 631 Query: 131 VLRDGGQQEPGTR 143 DG PG + Sbjct: 632 F--DGLAGLPGEK 642 >gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] Length = 227 Score = 35.0 bits (79), Expect = 0.43 Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 7/69 (10%) Query: 83 GDRALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGT 142 G LER GAS RS RRRRSG D G G +R+P GV Q T Sbjct: 3 GSAVTVLERG---GASSPAERRSKRRRRSGGD----GGGGGGARAPEGVRAPAAGQPRAT 55 Query: 143 RERDPDKAT 151 + P T Sbjct: 56 KGAPPPPGT 64 >gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] Length = 380 Score = 34.7 bits (78), Expect = 0.56 Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 17/104 (16%) Query: 39 PSPHPSSAPRSASTPRGF---SHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERARGT 95 P P P P P G +H G PA PLP P G Sbjct: 176 PPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGP--------------GGGGA 221 Query: 96 GASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE 139 GA AA +G + R + QE+A G A ++ G GG E Sbjct: 222 GAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGGLME 265 >gi|169204930 PREDICTED: hypothetical protein [Homo sapiens] Length = 373 Score = 34.7 bits (78), Expect = 0.56 Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 16/114 (14%) Query: 33 GGGSCCPSPH-----PSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRAL 87 GGG PSP PS PR T S + GRA + RP A Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP--------HAA 259 Query: 88 SLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPG 141 +RG GA+ +V+A + R R GA + R +G +R LR G PG Sbjct: 260 VRNSSRGRGAATSVSA-AARPTRGGARGHR--RADGRARGGCAQLRAGTPSAPG 310 >gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] Length = 373 Score = 34.7 bits (78), Expect = 0.56 Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 16/114 (14%) Query: 33 GGGSCCPSPH-----PSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRAL 87 GGG PSP PS PR T S + GRA + RP A Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP--------HAA 259 Query: 88 SLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPG 141 +RG GA+ +V+A + R R GA + R +G +R LR G PG Sbjct: 260 VRNSSRGRGAATSVSA-AARPTRGGARGHR--RADGRARGGCAQLRAGTPSAPG 310 >gi|169164783 PREDICTED: hypothetical protein [Homo sapiens] Length = 396 Score = 34.7 bits (78), Expect = 0.56 Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 9/116 (7%) Query: 30 GVCGG-GSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPG-DRAL 87 GV GG G P P + R H GR GR PL L+V P + G DR Sbjct: 71 GVGGGVGGAQPGSVPLGQHLALERGRTLGH-GRVGRRDPPPLGLLVNPRVAGVDGLDRGG 129 Query: 88 SLERAR-GTGASMAVAARSGRRRRSGADQ-----EKAERGEGASRSPRGVLRDGGQ 137 L+ A G + V +GR+RR+ Q + G G +R RG + GQ Sbjct: 130 RLDPAGIGQVLGLGVLGGAGRQRRALGGQALGLLAQVGIGAGHARGGRGAVGPAGQ 185 >gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] Length = 373 Score = 34.7 bits (78), Expect = 0.56 Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 16/114 (14%) Query: 33 GGGSCCPSPH-----PSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRAL 87 GGG PSP PS PR T S + GRA + RP A Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP--------HAA 259 Query: 88 SLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPG 141 +RG GA+ +V+A + R R GA + R +G +R LR G PG Sbjct: 260 VRNSSRGRGAATSVSA-AARPTRGGARGHR--RADGRARGGCAQLRAGTPSAPG 310 >gi|169163482 PREDICTED: hypothetical protein [Homo sapiens] Length = 396 Score = 34.7 bits (78), Expect = 0.56 Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 9/116 (7%) Query: 30 GVCGG-GSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPG-DRAL 87 GV GG G P P + R H GR GR PL L+V P + G DR Sbjct: 71 GVGGGVGGAQPGSVPLGQHLALERGRTLGH-GRVGRRDPPPLGLLVNPRVAGVDGLDRGG 129 Query: 88 SLERAR-GTGASMAVAARSGRRRRSGADQ-----EKAERGEGASRSPRGVLRDGGQ 137 L+ A G + V +GR+RR+ Q + G G +R RG + GQ Sbjct: 130 RLDPAGIGQVLGLGVLGGAGRQRRALGGQALGLLAQVGIGAGHARGGRGAVGPAGQ 185 >gi|5803080 macrophage receptor with collagenous structure [Homo sapiens] Length = 520 Score = 34.7 bits (78), Expect = 0.56 Identities = 35/157 (22%), Positives = 54/157 (34%), Gaps = 26/157 (16%) Query: 30 GVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRALSL 89 GV G P P SA +P G PG AT L Sbjct: 307 GVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGL------------------- 347 Query: 90 ERARGTGASMAVAARSGRRRRSGADQE---KAERGEGASRSPRGVLRDGGQQ-EPGTRER 145 +G+ + + GR+ SG K E+G P+G GQ+ + G + Sbjct: 348 ---KGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGS 404 Query: 146 DPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSG 182 ++ + E S + + G S +A V++SG Sbjct: 405 SGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSG 441 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,550,421 Number of Sequences: 37866 Number of extensions: 2319695 Number of successful extensions: 8326 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 134 Number of HSP's that attempted gapping in prelim test: 8096 Number of HSP's gapped (non-prelim): 328 length of query: 1198 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1084 effective length of database: 13,930,794 effective search space: 15100980696 effective search space used: 15100980696 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.