BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5902064 rabphilin 3A-like (without C2 domains) [Homo sapiens] (315 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5902064 rabphilin 3A-like (without C2 domains) [Homo sapiens] 655 0.0 gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 216 2e-56 gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 213 1e-55 gi|193804862 synaptotagmin-like 4 [Homo sapiens] 69 5e-12 gi|193804860 synaptotagmin-like 4 [Homo sapiens] 69 5e-12 gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 68 1e-11 gi|110227631 synaptotagmin-like 3 [Homo sapiens] 63 4e-10 gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi... 56 5e-08 gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 53 3e-07 gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 53 3e-07 gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] 53 3e-07 gi|59853352 myosin VIIA and Rab interacting protein [Homo sapiens] 52 5e-07 gi|55750053 atrophin-1 [Homo sapiens] 41 0.001 gi|55750041 atrophin-1 [Homo sapiens] 41 0.001 gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 40 0.003 gi|109826351 melanophilin isoform 2 [Homo sapiens] 40 0.004 gi|13129108 melanophilin isoform 1 [Homo sapiens] 40 0.004 gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 39 0.005 gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 39 0.005 gi|239748099 PREDICTED: hypothetical protein [Homo sapiens] 39 0.006 gi|91208420 bassoon protein [Homo sapiens] 39 0.006 gi|33286446 opioid growth factor receptor [Homo sapiens] 37 0.023 gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 37 0.023 gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo... 36 0.039 gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo... 36 0.039 gi|89051034 PREDICTED: methyl-CpG-binding domain protein 3-like ... 36 0.039 gi|113428063 PREDICTED: similar to methyl-CpG binding domain pro... 36 0.039 gi|38683860 insulin receptor substrate 2 [Homo sapiens] 36 0.039 gi|157389003 methyl-CpG binding domain protein 3-like 2 [Homo sa... 36 0.039 gi|169217724 PREDICTED: similar to methyl-CpG binding domain pro... 36 0.051 >gi|5902064 rabphilin 3A-like (without C2 domains) [Homo sapiens] Length = 315 Score = 655 bits (1690), Expect = 0.0 Identities = 315/315 (100%), Positives = 315/315 (100%) Query: 1 MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQ 60 MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQ Sbjct: 1 MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQ 60 Query: 61 RAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVC 120 RAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVC Sbjct: 61 RAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVC 120 Query: 121 TKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPL 180 TKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPL Sbjct: 121 TKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPL 180 Query: 181 PTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWK 240 PTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWK Sbjct: 181 PTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWK 240 Query: 241 ESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRA 300 ESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRA Sbjct: 241 ESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRA 300 Query: 301 PAADAAPAGPSSCLG 315 PAADAAPAGPSSCLG Sbjct: 301 PAADAAPAGPSSCLG 315 >gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] Length = 690 Score = 216 bits (550), Expect = 2e-56 Identities = 131/336 (38%), Positives = 184/336 (54%), Gaps = 40/336 (11%) Query: 1 MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTY-QTEKQRRKQHLSPAEVEAILQVI 59 M DT+F + +++W+ P+DR L ++KLQ GWSVH Q ++QR+++ L+ E E I +VI Sbjct: 1 MTDTVFSNSSNRWMYPSDRPL--QSKLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVI 58 Query: 60 QRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKV 119 RAE+++ +EQ+RIGRLV+RLE MR+NV G+G+++C+LCGE LG LGS+ V C+DC+K V Sbjct: 59 ARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNV 118 Query: 120 CTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRP 179 CTKCG+E + + +WLCKIC EQREVWKRSGAWF+KG PK +LP P + P +P Sbjct: 119 CTKCGVETN-NRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQ-QP 176 Query: 180 LPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTG-------VR- 231 + A +P ARG DS+ + D + G VR Sbjct: 177 VSEPAAPEQPAPEPKHPARAPARG-----DSEDRRGPGQKTGPDPASAPGRGNYGPPVRR 231 Query: 232 --------DRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGP 283 + + W SGG+ ++ R P L S AS GS P P Sbjct: 232 ASEARMSSSSRDSESWDHSGGAGDSSR-----SPAGLRRANSVQAS-RPAPGSVQSPAPP 285 Query: 284 RPGLTRRAPVKDTPGRAPAA-------DAAPAGPSS 312 +PG P PG PA + AP+ P + Sbjct: 286 QPG-QPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGT 320 >gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] Length = 694 Score = 213 bits (543), Expect = 1e-55 Identities = 131/338 (38%), Positives = 182/338 (53%), Gaps = 40/338 (11%) Query: 1 MADTIFGSGNDQWVCPNDRQLALRAK--LQTGWSVHTY-QTEKQRRKQHLSPAEVEAILQ 57 M DT+F + +++W+ P+DR L K LQ GWSVH Q ++QR+++ L+ E E I + Sbjct: 1 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR 60 Query: 58 VIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRK 117 VI RAE+++ +EQ+RIGRLV+RLE MR+NV G+G+++C+LCGE LG LGS+ V C+DC+K Sbjct: 61 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK 120 Query: 118 KVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHF 177 VCTKCG+E + + +WLCKIC EQREVWKRSGAWF+KG PK +LP P + P Sbjct: 121 NVCTKCGVETN-NRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQ- 178 Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTG-------V 230 +P+ A +P ARG DS+ + D + G V Sbjct: 179 QPVSEPAAPEQPAPEPKHPARAPARG-----DSEDRRGPGQKTGPDPASAPGRGNYGPPV 233 Query: 231 R---------DRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPG 281 R + + W SGG+ ++ R P L S AS GS P Sbjct: 234 RRASEARMSSSSRDSESWDHSGGAGDSSR-----SPAGLRRANSVQAS-RPAPGSVQSPA 287 Query: 282 GPRPGLTRRAPVKDTPGRAPAA-------DAAPAGPSS 312 P+PG P PG PA + AP+ P + Sbjct: 288 PPQPG-QPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGT 324 >gi|193804862 synaptotagmin-like 4 [Homo sapiens] Length = 671 Score = 68.9 bits (167), Expect = 5e-12 Identities = 40/115 (34%), Positives = 57/115 (49%), Gaps = 9/115 (7%) Query: 47 LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQ-----CLLCGEV 101 LS E + IL V+QR E + +++RI RL L ++R G C C E Sbjct: 10 LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69 Query: 102 LGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFY 156 LG L + C+ C VC C I+ S G W CK+C+++ E+ K +G WFY Sbjct: 70 LGRLSPKTNTCRGCNHLVCRDCRIQESNGT----WRCKVCAKEIELKKATGDWFY 120 >gi|193804860 synaptotagmin-like 4 [Homo sapiens] Length = 671 Score = 68.9 bits (167), Expect = 5e-12 Identities = 40/115 (34%), Positives = 57/115 (49%), Gaps = 9/115 (7%) Query: 47 LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQ-----CLLCGEV 101 LS E + IL V+QR E + +++RI RL L ++R G C C E Sbjct: 10 LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69 Query: 102 LGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFY 156 LG L + C+ C VC C I+ S G W CK+C+++ E+ K +G WFY Sbjct: 70 LGRLSPKTNTCRGCNHLVCRDCRIQESNGT----WRCKVCAKEIELKKATGDWFY 120 >gi|154354983 regulating synaptic membrane exocytosis 2 isoform a [Homo sapiens] Length = 1349 Score = 67.8 bits (164), Expect = 1e-11 Identities = 46/165 (27%), Positives = 75/165 (45%), Gaps = 21/165 (12%) Query: 46 HLSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNV--MGNGLSQ--------- 94 HL+ E + IL V+ R ++ + EQ + +L ++ E + V MG Q Sbjct: 31 HLTEEERKIILAVMDRQKKEEEKEQSVLKKLHQQFEMYKEQVKKMGEESQQQQEQKGDAP 90 Query: 95 -CLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGA 153 C +C + F C C+ K C +CG S + +W+C +C +Q+E+ +SGA Sbjct: 91 TCGICHKTK-FADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCRKQQEILTKSGA 149 Query: 154 WFYKGLPKYILPLKTPGRADDPHFRPLPTE--PAEREPRSSETSR 196 WFY TP + D R L E P E++P+ E ++ Sbjct: 150 WFYNS------GSNTPQQPDQKVLRGLRNEEAPQEKKPKLHEQTQ 188 >gi|110227631 synaptotagmin-like 3 [Homo sapiens] Length = 542 Score = 62.8 bits (151), Expect = 4e-10 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 8/116 (6%) Query: 47 LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQ-----CLLCGEV 101 L E EAILQV+ R + + E++R +L L+ +R N + C C +V Sbjct: 10 LKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCARCQQV 69 Query: 102 LGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYK 157 LGFL C+ C +VC +C + + W C +C E R V ++G WFY+ Sbjct: 70 LGFLLHRGAVCRGCSHRVCAQCRVFL---RGTHAWKCTVCFEDRNVKIKTGEWFYE 122 >gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapiens] Length = 1692 Score = 55.8 bits (133), Expect = 5e-08 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 22/155 (14%) Query: 95 CLLCGEVLGFLGSSSVFCKDCRKKVCTKCG----IEASPGQKRPLWLCKICSEQREVWKR 150 C +C + F C CR K C +CG + ++ K +W+C +C +Q+E+ + Sbjct: 116 CGICHKTK-FADGCGHLCSYCRTKFCARCGGRVSLRSNNEDKVVMWVCNLCRKQQEILTK 174 Query: 151 SGAWFYKGLPKYILPLKTPGRADDPHFRPLPTEPAEREPRSSETSRIYTWARGRVVSSDS 210 SGAWF+ P+ G D P E++ R E SR S Sbjct: 175 SGAWFFGSGPQ---QTSQDGTLSDTATGAGSEVPREKKARLQERSR-------------S 218 Query: 211 DSDSDLSSSSLEDRLPSTGVRDR-KGDKPWKESGG 244 + +++S +D P + DR KG +P +++ G Sbjct: 219 QTPLSTAAASSQDAAPPSAPPDRSKGAEPSQQALG 253 >gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] Length = 730 Score = 53.1 bits (126), Expect = 3e-07 Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 8/149 (5%) Query: 51 EVEAILQVIQRAERLDVLEQQRIGRLV-ERLETMRRN--VMGNGLSQCLLCGEVLGFLGS 107 E E IL V++R E L +E +RI +L E LE RR+ C+ C LG + Sbjct: 17 EKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLGLIFD 76 Query: 108 SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLK 167 C+ C +VC +C + G W C +C + ++ +G WF++ K + Sbjct: 77 RGDPCQACSLRVCRECRVAGPNGS----WKCTVCDKIAQLRIITGEWFFEEKAKRFKQVN 132 Query: 168 TPGRADDPHFRPLPTEPAEREPRSSETSR 196 G D L P E +S E +R Sbjct: 133 VLG-TDVVRQSILRRSPGAEEVQSQEQTR 160 >gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] Length = 752 Score = 53.1 bits (126), Expect = 3e-07 Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 8/149 (5%) Query: 51 EVEAILQVIQRAERLDVLEQQRIGRLV-ERLETMRRN--VMGNGLSQCLLCGEVLGFLGS 107 E E IL V++R E L +E +RI +L E LE RR+ C+ C LG + Sbjct: 17 EKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLGLIFD 76 Query: 108 SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLK 167 C+ C +VC +C + G W C +C + ++ +G WF++ K + Sbjct: 77 RGDPCQACSLRVCRECRVAGPNGS----WKCTVCDKIAQLRIITGEWFFEEKAKRFKQVN 132 Query: 168 TPGRADDPHFRPLPTEPAEREPRSSETSR 196 G D L P E +S E +R Sbjct: 133 VLG-TDVVRQSILRRSPGAEEVQSQEQTR 160 >gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] Length = 730 Score = 53.1 bits (126), Expect = 3e-07 Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 8/149 (5%) Query: 51 EVEAILQVIQRAERLDVLEQQRIGRLV-ERLETMRRN--VMGNGLSQCLLCGEVLGFLGS 107 E E IL V++R E L +E +RI +L E LE RR+ C+ C LG + Sbjct: 17 EKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLGLIFD 76 Query: 108 SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLK 167 C+ C +VC +C + G W C +C + ++ +G WF++ K + Sbjct: 77 RGDPCQACSLRVCRECRVAGPNGS----WKCTVCDKIAQLRIITGEWFFEEKAKRFKQVN 132 Query: 168 TPGRADDPHFRPLPTEPAEREPRSSETSR 196 G D L P E +S E +R Sbjct: 133 VLG-TDVVRQSILRRSPGAEEVQSQEQTR 160 >gi|59853352 myosin VIIA and Rab interacting protein [Homo sapiens] Length = 859 Score = 52.4 bits (124), Expect = 5e-07 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 9/119 (7%) Query: 47 LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERL--ETMRRNVMGNGLS----QCLLCGE 100 L+ E E +LQV+QR L E++R+ L ++L E + +++ C+ C Sbjct: 10 LTDDETEHVLQVVQRDFNLRKKEEERLSELKQKLDEEGSKCSILSKHQQFVEHCCMRCCS 69 Query: 101 VLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGL 159 FL ++ C DC+ VC C S + W+C +C + R + +S WFY + Sbjct: 70 PFTFLVNTKRQCGDCKFNVCKSC---CSYQKHEKAWVCCVCQQARLLRAQSLEWFYNNV 125 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 41.2 bits (95), Expect = 0.001 Identities = 40/135 (29%), Positives = 49/135 (36%), Gaps = 10/135 (7%) Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDK 237 RP P PA P S+ S G VSS S+S S S S PS + Sbjct: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY 599 Query: 238 PWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTP 297 P+ P T LS +++AS G +A PPG P G +RAP Sbjct: 600 PF--------PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG--KRAPSPGAY 649 Query: 298 GRAPAADAAPAGPSS 312 A P P S Sbjct: 650 KTATPPGYKPGSPPS 664 Score = 28.9 bits (63), Expect = 6.2 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 255 HP---PGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPS 311 HP PG G S G G G+A GGP G ++ P TP ++ A+ A P+ Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGG--KQHPPPTTPISVSSSGASGAPPT 273 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 41.2 bits (95), Expect = 0.001 Identities = 40/135 (29%), Positives = 49/135 (36%), Gaps = 10/135 (7%) Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDK 237 RP P PA P S+ S G VSS S+S S S S PS + Sbjct: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY 599 Query: 238 PWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTP 297 P+ P T LS +++AS G +A PPG P G +RAP Sbjct: 600 PF--------PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG--KRAPSPGAY 649 Query: 298 GRAPAADAAPAGPSS 312 A P P S Sbjct: 650 KTATPPGYKPGSPPS 664 Score = 28.9 bits (63), Expect = 6.2 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 255 HP---PGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPS 311 HP PG G S G G G+A GGP G ++ P TP ++ A+ A P+ Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGG--KQHPPPTTPISVSSSGASGAPPT 273 >gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapiens] Length = 694 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/110 (36%), Positives = 45/110 (40%), Gaps = 20/110 (18%) Query: 207 SSDSDSDSDLSSSSL-EDRLPS---TGVRDRKGDKPWKESGGSVEAPRMGFTHPPGHLSG 262 SSDSDSDSD S +SL ED P G R +G KE+ G A R G P Sbjct: 327 SSDSDSDSDSSGTSLSEDEAPGEARNGRRPARGSSGEKENRGGRRAVRPGSGGP------ 380 Query: 263 CQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSS 312 L S G P PRP R V+ P R+P D P S Sbjct: 381 ----LLSWPLG-----PAPPPRPPQLERHVVRPPP-RSPEPDTLPLAAGS 420 >gi|109826351 melanophilin isoform 2 [Homo sapiens] Length = 572 Score = 39.7 bits (91), Expect = 0.004 Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 9/117 (7%) Query: 47 LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERL--ETMRRNVMGNGL----SQCLLCGE 100 L+ E + +L+V+QR L E++R+ L ++ E+ +R ++ + + C C + Sbjct: 10 LTDEEAQHVLEVVQRDFDLRRKEEERLEALKGKIKKESSKRELLSDTAHLNETHCARCLQ 69 Query: 101 VLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYK 157 L +S C +C C CG P ++ W+C C R V S W+Y+ Sbjct: 70 PYQLLVNSKRQCLECGLFTCKSCG-RVHPEEQG--WICDPCHLARVVKIGSLEWYYE 123 >gi|13129108 melanophilin isoform 1 [Homo sapiens] Length = 600 Score = 39.7 bits (91), Expect = 0.004 Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 9/117 (7%) Query: 47 LSPAEVEAILQVIQRAERLDVLEQQRIGRLVERL--ETMRRNVMGNGL----SQCLLCGE 100 L+ E + +L+V+QR L E++R+ L ++ E+ +R ++ + + C C + Sbjct: 10 LTDEEAQHVLEVVQRDFDLRRKEEERLEALKGKIKKESSKRELLSDTAHLNETHCARCLQ 69 Query: 101 VLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYK 157 L +S C +C C CG P ++ W+C C R V S W+Y+ Sbjct: 70 PYQLLVNSKRQCLECGLFTCKSCG-RVHPEEQG--WICDPCHLARVVKIGSLEWYYE 123 >gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2 [Homo sapiens] Length = 1214 Score = 39.3 bits (90), Expect = 0.005 Identities = 71/257 (27%), Positives = 94/257 (36%), Gaps = 37/257 (14%) Query: 51 EVEAILQVIQRAERLDVLEQQRIG---RLVERLETMRRNVMGNGLSQCLLCGEVLGFLGS 107 EV A Q + R+ R +++++ +L + ET R +G S GS Sbjct: 795 EVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPSS----------RGS 844 Query: 108 SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQ--REVWKRSGAWFYKGLPKYILP 165 + C K T E S Q+ L S EV +R+ F K PK P Sbjct: 845 LTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGP 904 Query: 166 LKTPGRADD-------PHFRPLPTEPAEREPRSSETSRIYTWARGRVV--SSDSDSDSDL 216 K PGR P P P + SS R RGR SS SDSDSD Sbjct: 905 PKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQR----KRGRSPRPSSSSDSDSDK 960 Query: 217 SSSSLEDRLPSTGVRDRKGDKPWKES----GGSVEAPRMGFTHPPGHLSGCQSSLASGET 272 S+ LP+ G G++P K+S PR S SS AS T Sbjct: 961 STEDPPMDLPANGFSG--GNQPVKKSFLVYRNDCSLPRSSSDSESS--SSSSSSAASDRT 1016 Query: 273 GTGSADPPGGPRPGLTR 289 T + G +P +R Sbjct: 1017 ST-TPSKQGRGKPSFSR 1032 >gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1 [Homo sapiens] Length = 1220 Score = 39.3 bits (90), Expect = 0.005 Identities = 71/257 (27%), Positives = 94/257 (36%), Gaps = 37/257 (14%) Query: 51 EVEAILQVIQRAERLDVLEQQRIG---RLVERLETMRRNVMGNGLSQCLLCGEVLGFLGS 107 EV A Q + R+ R +++++ +L + ET R +G S GS Sbjct: 801 EVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPSS----------RGS 850 Query: 108 SSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQ--REVWKRSGAWFYKGLPKYILP 165 + C K T E S Q+ L S EV +R+ F K PK P Sbjct: 851 LTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGP 910 Query: 166 LKTPGRADD-------PHFRPLPTEPAEREPRSSETSRIYTWARGRVV--SSDSDSDSDL 216 K PGR P P P + SS R RGR SS SDSDSD Sbjct: 911 PKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQR----KRGRSPRPSSSSDSDSDK 966 Query: 217 SSSSLEDRLPSTGVRDRKGDKPWKES----GGSVEAPRMGFTHPPGHLSGCQSSLASGET 272 S+ LP+ G G++P K+S PR S SS AS T Sbjct: 967 STEDPPMDLPANGFSG--GNQPVKKSFLVYRNDCSLPRSSSDSESS--SSSSSSAASDRT 1022 Query: 273 GTGSADPPGGPRPGLTR 289 T + G +P +R Sbjct: 1023 ST-TPSKQGRGKPSFSR 1038 >gi|239748099 PREDICTED: hypothetical protein [Homo sapiens] Length = 295 Score = 38.9 bits (89), Expect = 0.006 Identities = 38/129 (29%), Positives = 53/129 (41%), Gaps = 16/129 (12%) Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDK 237 RPL EP RE + W R R S + + +S++ + G+R ++ Sbjct: 135 RPLAGEPW-REAARRRPQQCPQWGRARESRSAALASPRVSNAPTTPASRNPGLRAQERQS 193 Query: 238 PWKESGGS---VEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVK 294 + +GG E PR+ P G G +S A+G GPR TRR P Sbjct: 194 GRRAAGGGGARAEPPRVPPCRPAGCSGGNRSRRAAG----------AGPRT--TRRKPPP 241 Query: 295 DTPGRAPAA 303 PG APAA Sbjct: 242 RPPGTAPAA 250 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 38.9 bits (89), Expect = 0.006 Identities = 58/217 (26%), Positives = 83/217 (38%), Gaps = 27/217 (12%) Query: 112 CKDCRKKVCTKCGIEASPGQKR-PLWLCKICSEQREV-WKRSGAWFYKGLPKYILPLKTP 169 C C KVC +CG +P + WLC C QR + + A K + P +P Sbjct: 190 CTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSP 249 Query: 170 GRADDPHFRPL--PTEPAEREP-------RSSETSRIYTWARGRVVSSDSDSDSDLSSSS 220 A P +PL P + R P R +ET+R T G ++ +S Sbjct: 250 --AHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARA-TSVPGPAQAAAPPEVGRVSPQP 306 Query: 221 LEDRLPSTG-VRDRKGDKPWKESG------GSVEAPRMGFTHPPGHLSGCQSSLASGETG 273 + PST R G+ P K + G+ E + G T G L G +SL + + Sbjct: 307 PQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLT---GKLFGLGASLLTQAST 363 Query: 274 TGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGP 310 S P + + AP K TP + AGP Sbjct: 364 LMSVQPEADTQ---GQPAPSKGTPKIVFNDASKEAGP 397 Score = 32.0 bits (71), Expect = 0.73 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 6/56 (10%) Query: 95 CLLCGEVLGFLGSSSVF----CKDCRKKVCTKCGIEASPG-QKRPLWLCKICSEQR 145 C LC L +GS S C CR +VC CG +P ++ WLC C +R Sbjct: 465 CPLCQAELN-VGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKR 519 Score = 28.9 bits (63), Expect = 6.2 Identities = 34/140 (24%), Positives = 54/140 (38%), Gaps = 27/140 (19%) Query: 169 PGRADDPHFRPLPTEPAEREPRSSETSR---------IYTWARGRVVSSDSDSDSDLSSS 219 P ++ P R +P+ A R+P++ + + T AR + S + S ++S Sbjct: 3756 PQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAAS 3815 Query: 220 SLEDRL---PSTGVRDRKGDKPWKE----SGGSVEAPRMGFTHPPGHLSGCQSSLASGET 272 + PST + P E S G+ +AP+ G ++ A Sbjct: 3816 QPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQG-----------RAPQAQPAP 3864 Query: 273 GTGSADPPGGPRPGLTRRAP 292 G G A G RPG T AP Sbjct: 3865 GPGPAGVKAGARPGGTPGAP 3884 >gi|33286446 opioid growth factor receptor [Homo sapiens] Length = 677 Score = 37.0 bits (84), Expect = 0.023 Identities = 38/151 (25%), Positives = 59/151 (39%), Gaps = 13/151 (8%) Query: 178 RPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDS---DLSSSSLEDRLPSTGVRDRK 234 RP P P E + R E SR S S+ + +L +L TG ++ Sbjct: 373 RPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVG 432 Query: 235 GD------KPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGT----GSADPPGGPR 284 G +P ++ G+ A ++ +G +++ASG T GS P G P+ Sbjct: 433 GQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 492 Query: 285 PGLTRRAPVKDTPGRAPAADAAPAGPSSCLG 315 G + +DT GR + P PS G Sbjct: 493 AGHSENGVEEDTEGRTGPKEGTPGSPSETPG 523 Score = 31.2 bits (69), Expect = 1.3 Identities = 40/152 (26%), Positives = 50/152 (32%), Gaps = 26/152 (17%) Query: 169 PGRADDPHFRPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPST 228 PG A P +PL A++ R R + DS +S L Sbjct: 436 PGEAVQPCRQPLGARVADK-------------VRKRRKVDEGAGDSAAVASGGAQTLALA 482 Query: 229 GVRDRKGDKPWKESGGSVEAPRMGFTHP----PGHLSGCQSSLASGETGTGSADPPG--- 281 G G S VE G T P PG S +G G A+ P Sbjct: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542 Query: 282 GPRPGLTRRAPVKDTPGRAPAADAA--PAGPS 311 GPRP P D P +P+ PAGP+ Sbjct: 543 GPRPA----GPAGDEPAESPSETPGPRPAGPA 570 >gi|153281158 dual specificity phosphatase 8 [Homo sapiens] Length = 625 Score = 37.0 bits (84), Expect = 0.023 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 6/114 (5%) Query: 189 PRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEA 248 P TS + RG +SSD D++ S + S R+ D P G EA Sbjct: 362 PTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPG--EA 419 Query: 249 PRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPA 302 P++ P SG L+S + A P PRP R P +P R+PA Sbjct: 420 PKLCKLDSP---SGAALGLSSPSPDSPDAAPEARPRPRRRPRPPA-GSPARSPA 469 >gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo sapiens] Length = 1059 Score = 36.2 bits (82), Expect = 0.039 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 10/109 (9%) Query: 207 SSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEAPRMGFTHPPGH-----LS 261 SS S S S SSSS S+ + +K D P + G+ P P LS Sbjct: 94 SSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLS 153 Query: 262 GCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGP 310 G Q + + G ++ P G PGL A PG PA P GP Sbjct: 154 GHQHLFGNLKRGGPASGP--GVTPGLGAPA---GAPGPLPAPSQTPPGP 197 >gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo sapiens] Length = 1059 Score = 36.2 bits (82), Expect = 0.039 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 10/109 (9%) Query: 207 SSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEAPRMGFTHPPGH-----LS 261 SS S S S SSSS S+ + +K D P + G+ P P LS Sbjct: 94 SSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLS 153 Query: 262 GCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGP 310 G Q + + G ++ P G PGL A PG PA P GP Sbjct: 154 GHQHLFGNLKRGGPASGP--GVTPGLGAPA---GAPGPLPAPSQTPPGP 197 >gi|89051034 PREDICTED: methyl-CpG-binding domain protein 3-like 3-like [Homo sapiens] Length = 208 Score = 36.2 bits (82), Expect = 0.039 Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 14/97 (14%) Query: 226 PSTGVRDRKGDKPWKESGGSVEAPRMGFTHP---------PGHLSGCQSSLASGETGTGS 276 P VR RKGD+ ++ R+ P P HL S LA G G S Sbjct: 68 PDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGE-S 126 Query: 277 ADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSC 313 D G R R+P++ TPGR PA P C Sbjct: 127 LDRAGAERV----RSPLEPTPGRFPAVAGGPTPGMGC 159 >gi|113428063 PREDICTED: similar to methyl-CpG binding domain protein 3-like 2 [Homo sapiens] Length = 204 Score = 36.2 bits (82), Expect = 0.039 Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 14/97 (14%) Query: 226 PSTGVRDRKGDKPWKESGGSVEAPRMGFTHP---------PGHLSGCQSSLASGETGTGS 276 P VR RKGD+ ++ R+ P P HL S LA G G S Sbjct: 68 PDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGE-S 126 Query: 277 ADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSC 313 D G R R+P++ TPGR PA P C Sbjct: 127 LDRAGAERV----RSPLEPTPGRFPAVAGGPTPGMGC 159 >gi|38683860 insulin receptor substrate 2 [Homo sapiens] Length = 1338 Score = 36.2 bits (82), Expect = 0.039 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Query: 242 SGGSVEAPR---MGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPG 298 +GG+++ R M H P + S +S G+GS PP GP P L P+ PG Sbjct: 421 AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPH--PLHHGPG 478 Query: 299 RAPAADAAPAGPS 311 + P++ +A A S Sbjct: 479 QRPSSGSASASGS 491 >gi|157389003 methyl-CpG binding domain protein 3-like 2 [Homo sapiens] Length = 208 Score = 36.2 bits (82), Expect = 0.039 Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 14/97 (14%) Query: 226 PSTGVRDRKGDKPWKESGGSVEAPRMGFTHP---------PGHLSGCQSSLASGETGTGS 276 P VR RKGD+ ++ R+ P P HL S LA G G S Sbjct: 68 PDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGE-S 126 Query: 277 ADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSC 313 D G R R+P++ TPGR PA P C Sbjct: 127 LDRAGAERV----RSPLEPTPGRFPAVAGGPTPGMGC 159 >gi|169217724 PREDICTED: similar to methyl-CpG binding domain protein 3-like 2, partial [Homo sapiens] Length = 193 Score = 35.8 bits (81), Expect = 0.051 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 14/97 (14%) Query: 226 PSTGVRDRKGD----KP-----WKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGS 276 P VR RKGD KP +++ G P HL S LA G T + S Sbjct: 53 PDNQVRRRKGDEHLEKPQQLCAYRKLQALQPCSSQGEGSSPLHLESVLSILAPG-TASES 111 Query: 277 ADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSC 313 D G R R+P++ TPGR PA P C Sbjct: 112 LDRAGAERV----RSPLEPTPGRFPAVAGGPTPGMGC 144 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,596,041 Number of Sequences: 37866 Number of extensions: 903589 Number of successful extensions: 5257 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 241 Number of HSP's that attempted gapping in prelim test: 4936 Number of HSP's gapped (non-prelim): 564 length of query: 315 length of database: 18,247,518 effective HSP length: 102 effective length of query: 213 effective length of database: 14,385,186 effective search space: 3064044618 effective search space used: 3064044618 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.