Search of human proteins with 56549091

Search of human proteins with 56549091

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56549091 B-cell receptor-associated protein BAP29 isoform b
[Homo sapiens]
         (241 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56549091 B-cell receptor-associated protein BAP29 isoform b [...   474   e-134
gi|56549093 B-cell receptor-associated protein BAP29 isoform a [...   452   e-128
gi|32171186 B-cell receptor-associated protein 31 isoform b [Hom...   224   4e-59
gi|213511508 B-cell receptor-associated protein 31 isoform a [Ho...   224   4e-59
gi|213511012 B-cell receptor-associated protein 31 isoform b [Ho...   224   4e-59
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...    45   6e-05
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C...    45   6e-05
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi...    45   6e-05
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...    45   7e-05
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    44   1e-04
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    44   2e-04
gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo sap...    43   2e-04
gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo sapi...    43   2e-04
gi|134152708 arginine and glutamate rich 1 [Homo sapiens]              43   2e-04
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap...    42   4e-04
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           42   4e-04
gi|148746195 trichohyalin [Homo sapiens]                               42   6e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    42   6e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    42   6e-04
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]              41   8e-04
gi|58530840 desmoplakin isoform I [Homo sapiens]                       41   0.001
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]          41   0.001
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    40   0.002
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         40   0.002
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        40   0.002
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        40   0.002
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         40   0.002
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         40   0.002
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         40   0.002
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         40   0.002

>gi|56549091 B-cell receptor-associated protein BAP29 isoform b
           [Homo sapiens]
          Length = 241

 Score =  474 bits (1220), Expect = e-134
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
           MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI
Sbjct: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60

Query: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
           VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL
Sbjct: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120

Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL 180
           VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL
Sbjct: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL 180

Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
           VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR
Sbjct: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240

Query: 241 L 241
           L
Sbjct: 241 L 241


>gi|56549093 B-cell receptor-associated protein BAP29 isoform a
           [Homo sapiens]
          Length = 348

 Score =  452 bits (1164), Expect = e-128
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
           MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI
Sbjct: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60

Query: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
           VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL
Sbjct: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120

Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL 180
           VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL
Sbjct: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL 180

Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
           VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ
Sbjct: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230


>gi|32171186 B-cell receptor-associated protein 31 isoform b [Homo
           sapiens]
          Length = 246

 Score =  224 bits (572), Expect = 4e-59
 Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)

Query: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
           M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF   +   + ++ N  F+ +I++L+
Sbjct: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60

Query: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
           +L +DAVRE+RKY  V T + +  + P A EH  MKLFR+QRNLYI+GFSL    +LRRL
Sbjct: 61  LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 119

Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175
           VTLI+Q A  L++    K QAE+ ++AAKK+MEEN++LK+     G      + E  LE 
Sbjct: 120 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 179

Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
           EN+ L  D +KLK EL  T   L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 180 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 234


>gi|213511508 B-cell receptor-associated protein 31 isoform a [Homo
           sapiens]
          Length = 313

 Score =  224 bits (572), Expect = 4e-59
 Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)

Query: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
           M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF   +   + ++ N  F+ +I++L+
Sbjct: 68  MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 127

Query: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
           +L +DAVRE+RKY  V T + +  + P A EH  MKLFR+QRNLYI+GFSL    +LRRL
Sbjct: 128 LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 186

Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175
           VTLI+Q A  L++    K QAE+ ++AAKK+MEEN++LK+     G      + E  LE 
Sbjct: 187 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 246

Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
           EN+ L  D +KLK EL  T   L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 247 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 301


>gi|213511012 B-cell receptor-associated protein 31 isoform b [Homo
           sapiens]
          Length = 246

 Score =  224 bits (572), Expect = 4e-59
 Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)

Query: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
           M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF   +   + ++ N  F+ +I++L+
Sbjct: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60

Query: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
           +L +DAVRE+RKY  V T + +  + P A EH  MKLFR+QRNLYI+GFSL    +LRRL
Sbjct: 61  LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 119

Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175
           VTLI+Q A  L++    K QAE+ ++AAKK+MEEN++LK+     G      + E  LE 
Sbjct: 120 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 179

Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
           EN+ L  D +KLK EL  T   L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 180 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 234


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 13/112 (11%)

Query: 134 KGVLKTQAENT------NKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKL 187
           +G L++Q EN       +K  K+ ++E E++ R       ++E     E ++L E  E+L
Sbjct: 315 EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLR-------EQEAQRVREQERLCEQNERL 367

Query: 188 KTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
           + + +   +   + +     ++ Q ERL KE ++L K+   L D+ ER  KK
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKK 419



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 24/112 (21%), Positives = 57/112 (50%), Gaps = 7/112 (6%)

Query: 136 VLKTQAENTNKAAKKFMEENEKLK---RILKSHG---KDEECVLEAENKKLVEDQEKLKT 189
           +L+ Q     +  ++  E+NE+L+   + L+  G   + +E  L  + ++L +++E+L+ 
Sbjct: 345 MLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQK 404

Query: 190 ELRKTSDALSKAQNDVMEMKMQSERLS-KEYDQLLKEHSELQDRLERGNKKR 240
           + ++  D   +       ++ Q ERL+  +  +L K+ +E Q   E  N ++
Sbjct: 405 QEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEK 456


>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
           isoform 1 [Homo sapiens]
          Length = 693

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 13/112 (11%)

Query: 134 KGVLKTQAENT------NKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKL 187
           +G L++Q EN       +K  K+ ++E E++ R       ++E     E ++L E  E+L
Sbjct: 315 EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLR-------EQEAQRVREQERLCEQNERL 367

Query: 188 KTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
           + + +   +   + +     ++ Q ERL KE ++L K+   L D+ ER  KK
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKK 419



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 24/112 (21%), Positives = 57/112 (50%), Gaps = 7/112 (6%)

Query: 136 VLKTQAENTNKAAKKFMEENEKLK---RILKSHG---KDEECVLEAENKKLVEDQEKLKT 189
           +L+ Q     +  ++  E+NE+L+   + L+  G   + +E  L  + ++L +++E+L+ 
Sbjct: 345 MLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQK 404

Query: 190 ELRKTSDALSKAQNDVMEMKMQSERLS-KEYDQLLKEHSELQDRLERGNKKR 240
           + ++  D   +       ++ Q ERL+  +  +L K+ +E Q   E  N ++
Sbjct: 405 QEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEK 456


>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
           sapiens]
          Length = 693

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 13/112 (11%)

Query: 134 KGVLKTQAENT------NKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKL 187
           +G L++Q EN       +K  K+ ++E E++ R       ++E     E ++L E  E+L
Sbjct: 315 EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLR-------EQEAQRVREQERLCEQNERL 367

Query: 188 KTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
           + + +   +   + +     ++ Q ERL KE ++L K+   L D+ ER  KK
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKK 419



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 24/112 (21%), Positives = 57/112 (50%), Gaps = 7/112 (6%)

Query: 136 VLKTQAENTNKAAKKFMEENEKLK---RILKSHG---KDEECVLEAENKKLVEDQEKLKT 189
           +L+ Q     +  ++  E+NE+L+   + L+  G   + +E  L  + ++L +++E+L+ 
Sbjct: 345 MLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQK 404

Query: 190 ELRKTSDALSKAQNDVMEMKMQSERLS-KEYDQLLKEHSELQDRLERGNKKR 240
           + ++  D   +       ++ Q ERL+  +  +L K+ +E Q   E  N ++
Sbjct: 405 QEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEK 456


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 13/112 (11%)

Query: 134 KGVLKTQAENT------NKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKL 187
           +G L++Q EN       +K  K+ ++E E++ R       ++E     E ++L E  E+L
Sbjct: 315 EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLR-------EQEVQRVREQERLCEQNERL 367

Query: 188 KTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
           + + +   +   + +     ++ Q ERL KE ++L K+   L D+ ER  KK
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKK 419



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 24/112 (21%), Positives = 57/112 (50%), Gaps = 7/112 (6%)

Query: 136 VLKTQAENTNKAAKKFMEENEKLK---RILKSHG---KDEECVLEAENKKLVEDQEKLKT 189
           +L+ Q     +  ++  E+NE+L+   + L+  G   + +E  L  + ++L +++E+L+ 
Sbjct: 345 MLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQK 404

Query: 190 ELRKTSDALSKAQNDVMEMKMQSERLS-KEYDQLLKEHSELQDRLERGNKKR 240
           + ++  D   +       ++ Q ERL+  +  +L K+ +E Q   E  N ++
Sbjct: 405 QEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEK 456


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 24/105 (22%), Positives = 56/105 (53%), Gaps = 20/105 (19%)

Query: 150 KFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMK 209
           K++++   +K+++K + K +E  ++     +  +++ L+ EL+K ++   +  N + +++
Sbjct: 201 KYLQQEHIIKKLIKENKKHQELFVD-----ICSEKDNLREELKKRTETEKQHMNTIKQLE 255

Query: 210 MQSERLSKEY----DQLLKE-----------HSELQDRLERGNKK 239
            + E L+KE     DQL+ +           H E+  R+E+ NKK
Sbjct: 256 SRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKK 300



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 17/105 (16%)

Query: 138 KTQAENTNKAAKKFMEEN-EKLKRILKSHGKDEEC--VLEAENKKLVEDQEKLKTELRKT 194
           K   E   + A K +E+N  K+K++ +  G+  +     E E  +L+ + +KLK ++   
Sbjct: 329 KETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDI--- 385

Query: 195 SDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
                   + V+++K    +L  E D     H E +D+L+    K
Sbjct: 386 -------NSHVIKVKWAQNKLKAEMD----SHKETKDKLKETTTK 419



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 36/172 (20%), Positives = 71/172 (41%), Gaps = 20/172 (11%)

Query: 79  IEKSSTSRPDAYE--HTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKE-LSNKG 135
           +EK    + D  E  H ++K     +  +  G        LR L T +  L  E L  + 
Sbjct: 463 LEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMD-----ELRTLRTKVKCLEDERLRTED 517

Query: 136 VLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAEN-KKLVEDQEKLKTELRKT 194
            L    E  N+   +     +K+K   +   + +    E EN K+ VE    L  +L+K 
Sbjct: 518 ELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKD 577

Query: 195 SDALSKAQNDVM-----------EMKMQSERLSKEYDQLLKEHSELQDRLER 235
            +   K +++++           +++ +S  L  ++D++    S+LQ + E+
Sbjct: 578 IEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQ 629


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 5/106 (4%)

Query: 138  KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECV--LEAENKKLVEDQEKLKTELRKTS 195
            K   +   + + +  EE EK K + K   K E  +  LE   KK  + +++L+   RK  
Sbjct: 1002 KLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD 1061

Query: 196  DALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKRL 241
               +  Q+ + E++ Q + L     QL K+  ELQ  L RG+ + L
Sbjct: 1062 GETTDLQDQIAELQAQIDELKL---QLAKKEEELQGALARGDDETL 1104



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 24/93 (25%), Positives = 52/93 (55%), Gaps = 6/93 (6%)

Query: 153  EENEKLKRILKSHGKDEECVLEAENKK---LVEDQEKLKTELRKTS---DALSKAQNDVM 206
            E+NE+ KR+L    ++ E  LE E K+    V  ++K++ +L+      +A +KA+++V+
Sbjct: 1585 EQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVI 1644

Query: 207  EMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
            +   + +   K+Y + L+E    +D +   +K+
Sbjct: 1645 KQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677



 Score = 34.7 bits (78), Expect = 0.076
 Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 13/156 (8%)

Query: 91   EHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELSNK-----GVLKTQAENT- 144
            E T+ +L +++R L   G +      +  L   I +L  +L+ K     G L    + T 
Sbjct: 1047 EKTRQELEKAKRKL--DGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETL 1104

Query: 145  --NKAAKKFMEENEKLKRILKSHGKDEECVLEAENKK--LVEDQEKLKTELRKTSDALSK 200
              N A K   E   ++  + +    ++    +AE +K  L E+ E LKTEL  T D  + 
Sbjct: 1105 HKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAA 1164

Query: 201  AQNDVMEMKMQSERLSKEYDQLLKEH-SELQDRLER 235
             Q    + + +   L K  ++  K H +++QD  +R
Sbjct: 1165 QQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200



 Score = 31.2 bits (69), Expect = 0.84
 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 17/123 (13%)

Query: 117  LRRLVTLITQLAKELSNKGVLKTQAEN---------TNKAAKKFMEENEKLKRILKSHGK 167
            L+ L   I QL +EL++    +  AE          TN A+ K    +EK +   +    
Sbjct: 1682 LKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQL 1741

Query: 168  DEECVLEAENKKLVEDQ--------EKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEY 219
            +EE   E  N +L+ D+        + L  EL     A  K+ N   +++ Q++ L  + 
Sbjct: 1742 EEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKL 1801

Query: 220  DQL 222
             +L
Sbjct: 1802 QEL 1804



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 11/111 (9%)

Query: 134  KGVLKTQAENTNKAAKKFMEENEK---LKRILKSHGKDEECVLEAENKKLVEDQEKLKTE 190
            K +    AE  ++A  +  E+  K   L R L+   + +E   E +NK+L  D E    +
Sbjct: 1461 KSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE-EFERQNKQLRADME----D 1515

Query: 191  LRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKRL 241
            L  + D + K   +V E++     L ++ +++  +  EL+D L+     +L
Sbjct: 1516 LMSSKDDVGK---NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL 1563


>gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo
           sapiens]
          Length = 698

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/155 (25%), Positives = 72/155 (46%), Gaps = 11/155 (7%)

Query: 73  YSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELS 132
           +S       + T   D  +HT+  + +S R + + G    + LV R   T   +L +E  
Sbjct: 95  FSPASPATPNGTKGKDESQHTESMVLQSSRGIKVEGCVRMYELVHRMKGTEGLRLWQEEQ 154

Query: 133 NKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC--VLEAENKKLVEDQEKLKTE 190
            + V +  +E  ++  K+F E  E     LK H + ++   V+E  +++ +  QEKLK E
Sbjct: 155 ERKV-QALSEMASEQLKRFDEWKE-----LKQHKEFQDLREVMEKSSREALGHQEKLKAE 208

Query: 191 LRKTSDALSKAQNDVMEMKM---QSERLSKEYDQL 222
            R  +  L+    +  + ++   + ERL KE  Q+
Sbjct: 209 HRHRAKILNLKLREAEQQRVKQAEQERLRKEEGQI 243


>gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo
           sapiens]
          Length = 659

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/155 (25%), Positives = 72/155 (46%), Gaps = 11/155 (7%)

Query: 73  YSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELS 132
           +S       + T   D  +HT+  + +S R + + G    + LV R   T   +L +E  
Sbjct: 95  FSPASPATPNGTKGKDESQHTESMVLQSSRGIKVEGCVRMYELVHRMKGTEGLRLWQEEQ 154

Query: 133 NKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC--VLEAENKKLVEDQEKLKTE 190
            + V +  +E  ++  K+F E  E     LK H + ++   V+E  +++ +  QEKLK E
Sbjct: 155 ERKV-QALSEMASEQLKRFDEWKE-----LKQHKEFQDLREVMEKSSREALGHQEKLKAE 208

Query: 191 LRKTSDALSKAQNDVMEMKM---QSERLSKEYDQL 222
            R  +  L+    +  + ++   + ERL KE  Q+
Sbjct: 209 HRHRAKILNLKLREAEQQRVKQAEQERLRKEEGQI 243


>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
          Length = 273

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 9/108 (8%)

Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
           VLRR+      + K+L  +   + QAE    AA+K  EE E+ KR      ++ E +LE 
Sbjct: 157 VLRRVEEAKRIMEKQLLEELERQRQAE---LAAQKAREEEERAKR------EELERILEE 207

Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLL 223
            N+K+ E Q KL  E  +  +   K   + M+++ + +R  KE  +++
Sbjct: 208 NNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKII 255


>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
           sapiens]
          Length = 955

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 40/191 (20%), Positives = 86/191 (45%), Gaps = 27/191 (14%)

Query: 76  VHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELSNKG 135
           +  +EK   +    +E+ Q++ F+ +    I+        +   L+ + +Q  ++L   G
Sbjct: 694 IENLEKQLRAANMEHEN-QIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELG 752

Query: 136 VLKTQAENTNK-----AAKKFMEENEKLK-RILKSHGKDEECVLEAENKKLVEDQEKLKT 189
           +L+ + +            K   E+EK+K  + K+H  + E  LE  N KL + +++   
Sbjct: 753 LLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQ 812

Query: 190 ELRKTSDALSKAQNDVMEMKMQS---------------ERLSKEYDQLLKEHSE----LQ 230
           +L K+S  +++ Q  +  +K ++               ++   E  QL++++ +    LQ
Sbjct: 813 KLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQ 872

Query: 231 DRLE-RGNKKR 240
           D LE R N+ R
Sbjct: 873 DELENRSNQVR 883



 Score = 27.7 bits (60), Expect = 9.3
 Identities = 19/90 (21%), Positives = 45/90 (50%), Gaps = 13/90 (14%)

Query: 145 NKAAKKFMEENEKLKRILKS-HGKDEECVLEAEN-----KKLVEDQEKLKTELRKTSDAL 198
           NK   ++M + +    ++K    + ++   EAEN     +KL++++ +L+   + T    
Sbjct: 393 NKMESEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITC--- 449

Query: 199 SKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
               +++ E+K +   L KE D L+ ++ +
Sbjct: 450 ----SELQEVKARRNTLHKEKDHLVNDYEQ 475


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 30/127 (23%), Positives = 60/127 (47%), Gaps = 8/127 (6%)

Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
           +L  +V L   LA+    +   +   E    A  +F +E ++ +       + +E  LE 
Sbjct: 165 LLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKE-KLEK 223

Query: 176 ENKKLVEDQEKLKTELR-------KTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
           E K++  D +  +TE++       K+ + L K +  + E K+ +ER +KE +Q    +++
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAK 283

Query: 229 LQDRLER 235
           LQ   E+
Sbjct: 284 LQQENEQ 290


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 12/116 (10%)

Query: 130 ELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKT 189
           EL  KG  + Q +   +  + F EE EK         +  E VL  E +KL E++ + + 
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEK-------EWRKRETVLRKEEEKLQEEEPQRQR 269

Query: 190 ELRKTSDALSKAQNDVM-----EMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
           EL++  + L K +   +     E + Q +RL +E     K+  E +++ E   +++
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325



 Score = 35.4 bits (80), Expect = 0.045
 Identities = 27/116 (23%), Positives = 56/116 (48%), Gaps = 17/116 (14%)

Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKS--------HGKDEECVLEAENKKLVED--QEK 186
           L+ + E   +   K  EE E+L++ L+S          + E+ +   E K+L ++  +++
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566

Query: 187 LKTELRKTSDALSKAQNDVMEMKMQSE-------RLSKEYDQLLKEHSELQDRLER 235
           LK E  +  D L K + +  + +++ E       RL +E  + L++    + RL+R
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622



 Score = 35.4 bits (80), Expect = 0.045
 Identities = 25/99 (25%), Positives = 51/99 (51%), Gaps = 6/99 (6%)

Query: 149  KKFMEENEKLKRILKSHG-KDEECVLEAENKKLVEDQEKLKTELRK----TSDALSKAQN 203
            +KF+EE ++L+R  +    +++E   +   +K +E++++L  + R+      +   + Q 
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544

Query: 204  DVMEMKMQSERLSKEYDQLLKEHSELQ-DRLERGNKKRL 241
               + +   +R  +E +QL +E  E Q  R ER  K RL
Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583



 Score = 32.7 bits (73), Expect = 0.29
 Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 5/103 (4%)

Query: 138 KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDA 197
           ++Q +  ++  +  +EE  K +R         +  L  E + L E++E+L+ E R+    
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE---- 919

Query: 198 LSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
             + + +      + E+L +E +QLL+E  E + R ER  + R
Sbjct: 920 -KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 5/115 (4%)

Query: 126  QLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQE 185
            QL +E   K   +       K  +   EE + L+   +     E      E ++L +++E
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061

Query: 186  KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            +L  E R+T     + + ++     + E L +E +QLL+E  E + R ER  + R
Sbjct: 1062 QLLGEERET-----RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 6/100 (6%)

Query: 142 ENTNKAAKKFMEENEKLKRILKSHGKDEECVLE-AENKKLVEDQEKLKTELRKTSDALSK 200
           E   K  +   EE E+L+R  +   + +E   +  E ++L +++E+L  E R+      +
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE-----KR 951

Query: 201 AQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            + +      + ++L ++ +QLL E  E + R ER  K R
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991



 Score = 31.2 bits (69), Expect = 0.84
 Identities = 24/106 (22%), Positives = 57/106 (53%), Gaps = 15/106 (14%)

Query: 149  KKFMEENEKLKRILKSHGKDEECVL----------EAENKKLVEDQEKLKTEL--RKTSD 196
            +KF+EE ++L++      ++EE +L          +  ++K +E++++L+ +   RK  +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505

Query: 197  ALSKAQNDVMEMKMQSERLSKEYDQ--LLKEHSELQDRLERGNKKR 240
               ++Q    +   + ++L ++  Q   L+E  +L+ R ERG ++R
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLR-RQERGQQRR 1550



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 19/113 (16%), Positives = 53/113 (46%)

Query: 128  AKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKL 187
            ++E   K + + Q  +  +  +KF++E ++L+R  +   + ++   +   ++ +  + + 
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569

Query: 188  KTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            +   R+  D   + +   +  + Q  +  ++  QL ++  + Q R ER  K R
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR 1622



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 30/130 (23%)

Query: 142 ENTNKAAKKFMEENEKLKRILK---------SHGKDEECVLEAENK-----KLVEDQEKL 187
           +   K   K  +E E+ +R LK            ++++   E E +     K  E++E+L
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528

Query: 188 KTELR-----------KTSDALSKAQNDVMEMKMQSERLSKEY----DQLLK-EHSELQD 231
           +  LR           +    L + +   +E + + +RL +E     DQLLK E    Q 
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588

Query: 232 RLERGNKKRL 241
           RL+R  ++RL
Sbjct: 589 RLKREQEERL 598



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 15/89 (16%)

Query: 153  EENEKLKRI-LKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQ 211
            EE EK +R  L+   ++EE V + E + L E+ EK             + + ++     +
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEK-------------RRRQELERQYRE 1172

Query: 212  SERLSKEYDQLLKEHSELQDRLERGNKKR 240
             E L +E +QLL+E  E + R ER  + R
Sbjct: 1173 EEELQQEEEQLLREEQE-KRRQERERQYR 1200



 Score = 28.9 bits (63), Expect = 4.2
 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 12/82 (14%)

Query: 153  EENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQS 212
            EE EK +R      ++ +C    E ++L +++E+L  E R+      + + ++     + 
Sbjct: 1096 EEPEKRRR----QERERQC---REEEELQQEEEQLLREERE-----KRRRQELERQYREE 1143

Query: 213  ERLSKEYDQLLKEHSELQDRLE 234
            E + +E +QLL+E  E + R E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQE 1165



 Score = 28.5 bits (62), Expect = 5.5
 Identities = 24/118 (20%), Positives = 55/118 (46%), Gaps = 7/118 (5%)

Query: 129  KELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC---VLEAENKKLVEDQE 185
            +E   K + + Q     +  +KF EE +  +   +   + +E    +LE E  +   +++
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762

Query: 186  KLKTELR----KTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
            +L+ + R    +  + L + + +      +S+R  +E +QL +E  E Q R ++ + K
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820



 Score = 27.7 bits (60), Expect = 9.3
 Identities = 19/93 (20%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 140 QAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALS 199
           Q E   +  K+   E E+ +++LKS  ++E    +   ++    +++LK E         
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE--------- 662

Query: 200 KAQNDVMEMKMQSERLSKEYDQLLKEHSELQDR 232
             + + +E +++ E   +  +Q L E  + Q R
Sbjct: 663 -EEEERLEQRLKREHEEERREQELAEEEQEQAR 694



 Score = 27.7 bits (60), Expect = 9.3
 Identities = 22/98 (22%), Positives = 48/98 (48%), Gaps = 6/98 (6%)

Query: 138  KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLE-AENKKLVEDQEKLKTELRKTSD 196
            + + E   +  ++  +E E+L R  +   + +E   +  ++KKL + +E+L  E     +
Sbjct: 923  RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE-----E 977

Query: 197  ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLE 234
               + + +  +   + E L +E +QLL+E  E + R E
Sbjct: 978  PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 13/116 (11%)

Query: 126 QLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSH--GKDEECVLEAENKKLVED 183
           +L K L +   L  Q E+  K   +  EEN +L+R ++S      +   L+ ENK+L  +
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733

Query: 184 QEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
           +E+LK  L     +  K           +ERL   Y  L  E+  LQ  LE  NKK
Sbjct: 734 KEQLKKGLELLKASFKK-----------TERLEVSYQGLDIENQRLQKTLENSNKK 778



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 11/128 (8%)

Query: 117 LRRLVTLITQLAKELSN-KGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
           L+    L   L KE +  +  ++T  EN+ +  K   +ENE L + + S  +  +   EA
Sbjct: 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580

Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQ----------SERLSKEYDQLLKE 225
             K + ++ + L   +++TS  LSK + +  ++K +          +E L  E   L KE
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640

Query: 226 HSELQDRL 233
           +  LQ ++
Sbjct: 641 NELLQKKI 648



 Score = 36.2 bits (82), Expect = 0.026
 Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 15/117 (12%)

Query: 129 KELSNKGV--LKTQAENTNKAAKKFME---ENEKLKRILKSHGKDEECV------LEAEN 177
           KE   KG+  LK   + T +    +     EN++L++ L++  K  + +      LE EN
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793

Query: 178 KKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLE 234
           + L ++ E+LK     +S  L + + +   ++ ++ +L K+  QL KE+  L+ + E
Sbjct: 794 QTLQKNLEELKI----SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 15/115 (13%)

Query: 130 ELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVL--EAENKKLVEDQEKL 187
           EL++  +LK + EN     +   +  E+L+  + S   +   +L  E EN++L +  E L
Sbjct: 456 ELTSSRLLKLEMEN-----QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510

Query: 188 KTELRKTSDALSKAQN---DVMEMKMQSERLSKEYDQLLKEHSELQDR-LERGNK 238
           + E+ +   +L   QN   D+M+ K Q E+      + L+E+SE Q + LE+ N+
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTI----ETLRENSERQIKILEQENE 561



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 2/78 (2%)

Query: 153  EENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQS 212
            E  E  + +LK   KD    +E  N  L  +++ LKT+L++     +  Q  ++ ++ Q+
Sbjct: 1033 ESQETTRELLKV--KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1090

Query: 213  ERLSKEYDQLLKEHSELQ 230
              L ++   L  ++++LQ
Sbjct: 1091 VSLQEQNTTLQTQNAKLQ 1108



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 40/180 (22%), Positives = 75/180 (41%), Gaps = 24/180 (13%)

Query: 65   DAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLI 124
            D + EV + ++    EK +         TQ+K   +Q N            + R+ V+L 
Sbjct: 1046 DRLIEVERNNATLQAEKQALK-------TQLKQLETQNN----NLQAQILALQRQTVSLQ 1094

Query: 125  TQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVL-EAENKK---- 179
             Q     +    L+ +    N  +   M +N +L     S   + E V+ E E+ K    
Sbjct: 1095 EQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYD 1154

Query: 180  -LVEDQEKLKT----ELRKTSDALSK---AQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
             L++D EKL+     +  +    +SK    ++    ++++   L   Y+QLLK+  +L+D
Sbjct: 1155 SLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLED 1214



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 27/112 (24%), Positives = 56/112 (50%), Gaps = 11/112 (9%)

Query: 138 KTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC---VLEAENKKLVEDQEKLKTELRKT 194
           K   +N    +K  M+E  +L++ +++  ++ E    +LE EN+ L +    L+   + +
Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS 577

Query: 195 SDALSK---AQNDVM--EMKMQSERLSK---EYDQLLKEHSELQDRLERGNK 238
           ++A  K    +N ++   +K  S +LSK   E  Q+ KE    +++ ER  +
Sbjct: 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE 629



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 8/124 (6%)

Query: 119  RLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENK 178
            RL+ +    A   + K  LKTQ +           +   L+R   S  +++   L+ +N 
Sbjct: 1047 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNA 1105

Query: 179  KLVEDQEKLKTE----LRKTSDAL---SKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
            KL  +   L ++    + + +  L   S  +N+   +  + E L   YD L+K+H +L+ 
Sbjct: 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1165

Query: 232  RLER 235
              ER
Sbjct: 1166 LHER 1169



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 38/138 (27%), Positives = 58/138 (42%), Gaps = 31/138 (22%)

Query: 123  LITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLK-----------RILKSHG--KDE 169
            LI Q + E  N+ V+K + E+        ++++EKL+            ++  HG  K  
Sbjct: 1129 LIQQSSLENENESVIK-EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSA 1187

Query: 170  ECVLEAENKKL-------------VEDQEK-LKTELRKTSDALSKAQNDVMEMKM---QS 212
               LE E++ L             +ED EK LK E  K        +    E K    ++
Sbjct: 1188 HKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEN 1247

Query: 213  ERLSKEYDQLLKEHSELQ 230
            +RL+  Y QLLKE   LQ
Sbjct: 1248 DRLNHTYSQLLKETEVLQ 1265



 Score = 27.7 bits (60), Expect = 9.3
 Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 15/99 (15%)

Query: 138  KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLK---TELRKT 194
            K Q E+  K  K    E EK+    K+H       + AE KKL  + ++L    ++L K 
Sbjct: 1209 KGQLEDLEKMLKV---EQEKMLLENKNHE-----TVAAEYKKLCGENDRLNHTYSQLLKE 1260

Query: 195  SDALSKAQNDVMEM----KMQSERLSKEYDQLLKEHSEL 229
            ++ L     ++  +    K++  RL  E+ +L +++ +L
Sbjct: 1261 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQL 1299


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 13/116 (11%)

Query: 126 QLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSH--GKDEECVLEAENKKLVED 183
           +L K L +   L  Q E+  K   +  EEN +L+R ++S      +   L+ ENK+L  +
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733

Query: 184 QEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
           +E+LK  L     +  K           +ERL   Y  L  E+  LQ  LE  NKK
Sbjct: 734 KEQLKKGLELLKASFKK-----------TERLEVSYQGLDIENQRLQKTLENSNKK 778



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 11/128 (8%)

Query: 117 LRRLVTLITQLAKELSN-KGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
           L+    L   L KE +  +  ++T  EN+ +  K   +ENE L + + S  +  +   EA
Sbjct: 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580

Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQ----------SERLSKEYDQLLKE 225
             K + ++ + L   +++TS  LSK + +  ++K +          +E L  E   L KE
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640

Query: 226 HSELQDRL 233
           +  LQ ++
Sbjct: 641 NELLQKKI 648



 Score = 36.2 bits (82), Expect = 0.026
 Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 15/117 (12%)

Query: 129 KELSNKGV--LKTQAENTNKAAKKFME---ENEKLKRILKSHGKDEECV------LEAEN 177
           KE   KG+  LK   + T +    +     EN++L++ L++  K  + +      LE EN
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793

Query: 178 KKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLE 234
           + L ++ E+LK     +S  L + + +   ++ ++ +L K+  QL KE+  L+ + E
Sbjct: 794 QTLQKNLEELKI----SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 15/115 (13%)

Query: 130 ELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVL--EAENKKLVEDQEKL 187
           EL++  +LK + EN     +   +  E+L+  + S   +   +L  E EN++L +  E L
Sbjct: 456 ELTSSRLLKLEMEN-----QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510

Query: 188 KTELRKTSDALSKAQN---DVMEMKMQSERLSKEYDQLLKEHSELQDR-LERGNK 238
           + E+ +   +L   QN   D+M+ K Q E+      + L+E+SE Q + LE+ N+
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTI----ETLRENSERQIKILEQENE 561



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 2/78 (2%)

Query: 153  EENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQS 212
            E  E  + +LK   KD    +E  N  L  +++ LKT+L++     +  Q  ++ ++ Q+
Sbjct: 1032 ESQETTRELLKV--KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1089

Query: 213  ERLSKEYDQLLKEHSELQ 230
              L ++   L  ++++LQ
Sbjct: 1090 VSLQEQNTTLQTQNAKLQ 1107



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 40/180 (22%), Positives = 75/180 (41%), Gaps = 24/180 (13%)

Query: 65   DAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLI 124
            D + EV + ++    EK +         TQ+K   +Q N            + R+ V+L 
Sbjct: 1045 DRLIEVERNNATLQAEKQALK-------TQLKQLETQNN----NLQAQILALQRQTVSLQ 1093

Query: 125  TQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVL-EAENKK---- 179
             Q     +    L+ +    N  +   M +N +L     S   + E V+ E E+ K    
Sbjct: 1094 EQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYD 1153

Query: 180  -LVEDQEKLKT----ELRKTSDALSK---AQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
             L++D EKL+     +  +    +SK    ++    ++++   L   Y+QLLK+  +L+D
Sbjct: 1154 SLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLED 1213



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 25/134 (18%)

Query: 129 KELSNKGVLK-TQAENTNKAAKKFMEENEKLKRILKSHGKDEECV----LEAENKKLV-- 181
           K L  +  +K T  E  N       +EN+ L + +  +   E CV    LE ENK+LV  
Sbjct: 839 KRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY--KESCVRLKELEKENKELVKR 896

Query: 182 ------------ED--QEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHS 227
                       ED   EKLKT+  + ++ L K  +++ ++ +  ERL  +       + 
Sbjct: 897 ATIDIKTLVTLREDLVSEKLKTQ--QMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYK 954

Query: 228 ELQDRLERGNKKRL 241
            L+ +LE   KK L
Sbjct: 955 LLESKLESTLKKSL 968



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 27/112 (24%), Positives = 56/112 (50%), Gaps = 11/112 (9%)

Query: 138 KTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC---VLEAENKKLVEDQEKLKTELRKT 194
           K   +N    +K  M+E  +L++ +++  ++ E    +LE EN+ L +    L+   + +
Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS 577

Query: 195 SDALSK---AQNDVM--EMKMQSERLSK---EYDQLLKEHSELQDRLERGNK 238
           ++A  K    +N ++   +K  S +LSK   E  Q+ KE    +++ ER  +
Sbjct: 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE 629



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 8/124 (6%)

Query: 119  RLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENK 178
            RL+ +    A   + K  LKTQ +           +   L+R   S  +++   L+ +N 
Sbjct: 1046 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNA 1104

Query: 179  KLVEDQEKLKTE----LRKTSDAL---SKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
            KL  +   L ++    + + +  L   S  +N+   +  + E L   YD L+K+H +L+ 
Sbjct: 1105 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1164

Query: 232  RLER 235
              ER
Sbjct: 1165 LHER 1168



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 38/138 (27%), Positives = 58/138 (42%), Gaps = 31/138 (22%)

Query: 123  LITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLK-----------RILKSHG--KDE 169
            LI Q + E  N+ V+K + E+        ++++EKL+            ++  HG  K  
Sbjct: 1128 LIQQSSLENENESVIK-EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSA 1186

Query: 170  ECVLEAENKKL-------------VEDQEK-LKTELRKTSDALSKAQNDVMEMKM---QS 212
               LE E++ L             +ED EK LK E  K        +    E K    ++
Sbjct: 1187 HKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEN 1246

Query: 213  ERLSKEYDQLLKEHSELQ 230
            +RL+  Y QLLKE   LQ
Sbjct: 1247 DRLNHTYSQLLKETEVLQ 1264



 Score = 27.7 bits (60), Expect = 9.3
 Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 15/99 (15%)

Query: 138  KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLK---TELRKT 194
            K Q E+  K  K    E EK+    K+H       + AE KKL  + ++L    ++L K 
Sbjct: 1208 KGQLEDLEKMLKV---EQEKMLLENKNHE-----TVAAEYKKLCGENDRLNHTYSQLLKE 1259

Query: 195  SDALSKAQNDVMEM----KMQSERLSKEYDQLLKEHSEL 229
            ++ L     ++  +    K++  RL  E+ +L +++ +L
Sbjct: 1260 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQL 1298


>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
          Length = 636

 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 36/115 (31%), Positives = 54/115 (46%), Gaps = 13/115 (11%)

Query: 120 LVTLITQLAKELSN-KGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC------- 171
           L TL  QL KE    K  L    E  ++AA++  EEN +LK++L S+G  E         
Sbjct: 208 LQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSP 267

Query: 172 VLEAENKKLVEDQEKLKTELRKTSD--ALSKAQNDVMEMKMQSERL---SKEYDQ 221
            +E   KK V  Q++      K  +  AL  A+  V  ++ Q   L   +K++DQ
Sbjct: 268 KMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQ 322


>gi|58530840 desmoplakin isoform I [Homo sapiens]
          Length = 2871

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/120 (23%), Positives = 59/120 (49%), Gaps = 3/120 (2%)

Query: 117  LRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAE 176
            L+     IT L ++L    ++K ++E+  +  +  ++ + + K+  +   +     +EA 
Sbjct: 1605 LKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEAL 1664

Query: 177  NKKLVEDQEKLK-TELRKT--SDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRL 233
             ++L+++QE +K   LR      A+      + E K++ ERL    + L KEH  L++ L
Sbjct: 1665 RRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEEL 1724



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 26/110 (23%), Positives = 59/110 (53%), Gaps = 13/110 (11%)

Query: 126  QLAKELSNKGVLKTQA-----ENTNKAAKKFMEEN---EKLKRILKSHGKDEECVLEAEN 177
            QL  EL     ++T+      ++ + AAK   ++N   E+LK+++     D +C LE EN
Sbjct: 1446 QLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC-LEDEN 1504

Query: 178  KKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHS 227
             +L    ++++ +L+K + + ++  N +   + +  RL  +Y+++ +E +
Sbjct: 1505 ARL----QRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERT 1550



 Score = 36.2 bits (82), Expect = 0.026
 Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 9/101 (8%)

Query: 137  LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQE--KLKTELRKT 194
            LK   +      K   +EN +L+R+     K      E  NK  V++QE  +L+ +  + 
Sbjct: 1486 LKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERV 1545

Query: 195  SDA-------LSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
            S         +++ QN + E+++Q +++ +E ++L +  SE
Sbjct: 1546 SQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASE 1586



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 15/50 (30%), Positives = 28/50 (56%)

Query: 173  LEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQL 222
            L  EN+ L E+ ++LK  L +T++ L + + D+ + K     +S+   QL
Sbjct: 1398 LTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQL 1447



 Score = 32.7 bits (73), Expect = 0.29
 Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 13/115 (11%)

Query: 130  ELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEE-------CVLEAENKKLVE 182
            E  N G  K ++E   KA K+   E E+L+ +L+  G  +         V    N+++  
Sbjct: 1149 EKENLGWQKLESE---KAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSN 1205

Query: 183  DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGN 237
             + K +TE+  T   + +     M+ +  S+ L  + D+L +E+ +L+D + R N
Sbjct: 1206 LRNKYETEINITKTTIKEIS---MQKEDDSKNLRNQLDRLSRENRDLKDEIVRLN 1257



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 24/102 (23%), Positives = 47/102 (46%), Gaps = 3/102 (2%)

Query: 137  LKTQAENTNKAAKKFMEENEKLKRILKSHG-KDEECVLEAENKKLVEDQEKLKTELRKTS 195
            LK  A   +   KK  EE E ++R LK    K      + E   +V+  ++ + +LR+  
Sbjct: 1580 LKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVK--KRSEDDLRQQR 1637

Query: 196  DALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGN 237
            D L     +    + +  RLS E + L ++  + Q+ +++ +
Sbjct: 1638 DVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAH 1679


>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
          Length = 1711

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/118 (23%), Positives = 63/118 (53%), Gaps = 1/118 (0%)

Query: 117 LRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAE 176
           +++L   I +L  ++++   L+ Q E+T    ++  +  ++L+ + K H    +   E  
Sbjct: 487 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQ-EKEEL 545

Query: 177 NKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLE 234
           +K+LVE  E+LK++ ++  DA  + +  + E    +ER+++   Q  K   +L+D+ E
Sbjct: 546 HKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEE 603



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 142 ENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKA 201
           +   K+ ++   E E+    +K   + E  +L  ENKKL  + EKL + + K +     A
Sbjct: 738 DKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLT-----A 792

Query: 202 QNDVMEMKMQSERLSKE 218
           QN  +E ++Q     KE
Sbjct: 793 QNRQLEDELQDLAAKKE 809


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 5/101 (4%)

Query: 140 QAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAEN-----KKLVEDQEKLKTELRKT 194
           Q E   +   K  E+ EK++R  K   + E+ + E E      KKL E +E+++ +  K 
Sbjct: 260 QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319

Query: 195 SDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLER 235
            +   K +    +M  Q ERL ++  Q+ ++  +++D+ ER
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 12/135 (8%)

Query: 117 LRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAE 176
           LR     + +  KEL  +  L+ Q E   +  +K  E+ EK++   +   + EE + E E
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344

Query: 177 NKKLVEDQEKLKTE----------LRKTSDALSKAQND-VMEMKMQSERLSKEYDQLLKE 225
            K++ E ++K++ +          LR+  + + + +     E KMQ E   +E ++ ++E
Sbjct: 345 -KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403

Query: 226 HSELQDRLERGNKKR 240
             E     E   +K+
Sbjct: 404 EEETMREQEEKMQKQ 418



 Score = 35.8 bits (81), Expect = 0.034
 Identities = 19/100 (19%), Positives = 54/100 (54%), Gaps = 1/100 (1%)

Query: 137 LKTQAENTNKAAKKFMEENEKL-KRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTS 195
           ++ Q E   +  +K  E+ EK+ ++  K   ++EE  ++ + + + E +EK++ +  K  
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649

Query: 196 DALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLER 235
           +   K +    +M+ Q E++  + +++ ++  ++Q + E+
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689



 Score = 35.0 bits (79), Expect = 0.058
 Identities = 20/99 (20%), Positives = 51/99 (51%), Gaps = 6/99 (6%)

Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
           ++ Q E   +  +K  E+ EK++   +   + EE + E E +  +++QE++  E  +   
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE--- 639

Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLER 235
              K Q    +M  Q E++ ++ +++ ++  ++Q + E+
Sbjct: 640 ---KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675



 Score = 34.3 bits (77), Expect = 0.099
 Identities = 21/96 (21%), Positives = 49/96 (51%), Gaps = 6/96 (6%)

Query: 140 QAENTNKAAKKFMEENEKLK-----RILKSHGKDEECVLEAENKKLVEDQEKLKTELRKT 194
           + + T +  KK  ++ EK++     R  +   ++EE ++  + +K+ E +EK++ +  K 
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597

Query: 195 SDALSKAQNDVMEMKMQSERL-SKEYDQLLKEHSEL 229
            +   K Q    +M  Q E++  +E +  ++E  E+
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633



 Score = 34.3 bits (77), Expect = 0.099
 Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 1/92 (1%)

Query: 138 KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDA 197
           K + E   +  +K M E E++ R  +   +++E  +  + +K+ E +EK++ +  K  + 
Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614

Query: 198 LSKAQNDVMEMKMQ-SERLSKEYDQLLKEHSE 228
             K      E KMQ  E +  E ++ ++E  E
Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 18/83 (21%), Positives = 43/83 (51%), Gaps = 1/83 (1%)

Query: 150 KFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMK 209
           KF+    +   + +   + EE + E E KK+ + +EK+  +  +  +   K +    +M+
Sbjct: 221 KFLLPQVQTNTLQEEMWRQEEELREQE-KKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279

Query: 210 MQSERLSKEYDQLLKEHSELQDR 232
            Q +RL ++  +L ++  EL+++
Sbjct: 280 RQEKRLREQEKELREQEKELREQ 302



 Score = 28.9 bits (63), Expect = 4.2
 Identities = 17/91 (18%), Positives = 47/91 (51%), Gaps = 4/91 (4%)

Query: 152 MEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQ 211
           M+E E+++   K   ++EE + E E K   +++   + E ++        Q    E   +
Sbjct: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK---EKLWE 444

Query: 212 SERLSKEYDQLLKEHSELQDRLER-GNKKRL 241
            E++ ++ +++ ++  +++D+ E  G +K++
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475



 Score = 28.9 bits (63), Expect = 4.2
 Identities = 18/89 (20%), Positives = 44/89 (49%), Gaps = 6/89 (6%)

Query: 153 EENEKLKRILKSHGKDEECVLEAENK------KLVEDQEKLKTELRKTSDALSKAQNDVM 206
           EE +K++   +   + EE + E E K      K+ E +EK++ +  K      K +    
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681

Query: 207 EMKMQSERLSKEYDQLLKEHSELQDRLER 235
           +M+ Q E++ ++ +++  +  ++  + E+
Sbjct: 682 KMQGQEEKMREQEEKMRGQEEKMWGQEEK 710



 Score = 28.5 bits (62), Expect = 5.5
 Identities = 21/110 (19%), Positives = 51/110 (46%), Gaps = 1/110 (0%)

Query: 130 ELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKT 189
           E   +  ++ Q E   +  +K  E+ EK+    +   + EE + E E +K+   +EK++ 
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE-EKMQGQEEKMRE 678

Query: 190 ELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKK 239
           +  K      K +    +M+ Q E++  + +++  +  ++  + E   K+
Sbjct: 679 QEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 26/98 (26%), Positives = 54/98 (55%), Gaps = 1/98 (1%)

Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
           L    E  +KA ++++E+  +L++ L +  +D++C LE +N+ L     +L+  L +  D
Sbjct: 341 LNELTEEHSKATQEWLEKQAQLEKELSAALQDKKC-LEEKNEILQGKLSQLEEHLSQLQD 399

Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLE 234
              + + +V+   +Q E L +E   L   +++LQ R+E
Sbjct: 400 NPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVE 437



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 18/96 (18%), Positives = 50/96 (52%), Gaps = 5/96 (5%)

Query: 138  KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDA 197
            + Q +   + +KK + ++++  ++ +   K     ++A+  +  ++ ++L+ +L +    
Sbjct: 1545 REQTKQVEELSKK-LADSDQASKVQQQKLK----AVQAQGGESQQEAQRLQAQLNELQAQ 1599

Query: 198  LSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRL 233
            LS+ +      K+Q E+    YD   +++ ELQ++L
Sbjct: 1600 LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQL 1635



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 5/69 (7%)

Query: 173 LEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDR 232
           L+A  + L   +  L+ E R+ +DAL + Q  + E+K ++  L +++    +E  EL++ 
Sbjct: 704 LQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK---RERKELEE- 759

Query: 233 LERGNKKRL 241
            ER  +K L
Sbjct: 760 -ERAGRKGL 767



 Score = 31.2 bits (69), Expect = 0.84
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 16/122 (13%)

Query: 118  RRLVTLITQLAKELSNKGV------LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC 171
            +RL   + +L  +LS K        L+ +   T+  AKK  ++N++L+  L+S  +    
Sbjct: 1587 QRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKK--QQNQELQEQLRSLEQ---- 1640

Query: 172  VLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEY---DQLLKEHSE 228
             L+ ENK+L  + E+L  EL++      +A+     +  Q   L  +    DQ L++  +
Sbjct: 1641 -LQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1699

Query: 229  LQ 230
             Q
Sbjct: 1700 FQ 1701



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 27/127 (21%), Positives = 60/127 (47%), Gaps = 6/127 (4%)

Query: 118 RRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAEN 177
           ++L +LIT L   +SN    K + E  ++A    +         L S        ++ ++
Sbjct: 462 QQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQ---VASLTSELTTLNATIQQQD 518

Query: 178 KKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLS---KEYDQLLKEHSELQDRLE 234
           ++L   +++ K +  + +  L + +     ++ Q E+LS   K+ +Q LKE +E Q+   
Sbjct: 519 QELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 578

Query: 235 RGNKKRL 241
           + + ++L
Sbjct: 579 QDHAQQL 585



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 3/113 (2%)

Query: 122 TLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLV 181
           +L  +L + L     LKT+    ++   +  EEN  L   L+      + + +A N+   
Sbjct: 287 SLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTE 346

Query: 182 EDQEKLKTELRKTSD---ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
           E  +  +  L K +     LS A  D   ++ ++E L  +  QL +  S+LQD
Sbjct: 347 EHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQD 399


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)

Query: 116  VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
            +L+  +  + +  +  +   +L+ Q E   + A++  E+ E++ + L    +  +  LEA
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370

Query: 176  ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
            E ++ +E   + E+LK  + + S A ++A+ D    + Q+E + ++
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 137  LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
            LKT+AE    A K+   ENE+L+R+ +        + E   +   + +E+L  +LRK SD
Sbjct: 1848 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1903

Query: 197  ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
            +  + Q  ++E  ++  R  +E    LK   E
Sbjct: 1904 SELERQKGLVEDTLRQRRQVEEEILALKASFE 1935



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 19/121 (15%)

Query: 126  QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
            +L KE   +   + QAE       +AA   ME+++K  ++ L+   + E+ +        
Sbjct: 2137 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2196

Query: 174  EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
            E +++K + D+E  +LK E  + +   S+ + ++  +++Q E LSK     LK   E ++
Sbjct: 2197 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK-----LKARIEAEN 2251

Query: 232  R 232
            R
Sbjct: 2252 R 2252



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 21/120 (17%), Positives = 60/120 (50%), Gaps = 5/120 (4%)

Query: 124  ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
            + +L  ++     L+ +AE   ++A++     E  ++ L++  K     ++ + ++L   
Sbjct: 2011 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2068

Query: 181  VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            ++ ++ +  +LR  ++A  +A  +  E ++Q+ER + +  + ++E   L+   E   + R
Sbjct: 2069 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2128


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)

Query: 116  VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
            +L+  +  + +  +  +   +L+ Q E   + A++  E+ E++ + L    +  +  LEA
Sbjct: 2315 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2374

Query: 176  ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
            E ++ +E   + E+LK  + + S A ++A+ D    + Q+E + ++
Sbjct: 2375 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2420



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 137  LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
            LKT+AE    A K+   ENE+L+R+ +        + E   +   + +E+L  +LRK SD
Sbjct: 1852 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1907

Query: 197  ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
            +  + Q  ++E  ++  R  +E    LK   E
Sbjct: 1908 SELERQKGLVEDTLRQRRQVEEEILALKASFE 1939



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 19/121 (15%)

Query: 126  QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
            +L KE   +   + QAE       +AA   ME+++K  ++ L+   + E+ +        
Sbjct: 2141 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2200

Query: 174  EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
            E +++K + D+E  +LK E  + +   S+ + ++  +++Q E LSK     LK   E ++
Sbjct: 2201 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK-----LKARIEAEN 2255

Query: 232  R 232
            R
Sbjct: 2256 R 2256



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 21/120 (17%), Positives = 60/120 (50%), Gaps = 5/120 (4%)

Query: 124  ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
            + +L  ++     L+ +AE   ++A++     E  ++ L++  K     ++ + ++L   
Sbjct: 2015 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2072

Query: 181  VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            ++ ++ +  +LR  ++A  +A  +  E ++Q+ER + +  + ++E   L+   E   + R
Sbjct: 2073 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2132


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)

Query: 116  VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
            +L+  +  + +  +  +   +L+ Q E   + A++  E+ E++ + L    +  +  LEA
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370

Query: 176  ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
            E ++ +E   + E+LK  + + S A ++A+ D    + Q+E + ++
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 137  LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
            LKT+AE    A K+   ENE+L+R+ +        + E   +   + +E+L  +LRK SD
Sbjct: 1848 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1903

Query: 197  ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
            +  + Q  ++E  ++  R  +E    LK   E
Sbjct: 1904 SELERQKGLVEDTLRQRRQVEEEILALKASFE 1935



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 19/121 (15%)

Query: 126  QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
            +L KE   +   + QAE       +AA   ME+++K  ++ L+   + E+ +        
Sbjct: 2137 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2196

Query: 174  EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
            E +++K + D+E  +LK E  + +   S+ + ++  +++Q E LSK     LK   E ++
Sbjct: 2197 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK-----LKARIEAEN 2251

Query: 232  R 232
            R
Sbjct: 2252 R 2252



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 21/120 (17%), Positives = 60/120 (50%), Gaps = 5/120 (4%)

Query: 124  ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
            + +L  ++     L+ +AE   ++A++     E  ++ L++  K     ++ + ++L   
Sbjct: 2011 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2068

Query: 181  VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            ++ ++ +  +LR  ++A  +A  +  E ++Q+ER + +  + ++E   L+   E   + R
Sbjct: 2069 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2128


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)

Query: 116  VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
            +L+  +  + +  +  +   +L+ Q E   + A++  E+ E++ + L    +  +  LEA
Sbjct: 2279 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2338

Query: 176  ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
            E ++ +E   + E+LK  + + S A ++A+ D    + Q+E + ++
Sbjct: 2339 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2384



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 137  LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
            LKT+AE    A K+   ENE+L+R+ +        + E   +   + +E+L  +LRK SD
Sbjct: 1816 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1871

Query: 197  ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
            +  + Q  ++E  ++  R  +E    LK   E
Sbjct: 1872 SELERQKGLVEDTLRQRRQVEEEILALKASFE 1903



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 19/121 (15%)

Query: 126  QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
            +L KE   +   + QAE       +AA   ME+++K  ++ L+   + E+ +        
Sbjct: 2105 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2164

Query: 174  EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
            E +++K + D+E  +LK E  + +   S+ + ++  +++Q E LSK     LK   E ++
Sbjct: 2165 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK-----LKARIEAEN 2219

Query: 232  R 232
            R
Sbjct: 2220 R 2220



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 21/120 (17%), Positives = 60/120 (50%), Gaps = 5/120 (4%)

Query: 124  ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
            + +L  ++     L+ +AE   ++A++     E  ++ L++  K     ++ + ++L   
Sbjct: 1979 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2036

Query: 181  VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            ++ ++ +  +LR  ++A  +A  +  E ++Q+ER + +  + ++E   L+   E   + R
Sbjct: 2037 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2096


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)

Query: 116  VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
            +L+  +  + +  +  +   +L+ Q E   + A++  E+ E++ + L    +  +  LEA
Sbjct: 2448 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2507

Query: 176  ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
            E ++ +E   + E+LK  + + S A ++A+ D    + Q+E + ++
Sbjct: 2508 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2553



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 137  LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
            LKT+AE    A K+   ENE+L+R+ +        + E   +   + +E+L  +LRK SD
Sbjct: 1985 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 2040

Query: 197  ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
            +  + Q  ++E  ++  R  +E    LK   E
Sbjct: 2041 SELERQKGLVEDTLRQRRQVEEEILALKASFE 2072



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 19/121 (15%)

Query: 126  QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
            +L KE   +   + QAE       +AA   ME+++K  ++ L+   + E+ +        
Sbjct: 2274 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2333

Query: 174  EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
            E +++K + D+E  +LK E  + +   S+ + ++  +++Q E LSK     LK   E ++
Sbjct: 2334 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK-----LKARIEAEN 2388

Query: 232  R 232
            R
Sbjct: 2389 R 2389



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 21/120 (17%), Positives = 60/120 (50%), Gaps = 5/120 (4%)

Query: 124  ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
            + +L  ++     L+ +AE   ++A++     E  ++ L++  K     ++ + ++L   
Sbjct: 2148 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2205

Query: 181  VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            ++ ++ +  +LR  ++A  +A  +  E ++Q+ER + +  + ++E   L+   E   + R
Sbjct: 2206 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2265


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)

Query: 116  VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
            +L+  +  + +  +  +   +L+ Q E   + A++  E+ E++ + L    +  +  LEA
Sbjct: 2289 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2348

Query: 176  ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
            E ++ +E   + E+LK  + + S A ++A+ D    + Q+E + ++
Sbjct: 2349 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2394



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 137  LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
            LKT+AE    A K+   ENE+L+R+ +        + E   +   + +E+L  +LRK SD
Sbjct: 1826 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1881

Query: 197  ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
            +  + Q  ++E  ++  R  +E    LK   E
Sbjct: 1882 SELERQKGLVEDTLRQRRQVEEEILALKASFE 1913



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 19/121 (15%)

Query: 126  QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
            +L KE   +   + QAE       +AA   ME+++K  ++ L+   + E+ +        
Sbjct: 2115 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2174

Query: 174  EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQD 231
            E +++K + D+E  +LK E  + +   S+ + ++  +++Q E LSK     LK   E ++
Sbjct: 2175 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK-----LKARIEAEN 2229

Query: 232  R 232
            R
Sbjct: 2230 R 2230



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 21/120 (17%), Positives = 60/120 (50%), Gaps = 5/120 (4%)

Query: 124  ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
            + +L  ++     L+ +AE   ++A++     E  ++ L++  K     ++ + ++L   
Sbjct: 1989 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2046

Query: 181  VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQDRLERGNKKR 240
            ++ ++ +  +LR  ++A  +A  +  E ++Q+ER + +  + ++E   L+   E   + R
Sbjct: 2047 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2106


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,674,091
Number of Sequences: 37866
Number of extensions: 283029
Number of successful extensions: 4039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 241
Number of HSP's successfully gapped in prelim test: 469
Number of HSP's that attempted gapping in prelim test: 2483
Number of HSP's gapped (non-prelim): 1891
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.