Search of human proteins with 5729810

Search of human proteins with 5729810

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729810 emopamil binding protein (sterol isomerase) [Homo
sapiens]
         (230 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5729810 emopamil binding protein (sterol isomerase) [Homo sap...   489   e-138
gi|14211873 emopamil binding related protein, delta8-delta7 ster...    90   1e-18
gi|41281564 WD repeat domain 37 [Homo sapiens]                         30   1.7  
gi|21536466 AXL receptor tyrosine kinase isoform 1 [Homo sapiens]      28   5.0  
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]            28   6.6  
gi|63259329 transmembrane protein 184B [Homo sapiens]                  28   6.6  

>gi|5729810 emopamil binding protein (sterol isomerase) [Homo
           sapiens]
          Length = 230

 Score =  489 bits (1258), Expect = e-138
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MTTNAGPLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGT 60
           MTTNAGPLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGT
Sbjct: 1   MTTNAGPLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGT 60

Query: 61  WRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVC 120
           WRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVC
Sbjct: 61  WRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVC 120

Query: 121 METITACLWGPLSLWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELG 180
           METITACLWGPLSLWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELG
Sbjct: 121 METITACLWGPLSLWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELG 180

Query: 181 HPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTHAQSTLDAKATKAKSKKN 230
           HPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTHAQSTLDAKATKAKSKKN
Sbjct: 181 HPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTHAQSTLDAKATKAKSKKN 230


>gi|14211873 emopamil binding related protein, delta8-delta7 sterol
           isomerase [Homo sapiens]
          Length = 206

 Score = 90.1 bits (222), Expect = 1e-18
 Identities = 54/172 (31%), Positives = 91/172 (52%), Gaps = 10/172 (5%)

Query: 41  VLVVTTWLLSGRAAVVPLGTWR----RLSLCWFAVCGFIHLVIEGWFVLYYEDLLGDQA- 95
           +L+    L +G A  + LG  +    R +L W      +H  +EG FV  Y  L+G+ A 
Sbjct: 15  LLLCAALLAAGCALGLRLGRGQGAADRGALIWLCYDALVHFALEGPFV--YLSLVGNVAN 72

Query: 96  ---FLSQLWKEYAKGDSRYILGDNFTVCMETITACLWGPLSLWVVIAFLRQHPLRFILQL 152
               ++ LWKEY K D+R++  D   V +E +T  L G L+L+++ A +++   R  LQ+
Sbjct: 73  SDGLIASLWKEYGKADARWVYFDPTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQI 132

Query: 153 VVSVGQIYGDVLYFLTEHRDGFQHGELGHPLYFWFYFVFMNALWLVLPGVLV 204
            + V ++YG  + FL E      +    + LY W Y  F N +W+++PG+L+
Sbjct: 133 TLCVCELYGCWMTFLPEWLTRSPNLNTSNWLYCWLYLFFFNGVWVLIPGLLL 184


>gi|41281564 WD repeat domain 37 [Homo sapiens]
          Length = 494

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)

Query: 18  LDNFVPNDRPTWHI-LAGLFSVTGVLVVTTWLLSGRAAVVPLGTWRR 63
           LD  V +D PT  + L  L S  GV++ + WL+ G+ AV    +W R
Sbjct: 259 LDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVT--ASWDR 303


>gi|21536466 AXL receptor tyrosine kinase isoform 1 [Homo sapiens]
          Length = 894

 Score = 28.5 bits (62), Expect = 5.0
 Identities = 40/161 (24%), Positives = 58/161 (36%), Gaps = 32/161 (19%)

Query: 6   GPLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGTWRRLS 65
           G LHP+ P H+R+         +W               T WL       VPLG    +S
Sbjct: 297 GSLHPHTPYHIRVACTSSQGPSSW---------------THWLPVETPEGVPLGPPENIS 341

Query: 66  LCWFAVCGFIHL---------VIEGWFVLYY----EDLLGDQAFLSQLWKEYAKGDSRYI 112
                   F+H           + G+ + Y      ++L D     ++  E  +GD    
Sbjct: 342 ATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLEL-QGDGSV- 399

Query: 113 LGDNFTVCMETITACLWGPLSLWVVIAFLRQHPLRFILQLV 153
              N TVC+   TA   GP SL V +   R    + + QLV
Sbjct: 400 --SNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLV 438


>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
          Length = 4588

 Score = 28.1 bits (61), Expect = 6.6
 Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 144  HPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELG 180
            H +R++  +    G+  G+V Y+L EH + FQ G LG
Sbjct: 2098 HVIRYVTAVDRDSGR-NGEVHYYLKEHHEHFQIGPLG 2133


>gi|63259329 transmembrane protein 184B [Homo sapiens]
          Length = 407

 Score = 28.1 bits (61), Expect = 6.6
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 16/98 (16%)

Query: 77  LVIEGWFVLYYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVCMETITACLWGPLSLWV 136
           LVI  +  L YE L G+ + +S++  +  +    Y             T CLWG      
Sbjct: 121 LVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCMYG------------TCCLWGKTYSIG 168

Query: 137 VIAFLRQHPLRF-ILQLVVSVGQIYGDVLYFLTEHRDG 173
            + F +Q  L+F +++ +++V  +   VL    ++RDG
Sbjct: 169 FLRFCKQATLQFCVVKPLMAVSTV---VLQAFGKYRDG 203


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.143    0.491 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,973,379
Number of Sequences: 37866
Number of extensions: 368995
Number of successful extensions: 833
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 828
Number of HSP's gapped (non-prelim): 6
length of query: 230
length of database: 18,247,518
effective HSP length: 99
effective length of query: 131
effective length of database: 14,498,784
effective search space: 1899340704
effective search space used: 1899340704
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.