Guide to the Human Genome
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Search of human proteins with 13569919

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13569919 C1q and tumor necrosis factor related protein 3
isoform a [Homo sapiens]
         (246 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13569919 C1q and tumor necrosis factor related protein 3 isof...   531   e-151
gi|62739183 C1q and tumor necrosis factor related protein 3 isof...   469   e-133
gi|94818738 C1q and tumor necrosis factor related protein 2 [Hom...   110   9e-25
gi|58801559 complement component 1, q subcomponent-like 3 [Homo ...   109   2e-24
gi|154937344 complement component 1, q subcomponent-like 2 [Homo...   109   2e-24
gi|4757760 adiponectin precursor [Homo sapiens]                       108   3e-24
gi|5729785 complement component 1, q subcomponent-like 1 [Homo s...   108   4e-24
gi|13994280 C1q and tumor necrosis factor related protein 7 isof...   107   7e-24
gi|206597454 C1q and tumor necrosis factor related protein 7 iso...   107   7e-24
gi|206597452 C1q and tumor necrosis factor related protein 7 iso...   107   7e-24
gi|56606142 complement component 1, q subcomponent-like 4 [Homo ...   107   9e-24
gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]          105   3e-23
gi|50428931 C1q domain containing 1 isoform 3 [Homo sapiens]          105   3e-23
gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]          105   3e-23
gi|65301115 C1q and tumor necrosis factor related protein 9 [Hom...   105   5e-23
gi|56847616 C1q and tumor necrosis factor related protein 9B [Ho...   102   2e-22
gi|32967300 C1q and tumor necrosis factor related protein 6 [Hom...   100   9e-22
gi|32967294 C1q and tumor necrosis factor related protein 6 [Hom...   100   9e-22
gi|14149712 C1q and tumor necrosis factor related protein 5 prec...   100   2e-21
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           97   1e-20
gi|56786155 complement component 1, q subcomponent, C chain prec...    94   1e-19
gi|166235903 complement component 1, q subcomponent, C chain pre...    94   1e-19
gi|87298828 complement component 1, q subcomponent, B chain prec...    92   3e-19
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        91   9e-19
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        91   9e-19
gi|122937273 hypothetical protein LOC131149 [Homo sapiens]             89   3e-18
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                88   6e-18
gi|7705753 complement component 1, q subcomponent, A chain precu...    85   7e-17
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          80   2e-15
gi|38372917 C1q and tumor necrosis factor related protein 1 isof...    79   4e-15

>gi|13569919 C1q and tumor necrosis factor related protein 3 isoform
           a [Homo sapiens]
          Length = 246

 Score =  531 bits (1367), Expect = e-151
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MLWRQLIYWQLLALFFLPFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPG 60
           MLWRQLIYWQLLALFFLPFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPG
Sbjct: 1   MLWRQLIYWQLLALFFLPFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPG 60

Query: 61  PPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAF 120
           PPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAF
Sbjct: 61  PPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAF 120

Query: 121 MASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYV 180
           MASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYV
Sbjct: 121 MASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYV 180

Query: 181 YLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGF 240
           YLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGF
Sbjct: 181 YLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGF 240

Query: 241 LLFETK 246
           LLFETK
Sbjct: 241 LLFETK 246


>gi|62739183 C1q and tumor necrosis factor related protein 3 isoform
           b [Homo sapiens]
          Length = 319

 Score =  469 bits (1208), Expect = e-133
 Identities = 218/219 (99%), Positives = 219/219 (100%)

Query: 28  ESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKG 87
           +SPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKG
Sbjct: 101 QSPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKG 160

Query: 88  DKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNF 147
           DKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNF
Sbjct: 161 DKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNF 220

Query: 148 FDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNH 207
           FDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNH
Sbjct: 221 FDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNH 280

Query: 208 AVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK 246
           AVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK
Sbjct: 281 AVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK 319


>gi|94818738 C1q and tumor necrosis factor related protein 2 [Homo
           sapiens]
          Length = 330

 Score =  110 bits (276), Expect = 9e-25
 Identities = 66/205 (32%), Positives = 98/205 (47%), Gaps = 14/205 (6%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           RG  G  GPPG  G  G  G  G  GA G  G +G KG  G  G  G  G+ GPKG+KG 
Sbjct: 120 RGDSGEEGPPGRTGNRGKPGPKGKAGAIGRAGPRGPKGVNGTPGKHGTPGKKGPKGKKGE 179

Query: 110 PGIP-------PELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGV 162
           PG+P          + AF  ++   +  +   I F  +  N G  ++  +G+F   V G+
Sbjct: 180 PGLPGPCSCGSGHTKSAFSVAVTKSYPRERLPIKFDKILMNEGGHYNASSGKFVCGVPGI 239

Query: 163 YFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRM 222
           Y+FT+ +      + + + L+HNG      +     G  D +S   +L L +GDEVWL++
Sbjct: 240 YYFTYDITLAN--KHLAIGLVHNGQYRIRTFDAN-TGNHDVASGSTILALKQGDEVWLQI 296

Query: 223 ----GNGALHGDHQRFSTFAGFLLF 243
                NG  +  +   S F GFL++
Sbjct: 297 FYSEQNGLFYDPYWTDSLFTGFLIY 321


>gi|58801559 complement component 1, q subcomponent-like 3 [Homo
           sapiens]
          Length = 255

 Score =  109 bits (273), Expect = 2e-24
 Identities = 68/199 (34%), Positives = 100/199 (50%), Gaps = 17/199 (8%)

Query: 61  PPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAF 120
           P  I G  G  G  G  G  G  GE G  G +GP GE+G+ G +G  G PG  P L  A 
Sbjct: 56  PTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPMGPPGEKGEPGRQGLPGPPG-APGLNAAG 114

Query: 121 MASLATH-----------FSNQNSG---IIFSSVETNIGNFFDVMTGRFGAPVSGVYFFT 166
             S AT+              Q+ G   + F  V TN+GN +D  TG+F   + G+YFFT
Sbjct: 115 AISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFT 174

Query: 167 FS-MMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNG 225
           +  +M+  D   ++  L  N     S  + +     D +SN  VL L  GDEV++++  G
Sbjct: 175 YHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGG 234

Query: 226 ALH-GDHQRFSTFAGFLLF 243
             H G++ ++STF+GF+++
Sbjct: 235 KAHGGNNNKYSTFSGFIIY 253


>gi|154937344 complement component 1, q subcomponent-like 2 [Homo
           sapiens]
          Length = 287

 Score =  109 bits (272), Expect = 2e-24
 Identities = 71/211 (33%), Positives = 101/211 (47%), Gaps = 20/211 (9%)

Query: 53  QGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY--- 109
           QGP G PG PG PG  G  G  G  G  G  GEKGD G  G  G +   G     G    
Sbjct: 75  QGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTAGTASGVGVVGG 134

Query: 110 -PGIPPELQIAFMASLATHFSNQNSG--------------IIFSSVETNIGNFFDVMTGR 154
             G+  + +    ++L+  FS                   + F  V TN+GN +D  TG+
Sbjct: 135 GAGVGGDSEGEVTSALSATFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGK 194

Query: 155 FGAPVSGVYFFTFS-MMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLA 213
           F   V G+YFFT+  +M+  D   ++  L  NG    S  + +     D +SN  VL L 
Sbjct: 195 FSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLD 254

Query: 214 KGDEVWLRMGNGALH-GDHQRFSTFAGFLLF 243
            GDEV++++  G  H G++ ++STF+GFLL+
Sbjct: 255 SGDEVYVKLDGGKAHGGNNNKYSTFSGFLLY 285


>gi|4757760 adiponectin precursor [Homo sapiens]
          Length = 244

 Score =  108 bits (271), Expect = 3e-24
 Identities = 70/201 (34%), Positives = 104/201 (51%), Gaps = 19/201 (9%)

Query: 60  GPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPR---GERGQHGPKGEKGYPGI---- 112
           G PG PG++G  G +G  G  G KGEKGD G +GP+   GE G  G +G +G+PGI    
Sbjct: 42  GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101

Query: 113 --PPE----LQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFT 166
             P E     + AF   L T+ +  N  I F+ +  N  N +D  TG+F   + G+Y+F 
Sbjct: 102 GEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFA 161

Query: 167 FSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRM-GNG 225
           + +  +  +++V V L      +   Y    +   D +S   +L L  GD+VWL++ G G
Sbjct: 162 YHITVY--MKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEG 219

Query: 226 ---ALHGDHQRFSTFAGFLLF 243
               L+ D+   STF GFLL+
Sbjct: 220 ERNGLYADNDNDSTFTGFLLY 240


>gi|5729785 complement component 1, q subcomponent-like 1 [Homo
           sapiens]
          Length = 258

 Score =  108 bits (270), Expect = 4e-24
 Identities = 69/198 (34%), Positives = 101/198 (51%), Gaps = 14/198 (7%)

Query: 53  QGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRG--ERGQHGPKGEKGYP 110
           QGP G PG  G PG  G  G+ G  G  G  GEKG+ G  GP G    G  G      Y 
Sbjct: 66  QGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKGEPGKPGPPGLPGAGGSGAISTATYT 125

Query: 111 GIPPELQIAFMASLATHFSNQNSG---IIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTF 167
            +P   ++AF A L     N + G   + F  V TN+GN +D  +G+F   + G YFFT+
Sbjct: 126 TVP---RVAFYAGL----KNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTY 178

Query: 168 S-MMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGA 226
             +M+  D   ++  L  NG    S  + +     D +SN  +L L  GDEV++++  G 
Sbjct: 179 HVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGK 238

Query: 227 LH-GDHQRFSTFAGFLLF 243
            H G+  ++STF+GF+++
Sbjct: 239 AHGGNSNKYSTFSGFIIY 256


>gi|13994280 C1q and tumor necrosis factor related protein 7 isoform
           b [Homo sapiens]
          Length = 289

 Score =  107 bits (268), Expect = 7e-24
 Identities = 77/243 (31%), Positives = 107/243 (44%), Gaps = 50/243 (20%)

Query: 48  SFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEK--------------------- 86
           S  G  GPPGPPG  G PG HG  G  G  G +G KGEK                     
Sbjct: 35  SIPGLPGPPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEK 94

Query: 87  GD------KGDLGPRGERGQHGP---------KGEKGYPGIPP-------ELQIAFMASL 124
           GD      KG +GP GE+G+ GP         +GE+G PG+P         L+ AF   +
Sbjct: 95  GDQGETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGI 154

Query: 125 ATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMH 184
            T +  +   IIF+ V  N G  ++  TG+F     G+Y+F++ +      + + + L+H
Sbjct: 155 TTSYPEERLPIIFNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLAN--KHLAIGLVH 212

Query: 185 NGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRM----GNGALHGDHQRFSTFAGF 240
           NG      +     G  D +S   V+ L   DEVWL +     NG         S F+GF
Sbjct: 213 NGQYRIKTFDAN-TGNHDVASGSTVIYLQPEDEVWLEIFFTDQNGLFSDPGWADSLFSGF 271

Query: 241 LLF 243
           LL+
Sbjct: 272 LLY 274


>gi|206597454 C1q and tumor necrosis factor related protein 7
           isoform b [Homo sapiens]
          Length = 289

 Score =  107 bits (268), Expect = 7e-24
 Identities = 77/243 (31%), Positives = 107/243 (44%), Gaps = 50/243 (20%)

Query: 48  SFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEK--------------------- 86
           S  G  GPPGPPG  G PG HG  G  G  G +G KGEK                     
Sbjct: 35  SIPGLPGPPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEK 94

Query: 87  GD------KGDLGPRGERGQHGP---------KGEKGYPGIPP-------ELQIAFMASL 124
           GD      KG +GP GE+G+ GP         +GE+G PG+P         L+ AF   +
Sbjct: 95  GDQGETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGI 154

Query: 125 ATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMH 184
            T +  +   IIF+ V  N G  ++  TG+F     G+Y+F++ +      + + + L+H
Sbjct: 155 TTSYPEERLPIIFNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLAN--KHLAIGLVH 212

Query: 185 NGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRM----GNGALHGDHQRFSTFAGF 240
           NG      +     G  D +S   V+ L   DEVWL +     NG         S F+GF
Sbjct: 213 NGQYRIKTFDAN-TGNHDVASGSTVIYLQPEDEVWLEIFFTDQNGLFSDPGWADSLFSGF 271

Query: 241 LLF 243
           LL+
Sbjct: 272 LLY 274


>gi|206597452 C1q and tumor necrosis factor related protein 7
           isoform a [Homo sapiens]
          Length = 296

 Score =  107 bits (268), Expect = 7e-24
 Identities = 77/243 (31%), Positives = 107/243 (44%), Gaps = 50/243 (20%)

Query: 48  SFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEK--------------------- 86
           S  G  GPPGPPG  G PG HG  G  G  G +G KGEK                     
Sbjct: 42  SIPGLPGPPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEK 101

Query: 87  GD------KGDLGPRGERGQHGP---------KGEKGYPGIPP-------ELQIAFMASL 124
           GD      KG +GP GE+G+ GP         +GE+G PG+P         L+ AF   +
Sbjct: 102 GDQGETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGI 161

Query: 125 ATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMH 184
            T +  +   IIF+ V  N G  ++  TG+F     G+Y+F++ +      + + + L+H
Sbjct: 162 TTSYPEERLPIIFNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLAN--KHLAIGLVH 219

Query: 185 NGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRM----GNGALHGDHQRFSTFAGF 240
           NG      +     G  D +S   V+ L   DEVWL +     NG         S F+GF
Sbjct: 220 NGQYRIKTFDAN-TGNHDVASGSTVIYLQPEDEVWLEIFFTDQNGLFSDPGWADSLFSGF 278

Query: 241 LLF 243
           LL+
Sbjct: 279 LLY 281


>gi|56606142 complement component 1, q subcomponent-like 4 [Homo
           sapiens]
          Length = 238

 Score =  107 bits (267), Expect = 9e-24
 Identities = 68/201 (33%), Positives = 100/201 (49%), Gaps = 16/201 (7%)

Query: 54  GPPG-----PPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKG 108
           GP G     PP PPG  G  G  G  G  G  G  G +G  G+ G  G  G  GP    G
Sbjct: 41  GPDGAPASVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPGP----G 96

Query: 109 YPGIPPEL----QIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYF 164
             G+ P      +IAF A L          + F  V TN+GN ++  +G+F  P+ GVYF
Sbjct: 97  PGGVAPAAGYVPRIAFYAGLRRPHEGYEV-LRFDDVVTNVGNAYEAASGKFTCPMPGVYF 155

Query: 165 FTFS-MMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMG 223
           F +  +M+  D   ++  LM NG    S  + +     D +SN  +L L  GDEV++++ 
Sbjct: 156 FAYHVLMRGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLD 215

Query: 224 NGALHGDH-QRFSTFAGFLLF 243
            G +HG +  ++STF+GF+++
Sbjct: 216 GGKVHGGNTNKYSTFSGFIIY 236


>gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]
          Length = 1127

 Score =  105 bits (263), Expect = 3e-23
 Identities = 51/138 (36%), Positives = 87/138 (63%), Gaps = 3/138 (2%)

Query: 109  YPGIPPELQIAFMASLATHFS--NQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFT 166
            YP +P ++++AF A+  ++ +    +  I+F  +  N+G  FD+  GRF  PV+G Y F 
Sbjct: 990  YP-LPQQMRVAFSAARTSNLAPGTLDQPIVFDLLLNNLGETFDLQLGRFNCPVNGTYVFI 1048

Query: 167  FSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGA 226
            F M+K      +YV LM N   + S Y+ +     +T+SNHA+L+L +GD++WLR+  GA
Sbjct: 1049 FHMLKLAVNVPLYVNLMKNEEVLVSAYANDGAPDHETASNHAILQLFQGDQIWLRLHRGA 1108

Query: 227  LHGDHQRFSTFAGFLLFE 244
            ++G   ++STF+G+LL++
Sbjct: 1109 IYGSSWKYSTFSGYLLYQ 1126


>gi|50428931 C1q domain containing 1 isoform 3 [Homo sapiens]
          Length = 793

 Score =  105 bits (263), Expect = 3e-23
 Identities = 51/138 (36%), Positives = 87/138 (63%), Gaps = 3/138 (2%)

Query: 109 YPGIPPELQIAFMASLATHFS--NQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFT 166
           YP +P ++++AF A+  ++ +    +  I+F  +  N+G  FD+  GRF  PV+G Y F 
Sbjct: 656 YP-LPQQMRVAFSAARTSNLAPGTLDQPIVFDLLLNNLGETFDLQLGRFNCPVNGTYVFI 714

Query: 167 FSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGA 226
           F M+K      +YV LM N   + S Y+ +     +T+SNHA+L+L +GD++WLR+  GA
Sbjct: 715 FHMLKLAVNVPLYVNLMKNEEVLVSAYANDGAPDHETASNHAILQLFQGDQIWLRLHRGA 774

Query: 227 LHGDHQRFSTFAGFLLFE 244
           ++G   ++STF+G+LL++
Sbjct: 775 IYGSSWKYSTFSGYLLYQ 792


>gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]
          Length = 1077

 Score =  105 bits (263), Expect = 3e-23
 Identities = 51/138 (36%), Positives = 87/138 (63%), Gaps = 3/138 (2%)

Query: 109  YPGIPPELQIAFMASLATHFS--NQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFT 166
            YP +P ++++AF A+  ++ +    +  I+F  +  N+G  FD+  GRF  PV+G Y F 
Sbjct: 940  YP-LPQQMRVAFSAARTSNLAPGTLDQPIVFDLLLNNLGETFDLQLGRFNCPVNGTYVFI 998

Query: 167  FSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGA 226
            F M+K      +YV LM N   + S Y+ +     +T+SNHA+L+L +GD++WLR+  GA
Sbjct: 999  FHMLKLAVNVPLYVNLMKNEEVLVSAYANDGAPDHETASNHAILQLFQGDQIWLRLHRGA 1058

Query: 227  LHGDHQRFSTFAGFLLFE 244
            ++G   ++STF+G+LL++
Sbjct: 1059 IYGSSWKYSTFSGYLLYQ 1076


>gi|65301115 C1q and tumor necrosis factor related protein 9 [Homo
           sapiens]
          Length = 333

 Score =  105 bits (261), Expect = 5e-23
 Identities = 72/220 (32%), Positives = 102/220 (46%), Gaps = 10/220 (4%)

Query: 33  GGLPPDCSKCCHGDYSFRGYQGPPG---PPGPPGIPGNHGNNGNNGATGHEGAKGEKGDK 89
           G   P   K   GD    G +GP G   P GP G+PG  G  G  G  G  G  G +G+ 
Sbjct: 116 GETGPQGQKGNKGDVGPTGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEP 175

Query: 90  GDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFD 149
           G  G RG +G  G KG+ G   + P+       ++ + F + +  I F  +  N  N +D
Sbjct: 176 GVRGIRGWKGDRGEKGKIGETLVLPKSAFTVGLTVLSKFPSSDMPIKFDKILYNEFNHYD 235

Query: 150 VMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAV 209
              G+F   ++GVY+FT+ +        V V L+ NG  +       M  + D +S   V
Sbjct: 236 TAAGKFTCHIAGVYYFTYHITVFS--RNVQVSLVKNGVKILHTKDAYMSSE-DQASGGIV 292

Query: 210 LKLAKGDEVWLRMGNG----ALHGDHQRFSTFAGFLLFET 245
           L+L  GDEVWL++  G     L  D    +TF GFLLF +
Sbjct: 293 LQLKLGDEVWLQVTGGERFNGLFADEDDDTTFTGFLLFSS 332



 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 30/62 (48%), Positives = 35/62 (56%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           +G +G  G PG PG PG  G +G  G  G +G    KG KGD G RG  G+HGPKG  G 
Sbjct: 49  KGDKGDAGEPGRPGSPGKDGTSGEKGERGADGKVEAKGIKGDQGSRGSPGKHGPKGLAGP 108

Query: 110 PG 111
            G
Sbjct: 109 MG 110



 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 29/52 (55%), Positives = 34/52 (65%)

Query: 60  GPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPG 111
           G PGIPGN G+NG  G  G +GAKG+KGD G+ G  G  G+ G  GEKG  G
Sbjct: 26  GHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGRPGSPGKDGTSGEKGERG 77


>gi|56847616 C1q and tumor necrosis factor related protein 9B [Homo
           sapiens]
          Length = 333

 Score =  102 bits (255), Expect = 2e-22
 Identities = 70/221 (31%), Positives = 103/221 (46%), Gaps = 10/221 (4%)

Query: 33  GGLPPDCSKCCHGDYSFRGYQGPPG---PPGPPGIPGNHGNNGNNGATGHEGAKGEKGDK 89
           G   P   K   GD    G +GP G   P GP G+PG  G  G  G  G  G  G +G+ 
Sbjct: 116 GETGPQGQKGNKGDVGPTGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEP 175

Query: 90  GDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFD 149
           G  G RG +G  G KG+ G   + P+       ++ + F + +  I F  +  N  N +D
Sbjct: 176 GVRGIRGWKGDRGEKGKIGETLVLPKSAFTVGLTVLSKFPSSDVPIKFDKILYNEFNHYD 235

Query: 150 VMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAV 209
              G+F   ++GVY+FT+ +        V V L+ NG  +       +  + D +S   V
Sbjct: 236 TAVGKFTCHIAGVYYFTYHITVFS--RNVQVSLVKNGVKILHTRDAYVSSE-DQASGSIV 292

Query: 210 LKLAKGDEVWLRMGNG----ALHGDHQRFSTFAGFLLFETK 246
           L+L  GDE+WL++  G     L  D    +TF GFLLF ++
Sbjct: 293 LQLKLGDEMWLQVTGGERFNGLFADEDDDTTFTGFLLFSSQ 333



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 30/62 (48%), Positives = 35/62 (56%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           +G +G  G PG PG PG  G +G  G  G +G    KG KGD G RG  G+HGPKG  G 
Sbjct: 49  KGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKVEAKGIKGDQGSRGSPGKHGPKGLAGP 108

Query: 110 PG 111
            G
Sbjct: 109 MG 110



 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 29/52 (55%), Positives = 34/52 (65%)

Query: 60  GPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPG 111
           G PGIPGN G+NG  G  G +GAKG+KGD G+ G  G  G+ G  GEKG  G
Sbjct: 26  GHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERG 77


>gi|32967300 C1q and tumor necrosis factor related protein 6 [Homo
           sapiens]
          Length = 278

 Score =  100 bits (250), Expect = 9e-22
 Identities = 76/268 (28%), Positives = 112/268 (41%), Gaps = 57/268 (21%)

Query: 9   WQLLALFFLPFCLCQDEYMESPQTGGLPPDCSKCC--------------------HGDYS 48
           W  L LF L   +C+   +E      +   C +CC                    H    
Sbjct: 29  WAALLLFLL---MCEIPMVELTFDRAVASGCQRCCDSEDPLDPAHVSSASSSGRPHALPE 85

Query: 49  FRGY------QGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHG 102
            R Y      +G  G PGP G+PG  G  G  G  G +G+KG+                 
Sbjct: 86  IRPYINITILKGDKGDPGPMGLPGYMGREGPQGEPGPQGSKGD----------------- 128

Query: 103 PKGEKGYPGIPPELQ-IAFMA--SLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPV 159
            KGE G PG P + +  AF      A H       ++F  V  N+   FD+ TG+F AP+
Sbjct: 129 -KGEMGSPGAPCQKRFFAFSVGRKTALHSGEDFQTLLFERVFVNLDGCFDMATGQFAAPL 187

Query: 160 SGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVW 219
            G+YFF+ ++    + +E YV++MHN      +Y+ +   +S   S   +L LA GD VW
Sbjct: 188 RGIYFFSLNVHSW-NYKETYVHIMHNQKEAVILYA-QPSERSIMQSQSVMLDLAYGDRVW 245

Query: 220 LRM-----GNGALHGDHQRFSTFAGFLL 242
           +R+      N     D   + TF+G L+
Sbjct: 246 VRLFKRQRENAIYSNDFDTYITFSGHLI 273


>gi|32967294 C1q and tumor necrosis factor related protein 6 [Homo
           sapiens]
          Length = 278

 Score =  100 bits (250), Expect = 9e-22
 Identities = 76/268 (28%), Positives = 112/268 (41%), Gaps = 57/268 (21%)

Query: 9   WQLLALFFLPFCLCQDEYMESPQTGGLPPDCSKCC--------------------HGDYS 48
           W  L LF L   +C+   +E      +   C +CC                    H    
Sbjct: 29  WAALLLFLL---MCEIPMVELTFDRAVASGCQRCCDSEDPLDPAHVSSASSSGRPHALPE 85

Query: 49  FRGY------QGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHG 102
            R Y      +G  G PGP G+PG  G  G  G  G +G+KG+                 
Sbjct: 86  IRPYINITILKGDKGDPGPMGLPGYMGREGPQGEPGPQGSKGD----------------- 128

Query: 103 PKGEKGYPGIPPELQ-IAFMA--SLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPV 159
            KGE G PG P + +  AF      A H       ++F  V  N+   FD+ TG+F AP+
Sbjct: 129 -KGEMGSPGAPCQKRFFAFSVGRKTALHSGEDFQTLLFERVFVNLDGCFDMATGQFAAPL 187

Query: 160 SGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVW 219
            G+YFF+ ++    + +E YV++MHN      +Y+ +   +S   S   +L LA GD VW
Sbjct: 188 RGIYFFSLNVHSW-NYKETYVHIMHNQKEAVILYA-QPSERSIMQSQSVMLDLAYGDRVW 245

Query: 220 LRM-----GNGALHGDHQRFSTFAGFLL 242
           +R+      N     D   + TF+G L+
Sbjct: 246 VRLFKRQRENAIYSNDFDTYITFSGHLI 273


>gi|14149712 C1q and tumor necrosis factor related protein 5
           precursor [Homo sapiens]
          Length = 243

 Score =  100 bits (248), Expect = 2e-21
 Identities = 65/204 (31%), Positives = 100/204 (49%), Gaps = 14/204 (6%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGE------KGDKGDLGPRGERGQHGPK 104
           G  G PG  G  G+PG  G +G +GA G  G KGE       G +GD GPRGE G  GP 
Sbjct: 33  GLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGDPGPRGEAGPAGPT 92

Query: 105 GEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYF 164
           G  G   +PP    +   S +      ++ + F  V  N    +D +TG+F   V GVY+
Sbjct: 93  GPAGECSVPPRSAFSAKRSESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFTCQVPGVYY 152

Query: 165 FTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKG--KSDTSSNHAVLKLAKGDEVWLRM 222
           F      +     +   L+ NG ++ S + +   G  K  + S  A+++L   D+VW+++
Sbjct: 153 FAVHATVYR--ASLQFDLVKNGESIASFFQF-FGGWPKPASLSGGAMVRLEPEDQVWVQV 209

Query: 223 GNG---ALHGDHQRFSTFAGFLLF 243
           G G    ++   +  STF+GFL++
Sbjct: 210 GVGDYIGIYASIKTDSTFSGFLVY 233


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 71/231 (30%), Positives = 98/231 (42%), Gaps = 41/231 (17%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEG--AKGEKGDKGDLGPRGERGQHGPKGEKG 108
           G +GP GPPG PG PG+ G+ G+ G  G  G   KG  G  G  GP G RG  G  G  G
Sbjct: 449 GTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPG 508

Query: 109 YPGIP------------------PELQ----------------IAFMASLATHFSNQNSG 134
            PG P                  P L                  AF   L+  +    + 
Sbjct: 509 PPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTP 568

Query: 135 IIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYS 194
           I F  +  N    +D  TG F   + G+Y+F++ +  H     V+V L  NG  V   Y 
Sbjct: 569 IPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHV--HVKGTHVWVGLYKNGTPVMYTYD 626

Query: 195 YEMKGKSDTSSNHAVLKLAKGDEVWLRMGN---GALHGDHQRFSTFAGFLL 242
              KG  D +S  A++ L + D+VWL++ N     L+      S+F+GFL+
Sbjct: 627 EYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLV 677



 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 32/68 (47%), Positives = 39/68 (57%), Gaps = 4/68 (5%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
           G+    G QGP GP GPPG+    G  G NG  G  G KG++G  G++GP G  G  GP 
Sbjct: 200 GERGLPGPQGPTGPSGPPGV----GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPP 255

Query: 105 GEKGYPGI 112
           GE+G  GI
Sbjct: 256 GERGPEGI 263



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 31/62 (50%), Positives = 36/62 (58%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           +G QGP G PG PG+ G  GN G  G  G  G+ G  G KG+ GP G  G  G KGE+G 
Sbjct: 322 KGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGS 381

Query: 110 PG 111
           PG
Sbjct: 382 PG 383



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 31/63 (49%), Positives = 36/63 (57%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G QGP G PG  G+PG  G  G  G  G+ GAKGE+G  G  G  G  G+ G  G KG P
Sbjct: 344 GPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNP 403

Query: 111 GIP 113
           G+P
Sbjct: 404 GLP 406



 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 33/69 (47%), Positives = 37/69 (53%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G  GPPG PGP G  G  G  G+NG  G  GA G  G +G +GP G  G  G KG+ G P
Sbjct: 413 GVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSP 472

Query: 111 GIPPELQIA 119
           G P    IA
Sbjct: 473 GPPGPAGIA 481



 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 32/65 (49%), Positives = 34/65 (52%), Gaps = 1/65 (1%)

Query: 47  YSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGE 106
           Y   G QG PG PGPPG P   G  G  G  G  G +G  G KGD+GP G  G  GP G 
Sbjct: 85  YGSPGLQGEPGLPGPPG-PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGP 143

Query: 107 KGYPG 111
            G PG
Sbjct: 144 PGIPG 148



 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 32/63 (50%), Positives = 35/63 (55%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G +G PG PGP G PG  G  G  G  G  GAKG  G  G+ GPRG  G  G +G  G P
Sbjct: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPP 457

Query: 111 GIP 113
           GIP
Sbjct: 458 GIP 460



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 34/86 (39%), Positives = 40/86 (46%), Gaps = 3/86 (3%)

Query: 31  QTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKG 90
           +TG   P       G+    G  G PG PG PG+ G  GN G  G  G  G  G  G  G
Sbjct: 363 ETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPG 422

Query: 91  DLGPRGERGQHGPKGE---KGYPGIP 113
            +GP G +G  G  GE   +G PGIP
Sbjct: 423 PVGPAGAKGMPGHNGEAGPRGAPGIP 448



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 34/80 (42%), Positives = 41/80 (51%), Gaps = 16/80 (20%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGH--EGAKGEKGDKGDLGPR------------ 95
           RG QG PGPPGP G  G+ G +G  G  G+   G +GE G  G  GP             
Sbjct: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPG 115

Query: 96  --GERGQHGPKGEKGYPGIP 113
             GERG +GPKG+ G  G+P
Sbjct: 116 KPGERGPYGPKGDVGPAGLP 135



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 35/91 (38%), Positives = 42/91 (46%), Gaps = 26/91 (28%)

Query: 51  GYQGPPGPPG--PPGIPGNHGNNGNNGATGHEGAKGEKGDKG------------DLGPRG 96
           G  GPPGPPG   PG+PG  G  G  G  G  GAKGE+G  G            ++GP+G
Sbjct: 288 GIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQG 347

Query: 97  ERG------------QHGPKGEKGYPGIPPE 115
            +G            + GP G  GYPG   E
Sbjct: 348 PKGIPGSHGLPGPKGETGPAGPAGYPGAKGE 378



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 36/92 (39%), Positives = 43/92 (46%), Gaps = 9/92 (9%)

Query: 30  PQTGGLPPDCSKCCHGDYSFRGYQGPPGP---PGPPGIPGNHGNNGNNGATGHEGAKGEK 86
           P   G+P        G    +G  G PGP   PG  G PG  G NG  G  G+ GA G  
Sbjct: 141 PGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-GAPGRP 199

Query: 87  GDKGDLGPRGERGQHGP-----KGEKGYPGIP 113
           G++G  GP+G  G  GP     +GE G PG P
Sbjct: 200 GERGLPGPQGPTGPSGPPGVGKRGENGVPGQP 231



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/94 (36%), Positives = 40/94 (42%), Gaps = 15/94 (15%)

Query: 33  GGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGN---------------NGAT 77
           G + P   K   G +   G +G  GP GP G PG  G  G+               +G  
Sbjct: 341 GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPK 400

Query: 78  GHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPG 111
           G+ G  G KGD G  GP G  G  GP G KG PG
Sbjct: 401 GNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPG 434



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 33/88 (37%), Positives = 38/88 (43%), Gaps = 24/88 (27%)

Query: 50  RGYQGPPGPPGPPGI------------------PGNHGNNGNNGATGHEGAKGEKGDKGD 91
           +G +GP G PG PG                   PGN G  G  G  G  G  G KG+ G 
Sbjct: 307 KGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGP 366

Query: 92  LGP------RGERGQHGPKGEKGYPGIP 113
            GP      +GERG  G  G+ GYPG P
Sbjct: 367 AGPAGYPGAKGERGSPGSDGKPGYPGKP 394



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 34/83 (40%), Positives = 41/83 (49%), Gaps = 22/83 (26%)

Query: 51  GYQGPPGPPGP---------PGIPGNHGNNGNNG--ATGHEGAKGEKGDKGDLGP----- 94
           G QGP G PGP         PG+PG +G  G  G  A G  G +G  G +G  GP     
Sbjct: 159 GQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG 218

Query: 95  ---RGER---GQHGPKGEKGYPG 111
              RGE    GQ G KG++G+PG
Sbjct: 219 VGKRGENGVPGQPGIKGDRGFPG 241



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 34/88 (38%), Positives = 38/88 (43%), Gaps = 19/88 (21%)

Query: 45  GDYSFRGYQGPPGPPG-----------------PPGIPGNHGNNGNNGATGHEGAKGEKG 87
           G     G +GPPGPPG                 P G PG  G  G  GA G  G  G+KG
Sbjct: 130 GPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKG 189

Query: 88  DKGDLGP--RGERGQHGPKGEKGYPGIP 113
           + G   P   GERG  GP+G  G  G P
Sbjct: 190 EMGYGAPGRPGERGLPGPQGPTGPSGPP 217



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 39/107 (36%), Positives = 43/107 (40%), Gaps = 25/107 (23%)

Query: 34  GLPPDCSKCCHGDYSFRGYQGPP---------------------GPPGPPGIPGNHGNN- 71
           GLP        G     G  G P                     GPPGPPGIPG  G + 
Sbjct: 95  GLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISV 154

Query: 72  -GNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY--PGIPPE 115
            G  G  G  GA G +G  G+ G  G  G +G KGE GY  PG P E
Sbjct: 155 PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGE 201



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 36/97 (37%), Positives = 39/97 (40%), Gaps = 28/97 (28%)

Query: 45  GDYSFRGYQGPPGPPGP-----------------------PGIPGNHGNNGNNGATGHE- 80
           GD  F G  GP GPPGP                       PGIPG  G  G  G  G   
Sbjct: 235 GDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG 294

Query: 81  ----GAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIP 113
               G  G  G KG+ GP G  G  G KGE+G  G+P
Sbjct: 295 PPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP 331


>gi|56786155 complement component 1, q subcomponent, C chain
           precursor [Homo sapiens]
          Length = 245

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 69/217 (31%), Positives = 96/217 (44%), Gaps = 22/217 (10%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
           G Y   G  G PG PG  G  G  G  G  G     G +G KG KG+ G  G  G++GP 
Sbjct: 31  GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90

Query: 105 GEKGYPGIP----------------PELQIAFMASLATHF-SNQNSGIIFSSVETNIGNF 147
           G  G PG+P                 + Q  F  +  TH     NS I F++V TN    
Sbjct: 91  GPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGD 150

Query: 148 FDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNH 207
           +D  TG+F   V G+Y+F +          + V L  +G  V +   +  K  +  +S  
Sbjct: 151 YDTSTGKFTCKVPGLYYFVYHA---SHTANLCVLLYRSGVKVVTFCGHTSK-TNQVNSGG 206

Query: 208 AVLKLAKGDEVWLRMGN-GALHGDHQRFSTFAGFLLF 243
            +L+L  G+EVWL + +   + G     S F+GFLLF
Sbjct: 207 VLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGFLLF 243


>gi|166235903 complement component 1, q subcomponent, C chain
           precursor [Homo sapiens]
          Length = 245

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 69/217 (31%), Positives = 96/217 (44%), Gaps = 22/217 (10%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
           G Y   G  G PG PG  G  G  G  G  G     G +G KG KG+ G  G  G++GP 
Sbjct: 31  GCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPM 90

Query: 105 GEKGYPGIP----------------PELQIAFMASLATHF-SNQNSGIIFSSVETNIGNF 147
           G  G PG+P                 + Q  F  +  TH     NS I F++V TN    
Sbjct: 91  GPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGD 150

Query: 148 FDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNH 207
           +D  TG+F   V G+Y+F +          + V L  +G  V +   +  K  +  +S  
Sbjct: 151 YDTSTGKFTCKVPGLYYFVYHA---SHTANLCVLLYRSGVKVVTFCGHTSK-TNQVNSGG 206

Query: 208 AVLKLAKGDEVWLRMGN-GALHGDHQRFSTFAGFLLF 243
            +L+L  G+EVWL + +   + G     S F+GFLLF
Sbjct: 207 VLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGFLLF 243


>gi|87298828 complement component 1, q subcomponent, B chain
           precursor [Homo sapiens]
          Length = 253

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 71/213 (33%), Positives = 96/213 (45%), Gaps = 26/213 (12%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G  G PGP G PG PG  G  G  G  G  G  GEKGD G  G  G+ G  GP G KG P
Sbjct: 42  GIPGTPGPDGQPGTPGIKGEKGLPGLAGDHGEFGEKGDPGIPGNPGKVGPKGPMGPKGGP 101

Query: 111 GIP-------------PELQIAFMASLATHFS-NQNSGIIFSSVETNIGNFFDVMTGRFG 156
           G P                +IAF A+   +    ++  I F  V TN+ N ++  +G+F 
Sbjct: 102 GAPGAPGPKGESGDYKATQKIAFSATRTINVPLRRDQTIRFDHVITNMNNNYEPRSGKFT 161

Query: 157 APVSGVYFFTFSMMKHEDVEEVYVYLMHNGN-----TVFSMYSYEMKGKSDTSSNHAVLK 211
             V G+Y+FT+      +   + V LM           F  Y+Y        ++   VLK
Sbjct: 162 CKVPGLYYFTYHASSRGN---LCVNLMRGRERAQKVVTFCDYAY---NTFQVTTGGMVLK 215

Query: 212 LAKGDEVWLR-MGNGALHGDHQRFSTFAGFLLF 243
           L +G+ V+L+     +L G     S F+GFLLF
Sbjct: 216 LEQGENVFLQATDKNSLLGMEGANSIFSGFLLF 248


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 90.9 bits (224), Expect = 9e-19
 Identities = 78/261 (29%), Positives = 104/261 (39%), Gaps = 55/261 (21%)

Query: 34  GLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGA--------KGE 85
           G+P D  +   G     G  GP GP GPPGIPG  G  G  G  G  G          G 
Sbjct: 486 GIPGD--QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGP 543

Query: 86  KGDKGDLGPRGERGQHGPKGEKGYPGIP--------------PELQI------------- 118
            G  G LGP+G+ G  GP G  G PG P              P++ +             
Sbjct: 544 PGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGA 603

Query: 119 -------------AFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFF 165
                        AF A L   F    + + F+ +  N    ++  TG F   V GVY+F
Sbjct: 604 KKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYF 663

Query: 166 TFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGN- 224
            + +  H     V+V L  N   V   Y    KG  D +S  AVL L  GD V+L+M + 
Sbjct: 664 AYHV--HCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSE 721

Query: 225 --GALHGDHQRFSTFAGFLLF 243
               L+      S+F+G+LL+
Sbjct: 722 QAAGLYAGQYVHSSFSGYLLY 742



 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 38/90 (42%), Positives = 43/90 (47%), Gaps = 22/90 (24%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNH----------------------GNNGNNGATGHEGA 82
           G+   RG  GP GPPGPPG+PG+                       G  G  GA G  GA
Sbjct: 118 GEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGA 177

Query: 83  KGEKGDKGDLGPRGERGQHGPKGEKGYPGI 112
           KGE G KG++GP G  G  GP G  G PGI
Sbjct: 178 KGEIGQKGEIGPMGIPGPQGPPGPHGLPGI 207



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 33/66 (50%), Positives = 37/66 (56%), Gaps = 2/66 (3%)

Query: 50  RGYQGPPGPPGPPGIPG--NHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEK 107
           +G QG PG PGPPG+PG    G  G  G  G  G  G  G +G+ GP G  G  GP GE 
Sbjct: 333 KGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEP 392

Query: 108 GYPGIP 113
           G PGIP
Sbjct: 393 GLPGIP 398



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 35/84 (41%), Positives = 40/84 (47%), Gaps = 16/84 (19%)

Query: 45  GDYSFRGYQGPPGP-----------PGPPGIPGNHGNNGNNGATGHEGAKGEKGDK---- 89
           G     G QGPPGP           PG PG PG  G+ G  G  G +G +G KGDK    
Sbjct: 188 GPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGM 247

Query: 90  -GDLGPRGERGQHGPKGEKGYPGI 112
            G  G +G  G HGP G  G PG+
Sbjct: 248 PGAPGVKGPPGMHGPPGPVGLPGV 271



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 30/62 (48%), Positives = 34/62 (54%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G  GP GPPGP G PG  G  G  G  G  G  G +G  G +GP+GE GQ G  G  G P
Sbjct: 417 GIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP 476

Query: 111 GI 112
           G+
Sbjct: 477 GL 478



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 31/66 (46%), Positives = 36/66 (54%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G  G  GPPG PG+PG  G  G  GA G  G KGE G  G  GP G +G+ G +G  G P
Sbjct: 381 GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP 440

Query: 111 GIPPEL 116
           G   E+
Sbjct: 441 GFLGEV 446



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 38/100 (38%), Positives = 45/100 (45%), Gaps = 23/100 (23%)

Query: 29  SPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGD 88
           +P  GG P        G+    G  GP GPPG  G PG  G  G  G  G  G KGE G 
Sbjct: 382 APGIGGPP--------GEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGL 433

Query: 89  K---------GDLGPRGERGQHGP------KGEKGYPGIP 113
           +         G++GP G RG  GP       G+KG PG+P
Sbjct: 434 QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP 473



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 37/87 (42%), Positives = 41/87 (47%), Gaps = 18/87 (20%)

Query: 45  GDYSFRGYQGPPGP---------PGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGD---- 91
           G+    G QGPPGP         PG PG  G  G  G  G  G  G KGE G KG     
Sbjct: 414 GEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP 473

Query: 92  -----LGPRGERGQHGPKGEKGYPGIP 113
                LGP+GE G  G +G +G PGIP
Sbjct: 474 GVPGLLGPKGEPGIPGDQGLQGPPGIP 500



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 31/67 (46%), Positives = 37/67 (55%), Gaps = 3/67 (4%)

Query: 50  RGYQGPPGPPG---PPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGE 106
           RG +GP G PG   PPG PG  G  G  G  G  G  G KG+ G +GP+G  G  G  G 
Sbjct: 374 RGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGL 433

Query: 107 KGYPGIP 113
           +G+PG P
Sbjct: 434 QGFPGKP 440



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 35/76 (46%), Positives = 41/76 (53%), Gaps = 10/76 (13%)

Query: 51  GYQGP---PGPPGPPGIPG--NHGNNGNNGATGHEGAKGEKGDKGDLGPRG-----ERGQ 100
           G QGP   PG  GPPGIPG    G +G  G  G  G KGE+G  G  GP G     + G 
Sbjct: 296 GPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF 355

Query: 101 HGPKGEKGYPGIPPEL 116
            GPKG++G  G+P  L
Sbjct: 356 PGPKGDRGMGGVPGAL 371



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 30/63 (47%), Positives = 33/63 (52%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G +G PG PG PG+ G  G  G  G  G +G  G  G  G  GP G  G  GPKGE G P
Sbjct: 465 GQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLP 524

Query: 111 GIP 113
           G P
Sbjct: 525 GPP 527



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 32/78 (41%), Positives = 36/78 (46%), Gaps = 9/78 (11%)

Query: 45  GDYSFRGYQGPPGP---------PGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPR 95
           G    RG  GP GP         PG PG+PG  G  G  G  G +G +G  G  G  GP 
Sbjct: 447 GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506

Query: 96  GERGQHGPKGEKGYPGIP 113
           G  G  G  G KG PG+P
Sbjct: 507 GPIGPPGIPGPKGEPGLP 524



 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 4/65 (6%)

Query: 51  GYQGPPG---PPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEK 107
           G +GPPG   PPGP G+PG  G  G  G  G +G  G+ G  G+ GP+G  G  G +G  
Sbjct: 252 GVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP 310

Query: 108 GYPGI 112
           G PGI
Sbjct: 311 GIPGI 315



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 29/65 (44%), Positives = 34/65 (52%), Gaps = 2/65 (3%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEK--GDKGDLGPRGERGQHGPKGEKG 108
           G+ GP GP G PG PG  G  G  G  G +G  G    G  G  G  G+ G  G KGE+G
Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQG 337

Query: 109 YPGIP 113
            PG+P
Sbjct: 338 LPGLP 342



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 28/64 (43%), Positives = 33/64 (51%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           +G  G  GP GPPG  G  G  G  G  G  G  G  G +G  GP G +G+ G KG  G 
Sbjct: 413 KGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGL 472

Query: 110 PGIP 113
           PG+P
Sbjct: 473 PGVP 476



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 37/87 (42%), Positives = 40/87 (45%), Gaps = 7/87 (8%)

Query: 30  PQTGGLP-PDCSKCCHGDYSFRGYQGPPG---PPGPPGIPGNHGNNGNNGATGHEGAKGE 85
           P   GLP P   K   G     G  G PG   P G PGIPG+ G  G  G  G  G  G 
Sbjct: 449 PGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGP 508

Query: 86  KGDKGDLGPRGERGQHGPKGEKGYPGI 112
            G  G  GP+GE G  GP    G+PGI
Sbjct: 509 IGPPGIPGPKGEPGLPGP---PGFPGI 532



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/65 (44%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGER---GQHGPKGEK 107
           G  GP G  GP G PG  G  G  G  G  G  G  G  G  GP+GE    G  GP G K
Sbjct: 369 GALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK 428

Query: 108 GYPGI 112
           G PG+
Sbjct: 429 GEPGL 433



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 89  KGDLGPRGERGQHGPKGEKGYPG 111
           +G+ GPRGE G  GP G  G PG
Sbjct: 117 RGEQGPRGEPGPRGPPGPPGLPG 139


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 90.9 bits (224), Expect = 9e-19
 Identities = 78/261 (29%), Positives = 104/261 (39%), Gaps = 55/261 (21%)

Query: 34  GLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGA--------KGE 85
           G+P D  +   G     G  GP GP GPPGIPG  G  G  G  G  G          G 
Sbjct: 486 GIPGD--QGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGP 543

Query: 86  KGDKGDLGPRGERGQHGPKGEKGYPGIP--------------PELQI------------- 118
            G  G LGP+G+ G  GP G  G PG P              P++ +             
Sbjct: 544 PGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGA 603

Query: 119 -------------AFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFF 165
                        AF A L   F    + + F+ +  N    ++  TG F   V GVY+F
Sbjct: 604 KKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYF 663

Query: 166 TFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGN- 224
            + +  H     V+V L  N   V   Y    KG  D +S  AVL L  GD V+L+M + 
Sbjct: 664 AYHV--HCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSE 721

Query: 225 --GALHGDHQRFSTFAGFLLF 243
               L+      S+F+G+LL+
Sbjct: 722 QAAGLYAGQYVHSSFSGYLLY 742



 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 38/90 (42%), Positives = 43/90 (47%), Gaps = 22/90 (24%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNH----------------------GNNGNNGATGHEGA 82
           G+   RG  GP GPPGPPG+PG+                       G  G  GA G  GA
Sbjct: 118 GEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGA 177

Query: 83  KGEKGDKGDLGPRGERGQHGPKGEKGYPGI 112
           KGE G KG++GP G  G  GP G  G PGI
Sbjct: 178 KGEIGQKGEIGPMGIPGPQGPPGPHGLPGI 207



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 33/66 (50%), Positives = 37/66 (56%), Gaps = 2/66 (3%)

Query: 50  RGYQGPPGPPGPPGIPG--NHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEK 107
           +G QG PG PGPPG+PG    G  G  G  G  G  G  G +G+ GP G  G  GP GE 
Sbjct: 333 KGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEP 392

Query: 108 GYPGIP 113
           G PGIP
Sbjct: 393 GLPGIP 398



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 35/84 (41%), Positives = 40/84 (47%), Gaps = 16/84 (19%)

Query: 45  GDYSFRGYQGPPGP-----------PGPPGIPGNHGNNGNNGATGHEGAKGEKGDK---- 89
           G     G QGPPGP           PG PG PG  G+ G  G  G +G +G KGDK    
Sbjct: 188 GPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGM 247

Query: 90  -GDLGPRGERGQHGPKGEKGYPGI 112
            G  G +G  G HGP G  G PG+
Sbjct: 248 PGAPGVKGPPGMHGPPGPVGLPGV 271



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 30/62 (48%), Positives = 34/62 (54%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G  GP GPPGP G PG  G  G  G  G  G  G +G  G +GP+GE GQ G  G  G P
Sbjct: 417 GIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP 476

Query: 111 GI 112
           G+
Sbjct: 477 GL 478



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 31/66 (46%), Positives = 36/66 (54%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G  G  GPPG PG+PG  G  G  GA G  G KGE G  G  GP G +G+ G +G  G P
Sbjct: 381 GAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKP 440

Query: 111 GIPPEL 116
           G   E+
Sbjct: 441 GFLGEV 446



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 38/100 (38%), Positives = 45/100 (45%), Gaps = 23/100 (23%)

Query: 29  SPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGD 88
           +P  GG P        G+    G  GP GPPG  G PG  G  G  G  G  G KGE G 
Sbjct: 382 APGIGGPP--------GEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGL 433

Query: 89  K---------GDLGPRGERGQHGP------KGEKGYPGIP 113
           +         G++GP G RG  GP       G+KG PG+P
Sbjct: 434 QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP 473



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 37/87 (42%), Positives = 41/87 (47%), Gaps = 18/87 (20%)

Query: 45  GDYSFRGYQGPPGP---------PGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGD---- 91
           G+    G QGPPGP         PG PG  G  G  G  G  G  G KGE G KG     
Sbjct: 414 GEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLP 473

Query: 92  -----LGPRGERGQHGPKGEKGYPGIP 113
                LGP+GE G  G +G +G PGIP
Sbjct: 474 GVPGLLGPKGEPGIPGDQGLQGPPGIP 500



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 31/67 (46%), Positives = 37/67 (55%), Gaps = 3/67 (4%)

Query: 50  RGYQGPPGPPG---PPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGE 106
           RG +GP G PG   PPG PG  G  G  G  G  G  G KG+ G +GP+G  G  G  G 
Sbjct: 374 RGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGL 433

Query: 107 KGYPGIP 113
           +G+PG P
Sbjct: 434 QGFPGKP 440



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 35/76 (46%), Positives = 41/76 (53%), Gaps = 10/76 (13%)

Query: 51  GYQGP---PGPPGPPGIPG--NHGNNGNNGATGHEGAKGEKGDKGDLGPRG-----ERGQ 100
           G QGP   PG  GPPGIPG    G +G  G  G  G KGE+G  G  GP G     + G 
Sbjct: 296 GPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF 355

Query: 101 HGPKGEKGYPGIPPEL 116
            GPKG++G  G+P  L
Sbjct: 356 PGPKGDRGMGGVPGAL 371



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 30/63 (47%), Positives = 33/63 (52%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G +G PG PG PG+ G  G  G  G  G +G  G  G  G  GP G  G  GPKGE G P
Sbjct: 465 GQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLP 524

Query: 111 GIP 113
           G P
Sbjct: 525 GPP 527



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 32/78 (41%), Positives = 36/78 (46%), Gaps = 9/78 (11%)

Query: 45  GDYSFRGYQGPPGP---------PGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPR 95
           G    RG  GP GP         PG PG+PG  G  G  G  G +G +G  G  G  GP 
Sbjct: 447 GPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPS 506

Query: 96  GERGQHGPKGEKGYPGIP 113
           G  G  G  G KG PG+P
Sbjct: 507 GPIGPPGIPGPKGEPGLP 524



 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 4/65 (6%)

Query: 51  GYQGPPG---PPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEK 107
           G +GPPG   PPGP G+PG  G  G  G  G +G  G+ G  G+ GP+G  G  G +G  
Sbjct: 252 GVKGPPGMHGPPGPVGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP 310

Query: 108 GYPGI 112
           G PGI
Sbjct: 311 GIPGI 315



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 29/65 (44%), Positives = 34/65 (52%), Gaps = 2/65 (3%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEK--GDKGDLGPRGERGQHGPKGEKG 108
           G+ GP GP G PG PG  G  G  G  G +G  G    G  G  G  G+ G  G KGE+G
Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQG 337

Query: 109 YPGIP 113
            PG+P
Sbjct: 338 LPGLP 342



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 28/64 (43%), Positives = 33/64 (51%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           +G  G  GP GPPG  G  G  G  G  G  G  G  G +G  GP G +G+ G KG  G 
Sbjct: 413 KGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGL 472

Query: 110 PGIP 113
           PG+P
Sbjct: 473 PGVP 476



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 37/87 (42%), Positives = 40/87 (45%), Gaps = 7/87 (8%)

Query: 30  PQTGGLP-PDCSKCCHGDYSFRGYQGPPG---PPGPPGIPGNHGNNGNNGATGHEGAKGE 85
           P   GLP P   K   G     G  G PG   P G PGIPG+ G  G  G  G  G  G 
Sbjct: 449 PGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGP 508

Query: 86  KGDKGDLGPRGERGQHGPKGEKGYPGI 112
            G  G  GP+GE G  GP    G+PGI
Sbjct: 509 IGPPGIPGPKGEPGLPGP---PGFPGI 532



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/65 (44%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGER---GQHGPKGEK 107
           G  GP G  GP G PG  G  G  G  G  G  G  G  G  GP+GE    G  GP G K
Sbjct: 369 GALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPK 428

Query: 108 GYPGI 112
           G PG+
Sbjct: 429 GEPGL 433



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 89  KGDLGPRGERGQHGPKGEKGYPG 111
           +G+ GPRGE G  GP G  G PG
Sbjct: 117 RGEQGPRGEPGPRGPPGPPGLPG 139


>gi|122937273 hypothetical protein LOC131149 [Homo sapiens]
          Length = 477

 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 68/230 (29%), Positives = 99/230 (43%), Gaps = 29/230 (12%)

Query: 41  KCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGD------KGDLGP 94
           K C GD   RG +G  G  G  G  G+ G++G  G +G  G  G KGD      KG+LGP
Sbjct: 241 KGCCGDSGERGGKGQKGEGGMKGEKGSKGDSGMEGKSGRNGLPGAKGDPGIKGEKGELGP 300

Query: 95  ---------------RGERGQHGPKGEKGYPGIPPEL----QIAFMASLATHFSNQNSGI 135
                          +G RG  G KG +G+ G   EL    + AF A L+  F   N  I
Sbjct: 301 PGLLGPTGPKGDIGNKGVRGPTGKKGSRGFKGSKGELARVPRSAFSAGLSKPFPPPNIPI 360

Query: 136 IFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSY 195
            F  +  N    +  +TG+F   + G Y F++ +          + L+      F     
Sbjct: 361 KFEKILYNDQGNYSPVTGKFNCSIPGTYVFSYHITVRG--RPARISLVAQNKKQFKSRET 418

Query: 196 EMKGKSDTSSNHAVLKLAKGDEVWLRMGN--GALHGDHQRFSTFAGFLLF 243
               + D +S   +LKL+ GD+VWL +      ++   +  S F GFLL+
Sbjct: 419 LYGQEIDQASLLVILKLSAGDQVWLEVSKDWNGVYVSAEDDSIFTGFLLY 468



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 33/73 (45%), Positives = 38/73 (52%), Gaps = 6/73 (8%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGE------KGDKGDLGPRGER 98
           GD    GY G PG  G PG  G+ GN G  G  G +G+KG+      KG+KGD G  G  
Sbjct: 158 GDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSP 217

Query: 99  GQHGPKGEKGYPG 111
           G HG  G KG  G
Sbjct: 218 GLHGGPGAKGEKG 230



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 12/87 (13%)

Query: 38  DCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGE 97
           +C  CC      +G  G  G PGP G  GN G  G  G  G +G +G KG+KG  G RG+
Sbjct: 100 NCCDCCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGD 159

Query: 98  ------------RGQHGPKGEKGYPGI 112
                       +G+ GPKG+KG  G+
Sbjct: 160 QGVPGYPGKPGAQGEPGPKGDKGNIGL 186



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 29/63 (46%), Positives = 35/63 (55%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           RG QG PG PG PG  G  G  G+ G  G  G KG+KG KGD      +G+ G +G  G 
Sbjct: 157 RGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGS 216

Query: 110 PGI 112
           PG+
Sbjct: 217 PGL 219



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 28/58 (48%), Positives = 31/58 (53%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKG 108
           G QGP G  G  G+ G  G+ G  G  G  GA+GE G KGD G  G  G  G KG KG
Sbjct: 140 GPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKG 197



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 35/98 (35%), Positives = 40/98 (40%), Gaps = 5/98 (5%)

Query: 15  FFLPFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNN 74
           FFL  C C       P   G P +  +   G     G  G PGPPG  G  G  G  G  
Sbjct: 97  FFLNCCDCCSPV---PGQKGEPGETGQ--PGPKGEAGNLGIPGPPGVVGPQGPRGYKGEK 151

Query: 75  GATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGI 112
           G  G  G +G  G  G  G +GE G  G KG  G  G+
Sbjct: 152 GLKGERGDQGVPGYPGKPGAQGEPGPKGDKGNIGLGGV 189


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 72/221 (32%), Positives = 99/221 (44%), Gaps = 13/221 (5%)

Query: 34  GLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKG--- 90
           GLP    +   G+    G  GPPG PG PGI G  G  G  G  G  GA  E G  G   
Sbjct: 487 GLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHL 546

Query: 91  -DLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFD 149
            + G  G     G K + G   +      AF A L + F      + F     N  + ++
Sbjct: 547 PNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYN 606

Query: 150 VMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYE--MKGKSDTSSNH 207
             TG F  PV GVY+F +    H  V+   V++    N V + Y+Y+   KG  D +S  
Sbjct: 607 PATGIFTCPVGGVYYFAY----HVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGG 662

Query: 208 AVLKLAKGDEVWLRMGN---GALHGDHQRFSTFAGFLLFET 245
           AVL+L   D+VW++M +     L+      S+F+GFLL  T
Sbjct: 663 AVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT 703



 Score = 64.3 bits (155), Expect = 9e-11
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 33  GGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNH-----GNNGNNGATGHEGAKGEKG 87
           G + P       G+   RG QG  GPPGPPG+PG       G  G  G  G  G +GE G
Sbjct: 132 GKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPG 191

Query: 88  DKGDLGPRGERGQHGPKGEKGYPGIP 113
            +G+ GP G+RG  G  G  G PG+P
Sbjct: 192 PQGEPGPPGDRGLKGDNG-VGQPGLP 216



 Score = 64.3 bits (155), Expect = 9e-11
 Identities = 38/92 (41%), Positives = 45/92 (48%), Gaps = 13/92 (14%)

Query: 28  ESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPG------PPGIPGNHGNNGNNGATGHEG 81
           + PQ  G PP       G     G +GPPGP G      PPG+PG  G+ G +G  G  G
Sbjct: 351 QGPQGLGGPPGLP----GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPG 406

Query: 82  AKGEKGDKGDLGPRGERGQHGPKGEKGYPGIP 113
             GE+G  G  GP G     GPKGE G+ G P
Sbjct: 407 VPGERGLPGAHGPPGPT---GPKGEPGFTGRP 435



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 30/67 (44%), Positives = 36/67 (53%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
           G+   +G  GPPG PG  G+PG  G  G  G  G  G  G  G +GD GP G  G+ G  
Sbjct: 349 GEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVP 408

Query: 105 GEKGYPG 111
           GE+G PG
Sbjct: 409 GERGLPG 415



 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 33/70 (47%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPG--NHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHG 102
           G     G  G  G PGPPG+PG    G  G +G  G  G KGE G  G  GPRGE G  G
Sbjct: 211 GQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVG 270

Query: 103 PKGEKGYPGI 112
           PKG  G  G+
Sbjct: 271 PKGPPGVDGV 280



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 32/65 (49%), Positives = 35/65 (53%), Gaps = 3/65 (4%)

Query: 51  GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
           G QGP G  GPPG+PG+ G  G  G  G    KGE G  G  G  G RG  GP G  G P
Sbjct: 349 GEQGPQGLGGPPGLPGSAGLPGRRGPPG---PKGEAGPGGPPGVPGIRGDQGPSGLAGKP 405

Query: 111 GIPPE 115
           G+P E
Sbjct: 406 GVPGE 410



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 31/64 (48%), Positives = 34/64 (53%)

Query: 50  RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           RG QGP G  G PG+PG  G  G +G  G  G KGE G  G  G  G  G  G KG+ G 
Sbjct: 393 RGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGL 452

Query: 110 PGIP 113
           PG P
Sbjct: 453 PGQP 456



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 33/83 (39%), Positives = 41/83 (49%), Gaps = 5/83 (6%)

Query: 30  PQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDK 89
           P + GLP        G    +G  GP GPPG PGI G+ G +G  G  G  G +G  G  
Sbjct: 363 PGSAGLPGR-----RGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAH 417

Query: 90  GDLGPRGERGQHGPKGEKGYPGI 112
           G  GP G +G+ G  G  G PG+
Sbjct: 418 GPPGPTGPKGEPGFTGRPGGPGV 440



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 34/86 (39%), Positives = 38/86 (44%), Gaps = 15/86 (17%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGE---------------KGDK 89
           G+    G  GPPGP GP G PG  G  G  G  G  G KG+                G +
Sbjct: 409 GERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQ 468

Query: 90  GDLGPRGERGQHGPKGEKGYPGIPPE 115
           G  GP G +G  G KGE G PG P E
Sbjct: 469 GPAGPIGPQGLPGLKGEPGLPGPPGE 494



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 35/88 (39%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 30  PQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAK---GEK 86
           P T G P       +G     G +G  GP G PG+ G+ G  G +G  G +G +   G  
Sbjct: 301 PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP 360

Query: 87  GDKGDLGPRGERGQHGPKGEKGYPGIPP 114
           G  G  G  G RG  GPKGE G PG PP
Sbjct: 361 GLPGSAGLPGRRGPPGPKGEAG-PGGPP 387



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 42/115 (36%), Positives = 49/115 (42%), Gaps = 24/115 (20%)

Query: 18  PFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGN--------HG 69
           PF   + +Y+E P    LP D      G+    G  GP GPPGPPG PG         HG
Sbjct: 55  PFREGKGQYLEMPLPL-LPMDLK----GEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHG 109

Query: 70  NNG--------NNGATGHEGAKGEKGDKGDLGPRGE---RGQHGPKGEKGYPGIP 113
             G          G  G  G  G+ G  G  G RGE   RG  G +G  G PG+P
Sbjct: 110 QPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLP 164



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 30/71 (42%), Positives = 38/71 (53%), Gaps = 7/71 (9%)

Query: 50  RGYQGPPGPPGPPGI-----PGNHGNNGNNGATGHEGAKGEKGDKGDLGPR--GERGQHG 102
           RG  G  GP GPPG+     PG  G  G  G +G +G  G +G  G +GP   G  G  G
Sbjct: 263 RGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPG 322

Query: 103 PKGEKGYPGIP 113
           PKG++G  G+P
Sbjct: 323 PKGDRGPAGVP 333



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 31/76 (40%), Positives = 33/76 (43%), Gaps = 9/76 (11%)

Query: 45  GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGH---------EGAKGEKGDKGDLGPR 95
           GD    G  G PG PG  G+PG HG  G  G  G           G  G  G KGDLG  
Sbjct: 394 GDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLP 453

Query: 96  GERGQHGPKGEKGYPG 111
           G+ G  GP G  G  G
Sbjct: 454 GQPGLRGPSGIPGLQG 469


>gi|7705753 complement component 1, q subcomponent, A chain
           precursor [Homo sapiens]
          Length = 245

 Score = 84.7 bits (208), Expect = 7e-17
 Identities = 62/198 (31%), Positives = 93/198 (46%), Gaps = 6/198 (3%)

Query: 51  GYQGPPGPPGPPGI-PGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
           G +G  G PG PGI  G  G  G+ G  G  G  G+ G  G  GP G RG  G KG KG 
Sbjct: 46  GLKGEQGEPGAPGIRTGIQGLKGDQGEPGPSGNPGKVGYPGPSGPLGARGIPGIKGTKGS 105

Query: 110 PGIPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSM 169
           PG   +      +++  +     + +IF +V TN    +   +GRF   V G Y+FTF +
Sbjct: 106 PGNIKDQPRPAFSAIRRNPPMGGNVVIFDTVITNQEEPYQNHSGRFVCTVPGYYYFTFQV 165

Query: 170 MKHEDVEEVYVYLMHNGNTVFSMYSYEM--KGKSDTSSNHAVLKLAKGDEVWLRMG--NG 225
           +   ++  + +     G    S+   +   KG     S   VL+L +GD+VW+      G
Sbjct: 166 LSQWEI-CLSIVSSSRGQVRRSLGFCDTTNKGLFQVVSGGMVLQLQQGDQVWVEKDPKKG 224

Query: 226 ALHGDHQRFSTFAGFLLF 243
            ++   +  S F+GFL+F
Sbjct: 225 HIYQGSEADSVFSGFLIF 242



 Score = 34.7 bits (78), Expect = 0.078
 Identities = 15/27 (55%), Positives = 18/27 (66%)

Query: 87  GDKGDLGPRGERGQHGPKGEKGYPGIP 113
           G KG+ G  G RG+ G KGE+G PG P
Sbjct: 31  GKKGEAGRPGRRGRPGLKGEQGEPGAP 57



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 16/34 (47%), Positives = 20/34 (58%)

Query: 84  GEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQ 117
           G+KG+ G  G RG  G  G +GE G PGI   +Q
Sbjct: 31  GKKGEAGRPGRRGRPGLKGEQGEPGAPGIRTGIQ 64


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 38/69 (55%), Positives = 42/69 (60%), Gaps = 6/69 (8%)

Query: 50   RGYQGPPGPPGPPGIPGNHGN------NGNNGATGHEGAKGEKGDKGDLGPRGERGQHGP 103
            RG QG PGP GPPG+PG  G       NG NG  G  G  G KG+KGD G  G  G+ GP
Sbjct: 1814 RGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGP 1873

Query: 104  KGEKGYPGI 112
            KGE+G PGI
Sbjct: 1874 KGERGAPGI 1882



 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 43/98 (43%), Positives = 50/98 (51%), Gaps = 23/98 (23%)

Query: 34   GLPPDCSKCCHGDYSFRGYQGPPGP------PGPPGIPGNHGNNGNNGATGHEGAKGEKG 87
            GLP    K   GD   RG +GPPGP      PG PG+PG  G+ G  G  G  G KGEKG
Sbjct: 1392 GLPGTAMK---GDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448

Query: 88   DK--------------GDLGPRGERGQHGPKGEKGYPG 111
            D               G+ GPRG  G  GPKG++G+PG
Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPG 1486



 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 36/80 (45%), Positives = 47/80 (58%), Gaps = 11/80 (13%)

Query: 51   GYQGPPGPPGP--------PGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGP---RGERG 99
            G  GPPGPPGP        PG+ G  G  G  GA G  G+ G++G KGD G    +G+RG
Sbjct: 2082 GTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRG 2141

Query: 100  QHGPKGEKGYPGIPPELQIA 119
            + GP+G+ G PG+P E  +A
Sbjct: 2142 EPGPRGQDGNPGLPGERGMA 2161



 Score = 71.2 bits (173), Expect = 8e-13
 Identities = 43/127 (33%), Positives = 53/127 (41%), Gaps = 27/127 (21%)

Query: 17   LPFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGA 76
            L   LCQ  +   P+    P  C K   G+    G +G  GPPG PG+PG  G  G  G 
Sbjct: 1229 LATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGP 1288

Query: 77   TGHEGAKGE---------------------------KGDKGDLGPRGERGQHGPKGEKGY 109
             G   AKGE                           KG  G  GPRG+ G+ GP+G KG 
Sbjct: 1289 PGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGE 1348

Query: 110  PGIPPEL 116
            PG P ++
Sbjct: 1349 PGAPGQV 1355



 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 32/69 (46%), Positives = 40/69 (57%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            G+   +G +GPPG PG PG  G  G  G  G  G  G KG++GD G+ G  G  G  GPK
Sbjct: 1634 GEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPK 1693

Query: 105  GEKGYPGIP 113
            G++G PG P
Sbjct: 1694 GDRGEPGPP 1702



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 37/82 (45%), Positives = 43/82 (52%), Gaps = 13/82 (15%)

Query: 45   GDYSFRGYQGPPG-------PPGP------PGIPGNHGNNGNNGATGHEGAKGEKGDKGD 91
            GD    G QGPPG       PPGP      PG PG  G  G  G  G  G  GE+G++G+
Sbjct: 2006 GDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGE 2065

Query: 92   LGPRGERGQHGPKGEKGYPGIP 113
             G RGE+G+ GP G  G PG P
Sbjct: 2066 KGERGEQGRDGPPGLPGTPGPP 2087



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 32/64 (50%), Positives = 40/64 (62%)

Query: 50   RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
            RG +G  G  GP G+ G+ G  G+NG  G +G+KGE GDKG  G  G RG  GP+G+ G 
Sbjct: 2532 RGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGA 2591

Query: 110  PGIP 113
             GIP
Sbjct: 2592 AGIP 2595



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 32/64 (50%), Positives = 39/64 (60%), Gaps = 3/64 (4%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDL---GPRGERGQHGPKGEK 107
            G  G PGPPGPPG+ G+ G  G  GA G  G  G+ G +G++   GP GERG  GP G +
Sbjct: 2374 GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGRE 2433

Query: 108  GYPG 111
            G PG
Sbjct: 2434 GIPG 2437



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 32/69 (46%), Positives = 36/69 (52%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            G     G  GPPG  GPPG  G+ G  G  G  G  G  GE G+KGD GP G+ G  G  
Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKA 1654

Query: 105  GEKGYPGIP 113
            GE+G  G P
Sbjct: 1655 GERGLRGAP 1663



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 34/72 (47%), Positives = 38/72 (52%), Gaps = 6/72 (8%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQ------HGPK 104
            G +G  GPPG PG+PG  G  G  GA G  G  GEKGD+GD G  G  G        G +
Sbjct: 1637 GEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDR 1696

Query: 105  GEKGYPGIPPEL 116
            GE G PG P  L
Sbjct: 1697 GEPGPPGPPGRL 1708



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 34/75 (45%), Positives = 38/75 (50%), Gaps = 12/75 (16%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAK------------GEKGDKGDLGPRGER 98
            G  G PG PG  G+PG  G  G+ G  G  G K            GEKGDKG+ GP G  
Sbjct: 2593 GIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRP 2652

Query: 99   GQHGPKGEKGYPGIP 113
            G  G KGE G PG+P
Sbjct: 2653 GLAGHKGEMGEPGVP 2667



 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 33/83 (39%), Positives = 43/83 (51%), Gaps = 19/83 (22%)

Query: 50   RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGP--------------- 94
            RG +G PG  GP G  G+ G+ G +G  G  G+ G KGD+G+ GP               
Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR 1716

Query: 95   ----RGERGQHGPKGEKGYPGIP 113
                 G+RGQ GP+G KG PG+P
Sbjct: 1717 EKGEPGDRGQEGPRGPKGDPGLP 1739



 Score = 64.7 bits (156), Expect = 7e-11
 Identities = 29/59 (49%), Positives = 35/59 (59%)

Query: 54   GPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGI 112
            G PG PG PG PG  G  G  GA G +G +G  G  G+ G +GERG  GP G +G PG+
Sbjct: 1453 GAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGV 1511



 Score = 64.7 bits (156), Expect = 7e-11
 Identities = 33/70 (47%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 51   GYQGPPGPPGP---------PGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQH 101
            G  G PGPPGP         PG+PG  G  G  GA G +GA G+ GD+G  G  G  G  
Sbjct: 2224 GAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLP 2283

Query: 102  GPKGEKGYPG 111
            GP G KG PG
Sbjct: 2284 GPVGPKGEPG 2293



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 28/69 (40%), Positives = 36/69 (52%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            G+    G++GPPGP G PG+ G  G  G+ G  G +G  G  G  G  GP G  G  G  
Sbjct: 1743 GERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKA 1802

Query: 105  GEKGYPGIP 113
            G+ G  G+P
Sbjct: 1803 GDPGRDGLP 1811



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 31/71 (43%), Positives = 40/71 (56%), Gaps = 2/71 (2%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            G     G  G PG PG  G  G  G++G +G  G +G KGE+G  G LGP+G  G  GP 
Sbjct: 1836 GKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPV 1895

Query: 105  GE--KGYPGIP 113
            G   +G+PG+P
Sbjct: 1896 GPPGQGFPGVP 1906



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 34/82 (41%), Positives = 40/82 (48%)

Query: 30   PQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDK 89
            P T G P         D    G  G  GPPG  G  G  G+NG+ G  G  G  G KGD+
Sbjct: 2081 PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDR 2140

Query: 90   GDLGPRGERGQHGPKGEKGYPG 111
            G+ GPRG+ G  G  GE+G  G
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAG 2162



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 38/66 (57%), Gaps = 2/66 (3%)

Query: 50   RGYQGPPGP--PGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEK 107
            +G++G PG   PG PG PG  G  G+ G  G  GA G  G  G  GPRGE GQ GP GE+
Sbjct: 2365 KGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGER 2424

Query: 108  GYPGIP 113
            G  G P
Sbjct: 2425 GLAGPP 2430



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 14/85 (16%)

Query: 45   GDYSFRGYQGPPGP------PGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGD------- 91
            G+   +G +GPPGP      PG  G PG  G  G  G TG +G KGE G  GD       
Sbjct: 1489 GEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPA 1548

Query: 92   -LGPRGERGQHGPKGEKGYPGIPPE 115
              GP+GE+G  GP G +G  G+  E
Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGE 1573



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 36/87 (41%), Positives = 44/87 (50%), Gaps = 2/87 (2%)

Query: 28   ESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNG--ATGHEGAKGE 85
            E  + G   P  S+   G     G +GP GPPGP G  G  G  G  G  A       G 
Sbjct: 1493 EKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGP 1552

Query: 86   KGDKGDLGPRGERGQHGPKGEKGYPGI 112
            KG+KGD+GP G RG  G +GE+G PG+
Sbjct: 1553 KGEKGDVGPAGPRGATGVQGERGPPGL 1579



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 32/81 (39%), Positives = 42/81 (51%), Gaps = 16/81 (19%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKG----------------DKGDLGP 94
            G +GP G  G  G PG  G NG+ G++G +G +GE G                +KG+ G 
Sbjct: 1664 GVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGD 1723

Query: 95   RGERGQHGPKGEKGYPGIPPE 115
            RG+ G  GPKG+ G PG P E
Sbjct: 1724 RGQEGPRGPKGDPGLPGAPGE 1744



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 33/72 (45%), Positives = 39/72 (54%), Gaps = 4/72 (5%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGD----LGPRGERGQ 100
            G+   RG  G PG  GP G+ G  G+ G  G  G  G+ G KGDKGD    LGP G RG 
Sbjct: 2475 GEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGA 2534

Query: 101  HGPKGEKGYPGI 112
             G  GE+G  G+
Sbjct: 2535 KGDMGERGPRGL 2546



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 32/69 (46%), Positives = 40/69 (57%), Gaps = 6/69 (8%)

Query: 50   RGYQGPPGPPGPPGIPGNHGN------NGNNGATGHEGAKGEKGDKGDLGPRGERGQHGP 103
            +G +G  GPPG PG+ G+ G        G +GA G EG  G KGD+G  G  G +G  G 
Sbjct: 2640 KGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGE 2699

Query: 104  KGEKGYPGI 112
            KGE+G PGI
Sbjct: 2700 KGERGTPGI 2708



 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 30/67 (44%), Positives = 36/67 (53%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            GD  F G  GP G  G  G  G  G  G  G +G++G+ G  G  G +GPRG  G  G K
Sbjct: 2683 GDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQK 2742

Query: 105  GEKGYPG 111
            GE+G PG
Sbjct: 2743 GERGPPG 2749



 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 29/69 (42%), Positives = 37/69 (53%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            G+   RG +GP GP G PG+PG  G  G  G  G  G +G+ G +G  G +G+RG  G  
Sbjct: 1719 GEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLD 1778

Query: 105  GEKGYPGIP 113
            G  G  G P
Sbjct: 1779 GRSGLDGKP 1787



 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 31/67 (46%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 50   RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
            RG  G  GP GPPG+PG  G  G  G  G  G  G KGD+G+ G +GE+G  G +G +G 
Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQ-GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGE 1935

Query: 110  PGIPPEL 116
            PG  P +
Sbjct: 1936 PGSVPNV 1942



 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 34/65 (52%), Positives = 38/65 (58%), Gaps = 4/65 (6%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
            G +G  GPPG  GIPG  G  G  G+ G  GA G KGDKGD G     G  GP+GE+G P
Sbjct: 2422 GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV----GLPGPRGERGEP 2477

Query: 111  GIPPE 115
            GI  E
Sbjct: 2478 GIRGE 2482



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 32/77 (41%), Positives = 38/77 (49%), Gaps = 14/77 (18%)

Query: 51   GYQGPPGPPGP--------------PGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRG 96
            G QGP GPPG               PG PG+ G  G  G  G  G KG++G  G LG  G
Sbjct: 1433 GPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAG 1492

Query: 97   ERGQHGPKGEKGYPGIP 113
            E+G+ GP G  G  G+P
Sbjct: 1493 EKGERGPPGPAGSRGLP 1509



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 28/63 (44%), Positives = 37/63 (58%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
            G +G PG  GP G+ G  G  G++G  G +G  G  G  G +GPRG  G+ G KG++G P
Sbjct: 1586 GPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP 1645

Query: 111  GIP 113
            G P
Sbjct: 1646 GDP 1648



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 31/75 (41%), Positives = 42/75 (56%), Gaps = 11/75 (14%)

Query: 50   RGYQGPPGPPGP---------PGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQ 100
            RG+ G PGP G          PGI G  G +GN+G+ G  G  G  G +G  G +G++G+
Sbjct: 2685 RGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGE 2744

Query: 101  HGPKGEK--GYPGIP 113
             GP GE+  G PG+P
Sbjct: 2745 RGPPGERVVGAPGVP 2759



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 30/72 (41%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 45   GDYSFRGYQGPPGPP----GPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQ 100
            GD    G +G  G      GPPG  G  G+ G  G  G +G KG +GD GD G +G +G+
Sbjct: 2508 GDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGE 2567

Query: 101  HGPKGEKGYPGI 112
             G KG  G PG+
Sbjct: 2568 PGDKGSAGLPGL 2579



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 20/82 (24%)

Query: 51   GYQGPPGPPGPPG--------------------IPGNHGNNGNNGATGHEGAKGEKGDKG 90
            G  GP GPPGPPG                    +PG  G  G  G  G +G  G++G +G
Sbjct: 2434 GIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRG 2493

Query: 91   DLGPRGERGQHGPKGEKGYPGI 112
              GP G RG+ G KG+ G  G+
Sbjct: 2494 LTGPPGSRGERGEKGDVGSAGL 2515



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 30/70 (42%), Positives = 36/70 (51%)

Query: 44   HGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGP 103
            +GD   +G +G PG  G  G PG  G +GN G  G  G  G +G  G  GPRG  G  G 
Sbjct: 2122 NGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGG 2181

Query: 104  KGEKGYPGIP 113
             G+ G PG P
Sbjct: 2182 HGDPGPPGAP 2191



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 33/66 (50%), Positives = 36/66 (54%), Gaps = 4/66 (6%)

Query: 51   GYQGPPGPPGP---PGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEK 107
            G QGP GPPGP    G PG  G  G  G  G +G  G KG+ G+ GP G RG  GP G  
Sbjct: 2168 GLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAV 2226

Query: 108  GYPGIP 113
            G PG P
Sbjct: 2227 GLPGPP 2232



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 36/89 (40%), Positives = 39/89 (43%), Gaps = 18/89 (20%)

Query: 45   GDYSFRGYQGPPGPP------------GPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDL 92
            G   FRG  GP G P            GPPG+ G  G +G  GA G  G  G  G  GD 
Sbjct: 1746 GIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDP 1805

Query: 93   GP------RGERGQHGPKGEKGYPGIPPE 115
            G       RGE+G  GP G  G PG P E
Sbjct: 1806 GRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834



 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 31/72 (43%), Positives = 34/72 (47%), Gaps = 9/72 (12%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGA---------KGEKGDKGDLGPRGERGQH 101
            G +G PG PGP G PG  G  G  G  G  G           G KGD G  GP G RG  
Sbjct: 1323 GLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPL 1382

Query: 102  GPKGEKGYPGIP 113
            G  G +G PG+P
Sbjct: 1383 GDPGPRGPPGLP 1394



 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 38/95 (40%), Positives = 43/95 (45%), Gaps = 26/95 (27%)

Query: 45   GDYSFRGYQGPPGPPGPPGI------PGNHGNNGNNGATGHEGAKGEKGD---------- 88
            GD   RG +GP G PG PG       PG  G  G+ G +G  G +G  GD          
Sbjct: 1335 GDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLP 1394

Query: 89   ----KGDLGPRGERGQHGP------KGEKGYPGIP 113
                KGD G RGERG  GP       GE G PG+P
Sbjct: 1395 GTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLP 1429



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 29/67 (43%), Positives = 33/67 (49%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            GD    G +GP G PG PG PG  G  G  G  G +G  G +G  G+ G RG  G  G  
Sbjct: 1722 GDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRS 1781

Query: 105  GEKGYPG 111
            G  G PG
Sbjct: 1782 GLDGKPG 1788



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 37/91 (40%), Positives = 45/91 (49%), Gaps = 9/91 (9%)

Query: 28   ESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKG 87
            E    GGL  D      G+   +G +G PGP G  G  G  G  G+ G  G +GA G KG
Sbjct: 2311 EKGAPGGLAGDLV----GEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKG 2366

Query: 88   DKGD--LGPRGERGQHGP---KGEKGYPGIP 113
             KGD  +G  G  G  GP   KG+ G PG+P
Sbjct: 2367 FKGDPGVGVPGSPGPPGPPGVKGDLGLPGLP 2397



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 37/87 (42%), Positives = 40/87 (45%), Gaps = 26/87 (29%)

Query: 51   GYQGPP---------------------GPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDK 89
            G  G P                     GPPG  GIPG  G  G  G+ G  GA G KGDK
Sbjct: 2401 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2460

Query: 90   GD-----LGPRGERGQHGPKGEKGYPG 111
            GD      GPRGERG+ G +GE G PG
Sbjct: 2461 GDPGVGLPGPRGERGEPGIRGEDGRPG 2487



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 37/86 (43%), Positives = 41/86 (47%), Gaps = 25/86 (29%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEG--------AKGEKGD-------------- 88
            G +G PG PG PG+PG  G  G  G TG  G        AKGEKG               
Sbjct: 2269 GDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGA 2328

Query: 89   KGDL---GPRGERGQHGPKGEKGYPG 111
            KGD    GPRGE+G+ G  GE G PG
Sbjct: 2329 KGDRGLPGPRGEKGEAGRAGEPGDPG 2354



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 29/64 (45%), Positives = 33/64 (51%)

Query: 50   RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
            +G +G PGP G  G  G  G  G  G+ G  G  G  G KG  GP G  G+ G KGE G 
Sbjct: 1479 KGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGR 1538

Query: 110  PGIP 113
            PG P
Sbjct: 1539 PGDP 1542



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 29/67 (43%), Positives = 32/67 (47%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            GD    G +G  G PGP G  GN G  G  G  G EG  G +G +G  GP G  G  GP 
Sbjct: 2129 GDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPP 2188

Query: 105  GEKGYPG 111
            G  G  G
Sbjct: 2189 GAPGLAG 2195



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 30/67 (44%), Positives = 35/67 (52%), Gaps = 6/67 (8%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGER------GQHGPK 104
            G  G PG  GP G PG  G  G+ G  G  G  GEKG++G  GP G R      G+ G K
Sbjct: 1459 GQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAK 1518

Query: 105  GEKGYPG 111
            G +G PG
Sbjct: 1519 GPEGPPG 1525



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 28/62 (45%), Positives = 33/62 (53%), Gaps = 1/62 (1%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKG-EKGDKGDLGPRGERGQHGPKGEKGY 109
            G QGPPG  GP G PG  G  G+ G  G +G  G   G++G  GP G  G+ G  G  G 
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044

Query: 110  PG 111
            PG
Sbjct: 2045 PG 2046



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 14/86 (16%)

Query: 45   GDYSFRGYQGPPGP------PGPPGIPGNHGNNGNNGATGHEGAKGEKGD--KGDLGPRG 96
            G    +G +GPPGP      PGPPG PG  G  G  G +G +G  GE G   +G  GP G
Sbjct: 2165 GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG 2224

Query: 97   ERGQHGPKGEKGY------PGIPPEL 116
              G  GP G  G       PG+P ++
Sbjct: 2225 AVGLPGPPGPSGLVGPQGSPGLPGQV 2250



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 15/83 (18%)

Query: 44   HGDYSFRGYQGPPGPPGPPGIPGNH---------------GNNGNNGATGHEGAKGEKGD 88
            +GD   +G +G PG  G  G+PG                 G+ G+ G  G  G +GEKGD
Sbjct: 2556 NGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGD 2615

Query: 89   KGDLGPRGERGQHGPKGEKGYPG 111
             G +GPRG +G+ G KG  G  G
Sbjct: 2616 VGFMGPRGLKGERGVKGACGLDG 2638



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 30/71 (42%), Positives = 38/71 (53%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            GD    G  G  G  GP G PG  G  G+ G+ G +G  G +G+KGD+G  G RG  G +
Sbjct: 2569 GDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGER 2628

Query: 105  GEKGYPGIPPE 115
            G KG  G+  E
Sbjct: 2629 GVKGACGLDGE 2639



 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 29/69 (42%), Positives = 35/69 (50%), Gaps = 7/69 (10%)

Query: 50   RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQH-------G 102
            RG +G PG  G  G PG  G  G  G  G  G +GEKGD G  G +G++G         G
Sbjct: 2471 RGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG 2530

Query: 103  PKGEKGYPG 111
            P+G KG  G
Sbjct: 2531 PRGAKGDMG 2539



 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 32/78 (41%), Positives = 41/78 (52%), Gaps = 11/78 (14%)

Query: 45   GDYSFRGYQGPPGP---PGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGER--- 98
            GD   +G +G PG    PGP G  G+ G  G  G+ G  G +G +G KG+ GP GER   
Sbjct: 2695 GDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVG 2754

Query: 99   -----GQHGPKGEKGYPG 111
                 G  G +GE+G PG
Sbjct: 2755 APGVPGAPGERGEQGRPG 2772



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 28/62 (45%), Positives = 33/62 (53%)

Query: 50   RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
            RG +G PG PG PG  G  G  G  G  G  G +G  G+KGD GP G  G+ G  G+ G 
Sbjct: 1730 RGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGA 1789

Query: 110  PG 111
             G
Sbjct: 1790 AG 1791



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 28/67 (41%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 50   RGYQGPPGPPGPPGIPGNH---GNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGE 106
            +G  G PG PG  G PG     G  G+ G  G  G KG++G+KG+ G  G  G  GP G 
Sbjct: 2658 KGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGN 2717

Query: 107  KGYPGIP 113
             G  G P
Sbjct: 2718 DGSAGPP 2724



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 29/66 (43%), Positives = 33/66 (50%), Gaps = 5/66 (7%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEK-----GDKGDLGPRGERGQHGPKG 105
            G  G  GPPGPPG  G  G  G  G  G  G  GE+     G  G  G RGE+G+ GP G
Sbjct: 2716 GNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAG 2775

Query: 106  EKGYPG 111
             +G  G
Sbjct: 2776 PRGEKG 2781



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 29/63 (46%), Positives = 31/63 (49%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYP 110
            G  G  GP GPPG  G  G+ G  G  G  G KGE+G  G  G RG  G  G  G KG  
Sbjct: 1462 GSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPE 1521

Query: 111  GIP 113
            G P
Sbjct: 1522 GPP 1524



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 29/68 (42%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 51   GYQGPPGPPGPPGIPGNHGNNGN-----NGATGHEGAKGEKGDKGDLGPRGERGQHGPKG 105
            G  GP GP GP G+ G  G  G       G TG  G  G  G  G +GP+G  G  G  G
Sbjct: 2192 GLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVG 2251

Query: 106  EKGYPGIP 113
            E G PG P
Sbjct: 2252 ETGKPGAP 2259



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 27/64 (42%), Positives = 33/64 (51%)

Query: 50   RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
            RG +G  G  G  G  G  G  G  G  GH+G  GE G  G  G  G+ G  GPKG++G+
Sbjct: 2628 RGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGF 2687

Query: 110  PGIP 113
             G P
Sbjct: 2688 DGQP 2691



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 14/81 (17%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQ---- 100
            GD  F G  G  G  G  G PG  G+ G  G  G  GAKG +G  G  G +GE+G+    
Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRP 1539

Query: 101  ----------HGPKGEKGYPG 111
                       GPKGEKG  G
Sbjct: 1540 GDPAVVGPAVAGPKGEKGDVG 1560



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 30/64 (46%), Positives = 33/64 (51%), Gaps = 10/64 (15%)

Query: 60   GPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPR-------GERGQHGPK---GEKGY 109
            GP G  G  G  G  G  G  G +G KGD+GD GP+       GERG  GP    GE G 
Sbjct: 1979 GPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGK 2038

Query: 110  PGIP 113
            PGIP
Sbjct: 2039 PGIP 2042



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 32/78 (41%), Positives = 36/78 (46%), Gaps = 17/78 (21%)

Query: 51   GYQGPPGPPGP------PGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQ---- 100
            G QG PG PG       PG PG  G +G +G  G  G  G  G  G +GP+GE G     
Sbjct: 2239 GPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP 2298

Query: 101  -------HGPKGEKGYPG 111
                    G KGEKG PG
Sbjct: 2299 GQAVVGLPGAKGEKGAPG 2316



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 10/79 (12%)

Query: 44   HGDYSFRGYQGPPGPPGPPGIPG----------NHGNNGNNGATGHEGAKGEKGDKGDLG 93
            +G     G +G  G PGPPG PG            G  G+ G  G  G KG+ G  G  G
Sbjct: 1684 NGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPG 1743

Query: 94   PRGERGQHGPKGEKGYPGI 112
             RG  G  GP G +G PG+
Sbjct: 1744 ERGIEGFRGPPGPQGDPGV 1762



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 28/97 (28%)

Query: 45   GDYSFRGYQGPP----------------------------GPPGPPGIPGNHGNNGNNGA 76
            G+    G +GP                             GPPGP G+ G  G  G  G 
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044

Query: 77   TGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIP 113
             G  G  GE G  G+ G RGE+G+ G +G  G PG+P
Sbjct: 2045 PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLP 2081



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 33/85 (38%), Positives = 39/85 (45%), Gaps = 19/85 (22%)

Query: 29   SPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPG------PPGIPGNHGNNGNNG-----AT 77
            +P  GG P        G     G  GPPGPPG      P G+ G  G  G  G     A 
Sbjct: 2705 TPGIGGFP--------GPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAP 2756

Query: 78   GHEGAKGEKGDKGDLGPRGERGQHG 102
            G  GA GE+G++G  GP G RG+ G
Sbjct: 2757 GVPGAPGERGEQGRPGPAGPRGEKG 2781



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/71 (40%), Positives = 32/71 (45%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            G+   RG  G PG PG  G+ G  G  G  G  G  G  G  GD G  G  G  G  GP+
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 105  GEKGYPGIPPE 115
            G  G  G P E
Sbjct: 2201 GPSGLKGEPGE 2211



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 27/67 (40%), Positives = 31/67 (46%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            G+    G +G  GP G PG+ G  G  G  G  G  G  G  G  G  GP+G  G  G  
Sbjct: 2150 GNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209

Query: 105  GEKGYPG 111
            GE G PG
Sbjct: 2210 GETGPPG 2216



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 6/72 (8%)

Query: 50   RGYQGPPGPPGP---PGIPGNHGNNGNNGATGHEGAKGEK---GDKGDLGPRGERGQHGP 103
            +G +G PGP G    PG+PG  G  G  G  G +G +G     G  GD GP G  G  GP
Sbjct: 2137 KGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGP 2196

Query: 104  KGEKGYPGIPPE 115
             G +G  G+  E
Sbjct: 2197 AGPQGPSGLKGE 2208



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 26/67 (38%), Positives = 36/67 (53%), Gaps = 7/67 (10%)

Query: 50   RGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGY 109
            +G +G PGPPGPPG   + G          +G  G++G +G  GP+G+ G  G  GE+G 
Sbjct: 1693 KGDRGEPGPPGPPGRLVDTGPGARE-----KGEPGDRGQEGPRGPKGDPGLPGAPGERGI 1747

Query: 110  PGI--PP 114
             G   PP
Sbjct: 1748 EGFRGPP 1754



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 27/71 (38%), Positives = 34/71 (47%)

Query: 45   GDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK 104
            G     G +GP G  G PG  G+ G  G+ G+ G  G +G  G +G  G  G  G  G  
Sbjct: 2542 GPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSP 2601

Query: 105  GEKGYPGIPPE 115
            G+ G PGI  E
Sbjct: 2602 GKDGVPGIRGE 2612



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 33/118 (27%), Positives = 44/118 (37%), Gaps = 53/118 (44%)

Query: 51   GYQGPPGPPGP--------PGIPGNHGNNGNNGATGHEGAKGEKGDKG------------ 90
            G QGPPG PGP        PG+PG  G  G+ G TG +G +G  G++G            
Sbjct: 1884 GPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVD 1943

Query: 91   ---------------------------------DLGPRGERGQHGPKGEKGYPGIPPE 115
                                               GP+G+ G+ GP G++G  G P E
Sbjct: 1944 RLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGE 2001



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 30/73 (41%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 45   GDYSFRGYQGPPGPPGP------PGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGER 98
            G+    G  G  G  GP      PGI G  G  G  G  G  G +G  G  G  GP+G+R
Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG-QGFPGVPGGTGPKGDR 1915

Query: 99   GQHGPKGEKGYPG 111
            G+ G KGE+G PG
Sbjct: 1916 GETGSKGEQGLPG 1928



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 19/41 (46%), Positives = 24/41 (58%), Gaps = 2/41 (4%)

Query: 50   RGYQGPPGPP--GPPGIPGNHGNNGNNGATGHEGAKGEKGD 88
            +G +GPPG    G PG+PG  G  G  G  G  G +GEKG+
Sbjct: 2742 KGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGE 2782



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 4/57 (7%)

Query: 59   PGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPK----GEKGYPG 111
            P P    G  G++G  G  G EG  G  G++G  G RG+ G  GP     GE+G PG
Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPG 2028



 Score = 35.4 bits (80), Expect = 0.046
 Identities = 30/117 (25%), Positives = 35/117 (29%), Gaps = 39/117 (33%)

Query: 34   GLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGA----------- 82
            GLP        G     G  GP G  G  G  G  G  G  G  G  G+           
Sbjct: 1890 GLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETA 1949

Query: 83   ----------------------------KGEKGDKGDLGPRGERGQHGPKGEKGYPG 111
                                        +G KGD G+ GP G+ G  G  GE+G  G
Sbjct: 1950 GIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG 2006


>gi|38372917 C1q and tumor necrosis factor related protein 1 isoform
           1 [Homo sapiens]
          Length = 281

 Score = 79.0 bits (193), Expect = 4e-15
 Identities = 58/226 (25%), Positives = 102/226 (45%), Gaps = 12/226 (5%)

Query: 23  QDEYMESPQTGGLPPD-CSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEG 81
           Q E     Q  GLP   C +CC    S       P       + G  G+ G+ G  G  G
Sbjct: 56  QHEKYRPSQDQGLPASRCLRCCDPGTSMYPATAVP-QINITILKGEKGDRGDRGLQGKYG 114

Query: 82  AKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFSNQNSGIIFSSVE 141
             G  G +G  GP+G++G  G  GE+           +       H ++    +IF +  
Sbjct: 115 KTGSAGARGHTGPKGQKGSMGAPGERCKSHY---AAFSVGRKKPMHSNHYYQTVIFDTEF 171

Query: 142 TNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKS 201
            N+ + F++ TG+F   V G+YFF+ ++      +E Y+++M N   V  +++ ++  +S
Sbjct: 172 VNLYDHFNMFTGKFYCYVPGLYFFSLNVHTWNQ-KETYLHIMKNEEEVVILFA-QVGDRS 229

Query: 202 DTSSNHAVLKLAKGDEVWLRM-----GNGALHGDHQRFSTFAGFLL 242
              S   +L+L + D+VW+R+      N     +   + TF+G+L+
Sbjct: 230 IMQSQSLMLELREQDQVWVRLYKGERENAIFSEELDTYITFSGYLV 275


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.140    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,655,487
Number of Sequences: 37866
Number of extensions: 755345
Number of successful extensions: 26805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 3921
Number of HSP's gapped (non-prelim): 8098
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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