Guide to the Human Genome
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Search of human proteins with 5902064

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5902064 rabphilin 3A-like (without C2 domains) [Homo
sapiens]
         (315 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5902064 rabphilin 3A-like (without C2 domains) [Homo sapiens]      655   0.0  
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             216   2e-56
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            213   1e-55
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                       69   5e-12
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                       69   5e-12
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a...    68   1e-11
gi|110227631 synaptotagmin-like 3 [Homo sapiens]                       63   4e-10
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi...    56   5e-08
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]             53   3e-07
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]             53   3e-07
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]              53   3e-07
gi|59853352 myosin VIIA and Rab interacting protein [Homo sapiens]     52   5e-07
gi|55750053 atrophin-1 [Homo sapiens]                                  41   0.001
gi|55750041 atrophin-1 [Homo sapiens]                                  41   0.001
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    40   0.003
gi|109826351 melanophilin isoform 2 [Homo sapiens]                     40   0.004
gi|13129108 melanophilin isoform 1 [Homo sapiens]                      40   0.004
gi|51173722 bromodomain and PHD finger-containing protein 1 isof...    39   0.005
gi|51173720 bromodomain and PHD finger-containing protein 1 isof...    39   0.005
gi|239748099 PREDICTED: hypothetical protein [Homo sapiens]            39   0.006
gi|91208420 bassoon protein [Homo sapiens]                             39   0.006
gi|33286446 opioid growth factor receptor [Homo sapiens]               37   0.023
gi|153281158 dual specificity phosphatase 8 [Homo sapiens]             37   0.023
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    36   0.039
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    36   0.039
gi|89051034 PREDICTED: methyl-CpG-binding domain protein 3-like ...    36   0.039
gi|113428063 PREDICTED: similar to methyl-CpG binding domain pro...    36   0.039
gi|38683860 insulin receptor substrate 2 [Homo sapiens]                36   0.039
gi|157389003 methyl-CpG binding domain protein 3-like 2 [Homo sa...    36   0.039
gi|169217724 PREDICTED: similar to methyl-CpG binding domain pro...    36   0.051

>gi|5902064 rabphilin 3A-like (without C2 domains) [Homo sapiens]
          Length = 315

 Score =  655 bits (1690), Expect = 0.0
 Identities = 315/315 (100%), Positives = 315/315 (100%)

Query: 1   MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQ 60
           MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQ
Sbjct: 1   MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQ 60

Query: 61  RAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVC 120
           RAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVC
Sbjct: 61  RAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVC 120

Query: 121 TKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPL 180
           TKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPL
Sbjct: 121 TKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPL 180

Query: 181 PTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWK 240
           PTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWK
Sbjct: 181 PTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWK 240

Query: 241 ESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRA 300
           ESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRA
Sbjct: 241 ESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRA 300

Query: 301 PAADAAPAGPSSCLG 315
           PAADAAPAGPSSCLG
Sbjct: 301 PAADAAPAGPSSCLG 315


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  216 bits (550), Expect = 2e-56
 Identities = 131/336 (38%), Positives = 184/336 (54%), Gaps = 40/336 (11%)

Query: 1   MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTY-QTEKQRRKQHLSPAEVEAILQVI 59
           M DT+F + +++W+ P+DR L  ++KLQ GWSVH   Q ++QR+++ L+  E E I +VI
Sbjct: 1   MTDTVFSNSSNRWMYPSDRPL--QSKLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVI 58

Query: 60  QRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKV 119
            RAE+++ +EQ+RIGRLV+RLE MR+NV G+G+++C+LCGE LG LGS+ V C+DC+K V
Sbjct: 59  ARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNV 118

Query: 120 CTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRP 179
           CTKCG+E +  +   +WLCKIC EQREVWKRSGAWF+KG PK +LP   P +   P  +P
Sbjct: 119 CTKCGVETN-NRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQ-QP 176

Query: 180 LPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTG-------VR- 231
           +    A  +P           ARG     DS+        +  D   + G       VR 
Sbjct: 177 VSEPAAPEQPAPEPKHPARAPARG-----DSEDRRGPGQKTGPDPASAPGRGNYGPPVRR 231

Query: 232 --------DRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGP 283
                     +  + W  SGG+ ++ R      P  L    S  AS     GS   P  P
Sbjct: 232 ASEARMSSSSRDSESWDHSGGAGDSSR-----SPAGLRRANSVQAS-RPAPGSVQSPAPP 285

Query: 284 RPGLTRRAPVKDTPGRAPAA-------DAAPAGPSS 312
           +PG     P    PG  PA        + AP+ P +
Sbjct: 286 QPG-QPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGT 320


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  213 bits (543), Expect = 1e-55
 Identities = 131/338 (38%), Positives = 182/338 (53%), Gaps = 40/338 (11%)

Query: 1   MADTIFGSGNDQWVCPNDRQLALRAK--LQTGWSVHTY-QTEKQRRKQHLSPAEVEAILQ 57
           M DT+F + +++W+ P+DR L    K  LQ GWSVH   Q ++QR+++ L+  E E I +
Sbjct: 1   MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR 60

Query: 58  VIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRK 117
           VI RAE+++ +EQ+RIGRLV+RLE MR+NV G+G+++C+LCGE LG LGS+ V C+DC+K
Sbjct: 61  VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK 120

Query: 118 KVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHF 177
            VCTKCG+E +  +   +WLCKIC EQREVWKRSGAWF+KG PK +LP   P +   P  
Sbjct: 121 NVCTKCGVETN-NRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQ- 178

Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTG-------V 230
           +P+    A  +P           ARG     DS+        +  D   + G       V
Sbjct: 179 QPVSEPAAPEQPAPEPKHPARAPARG-----DSEDRRGPGQKTGPDPASAPGRGNYGPPV 233

Query: 231 R---------DRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPG 281
           R           +  + W  SGG+ ++ R      P  L    S  AS     GS   P 
Sbjct: 234 RRASEARMSSSSRDSESWDHSGGAGDSSR-----SPAGLRRANSVQAS-RPAPGSVQSPA 287

Query: 282 GPRPGLTRRAPVKDTPGRAPAA-------DAAPAGPSS 312
            P+PG     P    PG  PA        + AP+ P +
Sbjct: 288 PPQPG-QPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGT 324


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 40/115 (34%), Positives = 57/115 (49%), Gaps = 9/115 (7%)

Query: 47  LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQ-----CLLCGEV 101
           LS  E + IL V+QR E +   +++RI RL   L  ++R     G        C  C E 
Sbjct: 10  LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69

Query: 102 LGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFY 156
           LG L   +  C+ C   VC  C I+ S G     W CK+C+++ E+ K +G WFY
Sbjct: 70  LGRLSPKTNTCRGCNHLVCRDCRIQESNGT----WRCKVCAKEIELKKATGDWFY 120


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 40/115 (34%), Positives = 57/115 (49%), Gaps = 9/115 (7%)

Query: 47  LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQ-----CLLCGEV 101
           LS  E + IL V+QR E +   +++RI RL   L  ++R     G        C  C E 
Sbjct: 10  LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69

Query: 102 LGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFY 156
           LG L   +  C+ C   VC  C I+ S G     W CK+C+++ E+ K +G WFY
Sbjct: 70  LGRLSPKTNTCRGCNHLVCRDCRIQESNGT----WRCKVCAKEIELKKATGDWFY 120


>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
           [Homo sapiens]
          Length = 1349

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 46/165 (27%), Positives = 75/165 (45%), Gaps = 21/165 (12%)

Query: 46  HLSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNV--MGNGLSQ--------- 94
           HL+  E + IL V+ R ++ +  EQ  + +L ++ E  +  V  MG    Q         
Sbjct: 31  HLTEEERKIILAVMDRQKKEEEKEQSVLKKLHQQFEMYKEQVKKMGEESQQQQEQKGDAP 90

Query: 95  -CLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGA 153
            C +C +   F       C  C+ K C +CG   S    + +W+C +C +Q+E+  +SGA
Sbjct: 91  TCGICHKTK-FADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCRKQQEILTKSGA 149

Query: 154 WFYKGLPKYILPLKTPGRADDPHFRPLPTE--PAEREPRSSETSR 196
           WFY           TP + D    R L  E  P E++P+  E ++
Sbjct: 150 WFYNS------GSNTPQQPDQKVLRGLRNEEAPQEKKPKLHEQTQ 188


>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
          Length = 542

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 8/116 (6%)

Query: 47  LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQ-----CLLCGEV 101
           L   E EAILQV+ R + +   E++R  +L   L+ +R     N   +     C  C +V
Sbjct: 10  LKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCARCQQV 69

Query: 102 LGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYK 157
           LGFL      C+ C  +VC +C +     +    W C +C E R V  ++G WFY+
Sbjct: 70  LGFLLHRGAVCRGCSHRVCAQCRVFL---RGTHAWKCTVCFEDRNVKIKTGEWFYE 122


>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo
           sapiens]
          Length = 1692

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 22/155 (14%)

Query: 95  CLLCGEVLGFLGSSSVFCKDCRKKVCTKCG----IEASPGQKRPLWLCKICSEQREVWKR 150
           C +C +   F       C  CR K C +CG    + ++   K  +W+C +C +Q+E+  +
Sbjct: 116 CGICHKTK-FADGCGHLCSYCRTKFCARCGGRVSLRSNNEDKVVMWVCNLCRKQQEILTK 174

Query: 151 SGAWFYKGLPKYILPLKTPGRADDPHFRPLPTEPAEREPRSSETSRIYTWARGRVVSSDS 210
           SGAWF+   P+        G   D         P E++ R  E SR             S
Sbjct: 175 SGAWFFGSGPQ---QTSQDGTLSDTATGAGSEVPREKKARLQERSR-------------S 218

Query: 211 DSDSDLSSSSLEDRLPSTGVRDR-KGDKPWKESGG 244
            +    +++S +D  P +   DR KG +P +++ G
Sbjct: 219 QTPLSTAAASSQDAAPPSAPPDRSKGAEPSQQALG 253


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 8/149 (5%)

Query: 51  EVEAILQVIQRAERLDVLEQQRIGRLV-ERLETMRRN--VMGNGLSQCLLCGEVLGFLGS 107
           E E IL V++R E L  +E +RI +L  E LE  RR+          C+ C   LG +  
Sbjct: 17  EKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLGLIFD 76

Query: 108 SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLK 167
               C+ C  +VC +C +    G     W C +C +  ++   +G WF++   K    + 
Sbjct: 77  RGDPCQACSLRVCRECRVAGPNGS----WKCTVCDKIAQLRIITGEWFFEEKAKRFKQVN 132

Query: 168 TPGRADDPHFRPLPTEPAEREPRSSETSR 196
             G  D      L   P   E +S E +R
Sbjct: 133 VLG-TDVVRQSILRRSPGAEEVQSQEQTR 160


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 8/149 (5%)

Query: 51  EVEAILQVIQRAERLDVLEQQRIGRLV-ERLETMRRN--VMGNGLSQCLLCGEVLGFLGS 107
           E E IL V++R E L  +E +RI +L  E LE  RR+          C+ C   LG +  
Sbjct: 17  EKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLGLIFD 76

Query: 108 SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLK 167
               C+ C  +VC +C +    G     W C +C +  ++   +G WF++   K    + 
Sbjct: 77  RGDPCQACSLRVCRECRVAGPNGS----WKCTVCDKIAQLRIITGEWFFEEKAKRFKQVN 132

Query: 168 TPGRADDPHFRPLPTEPAEREPRSSETSR 196
             G  D      L   P   E +S E +R
Sbjct: 133 VLG-TDVVRQSILRRSPGAEEVQSQEQTR 160


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 8/149 (5%)

Query: 51  EVEAILQVIQRAERLDVLEQQRIGRLV-ERLETMRRN--VMGNGLSQCLLCGEVLGFLGS 107
           E E IL V++R E L  +E +RI +L  E LE  RR+          C+ C   LG +  
Sbjct: 17  EKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLGLIFD 76

Query: 108 SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLK 167
               C+ C  +VC +C +    G     W C +C +  ++   +G WF++   K    + 
Sbjct: 77  RGDPCQACSLRVCRECRVAGPNGS----WKCTVCDKIAQLRIITGEWFFEEKAKRFKQVN 132

Query: 168 TPGRADDPHFRPLPTEPAEREPRSSETSR 196
             G  D      L   P   E +S E +R
Sbjct: 133 VLG-TDVVRQSILRRSPGAEEVQSQEQTR 160


>gi|59853352 myosin VIIA and Rab interacting protein [Homo sapiens]
          Length = 859

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 9/119 (7%)

Query: 47  LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERL--ETMRRNVMGNGLS----QCLLCGE 100
           L+  E E +LQV+QR   L   E++R+  L ++L  E  + +++          C+ C  
Sbjct: 10  LTDDETEHVLQVVQRDFNLRKKEEERLSELKQKLDEEGSKCSILSKHQQFVEHCCMRCCS 69

Query: 101 VLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGL 159
              FL ++   C DC+  VC  C    S  +    W+C +C + R +  +S  WFY  +
Sbjct: 70  PFTFLVNTKRQCGDCKFNVCKSC---CSYQKHEKAWVCCVCQQARLLRAQSLEWFYNNV 125


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 40/135 (29%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDK 237
           RP P  PA   P  S+ S       G  VSS S+S S  S  S     PS     +    
Sbjct: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY 599

Query: 238 PWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTP 297
           P+         P    T     LS   +++AS   G  +A PPG P  G  +RAP     
Sbjct: 600 PF--------PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG--KRAPSPGAY 649

Query: 298 GRAPAADAAPAGPSS 312
             A      P  P S
Sbjct: 650 KTATPPGYKPGSPPS 664



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 255 HP---PGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPS 311
           HP   PG   G  S    G  G G+A   GGP  G  ++ P   TP    ++ A+ A P+
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGG--KQHPPPTTPISVSSSGASGAPPT 273


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 40/135 (29%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDK 237
           RP P  PA   P  S+ S       G  VSS S+S S  S  S     PS     +    
Sbjct: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY 599

Query: 238 PWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTP 297
           P+         P    T     LS   +++AS   G  +A PPG P  G  +RAP     
Sbjct: 600 PF--------PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG--KRAPSPGAY 649

Query: 298 GRAPAADAAPAGPSS 312
             A      P  P S
Sbjct: 650 KTATPPGYKPGSPPS 664



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 255 HP---PGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPS 311
           HP   PG   G  S    G  G G+A   GGP  G  ++ P   TP    ++ A+ A P+
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGG--KQHPPPTTPISVSSSGASGAPPT 273


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 40/110 (36%), Positives = 45/110 (40%), Gaps = 20/110 (18%)

Query: 207 SSDSDSDSDLSSSSL-EDRLPS---TGVRDRKGDKPWKESGGSVEAPRMGFTHPPGHLSG 262
           SSDSDSDSD S +SL ED  P     G R  +G    KE+ G   A R G   P      
Sbjct: 327 SSDSDSDSDSSGTSLSEDEAPGEARNGRRPARGSSGEKENRGGRRAVRPGSGGP------ 380

Query: 263 CQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSS 312
               L S   G     P   PRP    R  V+  P R+P  D  P    S
Sbjct: 381 ----LLSWPLG-----PAPPPRPPQLERHVVRPPP-RSPEPDTLPLAAGS 420


>gi|109826351 melanophilin isoform 2 [Homo sapiens]
          Length = 572

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 9/117 (7%)

Query: 47  LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERL--ETMRRNVMGNGL----SQCLLCGE 100
           L+  E + +L+V+QR   L   E++R+  L  ++  E+ +R ++ +      + C  C +
Sbjct: 10  LTDEEAQHVLEVVQRDFDLRRKEEERLEALKGKIKKESSKRELLSDTAHLNETHCARCLQ 69

Query: 101 VLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYK 157
               L +S   C +C    C  CG    P ++   W+C  C   R V   S  W+Y+
Sbjct: 70  PYQLLVNSKRQCLECGLFTCKSCG-RVHPEEQG--WICDPCHLARVVKIGSLEWYYE 123


>gi|13129108 melanophilin isoform 1 [Homo sapiens]
          Length = 600

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 9/117 (7%)

Query: 47  LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERL--ETMRRNVMGNGL----SQCLLCGE 100
           L+  E + +L+V+QR   L   E++R+  L  ++  E+ +R ++ +      + C  C +
Sbjct: 10  LTDEEAQHVLEVVQRDFDLRRKEEERLEALKGKIKKESSKRELLSDTAHLNETHCARCLQ 69

Query: 101 VLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYK 157
               L +S   C +C    C  CG    P ++   W+C  C   R V   S  W+Y+
Sbjct: 70  PYQLLVNSKRQCLECGLFTCKSCG-RVHPEEQG--WICDPCHLARVVKIGSLEWYYE 123


>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2
            [Homo sapiens]
          Length = 1214

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 71/257 (27%), Positives = 94/257 (36%), Gaps = 37/257 (14%)

Query: 51   EVEAILQVIQRAERLDVLEQQRIG---RLVERLETMRRNVMGNGLSQCLLCGEVLGFLGS 107
            EV A  Q + R+ R  +++++      +L  + ET R     +G S            GS
Sbjct: 795  EVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPSS----------RGS 844

Query: 108  SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQ--REVWKRSGAWFYKGLPKYILP 165
             +     C K   T    E S  Q+    L    S     EV +R+   F K  PK   P
Sbjct: 845  LTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGP 904

Query: 166  LKTPGRADD-------PHFRPLPTEPAEREPRSSETSRIYTWARGRVV--SSDSDSDSDL 216
             K PGR          P     P  P +    SS   R     RGR    SS SDSDSD 
Sbjct: 905  PKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQR----KRGRSPRPSSSSDSDSDK 960

Query: 217  SSSSLEDRLPSTGVRDRKGDKPWKES----GGSVEAPRMGFTHPPGHLSGCQSSLASGET 272
            S+      LP+ G     G++P K+S          PR          S   SS AS  T
Sbjct: 961  STEDPPMDLPANGFSG--GNQPVKKSFLVYRNDCSLPRSSSDSESS--SSSSSSAASDRT 1016

Query: 273  GTGSADPPGGPRPGLTR 289
             T +    G  +P  +R
Sbjct: 1017 ST-TPSKQGRGKPSFSR 1032


>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1
            [Homo sapiens]
          Length = 1220

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 71/257 (27%), Positives = 94/257 (36%), Gaps = 37/257 (14%)

Query: 51   EVEAILQVIQRAERLDVLEQQRIG---RLVERLETMRRNVMGNGLSQCLLCGEVLGFLGS 107
            EV A  Q + R+ R  +++++      +L  + ET R     +G S            GS
Sbjct: 801  EVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPSS----------RGS 850

Query: 108  SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQ--REVWKRSGAWFYKGLPKYILP 165
             +     C K   T    E S  Q+    L    S     EV +R+   F K  PK   P
Sbjct: 851  LTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGP 910

Query: 166  LKTPGRADD-------PHFRPLPTEPAEREPRSSETSRIYTWARGRVV--SSDSDSDSDL 216
             K PGR          P     P  P +    SS   R     RGR    SS SDSDSD 
Sbjct: 911  PKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQR----KRGRSPRPSSSSDSDSDK 966

Query: 217  SSSSLEDRLPSTGVRDRKGDKPWKES----GGSVEAPRMGFTHPPGHLSGCQSSLASGET 272
            S+      LP+ G     G++P K+S          PR          S   SS AS  T
Sbjct: 967  STEDPPMDLPANGFSG--GNQPVKKSFLVYRNDCSLPRSSSDSESS--SSSSSSAASDRT 1022

Query: 273  GTGSADPPGGPRPGLTR 289
             T +    G  +P  +R
Sbjct: 1023 ST-TPSKQGRGKPSFSR 1038


>gi|239748099 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 38/129 (29%), Positives = 53/129 (41%), Gaps = 16/129 (12%)

Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDK 237
           RPL  EP  RE       +   W R R   S + +   +S++       + G+R ++   
Sbjct: 135 RPLAGEPW-REAARRRPQQCPQWGRARESRSAALASPRVSNAPTTPASRNPGLRAQERQS 193

Query: 238 PWKESGGS---VEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVK 294
             + +GG     E PR+    P G   G +S  A+G           GPR   TRR P  
Sbjct: 194 GRRAAGGGGARAEPPRVPPCRPAGCSGGNRSRRAAG----------AGPRT--TRRKPPP 241

Query: 295 DTPGRAPAA 303
             PG APAA
Sbjct: 242 RPPGTAPAA 250


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 58/217 (26%), Positives = 83/217 (38%), Gaps = 27/217 (12%)

Query: 112 CKDCRKKVCTKCGIEASPGQKR-PLWLCKICSEQREV-WKRSGAWFYKGLPKYILPLKTP 169
           C  C  KVC +CG   +P   +   WLC  C  QR +    + A   K   +   P  +P
Sbjct: 190 CTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSP 249

Query: 170 GRADDPHFRPL--PTEPAEREP-------RSSETSRIYTWARGRVVSSDSDSDSDLSSSS 220
             A  P  +PL  P +   R P       R +ET+R  T   G   ++       +S   
Sbjct: 250 --AHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARA-TSVPGPAQAAAPPEVGRVSPQP 306

Query: 221 LEDRLPSTG-VRDRKGDKPWKESG------GSVEAPRMGFTHPPGHLSGCQSSLASGETG 273
            +   PST   R   G+ P K +       G+ E  + G T   G L G  +SL +  + 
Sbjct: 307 PQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLT---GKLFGLGASLLTQAST 363

Query: 274 TGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGP 310
             S  P    +    + AP K TP       +  AGP
Sbjct: 364 LMSVQPEADTQ---GQPAPSKGTPKIVFNDASKEAGP 397



 Score = 32.0 bits (71), Expect = 0.73
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 6/56 (10%)

Query: 95  CLLCGEVLGFLGSSSVF----CKDCRKKVCTKCGIEASPG-QKRPLWLCKICSEQR 145
           C LC   L  +GS S      C  CR +VC  CG   +P   ++  WLC  C  +R
Sbjct: 465 CPLCQAELN-VGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKR 519



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 34/140 (24%), Positives = 54/140 (38%), Gaps = 27/140 (19%)

Query: 169  PGRADDPHFRPLPTEPAEREPRSSETSR---------IYTWARGRVVSSDSDSDSDLSSS 219
            P ++  P  R +P+  A R+P++ +  +           T AR +  S  +   S  ++S
Sbjct: 3756 PQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAAS 3815

Query: 220  SLEDRL---PSTGVRDRKGDKPWKE----SGGSVEAPRMGFTHPPGHLSGCQSSLASGET 272
                +    PST    +    P  E    S G+ +AP+ G           ++  A    
Sbjct: 3816 QPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQG-----------RAPQAQPAP 3864

Query: 273  GTGSADPPGGPRPGLTRRAP 292
            G G A    G RPG T  AP
Sbjct: 3865 GPGPAGVKAGARPGGTPGAP 3884


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 38/151 (25%), Positives = 59/151 (39%), Gaps = 13/151 (8%)

Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDS---DLSSSSLEDRLPSTGVRDRK 234
           RP P  P E + R  E SR           S S+ +    +L   +L      TG ++  
Sbjct: 373 RPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVG 432

Query: 235 GD------KPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGT----GSADPPGGPR 284
           G       +P ++  G+  A ++         +G  +++ASG   T    GS  P G P+
Sbjct: 433 GQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 492

Query: 285 PGLTRRAPVKDTPGRAPAADAAPAGPSSCLG 315
            G +     +DT GR    +  P  PS   G
Sbjct: 493 AGHSENGVEEDTEGRTGPKEGTPGSPSETPG 523



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 40/152 (26%), Positives = 50/152 (32%), Gaps = 26/152 (17%)

Query: 169 PGRADDPHFRPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPST 228
           PG A  P  +PL    A++              R R    +   DS   +S     L   
Sbjct: 436 PGEAVQPCRQPLGARVADK-------------VRKRRKVDEGAGDSAAVASGGAQTLALA 482

Query: 229 GVRDRKGDKPWKESGGSVEAPRMGFTHP----PGHLSGCQSSLASGETGTGSADPPG--- 281
           G     G      S   VE    G T P    PG  S       +G  G   A+ P    
Sbjct: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542

Query: 282 GPRPGLTRRAPVKDTPGRAPAADAA--PAGPS 311
           GPRP      P  D P  +P+      PAGP+
Sbjct: 543 GPRPA----GPAGDEPAESPSETPGPRPAGPA 570


>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
          Length = 625

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 6/114 (5%)

Query: 189 PRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEA 248
           P    TS +    RG  +SSD   D++    S    + S     R+ D P     G  EA
Sbjct: 362 PTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPG--EA 419

Query: 249 PRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPA 302
           P++     P   SG    L+S    +  A P   PRP    R P   +P R+PA
Sbjct: 420 PKLCKLDSP---SGAALGLSSPSPDSPDAAPEARPRPRRRPRPPA-GSPARSPA 469


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 10/109 (9%)

Query: 207 SSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEAPRMGFTHPPGH-----LS 261
           SS S S S  SSSS      S+  + +K D P   + G+   P      P        LS
Sbjct: 94  SSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLS 153

Query: 262 GCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGP 310
           G Q    + + G  ++ P  G  PGL   A     PG  PA    P GP
Sbjct: 154 GHQHLFGNLKRGGPASGP--GVTPGLGAPA---GAPGPLPAPSQTPPGP 197


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 10/109 (9%)

Query: 207 SSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEAPRMGFTHPPGH-----LS 261
           SS S S S  SSSS      S+  + +K D P   + G+   P      P        LS
Sbjct: 94  SSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLS 153

Query: 262 GCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGP 310
           G Q    + + G  ++ P  G  PGL   A     PG  PA    P GP
Sbjct: 154 GHQHLFGNLKRGGPASGP--GVTPGLGAPA---GAPGPLPAPSQTPPGP 197


>gi|89051034 PREDICTED: methyl-CpG-binding domain protein 3-like
           3-like [Homo sapiens]
          Length = 208

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 14/97 (14%)

Query: 226 PSTGVRDRKGDKPWKESGGSVEAPRMGFTHP---------PGHLSGCQSSLASGETGTGS 276
           P   VR RKGD+  ++        R+    P         P HL    S LA G  G  S
Sbjct: 68  PDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGE-S 126

Query: 277 ADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSC 313
            D  G  R     R+P++ TPGR PA    P     C
Sbjct: 127 LDRAGAERV----RSPLEPTPGRFPAVAGGPTPGMGC 159


>gi|113428063 PREDICTED: similar to methyl-CpG binding domain
           protein 3-like 2 [Homo sapiens]
          Length = 204

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 14/97 (14%)

Query: 226 PSTGVRDRKGDKPWKESGGSVEAPRMGFTHP---------PGHLSGCQSSLASGETGTGS 276
           P   VR RKGD+  ++        R+    P         P HL    S LA G  G  S
Sbjct: 68  PDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGE-S 126

Query: 277 ADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSC 313
            D  G  R     R+P++ TPGR PA    P     C
Sbjct: 127 LDRAGAERV----RSPLEPTPGRFPAVAGGPTPGMGC 159


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 5/73 (6%)

Query: 242 SGGSVEAPR---MGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPG 298
           +GG+++  R   M   H P   +   S  +S   G+GS  PP GP P L    P+   PG
Sbjct: 421 AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPH--PLHHGPG 478

Query: 299 RAPAADAAPAGPS 311
           + P++ +A A  S
Sbjct: 479 QRPSSGSASASGS 491


>gi|157389003 methyl-CpG binding domain protein 3-like 2 [Homo
           sapiens]
          Length = 208

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 14/97 (14%)

Query: 226 PSTGVRDRKGDKPWKESGGSVEAPRMGFTHP---------PGHLSGCQSSLASGETGTGS 276
           P   VR RKGD+  ++        R+    P         P HL    S LA G  G  S
Sbjct: 68  PDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGE-S 126

Query: 277 ADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSC 313
            D  G  R     R+P++ TPGR PA    P     C
Sbjct: 127 LDRAGAERV----RSPLEPTPGRFPAVAGGPTPGMGC 159


>gi|169217724 PREDICTED: similar to methyl-CpG binding domain
           protein 3-like 2, partial [Homo sapiens]
          Length = 193

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 14/97 (14%)

Query: 226 PSTGVRDRKGD----KP-----WKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGS 276
           P   VR RKGD    KP     +++          G    P HL    S LA G T + S
Sbjct: 53  PDNQVRRRKGDEHLEKPQQLCAYRKLQALQPCSSQGEGSSPLHLESVLSILAPG-TASES 111

Query: 277 ADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSC 313
            D  G  R     R+P++ TPGR PA    P     C
Sbjct: 112 LDRAGAERV----RSPLEPTPGRFPAVAGGPTPGMGC 144


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,596,041
Number of Sequences: 37866
Number of extensions: 903589
Number of successful extensions: 5257
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 241
Number of HSP's that attempted gapping in prelim test: 4936
Number of HSP's gapped (non-prelim): 564
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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