Guide to the Human Genome
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Search of human proteins with 134288915

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
         (1314 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|134288915 myosin IIIB isoform 1 [Homo sapiens]                    2659   0.0  
gi|134288892 myosin IIIB isoform 2 [Homo sapiens]                    2645   0.0  
gi|145275208 myosin IIIA [Homo sapiens]                              1452   0.0  
gi|122937512 myosin VIIB [Homo sapiens]                               503   e-142
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     495   e-139
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     495   e-139
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     495   e-139
gi|118402590 myosin XV [Homo sapiens]                                 472   e-133
gi|154354979 myosin X [Homo sapiens]                                  467   e-131
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                   443   e-124
gi|153945715 myosin VC [Homo sapiens]                                 430   e-120
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       421   e-117
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       421   e-117
gi|156119615 myosin IXA [Homo sapiens]                                415   e-115
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]    415   e-115
gi|122937345 myosin VB [Homo sapiens]                                 413   e-115
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...   407   e-113
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...   407   e-113
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]   404   e-112
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...   404   e-112
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...   404   e-112
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                      403   e-112
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                       403   e-112
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...   402   e-111
gi|156104908 myosin heavy chain 6 [Homo sapiens]                      399   e-111
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]          399   e-110
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...   398   e-110
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...   397   e-110
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...   397   e-110
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]          397   e-110

>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
          Length = 1314

 Score = 2659 bits (6893), Expect = 0.0
 Identities = 1314/1314 (100%), Positives = 1314/1314 (100%)

Query: 1    MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDP 60
            MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDP
Sbjct: 1    MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDP 60

Query: 61   VSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKG 120
            VSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKG
Sbjct: 61   VSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKG 120

Query: 121  LLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQ 180
            LLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQ
Sbjct: 121  LLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQ 180

Query: 181  LTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMH 240
            LTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMH
Sbjct: 181  LTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMH 240

Query: 241  PVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKV 300
            PVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKV
Sbjct: 241  PVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKV 300

Query: 301  LFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTII 360
            LFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTII
Sbjct: 301  LFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTII 360

Query: 361  HQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAY 420
            HQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAY
Sbjct: 361  HQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAY 420

Query: 421  QCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGN 480
            QCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGN
Sbjct: 421  QCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGN 480

Query: 481  SCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAG 540
            SCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAG
Sbjct: 481  SCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAG 540

Query: 541  LHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVH 600
            LHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVH
Sbjct: 541  LHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVH 600

Query: 601  SVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCV 660
            SVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCV
Sbjct: 601  SVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCV 660

Query: 661  VTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGI 720
            VTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGI
Sbjct: 661  VTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGI 720

Query: 721  LDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPL 780
            LDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPL
Sbjct: 721  LDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPL 780

Query: 781  LDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGK 840
            LDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGK
Sbjct: 781  LDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGK 840

Query: 841  VLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSL 900
            VLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSL
Sbjct: 841  VLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSL 900

Query: 901  PPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN 960
            PPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN
Sbjct: 901  PPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN 960

Query: 961  DDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLAS 1020
            DDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLAS
Sbjct: 961  DDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLAS 1020

Query: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRY 1080
            KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRY
Sbjct: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRY 1080

Query: 1081 KKVREKREKGAIAIQSGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRGSVHRRS 1140
            KKVREKREKGAIAIQSGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRGSVHRRS
Sbjct: 1081 KKVREKREKGAIAIQSGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRGSVHRRS 1140

Query: 1141 HSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSPKGCDIFAGHANKHSVSGTDLLSSRICH 1200
            HSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSPKGCDIFAGHANKHSVSGTDLLSSRICH
Sbjct: 1141 HSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSPKGCDIFAGHANKHSVSGTDLLSSRICH 1200

Query: 1201 PAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRRCQQPKMLSSPEDTMYYNQLNGTLEYQG 1260
            PAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRRCQQPKMLSSPEDTMYYNQLNGTLEYQG
Sbjct: 1201 PAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRRCQQPKMLSSPEDTMYYNQLNGTLEYQG 1260

Query: 1261 SKRKPRKLGQIKVLDGEDEYYKSLSPVDCIPEENNSAHPSFFSSSSKGDSFAQH 1314
            SKRKPRKLGQIKVLDGEDEYYKSLSPVDCIPEENNSAHPSFFSSSSKGDSFAQH
Sbjct: 1261 SKRKPRKLGQIKVLDGEDEYYKSLSPVDCIPEENNSAHPSFFSSSSKGDSFAQH 1314


>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
          Length = 1341

 Score = 2645 bits (6855), Expect = 0.0
 Identities = 1314/1341 (97%), Positives = 1314/1341 (97%), Gaps = 27/1341 (2%)

Query: 1    MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDP 60
            MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDP
Sbjct: 1    MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDP 60

Query: 61   VSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKG 120
            VSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKG
Sbjct: 61   VSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKG 120

Query: 121  LLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQ 180
            LLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQ
Sbjct: 121  LLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQ 180

Query: 181  LTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMH 240
            LTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMH
Sbjct: 181  LTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMH 240

Query: 241  PVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKV 300
            PVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKV
Sbjct: 241  PVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKV 300

Query: 301  LFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTII 360
            LFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTII
Sbjct: 301  LFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTII 360

Query: 361  HQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAY 420
            HQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAY
Sbjct: 361  HQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAY 420

Query: 421  QCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGN 480
            QCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGN
Sbjct: 421  QCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGN 480

Query: 481  SCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAG 540
            SCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAG
Sbjct: 481  SCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAG 540

Query: 541  LHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVH 600
            LHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVH
Sbjct: 541  LHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVH 600

Query: 601  SVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCV 660
            SVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCV
Sbjct: 601  SVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCV 660

Query: 661  VTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGI 720
            VTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGI
Sbjct: 661  VTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGI 720

Query: 721  LDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPL 780
            LDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPL
Sbjct: 721  LDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPL 780

Query: 781  LDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGK 840
            LDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGK
Sbjct: 781  LDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGK 840

Query: 841  VLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSL 900
            VLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSL
Sbjct: 841  VLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSL 900

Query: 901  PPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN 960
            PPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN
Sbjct: 901  PPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN 960

Query: 961  DDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLAS 1020
            DDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLAS
Sbjct: 961  DDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLAS 1020

Query: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRY 1080
            KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRY
Sbjct: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRY 1080

Query: 1081 KKVREKREKGAIAIQS---------------------------GDTSNQSSGPHSPVAAG 1113
            KKVREKREKGAIAIQS                           GDTSNQSSGPHSPVAAG
Sbjct: 1081 KKVREKREKGAIAIQSAWRGYDARRKFKKISNRRNESAAHNQAGDTSNQSSGPHSPVAAG 1140

Query: 1114 TRGSAEVQDCSEPGDHKVLRGSVHRRSHSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSP 1173
            TRGSAEVQDCSEPGDHKVLRGSVHRRSHSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSP
Sbjct: 1141 TRGSAEVQDCSEPGDHKVLRGSVHRRSHSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSP 1200

Query: 1174 KGCDIFAGHANKHSVSGTDLLSSRICHPAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRR 1233
            KGCDIFAGHANKHSVSGTDLLSSRICHPAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRR
Sbjct: 1201 KGCDIFAGHANKHSVSGTDLLSSRICHPAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRR 1260

Query: 1234 CQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPVDCIPEE 1293
            CQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPVDCIPEE
Sbjct: 1261 CQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPVDCIPEE 1320

Query: 1294 NNSAHPSFFSSSSKGDSFAQH 1314
            NNSAHPSFFSSSSKGDSFAQH
Sbjct: 1321 NNSAHPSFFSSSSKGDSFAQH 1341


>gi|145275208 myosin IIIA [Homo sapiens]
          Length = 1616

 Score = 1452 bits (3759), Expect = 0.0
 Identities = 709/1080 (65%), Positives = 870/1080 (80%), Gaps = 1/1080 (0%)

Query: 18   ESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQF 77
            ++ PDP+DTWEI ETIGKGTYGKV+KV NK++G  AAVKILDP+ D+DEEIEAEYNIL+ 
Sbjct: 12   DNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKA 71

Query: 78   LPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYIL 137
            L +HPNVV+FYG+++K D   G +LWLVLELC+GGSVT+LVKG L+ G+R+ E +I+YIL
Sbjct: 72   LSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYIL 131

Query: 138  YGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFW 197
            + AL+GLQHLHNN+ IHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTR RRNTSVGTPFW
Sbjct: 132  HEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFW 191

Query: 198  MAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLL 257
            MAPEVIACEQQ D++YDARCD WSLGITAIELGDGDPPL D+HP++ LFKIPRNPPP L 
Sbjct: 192  MAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLR 251

Query: 258  HPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLAKVLQDQKHQ 317
             PE W  EFN FIS+CL KD+E+RP+V+ LL H FI  + GK + LQKQL + +   +  
Sbjct: 252  QPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFIGIHQCM 311

Query: 318  NPVAKTRHERMHTRRPYHVEDAEKYCLE-DDLVNLEVLDEDTIIHQLQKRYADLLIYTYV 376
                K R ER+HT++            + DDL  LE+LDE+T+  QL+K Y+   IY YV
Sbjct: 312  GGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYV 371

Query: 377  GDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISG 436
            GDILIALNPFQ+L +YS + S+LY G KR ++PPHIFA AD  YQ M+T + DQCIVISG
Sbjct: 372  GDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISG 431

Query: 437  ESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYL 496
            ESG+GKTE+AHL+VQ LT LGKANN+TL+EKILQVN+LVEAFGN+CT INDNSSRFGKYL
Sbjct: 432  ESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYL 491

Query: 497  EMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEK 556
            EM FT +G V+GA+ISEYLLEKSRVI QA  EKNFHIFYYIYAGL  +KKL+ ++LPE K
Sbjct: 492  EMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENK 551

Query: 557  PPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIE 616
            PPRY+ ++  R + DI +   Y+ Q+E I+ CF++IGFT +++ S+Y ILA ILN+GNIE
Sbjct: 552  PPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIE 611

Query: 617  FAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRA 676
            F++++++HQ DKS + N  AL+N AS+LCI  +ELQEALTSHCVVTRGETIIR NTV++A
Sbjct: 612  FSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKA 671

Query: 677  ADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQ 736
             DVRDAM+K LYGRLFSWIVN IN+LL+ D +    G  +++GILDIFGFENF++NSFEQ
Sbjct: 672  TDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQ 731

Query: 737  LCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLD 796
            LCINIANEQIQYY+NQHVFA EQ EY NE +DA  +EYEDN PLLDMFLQKP+GLL+LLD
Sbjct: 732  LCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLD 791

Query: 797  EESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTL 856
            EESRFP+ATDQTLV+KFE NL+ +YFWRPK +EL FGI HYAGKVLY+ASG L KNRDTL
Sbjct: 792  EESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTL 851

Query: 857  PADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEV 916
            P D+V++LR+S+N +++QL + PLTKTGNL  ++ +  +             AK DT E 
Sbjct: 852  PTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEA 911

Query: 917  IRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQ 976
             RH  ETTNMK QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN +R+A ++ +E+VL Q
Sbjct: 912  TRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQ 971

Query: 977  LRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLDHW 1036
            LR TGILET  IRR G+SHRILF  F+KRYY L + + + P  S ++C  ILEK+ LD+W
Sbjct: 972  LRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLDNW 1031

Query: 1037 VLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQS 1096
             LGKTKVFLKYYHVEQLNL+ +E I +++++QA  + +L +RRY+K++EKR++ AI IQS
Sbjct: 1032 ALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQS 1091



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 30/66 (45%), Positives = 43/66 (65%), Gaps = 2/66 (3%)

Query: 1230 PRRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPVDC 1289
            P RR ++PK L++PED+ YY  L+ ++  Q  KR+PRK  Q K+LD ED YYK   P   
Sbjct: 1492 PPRRPRKPKTLNNPEDSTYYYLLHKSI--QEEKRRPRKDSQGKLLDLEDFYYKEFLPSRS 1549

Query: 1290 IPEENN 1295
             P+E++
Sbjct: 1550 GPKEHS 1555


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score =  503 bits (1294), Expect = e-142
 Identities = 298/770 (38%), Positives = 448/770 (58%), Gaps = 61/770 (7%)

Query: 346  DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405
            DD++ L  L+E  ++H L  RY    IYTY G IL+A+NPFQ L +Y+ +  +LY+    
Sbjct: 68   DDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHM 127

Query: 406  ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLR 465
               PPH+FA A+  Y  M    +DQC +ISGESG+GKTE+  LI+Q L  +    +  + 
Sbjct: 128  GELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS-GQHSWIE 186

Query: 466  EKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQA 525
            +++L+ N ++EAFGN+ T  NDNSSRFGKY+++ F P+GV+ GARI ++LLEKSRV +QA
Sbjct: 187  QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQA 246

Query: 526  AREKNFHIFYYIYAGLHHQ-KKLSDFRLPEEKPPRYIADETGRVMHDITSKESYR--RQF 582
              E+N+HIFY +  G+  + K+L     P E    Y+       M + TS E     + +
Sbjct: 247  PEERNYHIFYCMLMGVSAEDKQLLSLGTPSEY--HYLT------MGNCTSCEGLNDAKDY 298

Query: 583  EAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAAS 642
              I+   +I+ F+D E   V ++LA IL++GN+ F A S     D S+V    A      
Sbjct: 299  AHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMA-SVFENLDASDVMETPAFPTVMK 357

Query: 643  VLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTL 702
            +L +  +EL++ L  H ++ RGE + R+  + +AAD RDA  K +YG LF WIV +IN  
Sbjct: 358  LLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAA 417

Query: 703  L-----QPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFAL 757
            +     Q  +N+  A     +G+LDIFGFENF+ NSFEQLCIN ANE +Q +F QHVF +
Sbjct: 418  IFTPPAQDPKNVRRA-----IGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTM 472

Query: 758  EQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFED-N 816
            EQ EY++E I    + Y DNRP LD+   KP+ +++LLDEESRFPQ TD T++ K    +
Sbjct: 473  EQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVH 532

Query: 817  LRCKYFWRPKGV-ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQL 875
               K F +PK + +  FGI H+AG+V Y A G LEKNRD L  D++ ++ +S+N  L+++
Sbjct: 533  ANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREI 592

Query: 876  FSIPLTKT----GNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTV 931
            F++ L +T    G + Q +A   +  S+                        +N +  T+
Sbjct: 593  FNLELAETKLGHGTIRQAKAGNHLFKSA-----------------------DSNKRPSTL 629

Query: 932  ASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQ 991
             S F+ SL  L+  +   QP+F+RCIKPN+ ++ L F RE  L QLR +G++ETV IR+ 
Sbjct: 630  GSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKS 689

Query: 992  GYSHRILFEEFVKRYYYLAFTAHQTPLASK--ESCVAILEK-SRLD-HWVLGKTKVFLKY 1047
            G+  R  FEEF +R+  L   A +  L  K  +  + I +   R D  W  GKTK+FL+ 
Sbjct: 690  GFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRD 749

Query: 1048 YHVEQLNLLLREVIGRVVV-LQAYTKGWLGARRYKKVREKREKGAIAIQS 1096
            +    L +   +V+ R  + +Q   +G+    RY+K   ++ + A+ +Q+
Sbjct: 750  HQDTLLEVQRSQVLDRAALSIQKVLRGY----RYRKEFLRQRRAAVTLQA 795


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  495 bits (1274), Expect = e-139
 Identities = 294/785 (37%), Positives = 436/785 (55%), Gaps = 62/785 (7%)

Query: 309  KVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYA 368
            +V+ D+ +++ ++      +    P  V   E      D++ L  L+E  I+  L  RY 
Sbjct: 37   QVVDDEDNEHWISPQNATHIKPMHPTSVHGVE------DMIRLGDLNEAGILRNLLIRYR 90

Query: 369  DLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSK 428
            D LIYTY G IL+A+NP+Q LSIYSP+  R Y   K    PPHIFA AD  Y  M   S+
Sbjct: 91   DHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSR 150

Query: 429  DQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDN 488
            DQC +ISGESG+GKTES  LI+Q L  +    +  + +++L+   ++EAFGN+ T  NDN
Sbjct: 151  DQCCIISGESGAGKTESTKLILQFLAAIS-GQHSWIEQQVLEATPILEAFGNAKTIRNDN 209

Query: 489  SSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLS 548
            SSRFGKY+++ F   G + GA+I +YLLEKSRV +QA  E+N+H+FY +  G+   +K  
Sbjct: 210  SSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQK-K 268

Query: 549  DFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAG 608
               L +     Y+A             + Y      I+   +++ FTD E   + ++LA 
Sbjct: 269  KLGLGQASDYNYLAMGNCITCEGRVDSQEYAN----IRSAMKVLMFTDTENWEISKLLAA 324

Query: 609  ILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETII 668
            IL++GN+++ A + ++  D  EV  + +L  AAS+L ++P +L   LTS  ++TRGET+ 
Sbjct: 325  ILHLGNLQYEARTFEN-LDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVS 383

Query: 669  RANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFEN 728
               + ++A DVRDA  K +YGRLF WIV++IN  +    +        ++G+LDIFGFEN
Sbjct: 384  TPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFEN 443

Query: 729  FQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKP 788
            F  NSFEQLCIN ANE +Q +F +HVF LEQ EY  E ID + +E+ DN+  LDM   KP
Sbjct: 444  FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKP 503

Query: 789  LGLLALLDEESRFPQATDQTLVDKF--EDNLRCKYFWRPKGVELCFGIQHYAGKVLYDAS 846
            + +++L+DEES+FP+ TD T++ K   +  L   Y       E  FGI H+AG V Y+  
Sbjct: 504  MNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQ 563

Query: 847  GVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSA 906
            G LEKNRDTL  D++ ++ +S N  ++Q+F   +      A+TR R              
Sbjct: 564  GFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG---AETRKR-------------- 606

Query: 907  GKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREAL 966
                                   T++S F+ SL  L+  +   QP FVRCIKPN+ ++ +
Sbjct: 607  ---------------------SPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPM 645

Query: 967  QFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYL------AFTAHQTPLAS 1020
             F R   + QLR +G++ET+ IRR GY  R  F EFV+RY  L      A+         
Sbjct: 646  LFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTC 705

Query: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLL-REVIGRVVVLQAYTKGWLGARR 1079
            +    A+L     D W +GKTK+FLK +H   L +   + +  RV++LQ   +G+     
Sbjct: 706  QRMAEAVL--GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSN 763

Query: 1080 YKKVR 1084
            + K++
Sbjct: 764  FLKLK 768


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  495 bits (1274), Expect = e-139
 Identities = 294/785 (37%), Positives = 436/785 (55%), Gaps = 62/785 (7%)

Query: 309  KVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYA 368
            +V+ D+ +++ ++      +    P  V   E      D++ L  L+E  I+  L  RY 
Sbjct: 37   QVVDDEDNEHWISPQNATHIKPMHPTSVHGVE------DMIRLGDLNEAGILRNLLIRYR 90

Query: 369  DLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSK 428
            D LIYTY G IL+A+NP+Q LSIYSP+  R Y   K    PPHIFA AD  Y  M   S+
Sbjct: 91   DHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSR 150

Query: 429  DQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDN 488
            DQC +ISGESG+GKTES  LI+Q L  +    +  + +++L+   ++EAFGN+ T  NDN
Sbjct: 151  DQCCIISGESGAGKTESTKLILQFLAAIS-GQHSWIEQQVLEATPILEAFGNAKTIRNDN 209

Query: 489  SSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLS 548
            SSRFGKY+++ F   G + GA+I +YLLEKSRV +QA  E+N+H+FY +  G+   +K  
Sbjct: 210  SSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQK-K 268

Query: 549  DFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAG 608
               L +     Y+A             + Y      I+   +++ FTD E   + ++LA 
Sbjct: 269  KLGLGQASDYNYLAMGNCITCEGRVDSQEYAN----IRSAMKVLMFTDTENWEISKLLAA 324

Query: 609  ILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETII 668
            IL++GN+++ A + ++  D  EV  + +L  AAS+L ++P +L   LTS  ++TRGET+ 
Sbjct: 325  ILHLGNLQYEARTFEN-LDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVS 383

Query: 669  RANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFEN 728
               + ++A DVRDA  K +YGRLF WIV++IN  +    +        ++G+LDIFGFEN
Sbjct: 384  TPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFEN 443

Query: 729  FQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKP 788
            F  NSFEQLCIN ANE +Q +F +HVF LEQ EY  E ID + +E+ DN+  LDM   KP
Sbjct: 444  FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKP 503

Query: 789  LGLLALLDEESRFPQATDQTLVDKF--EDNLRCKYFWRPKGVELCFGIQHYAGKVLYDAS 846
            + +++L+DEES+FP+ TD T++ K   +  L   Y       E  FGI H+AG V Y+  
Sbjct: 504  MNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQ 563

Query: 847  GVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSA 906
            G LEKNRDTL  D++ ++ +S N  ++Q+F   +      A+TR R              
Sbjct: 564  GFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG---AETRKR-------------- 606

Query: 907  GKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREAL 966
                                   T++S F+ SL  L+  +   QP FVRCIKPN+ ++ +
Sbjct: 607  ---------------------SPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPM 645

Query: 967  QFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYL------AFTAHQTPLAS 1020
             F R   + QLR +G++ET+ IRR GY  R  F EFV+RY  L      A+         
Sbjct: 646  LFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTC 705

Query: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLL-REVIGRVVVLQAYTKGWLGARR 1079
            +    A+L     D W +GKTK+FLK +H   L +   + +  RV++LQ   +G+     
Sbjct: 706  QRMAEAVL--GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSN 763

Query: 1080 YKKVR 1084
            + K++
Sbjct: 764  FLKLK 768


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  495 bits (1274), Expect = e-139
 Identities = 294/785 (37%), Positives = 436/785 (55%), Gaps = 62/785 (7%)

Query: 309  KVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYA 368
            +V+ D+ +++ ++      +    P  V   E      D++ L  L+E  I+  L  RY 
Sbjct: 37   QVVDDEDNEHWISPQNATHIKPMHPTSVHGVE------DMIRLGDLNEAGILRNLLIRYR 90

Query: 369  DLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSK 428
            D LIYTY G IL+A+NP+Q LSIYSP+  R Y   K    PPHIFA AD  Y  M   S+
Sbjct: 91   DHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSR 150

Query: 429  DQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDN 488
            DQC +ISGESG+GKTES  LI+Q L  +    +  + +++L+   ++EAFGN+ T  NDN
Sbjct: 151  DQCCIISGESGAGKTESTKLILQFLAAIS-GQHSWIEQQVLEATPILEAFGNAKTIRNDN 209

Query: 489  SSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLS 548
            SSRFGKY+++ F   G + GA+I +YLLEKSRV +QA  E+N+H+FY +  G+   +K  
Sbjct: 210  SSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQK-K 268

Query: 549  DFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAG 608
               L +     Y+A             + Y      I+   +++ FTD E   + ++LA 
Sbjct: 269  KLGLGQASDYNYLAMGNCITCEGRVDSQEYAN----IRSAMKVLMFTDTENWEISKLLAA 324

Query: 609  ILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETII 668
            IL++GN+++ A + ++  D  EV  + +L  AAS+L ++P +L   LTS  ++TRGET+ 
Sbjct: 325  ILHLGNLQYEARTFEN-LDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVS 383

Query: 669  RANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFEN 728
               + ++A DVRDA  K +YGRLF WIV++IN  +    +        ++G+LDIFGFEN
Sbjct: 384  TPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFEN 443

Query: 729  FQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKP 788
            F  NSFEQLCIN ANE +Q +F +HVF LEQ EY  E ID + +E+ DN+  LDM   KP
Sbjct: 444  FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKP 503

Query: 789  LGLLALLDEESRFPQATDQTLVDKF--EDNLRCKYFWRPKGVELCFGIQHYAGKVLYDAS 846
            + +++L+DEES+FP+ TD T++ K   +  L   Y       E  FGI H+AG V Y+  
Sbjct: 504  MNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQ 563

Query: 847  GVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSA 906
            G LEKNRDTL  D++ ++ +S N  ++Q+F   +      A+TR R              
Sbjct: 564  GFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMG---AETRKR-------------- 606

Query: 907  GKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREAL 966
                                   T++S F+ SL  L+  +   QP FVRCIKPN+ ++ +
Sbjct: 607  ---------------------SPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPM 645

Query: 967  QFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYL------AFTAHQTPLAS 1020
             F R   + QLR +G++ET+ IRR GY  R  F EFV+RY  L      A+         
Sbjct: 646  LFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTC 705

Query: 1021 KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLL-REVIGRVVVLQAYTKGWLGARR 1079
            +    A+L     D W +GKTK+FLK +H   L +   + +  RV++LQ   +G+     
Sbjct: 706  QRMAEAVL--GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSN 763

Query: 1080 YKKVR 1084
            + K++
Sbjct: 764  FLKLK 768


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score =  472 bits (1215), Expect = e-133
 Identities = 295/784 (37%), Positives = 442/784 (56%), Gaps = 76/784 (9%)

Query: 332  RPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSI 391
            R  H ED       +D+  LE L E T++  L+ R+   LIYTY+G IL+++NP+Q   I
Sbjct: 1216 REQHGEDGV-----EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGI 1270

Query: 392  YSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQ 451
            Y P+  + Y+G     NPPH+FA A+ A+  M+   ++QCI+ISGESGSGKTE+  LI++
Sbjct: 1271 YGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILR 1330

Query: 452  HLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARI 511
            +L  + +      + KIL+   L+E+FGN+ T  NDNSSRFGK++E +F   GV+ GA  
Sbjct: 1331 YLAAMNQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVE-IFLEGGVISGAIT 1389

Query: 512  SEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHD 571
            S+YLLEKSR++ QA  E+N+HIFY + AGL  Q + + F L E +   Y+       +  
Sbjct: 1390 SQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQA-FSLQEAETYYYLNQGGNCEIAG 1448

Query: 572  ITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEV 631
             +  + +RR   A++    ++GF+ ++  S++RILA IL++GN+ F     +++TD  EV
Sbjct: 1449 KSDADDFRRLLAAME----VLGFSSEDQDSIFRILASILHLGNVYF----EKYETDAQEV 1500

Query: 632  P---NAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALY 688
                +A  +Q  A +L ISPE LQ+A+T     T  E I    TV+ A D RDA++K LY
Sbjct: 1501 ASVVSAREIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLY 1560

Query: 689  GRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQY 748
              LFSW++ R+N L+ P ++       +++ ILDI+GFE+   NSFEQLCIN ANE +QY
Sbjct: 1561 ALLFSWLITRVNALVSPRQDT------LSIAILDIYGFEDLSFNSFEQLCINYANENLQY 1614

Query: 749  YFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQT 808
             FN+ VF  EQ EY  E ID   + + DN+P +++   KP G+L +LD++  FPQATD T
Sbjct: 1615 LFNKIVFQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHT 1674

Query: 809  LVDKFEDNLRCKY-------FWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVV 861
             + K      C Y       + +PK     F I+HYAGKV Y     L+KN D +  DV+
Sbjct: 1675 FLQK------CHYHHGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVL 1728

Query: 862  VVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPE 921
             +   S   ++  LFS       +  Q   +    SSS+                     
Sbjct: 1729 DLFVRSRTRVVAHLFS------SHAPQAAPQRLGKSSSV--------------------- 1761

Query: 922  ETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTG 981
             T   K  TVA+ F+ SL+DL+ KM    P F+RC+KPN  +E   F  + V+AQLR +G
Sbjct: 1762 -TRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSG 1820

Query: 982  ILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILE---KSRLDHWVL 1038
            +LETV IR++G+  R+ F+ F+ RY  L    H  P A+ + CV++L    K   + + +
Sbjct: 1821 VLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLP-ANGDMCVSVLSRLCKVMPNMYRV 1879

Query: 1039 GKTKVFLKYYHVEQLNLLLREVIG-RVVVLQAYTKGWLGARRYKKVREK------REKGA 1091
            G +K+FLK +  + L  +   V+    + LQ   +G+   RR++ +R K      R +G 
Sbjct: 1880 GVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHKIILLQSRARGY 1939

Query: 1092 IAIQ 1095
            +A Q
Sbjct: 1940 LARQ 1943


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  467 bits (1202), Expect = e-131
 Identities = 289/772 (37%), Positives = 443/772 (57%), Gaps = 70/772 (9%)

Query: 325  HERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALN 384
            H+++    P + E        DD+ +L  L   +I++ L +RY    IYTY+G IL ++N
Sbjct: 51   HQKVTAMHPTNEEGV------DDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVN 104

Query: 385  PFQNLS-IYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKT 443
            P+Q ++ +Y P     Y        PPHIFA A+  Y+C+     +QCI+ISGESG+GKT
Sbjct: 105  PYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKT 164

Query: 444  ESAHLIVQHLTFLGKANNQ-TLREK-------ILQVNSLVEAFGNSCTAINDNSSRFGKY 495
            ES  LI++ L+ + + + + +L+EK       IL+ + ++EAFGN+ T  N+NSSRFGK+
Sbjct: 165  ESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224

Query: 496  LEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEE 555
            +++     G + G RI +YLLEK+RV++Q   E+N+HIFY + AGL H+++  +F L   
Sbjct: 225  VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEER-EEFYLSTP 283

Query: 556  KPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNI 615
            +   Y+          I+ +ES+R    A+     ++ F+ +EV  V R+LAGIL++GNI
Sbjct: 284  ENYHYLNQSGCVEDKTISDQESFREVITAMD----VMQFSKEEVREVSRLLAGILHLGNI 339

Query: 616  EFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDR 675
            EF           ++V    AL  +A +L + P +L +ALT   +  RGE I+    V +
Sbjct: 340  EFITAGG------AQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQ 393

Query: 676  AADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFE 735
            A D RD+++ ALY   F W++ +IN+ ++ +E+  S      +GILDIFGFENF+ N FE
Sbjct: 394  AVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKS------IGILDIFGFENFEVNHFE 447

Query: 736  QLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALL 795
            Q  IN ANE++Q YFN+H+F+LEQ+EY  EG+    +++ DN   LD+ ++K LGLLAL+
Sbjct: 448  QFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDL-IEKKLGLLALI 506

Query: 796  DEESRFPQATDQTLVDKFEDNLRCKYFW-RPKGVELCFGIQHYAGKVLYDASGVLEKNRD 854
            +EES FPQATD TL++K        +F+ +P+     FG++HYAG+V YD  G+LEKNRD
Sbjct: 507  NEESHFPQATDSTLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRD 566

Query: 855  TLPADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTL 914
            T   D++ +LR S    +  LF                          H S+ +   DTL
Sbjct: 567  TFRDDLLNLLRESRFDFIYDLFE-------------------------HVSS-RNNQDTL 600

Query: 915  EVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVL 974
            +        +  +R TV+S F+ SL  L++ +    P FVRCIKPN  +   QF +  VL
Sbjct: 601  KC------GSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVL 654

Query: 975  AQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILE--KSR 1032
             QLR +G+LETV IR+ GY+ R  F++F KRY  L       P   +  C ++L+   + 
Sbjct: 655  NQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL-ALPEDVRGKCTSLLQLYDAS 713

Query: 1033 LDHWVLGKTKVFLKYYHVEQLNLLLREVIGR-VVVLQAYTKGWLGARRYKKV 1083
               W LGKTKVFL+    ++L     E +    +V++A+  G+L  ++Y+KV
Sbjct: 714  NSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKV 765


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score =  443 bits (1139), Expect = e-124
 Identities = 266/786 (33%), Positives = 439/786 (55%), Gaps = 41/786 (5%)

Query: 346  DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYH---G 402
            DDL  L  L++ ++++++QKR+ +  IYT++GDIL+ +NP++ L IYS   S+LY    G
Sbjct: 404  DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463

Query: 403  VKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQ 462
               +S PPH+F+  + A+  +    + QC ++SGE GSGK+E++  I++HLT    A+  
Sbjct: 464  KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523

Query: 463  TLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTP-TGVVMGARISEYLLEKSRV 521
            TL  +   V  ++EAFG++ T +ND SS F KY E+ F      + GARI  YLLEKSR+
Sbjct: 524  TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583

Query: 522  IKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQ 581
            + Q   + NF IFY +  GL  ++K     L      RY+ ++T +       +   R +
Sbjct: 584  VSQPLGQSNFLIFYLLMDGLSAEEKYG-LHLNNLCAHRYL-NQTIQDDASTGERSLNREK 641

Query: 582  FEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAA 641
               ++    ++GF+  EV +++ ILA IL++G+I F A+   ++ + + V + + L+  A
Sbjct: 642  LAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTAL---NEGNSAFVSDLQLLEQVA 698

Query: 642  SVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINT 701
             +L +S +EL  ALT+     +G+ IIR +T+  A   RD ++K+LY RLFS++VN +N+
Sbjct: 699  GMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNS 758

Query: 702  LLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQME 761
             L   +   S    +++GILDIFGFE FQ+N FEQLC+N+ NE++ +Y N+ +F  EQ+E
Sbjct: 759  CLHSQDEQKSM-QTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVE 817

Query: 762  YQNEGIDAVPVEYEDNR-PLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFE---DNL 817
               EG+         N+  +LD F QKP G L LLDEES+   + +     K +   ++ 
Sbjct: 818  CVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESS 877

Query: 818  RCKYFWRP----------KGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTS 867
                 + P          K     F I HYAG+V+YD  G +EKN+D+L  +++ V++TS
Sbjct: 878  NTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTS 937

Query: 868  ENMLLQQLFSIPLTKTGNLAQT---------RARITVASSSLPPHFSAGKAKVDTLEVIR 918
            EN+++  LF   L++TG+L            ++ +     +        K  ++  ++++
Sbjct: 938  ENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLK 997

Query: 919  HPEETTNMKR------QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRER 972
                +T ++R       T+AS  R SLMD++ K+    PHF+ CI+PN+ +    F    
Sbjct: 998  KKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFY 1057

Query: 973  VLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLA--FTAHQTPLASKESCVAILEK 1030
            V AQL+  G+LE V I R GY  R+ F +F+ RY  LA  F   +   ++ E C  +L++
Sbjct: 1058 VSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQ 1117

Query: 1031 SRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKG 1090
             +L  W +G  KVFLKY+H +QLN L  ++  +++  Q   +G+L  +   +    R++ 
Sbjct: 1118 CKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQE 1177

Query: 1091 AIAIQS 1096
              +I S
Sbjct: 1178 VTSINS 1183


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  430 bits (1105), Expect = e-120
 Identities = 271/758 (35%), Positives = 406/758 (53%), Gaps = 46/758 (6%)

Query: 345  EDDLVNLEVLDEDTIIHQLQKRYADL-LIYTYVGDILIALNPFQNLSIYSPQFSRLYHGV 403
            E+DL  L  L E  ++H L+ R+A+  LIYTY G IL+A+NP++ L IY       Y G 
Sbjct: 69   ENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQ 128

Query: 404  KRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKA-NNQ 462
                  PHIFA A+ AY+ M   +++Q I++SGESG+GKT SA   +++   + K+ +N 
Sbjct: 129  NMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNA 188

Query: 463  TLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVI 522
             + +K+L  N + EA GN+ T  NDNSSRFGKY E+ F     ++GA +S YLLEKSRV+
Sbjct: 189  HVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVV 248

Query: 523  KQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQF 582
             Q+  E+N+HIFY + A    Q +    +L   +   Y       V+  +      R + 
Sbjct: 249  FQSENERNYHIFYQLCASA-QQSEFKHLKLGSAEEFNYTRMGGNTVIEGVND----RAEM 303

Query: 583  EAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAAS 642
               Q  F ++GF +     V++ILA IL++GN++  A+ ++  +   +  +   L+    
Sbjct: 304  VETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSH---LKVFCE 360

Query: 643  VLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTL 702
            +L +    + + L +  +VT  ET+++  T  +A + RDA++K +Y  LF +IV RIN  
Sbjct: 361  LLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQA 420

Query: 703  LQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEY 762
            LQ      S      +G+LDI+GFE F  NSFEQ CIN ANE++Q  FN HVF LEQ EY
Sbjct: 421  LQ-----FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEY 475

Query: 763  QNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNL--RCK 820
              E I    +++ DN+P++D+ ++  +G+L LLDEE   P  TD+  + K  +N   R  
Sbjct: 476  MKEDIPWTLIDFYDNQPVIDL-IEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNP 534

Query: 821  YFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPL 880
             F +P+     F IQH+A KV Y   G LEKNRDT+   +V +LR S+  L    F    
Sbjct: 535  LFEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQ--- 591

Query: 881  TKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLM 940
                             +  PP        V + + +  P   +   R TV S FR SL 
Sbjct: 592  ----------------ENPTPPSPFGSMITVKSAKQVIKP--NSKHFRTTVGSKFRSSLY 633

Query: 941  DLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFE 1000
             L+  +    PH+VRCIKPND++   +F  +R++ QLR+ G+LET+ I  Q Y  R  + 
Sbjct: 634  LLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYI 693

Query: 1001 EFVKRYYYLAFTAHQTPLASKESCVAILEKSRLD--HWVLGKTKVFLKYYHVEQL-NLLL 1057
            EF  RY  L      +    KE C  +L +   D   +  GKTK+F +   V  L  L L
Sbjct: 694  EFYSRYGILMTKQELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRL 753

Query: 1058 REVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQ 1095
             ++    V++Q + +GWL  +R K +RE+R   A+ IQ
Sbjct: 754  DKLRQSCVMVQKHMRGWL--QRKKFLRERR--AALIIQ 787


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  421 bits (1083), Expect = e-117
 Identities = 284/812 (34%), Positives = 427/812 (52%), Gaps = 65/812 (8%)

Query: 299  KVLFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDT 358
            KVL L  +  K L+   H +P  K   E  H R P      +    E+DL  L  L E  
Sbjct: 36   KVLLLHLEEGKDLE--YHLDPKTK---ELPHLRNP------DILVGENDLTALSYLHEPA 84

Query: 359  IIHQLQKRYADL-LIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASAD 417
            ++H L+ R+ D  LIYTY G +L+A+NP++ L IY       Y G       PHIFA A+
Sbjct: 85   VLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAE 144

Query: 418  AAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHL-TFLGKANNQTLREKILQVNSLVE 476
             AY+ M    ++Q I++SGESG+GKT SA   +++  T  G A+   + EK+L  N ++E
Sbjct: 145  EAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIME 204

Query: 477  AFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYY 536
            + GN+ T  NDNSSRFGKY+E+ F     ++GA +  YLLEKSRV+ QA  E+N+HIFY 
Sbjct: 205  SIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQ 264

Query: 537  IYAGLHHQKKLSDF---RLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIG 593
            + A      KL +F   RL       Y       V+  +   +      +A      ++G
Sbjct: 265  LCA----SAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQAC----TLLG 316

Query: 594  FTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQE 653
             ++     ++RILAGIL++GN+ F   +S+     +  P  E L     ++ +  EE+  
Sbjct: 317  ISESHQMGIFRILAGILHLGNVGF---TSRDADSCTIPPKHEPLCIFCDLMGVDYEEMCH 373

Query: 654  ALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAG 713
             L    + T  ET I+  +  +A + RDA++K +Y +LF+WIV+ +N  L       S  
Sbjct: 374  WLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSF- 432

Query: 714  GGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVE 773
                +G+LDI+GFE F+ NSFEQ CIN ANE++Q  FN HVF LEQ EY  E I    ++
Sbjct: 433  ----IGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLID 488

Query: 774  YEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDN--LRCKYFWRPKGVELC 831
            + DN+P +++ ++  LG+L LLDEE + P+ TD T   K  +    +C  F +P+     
Sbjct: 489  FYDNQPCINL-IESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKA 547

Query: 832  FGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLF---SIPLTKTGNLAQ 888
            F IQH+A KV Y   G LEKN+DT+  + + VL++S+  +L +LF      ++ T   + 
Sbjct: 548  FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSS 607

Query: 889  TRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVV 948
             R  +T      P   + G+           P +     ++TV   FR SL  L+  +  
Sbjct: 608  GRTPLT----RTPAKPTKGR-----------PGQMAKEHKKTVGHQFRNSLHLLMETLNA 652

Query: 949  GQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYY 1008
              PH+VRCIKPND +    F  +R + QLR+ G+LET+ I   G+  R  ++EF  RY  
Sbjct: 653  TTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRV 712

Query: 1009 LAFTAHQTPLAS--KESCVAILEKSRL--DHWVLGKTKVFLKYYHVEQLNLLLREVIGRV 1064
            L     Q  + S  K++C  +LEK  L  D +  GKTK+F +   V  L  L  + +   
Sbjct: 713  L---MKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAA 769

Query: 1065 VV-LQAYTKGWLGARRYKKVREKREKGAIAIQ 1095
             + +Q   +GWL  ++Y ++R    K AI +Q
Sbjct: 770  CIRIQKTIRGWLLRKKYLRMR----KAAITMQ 797


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  421 bits (1083), Expect = e-117
 Identities = 284/812 (34%), Positives = 427/812 (52%), Gaps = 65/812 (8%)

Query: 299  KVLFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDT 358
            KVL L  +  K L+   H +P  K   E  H R P      +    E+DL  L  L E  
Sbjct: 36   KVLLLHLEEGKDLE--YHLDPKTK---ELPHLRNP------DILVGENDLTALSYLHEPA 84

Query: 359  IIHQLQKRYADL-LIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASAD 417
            ++H L+ R+ D  LIYTY G +L+A+NP++ L IY       Y G       PHIFA A+
Sbjct: 85   VLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAE 144

Query: 418  AAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHL-TFLGKANNQTLREKILQVNSLVE 476
             AY+ M    ++Q I++SGESG+GKT SA   +++  T  G A+   + EK+L  N ++E
Sbjct: 145  EAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIME 204

Query: 477  AFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYY 536
            + GN+ T  NDNSSRFGKY+E+ F     ++GA +  YLLEKSRV+ QA  E+N+HIFY 
Sbjct: 205  SIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQ 264

Query: 537  IYAGLHHQKKLSDF---RLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIG 593
            + A      KL +F   RL       Y       V+  +   +      +A      ++G
Sbjct: 265  LCA----SAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQAC----TLLG 316

Query: 594  FTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQE 653
             ++     ++RILAGIL++GN+ F   +S+     +  P  E L     ++ +  EE+  
Sbjct: 317  ISESHQMGIFRILAGILHLGNVGF---TSRDADSCTIPPKHEPLCIFCDLMGVDYEEMCH 373

Query: 654  ALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAG 713
             L    + T  ET I+  +  +A + RDA++K +Y +LF+WIV+ +N  L       S  
Sbjct: 374  WLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSF- 432

Query: 714  GGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVE 773
                +G+LDI+GFE F+ NSFEQ CIN ANE++Q  FN HVF LEQ EY  E I    ++
Sbjct: 433  ----IGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLID 488

Query: 774  YEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDN--LRCKYFWRPKGVELC 831
            + DN+P +++ ++  LG+L LLDEE + P+ TD T   K  +    +C  F +P+     
Sbjct: 489  FYDNQPCINL-IESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKA 547

Query: 832  FGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLF---SIPLTKTGNLAQ 888
            F IQH+A KV Y   G LEKN+DT+  + + VL++S+  +L +LF      ++ T   + 
Sbjct: 548  FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSS 607

Query: 889  TRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVV 948
             R  +T      P   + G+           P +     ++TV   FR SL  L+  +  
Sbjct: 608  GRTPLT----RTPAKPTKGR-----------PGQMAKEHKKTVGHQFRNSLHLLMETLNA 652

Query: 949  GQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYY 1008
              PH+VRCIKPND +    F  +R + QLR+ G+LET+ I   G+  R  ++EF  RY  
Sbjct: 653  TTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRV 712

Query: 1009 LAFTAHQTPLAS--KESCVAILEKSRL--DHWVLGKTKVFLKYYHVEQLNLLLREVIGRV 1064
            L     Q  + S  K++C  +LEK  L  D +  GKTK+F +   V  L  L  + +   
Sbjct: 713  L---MKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAA 769

Query: 1065 VV-LQAYTKGWLGARRYKKVREKREKGAIAIQ 1095
             + +Q   +GWL  ++Y ++R    K AI +Q
Sbjct: 770  CIRIQKTIRGWLLRKKYLRMR----KAAITMQ 797


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score =  415 bits (1067), Expect = e-115
 Identities = 229/552 (41%), Positives = 333/552 (60%), Gaps = 25/552 (4%)

Query: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405
           DDL +L  L+E T++  L+ R+    IYTYVG ILI +NPF+ L IY+P++ ++Y   + 
Sbjct: 149 DDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQL 208

Query: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464
               PHI+A AD AY  M+   K+QCIVISGESGSGKT+S + ++ HLT L  K     +
Sbjct: 209 GKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGV 268

Query: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524
            + IL    ++EAFGN+ TA N+NSSRFGK++++ +  TG V+GA + +YLLEKSR++ Q
Sbjct: 269 EQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQ 328

Query: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHD------------- 571
              E+N+H+FYY+ AG    ++ S F L + +   Y+   T + +               
Sbjct: 329 EHNERNYHVFYYLLAGASEDER-SAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDC 387

Query: 572 -ITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSE 630
                E  R  FE +Q    ++GF  K    ++ +L+ IL++GNI +      ++ D  +
Sbjct: 388 FTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYK--KKTYRDDSID 445

Query: 631 VPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGR 690
           + N E L   + +L +  E L EAL +   VT GE +I    +  A  VR++M+K+LY  
Sbjct: 446 ICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSA 505

Query: 691 LFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYF 750
           LF WIV RIN  L   +++      +++G+LDIFGFE+++ NSFEQ CIN ANE++Q+YF
Sbjct: 506 LFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYF 565

Query: 751 NQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLV 810
           NQH+F LEQ EY+ EGI    ++Y DN   +++  +KP GLL LLDEES FPQAT+QTL+
Sbjct: 566 NQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLL 625

Query: 811 DKF----EDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRT 866
           DKF    EDN    Y   P  +E  F I+HYAGKV Y      EKN D +  D+V +LR+
Sbjct: 626 DKFKHQHEDN---SYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRS 682

Query: 867 SENMLLQQLFSI 878
           S+N  +  +  I
Sbjct: 683 SKNAFISGMIGI 694



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 56/162 (34%), Positives = 96/162 (59%), Gaps = 6/162 (3%)

Query: 927  KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986
            K  ++++ F+ SL  L+  +   +P+FV+CI+ N ++  L+FS   VL QLR TG+LETV
Sbjct: 886  KPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETV 945

Query: 987  SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRL--DHWVLGKTKVF 1044
             IR+ GYS +  F++FV  ++ L     +  + SK +      K  L  D++ +GKT VF
Sbjct: 946  RIRQSGYSSKYSFQDFVSHFHVL---LPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVF 1002

Query: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVRE 1085
            LK    + L +LL +EV+ R+++LQ + +  L  + +  +R+
Sbjct: 1003 LKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQ 1044


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score =  415 bits (1066), Expect = e-115
 Identities = 263/771 (34%), Positives = 425/771 (55%), Gaps = 69/771 (8%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            K+   +D+  L  L+E +++H L++RY   LIYTY G   + +NP++NL IYS +   +Y
Sbjct: 79   KFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMY 138

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFL---- 456
             G KR   PPHI+A  D AY+ M+   +DQ I+ +GESG+GKTE+   ++Q+L ++    
Sbjct: 139  KGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSH 198

Query: 457  -GKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYL 515
              K +   L  ++LQ N ++EAFGN+ T  NDNSSRFGK++ + F   G ++GA I  YL
Sbjct: 199  KSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYL 258

Query: 516  LEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSK 575
            LEKSR I+QA  E+ FHIFYY+ +G     K +D  L      R++++      H     
Sbjct: 259  LEKSRAIRQAKEERTFHIFYYLLSGAGEHLK-TDLLLEPYNKYRFLSNG-----HVTIPG 312

Query: 576  ESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAE 635
            +  +  F+      RI+G  ++E   + R+++G+L +GNI F     +  TD++ +P+  
Sbjct: 313  QQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVF---KKERNTDQASMPDNT 369

Query: 636  ALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWI 695
            A Q  + +L I+  +    + +  +    + + +A T ++A    +A++KA Y R+F W+
Sbjct: 370  AAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWL 429

Query: 696  VNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVF 755
            V RIN  L   +      G   +GILDI GFE F  NSFEQLCIN  NE++Q  FN  +F
Sbjct: 430  VLRINKALDKTKR----QGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMF 485

Query: 756  ALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQKPL---GLLALLDEESRFPQATDQTLVD 811
             LEQ EYQ EGI+   +++  D +P +D+ ++KP    G+LALLDEE  FP+ATD++ V+
Sbjct: 486  ILEQEEYQREGIEWNFIDFGLDLQPCIDL-IEKPAGPPGILALLDEECWFPKATDKSFVE 544

Query: 812  K-FEDNLRCKYFWRPKGV--ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSE 868
            K  ++      F +PK +  +  F I HYAGKV Y A   L KN D L  ++  +L  S 
Sbjct: 545  KVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSS 604

Query: 869  NMLLQQLFS-----IPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEET 923
            +  + +L+      I L +   +++T         +LP  F   K               
Sbjct: 605  DKFVSELWKDVDRIIGLDQVAGMSET---------ALPGAFKTRKGMF------------ 643

Query: 924  TNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGIL 983
                 +TV   ++  L  L++ +    P+FVRCI PN +++A +     VL QLR  G+L
Sbjct: 644  -----RTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVL 698

Query: 984  ETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTP---LASKESCVAILEKSRLDH--WVL 1038
            E + I RQG+ +R++F+EF +RY  L  T +  P   +  K++CV +++   LD   + +
Sbjct: 699  EGIRICRQGFPNRVVFQEFRQRYEIL--TPNSIPKGFMDGKQACVLMIKALELDSNLYRI 756

Query: 1039 GKTKVFLK---YYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREK 1086
            G++KVF +     H+E+   L  ++   ++  QA  +G+L  + + K +++
Sbjct: 757  GQSKVFFRAGVLAHLEEERDL--KITDVIIGFQACCRGYLARKAFAKRQQQ 805


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  413 bits (1061), Expect = e-115
 Identities = 264/762 (34%), Positives = 409/762 (53%), Gaps = 57/762 (7%)

Query: 345  EDDLVNLEVLDEDTIIHQLQKRYADLL-IYTYVGDILIALNPFQNLSIYSPQFSRLYHGV 403
            E+DL  L  L E  ++H L+ R+ +   IYTY G +L+A+NP++ L IY       Y G 
Sbjct: 71   ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130

Query: 404  KRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQT 463
                  PHIFA A+ AY+ M    K+Q I++SGESG+GKT SA   +++   +G + ++T
Sbjct: 131  NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190

Query: 464  -LREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVI 522
             + EK+L  + ++EA GN+ T  NDNSSRFGKY+++ F     ++GA +  YLLEKSRV+
Sbjct: 191  NIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVV 250

Query: 523  KQAAREKNFHIFYYIYA--GLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRR 580
             QA  E+N+HIFY + A  GL   K+L+   L   +   Y +      +  +   E    
Sbjct: 251  FQADDERNYHIFYQLCAAAGLPEFKELA---LTSAEDFFYTSQGGDTSIEGVDDAED--- 304

Query: 581  QFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEV-PNAEALQN 639
             FE  +  F ++G  +    S+++I+A IL++G++   AI ++   D   + P    L N
Sbjct: 305  -FEKTRQAFTLLGVKESHQMSIFKIIASILHLGSV---AIQAERDGDSCSISPQDVYLSN 360

Query: 640  AASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRI 699
               +L +   +++  L    +VT  ET ++  ++ +  + R+A++K +Y +LF WIV  I
Sbjct: 361  FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI 420

Query: 700  NTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQ 759
            N  L       S      +G+LDI+GFE F+ NSFEQ CIN ANE++Q  FN HVF LEQ
Sbjct: 421  NKALHTSLKQHSF-----IGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQ 475

Query: 760  MEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFED-NLR 818
             EY  E I    +++ DN+P +D+ ++  LG+L LLDEE + P+ TDQ    K  D +  
Sbjct: 476  EEYMKEQIPWTLIDFYDNQPCIDL-IEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSS 534

Query: 819  CKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLF-- 876
             ++F +P+     F I H+A KV Y + G LEKNRDT+  + + +L+ S+  L+  LF  
Sbjct: 535  SQHFQKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHD 594

Query: 877  ---SIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMK-RQTVA 932
                +P T  G    + ++I+V S+                   R P + +N + ++TV 
Sbjct: 595  DKDPVPATTPGK--GSSSKISVRSA-------------------RPPMKVSNKEHKKTVG 633

Query: 933  SYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQG 992
              FR SL  L+  +    PH+VRCIKPND++    F  +R + QLR+ G+LET+ I   G
Sbjct: 634  HQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAG 693

Query: 993  YSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEK--SRLDHWVLGKTKVFLKYYHV 1050
            Y  R  + +F  RY  L           K  C ++LE      D +  G+TK+F +   V
Sbjct: 694  YPSRWAYHDFFNRYRVLVKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQV 753

Query: 1051 EQLNLLLREVI-GRVVVLQAYTKGWLGARRYKKVREKREKGA 1091
              L  L  +      +++Q   +GWL     +KV+  R KGA
Sbjct: 754  AYLEKLRADKFRTATIMIQKTVRGWL-----QKVKYHRLKGA 790


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score =  407 bits (1046), Expect = e-113
 Identities = 270/767 (35%), Positives = 428/767 (55%), Gaps = 58/767 (7%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            K+   +D+  L  L+E +++H L++RY   LIYTY G   + +NP+++L IYS +   +Y
Sbjct: 83   KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKAN 460
             G KR   PPHI+A AD AY+ M+   +DQ I+ +GESG+GKTE+   ++Q+L  +  ++
Sbjct: 143  KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202

Query: 461  --------NQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARIS 512
                       L +++LQ N ++EAFGN+ T  NDNSSRFGK++ + F  TG ++GA I 
Sbjct: 203  KGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262

Query: 513  EYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDI 572
             YLLEKSR I+QA  E+ FHIFYY+ AG   +K  SD  L  E    Y     G V    
Sbjct: 263  TYLLEKSRAIRQARDERTFHIFYYMIAGA-KEKMRSDLLL--EGFNNYTFLSNGFVPIPA 319

Query: 573  TSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVP 632
               +     F+       I+GF+++E  S+ ++++ +L +GNI F     +  TD++ +P
Sbjct: 320  AQDD---EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVF---KKERNTDQASMP 373

Query: 633  NAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLF 692
            +  A Q    ++ I+  +   ++ +  +    + + +A T ++A    +A++KA Y RLF
Sbjct: 374  DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLF 433

Query: 693  SWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQ 752
             WI+ R+N  L          G   +GILDI GFE F+ NSFEQLCIN  NE++Q  FN 
Sbjct: 434  RWILTRVNKALDKTHR----QGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNH 489

Query: 753  HVFALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQ--KPLGLLALLDEESRFPQATDQTL 809
             +F LEQ EYQ EGI+   +++  D +P +++  +   P G+LALLDEE  FP+ATD++ 
Sbjct: 490  TMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSF 549

Query: 810  VDKF--EDNLRCKYFWRPKGV--ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLR 865
            V+K   E     K F +PK +  +  F I HYAGKV Y+AS  L KN D L  +V  +L 
Sbjct: 550  VEKLCTEQGSHPK-FQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLN 608

Query: 866  TSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTN 925
             S +  +  L+   + +   L Q  A++T   SSLP   SA K K               
Sbjct: 609  ASSDKFVADLWK-DVDRIVGLDQ-MAKMT--ESSLP---SASKTKKGMF----------- 650

Query: 926  MKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILET 985
               +TV   ++  L  L++ +    P+FVRCI PN ++ + +     VL QLR  G+LE 
Sbjct: 651  ---RTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEG 707

Query: 986  VSIRRQGYSHRILFEEFVKRYYYLAFTA-HQTPLASKESCVAILEKSRLDH--WVLGKTK 1042
            + I RQG+ +RI+F+EF +RY  LA  A  +  +  K++C+ +++   LD   + +G++K
Sbjct: 708  IRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSK 767

Query: 1043 VFLK---YYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREK 1086
            +F +     H+E+   L  ++   ++  QA  +G+L  + + K +++
Sbjct: 768  IFFRTGVLAHLEEERDL--KITDVIMAFQAMCRGYLARKAFAKRQQQ 812


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score =  407 bits (1046), Expect = e-113
 Identities = 270/767 (35%), Positives = 428/767 (55%), Gaps = 58/767 (7%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            K+   +D+  L  L+E +++H L++RY   LIYTY G   + +NP+++L IYS +   +Y
Sbjct: 83   KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKAN 460
             G KR   PPHI+A AD AY+ M+   +DQ I+ +GESG+GKTE+   ++Q+L  +  ++
Sbjct: 143  KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202

Query: 461  --------NQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARIS 512
                       L +++LQ N ++EAFGN+ T  NDNSSRFGK++ + F  TG ++GA I 
Sbjct: 203  KGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262

Query: 513  EYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDI 572
             YLLEKSR I+QA  E+ FHIFYY+ AG   +K  SD  L  E    Y     G V    
Sbjct: 263  TYLLEKSRAIRQARDERTFHIFYYMIAGA-KEKMRSDLLL--EGFNNYTFLSNGFVPIPA 319

Query: 573  TSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVP 632
               +     F+       I+GF+++E  S+ ++++ +L +GNI F     +  TD++ +P
Sbjct: 320  AQDD---EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVF---KKERNTDQASMP 373

Query: 633  NAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLF 692
            +  A Q    ++ I+  +   ++ +  +    + + +A T ++A    +A++KA Y RLF
Sbjct: 374  DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLF 433

Query: 693  SWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQ 752
             WI+ R+N  L          G   +GILDI GFE F+ NSFEQLCIN  NE++Q  FN 
Sbjct: 434  RWILTRVNKALDKTHR----QGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNH 489

Query: 753  HVFALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQ--KPLGLLALLDEESRFPQATDQTL 809
             +F LEQ EYQ EGI+   +++  D +P +++  +   P G+LALLDEE  FP+ATD++ 
Sbjct: 490  TMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSF 549

Query: 810  VDKF--EDNLRCKYFWRPKGV--ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLR 865
            V+K   E     K F +PK +  +  F I HYAGKV Y+AS  L KN D L  +V  +L 
Sbjct: 550  VEKLCTEQGSHPK-FQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLN 608

Query: 866  TSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTN 925
             S +  +  L+   + +   L Q  A++T   SSLP   SA K K               
Sbjct: 609  ASSDKFVADLWK-DVDRIVGLDQ-MAKMT--ESSLP---SASKTKKGMF----------- 650

Query: 926  MKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILET 985
               +TV   ++  L  L++ +    P+FVRCI PN ++ + +     VL QLR  G+LE 
Sbjct: 651  ---RTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEG 707

Query: 986  VSIRRQGYSHRILFEEFVKRYYYLAFTA-HQTPLASKESCVAILEKSRLDH--WVLGKTK 1042
            + I RQG+ +RI+F+EF +RY  LA  A  +  +  K++C+ +++   LD   + +G++K
Sbjct: 708  IRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSK 767

Query: 1043 VFLK---YYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREK 1086
            +F +     H+E+   L  ++   ++  QA  +G+L  + + K +++
Sbjct: 768  IFFRTGVLAHLEEERDL--KITDVIMAFQAMCRGYLARKAFAKRQQQ 812


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score =  404 bits (1039), Expect = e-112
 Identities = 263/769 (34%), Positives = 424/769 (55%), Gaps = 62/769 (8%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            K+   +D+  L  L+E +++H L+ RY   LIYTY G   + +NP++NL IYS     +Y
Sbjct: 83   KFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMY 142

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKAN 460
             G KR   PPHI+A +++AY+CM+   +DQ I+ +GESG+GKTE+   ++Q+L  +  ++
Sbjct: 143  RGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSH 202

Query: 461  N--------QTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARIS 512
                       L  ++LQ N ++E+FGN+ T  NDNSSRFGK++ + F  TG ++GA I 
Sbjct: 203  KGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262

Query: 513  EYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRV-MHD 571
             YLLEKSR ++QA  E+ FHIFY + +G     K SD  L      R++++  G + +  
Sbjct: 263  TYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLK-SDLLLEGFNNYRFLSN--GYIPIPG 319

Query: 572  ITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEV 631
               K++++   EA+     I+GF+ +E+ S+ ++++ +L  GNI F     +  TD++ +
Sbjct: 320  QQDKDNFQETMEAM----HIMGFSHEEILSMLKVVSSVLQFGNISF---KKERNTDQASM 372

Query: 632  PNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRL 691
            P     Q    +L ++  E   A+ +  +    + + +A T ++A    +A++KA Y RL
Sbjct: 373  PENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERL 432

Query: 692  FSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFN 751
            F W+V+RIN  L   +      G   +GILDI GFE F+ NSFEQLCIN  NE++Q  FN
Sbjct: 433  FRWLVHRINKALDRTKR----QGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFN 488

Query: 752  QHVFALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQ--KPLGLLALLDEESRFPQATDQT 808
              +F LEQ EYQ EGI+   +++  D +P +D+  +   P G+LALLDEE  FP+ATD+T
Sbjct: 489  HTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKT 548

Query: 809  LVDKF-EDNLRCKYFWRPKGV--ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLR 865
             V+K  ++      F +P+ +  +  F I HYAGKV Y A   L KN D L  +V  +L 
Sbjct: 549  FVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLH 608

Query: 866  TSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTN 925
             S +  + +L+   + +   L Q       A        SA K K               
Sbjct: 609  QSSDRFVAELWK-DVDRIVGLDQVTGMTETAFG------SAYKTKKGMF----------- 650

Query: 926  MKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILET 985
               +TV   ++ SL  L++ +    P+FVRCI PN ++ A +     VL QLR  G+LE 
Sbjct: 651  ---RTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEG 707

Query: 986  VSIRRQGYSHRILFEEFVKRYYYLAFTAHQTP---LASKESCVAILEKSRLDH--WVLGK 1040
            + I RQG+ +RI+F+EF +RY  L  T +  P   +  K++C  ++    LD   + +G+
Sbjct: 708  IRICRQGFPNRIVFQEFRQRYEIL--TPNAIPKGFMDGKQACERMIRALELDPNLYRIGQ 765

Query: 1041 TKVFLK---YYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREK 1086
            +K+F +     H+E+   L  ++   ++  QA  +G+L  + + K +++
Sbjct: 766  SKIFFRAGVLAHLEEERDL--KITDIIIFFQAVCRGYLARKAFAKKQQQ 812


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score =  404 bits (1039), Expect = e-112
 Identities = 270/774 (34%), Positives = 428/774 (55%), Gaps = 65/774 (8%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            K+   +D+  L  L+E +++H L++RY   LIYTY G   + +NP+++L IYS +   +Y
Sbjct: 83   KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKAN 460
             G KR   PPHI+A AD AY+ M+   +DQ I+ +GESG+GKTE+   ++Q+L  +  ++
Sbjct: 143  KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202

Query: 461  N---------------QTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGV 505
                              L +++LQ N ++EAFGN+ T  NDNSSRFGK++ + F  TG 
Sbjct: 203  KGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGY 262

Query: 506  VMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADET 565
            ++GA I  YLLEKSR I+QA  E+ FHIFYY+ AG   +K  SD  L  E    Y     
Sbjct: 263  IVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGA-KEKMRSDLLL--EGFNNYTFLSN 319

Query: 566  GRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQ 625
            G V       +     F+       I+GF+++E  S+ ++++ +L +GNI F     +  
Sbjct: 320  GFVPIPAAQDD---EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVF---KKERN 373

Query: 626  TDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSK 685
            TD++ +P+  A Q    ++ I+  +   ++ +  +    + + +A T ++A    +A++K
Sbjct: 374  TDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAK 433

Query: 686  ALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQ 745
            A Y RLF WI+ R+N  L          G   +GILDI GFE F+ NSFEQLCIN  NE+
Sbjct: 434  ATYERLFRWILTRVNKALDKTHR----QGASFLGILDIAGFEIFEVNSFEQLCINYTNEK 489

Query: 746  IQYYFNQHVFALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQ--KPLGLLALLDEESRFP 802
            +Q  FN  +F LEQ EYQ EGI+   +++  D +P +++  +   P G+LALLDEE  FP
Sbjct: 490  LQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP 549

Query: 803  QATDQTLVDKF--EDNLRCKYFWRPKGV--ELCFGIQHYAGKVLYDASGVLEKNRDTLPA 858
            +ATD++ V+K   E     K F +PK +  +  F I HYAGKV Y+AS  L KN D L  
Sbjct: 550  KATDKSFVEKLCTEQGSHPK-FQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLND 608

Query: 859  DVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIR 918
            +V  +L  S +  +  L+   + +   L Q  A++T   SSLP   SA K K        
Sbjct: 609  NVTSLLNASSDKFVADLWK-DVDRIVGLDQ-MAKMT--ESSLP---SASKTKKGMF---- 657

Query: 919  HPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLR 978
                      +TV   ++  L  L++ +    P+FVRCI PN ++ + +     VL QLR
Sbjct: 658  ----------RTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLR 707

Query: 979  STGILETVSIRRQGYSHRILFEEFVKRYYYLAFTA-HQTPLASKESCVAILEKSRLDH-- 1035
              G+LE + I RQG+ +RI+F+EF +RY  LA  A  +  +  K++C+ +++   LD   
Sbjct: 708  CNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNL 767

Query: 1036 WVLGKTKVFLK---YYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREK 1086
            + +G++K+F +     H+E+   L  ++   ++  QA  +G+L  + + K +++
Sbjct: 768  YRIGQSKIFFRTGVLAHLEEERDL--KITDVIMAFQAMCRGYLARKAFAKRQQQ 819


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score =  404 bits (1039), Expect = e-112
 Identities = 270/774 (34%), Positives = 428/774 (55%), Gaps = 65/774 (8%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            K+   +D+  L  L+E +++H L++RY   LIYTY G   + +NP+++L IYS +   +Y
Sbjct: 83   KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKAN 460
             G KR   PPHI+A AD AY+ M+   +DQ I+ +GESG+GKTE+   ++Q+L  +  ++
Sbjct: 143  KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202

Query: 461  N---------------QTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGV 505
                              L +++LQ N ++EAFGN+ T  NDNSSRFGK++ + F  TG 
Sbjct: 203  KGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGY 262

Query: 506  VMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADET 565
            ++GA I  YLLEKSR I+QA  E+ FHIFYY+ AG   +K  SD  L  E    Y     
Sbjct: 263  IVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGA-KEKMRSDLLL--EGFNNYTFLSN 319

Query: 566  GRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQ 625
            G V       +     F+       I+GF+++E  S+ ++++ +L +GNI F     +  
Sbjct: 320  GFVPIPAAQDD---EMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVF---KKERN 373

Query: 626  TDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSK 685
            TD++ +P+  A Q    ++ I+  +   ++ +  +    + + +A T ++A    +A++K
Sbjct: 374  TDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAK 433

Query: 686  ALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQ 745
            A Y RLF WI+ R+N  L          G   +GILDI GFE F+ NSFEQLCIN  NE+
Sbjct: 434  ATYERLFRWILTRVNKALDKTHR----QGASFLGILDIAGFEIFEVNSFEQLCINYTNEK 489

Query: 746  IQYYFNQHVFALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQ--KPLGLLALLDEESRFP 802
            +Q  FN  +F LEQ EYQ EGI+   +++  D +P +++  +   P G+LALLDEE  FP
Sbjct: 490  LQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP 549

Query: 803  QATDQTLVDKF--EDNLRCKYFWRPKGV--ELCFGIQHYAGKVLYDASGVLEKNRDTLPA 858
            +ATD++ V+K   E     K F +PK +  +  F I HYAGKV Y+AS  L KN D L  
Sbjct: 550  KATDKSFVEKLCTEQGSHPK-FQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLND 608

Query: 859  DVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIR 918
            +V  +L  S +  +  L+   + +   L Q  A++T   SSLP   SA K K        
Sbjct: 609  NVTSLLNASSDKFVADLWK-DVDRIVGLDQ-MAKMT--ESSLP---SASKTKKGMF---- 657

Query: 919  HPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLR 978
                      +TV   ++  L  L++ +    P+FVRCI PN ++ + +     VL QLR
Sbjct: 658  ----------RTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLR 707

Query: 979  STGILETVSIRRQGYSHRILFEEFVKRYYYLAFTA-HQTPLASKESCVAILEKSRLDH-- 1035
              G+LE + I RQG+ +RI+F+EF +RY  LA  A  +  +  K++C+ +++   LD   
Sbjct: 708  CNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNL 767

Query: 1036 WVLGKTKVFLK---YYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREK 1086
            + +G++K+F +     H+E+   L  ++   ++  QA  +G+L  + + K +++
Sbjct: 768  YRIGQSKIFFRTGVLAHLEEERDL--KITDVIMAFQAMCRGYLARKAFAKRQQQ 819


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score =  403 bits (1036), Expect = e-112
 Identities = 224/553 (40%), Positives = 327/553 (59%), Gaps = 14/553 (2%)

Query: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405
           DDL NL  L E  ++  L+ R+    IYTY G IL+A+NPF+ L IY+P++ ++Y   + 
Sbjct: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208

Query: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464
               PH+FA AD AY  M+    +QCIVISGESGSGKT+S + ++  LT L  K     +
Sbjct: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268

Query: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524
              IL    ++EAFGN+ TA N+NSSRFGK++++ +  +G+V GA + +YLLEKSR++ Q
Sbjct: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328

Query: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEA 584
              E+N+H+FYY+  G+  +++  +F+L + +   Y+     +    I   E  +  FE 
Sbjct: 329 EKDERNYHVFYYLLLGVSEEER-QEFQLKQPEDYFYLNQHNLK----IEDGEDLKHDFER 383

Query: 585 IQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVL 644
           ++    ++GF       ++ +L+ IL +GN+ +   ++  + +  EV   E L   + +L
Sbjct: 384 LKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGRE-EGLEVGPPEVLDTLSQLL 442

Query: 645 CISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQ 704
            +  E L E LT    VT  + +I   ++  A   RD+M+K+LY  LF WIV RIN  L 
Sbjct: 443 KVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALL 502

Query: 705 PDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQN 764
             +++  A   +++G+LDIFGFE+F+RNSFEQ CIN ANEQ+QYYFNQH+F LEQ EYQ 
Sbjct: 503 NKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQG 562

Query: 765 EGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKF----EDNLRCK 820
           EGI    + Y DN   + +  +KP GL  LLDEES FP AT QTL+ KF    EDN   K
Sbjct: 563 EGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN---K 619

Query: 821 YFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPL 880
           YF     +E  F IQH+AGKV Y      EKN D +  D+V +LR S++  +++L  +  
Sbjct: 620 YFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDP 679

Query: 881 TKTGNLAQTRARI 893
                 A  RA I
Sbjct: 680 VAVFRWAVLRAAI 692



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 61/173 (35%), Positives = 103/173 (59%), Gaps = 10/173 (5%)

Query: 927  KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986
            K  ++++ F+ SL  LL  +   +P F+RCI+ N +++ L F  E VL QLR TG+LETV
Sbjct: 823  KPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETV 882

Query: 987  SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLD--HWVLGKTKVF 1044
             IRR GYS +  F++F +++  L     Q     +E    +LEK ++D  ++ +GKTKVF
Sbjct: 883  RIRRSGYSAKYTFQDFTEQFQVLLPKDAQ---PCREVISTLLEKMKIDKRNYQIGKTKVF 939

Query: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQS 1096
            LK    + L   L REV+ ++++LQ++ +  L  R + +++    + A+ IQ+
Sbjct: 940  LKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMK----RAAVTIQA 988


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score =  403 bits (1036), Expect = e-112
 Identities = 224/553 (40%), Positives = 327/553 (59%), Gaps = 14/553 (2%)

Query: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405
           DDL NL  L E  ++  L+ R+    IYTY G IL+A+NPF+ L IY+P++ ++Y   + 
Sbjct: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208

Query: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464
               PH+FA AD AY  M+    +QCIVISGESGSGKT+S + ++  LT L  K     +
Sbjct: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268

Query: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524
              IL    ++EAFGN+ TA N+NSSRFGK++++ +  +G+V GA + +YLLEKSR++ Q
Sbjct: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328

Query: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEA 584
              E+N+H+FYY+  G+  +++  +F+L + +   Y+     +    I   E  +  FE 
Sbjct: 329 EKDERNYHVFYYLLLGVSEEER-QEFQLKQPEDYFYLNQHNLK----IEDGEDLKHDFER 383

Query: 585 IQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVL 644
           ++    ++GF       ++ +L+ IL +GN+ +   ++  + +  EV   E L   + +L
Sbjct: 384 LKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGRE-EGLEVGPPEVLDTLSQLL 442

Query: 645 CISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQ 704
            +  E L E LT    VT  + +I   ++  A   RD+M+K+LY  LF WIV RIN  L 
Sbjct: 443 KVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALL 502

Query: 705 PDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQN 764
             +++  A   +++G+LDIFGFE+F+RNSFEQ CIN ANEQ+QYYFNQH+F LEQ EYQ 
Sbjct: 503 NKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQG 562

Query: 765 EGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKF----EDNLRCK 820
           EGI    + Y DN   + +  +KP GL  LLDEES FP AT QTL+ KF    EDN   K
Sbjct: 563 EGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN---K 619

Query: 821 YFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPL 880
           YF     +E  F IQH+AGKV Y      EKN D +  D+V +LR S++  +++L  +  
Sbjct: 620 YFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDP 679

Query: 881 TKTGNLAQTRARI 893
                 A  RA I
Sbjct: 680 VAVFRWAVLRAAI 692



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 61/173 (35%), Positives = 103/173 (59%), Gaps = 10/173 (5%)

Query: 927  KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986
            K  ++++ F+ SL  LL  +   +P F+RCI+ N +++ L F  E VL QLR TG+LETV
Sbjct: 823  KPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETV 882

Query: 987  SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLD--HWVLGKTKVF 1044
             IRR GYS +  F++F +++  L     Q     +E    +LEK ++D  ++ +GKTKVF
Sbjct: 883  RIRRSGYSAKYTFQDFTEQFQVLLPKDAQ---PCREVISTLLEKMKIDKRNYQIGKTKVF 939

Query: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQS 1096
            LK    + L   L REV+ ++++LQ++ +  L  R + +++    + A+ IQ+
Sbjct: 940  LKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMK----RAAVTIQA 988


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score =  402 bits (1033), Expect = e-111
 Identities = 264/815 (32%), Positives = 423/815 (51%), Gaps = 78/815 (9%)

Query: 299  KVLFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDT 358
            K   + ++  KV  + ++   V     + M    P       K+   +D+  L  L E  
Sbjct: 48   KAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPP-------KFDKIEDMAMLTFLHEPA 100

Query: 359  IIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADA 418
            +++ L+ RY   +IYTY G   + +NP++ L +Y+P+    Y G KR+  PPHIF+ +D 
Sbjct: 101  VLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDN 160

Query: 419  AYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQ----------TLREKI 468
            AYQ M+T  ++Q I+I+GESG+GKT +   ++Q+   +    ++          TL ++I
Sbjct: 161  AYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQI 220

Query: 469  LQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAARE 528
            +Q N  +EAFGN+ T  NDNSSRFGK++ + F  TG +  A I  YLLEKSRVI Q   E
Sbjct: 221  IQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAE 280

Query: 529  KNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHC 588
            +++HIFY I +  + + +L D  L    P  Y     G       +      +  A  + 
Sbjct: 281  RDYHIFYQILS--NKKPELLDMLLITNNPYDYAFISQGETT---VASIDDAEELMATDNA 335

Query: 589  FRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISP 648
            F ++GFT +E +S+Y++   I++ GN++F     + + +++E    E    +A ++ ++ 
Sbjct: 336  FDVLGFTSEEKNSMYKLTGAIMHFGNMKFKL---KQREEQAEPDGTEEADKSAYLMGLNS 392

Query: 649  EELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLL---QP 705
             +L + L    V    E + +   V +      A++KA+Y R+F+W+V RIN  L   QP
Sbjct: 393  ADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQP 452

Query: 706  DENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNE 765
             +          +G+LDI GFE F  NSFEQLCIN  NE++Q +FN H+F LEQ EY+ E
Sbjct: 453  RQYF--------IGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKE 504

Query: 766  GIDAVPVEY-EDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNL--RCKYF 822
            GI+   +++  D +  +D+ ++KP+G++++L+EE  FP+ATD T   K  DN   +   F
Sbjct: 505  GIEWTFIDFGMDLQACIDL-IEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANF 563

Query: 823  WRPKGV----ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSI 878
             +P+ +    E  F + HYAG V Y+  G L+KN+D L   VV + + S   LL  LF+ 
Sbjct: 564  QKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFA- 622

Query: 879  PLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYS 938
                             A +  P     GKAK                  QTV++  R +
Sbjct: 623  ---------------NYAGADAPIEKGKGKAK-------------KGSSFQTVSALHREN 654

Query: 939  LMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRIL 998
            L  L++ +    PHFVRCI PN+ +         V+ QLR  G+LE + I R+G+ +RIL
Sbjct: 655  LNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRIL 714

Query: 999  FEEFVKRYYYL--AFTAHQTPLASKESCVAILEKSRLDH--WVLGKTKVFLKYYHVEQLN 1054
            + +F +RY  L  A       + S++    +L    +DH  +  G TKVF K   +  L 
Sbjct: 715  YGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLE 774

Query: 1055 LLLREVIGRVVV-LQAYTKGWLGARRYKKVREKRE 1088
             +  E + R++  +QA ++G L    YKK+ E+R+
Sbjct: 775  EMRDERLSRIITRIQAQSRGVLARMEYKKLLERRD 809


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score =  399 bits (1026), Expect = e-111
 Identities = 268/817 (32%), Positives = 428/817 (52%), Gaps = 80/817 (9%)

Query: 299  KVLFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDT 358
            K   L ++  KV+ + ++   V     + +    P       K+   +D+  L  L E  
Sbjct: 48   KAKILSREGGKVIAETENGKTVTVKEDQVLQQNPP-------KFDKIEDMAMLTFLHEPA 100

Query: 359  IIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADA 418
            ++  L++RYA  +IYTY G   + +NP++ L +Y+ +    Y G KR+  PPHIF+ +D 
Sbjct: 101  VLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDN 160

Query: 419  AYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-----------KANNQTLREK 467
            AYQ M+T  ++Q I+I+GESG+GKT +   ++Q+   +             AN  TL ++
Sbjct: 161  AYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQ 220

Query: 468  ILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAR 527
            I+Q N  +EAFGN+ T  NDNSSRFGK++ + F  TG +  A I  YLLEKSRVI Q   
Sbjct: 221  IIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKA 280

Query: 528  EKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQH 587
            E+N+HIFY I +  + + +L D  L    P  Y     G V   + S +    +  A   
Sbjct: 281  ERNYHIFYQILS--NKKPELLDMLLVTNNPYDYAFVSQGEV--SVASIDD-SEELMATDS 335

Query: 588  CFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCIS 647
             F ++GFT +E   VY++   I++ GN++F     + + +++E    E    +A ++ ++
Sbjct: 336  AFDVLGFTSEEKAGVYKLTGAIMHYGNMKF---KQKQREEQAEPDGTEDADKSAYLMGLN 392

Query: 648  PEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLL---Q 704
              +L + L    V    E + +  +V +      A++KA+Y ++F+W+V RIN  L   Q
Sbjct: 393  SADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLETKQ 452

Query: 705  PDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQN 764
            P +          +G+LDI GFE F  NSFEQLCIN  NE++Q +FN H+F LEQ EY+ 
Sbjct: 453  PRQYF--------IGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 504

Query: 765  EGIDAVPVEY-EDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNL--RCKY 821
            EGI+   +++  D +  +D+ ++KP+G++++L+EE  FP+ATD T   K  DN   +   
Sbjct: 505  EGIEWTFIDFGMDLQACIDL-IEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNN 563

Query: 822  FWRPKGV----ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFS 877
            F +P+ +    E  F + HYAG V Y+  G LEKN+D L   VV + + S   L+  LFS
Sbjct: 564  FQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFS 623

Query: 878  IPLT-KTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFR 936
               T  TG+  +++                GK K  +               QTV++  R
Sbjct: 624  SYATADTGDSGKSK---------------GGKKKGSSF--------------QTVSALHR 654

Query: 937  YSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQGYSHR 996
             +L  L++ +    PHFVRCI PN+ +         V+ QLR  G+LE + I R+G+ +R
Sbjct: 655  ENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNR 714

Query: 997  ILFEEFVKRYYYLAFTA--HQTPLASKESCVAILEKSRLDH--WVLGKTKVFLKYYHVEQ 1052
            IL+ +F +RY  L   A      + S++    +L    +DH  +  G TKVF K   +  
Sbjct: 715  ILYGDFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGL 774

Query: 1053 LNLLLREVIGRVVV-LQAYTKGWLGARRYKKVREKRE 1088
            L  +  E + R++  +QA  +G L    +KK+ E+R+
Sbjct: 775  LEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRD 811


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score =  399 bits (1025), Expect = e-110
 Identities = 266/795 (33%), Positives = 426/795 (53%), Gaps = 74/795 (9%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            K+   +D+  L  L+E +++H L++RY   LIYTY G   + +NP++ L IY+     +Y
Sbjct: 103  KFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKA- 459
             G KR   PPH++A  + AY+ M+   +DQ I+ +GESG+GKTE+   ++Q+L  +  + 
Sbjct: 163  RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222

Query: 460  ---------------NNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTG 504
                           +   L  ++LQ N ++EAFGN+ T  NDNSSRFGK++ + F   G
Sbjct: 223  KGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAG 282

Query: 505  VVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADE 564
             ++GA I  YLLEKSR I+QA  E +FHIFY +  G   Q K +D  L      R++ + 
Sbjct: 283  YIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLK-ADLLLEPCSHYRFLTNG 341

Query: 565  TGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQH 624
                    +S    R  F+      R++GF+ +E+ S+ R+++ +L  GNI   A+  + 
Sbjct: 342  PS------SSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI---ALKRER 392

Query: 625  QTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMS 684
             TD++ +P+  A Q    +L +   +   AL +  +    + + +A T ++A    +A++
Sbjct: 393  NTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALA 452

Query: 685  KALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANE 744
            KA Y RLF W+V R+N  L          G   +GILDI GFE FQ NSFEQLCIN  NE
Sbjct: 453  KATYERLFRWLVLRLNRALDRSPR----QGASFLGILDIAGFEIFQLNSFEQLCINYTNE 508

Query: 745  QIQYYFNQHVFALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQ--KPLGLLALLDEESRF 801
            ++Q  FN  +F LEQ EYQ EGI    +++  D +P +D+  +   P GLLALLDEE  F
Sbjct: 509  KLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWF 568

Query: 802  PQATDQTLVDKF-EDNLRCKYFWRPKGV--ELCFGIQHYAGKVLYDASGVLEKNRDTLPA 858
            P+ATD++ V+K  ++      F RP+ +  +  F + HYAGKV Y A+  L KN D L  
Sbjct: 569  PKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLND 628

Query: 859  DVVVVLRTSENMLLQQLF--------------SIPLTKTGNLAQTRARITVASSSLPPHF 904
            +V  +L  S + L  +++              S P +  G+  +        SS++ P  
Sbjct: 629  NVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAER-------CSSAISPPG 681

Query: 905  SAGKAKVDTLEVIRHPEETTNMKR---QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPND 961
              G   ++ +  +         +R   +TV   ++ SL  L++ +    P FVRCI PN 
Sbjct: 682  VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNH 741

Query: 962  DREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTP---L 1018
            ++ A +     VL QLR  G+LE + I RQG+ +RILF+EF +RY  L  T +  P   +
Sbjct: 742  EKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEIL--TPNAIPKGFM 799

Query: 1019 ASKESCVAILEKSRLDH--WVLGKTKVFLKYYHVEQL----NLLLREVIGRVVVLQAYTK 1072
              K++C  +++   LD   + +G++K+F +   + QL    +L + ++I   V  QA  +
Sbjct: 800  DGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDII---VSFQAAAR 856

Query: 1073 GWLGARRYKKVREKR 1087
            G+L  R ++K ++++
Sbjct: 857  GYLARRAFQKRQQQQ 871


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score =  398 bits (1022), Expect = e-110
 Identities = 265/775 (34%), Positives = 416/775 (53%), Gaps = 67/775 (8%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            ++ L +D+  +  L+E +++H L++RYA  +IYTY G   + +NP++ L +Y+      Y
Sbjct: 124  RFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAY 183

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLT------ 454
             G +R+ +PPHI+A AD AY  M+    +Q ++I+GESG+GKT +   ++Q+        
Sbjct: 184  KGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALG 243

Query: 455  --------FLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVV 506
                    FL      TL ++I++ N  +EAFGN+ T  NDNSSRFGK++ + F P+G +
Sbjct: 244  DGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKL 303

Query: 507  MGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETG 566
              A I  YLLEKSRVI Q   E+++H++Y I +G   + +L D  L    P  Y     G
Sbjct: 304  ASADIDSYLLEKSRVIFQLPGERSYHVYYQILSG--RKPELQDMLLLSMNPYDYHFCSQG 361

Query: 567  RVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQT 626
             +  D  +      +  A  H   I+GF+  E  + Y+I+  +L+ GN++F     + + 
Sbjct: 362  VITVDNMNDGE---ELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKF---KQKQRE 415

Query: 627  DKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKA 686
            +++E    E+   AA ++ +S  +L + L    V    E + +  +V++      A++KA
Sbjct: 416  EQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKA 475

Query: 687  LYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQI 746
             Y RLF W+V+RIN  L              +G+LDI GFE F+ NSFEQLCIN  NE++
Sbjct: 476  TYDRLFRWLVSRINQTLDT-----KLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKL 530

Query: 747  QYYFNQHVFALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQKPLGLLALLDEESRFPQAT 805
            Q +FNQH+F LEQ EY+ EGID V +++  D +P +D+ ++KPLG+L++L+EE  FP+A+
Sbjct: 531  QQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDL-IEKPLGILSILEEECMFPKAS 589

Query: 806  DQTLVDKFEDNLRCKY--FWRPKG-----VELCFGIQHYAGKVLYDASGVLEKNRDTLPA 858
            D +   K  DN   K   F +P+       +  F + HYAG V Y   G LEKN+D L  
Sbjct: 590  DASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNE 649

Query: 859  DVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIR 918
             VV + + S+N LL  L+        N A         S S  P  S  K K        
Sbjct: 650  TVVPIFQKSQNRLLATLYE-------NYA--------GSCSTEPPKSGVKEK-------- 686

Query: 919  HPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLR 978
                      QTV+   + +L  L++ +   QPHFVRCI PN+++         VL QLR
Sbjct: 687  ---RKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLR 743

Query: 979  STGILETVSIRRQGYSHRILFEEFVKRYYYLAFTA--HQTPLASKESCVAILEKSRLDH- 1035
              G+LE + I RQG+ +R+L+ +F +RY  L  +A    T + S+++   +L    LDH 
Sbjct: 744  CNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHT 803

Query: 1036 -WVLGKTKVFLKYYHVEQLNLLLREVIGRVV-VLQAYTKGWLGARRYKKVREKRE 1088
             +  G TKVF K   +  L  L  + + +V+ +LQA ++G L    Y+++   R+
Sbjct: 804  QYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRD 858


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score =  397 bits (1021), Expect = e-110
 Identities = 260/774 (33%), Positives = 413/774 (53%), Gaps = 68/774 (8%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            KY   +D+  +  L E  +++ L++RYA  +IYTY G   + +NP++ L +Y P+    Y
Sbjct: 84   KYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAY 143

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKAN 460
             G KR   PPHIF+ +D AYQ M+T  ++Q I+I+GESG+GKT +   ++Q+   +    
Sbjct: 144  RGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTG 203

Query: 461  NQ------------TLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMG 508
             +            TL ++I+  N L+EAFGN+ T  NDNSSRFGK++ + F  TG +  
Sbjct: 204  EKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLAS 263

Query: 509  ARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRV 568
            A I  YLLEKSRV+ Q   E+++HIFY I +  + + +L +  L    P  Y     G +
Sbjct: 264  ADIETYLLEKSRVVFQLKAERSYHIFYQITS--NKKPELIEMLLITTNPYDYPFVSQGEI 321

Query: 569  MHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDK 628
               + S +  + +  A      I+GFT++E  S+Y++   +++ GN++F     + + ++
Sbjct: 322  --SVASIDD-QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKF---KQKQREEQ 375

Query: 629  SEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALY 688
            +E    E    AA +  ++  +L +AL    V    E + +  TV++ ++   A++KA+Y
Sbjct: 376  AEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVY 435

Query: 689  GRLFSWIVNRINTLL---QPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQ 745
             ++F W+V RIN  L   QP +          +G+LDI GFE F  NS EQLCIN  NE+
Sbjct: 436  EKMFLWMVARINQQLDTKQPRQYF--------IGVLDIAGFEIFDFNSLEQLCINFTNEK 487

Query: 746  IQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQAT 805
            +Q +FN H+F LEQ EY+ EGI+   +++  +       ++KP+G+ ++L+EE  FP+AT
Sbjct: 488  LQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKAT 547

Query: 806  DQTLVDKFEDNL--RCKYFWRPKGV----ELCFGIQHYAGKVLYDASGVLEKNRDTLPAD 859
            D +  +K  D    +   F +PK V    E  F + HYAG V Y+ +G LEKN+D L   
Sbjct: 548  DTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNET 607

Query: 860  VVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRH 919
            VV + + S    L QLFS   T  G  A   A+              GK K  +      
Sbjct: 608  VVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAK------------KGGKKKGSSF----- 650

Query: 920  PEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRS 979
                     QTV++ FR +L  L++ +    PHFVRCI PN+ +       E VL QLR 
Sbjct: 651  ---------QTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRC 701

Query: 980  TGILETVSIRRQGYSHRILFEEFVKRYYYLAFTA--HQTPLASKESCVAILEKSRLDH-- 1035
             G+LE + I R+G+  RIL+ +F +RY  L  +A      + SK++   +L    +DH  
Sbjct: 702  NGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQ 761

Query: 1036 WVLGKTKVFLKYYHVEQLNLLLREVIGRVVV-LQAYTKGWLGARRYKKVREKRE 1088
            +  G TKVF K   +  L  +  + + +++   QA  +G+L    Y+++ E+RE
Sbjct: 762  YKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERRE 815


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score =  397 bits (1021), Expect = e-110
 Identities = 260/774 (33%), Positives = 413/774 (53%), Gaps = 68/774 (8%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            KY   +D+  +  L E  +++ L++RYA  +IYTY G   + +NP++ L +Y P+    Y
Sbjct: 84   KYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAY 143

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKAN 460
             G KR   PPHIF+ +D AYQ M+T  ++Q I+I+GESG+GKT +   ++Q+   +    
Sbjct: 144  RGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTG 203

Query: 461  NQ------------TLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMG 508
             +            TL ++I+  N L+EAFGN+ T  NDNSSRFGK++ + F  TG +  
Sbjct: 204  EKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLAS 263

Query: 509  ARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRV 568
            A I  YLLEKSRV+ Q   E+++HIFY I +  + + +L +  L    P  Y     G +
Sbjct: 264  ADIETYLLEKSRVVFQLKAERSYHIFYQITS--NKKPELIEMLLITTNPYDYPFVSQGEI 321

Query: 569  MHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDK 628
               + S +  + +  A      I+GFT++E  S+Y++   +++ GN++F     + + ++
Sbjct: 322  --SVASIDD-QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKF---KQKQREEQ 375

Query: 629  SEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALY 688
            +E    E    AA +  ++  +L +AL    V    E + +  TV++ ++   A++KA+Y
Sbjct: 376  AEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVY 435

Query: 689  GRLFSWIVNRINTLL---QPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQ 745
             ++F W+V RIN  L   QP +          +G+LDI GFE F  NS EQLCIN  NE+
Sbjct: 436  EKMFLWMVARINQQLDTKQPRQYF--------IGVLDIAGFEIFDFNSLEQLCINFTNEK 487

Query: 746  IQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQAT 805
            +Q +FN H+F LEQ EY+ EGI+   +++  +       ++KP+G+ ++L+EE  FP+AT
Sbjct: 488  LQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKAT 547

Query: 806  DQTLVDKFEDNL--RCKYFWRPKGV----ELCFGIQHYAGKVLYDASGVLEKNRDTLPAD 859
            D +  +K  D    +   F +PK V    E  F + HYAG V Y+ +G LEKN+D L   
Sbjct: 548  DTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNET 607

Query: 860  VVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRH 919
            VV + + S    L QLFS   T  G  A   A+              GK K  +      
Sbjct: 608  VVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAK------------KGGKKKGSSF----- 650

Query: 920  PEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRS 979
                     QTV++ FR +L  L++ +    PHFVRCI PN+ +       E VL QLR 
Sbjct: 651  ---------QTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRC 701

Query: 980  TGILETVSIRRQGYSHRILFEEFVKRYYYLAFTA--HQTPLASKESCVAILEKSRLDH-- 1035
             G+LE + I R+G+  RIL+ +F +RY  L  +A      + SK++   +L    +DH  
Sbjct: 702  NGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQ 761

Query: 1036 WVLGKTKVFLKYYHVEQLNLLLREVIGRVVV-LQAYTKGWLGARRYKKVREKRE 1088
            +  G TKVF K   +  L  +  + + +++   QA  +G+L    Y+++ E+RE
Sbjct: 762  YKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERRE 815


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score =  397 bits (1020), Expect = e-110
 Identities = 264/770 (34%), Positives = 416/770 (54%), Gaps = 65/770 (8%)

Query: 341  KYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLY 400
            K+   +D+  L  L+E +++H L++RY   LIYTY G   + +NP++ L IY+     +Y
Sbjct: 103  KFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162

Query: 401  HGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKAN 460
             G KR   PPH++A  + AY+ M+   +DQ I+ +GESG+GKTE+   ++Q+L  +  + 
Sbjct: 163  RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222

Query: 461  N--------QTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARIS 512
                       L  ++LQ N ++EAFGN+ T  NDNSSRFGK++ + F   G ++GA I 
Sbjct: 223  KGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIE 282

Query: 513  EYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDI 572
             YLLEKSR I+QA  E +FHIFY +  G   Q K +D  L      R++ +         
Sbjct: 283  TYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLK-ADLLLEPCSHYRFLTNGPS------ 335

Query: 573  TSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVP 632
            +S    R  F+      R++GF+ +E+ S+ R+++ +L  GNI   A+  +  TD++ +P
Sbjct: 336  SSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI---ALKRERNTDQATMP 392

Query: 633  NAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLF 692
            +  A Q    +L +   +   AL +  +    + + +A T ++A    +A++KA Y RLF
Sbjct: 393  DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLF 452

Query: 693  SWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQ 752
             W+V R+N  L          G   +GILDI GFE FQ NSFEQLCIN  NE++Q  FN 
Sbjct: 453  RWLVLRLNRALDRSPR----QGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNH 508

Query: 753  HVFALEQMEYQNEGIDAVPVEYE-DNRPLLDMFLQ--KPLGLLALLDEESRFPQATDQTL 809
             +F LEQ EYQ EGI    +++  D +P +D+  +   P GLLALLDEE  FP+ATD++ 
Sbjct: 509  TMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSF 568

Query: 810  VDKF-EDNLRCKYFWRPKGV--ELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRT 866
            V+K  ++      F RP+ +  +  F + HYAGKV Y A+  L KN D L  +V  +L  
Sbjct: 569  VEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQ 628

Query: 867  SENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNM 926
            S + L  +++   +     L Q         SSL      G+ +                
Sbjct: 629  STDRLTAEIWK-DVEGIVGLEQV--------SSLGDGPPGGRPRRGMF------------ 667

Query: 927  KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986
              +TV   ++ SL  L++ +    P FVRCI PN ++ A +     VL QLR  G+LE +
Sbjct: 668  --RTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGI 725

Query: 987  SIRRQGYSHRILFEEFVKRYYYLAFTAHQTP---LASKESCVAILEKSRLDH--WVLGKT 1041
             I RQG+ +RILF+EF +RY  L  T +  P   +  K++C  +++   LD   + +G++
Sbjct: 726  RICRQGFPNRILFQEFRQRYEIL--TPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQS 783

Query: 1042 KVFLKYYHVEQL----NLLLREVIGRVVVLQAYTKGWLGARRYKKVREKR 1087
            K+F +   + QL    +L + ++I   V  QA  +G+L  R ++K ++++
Sbjct: 784  KIFFRAGVLAQLEEERDLKVTDII---VSFQAAARGYLARRAFQKRQQQQ 830


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,970,307
Number of Sequences: 37866
Number of extensions: 2367929
Number of successful extensions: 8547
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 659
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 5688
Number of HSP's gapped (non-prelim): 1310
length of query: 1314
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1200
effective length of database: 13,930,794
effective search space: 16716952800
effective search space used: 16716952800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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