Search of human proteins with 5901946

Search of human proteins with 5901946

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5901946 endothelial cell-specific molecule 1 isoform a
precursor [Homo sapiens]
         (184 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5901946 endothelial cell-specific molecule 1 isoform a precur...   402   e-113
gi|208022668 endothelial cell-specific molecule 1 isoform b prec...   268   1e-72
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]                57   1e-08
gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]           55   3e-08
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu...    54   1e-07
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu...    54   1e-07
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                52   2e-07
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]                51   5e-07
gi|22129776 HtrA serine peptidase 3 [Homo sapiens]                     50   1e-06
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]            50   1e-06
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]       50   1e-06
gi|62243290 insulin-like growth factor binding protein 4 precurs...    48   5e-06
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s...    47   1e-05
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               47   1e-05
gi|10834982 insulin-like growth factor binding protein 5 [Homo s...    46   2e-05
gi|4503123 connective tissue growth factor [Homo sapiens]              45   3e-05
gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like...    45   3e-05
gi|62243068 insulin-like growth factor binding protein 3 isoform...    45   5e-05
gi|62243248 insulin-like growth factor binding protein 3 isoform...    45   5e-05
gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ...    45   5e-05
gi|21264602 laminin alpha 5 [Homo sapiens]                             44   6e-05
gi|56090548 insulin-like growth factor binding protein-like 1 [H...    44   6e-05
gi|61743978 stabilin 1 precursor [Homo sapiens]                        44   1e-04
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo...    44   1e-04
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo...    44   1e-04
gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo sap...    43   1e-04
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ...    43   2e-04
gi|61743980 stabilin 2 precursor [Homo sapiens]                        42   3e-04
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       41   5e-04
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]       41   5e-04

>gi|5901946 endothelial cell-specific molecule 1 isoform a precursor
           [Homo sapiens]
          Length = 184

 Score =  402 bits (1034), Expect = e-113
 Identities = 184/184 (100%), Positives = 184/184 (100%)

Query: 1   MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG 60
           MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG
Sbjct: 1   MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG 60

Query: 61  RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSG 120
           RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSG
Sbjct: 61  RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSG 120

Query: 121 ICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKW 180
           ICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKW
Sbjct: 121 ICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKW 180

Query: 181 LNPR 184
           LNPR
Sbjct: 181 LNPR 184


>gi|208022668 endothelial cell-specific molecule 1 isoform b
           precursor [Homo sapiens]
          Length = 134

 Score =  268 bits (686), Expect = 1e-72
 Identities = 134/184 (72%), Positives = 134/184 (72%), Gaps = 50/184 (27%)

Query: 1   MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG 60
           MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG
Sbjct: 1   MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG 60

Query: 61  RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSG 120
           RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICK                    
Sbjct: 61  RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICK-------------------- 100

Query: 121 ICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKW 180
                                         EHDMASGDGNIVREEVVKENAAGSPVMRKW
Sbjct: 101 ------------------------------EHDMASGDGNIVREEVVKENAAGSPVMRKW 130

Query: 181 LNPR 184
           LNPR
Sbjct: 131 LNPR 134


>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
          Length = 1036

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 46/141 (32%), Positives = 64/141 (45%), Gaps = 16/141 (11%)

Query: 6   LLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDD-CGCCRVCAAGRGET 64
           LL +LL    L+A       V  P  CD S+C+    C  +++   CGCC  CA+ R E+
Sbjct: 16  LLVSLLGLLLLLARSGTRALVCLP--CDESKCEEPRNCPGSIVQGVCGCCYTCASQRNES 73

Query: 65  CYRTVSGMDGMKCGPGLRC---QPSNGEDPFGEEFGICKDCPYGTFGM----DCRET--- 114
           C  T  G+ G  C  GLRC    P NG+     E G+C+D  +    +     C E    
Sbjct: 74  CGGTF-GIYG-TCDRGLRCVIRPPLNGDSLTEYEAGVCEDENWTDDQLLGFKPCNENLIA 131

Query: 115 -CNCQSGICDRGTGKCLKFPF 134
            CN  +G C+  T +    PF
Sbjct: 132 GCNIINGKCECNTIRTCSNPF 152


>gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]
          Length = 476

 Score = 55.1 bits (131), Expect = 3e-08
 Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 7  LTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCK---RTVLDDCGCCRVCAAGRGE 63
          L  LLVP     A   +    CP  C  + C + P C      V D C CCRVC A   E
Sbjct: 19 LLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTTPVFDLCRCCRVCPAAERE 78

Query: 64 TCYRTVSGMDGMKCGPGLRC 83
           C     G  G  C PGL+C
Sbjct: 79 VC----GGAQGQPCAPGLQC 94


>gi|33598931 scavenger receptor class F, member 1 isoform 3
           precursor [Homo sapiens]
          Length = 569

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 42/125 (33%), Positives = 51/125 (40%), Gaps = 22/125 (17%)

Query: 21  SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG-RGETCYRT-VSGMDGMKCG 78
           + ++ V C   C    CK +  C      D G C  C  G  G  C +  + G  G  C 
Sbjct: 254 AGSHGVQCAHSC--GRCKHNEPCS----PDTGSCESCEPGWNGTQCQQPCLPGTFGESCE 307

Query: 79  P-------GLRCQPSNGE----DPFGEEFGICKD-CPYGTFGMDCRETC-NCQSGICDRG 125
                   G  C+P  G     DP G     C+D CP GTFG DC  TC  C  G CD  
Sbjct: 308 QQCPHCRHGEACEPDTGHCQRCDP-GWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTV 366

Query: 126 TGKCL 130
           TG C+
Sbjct: 367 TGDCV 371



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 25/109 (22%)

Query: 27  DCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS 86
           DC + C    C    +C+       G C+  A   G  C    +      CGP  RC P+
Sbjct: 98  DCRESCP---CHPHGQCEPAT----GACQCQADRWGARCEFPCA------CGPHGRCDPA 144

Query: 87  NGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGI--CDRGTGKCLKFP 133
                     G+C  C  G +   CR  C C +    C++ TG C+  P
Sbjct: 145 T---------GVC-HCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKP 183



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 28/106 (26%), Positives = 43/106 (40%), Gaps = 10/106 (9%)

Query: 31  HCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90
           HC+     S+  C+R    +    R C    G    +   G  G +C     C  S    
Sbjct: 149 HCEPGWWSST--CRRPCQCNTAAAR-CEQATGACVCKP--GWWGRRCSFRCNCHGS---- 199

Query: 91  PFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQ 136
           P  ++ G C  C  G +G +C++ C C  G C   +G+C   P F+
Sbjct: 200 PCEQDSGRCA-CRPGWWGPECQQQCECVRGRCSAASGECTCPPGFR 244



 Score = 34.3 bits (77), Expect = 0.062
 Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 8/53 (15%)

Query: 79  PGL-RCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQ-SGICDRGTGKC 129
           PGL RC+P      FG        CP   +G DCRE+C C   G C+  TG C
Sbjct: 72  PGLCRCKPGF----FGAHCS--SRCPGQYWGPDCRESCPCHPHGQCEPATGAC 118


>gi|33598929 scavenger receptor class F, member 1 isoform 1
           precursor [Homo sapiens]
          Length = 830

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 42/125 (33%), Positives = 51/125 (40%), Gaps = 22/125 (17%)

Query: 21  SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG-RGETCYRT-VSGMDGMKCG 78
           + ++ V C   C    CK +  C      D G C  C  G  G  C +  + G  G  C 
Sbjct: 254 AGSHGVQCAHSC--GRCKHNEPCS----PDTGSCESCEPGWNGTQCQQPCLPGTFGESCE 307

Query: 79  P-------GLRCQPSNGE----DPFGEEFGICKD-CPYGTFGMDCRETC-NCQSGICDRG 125
                   G  C+P  G     DP G     C+D CP GTFG DC  TC  C  G CD  
Sbjct: 308 QQCPHCRHGEACEPDTGHCQRCDP-GWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTV 366

Query: 126 TGKCL 130
           TG C+
Sbjct: 367 TGDCV 371



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 25/109 (22%)

Query: 27  DCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS 86
           DC + C    C    +C+       G C+  A   G  C    +      CGP  RC P+
Sbjct: 98  DCRESCP---CHPHGQCEPAT----GACQCQADRWGARCEFPCA------CGPHGRCDPA 144

Query: 87  NGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGI--CDRGTGKCLKFP 133
                     G+C  C  G +   CR  C C +    C++ TG C+  P
Sbjct: 145 T---------GVC-HCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKP 183



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 28/106 (26%), Positives = 43/106 (40%), Gaps = 10/106 (9%)

Query: 31  HCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90
           HC+     S+  C+R    +    R C    G    +   G  G +C     C  S    
Sbjct: 149 HCEPGWWSST--CRRPCQCNTAAAR-CEQATGACVCKP--GWWGRRCSFRCNCHGS---- 199

Query: 91  PFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQ 136
           P  ++ G C  C  G +G +C++ C C  G C   +G+C   P F+
Sbjct: 200 PCEQDSGRCA-CRPGWWGPECQQQCECVRGRCSAASGECTCPPGFR 244



 Score = 34.3 bits (77), Expect = 0.062
 Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 8/53 (15%)

Query: 79  PGL-RCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQ-SGICDRGTGKC 129
           PGL RC+P      FG        CP   +G DCRE+C C   G C+  TG C
Sbjct: 72  PGLCRCKPGF----FGAHCS--SRCPGQYWGPDCRESCPCHPHGQCEPATGAC 118


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 21/109 (19%)

Query: 28  CPQHCDSSECKSSPRCKRTVLDDC-------GCCRVCAAGRGETCYRTVSGMDGMKCGPG 80
           C +   S  CK+  R +R   + C       GC + C    G  C  +VSG  G +C  G
Sbjct: 664 CDKRDGSCSCKAGFRGERCQAE-CELGYFGPGCWQACTCPVGVAC-DSVSGECGKRCPAG 721

Query: 81  LRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKC 129
            +          GE+ G  ++CP GTFG++C  +C+C    C   TG+C
Sbjct: 722 FQ----------GEDCG--QECPVGTFGVNCSSSCSCGGAPCHGVTGQC 758



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 18   AAWSNNYAVD-CPQHCDSSECKSSPRCKRTVLDDC--GCCRVCAAGR-----GETCYRTV 69
            A W   +    CP      +C+S+  C      D   G C +C AGR      ETC    
Sbjct: 936  AGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSC-LCPAGRRGPRCAETCPAHT 994

Query: 70   SGMD---GMKCGPGLRCQPSNGE---DPFGEEFGICKDCPYGTFGMDCRETCNCQS-GIC 122
             G +      C  G  C P +G+    P        + CP G +G +CR +C CQ+ G C
Sbjct: 995  YGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC 1054

Query: 123  DRGTGKC 129
            D  +G C
Sbjct: 1055 DPVSGHC 1061



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 46/150 (30%), Positives = 58/150 (38%), Gaps = 26/150 (17%)

Query: 22  NNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCR-----VCAAGRGETCYRTVSGMD--- 73
           +++  DC   CD  +C++   C    LD C C       +C     ETC     G +   
Sbjct: 514 DSFGHDCSLTCD--DCRNGGTCLLG-LDGCDCPEGWTGLIC----NETCPPDTFGKNCSF 566

Query: 74  GMKCGPGLRCQPSNG--EDPFGEEFGICKD-CPYGTFGMDCRETCNCQS-GICDRGTGKC 129
              C  G  C    G    P G     C+D CP G +G  CR+ CNC + G C R  G C
Sbjct: 567 SCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGAC 626

Query: 130 LKFPFFQYSVTKSSNRFVSLTEHDMASGDG 159
           L  P           RF  LT    A G G
Sbjct: 627 LCDPGLY-------GRFCHLTCPPWAFGPG 649



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 39/122 (31%), Positives = 49/122 (40%), Gaps = 19/122 (15%)

Query: 21  SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGR-GETCYRTV-SGMDGMKCG 78
           + ++  DC   C+ S    S  C        G C +C AG  G  C +    G  G  C 
Sbjct: 862 TGHWGPDCSHPCNCSAGHGS--CDAI----SGLC-LCEAGYVGPRCEQQCPQGHFGPGCE 914

Query: 79  PGLRCQPSNGED--------PFGEEFGICKD-CPYGTFGMDCRETCNCQSG-ICDRGTGK 128
              +CQ     D        P G     C+  CP G FG+DCR  CNC +G  CD   G 
Sbjct: 915 QRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGS 974

Query: 129 CL 130
           CL
Sbjct: 975 CL 976



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 34/116 (29%), Positives = 43/116 (37%), Gaps = 16/116 (13%)

Query: 24   YAVDCPQHC---DSSECKSSPRCKRTVLDDCG--CCRVCAAGR-GETCYRTVSGMDGMKC 77
            Y   C Q C   +   C ++    R      G  C   C  GR G  C           C
Sbjct: 1211 YGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG------C 1264

Query: 78   GPGLRCQPSNGED--PFGEEFGIC-KDCPYGTFGMDCRETCNCQS-GICDRGTGKC 129
            G G  C P  G    P G     C + CP   FG+ C  TC+C++ G+C    G C
Sbjct: 1265 GQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSC 1320



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 34/118 (28%), Positives = 45/118 (38%), Gaps = 18/118 (15%)

Query: 24   YAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTV------SGMDGMK- 76
            Y   C   C    C ++  C+       G CR      G+ C          +G  G+  
Sbjct: 1340 YGAACHLECS---CHNNSTCEPAT----GTCRCGPGFYGQACEHPCPPGFHGAGCQGLCW 1392

Query: 77   CGPGLRCQPSNGED--PFGEEFGIC-KDCPYGTFGMDCRETCNCQSGI-CDRGTGKCL 130
            C  G  C P +G    P G     C + C  G+FG  C + C+C  G  CD  TG CL
Sbjct: 1393 CQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCL 1450



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 34/123 (27%), Positives = 44/123 (35%), Gaps = 21/123 (17%)

Query: 25   AVDCPQHCDSSECKSSPRCKRTVLDDC--GCCRVCAAGRGETCYRTV-SGMDGMKCGPGL 81
            A  CP H     C  +  C      D   G C       G +C +   +G+ G  C    
Sbjct: 987  AETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSC 1046

Query: 82   RCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETC-------NCQ-------SGICDRGTG 127
             CQ     DP     G C  CP G  G+ C + C        C+        G+CD  TG
Sbjct: 1047 LCQNGGTCDPVS---GHCA-CPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG 1102

Query: 128  KCL 130
            +CL
Sbjct: 1103 RCL 1105



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 12/84 (14%)

Query: 53  CCRVCAAG-RGETCYRTVSGMDGMKCGPGLRCQPSNGE---DPFGEEFGICKDCPYGTFG 108
           C  VC AG  G +C    S      C     C P+ G     P    F   + C  G +G
Sbjct: 813 CQDVCPAGWYGPSCQTRCS------CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG 866

Query: 109 MDCRETCNCQS--GICDRGTGKCL 130
            DC   CNC +  G CD  +G CL
Sbjct: 867 PDCSHPCNCSAGHGSCDAISGLCL 890



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 20/104 (19%)

Query: 28   CPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSN 87
            CP      +C+S   C R    +  C + C+   G  C+         +C PG       
Sbjct: 1106 CPAGWTGDKCQSP--CLRGWFGEA-CAQRCSCPPGAACHHVTGAC---RCPPGFTGS--- 1156

Query: 88   GEDPFGEEFGICKDCPYGTFGMDCRETCNC--QSGICDRGTGKC 129
                     G  + CP G+FG DC + C C  ++  C   TG C
Sbjct: 1157 ---------GCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC 1191



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 32/114 (28%), Positives = 37/114 (32%), Gaps = 19/114 (16%)

Query: 28   CPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVS-GMDGMKC-------GP 79
            C Q C    C     C        G CR      G  C +    G  G  C       G 
Sbjct: 1128 CAQRCS---CPPGAACHHVT----GACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGE 1180

Query: 80   GLRCQPSNG--EDPFGEEFGICKD-CPYGTFGMDCRETCNC-QSGICDRGTGKC 129
               C P+ G      G     C+  CP G +G  C + C C   G CD  TG C
Sbjct: 1181 NPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGAC 1234



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 11/82 (13%)

Query: 53   CCRVCAAGR-GETCYRTVSGMDGMKCGPGLRCQPSNGED--PFGEEFGICK-DCPYGTFG 108
            C R C  G  GE C++         C  G  C P  G    P G     C  DC  G FG
Sbjct: 1417 CERGCEPGSFGEGCHQRCD------CDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFG 1470

Query: 109  MDCRETCNCQSGI-CDRGTGKC 129
              C   C+C  G  CD  +G+C
Sbjct: 1471 PSCTLHCDCGGGADCDPVSGQC 1492



 Score = 34.3 bits (77), Expect = 0.062
 Identities = 30/115 (26%), Positives = 41/115 (35%), Gaps = 35/115 (30%)

Query: 53   CCRVCAAGRGETCYRTVSGMDGMKCGPG---LRCQPSNGEDPFG---------EEFGICK 100
            C  VC  G+G  C   V+G     C PG   +RC+    ++ FG            G+C 
Sbjct: 1258 CTHVCGCGQGAAC-DPVTGT--CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH 1314

Query: 101  D-------------------CPYGTFGMDCRETCNC-QSGICDRGTGKCLKFPFF 135
                                CP G +G  C   C+C  +  C+  TG C   P F
Sbjct: 1315 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGF 1369



 Score = 30.4 bits (67), Expect = 0.90
 Identities = 32/135 (23%), Positives = 45/135 (33%), Gaps = 40/135 (29%)

Query: 32  CDSSECKSSPRCKRTVLDDC---GCCRVCAAGRGETCYRTVSGMDGMKCGPGL---RCQP 85
           CD  E  +   C  T   D     C   C+   G TC  +V+G    +C PG+    C+ 
Sbjct: 540 CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC-DSVTG--ACRCPPGVSGTNCED 596

Query: 86  SNGEDPFGEE----------------FGICK------------DCPYGTFGMDCRETCNC 117
              +  +G+                 +G C              CP   FG  C E C C
Sbjct: 597 GCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQC 656

Query: 118 ---QSGICDRGTGKC 129
               +  CD+  G C
Sbjct: 657 VQPHTQSCDKRDGSC 671


>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
          Length = 1140

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 21/122 (17%)

Query: 27  DCPQHCDSSE----CKSSPRCKRTVLDD--CGCCRVCAAGRGETCY-RTVSGMDGMKCGP 79
           +C   CD       C S  +CK   L +   G C   A  RG  C  R   G  G  C  
Sbjct: 134 NCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQ 193

Query: 80  GLRCQPSNGED----------PFGEEFGICKD-CPYGTFGMDCRETCNCQS-GICDRGTG 127
             RCQ  NG            P G     C+D CP G  G  C + C CQ+ G+C   TG
Sbjct: 194 --RCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTG 251

Query: 128 KC 129
           +C
Sbjct: 252 EC 253



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 39/128 (30%), Positives = 55/128 (42%), Gaps = 23/128 (17%)

Query: 24  YAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG-RGETCYRTV--SGMDGMKCGPG 80
           Y V C + C   +C +  +C        G C +C AG  GE C   +   G+ G+KC   
Sbjct: 316 YGVLCAETC---QCVNGGKCYHV----SGAC-LCEAGFAGERCEARLCPEGLYGIKCDKR 367

Query: 81  L--------RCQPSNGE---DPFGEEFGICKDCPYGTFGMDCRETCNCQSGI-CDRGTGK 128
                     C P +GE    P        + C  G +G  C++ C+CQ+G  CD  TGK
Sbjct: 368 CPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGK 427

Query: 129 CLKFPFFQ 136
           C   P F+
Sbjct: 428 CTCAPGFK 435



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 14/116 (12%)

Query: 28  CPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGL--RCQP 85
           CP   +S E        + V   C     C    G       S  DG   GP    RCQ 
Sbjct: 95  CPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQC 154

Query: 86  SNGE--DPF--------GEEFGICKD-CPYGTFGMDCRETCNCQSG-ICDRGTGKC 129
            NG   +P         G     C+D C  GT+G DC + C CQ+G  CD  TG+C
Sbjct: 155 KNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGEC 210



 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 38/116 (32%), Positives = 50/116 (43%), Gaps = 22/116 (18%)

Query: 28  CPQHCDSSECKSSPRCKRTVLDDCGC--------C-RVCAAGR-GETCYRTVSGMDGMKC 77
           C Q C    C++   C   V  +C C        C + C  GR G+ C +     +G  C
Sbjct: 234 CEQRCP---CQNGGVCHH-VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC 289

Query: 78  GPGL-RCQPSNGEDPFGEEFGICKD-CPYGTFGMDCRETCNC-QSGICDRGTGKCL 130
                +C  S G    GE    C+D CP GT+G+ C ETC C   G C   +G CL
Sbjct: 290 DAATGQCHCSPGYT--GER---CQDECPVGTYGVLCAETCQCVNGGKCYHVSGACL 340



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 27/128 (21%)

Query: 31  HCDS--SECKSSPRCK--------RTVLDDCGCCRVCAAGRGETCYRTVS-GMDGMKCGP 79
           HCDS  +E +  P C          +   D G C      RG TC R  S G  G +C  
Sbjct: 567 HCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQ 626

Query: 80  GL-RCQPSNGEDPFGEEFGIC------------KDCPYGTFGMDCRETCNC-QSGICDRG 125
              +C  S+G  P     G+C            + CP G FG +C   C C  +G C+  
Sbjct: 627 TCPQCVHSSG--PCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPI 684

Query: 126 TGKCLKFP 133
              C  +P
Sbjct: 685 DRSCQCYP 692



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 38/131 (29%), Positives = 48/131 (36%), Gaps = 31/131 (23%)

Query: 27  DCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGP------- 79
           DC Q C  +     P C  T   +C     C+A  GE   +   G  G+ C         
Sbjct: 698 DCSQPCPPAHW--GPNCIHTC--NCHNGAFCSAYDGEC--KCTPGWTGLYCTQRCPLGFY 751

Query: 80  ----GLRCQPSNGEDPFGEEFGIC------------KDCPYGTFGMDCRETCNC-QSGIC 122
                L CQ  NG D      G C            + CP GT+G  CR+ C+C  +  C
Sbjct: 752 GKDCALICQCQNGAD-CDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTC 810

Query: 123 DRGTGKCLKFP 133
           D  TG C   P
Sbjct: 811 DHITGTCYCSP 821



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 36/124 (29%), Positives = 44/124 (35%), Gaps = 24/124 (19%)

Query: 24  YAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETC-YRTVSGMDGMKCGPGLR 82
           Y ++C   C    CK+   C        G C   A   G  C  R  SG  G  C   L 
Sbjct: 448 YGINCSSRCG---CKNDAVCSPVD----GSCTCKAGWHGVDCSIRCPSGTWGFGCN--LT 498

Query: 83  CQPSNGEDPFGEEFGICK------------DCPYGTFGMDCRETCNC-QSGICDRGTGKC 129
           CQ  NG        G C              C  GT+G++C E C+C  +  C   TG C
Sbjct: 499 CQCLNG-GACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHC 557

Query: 130 LKFP 133
              P
Sbjct: 558 RCLP 561



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 24/115 (20%)

Query: 28  CPQHCD--------SSECKSSPRCKRTVLDDCGCCRVCAAG-RGETCYRTVSGMDGMKCG 78
           CP H +        S EC   P           C   C+ G  GE C +  S      C 
Sbjct: 368 CPCHLENTHSCHPMSGECACKPGWSGLY-----CNETCSPGFYGEACQQICS------CQ 416

Query: 79  PGLRCQPSNGEDPFGEEF-GI--CKDCPYGTFGMDCRETCNCQS-GICDRGTGKC 129
            G  C    G+      F GI     CP GT+G++C   C C++  +C    G C
Sbjct: 417 NGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSC 471



 Score = 33.5 bits (75), Expect = 0.11
 Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 41/132 (31%)

Query: 20  WSNNYAVDCPQH----CDSS--ECKSSP-----RCKRTVLDDCG-------CCRVCAAGR 61
           +  N + +C  H    CD++  +C  SP     RC+    D+C        C   C    
Sbjct: 273 FGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQ----DECPVGTYGVLCAETCQCVN 328

Query: 62  GETCYRTVSGMDGMKCG-PGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNC--- 117
           G  CY  VSG    + G  G RC+               + CP G +G+ C + C C   
Sbjct: 329 GGKCYH-VSGACLCEAGFAGERCE--------------ARLCPEGLYGIKCDKRCPCHLE 373

Query: 118 QSGICDRGTGKC 129
            +  C   +G+C
Sbjct: 374 NTHSCHPMSGEC 385


>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
          Length = 453

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 27/60 (45%), Positives = 28/60 (46%), Gaps = 6/60 (10%)

Query: 25 AVDCPQHCDSSECKSSPRCKRTVLDD-CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRC 83
          A  CP  CD S C S PRC    + D C CC VCAA  GE C     G     CG  L C
Sbjct: 22 AAPCPARCDVSRCPS-PRCPGGYVPDLCNCCLVCAASEGEPC----GGPLDSPCGESLEC 76


>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
          Length = 480

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 31/84 (36%), Positives = 36/84 (42%), Gaps = 10/84 (11%)

Query: 5  LLLTTLLVPAHLV---AAWSNNYAVDCPQHCDSSECKSSPR-CKR-TVLDDCGCCRVCAA 59
          LLL  L  PA      A  S   A  CP  C+ + C   P  C+     D CGCC VC A
Sbjct: 11 LLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARDACGCCEVCGA 70

Query: 60 GRGETCYRTVSGMDGMKCGPGLRC 83
            G  C     G+    CG GL+C
Sbjct: 71 PEGAAC-----GLQEGPCGEGLQC 89


>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
          Length = 357

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 21/132 (15%)

Query: 2   KSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGR 61
           K  L LT LL+      A +      CP  C ++    +P   R VLD C CC VCA  R
Sbjct: 13  KQCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGV-RAVLDGCSCCLVCARQR 71

Query: 62  GETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGIC-----KDCPYG--------TFG 108
           GE+C    S ++      GL C  S   DP   + GIC      +C +          F 
Sbjct: 72  GESC----SDLEPCDESSGLYCDRS--ADP-SNQTGICTAVEGDNCVFDGVIYRSGEKFQ 124

Query: 109 MDCRETCNCQSG 120
             C+  C C+ G
Sbjct: 125 PSCKFQCTCRDG 136


>gi|62243290 insulin-like growth factor binding protein 4
          precursor [Homo sapiens]
          Length = 258

 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 12/90 (13%)

Query: 6  LLTTLLVPAHLVAAWSN----NYAVDCPQHCDS--SECKSSPRCKRTVLDD-CGCCRVCA 58
          +L   LV A L+AA       + A+ CP   +   + C+    C+  V +  CGCC  CA
Sbjct: 1  MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA 60

Query: 59 AGRGETCYRTVSGMDGMKCGPGLRCQPSNG 88
           G G  C     G+   +CG GLRC P  G
Sbjct: 61 LGLGMPC-----GVYTPRCGSGLRCYPPRG 85


>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
           sapiens]
          Length = 1037

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 35/130 (26%), Positives = 48/130 (36%), Gaps = 19/130 (14%)

Query: 23  NYAVDCPQHCDSSECKSSPRCKRTVL--DDCGCCRVCAAGRGETCYRTV-SGMDGMKCGP 79
           N +V CP       C +S +C    +     G C       G  C      G  G  C  
Sbjct: 476 NCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCAS 535

Query: 80  GLRCQPSNGEDPFGEEFGICK------------DCPYGTFGMDCRETCNCQS-GICDRGT 126
              C  S+G DP     G C+             CP G +G++C  TC C++ G C    
Sbjct: 536 RCDCDHSDGCDPV---HGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPEN 592

Query: 127 GKCLKFPFFQ 136
           G C+  P F+
Sbjct: 593 GNCVCAPGFR 602



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 38/131 (29%), Positives = 49/131 (37%), Gaps = 28/131 (21%)

Query: 25  AVDCPQHCDSSECKSSPRCKRTVLDD-----CGC--------CRV-CAAGR-GETCYRTV 69
           ++ CP+      C    RC    L D     C C        CR  C  GR G+ C  T 
Sbjct: 260 SLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETC 319

Query: 70  SGMDGMKCGPGLRCQPSNG----EDPFGEEFGICKDCPYGTFGMDCRETCNC---QSGIC 122
                  C P  RC P+NG    E  F  +    + CP G +G+ C+  C C    S  C
Sbjct: 320 D------CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSC 373

Query: 123 DRGTGKCLKFP 133
               G+C   P
Sbjct: 374 HPMNGECSCLP 384



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 11/83 (13%)

Query: 53  CCRVCAAGR-GETCYRTVSGMDGMKCGPGLRCQPSNGED--PFGEEFGICKD-CPYGTFG 108
           C + C  G  GE C +T       +C  G  C P +G    P G     C + CP GTFG
Sbjct: 648 CSQPCPPGHWGENCAQTC------QCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFG 701

Query: 109 MDCRETCNCQSG-ICDRGTGKCL 130
            +C + C C  G  C   TG C+
Sbjct: 702 ANCSQPCQCGPGEKCHPETGACV 724



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 38/142 (26%), Positives = 53/142 (37%), Gaps = 20/142 (14%)

Query: 28  CPQHCDSSECKSSPRCKRTVL---DDCGCCRVCAAGR-GETCYRTVSGMDGMKCGPGLRC 83
           C Q C    C +  +C+       DDC     CA G  G  C +  S      CG    C
Sbjct: 105 CAQECVHGRCVAPNQCQCVPGWRGDDCSS--ECAPGMWGPQCDKPCS------CGNNSSC 156

Query: 84  QPSNG--EDPFGEEFGIC-KDCPYGTFGMDCRETCNCQSGICDRGTGKCL-----KFPFF 135
            P +G    P G +   C + C  G +G  C+  C C    CD  TG C        P  
Sbjct: 157 DPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSC 216

Query: 136 QYSVTKSSNRFVSLTEHDMASG 157
             S ++ ++ F   + H   +G
Sbjct: 217 DVSCSQGTSGFFCPSTHSCQNG 238



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 34/118 (28%), Positives = 40/118 (33%), Gaps = 13/118 (11%)

Query: 26  VDCPQHCDSSECKSSPRCKRTVLDDC--GCCRVCAAGRGETCYRTV-SGMDGMKCGPGLR 82
           V C Q      C S+  C+   +     G C       G  C      G  G  C    R
Sbjct: 218 VSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECR 277

Query: 83  CQPSNGEDPF--------GEEFGICKD-CPYGTFGMDCRETCNC-QSGICDRGTGKCL 130
           C      D F        G     C++ CP G FG DC ETC+C     C    G CL
Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACL 335



 Score = 32.3 bits (72), Expect = 0.24
 Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 24/109 (22%)

Query: 31  HCDSSECKSSP-----RCKRTVLDDC---GCCRVCAAGRGETCYRTVSGMDGMKCGPGLR 82
           H  + EC   P      C  +   D    GC   C    G  C  T SG+   +C PG  
Sbjct: 374 HPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQAT-SGL--CQCAPGYT 430

Query: 83  CQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGI-CDRGTGKCL 130
                   P          CP  T+G++C   C+C++ I C    G+C+
Sbjct: 431 -------GPHCASL-----CPPDTYGVNCSARCSCENAIACSPIDGECV 467


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 41/121 (33%), Positives = 54/121 (44%), Gaps = 19/121 (15%)

Query: 27  DCPQHCDSSE----CKSSPRCKRTVLDD--CGCCRVCAAG-RGETCYRTVS-GMDGM--- 75
           DC   CDS      C +  +C+   L +   G C VCAAG RG  C    + G  G    
Sbjct: 128 DCSSGCDSDHWGPHCSNRCQCQNGALCNPITGAC-VCAAGFRGWRCEELCAPGTHGKGCQ 186

Query: 76  ---KCGPGLRCQPSNGEDPFGEEF-GI-CKD-CPYGTFGMDCRETCNCQS-GICDRGTGK 128
              +C  G  C P  GE      + G+ C++ CP G+ G  C   C CQ+ G C   TG+
Sbjct: 187 LPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGE 246

Query: 129 C 129
           C
Sbjct: 247 C 247



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 24/120 (20%)

Query: 24  YAVDCPQHCDSSECKSSPRCKRTVLDDC---------GCCRVCAAGR-GETCYRTVSGMD 73
           +  DC Q C    C ++  C   +   C          C + C  G  G  C+   S   
Sbjct: 659 FGQDCAQLCS---CANNGTCS-PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACS--- 711

Query: 74  GMKCGPGLRCQPSNGE---DPFGEEFGICKDCPYGTFGMDCRETCNCQSGI-CDRGTGKC 129
              C  G  C   +G     P        + CP   FG DC   C CQ+G  CD  +GKC
Sbjct: 712 ---CHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKC 768



 Score = 40.8 bits (94), Expect = 7e-04
 Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 26/130 (20%)

Query: 20  WSNNYAVD-CPQHCDSSECKSSPRCKR-----TVLDDCGC--------CRV-CAAGR-GE 63
           WS ++  + CP       C+    C+      ++   C C        C V CAAG  G 
Sbjct: 385 WSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP 444

Query: 64  TCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEF---GICKDCPYGTFGMDCRETCNCQSG 120
            C    S      C  G  C P +G     E +        CP GT+G++C E+C C +G
Sbjct: 445 NCSSICS------CNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498

Query: 121 -ICDRGTGKC 129
             C    G C
Sbjct: 499 AACSPIDGSC 508



 Score = 40.4 bits (93), Expect = 9e-04
 Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 18/127 (14%)

Query: 21  SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTV-SGMDGMKCGP 79
           S  + ++C + C    C +   C  + +D  G C       G+TC      G  G+ C  
Sbjct: 482 SGTWGLNCNESCT---CANGAAC--SPID--GSCSCTPGWLGDTCELPCPDGTFGLNCSE 534

Query: 80  GLRCQPSNGEDPFGEEF-------GICKD--CPYGTFGMDCRETCNCQS-GICDRGTGKC 129
              C  ++G DP            GI  D  CP G +G +C  +C+C++ G C    G C
Sbjct: 535 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC 594

Query: 130 LKFPFFQ 136
              P F+
Sbjct: 595 ECAPGFR 601



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 36/118 (30%), Positives = 44/118 (37%), Gaps = 13/118 (11%)

Query: 25  AVDCPQHCDSSECKSSPRCKR--TVLDDCGCCRVCAAGRGETCYRTV-SGMDGMKCGP-- 79
           AV C        C S   C    T     G C      +G  C     SG  G+ C    
Sbjct: 434 AVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC 493

Query: 80  ----GLRCQPSNGEDPF--GEEFGICK-DCPYGTFGMDCRETCNC-QSGICDRGTGKC 129
               G  C P +G      G     C+  CP GTFG++C E C+C  +  CD  TG C
Sbjct: 494 TCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHC 551



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 20/89 (22%)

Query: 50  DCGCCRVCAAGRGETCYRTVSGMDGMKCG-PGLRCQPSNGEDPFGEEFGICKDCPYGTFG 108
           DCG  RVC    G +C   +SG    + G  G  C+               + C  GTFG
Sbjct: 748 DCG--RVCQCQNGASCDH-ISGKCTCRTGFTGQHCE---------------QRCAPGTFG 789

Query: 109 MDCRETCNC-QSGICDRGTGKCLKFPFFQ 136
             C++ C C  +  CD  TG C   P F+
Sbjct: 790 YGCQQLCECMNNSTCDHVTGTCYCSPGFK 818



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 36/129 (27%), Positives = 45/129 (34%), Gaps = 28/129 (21%)

Query: 20  WSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVS-GMDGMKCG 78
           W  N +V C        C++   C      + G C      RG  C R    G  G  C 
Sbjct: 571 WGPNCSVSC-------SCENGGSCS----PEDGSCECAPGFRGPLCQRICPPGFYGHGCA 619

Query: 79  -PGLRCQPSNGEDPFGEEFGICKD------------CPYGTFGMDCRETCNC-QSGICDR 124
            P   C  S+   P     GIC+             C  G FG DC + C+C  +G C  
Sbjct: 620 QPCPLCVHSSR--PCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSP 677

Query: 125 GTGKCLKFP 133
             G C  FP
Sbjct: 678 IDGSCQCFP 686



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 13/31 (41%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 100 KDCPYGTFGMDCRETCNCQS-GICDRGTGKC 129
           ++CP+G+FG  C + C+C + G C   TG C
Sbjct: 303 EECPFGSFGFQCSQHCDCHNGGQCSPTTGAC 333



 Score = 31.6 bits (70), Expect = 0.40
 Identities = 31/120 (25%), Positives = 42/120 (35%), Gaps = 21/120 (17%)

Query: 24  YAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVS-GMDGMKCGP--- 79
           +  +C Q C    C    +C        G C   A   G+ C      G  G +C     
Sbjct: 267 FGQNCSQDCP---CHHGGQCDHVT----GQCHCTAGYMGDRCQEECPFGSFGFQCSQHCD 319

Query: 80  ---GLRCQPSNG--EDPFGEEFGICKD--CPYGTFGMDCRETCNCQSG---ICDRGTGKC 129
              G +C P+ G  E   G +   C++  CP G  G  C   C C +     C   TG C
Sbjct: 320 CHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGAC 379


>gi|10834982 insulin-like growth factor binding protein 5 [Homo
          sapiens]
          Length = 272

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 10/91 (10%)

Query: 4  VLLLTTLLVPAHLVAAWSNNYAVDCPQHCDS---SECKSSPR-CKRTVLDDCGCCRVCAA 59
          +L    LL+ A+   A S    V C + CD    S C  SP  C+      CGCC  CA 
Sbjct: 3  LLTAVLLLLAAYAGPAQSLGSFVHC-EPCDEKALSMCPPSPLGCELVKEPGCGCCMTCAL 61

Query: 60 GRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90
            G++C     G+   +C  GLRC P   E+
Sbjct: 62 AEGQSC-----GVYTERCAQGLRCLPRQDEE 87


>gi|4503123 connective tissue growth factor [Homo sapiens]
          Length = 349

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 24/107 (22%)

Query: 29  PQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGP--GLRCQPS 86
           P  C        P     VLD CGCCRVCA   GE C       +   C P  GL C   
Sbjct: 32  PCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELC------TERDPCDPHKGLFCDFG 85

Query: 87  NGEDPFGEEFGIC--KD---CPYG--------TFGMDCRETCNCQSG 120
           +   P   + G+C  KD   C +G        +F   C+  C C  G
Sbjct: 86  S---PANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDG 129


>gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like
           domains 1 [Homo sapiens]
          Length = 1138

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 40/125 (32%), Positives = 51/125 (40%), Gaps = 29/125 (23%)

Query: 20  WSNNYAVDCPQ-------HCDSSECKSSPRCKRTVLDDCGCCRVCAAGR-GETCYRTVSG 71
           W      +CP        H    EC   P    T      C + C  GR G++C     G
Sbjct: 220 WGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGT-----RCEQACREGRFGQSCQEQCPG 274

Query: 72  MDGMKCGPGLR-CQPSNGEDPFGEEFGI------CKD-CPYGTFGMDCRETCNCQS-GIC 122
           + G +   GL  C P    DP+G   G       C++ C  G FG DCR  C CQ+ G C
Sbjct: 275 ISGCR---GLTFCLP----DPYGCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTC 327

Query: 123 DRGTG 127
           DR +G
Sbjct: 328 DRFSG 332


>gi|62243068 insulin-like growth factor binding protein 3 isoform b
           precursor [Homo sapiens]
          Length = 291

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 10/63 (15%)

Query: 32  CDS---SECKSSPR-CKRTVLDD-CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS 86
           CD+   ++C   P  C   V +  CGCC  CA   G+ C     G+   +CG GLRCQPS
Sbjct: 43  CDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPC-----GIYTERCGSGLRCQPS 97

Query: 87  NGE 89
             E
Sbjct: 98  PDE 100


>gi|62243248 insulin-like growth factor binding protein 3 isoform a
           precursor [Homo sapiens]
          Length = 297

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 10/63 (15%)

Query: 32  CDS---SECKSSPR-CKRTVLDD-CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS 86
           CD+   ++C   P  C   V +  CGCC  CA   G+ C     G+   +CG GLRCQPS
Sbjct: 43  CDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPC-----GIYTERCGSGLRCQPS 97

Query: 87  NGE 89
             E
Sbjct: 98  PDE 100


>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
           [Homo sapiens]
          Length = 250

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 35/107 (32%), Positives = 39/107 (36%), Gaps = 20/107 (18%)

Query: 28  CPQHCDSSECKSSPRCKR---TVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQ 84
           CP  C        PRC      VLD CGCCRVCA   GE C      +       GL CQ
Sbjct: 26  CPTPCTCPW--PPPRCPLGVPLVLDGCGCCRVCARRLGEPC----DQLHVCDASQGLVCQ 79

Query: 85  PSNGEDPFGEEFGICKD---CPYG--------TFGMDCRETCNCQSG 120
           P  G    G    + +D   C           TF   C   C C+ G
Sbjct: 80  PGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDG 126


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 31/116 (26%)

Query: 28   CPQHCDSSECKSSP---RCKRTV-----LDDCGCCRVCAAGRGETCYRTVSGMDGMKCGP 79
            C  H     CK+     RC R        D CG CR CA G            +G +C P
Sbjct: 2033 CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACG---------PAAEGSECHP 2083

Query: 80   G---LRCQPSNGEDPFGEEFGICKDCPYGTFGMD---CRETCNCQSGICDRGTGKC 129
                  C+P       G +   C++C  G +G+    CR  C C  G CD  TG+C
Sbjct: 2084 QSGQCHCRPGT----MGPQ---CRECAPGYWGLPEQGCRR-CQCPGGRCDPHTGRC 2131



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 16/105 (15%)

Query: 39   SSPRCKRTVLDDCGCCRVCAAGRGETC-------YRTVSGMDGMKCGPGLRCQPSNGEDP 91
            +SP  +  +  +   C   A+ RG++C       YR V G+   +C P   CQ     D 
Sbjct: 1816 ASPAGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP---CQCHGHSDR 1872

Query: 92   FGEEFGICKDCPYGTFGMDCRETCNCQSGIC---DRGTGKCLKFP 133
                 G+C DC + T G  C     CQ+G     D  +  C+  P
Sbjct: 1873 CLPGSGVCVDCQHNTEGAHCE---RCQAGFVSSRDDPSAPCVSCP 1914



 Score = 33.9 bits (76), Expect = 0.081
 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 8/56 (14%)

Query: 80   GLRCQPSNGEDP-----FGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCL 130
            G  C+P  G+ P      G +   C  C  G +G      C+C + +CD  TG+C+
Sbjct: 1447 GPTCEPFGGQCPCHAHVIGRD---CSRCATGYWGFPNCRPCDCGARLCDELTGQCI 1499



 Score = 30.4 bits (67), Expect = 0.90
 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 24/63 (38%)

Query: 97  GICKDCPYGTFGMDCR--------------------ETCNCQS----GICDRGTGKCLKF 132
           G+C DC + T G++C                       CNC+S    G C+  TG+C   
Sbjct: 391 GVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCR 450

Query: 133 PFF 135
           P F
Sbjct: 451 PNF 453



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 25/94 (26%)

Query: 54  CRVCAAGRGETCYRTVSGMDGM---------KCGPGLR--------CQPSNGE-----DP 91
           C   A   G +C R   G  G+         +C   LR        CQP  G+       
Sbjct: 744 CMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHV 803

Query: 92  FGEEFGICKDCPYGTFGMDCRETCNCQSGICDRG 125
            G+    CKD   G FG+D  +   C+S  CD G
Sbjct: 804 CGQACASCKD---GFFGLDQADYFGCRSCRCDIG 834



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 24/98 (24%), Positives = 32/98 (32%), Gaps = 18/98 (18%)

Query: 49  DDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFG 108
           D+ G C       G  C R   G  G        C P    D      G+C+ C  G  G
Sbjct: 600 DEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCR-CRPGYTG 658

Query: 109 MDCRE------------TCNCQS-----GICDRGTGKC 129
             C+E             C+C +       CD  +G+C
Sbjct: 659 TACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQC 696


>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
           sapiens]
          Length = 278

 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 8/72 (11%)

Query: 32  CDSSECKSSPRCKR---TVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRC-QPSN 87
           C    C +   C     + LD+CGCC  C    G +C     G  G +CGPGL C   + 
Sbjct: 41  CRPEGCPAPAPCPAPGISALDECGCCARCLGAEGASC----GGRAGGRCGPGLVCASQAA 96

Query: 88  GEDPFGEEFGIC 99
           G  P G    +C
Sbjct: 97  GAAPEGTGLCVC 108


>gi|61743978 stabilin 1 precursor [Homo sapiens]
          Length = 2570

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 22/104 (21%)

Query: 42  RCKRTVLDDCGC-------CRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGE 94
           +C++ V+    C       C  C  G    C    + +DGM       CQ         E
Sbjct: 90  KCRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQ---------E 140

Query: 95  EF--GICKDCPY-GTFGMDCRETCNCQSGICD---RGTGKCLKF 132
            F    C++C     FG DC+  C+C  G+C+   RG G CL F
Sbjct: 141 NFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCF 184



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 14/95 (14%)

Query: 44   KRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQP---SNGEDPFGEEFG--I 98
            K+  + DC     C    G  C     G+ G+  G G +CQ     +GE    E F    
Sbjct: 1313 KKIQVPDC-----CPGFFGTLCEPCPGGLGGVCSGHG-QCQDRFLGSGECHCHEGFHGTA 1366

Query: 99   CKDCPYGTFGMDCRETCNCQSGICD---RGTGKCL 130
            C+ C  G +G +C   C+C  G+C    +G G C+
Sbjct: 1367 CEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCV 1401



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 15/93 (16%)

Query: 43  CKRTVLDDCGCCR--------VCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGE 94
           C +T+++  GCC+         C  G    CY   +  DG++      C P    D  G 
Sbjct: 711 CNQTIMEQ-GCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFP----DYKGI 765

Query: 95  EFGICKDCPYGTFGMDCRETCNCQSGICDRGTG 127
              IC +      G  C+E C C  G+CD   G
Sbjct: 766 ACHICSNP--NKHGEQCQEDCGCVHGLCDNRPG 796



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 23/75 (30%), Positives = 27/75 (36%), Gaps = 9/75 (12%)

Query: 54   CRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRE 113
            C+ C  G    C      MDGM       C+        G     C+ C  G FG  C +
Sbjct: 1968 CQACPGGPSSPCSDRGVCMDGMSGSGQCLCRS-------GFAGTACELCAPGAFGPHC-Q 2019

Query: 114  TCNCQ-SGICDRGTG 127
             C C   G CD G G
Sbjct: 2020 ACRCTVHGRCDEGLG 2034


>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
           sapiens]
          Length = 870

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 24/126 (19%)

Query: 24  YAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG-RGETCYRT-VSGMDGMKCGPGL 81
           Y + C + C   +CK    C  TV +  G C  C  G  G  C +   +G  G  C    
Sbjct: 278 YGLGCRRRC--GQCKGQQPC--TVAE--GRCLTCEPGWNGTKCDQPCATGFYGEGCSH-- 329

Query: 82  RCQPSNGEDPFGEEFGICK-------------DCPYGTFGMDCRETC-NCQSGICDRGTG 127
           RC P           G C               C  GT+G DC   C +C SG CD  +G
Sbjct: 330 RCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSG 389

Query: 128 KCLKFP 133
           +CL  P
Sbjct: 390 RCLCSP 395



 Score = 40.4 bits (93), Expect = 9e-04
 Identities = 31/126 (24%), Positives = 44/126 (34%), Gaps = 23/126 (18%)

Query: 23  NYAVDCPQHCDSSECKSSPRCK-----RTVLDDCGC--------CRVCAAGRGETCY--- 66
           N    CP+     +CK    C        V   C C        C      +  TC+   
Sbjct: 108 NCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRS 167

Query: 67  ---RTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICD 123
              R   G  G +C     C  ++  DP   + G C  C  G +G  C   C C S  C+
Sbjct: 168 GACRCEPGWWGAQCASACYCSATSRCDP---QTGACL-CHAGWWGRSCNNQCACNSSPCE 223

Query: 124 RGTGKC 129
           + +G+C
Sbjct: 224 QQSGRC 229



 Score = 34.7 bits (78), Expect = 0.048
 Identities = 33/105 (31%), Positives = 44/105 (41%), Gaps = 24/105 (22%)

Query: 32  CDSSECKS-SPRCK-RTVLDDCGCCRVCAAGRGETCYRTVSGMDGM-KCGPGLRCQPSNG 88
           C+SS C+  S RC+ R       C R C   RG  C+     +DG   C PG R +    
Sbjct: 217 CNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHP----VDGTCACEPGYRGK---- 267

Query: 89  EDPFGEEFGICKD-CPYGTFGMDCRETCNCQSG--ICDRGTGKCL 130
                     C++ CP G +G+ CR  C    G   C    G+CL
Sbjct: 268 ---------YCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCL 303



 Score = 31.6 bits (70), Expect = 0.40
 Identities = 29/104 (27%), Positives = 38/104 (36%), Gaps = 19/104 (18%)

Query: 35  SECKSSPRCKRTVLDD--CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPF 92
           ++C S+  C  T   D   G C +C AG             G  C     C  S    P 
Sbjct: 179 AQCASACYCSATSRCDPQTGAC-LCHAGWW-----------GRSCNNQCACNSS----PC 222

Query: 93  GEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQ 136
            ++ G C+ C   TFG  C   C C  G C    G C   P ++
Sbjct: 223 EQQSGRCQ-CRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYR 265


>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
           sapiens]
          Length = 865

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 24/126 (19%)

Query: 24  YAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG-RGETCYRT-VSGMDGMKCGPGL 81
           Y + C + C   +CK    C  TV +  G C  C  G  G  C +   +G  G  C    
Sbjct: 278 YGLGCRRRC--GQCKGQQPC--TVAE--GRCLTCEPGWNGTKCDQPCATGFYGEGCSH-- 329

Query: 82  RCQPSNGEDPFGEEFGICK-------------DCPYGTFGMDCRETC-NCQSGICDRGTG 127
           RC P           G C               C  GT+G DC   C +C SG CD  +G
Sbjct: 330 RCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSG 389

Query: 128 KCLKFP 133
           +CL  P
Sbjct: 390 RCLCSP 395



 Score = 40.4 bits (93), Expect = 9e-04
 Identities = 31/126 (24%), Positives = 44/126 (34%), Gaps = 23/126 (18%)

Query: 23  NYAVDCPQHCDSSECKSSPRCK-----RTVLDDCGC--------CRVCAAGRGETCY--- 66
           N    CP+     +CK    C        V   C C        C      +  TC+   
Sbjct: 108 NCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRS 167

Query: 67  ---RTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICD 123
              R   G  G +C     C  ++  DP   + G C  C  G +G  C   C C S  C+
Sbjct: 168 GACRCEPGWWGAQCASACYCSATSRCDP---QTGACL-CHAGWWGRSCNNQCACNSSPCE 223

Query: 124 RGTGKC 129
           + +G+C
Sbjct: 224 QQSGRC 229



 Score = 34.7 bits (78), Expect = 0.048
 Identities = 33/105 (31%), Positives = 44/105 (41%), Gaps = 24/105 (22%)

Query: 32  CDSSECKS-SPRCK-RTVLDDCGCCRVCAAGRGETCYRTVSGMDGM-KCGPGLRCQPSNG 88
           C+SS C+  S RC+ R       C R C   RG  C+     +DG   C PG R +    
Sbjct: 217 CNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHP----VDGTCACEPGYRGK---- 267

Query: 89  EDPFGEEFGICKD-CPYGTFGMDCRETCNCQSG--ICDRGTGKCL 130
                     C++ CP G +G+ CR  C    G   C    G+CL
Sbjct: 268 ---------YCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCL 303



 Score = 31.6 bits (70), Expect = 0.40
 Identities = 29/104 (27%), Positives = 38/104 (36%), Gaps = 19/104 (18%)

Query: 35  SECKSSPRCKRTVLDD--CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPF 92
           ++C S+  C  T   D   G C +C AG             G  C     C  S    P 
Sbjct: 179 AQCASACYCSATSRCDPQTGAC-LCHAGWW-----------GRSCNNQCACNSS----PC 222

Query: 93  GEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQ 136
            ++ G C+ C   TFG  C   C C  G C    G C   P ++
Sbjct: 223 EQQSGRCQ-CRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYR 265


>gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo
           sapiens]
          Length = 1124

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 30/161 (18%)

Query: 15  HLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDG 74
           HL  A  NN       H D+ EC   P       +    C +   GR  TC    SG +G
Sbjct: 222 HLCTACMNNGVC----HEDTGECICPPGFMGRTCEKA--CELHTFGR--TCKERCSGQEG 273

Query: 75  MKCGPGLRCQPSNGEDPFGEEFGI------CKD-CPYGTFGMDCRETCNCQSG-ICDRGT 126
             C   + C P    DP+G           C + C  G +G DC+  C+C +G +CDR  
Sbjct: 274 --CKSYVFCLP----DPYGCSCATGWKGLQCNEACHPGFYGPDCKLRCSCNNGEMCDRFQ 327

Query: 127 GKCLKFPFFQ------YSVTKSSNRFVSLTEH-DMASGDGN 160
           G CL  P +Q        + + + + V L +H ++ SG  N
Sbjct: 328 G-CLCSPGWQGLQCEREGIPRMTPKIVDLPDHIEVNSGKFN 367


>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
           [Homo sapiens]
          Length = 328

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%)

Query: 51  CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90
           CGCC VCA   GE C     G+   +CG GLRC P  G +
Sbjct: 87  CGCCSVCARLEGEAC-----GVYTPRCGQGLRCYPHPGSE 121


>gi|61743980 stabilin 2 precursor [Homo sapiens]
          Length = 2551

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 18/94 (19%)

Query: 41   PRCKRTVLDDCGC-------CRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFG 93
            P+C RTV+    C       C+ C       C+     +DG+  G G+ C+        G
Sbjct: 1325 PKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVN-GTGV-CE-------CG 1375

Query: 94   EEFG--ICKDCPYGTFGMDCRETCNCQSGICDRG 125
            E F    C+ C  G +G+ C + C+C  G C++G
Sbjct: 1376 EGFSGTACETCTEGKYGIHCDQACSCVHGRCNQG 1409



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 23/72 (31%), Positives = 27/72 (37%), Gaps = 6/72 (8%)

Query: 54  CRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRE 113
           C  C  G G  C    S  +GM+      CQ   G    G     C D     FG  C  
Sbjct: 109 CIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFG----GTACETCADD--NLFGPSCSS 162

Query: 114 TCNCQSGICDRG 125
            CNC  G+C+ G
Sbjct: 163 VCNCVHGVCNSG 174



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 26/91 (28%), Positives = 32/91 (35%), Gaps = 9/91 (9%)

Query: 37  CKSSPRCKRTV----LDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPF 92
           C S   C   V    LD  G C   +A  G  C + +     + C    RC PS  ++  
Sbjct: 160 CSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENK 219

Query: 93  GEEFGICKDCP-YGTFGMDCRETCNCQSGIC 122
            E    CK  P Y   G  C     C   IC
Sbjct: 220 LE----CKCLPNYRGDGKYCDPINPCLRKIC 246



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 26/98 (26%), Positives = 37/98 (37%), Gaps = 20/98 (20%)

Query: 52  GCCRVC-AAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFG-----ICKDCPYG 105
           GC R C A  +   C +   G D  +C PG    P +G     +  G     IC++   G
Sbjct: 714 GCARYCNATVKIPKCCKGFYGPDCNQC-PGGFSNPCSGNGQCADSLGGNGTCICEEGFQG 772

Query: 106 T----------FGMDCRETCNCQSGICDR---GTGKCL 130
           +          +G  C + C C  G C+      G CL
Sbjct: 773 SQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACL 810



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 24/82 (29%), Positives = 30/82 (36%), Gaps = 14/82 (17%)

Query: 54   CRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS-NGEDPFGEEFGICKDCPYGTFGMDCR 112
            C+ C  G    C      +D        +C    NG          C+ C  G FG DC 
Sbjct: 1959 CQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGT--------ACEMCWPGRFGPDCL 2010

Query: 113  ETCNCQS-GICD---RGTGKCL 130
              C C   G CD    G+G+CL
Sbjct: 2011 -PCGCSDHGQCDDGITGSGQCL 2031


>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 39/166 (23%), Positives = 52/166 (31%), Gaps = 53/166 (31%)

Query: 22  NNYAVDCPQHCDSSECKS--------SPRCKRTVLDDCGCCRVCAAGRGETCYR------ 67
           + Y V C ++     C+         S R        C C     A   E+CYR      
Sbjct: 95  SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVR 154

Query: 68  -----TVSGMDGMKCGPGL------------RCQPSNGEDP------FGEEFGICKDCPY 104
                  +G +  +C PG             +C  S   DP        E  G C++C  
Sbjct: 155 CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLR 214

Query: 105 GTFGMDCRE----------------TCNCQSGICDRGTGKCLKFPF 134
            T G  C                   CNC  G CD  TG+CL+  F
Sbjct: 215 NTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGF 260


>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 1823

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 39/166 (23%), Positives = 52/166 (31%), Gaps = 53/166 (31%)

Query: 22  NNYAVDCPQHCDSSECKS--------SPRCKRTVLDDCGCCRVCAAGRGETCYR------ 67
           + Y V C ++     C+         S R        C C     A   E+CYR      
Sbjct: 95  SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVR 154

Query: 68  -----TVSGMDGMKCGPGL------------RCQPSNGEDP------FGEEFGICKDCPY 104
                  +G +  +C PG             +C  S   DP        E  G C++C  
Sbjct: 155 CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLR 214

Query: 105 GTFGMDCRE----------------TCNCQSGICDRGTGKCLKFPF 134
            T G  C                   CNC  G CD  TG+CL+  F
Sbjct: 215 NTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGF 260


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,594,150
Number of Sequences: 37866
Number of extensions: 441447
Number of successful extensions: 1355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 99
Number of HSP's that attempted gapping in prelim test: 997
Number of HSP's gapped (non-prelim): 354
length of query: 184
length of database: 18,247,518
effective HSP length: 96
effective length of query: 88
effective length of database: 14,612,382
effective search space: 1285889616
effective search space used: 1285889616
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.