BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5901980 heat shock transcription factor 2 binding protein [Homo sapiens] (334 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5901980 heat shock transcription factor 2 binding protein [Ho... 646 0.0 gi|221316624 dystonin isoform 4 [Homo sapiens] 45 1e-04 gi|221316622 dystonin isoform 3 [Homo sapiens] 45 1e-04 gi|221316618 dystonin isoform 2 [Homo sapiens] 45 1e-04 gi|34577047 dystonin isoform 1 [Homo sapiens] 45 1e-04 gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] 45 1e-04 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 42 6e-04 gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 42 0.001 gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 41 0.001 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 40 0.002 gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 40 0.003 gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 40 0.003 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 39 0.008 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 39 0.008 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 39 0.008 gi|21361440 RAB3A interacting protein (rabin3)-like 1 [Homo sapi... 39 0.008 gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 38 0.011 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 38 0.014 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 37 0.019 gi|50083279 centrosome protein 4 [Homo sapiens] 37 0.019 gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens] 37 0.025 gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s... 37 0.025 gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s... 37 0.025 gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] 37 0.025 gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 37 0.025 gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 37 0.025 gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 37 0.025 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 37 0.025 gi|45505178 cancer antigen 1 [Homo sapiens] 37 0.032 gi|215982794 myosin VA isoform 2 [Homo sapiens] 37 0.032 >gi|5901980 heat shock transcription factor 2 binding protein [Homo sapiens] Length = 334 Score = 646 bits (1666), Expect = 0.0 Identities = 334/334 (100%), Positives = 334/334 (100%) Query: 1 MGEAGAAEEACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIV 60 MGEAGAAEEACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIV Sbjct: 1 MGEAGAAEEACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIV 60 Query: 61 EKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYC 120 EKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYC Sbjct: 61 EKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYC 120 Query: 121 TEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDGDVQELDSDES 180 TEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDGDVQELDSDES Sbjct: 121 TEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDGDVQELDSDES 180 Query: 181 QFVFALAGIVTNVAAIACGREFLVNSSRVLLDTILQLLGDLKPGQCTKLKVLMLMSLYNV 240 QFVFALAGIVTNVAAIACGREFLVNSSRVLLDTILQLLGDLKPGQCTKLKVLMLMSLYNV Sbjct: 181 QFVFALAGIVTNVAAIACGREFLVNSSRVLLDTILQLLGDLKPGQCTKLKVLMLMSLYNV 240 Query: 241 SINLKGLKYISESPGFIPLLWWLLSDPDAEVCLHVLRLVQSVVLEPEVFSKSASEFRSSL 300 SINLKGLKYISESPGFIPLLWWLLSDPDAEVCLHVLRLVQSVVLEPEVFSKSASEFRSSL Sbjct: 241 SINLKGLKYISESPGFIPLLWWLLSDPDAEVCLHVLRLVQSVVLEPEVFSKSASEFRSSL 300 Query: 301 PLQRILAMSKSRNPRLQTAAQELLEDLRTLEHNV 334 PLQRILAMSKSRNPRLQTAAQELLEDLRTLEHNV Sbjct: 301 PLQRILAMSKSRNPRLQTAAQELLEDLRTLEHNV 334 >gi|221316624 dystonin isoform 4 [Homo sapiens] Length = 5526 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 9 EACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKE 68 E ++ +EE K + + L V +FL NGE L K ++E+ L + Sbjct: 1621 ELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLKE--NGEKLSQEDKA-LIEQKLNEAK 1677 Query: 69 QELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 + EQL + E K L+ V I+E+ EK+A +QL E+K ++ Sbjct: 1678 IKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKI 1722 >gi|221316622 dystonin isoform 3 [Homo sapiens] Length = 5537 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 9 EACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKE 68 E ++ +EE K + + L V +FL NGE L K ++E+ L + Sbjct: 1632 ELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLKE--NGEKLSQEDKA-LIEQKLNEAK 1688 Query: 69 QELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 + EQL + E K L+ V I+E+ EK+A +QL E+K ++ Sbjct: 1689 IKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKI 1733 >gi|221316618 dystonin isoform 2 [Homo sapiens] Length = 5675 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 9 EACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKE 68 E ++ +EE K + + L V +FL NGE L K ++E+ L + Sbjct: 1770 ELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLKE--NGEKLSQEDKA-LIEQKLNEAK 1826 Query: 69 QELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 + EQL + E K L+ V I+E+ EK+A +QL E+K ++ Sbjct: 1827 IKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKI 1871 >gi|34577047 dystonin isoform 1 [Homo sapiens] Length = 5497 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 9 EACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKE 68 E ++ +EE K + + L V +FL NGE L K ++E+ L + Sbjct: 1592 ELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLKE--NGEKLSQEDKA-LIEQKLNEAK 1648 Query: 69 QELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 + EQL + E K L+ V I+E+ EK+A +QL E+K ++ Sbjct: 1649 IKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKI 1693 >gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] Length = 5171 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 9 EACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKE 68 E ++ +EE K + + L V +FL NGE L K ++E+ L + Sbjct: 1266 ELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLKE--NGEKLSQEDKA-LIEQKLNEAK 1322 Query: 69 QELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 + EQL + E K L+ V I+E+ EK+A +QL E+K ++ Sbjct: 1323 IKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKI 1367 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 42.4 bits (98), Expect = 6e-04 Identities = 46/186 (24%), Positives = 77/186 (41%), Gaps = 6/186 (3%) Query: 3 EAGAAEEACRHMGTKEE--FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIV 60 EAG A A M K E F K+R+ DLE T + L + V E +++ + Sbjct: 1156 EAGGATSAQIEMNKKREAEFQKMRR-DLEESTLQHEATAAALRKKHADSVAELGEQIDSL 1214 Query: 61 EKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYC 120 ++ ++ E+E +LKM+ + +ETV +K L QL+E K + +Q Sbjct: 1215 QRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLI 1274 Query: 121 TEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDGDVQELDSDES 180 E+ A L + S E + + D + S Q ++ L ++E +S Sbjct: 1275 NELSAQKARL---HTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKS 1331 Query: 181 QFVFAL 186 AL Sbjct: 1332 TLAHAL 1337 Score = 33.1 bits (74), Expect = 0.36 Identities = 41/176 (23%), Positives = 82/176 (46%), Gaps = 36/176 (20%) Query: 21 VKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERK-----EQ------ 69 ++ +K+ L+TE+ ++++ E L+ + LK KNL+++ EQ Sbjct: 1471 LEASQKESRSLSTELFKVKNAYE-----ESLDHLETLKRENKNLQQEISDLTEQIAEGGK 1525 Query: 70 ---ELEQLKMDCEHFKARLET----VQADNIREKKEKLALRQQLNEAKQQLLQQ-AEYCT 121 ELE++K +H K+ L+T +A E+ + L ++ +LN+ K ++ ++ AE Sbjct: 1526 HIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDE 1585 Query: 122 EMGAAACTLLWGVSSSEEVVKA-ILGGDKALKFFSITGQTMESFVKSLDGDVQELD 176 E+ L V S + + A I + AL+ K ++GD+ E++ Sbjct: 1586 ELDQLKRNHLRVVESMQSTLDAEIRSRNDALR-----------IKKKMEGDLNEME 1630 Score = 31.2 bits (69), Expect = 1.4 Identities = 33/183 (18%), Positives = 75/183 (40%), Gaps = 14/183 (7%) Query: 51 LESFQKLKIVEKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAK 110 LE Q +++ + K++EL+QLK + +++ IR + + L +++++ Sbjct: 1567 LELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDL 1626 Query: 111 QQLLQQAEYCTEMGAAACTLLWGVSSSEEVVK--------AILGGD---KALKFFSITGQ 159 ++ Q + A A L + +++ ++K AI G D + L Sbjct: 1627 NEMEIQLNHANRQAAEA---LRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRAN 1683 Query: 160 TMESFVKSLDGDVQELDSDESQFVFALAGIVTNVAAIACGREFLVNSSRVLLDTILQLLG 219 M++ V+ L ++ + L V + L+N+ + L I Q+ G Sbjct: 1684 LMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQG 1743 Query: 220 DLK 222 +++ Sbjct: 1744 EME 1746 >gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] Length = 1780 Score = 41.6 bits (96), Expect = 0.001 Identities = 24/104 (23%), Positives = 60/104 (57%), Gaps = 1/104 (0%) Query: 12 RHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKEQEL 71 R++ +E ++ K+ + L + +++++ + ++ N + + L++ E+ E QE Sbjct: 1159 RNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNN-LQDMKHLLQLKEEEEETNRQET 1217 Query: 72 EQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQ 115 E+LK + AR + ++AD R++++ L+++L +AK+Q+ Q Sbjct: 1218 EKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQ 1261 Score = 32.0 bits (71), Expect = 0.79 Identities = 29/135 (21%), Positives = 66/135 (48%), Gaps = 2/135 (1%) Query: 46 LNGEVLESFQKLKIVEKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQ 105 L E+ S + + ++ +L+RKE++ LK K +++ VQ + + E LR + Sbjct: 1220 LKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIK 1279 Query: 106 LNEAKQQLLQQAEYCTEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFV 165 +NE +++ Q +M L ++++V +AI ++A K ++ + +E Sbjct: 1280 INELEKK-KNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMR 1338 Query: 166 KSLDGDVQ-ELDSDE 179 +L+ Q +++ D+ Sbjct: 1339 MTLEEQEQTQVEQDQ 1353 Score = 30.8 bits (68), Expect = 1.8 Identities = 26/122 (21%), Positives = 58/122 (47%), Gaps = 11/122 (9%) Query: 2 GEAGAAEEACRHMGTKEEFVKVRKKDL--ERLTTEVMQIRDFLPRILNGEVLESFQKLKI 59 G ++++ + + + V++ + E ++M+ D + + N E ++ + K+ Sbjct: 494 GPVKSSQDVSLDSNSNSKILNVKRATISWENSLEDLMEDEDLVEELENAEETQNVET-KL 552 Query: 60 VEKNLERKEQELEQLKMDCEHFKAR-----LETVQADNIREKKEKLALRQQLNEAKQQLL 114 ++++L++ LE+ K H + R +E ++ I EKKEKL L ++ E Q Sbjct: 553 LDEDLDKT---LEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEVTQEF 609 Query: 115 QQ 116 Q Sbjct: 610 TQ 611 >gi|210032790 hypothetical protein LOC27146 [Homo sapiens] Length = 1060 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/180 (20%), Positives = 85/180 (47%), Gaps = 27/180 (15%) Query: 3 EAGAAEEACRHMGTKEEFVKVRKKDLERLTT---EVMQIR-DFLPRILNGEVLESFQKLK 58 E AE A + TKE ++V + ER+ T E+++++ D+ R+ + E+ + + Sbjct: 116 EEALAESASCRLETKERELRVEAEHAERVLTLSREMLELKADYERRLQHLTSHEATPQGR 175 Query: 59 IVEKNLERKEQ-----ELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 + +++ E K + E++++ ++ + + + + D R+ +E A ++ NEA +Q Sbjct: 176 LPQESPETKSEPGQGPEMQEVLLEVQRLRVENQQLSKDYARKAEELQATYERENEAIRQA 235 Query: 114 LQQAEYCTEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDGDVQ 173 +QQ + LW E ++ K F + +++ V+ L+GD++ Sbjct: 236 MQQ---------SVSQALWQWQEKESDLR---------KNFQVQESALQAQVRKLEGDLE 277 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 40.4 bits (93), Expect = 0.002 Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 3/130 (2%) Query: 3 EAGAAEEACRHMGTKEE--FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIV 60 EAG A A M K E F K+R+ DLE T + L + V E +++ + Sbjct: 1156 EAGGATSAQIEMNKKREAEFQKMRR-DLEEATLQHEATAATLRKKHADSVAELGEQIDNL 1214 Query: 61 EKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYC 120 ++ ++ E+E ++KM+ + + +ETV +K AL QL+E K + +Q Sbjct: 1215 QRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLI 1274 Query: 121 TEMGAAACTL 130 ++ A L Sbjct: 1275 NDLTAQRARL 1284 Score = 36.6 bits (83), Expect = 0.032 Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%) Query: 9 EACRHMGTKEEFVKVRKKDLERLTTEV-MQIRDFLPRI-----LNGEVLESFQKLKIVEK 62 ++ +G + + ++ K+ LE+ +E+ M+I D + G + + + L+ Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLS 1261 Query: 63 NLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAE 118 ++ KE+E ++L D +ARL+T + R+ EK L QL+ KQ QQ E Sbjct: 1262 EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIE 1317 Score = 29.3 bits (64), Expect = 5.2 Identities = 27/116 (23%), Positives = 59/116 (50%), Gaps = 14/116 (12%) Query: 3 EAGAAEEACRHMGTKEEFVKVR---KKDLERLTTEVMQIRDFLPRI--LNGEVLESFQKL 57 E A+++ R + T E K++ ++ L++L T + ++ I L ++ E +++ Sbjct: 1470 ELEASQKESRSLST--ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1527 Query: 58 KIVEKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 +EK ++ EQE +L+ E +A LE E+ + L ++ +LN+ K ++ Sbjct: 1528 HELEKIKKQVEQEKSELQAALEEAEASLE-------HEEGKILRIQLELNQVKSEV 1576 >gi|237858621 polyamine modulated factor 1 binding protein 1 isoform b [Homo sapiens] Length = 882 Score = 40.0 bits (92), Expect = 0.003 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 15/138 (10%) Query: 5 GAAEEACRHMGTKEEFVKV---RKKDLERLTTEVMQIRDFLPRILN--GEVLESFQK-LK 58 G EE H+ K++ + + R ++L+ TE ++ + L E+L+ +K L Sbjct: 214 GLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLT 273 Query: 59 IVEKNLERKEQELEQLKMDCEHFKARLETVQADNIRE------KKEKLALRQQLNEAKQQ 112 V+ +L +KE+ELE+ + + ++ + D +E + E L+ L EAKQQ Sbjct: 274 QVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQ 333 Query: 113 ---LLQQAEYCTEMGAAA 127 QQA C E A A Sbjct: 334 ERLAAQQAAQCKEEAALA 351 Score = 28.9 bits (63), Expect = 6.7 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 25 KKDLERLTTEV-MQIRDFLPRILNGEVLESFQKLKIVEKNLERK---EQELEQLKMDCEH 80 K+ L++ E M++ D L RI + + K K+ E E E + EQLK EH Sbjct: 425 KRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEH 484 Query: 81 FKARLETVQADNIREKKEKLALRQ---QLNEAKQQLLQQAEYCT 121 K ++A KK+ L++ +L E + L + + C+ Sbjct: 485 EKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCS 528 >gi|237858619 polyamine modulated factor 1 binding protein 1 isoform a [Homo sapiens] Length = 1007 Score = 40.0 bits (92), Expect = 0.003 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 15/138 (10%) Query: 5 GAAEEACRHMGTKEEFVKV---RKKDLERLTTEVMQIRDFLPRILN--GEVLESFQK-LK 58 G EE H+ K++ + + R ++L+ TE ++ + L E+L+ +K L Sbjct: 359 GLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLT 418 Query: 59 IVEKNLERKEQELEQLKMDCEHFKARLETVQADNIRE------KKEKLALRQQLNEAKQQ 112 V+ +L +KE+ELE+ + + ++ + D +E + E L+ L EAKQQ Sbjct: 419 QVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQ 478 Query: 113 ---LLQQAEYCTEMGAAA 127 QQA C E A A Sbjct: 479 ERLAAQQAAQCKEEAALA 496 Score = 28.9 bits (63), Expect = 6.7 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 25 KKDLERLTTEV-MQIRDFLPRILNGEVLESFQKLKIVEKNLERK---EQELEQLKMDCEH 80 K+ L++ E M++ D L RI + + K K+ E E E + EQLK EH Sbjct: 570 KRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEH 629 Query: 81 FKARLETVQADNIREKKEKLALRQ---QLNEAKQQLLQQAEYCT 121 K ++A KK+ L++ +L E + L + + C+ Sbjct: 630 EKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCS 673 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 38.5 bits (88), Expect = 0.008 Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 11/111 (9%) Query: 14 MGTKEEFVKVRKKDL---ERLTT-EVMQIRDFLPRILNGEVLESFQKL----KIVEKNLE 65 M +EE VKVR+K L RLT E +Q + ++ E L++ +L + + L Sbjct: 848 MAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLT 907 Query: 66 RKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQ 116 K+QELE++ C +AR+E + + EK ++Q + E ++QL ++ Sbjct: 908 AKKQELEEI---CHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEE 955 Score = 29.6 bits (65), Expect = 3.9 Identities = 40/170 (23%), Positives = 80/170 (47%), Gaps = 8/170 (4%) Query: 8 EEACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERK 67 + CR ++ F K R++ L + +L ++ N + F K+K + L+ Sbjct: 787 QACCRGYLARKAFAK-RQQQLTAMKVLQRNCAAYL-KLRNWQWWRLFTKVKPL---LQVS 841 Query: 68 EQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTEMGAAA 127 QE E + + E K R + + A+N + E L+ QL K QL +Q + TE+ A A Sbjct: 842 RQEEEMMAKEEELVKVREKQLAAENRLTEME--TLQSQLMAEKLQLQEQLQAETELCAEA 899 Query: 128 CTLLWGVSSSEEVVKAILGGDKA-LKFFSITGQTMESFVKSLDGDVQELD 176 L +++ ++ ++ I +A ++ Q +++ K + ++QEL+ Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949 Score = 29.6 bits (65), Expect = 3.9 Identities = 38/183 (20%), Positives = 85/183 (46%), Gaps = 24/183 (13%) Query: 8 EEACRHMGTKEEFVKVRKKDLERLTT---EVMQIRDFLPRILN------GEVLESFQKLK 58 E++ + T EE + +KDLE L+ E + D L + ++L + Sbjct: 1374 EDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQR 1433 Query: 59 IVEKNLERKEQELEQLKMDCEHFKARL----ETVQADNIREKKEKLALRQQLNEAKQQLL 114 NLE+K+++ +QL + + A+ + +A+ ++ + L+L + L EA +Q Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA 1493 Query: 115 Q----QAEYCTEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDG 170 + ++ TEM +SS ++V K++ +K+ + + M++ ++ L+ Sbjct: 1494 ELERLNKQFRTEMEDL-------MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELED 1546 Query: 171 DVQ 173 ++Q Sbjct: 1547 ELQ 1549 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 38.5 bits (88), Expect = 0.008 Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 3/125 (2%) Query: 3 EAGAAEEACRHMGTKEE--FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIV 60 EAG A A M K E F K+R+ DLE T + L + V E +++ + Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRR-DLEEATLQHEATAATLRKKHADSVAELGEQIDNL 1216 Query: 61 EKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYC 120 ++ ++ E+E ++KM+ + + +ETV +K L QL+E K + +Q Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276 Query: 121 TEMGA 125 ++ A Sbjct: 1277 NDLTA 1281 Score = 38.1 bits (87), Expect = 0.011 Identities = 31/116 (26%), Positives = 57/116 (49%), Gaps = 6/116 (5%) Query: 9 EACRHMGTKEEFVKVRKKDLERLTTEV-MQIRDFLPRI-----LNGEVLESFQKLKIVEK 62 ++ +G + + ++ K+ LE+ +E+ M+I D + G + + + L+ Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263 Query: 63 NLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAE 118 L+ KE+E ++L D + RL+T + R+ EK AL QL+ KQ QQ E Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIE 1319 Score = 30.8 bits (68), Expect = 1.8 Identities = 29/116 (25%), Positives = 60/116 (51%), Gaps = 14/116 (12%) Query: 3 EAGAAEEACRHMGTKEEFVKVR---KKDLERLTTEVMQIRDFLPRI--LNGEVLESFQKL 57 E A+++ R +GT E K++ ++ L++L T + ++ I L ++ E +++ Sbjct: 1472 ELEASQKEARSLGT--ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1529 Query: 58 KIVEKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 +EK ++ EQE CE +A LE +A E+ + L ++ +LN+ K ++ Sbjct: 1530 HELEKIKKQVEQE------KCE-LQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 38.5 bits (88), Expect = 0.008 Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 3/125 (2%) Query: 3 EAGAAEEACRHMGTKEE--FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIV 60 EAG A A M K E F K+R+ DLE T + L + V E +++ + Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRR-DLEEATLQHEATAATLRKKHADSVAELGEQIDNL 1216 Query: 61 EKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYC 120 ++ ++ E+E ++KM+ + + +ETV +K L QL+E K + +Q Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276 Query: 121 TEMGA 125 ++ A Sbjct: 1277 NDLTA 1281 Score = 38.1 bits (87), Expect = 0.011 Identities = 31/116 (26%), Positives = 57/116 (49%), Gaps = 6/116 (5%) Query: 9 EACRHMGTKEEFVKVRKKDLERLTTEV-MQIRDFLPRI-----LNGEVLESFQKLKIVEK 62 ++ +G + + ++ K+ LE+ +E+ M+I D + G + + + L+ Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLS 1263 Query: 63 NLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAE 118 L+ KE+E ++L D + RL+T + R+ EK AL QL+ KQ QQ E Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIE 1319 Score = 30.8 bits (68), Expect = 1.8 Identities = 29/116 (25%), Positives = 60/116 (51%), Gaps = 14/116 (12%) Query: 3 EAGAAEEACRHMGTKEEFVKVR---KKDLERLTTEVMQIRDFLPRI--LNGEVLESFQKL 57 E A+++ R +GT E K++ ++ L++L T + ++ I L ++ E +++ Sbjct: 1472 ELEASQKEARSLGT--ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1529 Query: 58 KIVEKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 +EK ++ EQE CE +A LE +A E+ + L ++ +LN+ K ++ Sbjct: 1530 HELEKIKKQVEQE------KCE-LQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578 >gi|21361440 RAB3A interacting protein (rabin3)-like 1 [Homo sapiens] Length = 382 Score = 38.5 bits (88), Expect = 0.008 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 7/118 (5%) Query: 3 EAGAAEEACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEK 62 E A EEA +E + D+ RL + M+IR+ L E+ + ++LK+ ++ Sbjct: 41 ETSAGEEA-----QGQEGPAAAQLDVLRLRSSSMEIREKGSEFLKEELHRAQKELKLKDE 95 Query: 63 NLERKEQELEQLKMDCEHFKARLETVQADNIREKKEK-LALRQQLNEAKQQL-LQQAE 118 ER + EQL+ + E A L +RE K A +QL EA+ ++ + QAE Sbjct: 96 ECERLSKVREQLEQELEELTASLFEEAHKMVREANMKQAASEKQLKEARGKIDMLQAE 153 >gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] Length = 1217 Score = 38.1 bits (87), Expect = 0.011 Identities = 44/172 (25%), Positives = 78/172 (45%), Gaps = 29/172 (16%) Query: 60 VEKNLERKEQELEQLKMDCEHFKARLETVQA--DNIREKKEKLALRQQLNE----AKQQL 113 + +N+ER E++QL + + + +A D+I + + L ++Q +E KQ+ Sbjct: 700 LRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRS 759 Query: 114 LQQAEYCTEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDGDVQ 173 LQ E L + S+ E +KA LG D L S+ Q V +L+ +++ Sbjct: 760 LQSLE----------ASLHAMESTRESLKAELGTD-LLSQLSLEDQKR---VDALNDEIR 805 Query: 174 ELDSDESQFV---FALAGIVTNVAAIACGREFLVNSSRVLLDTILQLLGDLK 222 +L + Q + L GI+T V +L + R LD + Q L +L+ Sbjct: 806 QLQQENRQLLNERIKLEGIITRV------ETYLNENLRKRLDQVEQELNELR 851 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 37.7 bits (86), Expect = 0.014 Identities = 39/136 (28%), Positives = 68/136 (50%), Gaps = 21/136 (15%) Query: 1 MGEAGAAEEACRHMGTK-EEFVKVRKKDLER----LTTEVMQIRDFLPRILNGEVLESFQ 55 + A EEA R + + +E +K +K E L E+ +++ + ++ E Sbjct: 420 LSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA 479 Query: 56 KL-KIVEKNLERKEQEL------------EQLKMDCEHFKARLETVQADNIREKKEKLAL 102 KL K+ EK L RKEQEL EQ+K+ E K++ E ++ +E++E LAL Sbjct: 480 KLQKLHEKELARKEQELTKKLQTREREFQEQMKVALE--KSQSEYLKISQEKEQQESLAL 537 Query: 103 RQQLNEAKQQLLQQAE 118 ++L K+ +L ++E Sbjct: 538 -EELELQKKAILTESE 552 Score = 33.5 bits (75), Expect = 0.27 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 26/114 (22%) Query: 18 EEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVE------KNLERKEQEL 71 +E K++ + T + Q+RD I E LE + + I E + LE KE+E+ Sbjct: 328 QELEKIKDLHMAEKTKLITQLRDAKNLI---EQLEQDKGMVIAETKRQMHETLEMKEEEI 384 Query: 72 EQLKMDCEHFKARLETVQADNIREKKEK------------LALRQQLNEAKQQL 113 QL+ + + T Q + +RE+KEK L+ Q+ EA+++L Sbjct: 385 AQLRS-----RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 433 Score = 30.8 bits (68), Expect = 1.8 Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 7/104 (6%) Query: 24 RKKDLERLTT----EVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKEQELEQLKMDCE 79 +K+ +E LT E+ + + LN + E Q++ ++ L+ KEQE+ +LK Sbjct: 1025 QKEQIESLTEVHRRELNDVISIWEKKLNQQA-EELQEIHEIQ--LQEKEQEVAELKQKIL 1081 Query: 80 HFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTEM 123 F E + + K+E + LNE ++QL Q++ + + Sbjct: 1082 LFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSL 1125 Score = 30.0 bits (66), Expect = 3.0 Identities = 19/106 (17%), Positives = 59/106 (55%), Gaps = 10/106 (9%) Query: 17 KEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKEQELEQLKM 76 KEE + + ++++TT+ ++R+ + +F++L+ ++ E+ +LK Sbjct: 380 KEEEIAQLRSRIKQMTTQGEELREQKEKSERA----AFEELEKALSTAQKTEEARRKLKA 435 Query: 77 DCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTE 122 + + +++T++ + ++E+++L+Q+L+ KQ+++ + +E Sbjct: 436 EMDE---QIKTIEKTS---EEERISLQQELSRVKQEVVDVMKKSSE 475 Score = 30.0 bits (66), Expect = 3.0 Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 19/111 (17%) Query: 24 RKKDLERLTTEVMQIRDF--LPRILNGEVLESFQKLKIVEKNLERKEQELEQLKMDCEH- 80 ++KD+E V +++ F L + V E+ +K+ +E + + ELE K + EH Sbjct: 1553 QQKDIEHKEL-VQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHV 1611 Query: 81 -------------FKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAE 118 + RLE+ A + E K K Q++ K+QLL Q E Sbjct: 1612 NLSVKSKEEELKALEDRLESESAAKLAELKRK--AEQKIAAIKKQLLSQME 1660 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 37.4 bits (85), Expect = 0.019 Identities = 39/218 (17%), Positives = 95/218 (43%), Gaps = 23/218 (10%) Query: 13 HMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKEQELE 72 H+ T + ++ ++++L ++TT++ Q+ ++ + + +E +L+ +++ Sbjct: 668 HLDTAQNALQDKQQELNKITTQLDQV--------TAKLQDKQEHCSQLESHLKEYKEKYL 719 Query: 73 QLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTEMGAAACTLLW 132 L+ E + +++ ++AD++ K K +A Q L QQ + T++ A L Sbjct: 720 SLEQKTEELEGQIKKLEADSLEVKASK-------EQALQDLQQQRQLNTDLELRATELSK 772 Query: 133 GVSSSEEVVKA----ILGGDKALKFF--SITGQTMESFVKSLDGDV--QELDSDESQFVF 184 + +E+V + + +AL+ +T Q E + D + QE + Sbjct: 773 QLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN 832 Query: 185 ALAGIVTNVAAIACGREFLVNSSRVLLDTILQLLGDLK 222 + VT + + +E L+ + D + ++ LK Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLK 870 Score = 35.8 bits (81), Expect = 0.055 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 13/107 (12%) Query: 16 TKEEFVKVRKK------DLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKEQ 69 +K EF K +K DLE+ E L L ++ + ++ K ++K+LE++++ Sbjct: 872 SKSEFEKENQKGKAAILDLEKTCKE-------LKHQLQVQMENTLKEQKELKKSLEKEKE 924 Query: 70 ELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQ 116 QLK++ + +L Q + +KE+ L+ +NE KQ Q+ Sbjct: 925 ASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQK 971 Score = 30.4 bits (67), Expect = 2.3 Identities = 37/180 (20%), Positives = 78/180 (43%), Gaps = 15/180 (8%) Query: 65 ERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTEMG 124 ++ ++EL +++ +H KA + +Q +++ L L+ ++N+ +LL+ ++G Sbjct: 375 QKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETER---QLG 431 Query: 125 AAACTL--LWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDGDVQELDSDESQF 182 A L +SS + + K D LK + Q E S + +LD + Q Sbjct: 432 EAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQ-HQLDKTKQQH 490 Query: 183 VFALAGIVTNVAAIACGREFLVNSSRVLLDTILQLLGDLKPGQCTKLKVLMLMSLYNVSI 242 A+ + ++ L+ +L+ +GD K + L+ L+ S N+S+ Sbjct: 491 --------QEQQALQQSTTAKLREAQNDLEQVLRQIGD-KDQKIQNLEALLQKSKENISL 541 Score = 28.5 bits (62), Expect = 8.8 Identities = 33/130 (25%), Positives = 58/130 (44%), Gaps = 24/130 (18%) Query: 8 EEACRHMGTKEEFVK----VRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKN 63 E+ R +G K++ ++ + +K E ++ + D +I GE E+ ++ EKN Sbjct: 512 EQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEG-ETAVLNQLQEKN 570 Query: 64 LERKEQEL---EQLKMDCEHFKARLETVQADNIREKKEKLA---------------LRQQ 105 +EQ E+LK E K E + D ++E+K L L Q Sbjct: 571 HTLQEQVTQLTEKLKNQSESHKQAQENLH-DQVQEQKAHLRAAQDRVLSLETSVNELNSQ 629 Query: 106 LNEAKQQLLQ 115 LNE+K+++ Q Sbjct: 630 LNESKEKVSQ 639 >gi|50083279 centrosome protein 4 [Homo sapiens] Length = 1140 Score = 37.4 bits (85), Expect = 0.019 Identities = 42/188 (22%), Positives = 79/188 (42%), Gaps = 10/188 (5%) Query: 8 EEACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERK 67 E+ H+ + +F++ KDLE+ E+M+ ++ + EV+ K + + + L Sbjct: 267 EKLIAHLNIQVDFLQQANKDLEKRIRELMETKE----TVTSEVVNLSNKNEKLCQELTEI 322 Query: 68 EQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTEMGAAA 127 +Q +QL+ E + + +E K KL+ Q L E +L + C + Sbjct: 323 DQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQKEKERL 382 Query: 128 CTLLWGVSSSEEVVKAILGG----DKALKFFSITGQ--TMESFVKSLDGDVQELDSDESQ 181 L S E VV + K ++ F++T + T+E L+ ++ D S+ Sbjct: 383 SDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERMRLEHGIKRRDRSPSR 442 Query: 182 FVFALAGI 189 L GI Sbjct: 443 LDTFLKGI 450 Score = 35.0 bits (79), Expect = 0.094 Identities = 24/100 (24%), Positives = 53/100 (53%), Gaps = 8/100 (8%) Query: 14 MGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKEQELEQ 73 M +++E V KK + + E +DFL ++ E +K+ +++NL KE+ + Q Sbjct: 715 MTSQDEEAHVMKKTIGVIDKE----KDFLQETVD----EKTEKIANLQENLANKEKAVAQ 766 Query: 74 LKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 +K+ ++ + ++ + +E +LR+QL+ A ++L Sbjct: 767 MKIMISECESSVNQLKETLVNRDREINSLRRQLDAAHKEL 806 >gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens] Length = 728 Score = 37.0 bits (84), Expect = 0.025 Identities = 34/136 (25%), Positives = 67/136 (49%), Gaps = 25/136 (18%) Query: 6 AAEEACRHMGTKEEFVKVRKKDLERLTTEVMQ-IRDFLPRI-----------------LN 47 AA +A R + + EF++V KK+ R TE + +R + R+ L Sbjct: 579 AALQAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLK 638 Query: 48 GEVLESFQKLKIVEKNLE------RKEQELEQLKMDCEHFKARLETVQADNIREKKEKLA 101 E LE ++ ++ +K E + ++E L++ +H +A E ++AD +RE++ + Sbjct: 639 RE-LEQARQARVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLLREREAREH 697 Query: 102 LRQQLNEAKQQLLQQA 117 L + + E ++QL +A Sbjct: 698 LEKVVKELQEQLWPRA 713 >gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo sapiens] Length = 732 Score = 37.0 bits (84), Expect = 0.025 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 9/91 (9%) Query: 42 LPRILNGEVLESFQKLKIVEKNLERKEQEL-EQLKMDCEHFKARLET--------VQADN 92 LP ++ E+L+ + LK++ KNL +K EL +L D E++K E + D+ Sbjct: 394 LPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDS 453 Query: 93 IREKKEKLALRQQLNEAKQQLLQQAEYCTEM 123 KK LR + + +++ +YCT M Sbjct: 454 QNRKKLSELLRYYTSASGDEMVSLKDYCTRM 484 >gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo sapiens] Length = 854 Score = 37.0 bits (84), Expect = 0.025 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 9/91 (9%) Query: 42 LPRILNGEVLESFQKLKIVEKNLERKEQEL-EQLKMDCEHFKARLET--------VQADN 92 LP ++ E+L+ + LK++ KNL +K EL +L D E++K E + D+ Sbjct: 516 LPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDS 575 Query: 93 IREKKEKLALRQQLNEAKQQLLQQAEYCTEM 123 KK LR + + +++ +YCT M Sbjct: 576 QNRKKLSELLRYYTSASGDEMVSLKDYCTRM 606 >gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] Length = 270 Score = 37.0 bits (84), Expect = 0.025 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 4/117 (3%) Query: 5 GAAEEACRHMGTKEE-FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQ-KLKIVEK 62 G + C H G K F K +K + L + R +L EV + Q KL+ V K Sbjct: 91 GKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGH-HTVLTEEVFKECQEKLQAVLK 149 Query: 63 NLERKEQELEQLKMDCEHFKARLE-TVQADNIREKKEKLALRQQLNEAKQQLLQQAE 118 L+++E+E E+L+ D K + VQ + R + E LR LN +Q+ LQ+ E Sbjct: 150 RLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLE 206 >gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 37.0 bits (84), Expect = 0.025 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 4/117 (3%) Query: 5 GAAEEACRHMGTKEE-FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQ-KLKIVEK 62 G + C H G K F K +K + L + R +L EV + Q KL+ V K Sbjct: 91 GKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGH-HTVLTEEVFKECQEKLQAVLK 149 Query: 63 NLERKEQELEQLKMDCEHFKARLE-TVQADNIREKKEKLALRQQLNEAKQQLLQQAE 118 L+++E+E E+L+ D K + VQ + R + E LR LN +Q+ LQ+ E Sbjct: 150 RLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLE 206 >gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 37.0 bits (84), Expect = 0.025 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 4/117 (3%) Query: 5 GAAEEACRHMGTKEE-FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQ-KLKIVEK 62 G + C H G K F K +K + L + R +L EV + Q KL+ V K Sbjct: 91 GKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGH-HTVLTEEVFKECQEKLQAVLK 149 Query: 63 NLERKEQELEQLKMDCEHFKARLE-TVQADNIREKKEKLALRQQLNEAKQQLLQQAE 118 L+++E+E E+L+ D K + VQ + R + E LR LN +Q+ LQ+ E Sbjct: 150 RLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLE 206 >gi|51477690 tripartite motif-containing 6 and tripartite motif-containing 34 [Homo sapiens] Length = 842 Score = 37.0 bits (84), Expect = 0.025 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 4/117 (3%) Query: 5 GAAEEACRHMGTKEE-FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQ-KLKIVEK 62 G + C H G K F K +K + L + R +L EV + Q KL+ V K Sbjct: 445 GKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRGH-HTVLTEEVFKECQEKLQAVLK 503 Query: 63 NLERKEQELEQLKMDCEHFKARLE-TVQADNIREKKEKLALRQQLNEAKQQLLQQAE 118 L+++E+E E+L+ D K + VQ + R + E LR LN +Q+ LQ+ E Sbjct: 504 RLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLE 560 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 37.0 bits (84), Expect = 0.025 Identities = 24/71 (33%), Positives = 38/71 (53%) Query: 48 GEVLESFQKLKIVEKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLN 107 G + + + L+ L+ KE+E ++L D +ARL+T + R+ EK AL QL+ Sbjct: 1246 GNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLS 1305 Query: 108 EAKQQLLQQAE 118 +KQ QQ E Sbjct: 1306 RSKQASTQQIE 1316 Score = 34.3 bits (77), Expect = 0.16 Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 11/134 (8%) Query: 3 EAGAAEEACRHMGTKEE--FVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIV 60 EAG A A + K E F K+R+ DLE T + + + L + +S +L Sbjct: 1155 EAGGATSAQVELNKKREAEFQKLRR-DLEEATLQ----HEAMVAALRKKHADSMAELGEQ 1209 Query: 61 EKNLERKEQELE----QLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQ 116 NL+R +Q+LE +LKM+ + + E + +K +L Q++E K + +Q Sbjct: 1210 IDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQ 1269 Query: 117 AEYCTEMGAAACTL 130 ++ A L Sbjct: 1270 QRLINDLTAQRARL 1283 Score = 28.9 bits (63), Expect = 6.7 Identities = 29/114 (25%), Positives = 59/114 (51%), Gaps = 10/114 (8%) Query: 3 EAGAAEEACRHMGTKEEFVK-VRKKDLERLTTEVMQIRDFLPRI--LNGEVLESFQKLKI 59 E A+++ R + T+ VK V ++ L++L T + ++ I L ++ E +++ Sbjct: 1469 ELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHE 1528 Query: 60 VEKNLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQL 113 +EK ++ EQE CE +A LE +A E+ + L ++ +LN+ K ++ Sbjct: 1529 LEKIKKQVEQE------KCE-IQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1575 >gi|45505178 cancer antigen 1 [Homo sapiens] Length = 641 Score = 36.6 bits (83), Expect = 0.032 Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 12/110 (10%) Query: 9 EACRHMGTKEEFVK---VRKKDLERLTTEVMQIRDFLPRILNGEVL---ESFQKLKIVEK 62 E + + KEE V+ KK+LE+ T + + E L E FQKL+ ++ Sbjct: 304 EMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLE--KE 361 Query: 63 NLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQ 112 NLE E ++LK E ++ +Q + E+ + + L+QQ+NE K + Sbjct: 362 NLE----ERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNE 407 Score = 32.0 bits (71), Expect = 0.79 Identities = 38/196 (19%), Positives = 82/196 (41%), Gaps = 26/196 (13%) Query: 14 MGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKEQELEQ 73 + +EEF K+ K++LE ++ L ++ N + + ++ K ++ + E + E Sbjct: 349 LSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNEN 408 Query: 74 LKM-------DCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTEMGAA 126 K+ + +++ + ET Q + E+ K + + LL C E Sbjct: 409 AKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEERLNP 468 Query: 127 A---------------CTLLWGVSSSEEVVKAILGGDK-ALKFFSITGQTMESF---VKS 167 A L+ G+ + ++++ + K + K I Q ++S K+ Sbjct: 469 ADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHLKKKT 528 Query: 168 LDGDVQELDSDESQFV 183 LD +V + DSDE++ + Sbjct: 529 LDKEVIDCDSDEAKSI 544 Score = 28.5 bits (62), Expect = 8.8 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 6/94 (6%) Query: 29 ERLTTEVMQIRDFLPRILNGEVL-----ESFQKLKIVEKNLERKEQE-LEQLKMDCEHFK 82 ER TE+ Q + + L + E ++L+ ++K LE+ L+ LK + E + Sbjct: 286 ERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQE 345 Query: 83 ARLETVQADNIREKKEKLALRQQLNEAKQQLLQQ 116 ++Q + + +KE L RQ+L ++LL Q Sbjct: 346 QEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQ 379 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 36.6 bits (83), Expect = 0.032 Identities = 25/98 (25%), Positives = 50/98 (51%), Gaps = 8/98 (8%) Query: 25 KKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEKNLERKEQELEQLKMDCEHFKAR 84 + DLERL Q+ + ++ G VL +++ + K+LE+ E + ++ + +K Sbjct: 965 RSDLERL-----QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019 Query: 85 LETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTE 122 E + N++E E L+Q+ +++QQA+ TE Sbjct: 1020 TEQL-VSNLKE--ENTLLKQEKEALNHRIVQQAKEMTE 1054 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.368 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,771,040 Number of Sequences: 37866 Number of extensions: 432998 Number of successful extensions: 4161 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 119 Number of HSP's successfully gapped in prelim test: 331 Number of HSP's that attempted gapping in prelim test: 2951 Number of HSP's gapped (non-prelim): 1441 length of query: 334 length of database: 18,247,518 effective HSP length: 103 effective length of query: 231 effective length of database: 14,347,320 effective search space: 3314230920 effective search space used: 3314230920 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.