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Search of human proteins with 13569879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 1 [Homo sapiens]
(268 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 535 e-152
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 440 e-124
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 414 e-116
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 298 4e-81
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 296 1e-80
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens] 235 3e-62
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 230 9e-61
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 230 9e-61
gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens] 170 1e-42
gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens] 163 2e-40
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 86 3e-17
gi|21735415 centromere protein B [Homo sapiens] 76 4e-14
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 76 4e-14
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 74 1e-13
gi|55956788 nucleolin [Homo sapiens] 74 1e-13
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 72 4e-13
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens] 69 3e-12
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 68 7e-12
gi|4504487 histidine rich calcium binding protein precursor [Hom... 67 1e-11
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 67 2e-11
gi|115529449 upstream binding transcription factor, RNA polymera... 67 2e-11
gi|115529451 upstream binding transcription factor, RNA polymera... 67 2e-11
gi|7657671 upstream binding transcription factor, RNA polymerase... 67 2e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 66 3e-11
gi|210032580 SET domain containing 1B [Homo sapiens] 66 3e-11
gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 66 3e-11
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 65 5e-11
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 65 6e-11
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 65 6e-11
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 65 6e-11
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 535 bits (1378), Expect = e-152
Identities = 268/268 (100%), Positives = 268/268 (100%)
Query: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
Sbjct: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
Query: 61 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
Sbjct: 61 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
Sbjct: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
Sbjct: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
EEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 241 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 440 bits (1132), Expect = e-124
Identities = 220/220 (100%), Positives = 220/220 (100%)
Query: 49 MANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEA 108
MANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEA
Sbjct: 1 MANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEA 60
Query: 109 LQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE 168
LQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE
Sbjct: 61 LQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDE 120
Query: 169 DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD 228
DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD
Sbjct: 121 DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD 180
Query: 229 EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 181 EEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 414 bits (1064), Expect = e-116
Identities = 219/268 (81%), Positives = 222/268 (82%), Gaps = 41/268 (15%)
Query: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVE L
Sbjct: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVE------L 54
Query: 61 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
SL +L L NK++ QNLKNLKSLDL
Sbjct: 55 SSLARLPSL----------------------------NKLRK-------QNLKNLKSLDL 79
Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
Sbjct: 80 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 139
Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
Sbjct: 140 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 199
Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
EEEEEEEGGLRGEKRKRDAEDDGEEEDD
Sbjct: 200 EEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 298 bits (762), Expect = 4e-81
Identities = 158/267 (59%), Positives = 204/267 (76%), Gaps = 18/267 (6%)
Query: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
MEM ++I+LELRNR+P +V ELVLDN G++EGL D F+ELEFLS NV L+S+A L
Sbjct: 1 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60
Query: 61 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
P LNKL+KLELSDN +SGGLEVLAEKCPNLT+LNLSGNKIKDLST+E L+ L+NLKSLDL
Sbjct: 61 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120
Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
FNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E +G DDEEE+E+E
Sbjct: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY 179
Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
E + E+EE+E++E+E E+ED +G E E+E G + E+ DEED++ E GE
Sbjct: 180 DEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEEDEE---ELGE 230
Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267
EE RG+KRKR+ ED+GE++D
Sbjct: 231 EE--------RGQKRKREPEDEGEDDD 249
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 296 bits (759), Expect = 1e-80
Identities = 155/266 (58%), Positives = 202/266 (75%), Gaps = 15/266 (5%)
Query: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
M+MK++I+LELRNR+P V ELVLDNC +G+IEGL F LEFLS+ NV L S++ L
Sbjct: 1 MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNL 60
Query: 61 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
P L KL+KLELS+N I GGL++LAEK PNLT+LNLSGNK+KD+ST+E L+ L+ LKSLDL
Sbjct: 61 PKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDL 120
Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
FNCE+TNL DYRES+F+LL Q+TYLDG+D+ED EAPDS+ E D +E+++EE E+E
Sbjct: 121 FNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDE 180
Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
+ EEEE +EE+DEDED + DE E+ E EEE GL DEED+D+ +
Sbjct: 181 DDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGL---------DEEDEDE-----D 226
Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEE 266
E+EEEEEGG +GEKRKR+ +D+GE++
Sbjct: 227 EDEEEEEGG-KGEKRKRETDDEGEDD 251
>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
Length = 234
Score = 235 bits (600), Expect = 3e-62
Identities = 139/256 (54%), Positives = 175/256 (68%), Gaps = 22/256 (8%)
Query: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
MEM ++I+ ELRNR+P +V EL LDN G++E L D F+ELEFLS N L+S++ L
Sbjct: 1 MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60
Query: 61 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
P L KLRKLEL +SGGLEVLAEKCPNLT+L LSGNKIKDLST+E L+ L+NLKSLDL
Sbjct: 61 PKL-KLRKLELR---VSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116
Query: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
FNCE+TNL DY E++F+LL Q+TYLD + EAP S+ ED +G DDEEE E+E
Sbjct: 117 FNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEG-LDDEEEGEHEEEY 175
Query: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240
E + E+EE EE+E+E E+ED +G G+EE DEE +D +GE
Sbjct: 176 DEDAQVVEDEEGEEEEEEGEEEDVSG-----GDEE------------DEEGYNDGEVDGE 218
Query: 241 EEEEEEEGGLRGEKRK 256
E+EEE RG+KRK
Sbjct: 219 EDEEELGEEERGQKRK 234
Score = 33.5 bits (75), Expect = 0.20
Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 225 EIQDEEDDDDYVEEGEEEEE-EEEGGLRGEKRKRDAEDDGEEED 267
+I+D + D EEGE EEE +E+ + ++ + E++GEEED
Sbjct: 155 DIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEED 198
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 230 bits (587), Expect = 9e-61
Identities = 130/254 (51%), Positives = 171/254 (67%), Gaps = 25/254 (9%)
Query: 15 SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDN 74
S V E VLDNC + +IE L F LEFL + NV L S++ LP L KL+K LS+N
Sbjct: 35 SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94
Query: 75 IISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRES 134
I GGL + AEK PNLT+LNLSG K+KD+ST+E L+ L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95 RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154
Query: 135 IFELLQQITYLDGFDQEDNEAPDSE------EEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
+F+LL Q+T LD +D ED EAPDS+ ++++ED + +DE++ ENE G EEE
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDG------EEE 208
Query: 189 EEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG 248
E +EEEDEDED + D+ E+ E EEE GL +DE+D+D E E+EEEEE G
Sbjct: 209 ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLD-------KDEDDED----EDEDEEEEESG 257
Query: 249 GLRGEKRKRDAEDD 262
+GE RKR+ +D+
Sbjct: 258 --KGENRKRETDDE 269
>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 230 bits (587), Expect = 9e-61
Identities = 130/254 (51%), Positives = 171/254 (67%), Gaps = 25/254 (9%)
Query: 15 SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDN 74
S V E VLDNC + +IE L F LEFL + NV L S++ LP L KL+K LS+N
Sbjct: 35 SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94
Query: 75 IISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRES 134
I GGL + AEK PNLT+LNLSG K+KD+ST+E L+ L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95 RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154
Query: 135 IFELLQQITYLDGFDQEDNEAPDSE------EEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
+F+LL Q+T LD +D ED EAPDS+ ++++ED + +DE++ ENE G EEE
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDG------EEE 208
Query: 189 EEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG 248
E +EEEDEDED + D+ E+ E EEE GL +DE+D+D E E+EEEEE G
Sbjct: 209 ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLD-------KDEDDED----EDEDEEEEESG 257
Query: 249 GLRGEKRKRDAEDD 262
+GE RKR+ +D+
Sbjct: 258 --KGENRKRETDDE 269
>gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]
Length = 131
Score = 170 bits (430), Expect = 1e-42
Identities = 86/131 (65%), Positives = 104/131 (79%)
Query: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60
MEM K I+LELRNR+P +V EL LDN G++EGL D F+ELE L+ N+ L+S+A L
Sbjct: 1 MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60
Query: 61 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120
P LNKL+KLELS N S GLEVLAEKCPNL +LNLSGNKIKDLST+E L+ L+NL+SLDL
Sbjct: 61 PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120
Query: 121 FNCEITNLEDY 131
F CE+TNL +Y
Sbjct: 121 FTCEVTNLNNY 131
>gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]
Length = 450
Score = 163 bits (412), Expect = 2e-40
Identities = 93/185 (50%), Positives = 119/185 (64%), Gaps = 6/185 (3%)
Query: 15 SPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDN 74
S V E VLDNC + +IE L F LEFL + NV L S++ LP L KL+K LS+N
Sbjct: 35 SAARVREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSEN 94
Query: 75 IISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRES 134
I GGL + AEK PNLT+LNLSG K+KD+ST+E L+ L+ LKSLDLFNCE+ NL DY+ES
Sbjct: 95 RIFGGLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQES 154
Query: 135 IFELLQQITYLDGFDQEDNEAPDSEEE--DDEDGDEDDEEEE----ENEAGPPEGYEEEE 188
+F+LL Q+T LD +D ED EAPDS+ + D G E + A PPE +
Sbjct: 155 VFKLLPQLTCLDTYDPEDQEAPDSDAQLLADPWGKEYHTNNAPLLLRSPAWPPEPSIRPQ 214
Query: 189 EEEEE 193
E++ E
Sbjct: 215 EQDYE 219
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 86.3 bits (212), Expect = 3e-17
Identities = 51/126 (40%), Positives = 76/126 (60%), Gaps = 6/126 (4%)
Query: 145 LDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
++G + E+ + EEE++ +G+E++ E EE E EG EEE E + EE+ +E E E+E
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG---EGEEEEGEGKGEEEGEEGEGEEE 870
Query: 205 AGSELGEGEEEVGLSYLMKE---EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAED 261
GEGEEE G +E E ++EE + + EEGE E EEEEG +GE+ + E
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930
Query: 262 DGEEED 267
+GEEE+
Sbjct: 931 EGEEEE 936
Score = 85.5 bits (210), Expect = 4e-17
Identities = 57/126 (45%), Positives = 73/126 (57%), Gaps = 9/126 (7%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEE---ENEAGPPEGYEEEEE----EEEEEDEDEDEDED 203
E+ E EE+ E+G+ + EEEE E E G EG EEE E EEE E E E+E E
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972
Query: 204 EAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE-EEEEEEEGGLRGEKRKRDAED 261
E GEGEEE G +EE ++E E++ + EEGE E EEEEEG + GE + E
Sbjct: 973 EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEG 1032
Query: 262 DGEEED 267
+GEEE+
Sbjct: 1033 EGEEEE 1038
Score = 84.7 bits (208), Expect = 8e-17
Identities = 55/125 (44%), Positives = 73/125 (58%), Gaps = 9/125 (7%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED--EAGSE 208
ED E EEE + +G+E++ E E E G EG E E E EEEE E E E+E+ E G E
Sbjct: 942 EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Query: 209 LGEGEEEVGLSYLMKEE--IQDEEDDDDYVEEGEEEEEEEEGGLR-----GEKRKRDAED 261
GEGEEE +EE ++ E + ++ EGEEEE EEEG R GE+ +R+ E+
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE 1061
Query: 262 DGEEE 266
+ EEE
Sbjct: 1062 EEEEE 1066
Score = 84.0 bits (206), Expect = 1e-16
Identities = 53/118 (44%), Positives = 68/118 (57%), Gaps = 5/118 (4%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE-EEEEDEDEDEDEDEAGSEL 209
E+ E EEE + +G+E+ E E E E G EG EE E E EEEE E + E+E E G
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE-- 929
Query: 210 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
GEGEEE G E + EE++ ++ EGEEEE E EG GE + E +GEEE+
Sbjct: 930 GEGEEEEGEGEGEDGEGEGEEEEGEW--EGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985
Score = 81.3 bits (199), Expect = 8e-16
Identities = 51/122 (41%), Positives = 70/122 (57%), Gaps = 11/122 (9%)
Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
+G +E+ E EEE + +G+E+ E E E E G +G EE EE E E +E+E E E E
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943
Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265
G GEGEEE G + E ++EE + + EEGE E EE EG E + + E +GEE
Sbjct: 944 GE--GEGEEEEG-----EWEGEEEEGEGEGEEEGEGEGEEGEG----EGEEEEGEGEGEE 992
Query: 266 ED 267
E+
Sbjct: 993 EE 994
Score = 79.0 bits (193), Expect = 4e-15
Identities = 52/118 (44%), Positives = 68/118 (57%), Gaps = 6/118 (5%)
Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
+E+ + + EEE+ E E+ EE E E G E + E EEEEEE E E+E E E E
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE-EGEGEEEE 846
Query: 210 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
GEGEEE G EE +E + ++ EEGE E EEEEG GE+ + E +GEEE+
Sbjct: 847 GEGEEEEGEG--KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE---EGEGEGEEEE 899
Score = 78.2 bits (191), Expect = 7e-15
Identities = 52/132 (39%), Positives = 73/132 (55%), Gaps = 11/132 (8%)
Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYE-------EEEEEEEEEDEDE 198
+G +E+ + EEE + +G+E++ E E E G EG E EEE EE E + +E
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 199 DEDEDEAGSELGEGEEEVGLSYLMKE--EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 256
+E E E GEGEEE G +E E + EE+ + EEGE E EEEEG GE +
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG--EGEGEE 992
Query: 257 RDAEDDGEEEDD 268
+ E++GEEE +
Sbjct: 993 EEGEEEGEEEGE 1004
Score = 77.8 bits (190), Expect = 9e-15
Identities = 56/120 (46%), Positives = 67/120 (55%), Gaps = 13/120 (10%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEE---EEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
E+ E EEE + G+E+ EE EEE E G EG EEEE E E E+E E E E+E G
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG-EEEEGEGEGEEEGEGEGEEEEGE 901
Query: 208 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
GEGEEE EE + E ++ EEGE E EEEEG GE D E +GEEE+
Sbjct: 902 --GEGEEE---GEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE----DGEGEGEEEE 952
Score = 76.3 bits (186), Expect = 3e-14
Identities = 53/131 (40%), Positives = 71/131 (54%), Gaps = 23/131 (17%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEA--------GPPEGYEEEE---EEEEEEDED 197
+++ E EE+ +E+GD+ + EEEE E G EG E EE E EEEE+E
Sbjct: 774 ERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833
Query: 198 EDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKR 257
E E+E+ GEGEEE G EE + E ++ EEGE EEE EEG GE +
Sbjct: 834 EGEEEE------GEGEEEEGEG----EEEEGEGKGEEEGEEGEGEEEGEEG--EGEGEEE 881
Query: 258 DAEDDGEEEDD 268
+ E +GEEE +
Sbjct: 882 EGEGEGEEEGE 892
Score = 75.5 bits (184), Expect = 5e-14
Identities = 49/129 (37%), Positives = 69/129 (53%), Gaps = 18/129 (13%)
Query: 146 DGFDQEDNEAPDSEEE-DDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
+G ++ + E + E E ++E+G+ + EEEE E G EG EEE E E E+E+E E E E
Sbjct: 965 EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024
Query: 205 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE--------EEEEEEEGGLRGEKRK 256
E GEGE E E + EE+ ++ +EGE EEEEEEEG + +
Sbjct: 1025 VEGEEGEGEGE---------EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEE 1075
Query: 257 RDAEDDGEE 265
+ DGEE
Sbjct: 1076 ENERQDGEE 1084
Score = 72.4 bits (176), Expect = 4e-13
Identities = 57/160 (35%), Positives = 84/160 (52%), Gaps = 17/160 (10%)
Query: 124 EITNLEDYRESIFELLQQITYLDGFDQEDNEAPDS--EEE----DDEDGDEDDEEEEENE 177
E+ E++++ E +Q G +E N+ + EEE ++E+GD ++EEE+E E
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754
Query: 178 AGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE--------LGEGEEEVGLSYLMKEEIQDE 229
G EG EE E E E++E E + E+ AG E GEGEEE ++E E
Sbjct: 755 -GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813
Query: 230 EDDDDYVE-EGEEEEEEEEG-GLRGEKRKRDAEDDGEEED 267
+ + E +GE EEEEEEG G E + E +GEEE+
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE 853
Score = 71.6 bits (174), Expect = 7e-13
Identities = 47/123 (38%), Positives = 66/123 (53%), Gaps = 10/123 (8%)
Query: 149 DQEDNEAPDSE---EEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
DQ + E ++E EE +E G+ + E EE + E EE E EEEE + +E+E E E
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851
Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265
G+GEEE EE + EE+ ++ EGEEEE E EG GE + E +GE
Sbjct: 852 EEGEGKGEEE-------GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEG 904
Query: 266 EDD 268
E++
Sbjct: 905 EEE 907
Score = 71.2 bits (173), Expect = 9e-13
Identities = 48/121 (39%), Positives = 69/121 (57%), Gaps = 11/121 (9%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEE-ENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
++E+ E EE ++ +G+E+ EE E E E EG EEE E E E+E+ + + +E G
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE 909
Query: 208 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG-GLRGEKRKRDAEDDGEEE 266
GEGEEE G E + EE+ ++ EGEEEE E EG GE + + E +GEEE
Sbjct: 910 --GEGEEEEG-------EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960
Query: 267 D 267
+
Sbjct: 961 E 961
Score = 66.2 bits (160), Expect = 3e-11
Identities = 44/130 (33%), Positives = 70/130 (53%), Gaps = 11/130 (8%)
Query: 149 DQEDNEAPDSEEEDDEDGDE--DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED--- 203
D+E+ E + E +++ +G+E + E+EE E E +EE+ EEE D+ E E+E+
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803
Query: 204 -----EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRD 258
E G E+ GE E G +EE + E ++++ E EE E EEE G G+ +
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG-EGKGEEEG 862
Query: 259 AEDDGEEEDD 268
E +GEEE +
Sbjct: 863 EEGEGEEEGE 872
Score = 64.7 bits (156), Expect = 8e-11
Identities = 47/129 (36%), Positives = 66/129 (51%), Gaps = 12/129 (9%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE---EEEEDEDEDEDEDEAGS 207
E E + EE + E E+ E ++E AG E EEE ++ EEEE E E+++E G
Sbjct: 754 EGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813
Query: 208 -ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL--------RGEKRKRD 258
E GE EE G +EE + EE++ + EE E EEEE G GE+ +
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Query: 259 AEDDGEEED 267
E +GEEE+
Sbjct: 874 GEGEGEEEE 882
Score = 61.2 bits (147), Expect = 9e-10
Identities = 42/126 (33%), Positives = 64/126 (50%), Gaps = 12/126 (9%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAG-- 206
++E E E + G+ + E E+ E +G E+E++E E+ + E E E G
Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE 732
Query: 207 SELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE----EEEEEEEGGLRGEKRKRDAEDD 262
E GEGEEE G + ++EE + + EEGE E E E+E G R ++ + E+
Sbjct: 733 EEHGEGEEEEG------DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786
Query: 263 GEEEDD 268
GEEE D
Sbjct: 787 GEEEGD 792
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/130 (32%), Positives = 70/130 (53%), Gaps = 27/130 (20%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEE--EEEEEEEDEDEDEDEDEAG 206
++E+ + D EE++ ++ ++ ++E E EG EEE E EEEE D +E+E+++ G
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEM--EEGGEEEHGEGEEEEGDREEEEEKEGEG 755
Query: 207 SELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE--------EEGGLRGEKRKRD 258
E GEGEE ++ E + EEGE ++EE EE G +GE + +
Sbjct: 756 KEEGEGEE-----------VEGEREK----EEGERKKEERAGKEEKGEEEGDQGEGEEEE 800
Query: 259 AEDDGEEEDD 268
E GEE+++
Sbjct: 801 TEGRGEEKEE 810
Score = 42.7 bits (99), Expect = 3e-04
Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 17/146 (11%)
Query: 138 LLQQITYLDGFDQEDNEAPDSEE--EDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEED 195
+ Q T ++ F E+ E P+ +E ED + +++E E NE +E+ E D
Sbjct: 569 MTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSD 628
Query: 196 EDEDEDEDEAGSELGEGEEEVG----------LSYLMKEEIQDEEDDDDYVEEGEEE--- 242
+ D+ E G GE E G E QDEE + ++G E
Sbjct: 629 DLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMER 688
Query: 243 --EEEEEGGLRGEKRKRDAEDDGEEE 266
E E+E + E +KRD E+ ++E
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKE 714
Score = 42.0 bits (97), Expect = 6e-04
Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 13/119 (10%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
D ++A SE + G+ +D E + EG E ++EE E ++D+ E
Sbjct: 628 DDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEME 687
Query: 209 L-GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
GEGE+E+ KEE + + ++ +E++E E+G ++R ++ E+ GEEE
Sbjct: 688 RPGEGEKELA----EKEEWKKRDGEE------QEQKEREQG--HQKERNQEMEEGGEEE 734
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 75.9 bits (185), Expect = 4e-14
Identities = 56/148 (37%), Positives = 76/148 (51%), Gaps = 34/148 (22%)
Query: 143 TYLDGFDQEDNEAPDSEEEDDEDGDEDDE--EEEENEAGPPE--GYEEEEEEEEEEDEDE 198
T L +E+ E + EEE++ +G+E++E EEEE E G E G EEE EEE + D DE
Sbjct: 399 TSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDE 458
Query: 199 DEDEDEAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEG 239
+E+EDE S G +G E G S Y +EE Q E+ D D EE
Sbjct: 459 EEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEED 518
Query: 240 EEEEEEEEGGLRGEKRKRDAEDDGEEED 267
+EEE++E D +DD +EED
Sbjct: 519 DEEEDDE-----------DEDDDDDEED 535
Score = 75.1 bits (183), Expect = 6e-14
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 33/144 (22%)
Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE--GYEEEEEEEEEEDEDEDEDED 203
+G ++E+ E + EEE + + +E++ EEEE E G E G EEE EEE + D DE+E+ED
Sbjct: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463
Query: 204 EAGSELG-------EGEEEVGLS---YLMKEEIQ---------DEEDDDDYVEEGEEEEE 244
E S G +G E G S Y +EE Q E+ D D EE +EEE+
Sbjct: 464 EESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEED 523
Query: 245 EEEGGLRGEKRKRDAEDDGEEEDD 268
+E+ EDD ++E+D
Sbjct: 524 DED------------EDDDDDEED 535
Score = 46.2 bits (108), Expect = 3e-05
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 33/103 (32%)
Query: 147 GFDQEDNEAPDSEEEDDEDGDEDDEEEEEN---------------EAGPP---------- 181
G +E E + EEE D D DE++EE+EE+ EAG
Sbjct: 437 GEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEA 496
Query: 182 --------EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
EG E+ + + EEED++E++DEDE + E +EV
Sbjct: 497 QCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
Score = 40.8 bits (94), Expect = 0.001
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 144 YLDGFDQEDN--EAPDSEEEDDEDGDEDDEEEEENEAGPP 181
+L+G + D+ E D EEEDDED D+DD+EE+ +E P
Sbjct: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 75.9 bits (185), Expect = 4e-14
Identities = 65/187 (34%), Positives = 99/187 (52%), Gaps = 32/187 (17%)
Query: 37 LND-TFKELEFLSMANVELSSLARLPSLNKLRKLELSDNII-SGGLEVLAEKC----PNL 90
LND TF E ++MA L +L ++ + D ++ S G +A+ P L
Sbjct: 243 LNDNTFTEKGAVAMAET-------LKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKL 295
Query: 91 TYLNLSGNKIKD---LSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDG 147
LNLS +IK L+ EA+ + L+ LDL N E E LQ++ L+G
Sbjct: 296 KELNLSFCEIKRDAALAVAEAMADKAELEKLDL------NGNTLGEEGCEQLQEV--LEG 347
Query: 148 FDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
F+ A S++ED+E+ +E +EEEEE E EEEEE+EEE+E+E+E+E+E
Sbjct: 348 FNMAKVLASLSDDEDEEEEEEGEEEEEEAE--------EEEEEDEEEEEEEEEEEEEEPQ 399
Query: 208 ELGEGEE 214
+ G+GE+
Sbjct: 400 QRGQGEK 406
Score = 55.5 bits (132), Expect = 5e-08
Identities = 64/212 (30%), Positives = 99/212 (46%), Gaps = 39/212 (18%)
Query: 54 LSSLARLPSLNKL-RKLELSDNIISG-GLEVLAEKCPNLTY---LNLSGNKIKDLSTV-- 106
+++LA+ ++N L R + L+DN + G +AE L +N ++ V
Sbjct: 225 ITALAQAFAVNPLLRVINLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAI 284
Query: 107 -EALQN-LKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDE 164
+A++ L LK L+L CEI D ++ E + L+ D N
Sbjct: 285 ADAIRGGLPKLKELNLSFCEIKR--DAALAVAEAMADKAELEKLDLNGNTL--------- 333
Query: 165 DGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKE 224
G+E E+ +E EG+ + D DEDE+E+E EGEEE +E
Sbjct: 334 -GEEGCEQLQE----VLEGFNMAKVLASLSD-DEDEEEEE------EGEEE-------EE 374
Query: 225 EIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 256
E ++EE++D+ EE EEEEEEEE RG+ K
Sbjct: 375 EAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEK 406
Score = 42.4 bits (98), Expect = 4e-04
Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query: 191 EEEEDEDEDEDEDEAGSELGEGE----EEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 246
E D+ E E D G+ LGE +EV + M + + DD+D EE E EEEEE
Sbjct: 315 EAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEE 374
Query: 247 EGGLRGEKRKRDAEDDGEEEDD 268
E E+ + + E++ EEE++
Sbjct: 375 EAEEEEEEDEEEEEEEEEEEEE 396
Score = 34.7 bits (78), Expect = 0.090
Identities = 22/82 (26%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 187 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 246
++ E E+ D + + +E +L E E ++ ++ DE+++++ E EEEE EE
Sbjct: 319 DKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEE 378
Query: 247 EGGLRGEKRKRDAEDDGEEEDD 268
E E+ + E++ EEE++
Sbjct: 379 E-----EEEDEEEEEEEEEEEE 395
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 74.3 bits (181), Expect = 1e-13
Identities = 43/97 (44%), Positives = 62/97 (63%), Gaps = 12/97 (12%)
Query: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
D EEE++E+ +E++EEEEE E E +EEEEE+EEE E+E+E+E+E E E E E+
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEE----EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942
Query: 217 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
E ++EE+D++ EE EE E+ E G GE
Sbjct: 943 --------EEEEEEEDEEEEEELEEVEDLEFGTAGGE 971
Score = 70.5 bits (171), Expect = 1e-12
Identities = 45/99 (45%), Positives = 59/99 (59%), Gaps = 20/99 (20%)
Query: 156 PDSEEED-------DEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
P + EED D +E++EEEEE E EEEEEEEEE+ E+E+EDE+E E
Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEE-------EEEEEEEEEDFEEEEEDEEEYFEE 923
Query: 209 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
E EEE +EE ++EE + + EE E+EEEEEE
Sbjct: 924 EEEEEEE------FEEEFEEEEGELEEEEEEEDEEEEEE 956
Score = 63.5 bits (153), Expect = 2e-10
Identities = 35/76 (46%), Positives = 50/76 (65%), Gaps = 1/76 (1%)
Query: 187 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY-VEEGEEEEEE 245
+EEEEEEE+E+E+E+E+E E E EEE Y +EE ++EE ++++ EEGE EEEE
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 246 EEGGLRGEKRKRDAED 261
EE E+ + ED
Sbjct: 947 EEEDEEEEEELEEVED 962
Score = 54.7 bits (130), Expect = 8e-08
Identities = 33/84 (39%), Positives = 48/84 (57%), Gaps = 22/84 (26%)
Query: 185 EEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 244
EEEEEEEEEE+E+E+E+E+E E+ ++EE+D+ EE EEEE
Sbjct: 888 EEEEEEEEEEEEEEEEEEEE-------------------EDFEEEEEDE---EEYFEEEE 925
Query: 245 EEEGGLRGEKRKRDAEDDGEEEDD 268
EEE E + + E + EEE++
Sbjct: 926 EEEEEFEEEFEEEEGELEEEEEEE 949
Score = 54.3 bits (129), Expect = 1e-07
Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 10/116 (8%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEEN---EAGPPEGY---EEEEEEEEEEDEDEDEDE 202
++E+ E + EEED+E+ E++EEEEE E EG EEEEE+EEEE+E E+ ++
Sbjct: 903 EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
Query: 203 DEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE----EEEEGGLRGEK 254
E G+ GE EE + + E E E E E EE G E+
Sbjct: 963 LEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEER 1018
Score = 53.1 bits (126), Expect = 2e-07
Identities = 29/68 (42%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEE-DEDEDEDEDE 204
+ F++E+ + + EE++E+ +E +EE EE E E EEE+EEEEEE +E ED +
Sbjct: 908 EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGT 967
Query: 205 AGSELGEG 212
AG E+ EG
Sbjct: 968 AGGEVEEG 975
Score = 37.7 bits (86), Expect = 0.011
Identities = 18/56 (32%), Positives = 35/56 (62%)
Query: 213 EEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
EE++ + + + ++EE++++ EE EEEEEEE+ E + E++ EEE++
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930
Score = 30.8 bits (68), Expect = 1.3
Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 6/63 (9%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
++E + P EE+ EDG + + E A EEE E E E + +++++D+ +
Sbjct: 1055 EEEPSAPPTLLEEETEDGSDKVQPPPETPA------EEEMETETEAEALQEKEQDDTAAM 1108
Query: 209 LGE 211
L +
Sbjct: 1109 LAD 1111
Score = 29.6 bits (65), Expect = 2.9
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 6/83 (7%)
Query: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEE------EDEDEDEDEDEAGSELG 210
+ E E G E EE + PP EEE E+ + E E+E E E +E
Sbjct: 1038 EREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEAL 1097
Query: 211 EGEEEVGLSYLMKEEIQDEEDDD 233
+ +E+ + ++ + I DD+
Sbjct: 1098 QEKEQDDTAAMLADFIDCPPDDE 1120
Score = 28.9 bits (63), Expect = 4.9
Identities = 29/97 (29%), Positives = 39/97 (40%), Gaps = 19/97 (19%)
Query: 154 EAPDSEEEDDEDG------------DEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDED 201
E P +EEE D E + E E AGPP +E EEE E+
Sbjct: 1010 EEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPP--QELVEEEPSAPPTLLEE 1067
Query: 202 EDEAGSELGEGEEEVGLSYLMK-----EEIQDEEDDD 233
E E GS+ + E M+ E +Q++E DD
Sbjct: 1068 ETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 73.9 bits (180), Expect = 1e-13
Identities = 41/135 (30%), Positives = 70/135 (51%), Gaps = 25/135 (18%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
+ D E D EED+ED +++DE+E+E E + E+E+DED+++DED+ E
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202
Query: 209 LGEGEEE---------------VGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
+ EEE V + E +DEE+DD+ ++ ++E++E++
Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD------ 256
Query: 254 KRKRDAEDDGEEEDD 268
D EDD EEE++
Sbjct: 257 ----DDEDDEEEEEE 267
Score = 70.5 bits (171), Expect = 1e-12
Identities = 40/138 (28%), Positives = 77/138 (55%), Gaps = 30/138 (21%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEE----ENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
D+E+++ + +EEDDED DED++E E + A P +E++E++E++++D+D++ED+
Sbjct: 146 DEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDD 205
Query: 205 AGSELGEGEEEVGLSYLM--------------KEEIQDEEDDDDYVEEGEEEEEEEEGGL 250
+ E E G +EE ++EDDDD +E +E++++E+
Sbjct: 206 SEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD--DEDDEDDDDED--- 260
Query: 251 RGEKRKRDAEDDGEEEDD 268
D E++ EEE++
Sbjct: 261 -------DEEEEEEEEEE 271
Score = 68.9 bits (167), Expect = 4e-12
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 30/128 (23%)
Query: 156 PDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-------AGSE 208
P ++ ++ ++D +EEE++ + EE+EE++EDEDEDEDE E A +
Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDD-------DSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP 182
Query: 209 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE--------KRKRDAE 260
E E++ E+ +D+EDDDD E+ EEE E +G+ K K AE
Sbjct: 183 ASEDEDD--------EDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
Query: 261 DDGEEEDD 268
D+ EEEDD
Sbjct: 235 DEDEEEDD 242
Score = 66.6 bits (161), Expect = 2e-11
Identities = 39/129 (30%), Positives = 69/129 (53%), Gaps = 29/129 (22%)
Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE------EEEEEEDEDEDEDED 203
+++++ D ++EDD+D +EDD EEE E P +G + + + E++++E++DED
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244
Query: 204 EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE------GGLRGEKRKR 257
E ++ +D+EDDDD +E EEEEEEEE G + E K+
Sbjct: 245 ED-----------------DDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQ 287
Query: 258 DAEDDGEEE 266
A + +++
Sbjct: 288 KAAPEAKKQ 296
Score = 52.8 bits (125), Expect = 3e-07
Identities = 30/109 (27%), Positives = 54/109 (49%), Gaps = 24/109 (22%)
Query: 146 DGFDQEDNEAPDSEEE------------------------DDEDGDEDDEEEEENEAGPP 181
D D +D+E DSEEE +DED +EDDE+E++++
Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD 253
Query: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 230
E ++E++EEEEE+E+E+ ++ G E ++ K++++ E
Sbjct: 254 EDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302
Score = 31.6 bits (70), Expect = 0.76
Identities = 14/40 (35%), Positives = 26/40 (65%), Gaps = 3/40 (7%)
Query: 170 DEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
++ + + A PP+ E EE+ E+E+ EDE++D +G E+
Sbjct: 10 NQGDPKKMAPPPK---EVEEDSEDEEMSEDEEDDSSGEEV 46
Score = 28.1 bits (61), Expect = 8.4
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 179 GPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGE 211
G P+ +E EE+ EDE+ EDE GE
Sbjct: 12 GDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGE 44
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 72.4 bits (176), Expect = 4e-13
Identities = 47/123 (38%), Positives = 64/123 (52%), Gaps = 23/123 (18%)
Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
DG + D + D EE ED DE +E+EE+E EG EEEEE EEEDED+DED
Sbjct: 94 DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE----EGDREEEEEIEEEDEDDDED---- 145
Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265
GE E+ EE ++EE+++ EE EEE E+ + + +D E D
Sbjct: 146 ----GEDVED--------EEEEEEEEEE---EEEEEENEDHQMNCHNTRIMQDTEKDDNN 190
Query: 266 EDD 268
D+
Sbjct: 191 NDE 193
Score = 64.7 bits (156), Expect = 8e-11
Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 210
EDN+ P E+E+DE+GD ++EEE E E + E+ E+ E+EE+E+E+E+E+E E
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169
Query: 211 EGEEEVGLSYLMKEEIQDEEDDDDY 235
+ + + +M++ +D+ ++D+Y
Sbjct: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194
Score = 51.6 bits (122), Expect = 7e-07
Identities = 36/110 (32%), Positives = 51/110 (46%), Gaps = 35/110 (31%)
Query: 159 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 218
+E DD DG ED +E+EE+E EE ED DE DEDE
Sbjct: 88 DECDDSDGTEDMDEKEEDEG-----------EEYSEDNDEPGDEDE-------------- 122
Query: 219 SYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
E+++ D EE E EEE+E+ GE + + E++ EEE++
Sbjct: 123 ----------EDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE 162
Score = 43.9 bits (102), Expect = 1e-04
Identities = 32/122 (26%), Positives = 59/122 (48%), Gaps = 8/122 (6%)
Query: 129 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG----- 183
E+ E E ++I D D ED E D E+E++E+ +E++EEEEE
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGE--DVEDEEEEEEEEEEEEEEEENEDHQMNCHNTR 179
Query: 184 -YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE 242
++ E+++ DE ++ DE A S L G+ +Y + E + + + +E+ ++
Sbjct: 180 IMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDK 239
Query: 243 EE 244
E
Sbjct: 240 NE 241
Score = 38.9 bits (89), Expect = 0.005
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%)
Query: 168 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 226
+D + +E P + + +E +D D ED DE KEE
Sbjct: 64 QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105
Query: 227 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
+ EE +D E G+E+EE+ E G R E+ + + ED+ ++ED
Sbjct: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145
>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
Length = 1726
Score = 69.3 bits (168), Expect = 3e-12
Identities = 44/132 (33%), Positives = 69/132 (52%), Gaps = 14/132 (10%)
Query: 149 DQEDNEAPDSEEEDDEDGD------------EDDEEEEENEAGPPEGYEEEEEEEEEEDE 196
D ++EA +SEEE +++G+ EDD+EEEE E + + + +D+
Sbjct: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
Query: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD--EEDDDDYVEEGEEEEEEEEGGLRGEK 254
DEDE E++ GS+ G+ E++VG + D E+DD D +EE + + R K
Sbjct: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
Query: 255 RKRDAEDDGEEE 266
+ D EDD EEE
Sbjct: 123 KMSDDEDDDEEE 134
Score = 57.8 bits (138), Expect = 1e-08
Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 14/112 (12%)
Query: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
D E + E+ +E+ +E E + + EEE+++EEE+E+ +D+DE G+
Sbjct: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGN--------- 53
Query: 217 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
+K I D++D+D+ E+ + + E + +KRKR + DD E+DD
Sbjct: 54 -----LKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100
Score = 48.5 bits (114), Expect = 6e-06
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 14/123 (11%)
Query: 148 FDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-- 204
+ +E++E EE +DG+ E+ +E E PPE EE++EE + +D D+D
Sbjct: 135 YGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLK 194
Query: 205 -----------AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
+ L E +E G+ + E + E D++ EE E E++E EG +R
Sbjct: 195 KPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVR 254
Query: 254 KRK 256
+K
Sbjct: 255 PKK 257
Score = 28.9 bits (63), Expect = 4.9
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Query: 188 EEEEEEEDEDEDEDEDEAGSELGEGE--------EEVGLSYLMKEEIQDEEDDDDYVEEG 239
EE +EE + DE EDE++ G EL + + GL L K+ E + + +
Sbjct: 494 EEGDEEGEGDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTPEQFGENLRDS 553
Query: 240 EEEEEEEE 247
+ E E+
Sbjct: 554 YQRHETEQ 561
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 68.2 bits (165), Expect = 7e-12
Identities = 36/95 (37%), Positives = 54/95 (56%)
Query: 172 EEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEED 231
E+ E++ PE EEEEEEEEEE+E+E+ +E+E G + + + + EI E++
Sbjct: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE 1400
Query: 232 DDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
D +++ EEEEEE+E E D EDD E
Sbjct: 1401 DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHME 1435
Score = 55.1 bits (131), Expect = 6e-08
Identities = 30/92 (32%), Positives = 50/92 (54%)
Query: 154 EAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGE 213
E + EEE++E+ +E++ EEEE + + + +E+EE E E ED A + E E
Sbjct: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411
Query: 214 EEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
EE E+ +++DD ++E E E+EE
Sbjct: 1412 EEEDEEPSHNEDHDADDEDDSHMESAEVEKEE 1443
Score = 53.1 bits (126), Expect = 2e-07
Identities = 25/47 (53%), Positives = 36/47 (76%), Gaps = 7/47 (14%)
Query: 158 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE 204
S+E +E+ +E+DEEEEE E EEEEE+EEEE+E+E+E+E+E
Sbjct: 1065 SKESSEEEEEEEDEEEEEEE-------EEEEEDEEEEEEEEEEEEEE 1104
Score = 52.0 bits (123), Expect = 5e-07
Identities = 25/51 (49%), Positives = 37/51 (72%), Gaps = 9/51 (17%)
Query: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS 207
+S EE++E+ DE++EEEEE EEEE+EEEEE+E+E+E+E+ S
Sbjct: 1067 ESSEEEEEEEDEEEEEEEE---------EEEEDEEEEEEEEEEEEEENIQS 1108
Score = 50.8 bits (120), Expect = 1e-06
Identities = 34/115 (29%), Positives = 63/115 (54%), Gaps = 21/115 (18%)
Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEE--ENEAG-----PPEGYEEEEEEEEE--------- 193
++D P+ EEE++E+ +E++EEEE E E G P+G + +E+EE E
Sbjct: 1344 EDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSA 1403
Query: 194 ----EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 244
+E+E+EDE+ + +E + ++E S++ E++ EE + +E E +E
Sbjct: 1404 RLDDHEEEEEEDEEPSHNEDHDADDEDD-SHMESAEVEKEELPRESFKEVLENQE 1457
Score = 49.3 bits (116), Expect = 4e-06
Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Query: 147 GFDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEE----DEDEDED 201
GF P++ E DE E+ +E E + P EEE +E E E+ +
Sbjct: 1268 GFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRRE 1327
Query: 202 EDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAED 261
E A E L+K E ++EE++++ EE EEE EEEEGG EK A+
Sbjct: 1328 ETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKS 1387
Query: 262 DGEEEDD 268
+EE +
Sbjct: 1388 QEKEEPE 1394
Score = 46.2 bits (108), Expect = 3e-05
Identities = 24/54 (44%), Positives = 33/54 (61%)
Query: 155 APDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
+P+S E G + +E +E E EEEEEEEEEE+EDE+E+E+E E
Sbjct: 1048 SPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE 1101
Score = 46.2 bits (108), Expect = 3e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 10/85 (11%)
Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
DG ++ E P+ E ++ DD EEEE EE+EE ED D D DED++
Sbjct: 1383 DGAKSQEKEEPEISTEKEDSARLDDHEEEE---------EEDEEPSHNEDHDAD-DEDDS 1432
Query: 206 GSELGEGEEEVGLSYLMKEEIQDEE 230
E E E+E KE ++++E
Sbjct: 1433 HMESAEVEKEELPRESFKEVLENQE 1457
Score = 45.8 bits (107), Expect = 4e-05
Identities = 25/67 (37%), Positives = 36/67 (53%)
Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
Q N+ S E G+ E E+ E EE+EEEEEEE+E+E+++E+E E
Sbjct: 1040 QSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099
Query: 210 GEGEEEV 216
E EE +
Sbjct: 1100 EEEEENI 1106
Score = 44.7 bits (104), Expect = 9e-05
Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 23/62 (37%)
Query: 186 EEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
+E EEEEE+EDE+E+E+E +EE++D+ EE EEEEEE
Sbjct: 1066 KESSEEEEEEEDEEEEEEE-----------------------EEEEEDEEEEEEEEEEEE 1102
Query: 246 EE 247
EE
Sbjct: 1103 EE 1104
Score = 44.3 bits (103), Expect = 1e-04
Identities = 23/55 (41%), Positives = 34/55 (61%), Gaps = 9/55 (16%)
Query: 141 QITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEED 195
Q+ L E+ E + EEE++E+ +E+++EEEE EEEEEEEEEE+
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE---------EEEEEEEEEEN 1105
Score = 38.1 bits (87), Expect = 0.008
Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
+E+ EA E E ++EE+E + + + + + + E
Sbjct: 999 EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
Query: 210 GEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
G+ L L KE ++EE+++D EEEEEEEE E+ + + E++ EEE+
Sbjct: 1059 GQ------LLELSKESSEEEEEEED-----EEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105
Score = 37.0 bits (84), Expect = 0.018
Identities = 14/34 (41%), Positives = 27/34 (79%), Gaps = 1/34 (2%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEEN-EAGPP 181
++E+ E + EE+++E+ +E++EEEEEN ++ PP
Sbjct: 1078 EEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111
Score = 35.8 bits (81), Expect = 0.040
Identities = 14/46 (30%), Positives = 31/46 (67%)
Query: 132 RESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENE 177
R + EL ++ + + ++++ E + EEE++++ +E++EEEEE E
Sbjct: 1058 RGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103
Score = 35.0 bits (79), Expect = 0.069
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 122 NCEITNLEDYRESIFELLQ-QITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180
+ E+ E RES E+L+ Q T+LD Q + P+ + D E + AG
Sbjct: 1436 SAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGD 1495
Query: 181 PEGYEEEEEEE---EEEDEDEDEDEDEAGSELGEG-----EEEVGLSYLMKEEIQDEEDD 232
PE E +EE E+ + + ++ E +E EG E + ++ Q+ +
Sbjct: 1496 PEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQ 1555
Query: 233 DDYVEEGEEEEE 244
DD ++ E +E
Sbjct: 1556 DDTFQDCAETQE 1567
Score = 33.5 bits (75), Expect = 0.20
Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL- 209
+D+E + EEED+E +D + ++ + E E E+EE E E + E +L
Sbjct: 1406 DDHE--EEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLN 1463
Query: 210 ---GEGEEE------VGLSYLMKEEIQDEEDDDDYVEEGEEEEEE-EEGGLRGEKRKRDA 259
G E V L+ E ++ D + V E +EE E+ + +K ++
Sbjct: 1464 VQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEV 1523
Query: 260 EDDGEE 265
+ + +E
Sbjct: 1524 DTEFKE 1529
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 67.4 bits (163), Expect = 1e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 25/139 (17%)
Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE-------------EEEEDE 196
++D+E +EED +EDDE E+ E G G ++E+E EEEE+E
Sbjct: 479 KDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEE 538
Query: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE---------EEEEEE 247
D++E+E+E E E EVG + L + ++EE++++ +EE E + EE
Sbjct: 539 DKEEEEEEEDEERREERAEVG-APLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEA 597
Query: 248 GGLRGEKRKRDAEDDGEEE 266
GG E + ED G ++
Sbjct: 598 GGASSE--EESGEDTGPQD 614
Score = 54.3 bits (129), Expect = 1e-07
Identities = 40/173 (23%), Positives = 74/173 (42%), Gaps = 52/173 (30%)
Query: 147 GFDQEDNEAPDSEEEDDED-----------------GDEDDEE--EEENEAGPPEGYEEE 187
G D ED+E + EEE++E+ G E+DE+ + + GP ++
Sbjct: 184 GHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGH 243
Query: 188 EEEEEEEDEDEDEDED-------------------EAGSELGEGEEEVGLSYLMKEEIQD 228
EE+++++D+D+D+D+D E ++ +G S+ + +D
Sbjct: 244 EEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEED 303
Query: 229 EEDDDDYVEE-------GEEEEEEEEGGLRGE-------KRKRDAEDDGEEED 267
+ DDDD E ++ +EE + GE R + D+ E+ED
Sbjct: 304 DNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDED 356
Score = 48.9 bits (115), Expect = 5e-06
Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 21/121 (17%)
Query: 146 DGFDQEDNE-----APDSEEEDDEDGDEDDEEEEEN------EAGPPEGYEEEEEEEEEE 194
D D+ED E + + EEE++ED +E++EEE+E E G P + EEEEEEE
Sbjct: 515 DQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEE 574
Query: 195 DEDEDEDEDE---AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLR 251
E +EDE + L EE G S ++E +D ++ +E + G L
Sbjct: 575 -EGLEEDEPRFTIIPNPLDRREEAGGAS------SEEESGEDTGPQDAQEYGNYQPGSLC 627
Query: 252 G 252
G
Sbjct: 628 G 628
Score = 46.6 bits (109), Expect = 2e-05
Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 21/128 (16%)
Query: 158 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED-------------- 203
S +++DED E G++ E++E EEE+E+E+E+E+
Sbjct: 159 SHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRG 218
Query: 204 ---EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAE 260
E ++ +G G S+ + +D++DDDD ++++++++ + + +
Sbjct: 219 HGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDD----DDDDDDDDDVSIEYRHQAHRHQ 274
Query: 261 DDGEEEDD 268
G EED+
Sbjct: 275 GHGIEEDE 282
Score = 45.8 bits (107), Expect = 4e-05
Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 28/148 (18%)
Query: 149 DQEDNEAPDSEE------------EDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDE 196
D++++E SE + ++D E++EEEEE E Y +
Sbjct: 162 DEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGS 221
Query: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDD-------------YVEEGEEEE 243
+EDED + G G ++ D++DDDD + G EE+
Sbjct: 222 EEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEED 281
Query: 244 EEEEGGLR---GEKRKRDAEDDGEEEDD 268
E+ G R R E+D ++DD
Sbjct: 282 EDVSDGHHHRDPSHRHRSHEEDDNDDDD 309
Score = 43.5 bits (101), Expect = 2e-04
Identities = 42/175 (24%), Positives = 73/175 (41%), Gaps = 66/175 (37%)
Query: 159 EEEDDEDGDED--------------DEEEEENE----------AGPPEGYEEEEEEEEEE 194
+EE+DED + DEEEEE E + P G++ +EE+ ++E
Sbjct: 350 DEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDE 409
Query: 195 DEDE----------DEDEDEAGSELGEG---------EEEVG------------------ 217
+ E E+++E +ELG +EE G
Sbjct: 410 YKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHT 469
Query: 218 ----LSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKR-KRDAEDDGEEED 267
S+L K++ ++E++ ++ EE++E E G +G RD ED+ +EE+
Sbjct: 470 VVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEE 524
Score = 42.7 bits (99), Expect = 3e-04
Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 41/139 (29%)
Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE-----------EEEEEDEDE 198
+ED++ D +++DD+D D E + G EE+E+ E++
Sbjct: 244 EEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEED 303
Query: 199 DEDEDEAGSELG-----------------EGEEEVGLSYLMKEEIQDEEDDDD------- 234
D D+D+ +E G GE + + +DEE+D+D
Sbjct: 304 DNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWH 363
Query: 235 ----YVEEG--EEEEEEEE 247
+V G +EEEEEEE
Sbjct: 364 QGPQHVHHGLVDEEEEEEE 382
Score = 29.6 bits (65), Expect = 2.9
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 26/107 (24%)
Query: 156 PDSEEEDDEDGDEDDEEEE--ENEAGPPEGYEEEEEEEEEEDED-------------EDE 200
P +D + GDE EE G G+ E+ E+ + +DE
Sbjct: 104 PGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDE 163
Query: 201 DEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
DEDE S ++++ + + +DD EGEE EEEEE
Sbjct: 164 DEDEVVSSEHH-------HHILRHGHRGHDGEDD---EGEE-EEEEE 199
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 67.0 bits (162), Expect = 2e-11
Identities = 44/140 (31%), Positives = 78/140 (55%), Gaps = 13/140 (9%)
Query: 137 ELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDE 196
E ++ T G +E A EE+D+ DE+D+ EE+ EAG +E+++E+ EED
Sbjct: 103 ENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG-----KEDKDEKGEEDG 157
Query: 197 DEDEDEDEAGSELGE------GEEEVGLSYLMKEEIQDEEDDDDYVE--EGEEEEEEEEG 248
ED++ +E G + E GE+ G KE+ +DE++++D E +G+E E+ +E
Sbjct: 158 KEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEK 217
Query: 249 GLRGEKRKRDAEDDGEEEDD 268
G + E + ++D +E +D
Sbjct: 218 GDKKEGKDVKVKEDEKERED 237
Score = 65.1 bits (157), Expect = 6e-11
Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 25/150 (16%)
Query: 127 NLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEE 186
N+ED E G +E A EE+D+ DE+D+ EE+ EAG +E
Sbjct: 104 NIEDATEK-----------GGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG-----KE 147
Query: 187 EEEEEEEEDEDEDEDEDEAGSELGE------GEEEVGLSYLMKEEIQDEEDDDDYVEEG- 239
+++E+ EED ED++ +E G + E GE+ G KE+ +DE++++D E G
Sbjct: 148 DKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD 207
Query: 240 --EEEEEEEEGGLRGEKRKRDAEDDGEEED 267
E E+ +E+G + K + ED+ E ED
Sbjct: 208 GKENEDGKEKGDKKEGKDVKVKEDEKERED 237
Score = 61.6 bits (148), Expect = 7e-10
Identities = 49/143 (34%), Positives = 76/143 (53%), Gaps = 28/143 (19%)
Query: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED-------- 197
D DQ + + +E+ DE G+ED +E++ G +G + +E+E+ ++ ED
Sbjct: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKN---GNEKGEDAKEKEDGKKGEDGKGNGEDG 189
Query: 198 ----EDEDEDEAGSELGEGEE-EVGLSYLMKEEIQDEEDDDDYVEEGEEEEE---EEEGG 249
EDE E+E E G+G+E E G KE+ +E D V+E E+E E E+EGG
Sbjct: 190 KEKGEDEKEEEDRKETGDGKENEDG-----KEKGDKKEGKDVKVKEDEKEREDGKEDEGG 244
Query: 250 LRGE--KRKRD--AEDDGEEEDD 268
E K K D E++G+EED+
Sbjct: 245 NEEEAGKEKEDLKEEEEGKEEDE 267
Score = 59.3 bits (142), Expect = 3e-09
Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 23/145 (15%)
Query: 129 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
EDY E+ +IT ++E E +EE+ ED E E++E A + EE
Sbjct: 74 EDYNENAKNGEAKITEAPASEKEIVEV---KEENIEDATEKGGEKKEAVAAE---VKNEE 127
Query: 189 EEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEG 248
E+++E++ED++E++ EAG E + + E +D ++D + E+GE+ +E+E+G
Sbjct: 128 EDQKEDEEDQNEEKGEAGKEDKDEKGE-----------EDGKEDKNGNEKGEDAKEKEDG 176
Query: 249 GL------RGEKRKRDAEDDGEEED 267
GE K ED+ EEED
Sbjct: 177 KKGEDGKGNGEDGKEKGEDEKEEED 201
Score = 55.5 bits (132), Expect = 5e-08
Identities = 36/109 (33%), Positives = 65/109 (59%), Gaps = 13/109 (11%)
Query: 146 DGFDQEDNEA--PDSEEEDDEDGDEDDEEE----EENEAGPPEGYEEEEEE---EEEEDE 196
DG ED + D +E+ +++ +E+D +E +ENE G +G ++E ++ +E+E E
Sbjct: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKE 234
Query: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
ED EDE G+E G+E+ L KEE + +E+D+ ++G++EE +
Sbjct: 235 REDGKEDEGGNEEEAGKEKEDL----KEEEEGKEEDEIKEDDGKKEEPQ 279
Score = 52.4 bits (124), Expect = 4e-07
Identities = 36/114 (31%), Positives = 65/114 (57%), Gaps = 15/114 (13%)
Query: 146 DGFDQEDNEAPDSEEEDDEDGDE--DDEEEEENEAGPPEGYEEEEEEEEEEDED------ 197
D ++ED + + + + EDG E +DE+EEE+ +G E E+ +E+ + ++
Sbjct: 169 DAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKV 228
Query: 198 -EDEDEDEAGSE-LGEGEEEVGLSYLMKEEIQDEED--DDDYVEEGEEEEEEEE 247
EDE E E G E G EEE G KE++++EE+ ++D ++E + ++EE +
Sbjct: 229 KEDEKEREDGKEDEGGNEEEAGKE---KEDLKEEEEGKEEDEIKEDDGKKEEPQ 279
Score = 45.4 bits (106), Expect = 5e-05
Identities = 30/103 (29%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
Query: 170 DEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE 229
+E+ EN E E+E E ++E+ ++A + GE +E V +EE Q E
Sbjct: 73 EEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKE 132
Query: 230 EDDDDYVEEGE--EEEEEEEGGLRGEKRKRDAE--DDGEEEDD 268
+++D E+GE +E+++E+G G++ K E +D +E++D
Sbjct: 133 DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 12/109 (11%)
Query: 158 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVG 217
+E + + +ED E +N E+E E E+ ED E G GE++
Sbjct: 64 AETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKG-----GEKKEA 118
Query: 218 LSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
++ +K E +D+++D EE++ EE+G E + E+DG+E+
Sbjct: 119 VAAEVKNEEEDQKED-------EEDQNEEKGEAGKEDKDEKGEEDGKED 160
Score = 36.2 bits (82), Expect = 0.031
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 159 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEE-EEEEEDEDEDEDEDEAGS 207
+E++ EDG ED+ EE E +EEEE +EE+E +++D ++E S
Sbjct: 231 DEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 66.6 bits (161), Expect = 2e-11
Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)
Query: 131 YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 190
Y+E I + +T L G + + + + + E+ DE+DE++E+ E+EEE
Sbjct: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 657
Query: 191 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 250
E++E+ D ED ++ E E E G E +D+ED+DD ++ E+E+ E EG
Sbjct: 658 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 712
Query: 251 RGEKRKRDAED 261
D+ D
Sbjct: 713 SSSSSSGDSSD 723
Score = 57.8 bits (138), Expect = 1e-08
Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 240
E E++EE+E++EDEDE+E++DE G +G + S + E DE E+DD+ ++ E
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698
Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267
+++E+E+ G + D + D
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 43.9 bits (102), Expect = 1e-04
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)
Query: 188 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 241
+ + E E++DE+ EDE+E E G+ E+ G S E +D E+G+E
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 686
Query: 242 EEEEEEGGLRGEKRKRDAEDDGEEEDD 268
EE++E + D EDD E+ED+
Sbjct: 687 NEEDDED-------EDDDEDDDEDEDN 706
Score = 38.1 bits (87), Expect = 0.008
Identities = 14/49 (28%), Positives = 28/49 (57%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 197
D+ ++ + E+++DED DEDD+E+E+NE+ + + D +
Sbjct: 679 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
Score = 35.0 bits (79), Expect = 0.069
Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)
Query: 152 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
++E+ D +E +++D DEDD+E+++ E+E+ E E D + S+
Sbjct: 678 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 725
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 66.6 bits (161), Expect = 2e-11
Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)
Query: 131 YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 190
Y+E I + +T L G + + + + + E+ DE+DE++E+ E+EEE
Sbjct: 608 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 657
Query: 191 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 250
E++E+ D ED ++ E E E G E +D+ED+DD ++ E+E+ E EG
Sbjct: 658 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 712
Query: 251 RGEKRKRDAED 261
D+ D
Sbjct: 713 SSSSSSGDSSD 723
Score = 57.8 bits (138), Expect = 1e-08
Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 240
E E++EE+E++EDEDE+E++DE G +G + S + E DE E+DD+ ++ E
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698
Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267
+++E+E+ G + D + D
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 43.9 bits (102), Expect = 1e-04
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)
Query: 188 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 241
+ + E E++DE+ EDE+E E G+ E+ G S E +D E+G+E
Sbjct: 635 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 686
Query: 242 EEEEEEGGLRGEKRKRDAEDDGEEEDD 268
EE++E + D EDD E+ED+
Sbjct: 687 NEEDDED-------EDDDEDDDEDEDN 706
Score = 38.1 bits (87), Expect = 0.008
Identities = 14/49 (28%), Positives = 28/49 (57%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 197
D+ ++ + E+++DED DEDD+E+E+NE+ + + D +
Sbjct: 679 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
Score = 35.0 bits (79), Expect = 0.069
Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)
Query: 152 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
++E+ D +E +++D DEDD+E+++ E+E+ E E D + S+
Sbjct: 678 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 725
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 66.6 bits (161), Expect = 2e-11
Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 15/131 (11%)
Query: 131 YRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEE 190
Y+E I + +T L G + + + + + E+ DE+DE++E+ E+EEE
Sbjct: 645 YKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDED----------EDEEE 694
Query: 191 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 250
E++E+ D ED ++ E E E G E +D+ED+DD ++ E+E+ E EG
Sbjct: 695 EDDENGDSSEDGGDSSESSSEDESEDG-----DENEEDDEDEDDDEDDDEDEDNESEGSS 749
Query: 251 RGEKRKRDAED 261
D+ D
Sbjct: 750 SSSSSSGDSSD 760
Score = 57.8 bits (138), Expect = 1e-08
Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDE-EDDDDYVEEGE 240
E E++EE+E++EDEDE+E++DE G +G + S + E DE E+DD+ ++ E
Sbjct: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 735
Query: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267
+++E+E+ G + D + D
Sbjct: 736 DDDEDEDNESEGSSSSSSSSGDSSDSD 762
Score = 43.9 bits (102), Expect = 1e-04
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 21/87 (24%)
Query: 188 EEEEEEEDEDED------EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 241
+ + E E++DE+ EDE+E E G+ E+ G S E +D E+G+E
Sbjct: 672 QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS--------SESSSEDESEDGDE 723
Query: 242 EEEEEEGGLRGEKRKRDAEDDGEEEDD 268
EE++E + D EDD E+ED+
Sbjct: 724 NEEDDED-------EDDDEDDDEDEDN 743
Score = 38.1 bits (87), Expect = 0.008
Identities = 14/49 (28%), Positives = 28/49 (57%)
Query: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDED 197
D+ ++ + E+++DED DEDD+E+E+NE+ + + D +
Sbjct: 716 DESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
Score = 35.0 bits (79), Expect = 0.069
Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 9/57 (15%)
Query: 152 DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
++E+ D +E +++D DEDD+E+++ E+E+ E E D + S+
Sbjct: 715 EDESEDGDENEEDDEDEDDDEDDD---------EDEDNESEGSSSSSSSSGDSSDSD 762
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 66.2 bits (160), Expect = 3e-11
Identities = 36/125 (28%), Positives = 74/125 (59%), Gaps = 2/125 (1%)
Query: 124 EITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEE-DDEDGDEDDEEEEENEAGPPE 182
E+ + E + E + LL ++ + E+ E + EEE ++E+ E++EE +E E G +
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK 2278
Query: 183 GYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE 242
E+EEEE++++ +++ ++E + E+ E +EE+ +S E + DEE++++ EE
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI-MSEEETESLSDEEEEEESCSLEEEV 2337
Query: 243 EEEEE 247
+ E+E
Sbjct: 2338 DREKE 2342
Score = 58.5 bits (140), Expect = 6e-09
Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 11/146 (7%)
Query: 132 RESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEE 191
+E + ++ + F +E D E+ + E++EE EE E E EEEEE
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269
Query: 192 EEEDEDED-----EDEDEAGSELGEGEEEVGLS---YLMKEEIQDEEDDDDYVEEGEEEE 243
+EE+E E+ E+E++ + + +EEV + KEEI EE+ + +E EEEE
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329
Query: 244 E---EEEGGLRGEKRKRDAEDDGEEE 266
EEE E K++ + +E+
Sbjct: 2330 SCSLEEEVDREKEILKKEKQFKLQEQ 2355
Score = 50.8 bits (120), Expect = 1e-06
Identities = 37/142 (26%), Positives = 75/142 (52%), Gaps = 14/142 (9%)
Query: 128 LEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDE-EEEENEAGPPEGYEE 186
L+D E E + I +L ++ EA ++ ++ + DE E EE+ + E +
Sbjct: 2176 LDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLD 2235
Query: 187 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 246
E E++E +E+E+ +E E E E +EE+++EE++ EEGEE++ E+
Sbjct: 2236 ELEKQESLSSEEEEEREE------EEERE-------EEEVREEEEERKEEEEGEEKQVEK 2282
Query: 247 EGGLRGEKRKRDAEDDGEEEDD 268
E + +K+K +++ +E+++
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEE 2304
Score = 32.7 bits (73), Expect = 0.34
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 29/128 (22%)
Query: 158 SEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDE-------------DEDE 204
S+E+ +D +E EEE + EG E+E++ EE+ ++E ++
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSR----EGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR 1588
Query: 205 AGSELGEGEEEVGLSYLMKEEIQDE-----------EDDDDYVE-EGEEEEEEEEGGLRG 252
A E +EE L+ ++ Q+E +DD + + EG+ ++EE RG
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRG 1648
Query: 253 EKRKRDAE 260
EK ++AE
Sbjct: 1649 EKLSQEAE 1656
Score = 32.0 bits (71), Expect = 0.58
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
Query: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-GYEEEEEEEEE----EDEDEDEDEDE 204
Q+ E P E+ D E +E EE E E ++EEE +EE E++ + +E+E
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754
Query: 205 AGSELGE--GEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 244
A + E EEE L+ + IQ++E + E+ EEEE
Sbjct: 1755 ALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796
Score = 29.3 bits (64), Expect = 3.8
Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 171 EEEEENEAGPPEGYEEEEEEEEEE---DEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQ 227
EEE+ ++AG EEE +E+++ +E + E+ S+ E + + ++EE+
Sbjct: 1492 EEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVS 1551
Query: 228 DE-EDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267
E E+ + V E + +EE R +++ AE +E+
Sbjct: 1552 REGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 66.2 bits (160), Expect = 3e-11
Identities = 48/147 (32%), Positives = 69/147 (46%), Gaps = 19/147 (12%)
Query: 129 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
ED +ES+ E + ++E+ + EEEDD+D D DD +E EN+ E E
Sbjct: 1035 EDEKESLSEEQEST------EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088
Query: 189 EEEEEEDEDE------DEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEE 242
++E + DE+E + E + SE E E S + ED+++ V EEE
Sbjct: 1089 KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSS---ESSPSSSEDEEEVVAREEEE 1145
Query: 243 EEEEEGGLRGEKR----KRDAEDDGEE 265
EEEEE + E D E DGEE
Sbjct: 1146 EEEEEEMVAEESMASAGPEDFEQDGEE 1172
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
Query: 152 DNEAPDSEEEDDED-GDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 210
D E +SE E D D D E + + G G E D +EDE E+ SE
Sbjct: 988 DEEDEESERERDRDMADTPCELAKRDPKGV--GVRRRPARPLELDSGGEEDEKESLSEEQ 1045
Query: 211 EGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEE 265
E EE +EE ++++DDDD + E E ++E+ L K + + D EE
Sbjct: 1046 ESTEEE--EEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098
Score = 42.7 bits (99), Expect = 3e-04
Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 36/119 (30%)
Query: 181 PEGYEEEEEEEEEEDEDED---------------------------------EDEDEAGS 207
P +EE+EE E + D D EDE E+ S
Sbjct: 983 PSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLS 1042
Query: 208 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEE 266
E E EE +EE ++E+DDDD ++ +E E ++E E ++D D EEE
Sbjct: 1043 EEQESTEE---EEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098
Score = 39.3 bits (90), Expect = 0.004
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 187 EEEEEEEEDEDEDEDEDEAGSELGEGEEE-VGLSYLMKEEIQ----DEEDDDDYVEEGEE 241
+EE+EE E E D D + EL + + + VG+ ++ EED+ + + E +E
Sbjct: 988 DEEDEESERE-RDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQE 1046
Query: 242 EEEEEEGGLRGEKRKRDAEDDGEEEDD 268
EEEE E+ + D +DD ++ D+
Sbjct: 1047 STEEEEEAEEEEEEEDDDDDDSDDRDE 1073
Score = 34.7 bits (78), Expect = 0.090
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 72/174 (41%)
Query: 149 DQEDNEAPDSEEEDDED-----------GDEDDEE-----------------------EE 174
D +D++ D E DDED GD D+EE E
Sbjct: 1064 DDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFES 1123
Query: 175 ENEAGPPEGY--------EEEEEEEEEE-----------DEDEDEDEDEAGSELGEGEEE 215
+E+ P EEEEEEEEEE ED ++D +EA L G
Sbjct: 1124 SSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAA--LAPGAPA 1181
Query: 216 VGLSYLMKEEIQDEED-----------DDDYVEEGEEE-----EEEEEGGLRGE 253
V S M+EE+ E + D+ + G EE E EE GL E
Sbjct: 1182 VD-SLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQE 1234
>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
Length = 466
Score = 66.2 bits (160), Expect = 3e-11
Identities = 57/239 (23%), Positives = 115/239 (48%), Gaps = 4/239 (1%)
Query: 12 RNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLEL 71
RN + L+ EIE L K L + ++ + + ++ +++KL+KLE
Sbjct: 11 RNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEY 70
Query: 72 SDNIISGGLEVLA--EKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLE 129
N+ +E + E C L L+L+ N I +LS+++ LQ+ +LK L L + +
Sbjct: 71 L-NLALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFD 129
Query: 130 DYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE 189
YRE + L Q+ +LDG + E +E + ++ + E+E+++ + EE +
Sbjct: 130 HYREFVVATLPQLKWLDGKEIEPSERIKALQDYSVIEPQIREQEKDHCLKRAKLKEEAQR 189
Query: 190 EEEEEDEDEDEDEDEAGSELGEGEEEVGLSYL-MKEEIQDEEDDDDYVEEGEEEEEEEE 247
+ +EED++ED+ + + LS L K+ +Q + ++ ++ + E++ E
Sbjct: 190 KHQEEDKNEDKRSNAGFDGRWYTDINATLSSLESKDHLQAPDTEEHNTKKLDNSEDDLE 248
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 65.5 bits (158), Expect = 5e-11
Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 12/118 (10%)
Query: 132 RESIFELLQQITYLDGFDQEDNE--APDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE 189
+E+++ +Q + + E+N+ AP EE++E ++D+EE ++ E EEEEE
Sbjct: 247 QETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEE 306
Query: 190 --EEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
+EEEE EDE+E+E E + EGEEE L +EE+++EE + +EE E+ EE
Sbjct: 307 VEDEEEEVEDEEEEEVEEAEYVEEGEEE-----LEEEELEEEE---EVLEENEQRGEE 356
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Query: 148 FDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDEDEAG 206
+DQE +A ++ EE++E DE++E E+E E E Y EE EEE EE+E E+E+E
Sbjct: 290 YDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
Query: 207 SELGEGEEEVGLSYLMKEEIQDEEDDDDYV 236
+E E + L + ++ EE ++++
Sbjct: 350 NEQRGEEFHLPLEMPLSIFVEAEEKRENFI 379
Score = 41.6 bits (96), Expect = 7e-04
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 129 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
E+Y + + + + + + E+ E D EEE+ E+ + +E EEE EEEE
Sbjct: 288 EEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE--------LEEEE 339
Query: 189 EEEEEEDEDEDEDEDE 204
EEEEE +E+E E
Sbjct: 340 LEEEEEVLEENEQRGE 355
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 65.1 bits (157), Expect = 6e-11
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)
Query: 149 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 204
D ED+ SEEED E DG+E + +EE A E EE E+EEEEEE+E+ DE+E+E
Sbjct: 3 DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60
Query: 205 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
+ + G L + ++ DE +D+D E+G E+ E+E
Sbjct: 61 EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103
Score = 54.3 bits (129), Expect = 1e-07
Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 205
E E P+ EEE++E+ + D+EEEEE++ PP+ G+ +E + ++E EDED+ ED
Sbjct: 37 EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94
Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 262
G E++ L KEEI+ D+ + +E+ G R + RD ++
Sbjct: 95 ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135
Score = 47.0 bits (110), Expect = 2e-05
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)
Query: 184 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 243
+ EEE+ E D +E E ++E S G +E EE +DEE++++ EE +EE
Sbjct: 9 FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57
Query: 244 EEEEGGLRGEKRKR---------DAEDDGEEED 267
EEEE R K+ R D +D+ E+ED
Sbjct: 58 EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90
Score = 33.5 bits (75), Expect = 0.20
Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Query: 229 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 268
EE+D + +GEE E +EE G +++ + ED+ EEE++
Sbjct: 11 EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51
Score = 32.7 bits (73), Expect = 0.34
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)
Query: 194 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
+ ED + E+E +GEE E D++ G E+EEE E E
Sbjct: 3 DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49
Query: 254 KRKRDAEDDGEEEDD 268
+ + E++ EE+DD
Sbjct: 50 EEEEYDEEEEEEDDD 64
>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 65.1 bits (157), Expect = 6e-11
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)
Query: 149 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 204
D ED+ SEEED E DG+E + +EE A E EE E+EEEEEE+E+ DE+E+E
Sbjct: 3 DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60
Query: 205 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
+ + G L + ++ DE +D+D E+G E+ E+E
Sbjct: 61 EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103
Score = 54.3 bits (129), Expect = 1e-07
Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 205
E E P+ EEE++E+ + D+EEEEE++ PP+ G+ +E + ++E EDED+ ED
Sbjct: 37 EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94
Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 262
G E++ L KEEI+ D+ + +E+ G R + RD ++
Sbjct: 95 ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135
Score = 47.0 bits (110), Expect = 2e-05
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)
Query: 184 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 243
+ EEE+ E D +E E ++E S G +E EE +DEE++++ EE +EE
Sbjct: 9 FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57
Query: 244 EEEEGGLRGEKRKR---------DAEDDGEEED 267
EEEE R K+ R D +D+ E+ED
Sbjct: 58 EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90
Score = 33.5 bits (75), Expect = 0.20
Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Query: 229 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 268
EE+D + +GEE E +EE G +++ + ED+ EEE++
Sbjct: 11 EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51
Score = 32.7 bits (73), Expect = 0.34
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)
Query: 194 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
+ ED + E+E +GEE E D++ G E+EEE E E
Sbjct: 3 DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49
Query: 254 KRKRDAEDDGEEEDD 268
+ + E++ EE+DD
Sbjct: 50 EEEEYDEEEEEEDDD 64
>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 65.1 bits (157), Expect = 6e-11
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 6/103 (5%)
Query: 149 DQEDNEAPDSEEEDDE---DGDEDDEEEEENEAGPPEGYEE-EEEEEEEEDEDEDEDEDE 204
D ED+ SEEED E DG+E + +EE A E EE E+EEEEEE+E+ DE+E+E
Sbjct: 3 DSEDSNF--SEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEE 60
Query: 205 AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
+ + G L + ++ DE +D+D E+G E+ E+E
Sbjct: 61 EDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKE 103
Score = 54.3 bits (129), Expect = 1e-07
Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 23/117 (19%)
Query: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-----GYEEEEEEEEEEDEDEDEDEDEA 205
E E P+ EEE++E+ + D+EEEEE++ PP+ G+ +E + ++E EDED+ ED
Sbjct: 37 EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWED-- 94
Query: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 262
G E++ L KEEI+ D+ + +E+ G R + RD ++
Sbjct: 95 ------GAEDI----LEKEEIEASNIDNVVL------DEDRSGARRLQNLWRDQREE 135
Score = 47.0 bits (110), Expect = 2e-05
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)
Query: 184 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 243
+ EEE+ E D +E E ++E S G +E EE +DEE++++ EE +EE
Sbjct: 9 FSEEEDSERSSDGEEAEVDEERRSAAGSEKE---------EEPEDEEEEEE--EEEYDEE 57
Query: 244 EEEEGGLRGEKRKR---------DAEDDGEEED 267
EEEE R K+ R D +D+ E+ED
Sbjct: 58 EEEEDDDRPPKKPRHGGFILDEADVDDEYEDED 90
Score = 33.5 bits (75), Expect = 0.20
Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Query: 229 EEDDDDYVEEGEEEE-EEEEGGLRGEKRKRDAEDDGEEEDD 268
EE+D + +GEE E +EE G +++ + ED+ EEE++
Sbjct: 11 EEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEE 51
Score = 32.7 bits (73), Expect = 0.34
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 13/75 (17%)
Query: 194 EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
+ ED + E+E +GEE E D++ G E+EEE E E
Sbjct: 3 DSEDSNFSEEEDSERSSDGEEA-------------EVDEERRSAAGSEKEEEPEDEEEEE 49
Query: 254 KRKRDAEDDGEEEDD 268
+ + E++ EE+DD
Sbjct: 50 EEEEYDEEEEEEDDD 64
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.130 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,480,559
Number of Sequences: 37866
Number of extensions: 835467
Number of successful extensions: 67601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1408
Number of HSP's successfully gapped in prelim test: 724
Number of HSP's that attempted gapping in prelim test: 8712
Number of HSP's gapped (non-prelim): 21067
length of query: 268
length of database: 18,247,518
effective HSP length: 100
effective length of query: 168
effective length of database: 14,460,918
effective search space: 2429434224
effective search space used: 2429434224
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.