Guide to the Human Genome
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Search of human proteins with 60302875

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|60302875 shugoshin-like 1 isoform A1 [Homo sapiens]
         (527 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|60302875 shugoshin-like 1 isoform A1 [Homo sapiens]               1054   0.0  
gi|60302870 shugoshin-like 1 isoform A2 [Homo sapiens]               1043   0.0  
gi|60302877 shugoshin-like 1 isoform B1 [Homo sapiens]                350   2e-96
gi|60302873 shugoshin-like 1 isoform B2 [Homo sapiens]                350   2e-96
gi|60302879 shugoshin-like 1 isoform C1 [Homo sapiens]                315   5e-86
gi|24308448 shugoshin-like 1 isoform C2 [Homo sapiens]                315   5e-86
gi|55741677 SET domain containing 1A [Homo sapiens]                    47   6e-05
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]            43   6e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    43   8e-04
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    43   8e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    42   0.001
gi|38569484 kinesin family member 21A [Homo sapiens]                   42   0.001
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    42   0.002
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    41   0.002
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        41   0.002
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    41   0.003
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    41   0.003
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            40   0.004
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            40   0.004
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         40   0.004
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         40   0.004
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     40   0.005
gi|21361684 G patch domain containing 1 [Homo sapiens]                 40   0.005
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              40   0.005
gi|87299628 biorientation of chromosomes in cell division 1-like...    40   0.007
gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]      40   0.007
gi|118766347 zinc finger CCCH-type domain containing 6 [Homo sap...    40   0.007
gi|17978469 cyclin T2 isoform b [Homo sapiens]                         39   0.009
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  39   0.009
gi|148839362 LSM14 homolog B [Homo sapiens]                            39   0.009

>gi|60302875 shugoshin-like 1 isoform A1 [Homo sapiens]
          Length = 527

 Score = 1054 bits (2725), Expect = 0.0
 Identities = 527/527 (100%), Positives = 527/527 (100%)

Query: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60
           MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN
Sbjct: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60

Query: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120
           NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS
Sbjct: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120

Query: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKS 180
           GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKS
Sbjct: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKS 180

Query: 181 TDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPEN 240
           TDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPEN
Sbjct: 181 TDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPEN 240

Query: 241 VQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANR 300
           VQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANR
Sbjct: 241 VQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANR 300

Query: 301 RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREE 360
           RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREE
Sbjct: 301 RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREE 360

Query: 361 NNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGS 420
           NNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGS
Sbjct: 361 NNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGS 420

Query: 421 KPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTA 480
           KPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTA
Sbjct: 421 KPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTA 480

Query: 481 SVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ 527
           SVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ
Sbjct: 481 SVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ 527


>gi|60302870 shugoshin-like 1 isoform A2 [Homo sapiens]
          Length = 561

 Score = 1043 bits (2698), Expect = 0.0
 Identities = 521/526 (99%), Positives = 523/526 (99%)

Query: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60
           MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN
Sbjct: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60

Query: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120
           NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS
Sbjct: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120

Query: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKS 180
           GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKS
Sbjct: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKS 180

Query: 181 TDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPEN 240
           TDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPEN
Sbjct: 181 TDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPEN 240

Query: 241 VQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANR 300
           VQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANR
Sbjct: 241 VQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANR 300

Query: 301 RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREE 360
           RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREE
Sbjct: 301 RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREE 360

Query: 361 NNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGS 420
           NNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGS
Sbjct: 361 NNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGS 420

Query: 421 KPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTA 480
           KPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTA
Sbjct: 421 KPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTA 480

Query: 481 SVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQI 526
           SVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKK   ++
Sbjct: 481 SVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEV 526


>gi|60302877 shugoshin-like 1 isoform B1 [Homo sapiens]
          Length = 275

 Score =  350 bits (897), Expect = 2e-96
 Identities = 176/181 (97%), Positives = 176/181 (97%)

Query: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60
           MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN
Sbjct: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60

Query: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120
           NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS
Sbjct: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120

Query: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKS 180
           GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDS     
Sbjct: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSATPPE 180

Query: 181 T 181
           T
Sbjct: 181 T 181



 Score =  199 bits (507), Expect = 4e-51
 Identities = 99/101 (98%), Positives = 100/101 (99%)

Query: 427 TTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKE 486
           + TPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKE
Sbjct: 175 SATPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKE 234

Query: 487 PTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ 527
           PTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ
Sbjct: 235 PTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ 275


>gi|60302873 shugoshin-like 1 isoform B2 [Homo sapiens]
          Length = 309

 Score =  350 bits (897), Expect = 2e-96
 Identities = 176/181 (97%), Positives = 176/181 (97%)

Query: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60
           MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN
Sbjct: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60

Query: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120
           NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS
Sbjct: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120

Query: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKS 180
           GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDS     
Sbjct: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSATPPE 180

Query: 181 T 181
           T
Sbjct: 181 T 181



 Score =  189 bits (480), Expect = 5e-48
 Identities = 93/100 (93%), Positives = 96/100 (96%)

Query: 427 TTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKE 486
           + TPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKE
Sbjct: 175 SATPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKE 234

Query: 487 PTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQI 526
           PTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKK   ++
Sbjct: 235 PTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEV 274


>gi|60302879 shugoshin-like 1 isoform C1 [Homo sapiens]
          Length = 258

 Score =  315 bits (808), Expect = 5e-86
 Identities = 160/166 (96%), Positives = 160/166 (96%)

Query: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60
           MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN
Sbjct: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60

Query: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120
           NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS
Sbjct: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120

Query: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQ 166
           GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIE   P   Q
Sbjct: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEATPPETQQ 166



 Score =  201 bits (511), Expect = 1e-51
 Identities = 102/115 (88%), Positives = 104/115 (90%)

Query: 413 DEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVA 472
           +E E  G   +     TPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVA
Sbjct: 144 EETELPGQGESFQIEATPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVA 203

Query: 473 LPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ 527
           LPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ
Sbjct: 204 LPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQIQ 258


>gi|24308448 shugoshin-like 1 isoform C2 [Homo sapiens]
          Length = 292

 Score =  315 bits (808), Expect = 5e-86
 Identities = 160/166 (96%), Positives = 160/166 (96%)

Query: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60
           MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN
Sbjct: 1   MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDN 60

Query: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120
           NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS
Sbjct: 61  NKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSS 120

Query: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQ 166
           GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIE   P   Q
Sbjct: 121 GMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEATPPETQQ 166



 Score =  191 bits (484), Expect = 2e-48
 Identities = 96/114 (84%), Positives = 100/114 (87%)

Query: 413 DEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVA 472
           +E E  G   +     TPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVA
Sbjct: 144 EETELPGQGESFQIEATPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVA 203

Query: 473 LPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQI 526
           LPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKK   ++
Sbjct: 204 LPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEV 257


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 5/172 (2%)

Query: 261  QPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTV 320
            +P T  +  ED  E + E  +  +  T+  KR+E+R   + K  R S   +++ E     
Sbjct: 913  RPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGK-HRKSFALDSEGEEASQE 971

Query: 321  PQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSL-CESSGSGDDSD 379
               +  +     D  + + EE V  T    +VS+  + E ++ S+ SL  +S G  D + 
Sbjct: 972  SSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTS 1031

Query: 380  DLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPP 431
            D          + +S+S    +   +  + + + E E E  +P   P+ +PP
Sbjct: 1032 D---SESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPP 1080


>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 170

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 24/122 (19%)

Query: 213 TSHLAGKSFEFERVGFLDPLVNMHIPENVQHNACQWSKDQVNLSPKLIQPGTFTKTKEDI 272
           T  L GK F    + F D   ++H+P    H   Q                     +E+ 
Sbjct: 70  THRLKGKIFHLISIAFCDAGPSLHLP---LHGLPQ---------------------REEK 105

Query: 273 LESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSN 332
            E + E+ K K++  +++K+++K+K  ++K K+  + ++ K + K+   +KK  K   + 
Sbjct: 106 KEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNE 165

Query: 333 DA 334
            A
Sbjct: 166 GA 167


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 51/242 (21%), Positives = 101/242 (41%), Gaps = 16/242 (6%)

Query: 250 KDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKY 309
           KD+++ S K     T    K  + +S S++++S +   +E+ R+E+   +  K +  S  
Sbjct: 144 KDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH-KEKTRKERELKSGHKDRSKSHR 202

Query: 310 KENKSENKKTV---------PQKKMHKSVSSNDAYN-FNLEEGVHLTPFRQKVSNDSNRE 359
           K    ++ KTV         P +K   S   +D+ +  +  +   L+P R   S++ +  
Sbjct: 203 KRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSY 262

Query: 360 ENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEG 419
           + +    S  +S          Y  + +   +P S   R V+    +R+  Y    E  G
Sbjct: 263 KKSPGSTSRRQSVSPPYKEPSAYQSSTR-SPSPYSRRQRSVSPYSRRRSSSY----ERSG 317

Query: 420 SKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCT 479
           S   ++P+        SP LS + ++   L     ++  S SP  ++ S + +  KR  +
Sbjct: 318 SYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSS 377

Query: 480 AS 481
            S
Sbjct: 378 RS 379



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 36/144 (25%), Positives = 53/144 (36%), Gaps = 26/144 (18%)

Query: 301 RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNR-- 358
           RK     + K++  E+KK     K+ KS    +  N        +T    +V N S+   
Sbjct: 429 RKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVN--------VTHLNTEVKNSSDTGK 480

Query: 359 ---EENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEK 415
              +EN+E  +     +    DS  + L         T  S++    PL           
Sbjct: 481 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLP---------- 530

Query: 416 ETEGSKPTKTPTTTPPETQQSPHL 439
            T  S P   PTTTPP   Q+P L
Sbjct: 531 -TIASPPPPLPTTTPP--PQTPPL 551


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 51/242 (21%), Positives = 101/242 (41%), Gaps = 16/242 (6%)

Query: 250 KDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKY 309
           KD+++ S K     T    K  + +S S++++S +   +E+ R+E+   +  K +  S  
Sbjct: 144 KDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH-KEKTRKERELKSGHKDRSKSHR 202

Query: 310 KENKSENKKTV---------PQKKMHKSVSSNDAYN-FNLEEGVHLTPFRQKVSNDSNRE 359
           K    ++ KTV         P +K   S   +D+ +  +  +   L+P R   S++ +  
Sbjct: 203 KRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSY 262

Query: 360 ENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEG 419
           + +    S  +S          Y  + +   +P S   R V+    +R+  Y    E  G
Sbjct: 263 KKSPGSTSRRQSVSPPYKEPSAYQSSTR-SPSPYSRRQRSVSPYSRRRSSSY----ERSG 317

Query: 420 SKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCT 479
           S   ++P+        SP LS + ++   L     ++  S SP  ++ S + +  KR  +
Sbjct: 318 SYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSS 377

Query: 480 AS 481
            S
Sbjct: 378 RS 379



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 36/144 (25%), Positives = 53/144 (36%), Gaps = 26/144 (18%)

Query: 301 RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNR-- 358
           RK     + K++  E+KK     K+ KS    +  N        +T    +V N S+   
Sbjct: 429 RKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVN--------VTHLNTEVKNSSDTGK 480

Query: 359 ---EENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEK 415
              +EN+E  +     +    DS  + L         T  S++    PL           
Sbjct: 481 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLP---------- 530

Query: 416 ETEGSKPTKTPTTTPPETQQSPHL 439
            T  S P   PTTTPP   Q+P L
Sbjct: 531 -TIASPPPPLPTTTPP--PQTPPL 551


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 24/100 (24%), Positives = 45/100 (45%)

Query: 266 TKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKM 325
           T+  E+  E + ++ K K++  ++RK +EK+K  +   KR  K +E K   +K   +K+ 
Sbjct: 13  TEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEE 72

Query: 326 HKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESE 365
            +     +      EE       R+K      R+E  E +
Sbjct: 73  EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 20/99 (20%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           K K+   E   E  ++++ + +E KR+EKRK  R++ ++  K KE +   +K   +KK  
Sbjct: 4   KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63

Query: 327 KSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESE 365
           +                     R+K   +  REE  E E
Sbjct: 64  RK--------------------RKKKKEEEEREEEEEEE 82



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 18/61 (29%), Positives = 33/61 (54%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           K K    + + E+ + ++ + +E++ EEK +  RRK K+  + KE + E KK   +K   
Sbjct: 63  KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122

Query: 327 K 327
           K
Sbjct: 123 K 123


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 7/80 (8%)

Query: 300 RRKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNRE 359
           +RK KR  K    K +N  T  +KK  K VS  +     +EE        Q+VS+  + E
Sbjct: 549 KRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEES-------QEVSDHEDEE 601

Query: 360 ENNESEVSLCESSGSGDDSD 379
           E  E E    +   S D+SD
Sbjct: 602 EEEEEEEDDIDGGESSDESD 621


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 42/207 (20%), Positives = 90/207 (43%), Gaps = 22/207 (10%)

Query: 269 KEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSK--YKENKSENKKTVPQKKMH 326
           K+D  +SK++  KS + D +    + + K + +K K+  K   K++K ++KK   +K   
Sbjct: 423 KKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAE 482

Query: 327 KSVSSND-AYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSG---------- 375
            +   +D     + +        ++ +  D+ R++   ++    ESS +G          
Sbjct: 483 STEMESDLELKKDKKHSKEKKGSKKDIKKDA-RKDTESTDAEFDESSKTGFKTSTKIKGS 541

Query: 376 --DDSDDLYLPTC--KYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPP 431
             +  + LY P    K  ++  ++++  +    +KR  + + +K T   K  K  T   P
Sbjct: 542 DTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVP 601

Query: 432 ETQQSPHLSLKDITNVSLYPVVKIRRL 458
            +++ P L   + +     P  K+RRL
Sbjct: 602 PSREKPPLPACEPS----LPSPKVRRL 624



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 41/173 (23%), Positives = 65/173 (37%), Gaps = 25/173 (14%)

Query: 275 SKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSN-- 332
           S +   +SKQ   ++ KR+ +      KS   ++  +    + +T P+ +  K+VS N  
Sbjct: 137 SYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCS 196

Query: 333 -----DAYN--------FNLEEGVHLTPFRQKVSNDSNRE--ENNESEVSLCESSGSGDD 377
                D+ N         + +        R K SND   E    N   V      G  DD
Sbjct: 197 QKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDD 256

Query: 378 SD---DLYLPTCKYIQNPTSNSD---RPVTRPLAKRALKYTDEKETEGSKPTK 424
                D +L    Y QN + N        T+   K+  K + + E+E SK  K
Sbjct: 257 ESINFDAWLR--NYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAK 307


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 21/67 (31%), Positives = 41/67 (61%), Gaps = 2/67 (2%)

Query: 252 QVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKE 311
           + + SP+   P    K+K+   + K ++ K K+RD +++K +EK+K+ + K K+  K KE
Sbjct: 825 ETSKSPEKDVPMVEKKSKKP--KKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKE 882

Query: 312 NKSENKK 318
            +++ KK
Sbjct: 883 ERTKGKK 889



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 17/54 (31%), Positives = 32/54 (59%)

Query: 274 ESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHK 327
           +SK  + K K+   +ER +E+K++  ++KS +  K K  K + ++T  +KK  K
Sbjct: 840 KSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKK 893



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 41/198 (20%), Positives = 75/198 (37%), Gaps = 27/198 (13%)

Query: 252 QVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKE 311
           Q++LS  L  PG     +   LE +    +  ++D + +KR+EK K  +R+   +     
Sbjct: 706 QIDLSVPLKVPGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLP---- 761

Query: 312 NKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCES 371
               ++   P +++       D     + E    +    K  ND  R  + + +  L +S
Sbjct: 762 -TESDEDIAPAQQV-------DIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADS 813

Query: 372 SGSGDDSDDLYLPTCKYIQNPTSNS---DRPVTRPLAKRALKYT---DEKETEGSKPTKT 425
                      LP  K+    TS S   D P+    +K+  K      EKE +  K  + 
Sbjct: 814 E---------KLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEK 864

Query: 426 PTTTPPETQQSPHLSLKD 443
                P+ ++  H   K+
Sbjct: 865 EKKKSPKPKKKKHRKEKE 882


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 64/321 (19%), Positives = 113/321 (35%), Gaps = 46/321 (14%)

Query: 124 PNSD--DSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKST 181
           PN D  D  R   V +L  + LEE       E  QI++++ T     L  D + G  + T
Sbjct: 53  PNPDILDHERKRRV-ELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEET 111

Query: 182 DNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPENV 241
               P         + +     +  +      S++ G SF+               P+  
Sbjct: 112 PGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFD---------------PQRR 156

Query: 242 QHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRR 301
              A Q         P    P  ++  +E          + K++  ++R R  +  + RR
Sbjct: 157 AREAKQ---------PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRR 207

Query: 302 KSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREEN 361
           + K+ SK K+++SE++    +K+ H+S                 TP  ++ S D  R+ +
Sbjct: 208 ERKKSSKKKKHRSESES---KKRKHRSP----------------TPKSKRKSKDKKRKRS 248

Query: 362 NESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSK 421
             +  +          S D    +        S + +  T  LA R+      +  EG  
Sbjct: 249 RSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDA 308

Query: 422 PTKTPTTTPPETQQSPHLSLK 442
           P   P TT  +   SP  + K
Sbjct: 309 PFSEPGTTSTQRPSSPETATK 329



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 43/235 (18%), Positives = 84/235 (35%), Gaps = 31/235 (13%)

Query: 266 TKTKEDILESKSEQTKSK------QRDTQERKRE---------EKRKANRRKSKRMSKYK 310
           +K K+   ES+S++ K +      +R ++++KR+         + R+A+R  S   +   
Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS 272

Query: 311 ENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCE 370
           +      ++   K    +++       +   G    PF +  +  + R  + E+      
Sbjct: 273 DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPS 332

Query: 371 SSGSGDDSDDLYLPTCKYIQNPTSNSDRP---------------VTRPLAKRALKYTDEK 415
           S     D D       +   +P  +S  P                 +PLA   L      
Sbjct: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392

Query: 416 ETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPA 470
               + PT+   + P   ++ P  S  + +  S  P    R  S SP+  K +PA
Sbjct: 393 PPSEASPTR-DRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPA 446


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 25/136 (18%), Positives = 62/136 (45%), Gaps = 4/136 (2%)

Query: 272 ILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSS 331
           + E + ++ + ++R  QER+ +E+R+  RR+ +R    +E + E ++   ++++ +   +
Sbjct: 684 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 743

Query: 332 NDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSG---DDSDDLYLPTC-K 387
                  L+  +     +++    + R+   E E    E++G+    + + D+  P C  
Sbjct: 744 LRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTS 803

Query: 388 YIQNPTSNSDRPVTRP 403
           Y   P  +   P   P
Sbjct: 804 YQMTPQGHRAPPKINP 819


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 25/136 (18%), Positives = 62/136 (45%), Gaps = 4/136 (2%)

Query: 272 ILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSS 331
           + E + ++ + ++R  QER+ +E+R+  RR+ +R    +E + E ++   ++++ +   +
Sbjct: 680 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 739

Query: 332 NDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSG---DDSDDLYLPTC-K 387
                  L+  +     +++    + R+   E E    E++G+    + + D+  P C  
Sbjct: 740 LRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTS 799

Query: 388 YIQNPTSNSDRPVTRP 403
           Y   P  +   P   P
Sbjct: 800 YQMTPQGHRAPPKINP 815


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 4/83 (4%)

Query: 254 NLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQ---ERKREEKRKANRRKS-KRMSKY 309
           ++S    QPG  ++ +E   E ++ +   K+R+++   ER+  EKRK  R K  KR    
Sbjct: 24  HISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK 83

Query: 310 KENKSENKKTVPQKKMHKSVSSN 332
           KE K E KK   ++K  +    N
Sbjct: 84  KEKKGERKKEERERKKRRREKEN 106



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 17/50 (34%), Positives = 31/50 (62%)

Query: 269 KEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKK 318
           +E+  E + ++ K ++R+ +ERK+E +RK  R + K   K +E K E +K
Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 17/62 (27%), Positives = 36/62 (58%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           K +E   E K E+ K ++R  +ER++E +RK  +++ ++    KE + + K+   +KK  
Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190

Query: 327 KS 328
           ++
Sbjct: 191 RN 192



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 2/49 (4%)

Query: 276 KSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKK 324
           K E+ K K+R  +ERK+ E+ +  R+K +   + +E K E KK   +KK
Sbjct: 174 KEEERKEKER--KERKKRERNRKERKKERERKERRERKKERKKKEERKK 220



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 17/50 (34%), Positives = 29/50 (58%)

Query: 274 ESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQK 323
           E + ++ + K+R  +ER R+E++K   RK +R  K +  K E +K   QK
Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 268 TKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKE--NKSENKKTVPQKKM 325
           +KE     + E+ K ++R  +ERK+EE+ K   RK ++  + K+   K E +K   +K+ 
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186

Query: 326 HK 327
            K
Sbjct: 187 KK 188



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 17/61 (27%), Positives = 35/61 (57%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           K + +  + K E+ K ++R+  +++++ +RK   R+ K+  + KENK   +K   +KK  
Sbjct: 61  KERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK 120

Query: 327 K 327
           K
Sbjct: 121 K 121



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 8/69 (11%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERK--------REEKRKANRRKSKRMSKYKENKSENKK 318
           K +E   E + ++ + K+R  +ERK        R+EK +  R+K +R  K ++ + E K+
Sbjct: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204

Query: 319 TVPQKKMHK 327
              +KK  K
Sbjct: 205 RRERKKERK 213



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 11/61 (18%), Positives = 35/61 (57%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           K +E     + ++ + K+R+ +ERK+ E+++   ++ +R  K ++ + + ++   ++K  
Sbjct: 140 KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199

Query: 327 K 327
           +
Sbjct: 200 R 200



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 15/61 (24%), Positives = 31/61 (50%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           + KE+    K  + K  +   ++ KR++K K  R ++ +  K +E K E K+   +++  
Sbjct: 90  RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149

Query: 327 K 327
           K
Sbjct: 150 K 150



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 6/104 (5%)

Query: 267 KTKEDILESKSEQTKSKQR-----DTQERKREEKRKANRRKSKRMSKYKENKSENKKTVP 321
           + KE   + K ++ + K+R     + +ER+R+E+RK   RK +R  K +E + E ++   
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK-ERERKKEEREKERERKER 163

Query: 322 QKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESE 365
           +K+  K V   +      E        R +      RE     E
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 15/68 (22%), Positives = 38/68 (55%), Gaps = 1/68 (1%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANR-RKSKRMSKYKENKSENKKTVPQKKM 325
           + +++  + + +Q   K+ + +E++R+E++K  R RK ++  + ++ + E KK   +K+ 
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEE 217

Query: 326 HKSVSSND 333
            K     D
Sbjct: 218 RKKERQKD 225



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 10/69 (14%)

Query: 269 KEDILESKSEQTKSK---QRDTQERKREEKR-------KANRRKSKRMSKYKENKSENKK 318
           KE   E +SE+ K +   ++  +ER++E KR       K  R+K +R  K +  + ENK+
Sbjct: 49  KEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKE 108

Query: 319 TVPQKKMHK 327
              ++K  K
Sbjct: 109 GEEKEKRKK 117



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 21/104 (20%), Positives = 43/104 (41%), Gaps = 1/104 (0%)

Query: 278 EQTKSKQRDTQERKREEKRKAN-RRKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYN 336
           E+ + ++R  +E+K E K++   R+K +R  + KE + + K+   +KK     S      
Sbjct: 74  EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133

Query: 337 FNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDDSDD 380
              EE        ++   +   +E    E    E    G+  ++
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEE 177



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 17/59 (28%), Positives = 36/59 (61%), Gaps = 2/59 (3%)

Query: 267 KTKEDILESKSEQTKSKQRDTQ-ERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKK 324
           K + +  E K E+ + ++R+ + ERK++E+RK  R+K  R + ++E +   ++   +KK
Sbjct: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKD-RQTNWREKERGKRERKERKK 245



 Score = 29.3 bits (64), Expect = 9.3
 Identities = 15/64 (23%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 263 GTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANR--RKSKRMSKYKENKSENKKTV 320
           G   K + +  + + E+   +  + ++RK++EK++  R  ++ K   + +E K E +K  
Sbjct: 88  GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147

Query: 321 PQKK 324
            +KK
Sbjct: 148 ERKK 151


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 17/43 (39%), Positives = 26/43 (60%)

Query: 276 KSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKK 318
           K E+ K ++R+ +ERK+E +RK  R + K   K +  K E KK
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 18/64 (28%), Positives = 34/64 (53%)

Query: 274 ESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSND 333
           E K ++ K ++R+ +  +  ++RK  R + +R  + KE K E +K   +KK  K+    D
Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTD 216

Query: 334 AYNF 337
           +  F
Sbjct: 217 SQVF 220



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 17/58 (29%), Positives = 35/58 (60%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKK 324
           K KE   + K  + K +++  +E+K+ E+++  RR+ K+  + KE + ENK+   +K+
Sbjct: 78  KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 17/61 (27%), Positives = 35/61 (57%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           K +E     + E+ K K+R  +ER+ +++R+  R+K ++  + KE K E ++   ++K  
Sbjct: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161

Query: 327 K 327
           K
Sbjct: 162 K 162



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 2/61 (3%)

Query: 269 KEDILESKSEQTKSKQRDTQERK--REEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           KE     K E+ K ++R  +ER+  R+E+R+  RRK K+  K +E K   ++   +KK  
Sbjct: 61  KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120

Query: 327 K 327
           K
Sbjct: 121 K 121



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 269 KEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKS 328
           K +    K E+ + K++  +  K+ E+ +  R+K +   + +E K E KK   +KK  K 
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207

Query: 329 VSSND 333
               D
Sbjct: 208 DRKTD 212



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 16/54 (29%), Positives = 32/54 (59%)

Query: 274 ESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHK 327
           + + ++ + KQR  +ERK++++RK   R++K+  + K  K   KK   ++K  K
Sbjct: 98  KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 1/49 (2%)

Query: 276 KSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKK 324
           K ++ K ++R+ +  KRE KRK  R+K +R  K + N+ E KK   +K+
Sbjct: 140 KKKRRKERKREKERGKRERKRK-KRKKEEREKKRERNRKERKKERERKE 187



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 18/51 (35%), Positives = 30/51 (58%), Gaps = 2/51 (3%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENK 317
           K K++  E K E+ + +++  +ERK   +RK  R+K +R  K KE K + K
Sbjct: 162 KRKKEEREKKRERNRKERKKERERKERRERKKERKKERR--KKKERKKDRK 210



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 274 ESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSN 332
           E K  + ++KQR  +ERKR+++RK  RRK ++  K +  +   +K   +++  K    N
Sbjct: 119 ERKERERENKQR--RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 11/54 (20%), Positives = 35/54 (64%)

Query: 274 ESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHK 327
           E + ++ + ++++ ++RK+E+K++  +++ +R  K K+ + E ++   Q++  K
Sbjct: 81  EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 17/59 (28%), Positives = 34/59 (57%), Gaps = 1/59 (1%)

Query: 266 TKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKK 324
           T+ + +  + + E+ K K+   +ERKRE  +K  +++ KR  + KE + + K+   Q+K
Sbjct: 30  TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKR-ERGKERERKRKEREKQRK 87



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 15/59 (25%), Positives = 31/59 (52%)

Query: 269 KEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHK 327
           KE   + K  + + K+R  +ER++ +K K  R + +R  + ++ K E K+   + K  +
Sbjct: 73  KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRR 131



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 1/60 (1%)

Query: 269 KEDILESKSE-QTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHK 327
           KE   E+K   + K K+R  ++R++E KR+  R K +R  K ++ +   KK    +K  K
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180



 Score = 32.7 bits (73), Expect = 0.84
 Identities = 11/52 (21%), Positives = 30/52 (57%)

Query: 276 KSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHK 327
           + ++ + +++  +ER++E KR+  +++ K+  K +  K   +K   ++K  K
Sbjct: 36  RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 14/61 (22%), Positives = 34/61 (55%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           + +E   E K E+ K +++  ++R+R ++R+  R++ ++  K +  K   K+   +KK  
Sbjct: 46  RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRE 105

Query: 327 K 327
           +
Sbjct: 106 R 106



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 13/61 (21%), Positives = 32/61 (52%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           + KE     K ++ + K+R  +  K+E+K++  R + K   + ++ + + +K   +K+  
Sbjct: 36  RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95

Query: 327 K 327
           K
Sbjct: 96  K 96



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 23/94 (24%), Positives = 40/94 (42%), Gaps = 7/94 (7%)

Query: 276 KSEQTKSKQRDTQERKREEKRK------ANRRKSKRMSKYKENKSENKKTVPQKKMHKSV 329
           K E+ K K+R+ + ++RE KRK        RR+ +R  + KE K   +K   +++  K  
Sbjct: 60  KKEKKKRKKRE-RGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK 118

Query: 330 SSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNE 363
              +    N +        R+K      R+   E
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKE 152



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 13/61 (21%), Positives = 31/61 (50%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
           K + +    K ++ K K+   Q  +RE K+K  R++ +R +K +  +   K+   +++  
Sbjct: 87  KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146

Query: 327 K 327
           +
Sbjct: 147 R 147



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 12/52 (23%), Positives = 30/52 (57%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKK 318
           K +++      ++ + K++  +++KR ++RK  + + KR  K K+ K E ++
Sbjct: 118 KERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 12/52 (23%), Positives = 28/52 (53%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKK 318
           + KE     + ++ + +++  +ERK  E+    RR+ KR  + K+ + + +K
Sbjct: 97  RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 48/260 (18%), Positives = 99/260 (38%), Gaps = 21/260 (8%)

Query: 267  KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
            K++E +     ++   K+R   E K +   +   ++S      K  K +NK+    +++ 
Sbjct: 879  KSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKE--KDRELD 936

Query: 327  KSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDDSDDLYLPTC 386
            K   S D  + N+    H+   ++    D N+ + +E  +SL E +      + L  P  
Sbjct: 937  KKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQ-HEKPLSLKEKT----KDEPLKTPDG 991

Query: 387  KYIQNPTSNSDRPVTRPLAKRALKYTD----EKETEGSKPTKTPTTTPPETQQSPHLSLK 442
            K       + DR   R   K  ++       + E +  KP  +P +     ++   L   
Sbjct: 992  KEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEK-RLVND 1050

Query: 443  DITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKEPTLASKLRRGDPFTDL 502
            D+   S   ++ ++ L +     K    +   ++    + N  E  +  K +        
Sbjct: 1051 DLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKT------- 1103

Query: 503  CFLNSPIFKQKKDLRRSKKS 522
               ++P   + K+L RSK S
Sbjct: 1104 --KHTPTESKNKELTRSKSS 1121



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 23/99 (23%), Positives = 42/99 (42%)

Query: 267  KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
            K KE I + + E+ +++     + K +EK K    +SK     +   SE      ++K  
Sbjct: 1074 KHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQP 1133

Query: 327  KSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESE 365
            K   SN + + + +  + L        N  NR   +E+E
Sbjct: 1134 KDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENE 1172


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 48/260 (18%), Positives = 99/260 (38%), Gaps = 21/260 (8%)

Query: 267  KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
            K++E +     ++   K+R   E K +   +   ++S      K  K +NK+    +++ 
Sbjct: 902  KSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKE--KDRELD 959

Query: 327  KSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDDSDDLYLPTC 386
            K   S D  + N+    H+   ++    D N+ + +E  +SL E +      + L  P  
Sbjct: 960  KKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQ-HEKPLSLKEKT----KDEPLKTPDG 1014

Query: 387  KYIQNPTSNSDRPVTRPLAKRALKYTD----EKETEGSKPTKTPTTTPPETQQSPHLSLK 442
            K       + DR   R   K  ++       + E +  KP  +P +     ++   L   
Sbjct: 1015 KEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEK-RLVND 1073

Query: 443  DITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKEPTLASKLRRGDPFTDL 502
            D+   S   ++ ++ L +     K    +   ++    + N  E  +  K +        
Sbjct: 1074 DLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKT------- 1126

Query: 503  CFLNSPIFKQKKDLRRSKKS 522
               ++P   + K+L RSK S
Sbjct: 1127 --KHTPTESKNKELTRSKSS 1144



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 23/99 (23%), Positives = 42/99 (42%)

Query: 267  KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMH 326
            K KE I + + E+ +++     + K +EK K    +SK     +   SE      ++K  
Sbjct: 1097 KHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQP 1156

Query: 327  KSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESE 365
            K   SN + + + +  + L        N  NR   +E+E
Sbjct: 1157 KDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENE 1195


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 84/451 (18%), Positives = 181/451 (40%), Gaps = 48/451 (10%)

Query: 7   LKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDNNKMLVL 66
           L+++  D+  +I +     ++ +LAE   +   +    +++    +LL   ++  +M +L
Sbjct: 390 LQQALSDAENEIMRLSSLNQDNSLAEDNLK---LKMRIEVLEKEKSLLSQEKEELQMSLL 446

Query: 67  ALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSSGMDPNS 126
            L NE   +K      + L  E + L   L A + +L    + +     EI    +D  +
Sbjct: 447 KLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEI--EELDRQN 504

Query: 127 DDSSRNLF-VKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKSTDNVL 185
            ++++++  +KD  Q+  ++ E    G+S      I  + QD       + E K    + 
Sbjct: 505 QEATKHMILIKD--QLSKQQNE----GDSI-----ISKLKQDL------NDEKKRVHQLE 547

Query: 186 PRTVSVRSSLKKHCNSICQFD-SLDDFETSHLAGKSFEFERVGFLDPLVNMHIPENVQHN 244
              + +   L      + Q + +L+D    HL  +  E +    +D L         Q +
Sbjct: 548 DDKMDITKELDVQKEKLIQSEVALNDL---HLTKQKLEDKVENLVDQL------NKSQES 598

Query: 245 ACQWSKDQVNLSPKLIQ-PGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKS 303
                K+ + L   + Q     ++ + ++++S ++ + S  +DT  ++RE + +  ++  
Sbjct: 599 NVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNL 658

Query: 304 KRMSKYKENKSENKKTVPQKKM--HKSVSSNDAYNFNLEE---GVHLTPFRQKVSNDSNR 358
             + +  EN    KK     KM   K V + +     LEE   G +     +    ++ +
Sbjct: 659 SELEQLNENL---KKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLK 715

Query: 359 EENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETE 418
            E  E E  LC +     +  + Y  T + + N   N +    +   +  +K   +K+ E
Sbjct: 716 MEKGEIEAELCWAKKRLLEEANKYEKTIEELSN-ARNLNTSALQLEHEHLIKLNQKKDME 774

Query: 419 GSKPTKTPTTTPPETQQSPHLSLKDITNVSL 449
            ++  K       E   + H   KD+ + SL
Sbjct: 775 IAELKKN-----IEQMDTDHKETKDVLSSSL 800


>gi|21361684 G patch domain containing 1 [Homo sapiens]
          Length = 931

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 6/97 (6%)

Query: 251 DQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYK 310
           ++    P+L  P  F       LE   ++   K +D  + K+E +RK  ++K  R  K+K
Sbjct: 826 EREEFGPRL--PPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHK 883

Query: 311 ENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTP 347
             K +NKK    +K   S SS+ + + + EE   ++P
Sbjct: 884 -GKQKNKK---PEKSSSSESSDSSDSQSDEETADVSP 916


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 46/205 (22%), Positives = 79/205 (38%), Gaps = 20/205 (9%)

Query: 293 EEKRKANRRK--SKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQ 350
           E K++   +K  SK +++++E  +EN K   +K   K +S N++ +   E        ++
Sbjct: 43  EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRER-------KK 95

Query: 351 KVSNDSNREENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALK 410
           K    S R  ++ S     +SS S  DS+D      K  +   + S         K +  
Sbjct: 96  KRKKKSCRSSSSSSS---SDSSSSSSDSEDEEKKQGKRRKKKKNRS--------YKSSQS 144

Query: 411 YTDEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPA 470
            T E E+E  +  K    +  ET++   +          YP  K      S + +     
Sbjct: 145 STHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204

Query: 471 VALPKRRCTASVNYKEPTLASKLRR 495
            A  KRRC      KE     K ++
Sbjct: 205 QAKKKRRCEEREQAKEKVKKKKKKQ 229



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 27/108 (25%), Positives = 54/108 (50%), Gaps = 8/108 (7%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYK-------ENKSENKKT 319
           + K+    S S  +      + + + EEK++  RRK K+   YK       E++SE+K++
Sbjct: 97  RKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKES 156

Query: 320 VPQKKMHKSVSSNDAYNFNLEEGVHLT-PFRQKVSNDSNREENNESEV 366
           V +KK  K  +  +    +L +    + P  + +S++S+ E + E +V
Sbjct: 157 VKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 26/117 (22%), Positives = 50/117 (42%), Gaps = 4/117 (3%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSEN-KKTVPQKKM 325
           KT    L    E+     +   E+ RE+    N   SK+  + K+ K ++ + +      
Sbjct: 52  KTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSS 111

Query: 326 HKSVSSNDAYNFNLEEGVHLTPFRQ---KVSNDSNREENNESEVSLCESSGSGDDSD 379
             S SS+D+ +   ++G      +    K S  S  E  +ES+ S+ +   S D+++
Sbjct: 112 DSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETE 168



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 25/118 (21%), Positives = 52/118 (44%), Gaps = 9/118 (7%)

Query: 269 KEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKS-------ENKKTVP 321
           K+++ +S+ +     +  +++R+R++KRK    +S   S   ++ S       E KK   
Sbjct: 70  KKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGK 129

Query: 322 --QKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDD 377
             +KK ++S  S+ +     E     +  ++K S D   +E +   +S        DD
Sbjct: 130 RRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDD 187



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 250 KDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKY 309
           KD  +LS K  +  ++   K    ES SE    +    ++++R E+R+  + K K+  K 
Sbjct: 171 KDVRSLSKK--RKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK 228

Query: 310 KENKSENKKTVPQKKMHKS 328
           +  K   KK       HKS
Sbjct: 229 QHKKHSKKKKKKSGSSHKS 247


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 47/208 (22%), Positives = 79/208 (37%), Gaps = 20/208 (9%)

Query: 270 EDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQK-KMHKS 328
           +D+ +  SEQ K+K  D  E+K +   K  R+K K+    K+     K    QK K  K 
Sbjct: 305 KDVQQESSEQ-KNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQ 363

Query: 329 VSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSG-DDSDDLYLPTCK 387
               +  +  L          +K SN +   E  + + SL +S   G  D     + T  
Sbjct: 364 AKEKEVESLKLPS--------EKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSD 415

Query: 388 YIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPPETQ---------QSPH 438
                    +  VT    +     +D++E      TKT T+   E +           P+
Sbjct: 416 LSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPY 475

Query: 439 LSLKDITNVSLYPVVKIRRLSLSPKKNK 466
           L  K  ++      V+ RR S++ +K +
Sbjct: 476 LYSKYYSDSDDELTVEQRRQSIAKEKEE 503



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 59/273 (21%), Positives = 106/273 (38%), Gaps = 22/273 (8%)

Query: 268 TKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHK 327
           T +D  ++K  +TK++  D+ E K +  R A   K    SKY  + S+++ TV Q++   
Sbjct: 439 TSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSD-SDDELTVEQRRQSI 497

Query: 328 SVSSNDAY---NFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDDSDDL--- 381
           +    +       N E+       + + +  S  +    S V L ESS    +       
Sbjct: 498 AKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIK 557

Query: 382 -YLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPPETQQSPHLS 440
             L   K ++   + S +   R    R ++   +K+ +  + +K    T    ++    S
Sbjct: 558 EVLKERKVLEKKVALSKK---RKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISS 614

Query: 441 LKDITNV--SLYPVVKIRRLSLS----PKKNKASPAVALPKRRCTASV---NYKEPTLAS 491
            K++ +V     P    RRLS S     +    S      KRR +  V     +E T   
Sbjct: 615 SKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTR 674

Query: 492 KLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMK 524
            ++R    +++C       KQK  L+  K   K
Sbjct: 675 DVKRQVERSEIC--TEEPQKQKSTLKNEKHLKK 705



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 29/175 (16%), Positives = 68/175 (38%), Gaps = 16/175 (9%)

Query: 250 KDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKY 309
           KD  N+     +   + +  ++ L++     K K   ++E K    +    + ++R+S+ 
Sbjct: 578 KDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSES 637

Query: 310 KENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLC 369
                ENK     ++ HK  +S       ++E       +++V       E  + + S  
Sbjct: 638 LHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTL 697

Query: 370 ESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTK 424
           ++               K+++    +S+ P  + L K+ +K + EK      P++
Sbjct: 698 KNE--------------KHLKK--DDSETPHLKSLLKKEVKSSKEKPEREKTPSE 736



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 61/297 (20%), Positives = 104/297 (35%), Gaps = 57/297 (19%)

Query: 270  EDILESKSEQTKSKQRDTQERK----REEKRKANRRKSKRMSKY---------KENKSEN 316
            E+ ++ +S+QTK    D  ERK     E K     +  K +S+Y         KEN  + 
Sbjct: 769  EENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKE 828

Query: 317  KKTVPQKKM--HKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGS 374
            ++   +K    HKS  S+D+                K+  DS   + +   +     S S
Sbjct: 829  RRLSAEKTKAEHKSRRSSDS----------------KIQKDSLGSKQHGITLQRRSESYS 872

Query: 375  GDDSD-DLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSK-----------P 422
             D  D D              + ++  T+ L +  L    + +T+G +            
Sbjct: 873  EDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGA 932

Query: 423  TKTPTTTPP-----------ETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAV 471
            TK  TT  P           E Q+   +  K      + PV++    S    +  +S   
Sbjct: 933  TKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRA 992

Query: 472  ALP--KRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKSMKQI 526
             LP  K +  +  +     L  KL  G     L   +  I K+K + +   K  K++
Sbjct: 993  KLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDI-KKKDENKSDDKDGKEV 1048


>gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]
          Length = 322

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 38/167 (22%), Positives = 71/167 (42%), Gaps = 24/167 (14%)

Query: 207 SLDDFETSHLAGKSFEFERVGFLDPLVNMHIPENVQHNACQWSKDQVNLSPKLIQPGTFT 266
           ++D+F    + G++   + V       N   P++        S++  +++ +L + G   
Sbjct: 93  AVDNFNGIKIKGRTIRVDHVS------NYRAPKD--------SEEIDDVTRQLQEKGCGA 138

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKR--MSKYKENKSENKKTVPQK- 323
           +T    L   SE  K  ++  +++K ++K+K  + K+ R   ++   + S  +KTV +K 
Sbjct: 139 RTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKD 198

Query: 324 ----KMHKSVSSNDAYNFNLEEGVHLTPFRQKVS---NDSNREENNE 363
               K H S +S  A      EG  L   R   S    D  RE   E
Sbjct: 199 DTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKE 245


>gi|118766347 zinc finger CCCH-type domain containing 6 [Homo
           sapiens]
          Length = 1189

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 2/66 (3%)

Query: 288 QERKREEKRKANR--RKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHL 345
           +E K  EK+K+ +  RKS++  K +  K ++K+   +K  H S SS+D+ +++L+  V  
Sbjct: 32  KEAKENEKQKSEKAYRKSRKKHKKEREKKKSKRRKREKHKHNSPSSDDSSDYSLDSDVEH 91

Query: 346 TPFRQK 351
           T    K
Sbjct: 92  TESSHK 97


>gi|17978469 cyclin T2 isoform b [Homo sapiens]
          Length = 730

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 60/329 (18%), Positives = 121/329 (36%), Gaps = 24/329 (7%)

Query: 97  YALKGKLTSQQTVEPAQNQEICSSGMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQ 156
           Y L       Q  + A+ +++ S   + +   S  N+  +  P I L  + L  + +   
Sbjct: 343 YGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLH-SGLHHRPDKIS 401

Query: 157 IEDQIPTIPQDTLGVDFDSGEAKSTDNVLPRTVSVRSSLKKHCNSICQFDSLDDF----- 211
               +        G     G   +T  ++P+ +S+    +K        D  D +     
Sbjct: 402 DHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQV 461

Query: 212 ETSHLAGKSFEFERVGFLDPLVNMHIP-ENVQHNACQWSKDQVNLSPKLIQPGTFTKTKE 270
           E  H  G+S          P + M IP  N +       +   +L  ++  P T     +
Sbjct: 462 EQQHKQGQSQAASSSSVTSP-IKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASK 520

Query: 271 DILESKSEQTKSKQRDTQERKREEKRKANRRKSK-RMSKYKENKSENKKTVPQKKMHKSV 329
           + L+ K + + S++  + +    + + ++   S+    K+KE+ S    T   K  H   
Sbjct: 521 EELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHS 580

Query: 330 SSNDAYNFNLEEGVHLTPFRQKV---------SNDSNREENNESEVS------LCESSGS 374
            S+   + +  +G+  T  R  V         S+ S+R+  + ++ S      + +SS S
Sbjct: 581 GSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKS 640

Query: 375 GDDSDDLYLPTCKYIQNPTSNSDRPVTRP 403
              S        +YI +  S  + P+  P
Sbjct: 641 SGSSSSSSSSVKQYISSHNSVFNHPLPPP 669


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 42/177 (23%), Positives = 76/177 (42%), Gaps = 23/177 (12%)

Query: 266 TKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKE--------NKSENK 317
           TK K        E+++S+ R  + R R   R  +R +SK   +Y+E        ++S  +
Sbjct: 552 TKGKHSYNSRTRERSRSRDRSRRVRSRTHDR--DRSRSKEYHRYREQEYRRRGRSRSRER 609

Query: 318 KTVPQKKMHKS--VSSNDAYNFNLEEGV--HLTPFRQKVSNDSNREENNESEVSLCESSG 373
           +T P +   K       D+ +   EE    +   +R + S  S+R+EN+ESE  +   S 
Sbjct: 610 RTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSR 669

Query: 374 SGDDSDDLYLPTCKYIQNP-----TSNSDRPVTRPLAK----RALKYTDEKETEGSK 421
             + S++         Q+P      S+ D  +   + K      ++ + EKE + SK
Sbjct: 670 DHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSK 726



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 3/62 (4%)

Query: 261 QPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTV 320
           Q  + +   E   E KS++ K K R    + ++EK+K  R+KSK+ S   E+++EN +  
Sbjct: 211 QSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKK--RKKSKK-SASSESEAENLEAQ 267

Query: 321 PQ 322
           PQ
Sbjct: 268 PQ 269



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSK--RMSKYKENKSENKKTVPQKK 324
           + K        E++KSK+RD++  + EEKR  +R K +     K KE +S++K    ++ 
Sbjct: 455 RAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERS 514

Query: 325 MHKSVS 330
             K  S
Sbjct: 515 RSKEKS 520



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 15/136 (11%)

Query: 275 SKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDA 334
           S+S+  + ++RD++  +REE +  N+ K +       ++ EN ++  +K+M+     +++
Sbjct: 616 SRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES--EKRMYSKSRDHNS 673

Query: 335 YNFNLEEGV--HLTPFRQ-KVSNDSN----------REENNESEVSLCESSGSGDDSDDL 381
            N + E+      +PF + K S+  N           +E   S V        G ++D +
Sbjct: 674 SNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHV 733

Query: 382 YLPTCKYIQNPTSNSD 397
           +    K+    +  +D
Sbjct: 734 HEKNKKFDHESSPGTD 749



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 274 ESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSND 333
           +S S+   S      E   EEK K      KR  K+++N  ++KK   ++K  K  +S++
Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSK------KRKKKHRKNSRKHKKEKKKRKKSKKSASSE 258

Query: 334 AYNFNLE 340
           +   NLE
Sbjct: 259 SEAENLE 265



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 30/182 (16%), Positives = 77/182 (42%), Gaps = 5/182 (2%)

Query: 243 HNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRK 302
           H     S ++ N   K ++       + DI  +  +  K K +  ++R + + R  ++ K
Sbjct: 409 HRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNK-VKKRAKSKSRSKSKEK 467

Query: 303 SK---RMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNRE 359
           SK   R SK+  N+ +  ++  + + H++V   +  + +  +    +  ++K     ++ 
Sbjct: 468 SKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKS 527

Query: 360 ENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEG 419
             ++   S  +   +   S +  +   K+  N +   +R  +R  ++R    T +++   
Sbjct: 528 NEHDHSKSKEKDRRAQSRSRECDITKGKHSYN-SRTRERSRSRDRSRRVRSRTHDRDRSR 586

Query: 420 SK 421
           SK
Sbjct: 587 SK 588



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 28/141 (19%), Positives = 60/141 (42%), Gaps = 9/141 (6%)

Query: 267 KTKEDILESKSEQTKSKQRDTQERKREEKRKAN-RRKSKRMSKYKENKSEN--------K 317
           + KE  +      ++S  R  ++ K+ +  K+N + +  R +  K++K +N        K
Sbjct: 400 RVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSK 459

Query: 318 KTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDD 377
                K+  KS   +  +N N E+ +      +   N   +E+ ++S+    E S S + 
Sbjct: 460 SRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK 519

Query: 378 SDDLYLPTCKYIQNPTSNSDR 398
           S  L   + ++  + +   DR
Sbjct: 520 SKQLESKSNEHDHSKSKEKDR 540


>gi|148839362 LSM14 homolog B [Homo sapiens]
          Length = 385

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 8/135 (5%)

Query: 255 LSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKS 314
           L+ +  QP +  KT  D+++  + Q + +  D  E +R ++R++  R+++  S+ +   +
Sbjct: 185 LNGRQAQPSS--KTASDVVQPAAVQAQGQVND--ENRRPQRRRSGNRRTRNRSRGQNRPT 240

Query: 315 ENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVS-NDSNREENNESEVSLCESSG 373
             K+   + +      S +A  FN EE      F++K++  D   E+  E ++++   S 
Sbjct: 241 NVKENTIKFEGDFDFESANA-QFNREELDK--EFKKKLNFKDDKAEKGEEKDLAVVTQSA 297

Query: 374 SGDDSDDLYLPTCKY 388
                +DL  P C Y
Sbjct: 298 EAPAEEDLLGPNCYY 312


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,635,767
Number of Sequences: 37866
Number of extensions: 1001374
Number of successful extensions: 8554
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 379
Number of HSP's that attempted gapping in prelim test: 5982
Number of HSP's gapped (non-prelim): 2369
length of query: 527
length of database: 18,247,518
effective HSP length: 107
effective length of query: 420
effective length of database: 14,195,856
effective search space: 5962259520
effective search space used: 5962259520
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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