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Search of human proteins with 56549125
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
(866 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56549125 dynamin 2 isoform 4 [Homo sapiens] 1717 0.0
gi|56549123 dynamin 2 isoform 2 [Homo sapiens] 1711 0.0
gi|56549119 dynamin 2 isoform 3 [Homo sapiens] 1700 0.0
gi|56549121 dynamin 2 isoform 1 [Homo sapiens] 1694 0.0
gi|209915561 dynamin 3 isoform b [Homo sapiens] 1377 0.0
gi|42544243 dynamin 3 isoform a [Homo sapiens] 1373 0.0
gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 1352 0.0
gi|56549117 dynamin 1 isoform 2 [Homo sapiens] 1343 0.0
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens] 499 e-141
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens] 452 e-127
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens] 452 e-127
gi|222136619 myxovirus resistance protein 1 [Homo sapiens] 239 1e-62
gi|222136617 myxovirus resistance protein 1 [Homo sapiens] 239 1e-62
gi|11342664 myxovirus resistance protein 2 [Homo sapiens] 223 6e-58
gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens] 122 2e-27
gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens] 122 2e-27
gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens] 122 2e-27
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 114 4e-25
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 114 4e-25
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 114 4e-25
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 114 4e-25
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 114 4e-25
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 114 4e-25
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 114 4e-25
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] 114 4e-25
gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens] 91 5e-18
gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo ... 88 4e-17
gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo ... 88 4e-17
gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo ... 84 7e-16
gi|7706501 WW domain binding protein 11 [Homo sapiens] 59 3e-08
>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
Length = 866
Score = 1717 bits (4447), Expect = 0.0
Identities = 866/866 (100%), Positives = 866/866 (100%)
Query: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
Sbjct: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
Query: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE
Sbjct: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
Query: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660
LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV
Sbjct: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660
Query: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720
AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR
Sbjct: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720
Query: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV 780
MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV
Sbjct: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV 780
Query: 781 RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP 840
RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP
Sbjct: 781 RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP 840
Query: 841 GVPSRRPPAAPSRPTIIRPAEPSLLD 866
GVPSRRPPAAPSRPTIIRPAEPSLLD
Sbjct: 841 GVPSRRPPAAPSRPTIIRPAEPSLLD 866
>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
Length = 870
Score = 1711 bits (4432), Expect = 0.0
Identities = 866/870 (99%), Positives = 866/870 (99%), Gaps = 4/870 (0%)
Query: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
Sbjct: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536
IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ VIRRGWLTINNISLMKGGSKE
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540
Query: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596
YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600
Query: 597 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 656
RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 660
Query: 657 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 716
DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD
Sbjct: 661 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 720
Query: 717 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR 776
DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR
Sbjct: 721 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR 780
Query: 777 PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP 836
PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP
Sbjct: 781 PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP 840
Query: 837 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD
Sbjct: 841 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 870
>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
Length = 866
Score = 1700 bits (4402), Expect = 0.0
Identities = 853/866 (98%), Positives = 859/866 (99%)
Query: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
Sbjct: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPD+AFEAIVKKQ+VKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420
Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
KEP LKCVDLV+ EL +++C KLSSYPRLREETERIVTTYIREREGRTKDQILLLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
Query: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE
Sbjct: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
Query: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660
LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV
Sbjct: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660
Query: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720
AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR
Sbjct: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720
Query: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV 780
MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV
Sbjct: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAV 780
Query: 781 RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP 840
RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP
Sbjct: 781 RGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPP 840
Query: 841 GVPSRRPPAAPSRPTIIRPAEPSLLD 866
GVPSRRPPAAPSRPTIIRPAEPSLLD
Sbjct: 841 GVPSRRPPAAPSRPTIIRPAEPSLLD 866
>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
Length = 870
Score = 1694 bits (4387), Expect = 0.0
Identities = 853/870 (98%), Positives = 859/870 (98%), Gaps = 4/870 (0%)
Query: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI
Sbjct: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPD+AFEAIVKKQ+VKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420
Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
KEP LKCVDLV+ EL +++C KLSSYPRLREETERIVTTYIREREGRTKDQILLLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536
IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ VIRRGWLTINNISLMKGGSKE
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540
Query: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596
YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600
Query: 597 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 656
RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLV 660
Query: 657 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 716
DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD
Sbjct: 661 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 720
Query: 717 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR 776
DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR
Sbjct: 721 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGR 780
Query: 777 PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP 836
PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP
Sbjct: 781 PPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP 840
Query: 837 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD
Sbjct: 841 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 870
>gi|209915561 dynamin 3 isoform b [Homo sapiens]
Length = 859
Score = 1377 bits (3565), Expect = 0.0
Identities = 695/870 (79%), Positives = 769/870 (88%), Gaps = 15/870 (1%)
Query: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP R+KL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
+INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
K PSLK VDLV+ EL +KKC +KL+++PRL EETERIV +IREREG+TKDQ+LLLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
I+ SYINTNHEDFIGFANAQQRS+Q++KK + NQVIR+GWLTI+NI +MKGGSK YWFV
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
Query: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
LTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD R +E
Sbjct: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
Query: 601 LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV 660
LACDSQEDVDSWKAS LRAGVYP+K AEN++ Q FSMDPQLERQVETIRNLVDSY+
Sbjct: 601 LACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYM 660
Query: 661 AIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLR 720
+IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD+MLR
Sbjct: 661 SIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLR 720
Query: 721 MYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHPPGRP 777
MY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q + SPT QRRP S P RP
Sbjct: 721 MYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-PLARP 779
Query: 778 PAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPVRIPP 836
+ RGP P IP P APP+P RPGP F ++SD F APPQ+PSRP R
Sbjct: 780 TSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTR--- 830
Query: 837 GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 831 -APPSVPSRRPPPSPTRPTIIRPLESSLLD 859
>gi|42544243 dynamin 3 isoform a [Homo sapiens]
Length = 863
Score = 1373 bits (3554), Expect = 0.0
Identities = 695/874 (79%), Positives = 771/874 (88%), Gaps = 19/874 (2%)
Query: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP R+KL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
+INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
K PSLK VDLV+ EL +KKC +KL+++PRL EETERIV +IREREG+TKDQ+LLLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
I+ SYINTNHEDFIGFANAQQRS+Q++KK + NQVIR+GWLTI+NI +MKGGSK YWFV
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
Query: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
LTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD R +E
Sbjct: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
Query: 601 LACDSQEDVDSWKASFLRAGVYPEK----DQAENEDGAQENTFSMDPQLERQVETIRNLV 656
LACDSQEDVDSWKAS LRAGVYP+K ++AEN++ Q FSMDPQLERQVETIRNLV
Sbjct: 601 LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV 660
Query: 657 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 716
DSY++IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD
Sbjct: 661 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 720
Query: 717 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHP 773
+MLRMY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q + SPT QRRP S P
Sbjct: 721 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-P 779
Query: 774 PGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPV 832
RP + RGP P IP P APP+P RPGP F ++SD F APPQ+PSRP
Sbjct: 780 LARPTSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPT 833
Query: 833 RIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
R PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 834 R----APPSVPSRRPPPSPTRPTIIRPLESSLLD 863
>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
Length = 864
Score = 1352 bits (3500), Expect = 0.0
Identities = 683/877 (77%), Positives = 769/877 (87%), Gaps = 35/877 (3%)
Query: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNRGME+LIPLVN+LQDAFS+IGQ+ LDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
SGIVTRRPL+LQL+ + TE+AEFLHCK KKFTDF+EVR EIEAETDRVTGTNKGISPVPI
Sbjct: 61 SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QI+DM++QF+++E+ LILAV+PAN D
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
DI+GKKDI AALAAERKFFLSHP+YRH+ADRMGTP+LQK LNQQLTNHIR++LP LR+KL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
QSQLLS+EKEVEEYKNFRPDDP RKTKALLQMVQQF VDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
RINRIFHERFPFELVKMEFDEK+LRREISYAIKNIHG+RTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
+EP LKCVD+V+SEL + +++C +KL YPRLREE ERIVTT+IREREGRTK+Q++LLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536
IE +Y+NTNHEDFIGFANAQQRS Q+NKK+ NQ VIR+GWLTINNI +MKGGSKE
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
Query: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596
YWFVLTAE+LSWYKD+EEKEKKYML +DNLK+RDVEKGFMS+KH+FA+FNTEQRNVYKD
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
Query: 597 RQIELACDSQEDVDSWKASFLRAGVYP------EKDQAENEDGAQENTFSMDPQLERQVE 650
RQ+ELAC++QE+VDSWKASFLRAGVYP EK E+G+ SMDPQLERQVE
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
Query: 651 TIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAD 710
TIRNLVDSY+AI+NK++RDLMPKTIMHLMINNTK FI ELLA LYS DQ++LMEESA+
Sbjct: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
Query: 711 QAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSAS--------SHSPT 762
QAQRRD+MLRMYHALKEAL+IIGDI+T+TVSTP+PPPVDD+WLQ S + SPT
Sbjct: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
Query: 763 PQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFP 822
PQRR + PP RP + RGP PGPP P G+A APP+PSRPG A+ D F
Sbjct: 781 PQRR--APAVPPARPGS-RGPAPGPP----PAGSALG-GAPPVPSRPG-----ASPDPFG 827
Query: 823 APPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRP 859
PPQ+PSRP R PPGVPSR A+PSRP RP
Sbjct: 828 PPPQVPSRPNR----APPGVPSRSGQASPSRPESPRP 860
>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
Length = 851
Score = 1343 bits (3475), Expect = 0.0
Identities = 673/857 (78%), Positives = 759/857 (88%), Gaps = 31/857 (3%)
Query: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNRGME+LIPLVN+LQDAFS+IGQ+ LDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
SGIVTRRPL+LQL+ + TE+AEFLHCK KKFTDF+EVR EIEAETDRVTGTNKGISPVPI
Sbjct: 61 SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QI+DM++QF+++E+ LILAV+PAN D
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
DI+GKKDI AALAAERKFFLSHP+YRH+ADRMGTP+LQK LNQQLTNHIR++LP LR+KL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
Query: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
QSQLLS+EKEVEEYKNFRPDDP RKTKALLQMVQQF VDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
Query: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
RINRIFHERFPFELVKMEFDEK+LRREISYAIKNIHG+RTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
Query: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
+EP LKCVD+V+SEL + +++C +KL YPRLREE ERIVTT+IREREGRTK+Q++LLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
Query: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQ----VIRRGWLTINNISLMKGGSKE 536
IE +Y+NTNHEDFIGFANAQQRS Q+NKK+ NQ VIR+GWLTINNI +MKGGSKE
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
Query: 537 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 596
YWFVLTAE+LSWYKD+EEKEKKYML +DNLK+RDVEKGFMS+KH+FA+FNTEQRNVYKD
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
Query: 597 RQIELACDSQEDVDSWKASFLRAGVYP------EKDQAENEDGAQENTFSMDPQLERQVE 650
RQ+ELAC++QE+VDSWKASFLRAGVYP EK E+G+ SMDPQLERQVE
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
Query: 651 TIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAD 710
TIRNLVDSY+AI+NK++RDLMPKTIMHLMINNTK FI ELLA LYS DQ++LMEESA+
Sbjct: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
Query: 711 QAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSAS--------SHSPT 762
QAQRRD+MLRMYHALKEAL+IIGDI+T+TVSTP+PPPVDD+WLQ S + SPT
Sbjct: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
Query: 763 PQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFP 822
PQRR + PP RP + RGP PGPP P G+A APP+PSRPG A+ D F
Sbjct: 781 PQRR--APAVPPARPGS-RGPAPGPP----PAGSALG-GAPPVPSRPG-----ASPDPFG 827
Query: 823 APPQIPSRPVRIPPGIP 839
PPQ+PSRP R PPG+P
Sbjct: 828 PPPQVPSRPNRAPPGVP 844
>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
Length = 736
Score = 499 bits (1285), Expect = e-141
Identities = 308/756 (40%), Positives = 445/756 (58%), Gaps = 52/756 (6%)
Query: 6 MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
ME LIP++NKLQD F+++G + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
Query: 66 RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
RRPLILQL+ E +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
Query: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS +S
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
Query: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
+ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
Query: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
G IGVVNRSQ DI KK + ++ E F Y +A+R GT +L +TLN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
Query: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
R+ LP L++++ L + + N + K+ LLQ++ +F ++ IEG+
Sbjct: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353
Query: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAF 409
++T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
Query: 410 EAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCA----EKLSSYPRLREETERIVTTYIR 465
E +VK+QI +L+EPSL+CV+LV E+ +I+ C+ ++L +P+L + +VT +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
Query: 466 EREGRTKDQILLLIDIEQSYINTNHEDF---IGFANAQQRSTQLNK-KRAIPNQVIRRGW 521
+R T + + L+ IE +YINT H DF G N + N+ R +P+ V R
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKS 533
Query: 522 LTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHV 581
+ S + S+E +AE+ + +E K + V++ N
Sbjct: 534 SKVP--SALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTGN--- 588
Query: 582 FAIFNTEQRNVYKDLRQIE-LACDSQEDVDSWKASFLRAGVYPEKDQAEN-EDGAQENTF 639
R + K + E LA + + + AS P+K A N D
Sbjct: 589 -------WRGMLKTSKAEELLAEEKSKPIPIMPAS-------PQKGHAVNLLDVPVPVAR 634
Query: 640 SMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSA 699
+ + +R E I L+ SY I+ K+I+D +PK +MH ++N+ K + EL+ LY S+
Sbjct: 635 KLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSS 694
Query: 700 DQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDI 735
L+ ES D AQRR + M AL+ A II +I
Sbjct: 695 LLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEI 730
>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
Length = 699
Score = 452 bits (1164), Expect = e-127
Identities = 251/537 (46%), Positives = 353/537 (65%), Gaps = 31/537 (5%)
Query: 6 MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
ME LIP++NKLQD F+++G + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
Query: 66 RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
RRPLILQL+ E +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
Query: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS +S
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
Query: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
+ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
Query: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
G IGVVNRSQ DI KK + ++ E F Y +A+R GT +L +TLN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
Query: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
R+ LP L++++ L + + N + K+ LLQ++ +F ++ IEG+
Sbjct: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353
Query: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAF 409
++T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
Query: 410 EAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCA----EKLSSYPRLREETERIVTTYIR 465
E +VK+QI +L+EPSL+CV+LV E+ +I+ C+ ++L +P+L + +VT +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
Query: 466 EREGRTKDQILLLIDIEQSYINTNHEDF---IGFANAQQRSTQLNK-KRAIPNQVIR 518
+R T + + L+ IE +YINT H DF G N + N+ R +P+ V R
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSR 530
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/90 (40%), Positives = 53/90 (58%)
Query: 646 ERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM 705
+R E I L+ SY I+ K+I+D +PK +MH ++N+ K + EL+ LY S+ L+
Sbjct: 604 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 663
Query: 706 EESADQAQRRDDMLRMYHALKEALNIIGDI 735
ES D AQRR + M AL+ A II +I
Sbjct: 664 TESEDMAQRRKEAADMLKALQGASQIIAEI 693
>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
Length = 710
Score = 452 bits (1164), Expect = e-127
Identities = 251/537 (46%), Positives = 353/537 (65%), Gaps = 31/537 (5%)
Query: 6 MEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
ME LIP++NKLQD F+++G + LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1 MEALIPVINKLQDVFNTVGADI-IQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
Query: 66 RRPLILQLIFSKTEH----------------AEFLHCKSKKFTDFDEVRQEIEAETDRVT 109
RRPLILQL+ E +FLH K+K +TDFDE+RQEIE ET+R++
Sbjct: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
Query: 110 GTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESS 169
G NKG+SP PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QI+++IL+FIS +S
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
Query: 170 LILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
+ILAVT AN D+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
Query: 230 GYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHI 289
G IGVVNRSQ DI KK + ++ E F Y +A+R GT +L +TLN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
Query: 290 RESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGD 349
R+ LP L++++ L + + N + K+ LLQ++ +F ++ IEG+
Sbjct: 298 RDCLPELKTRIN----VLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAK 353
Query: 350 QVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAF 409
++T EL GGARI IFHE F L ++ +I AI+N G R LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
Query: 410 EAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCA----EKLSSYPRLREETERIVTTYIR 465
E +VK+QI +L+EPSL+CV+LV E+ +I+ C+ ++L +P+L + +VT +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
Query: 466 EREGRTKDQILLLIDIEQSYINTNHEDF---IGFANAQQRSTQLNK-KRAIPNQVIR 518
+R T + + L+ IE +YINT H DF G N + N+ R +P+ V R
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSR 530
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/90 (40%), Positives = 53/90 (58%)
Query: 646 ERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLM 705
+R E I L+ SY I+ K+I+D +PK +MH ++N+ K + EL+ LY S+ L+
Sbjct: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
Query: 706 EESADQAQRRDDMLRMYHALKEALNIIGDI 735
ES D AQRR + M AL+ A II +I
Sbjct: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704
>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 239 bits (609), Expect = 1e-62
Identities = 158/435 (36%), Positives = 245/435 (56%), Gaps = 15/435 (3%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTR 66
E++ P ++ L D+ ++G L LP IAV+G QS+GKSSVLE G LPRGSGIVTR
Sbjct: 47 EKVRPCID-LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTR 104
Query: 67 RPLILQLIFSKTEHAEFLHCKSK------KFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
PL+L+L K + + K + +D EV +EI + + G GIS I
Sbjct: 105 CPLVLKL--KKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELI 162
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
L + S V +LTLIDLPGIT+V VG+QP DI Y+IK +I ++I R+ ++ L V P+N+D
Sbjct: 163 TLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVD 222
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYIGVVNRS 238
+A ++AL +A+EVDP+G RTIG++TK DL+D+GT+ + DV+ N + L++GY+ V R
Sbjct: 223 IATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRG 282
Query: 239 QKDIEGKKDIRAALAAERKFFLSHPAYRHMAD--RMGTPHLQKTLNQQLTNHIRESLPAL 296
Q++I+ + + AL E+ FF +HP +R + + + P L + L +L HI +SLP L
Sbjct: 283 QQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLL 342
Query: 297 RSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLEL 356
++++ + +E+++Y P+D K L+ V F D ++G + V ++
Sbjct: 343 ENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEEDI 401
Query: 357 SGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQ 416
R+ FH+ + K L R+I G F FE IVK+Q
Sbjct: 402 RLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQ 461
Query: 417 IVKLKEPSLKCVDLV 431
I L+EP++ + V
Sbjct: 462 IKALEEPAVDMLHTV 476
>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 239 bits (609), Expect = 1e-62
Identities = 158/435 (36%), Positives = 245/435 (56%), Gaps = 15/435 (3%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTR 66
E++ P ++ L D+ ++G L LP IAV+G QS+GKSSVLE G LPRGSGIVTR
Sbjct: 47 EKVRPCID-LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTR 104
Query: 67 RPLILQLIFSKTEHAEFLHCKSK------KFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
PL+L+L K + + K + +D EV +EI + + G GIS I
Sbjct: 105 CPLVLKL--KKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELI 162
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
L + S V +LTLIDLPGIT+V VG+QP DI Y+IK +I ++I R+ ++ L V P+N+D
Sbjct: 163 TLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVD 222
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYIGVVNRS 238
+A ++AL +A+EVDP+G RTIG++TK DL+D+GT+ + DV+ N + L++GY+ V R
Sbjct: 223 IATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRG 282
Query: 239 QKDIEGKKDIRAALAAERKFFLSHPAYRHMAD--RMGTPHLQKTLNQQLTNHIRESLPAL 296
Q++I+ + + AL E+ FF +HP +R + + + P L + L +L HI +SLP L
Sbjct: 283 QQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLL 342
Query: 297 RSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLEL 356
++++ + +E+++Y P+D K L+ V F D ++G + V ++
Sbjct: 343 ENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEEDI 401
Query: 357 SGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQ 416
R+ FH+ + K L R+I G F FE IVK+Q
Sbjct: 402 RLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQ 461
Query: 417 IVKLKEPSLKCVDLV 431
I L+EP++ + V
Sbjct: 462 IKALEEPAVDMLHTV 476
>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
Length = 715
Score = 223 bits (568), Expect = 6e-58
Identities = 158/440 (35%), Positives = 237/440 (53%), Gaps = 19/440 (4%)
Query: 16 LQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIF 75
L D+ ++G L LP IAV+G QS+GKSSVLE G LPRGSGIVTR PL+L+L
Sbjct: 103 LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTRCPLVLKLKK 161
Query: 76 SKTEH-AEFLHCKSKKFT--DFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNL 132
E A + ++ + D +V +EI + + G +GIS I+L + SP V +L
Sbjct: 162 QPCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDL 221
Query: 133 TLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKE 192
T+IDLPGIT+V V +QP DI QIK +I ++I R+ ++ L V P N+D+A ++AL +A E
Sbjct: 222 TIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHE 281
Query: 193 VDPQGLRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRA 250
VDP+G RTIG++TK DLMD GT+ +V+ N PL++GY+ V R Q++I + +
Sbjct: 282 VDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSLAE 341
Query: 251 ALAAERKFFLSHPAYRHMADR--MGTPHLQKTLNQQLTNHIRESLPALRSKLQSQLLSLE 308
A E FF +HP +R + + P L + L +L HI++SLP L +++ S +
Sbjct: 342 ATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRE---SHQ 398
Query: 309 KEVEEYKNFRPDDPTR---KTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRI 365
K EE + D P++ K L++ ++ F D EK +EG + V E +I
Sbjct: 399 KATEELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEGE-EVVRENETRLYNKIRED 457
Query: 366 FHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKLKEPSL 425
F + + + E+ K G F FE IV + I +L EP+L
Sbjct: 458 FKNWVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPAL 517
Query: 426 ----KCVDLVVSELATVIKK 441
K ++++ V KK
Sbjct: 518 SMLQKAMEIIQQAFINVAKK 537
>gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 135
Score = 122 bits (305), Expect = 2e-27
Identities = 67/125 (53%), Positives = 86/125 (68%), Gaps = 4/125 (3%)
Query: 623 PEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLM----PKTIMHL 678
P + E+G+ SMDPQL Q+ET ++LVDSYVAI+NK++ DLM PKT MHL
Sbjct: 6 PWQASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHL 65
Query: 679 MINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTS 738
MINN FI ELLA LYS D++ LME+S +QA+ ++ L M+H L+EA NIIGDI T+
Sbjct: 66 MINNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 125
Query: 739 TVSTP 743
VS P
Sbjct: 126 MVSMP 130
>gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 135
Score = 122 bits (305), Expect = 2e-27
Identities = 67/125 (53%), Positives = 86/125 (68%), Gaps = 4/125 (3%)
Query: 623 PEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLM----PKTIMHL 678
P + E+G+ SMDPQL Q+ET ++LVDSYVAI+NK++ DLM PKT MHL
Sbjct: 6 PWQASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHL 65
Query: 679 MINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTS 738
MINN FI ELLA LYS D++ LME+S +QA+ ++ L M+H L+EA NIIGDI T+
Sbjct: 66 MINNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 125
Query: 739 TVSTP 743
VS P
Sbjct: 126 MVSMP 130
>gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 155
Score = 122 bits (305), Expect = 2e-27
Identities = 67/125 (53%), Positives = 86/125 (68%), Gaps = 4/125 (3%)
Query: 623 PEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLM----PKTIMHL 678
P + E+G+ SMDPQL Q+ET ++LVDSYVAI+NK++ DLM PKT MHL
Sbjct: 26 PWQASKAEENGSDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHL 85
Query: 679 MINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTS 738
MINN FI ELLA LYS D++ LME+S +QA+ ++ L M+H L+EA NIIGDI T+
Sbjct: 86 MINNMHEFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTT 145
Query: 739 TVSTP 743
VS P
Sbjct: 146 MVSMP 150
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 317 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 376
Query: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
R + + H S++F D +R EIE + +SP
Sbjct: 377 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 436
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 437 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 496
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 497 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 556
Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 557 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 613
Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
S+ ++ +LE E+KN P
Sbjct: 614 SVEQQADSFKATRFNLE---TEWKNNYP 638
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
Query: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
R + + H S++F D +R EIE + +SP
Sbjct: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 539 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595
Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
S+ ++ +LE E+KN P
Sbjct: 596 SVEQQADSFKATRFNLE---TEWKNNYP 620
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
Query: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
R + + H S++F D +R EIE + +SP
Sbjct: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 521 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577
Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
S+ ++ +LE E+KN P
Sbjct: 578 SVEQQADSFKATRFNLE---TEWKNNYP 602
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339
Query: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
R + + H S++F D +R EIE + +SP
Sbjct: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519
Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 520 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576
Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
S+ ++ +LE E+KN P
Sbjct: 577 SVEQQADSFKATRFNLE---TEWKNNYP 601
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
Query: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
R + + H S++F D +R EIE + +SP
Sbjct: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 503 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559
Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
S+ ++ +LE E+KN P
Sbjct: 560 SVEQQADSFKATRFNLE---TEWKNNYP 584
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 244 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 303
Query: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
R + + H S++F D +R EIE + +SP
Sbjct: 304 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 363
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 364 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 423
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 424 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 483
Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 484 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 540
Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
S+ ++ +LE E+KN P
Sbjct: 541 SVEQQADSFKATRFNLE---TEWKNNYP 565
>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
Length = 924
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 226 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 285
Query: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
R + + H S++F D +R EIE + +SP
Sbjct: 286 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 345
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 346 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 405
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 406 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 465
Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 466 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 522
Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
S+ ++ +LE E+KN P
Sbjct: 523 SVEQQADSFKATRFNLE---TEWKNNYP 547
>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
Length = 960
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 262 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 321
Query: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
R + + H S++F D +R EIE + +SP
Sbjct: 322 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 381
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 382 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 441
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 442 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 501
Query: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 502 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 558
Query: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
S+ ++ +LE E+KN P
Sbjct: 559 SVEQQADSFKATRFNLE---TEWKNNYP 583
>gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens]
Length = 105
Score = 90.9 bits (224), Expect = 5e-18
Identities = 49/97 (50%), Positives = 66/97 (68%), Gaps = 13/97 (13%)
Query: 695 LYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQ 754
+YS +Q++LMEE A+QAQ+ D+ML M+HALKEAL+IIGDI+ +TV+ P+PPPVDDTWLQ
Sbjct: 1 MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWLQ 60
Query: 755 SAS---SH-----SPTPQRRPV-----SSIHPPGRPP 778
S +H PT + P S++ G PP
Sbjct: 61 VQSIPDAHRYQRLPPTAPKSPTRDAQRSALGASGTPP 97
>gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo
sapiens]
Length = 63
Score = 87.8 bits (216), Expect = 4e-17
Identities = 39/59 (66%), Positives = 52/59 (88%)
Query: 695 LYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWL 753
+YS +Q++LMEE A+QAQ+ D+ML M+HALKEAL+IIGDI+ +TV+ P+PPPVDDTWL
Sbjct: 1 MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59
>gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo
sapiens]
Length = 63
Score = 87.8 bits (216), Expect = 4e-17
Identities = 39/59 (66%), Positives = 52/59 (88%)
Query: 695 LYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWL 753
+YS +Q++LMEE A+QAQ+ D+ML M+HALKEAL+IIGDI+ +TV+ P+PPPVDDTWL
Sbjct: 1 MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59
>gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo
sapiens]
Length = 103
Score = 83.6 bits (205), Expect = 7e-16
Identities = 48/97 (49%), Positives = 65/97 (67%), Gaps = 15/97 (15%)
Query: 695 LYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQ 754
+YS +Q++LMEE A+QAQ+ D+ML M+HALKEAL+IIGDI+ +TV+ +PPPVDDTWLQ
Sbjct: 1 MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVT--MPPPVDDTWLQ 58
Query: 755 SAS---SH-----SPTPQRRPV-----SSIHPPGRPP 778
S +H PT + P S++ G PP
Sbjct: 59 VQSIPDAHRYQRLPPTAPKSPTRDAQRSALGTSGTPP 95
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 58.5 bits (140), Expect = 3e-08
Identities = 45/130 (34%), Positives = 52/130 (40%), Gaps = 16/130 (12%)
Query: 749 DDTWLQSASSHSPTPQRRPVSSIHPPGRP-PAVRGPTPGPPLIPV----------PVGAA 797
D T S+ +P PQ P S I P P P GP P PPL P P GA
Sbjct: 381 DGTSTASSQQQAP-PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP 439
Query: 798 ASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPP--AAPSRPT 855
P +P GP P P + P P PPG+PPG P R PP P P
Sbjct: 440 PFLRPPGMPGLRGPLPRLLPPG--PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPP 497
Query: 856 IIRPAEPSLL 865
I P P ++
Sbjct: 498 GIPPPRPGMM 507
Score = 53.5 bits (127), Expect = 8e-07
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 19/160 (11%)
Query: 706 EESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQR 765
E+ +D ++ + + KE + G + S+ P V + +Q+ P P
Sbjct: 358 EDDSDDSEAEKQSQKQH---KEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLG 414
Query: 766 RPVSS-IHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAP 824
P + + PPG PP P P P GA P +P GP L P P
Sbjct: 415 PPPAPPLRPPG-PPTGLPPGP-------PPGAPPFLRPPGMPGLRGPLPRL----LPPGP 462
Query: 825 PQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSL 864
P P RP PPG PPG+P PP P P + PA P +
Sbjct: 463 P--PGRPPGPPPGPPPGLPPGPPPRGPP-PRLPPPAPPGI 499
Score = 46.2 bits (108), Expect = 1e-04
Identities = 38/120 (31%), Positives = 47/120 (39%), Gaps = 13/120 (10%)
Query: 743 PVPPPVDDTWLQSASS---HSPTPQRRPVSSIHPPGRPPAVR-GPTPGPPLIPVPVGAAA 798
P PPP +L+ P P+ P PPGRPP GP PG P P P G
Sbjct: 432 PGPPPGAPPFLRPPGMPGLRGPLPRLLPPGP--PPGRPPGPPPGPPPGLPPGPPPRGPPP 489
Query: 799 SFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIPPGVPSRRPPAAPSRPTIIR 858
P P P P+ L PP P+ PPG+ P P P + P +I+
Sbjct: 490 RLPPPAPPGIPPPRPGMMRPPL--VPPLGPA-----PPGLFPPAPLPNPGVLSAPPNLIQ 542
Score = 40.4 bits (93), Expect = 0.007
Identities = 32/93 (34%), Positives = 37/93 (39%), Gaps = 12/93 (12%)
Query: 743 PVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVP-VGAAASFS 801
P PPP P P P PP R P R P P PP IP P G
Sbjct: 460 PGPPP--------GRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL 511
Query: 802 APPI-PSRPG--PQSVFANSDLFPAPPQIPSRP 831
PP+ P+ PG P + N + APP + RP
Sbjct: 512 VPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRP 544
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,926,752
Number of Sequences: 37866
Number of extensions: 1969893
Number of successful extensions: 21262
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 259
Number of HSP's successfully gapped in prelim test: 1101
Number of HSP's that attempted gapping in prelim test: 11795
Number of HSP's gapped (non-prelim): 6142
length of query: 866
length of database: 18,247,518
effective HSP length: 111
effective length of query: 755
effective length of database: 14,044,392
effective search space: 10603515960
effective search space used: 10603515960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.