BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55953085 G protein-coupled receptor 120 [Homo sapiens] (377 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55953085 G protein-coupled receptor 120 [Homo sapiens] 746 0.0 gi|222080109 orexin receptor 2 [Homo sapiens] 102 7e-22 gi|167000885 galanin receptor 1 [Homo sapiens] 96 4e-20 gi|4557861 somatostatin receptor 3 [Homo sapiens] 94 2e-19 gi|4557865 somatostatin receptor 5 [Homo sapiens] 87 2e-17 gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 87 3e-17 gi|53828924 G protein-coupled receptor 7 [Homo sapiens] 87 3e-17 gi|5174595 melatonin receptor 1B [Homo sapiens] 86 5e-17 gi|221139879 G protein-coupled receptor 63 [Homo sapiens] 85 1e-16 gi|13540557 G protein-coupled receptor 63 [Homo sapiens] 85 1e-16 gi|149944554 somatostatin receptor 4 [Homo sapiens] 84 2e-16 gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo sa... 84 3e-16 gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo s... 84 3e-16 gi|4557859 somatostatin receptor 2 [Homo sapiens] 84 3e-16 gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 84 3e-16 gi|30581170 CC chemokine receptor 3 [Homo sapiens] 82 1e-15 gi|4502637 CC chemokine receptor 3 [Homo sapiens] 82 1e-15 gi|222080095 orexin receptor 1 [Homo sapiens] 81 1e-15 gi|4503905 galanin receptor 2 [Homo sapiens] 81 1e-15 gi|4502607 cholecystokinin A receptor [Homo sapiens] 80 3e-15 gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 80 3e-15 gi|170932505 neuromedin U receptor 2 [Homo sapiens] 80 4e-15 gi|28875799 cholecystokinin B receptor [Homo sapiens] 79 9e-15 gi|63477962 opioid receptor, delta 1 [Homo sapiens] 78 1e-14 gi|88758590 G protein-coupled receptor 24 [Homo sapiens] 77 2e-14 gi|5174593 melatonin receptor 1A [Homo sapiens] 77 3e-14 gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 75 1e-13 gi|66932941 XC chemokine receptor 1 [Homo sapiens] 75 1e-13 gi|4885339 XC chemokine receptor 1 [Homo sapiens] 75 1e-13 gi|4885057 apelin receptor [Homo sapiens] 74 2e-13 >gi|55953085 G protein-coupled receptor 120 [Homo sapiens] Length = 377 Score = 746 bits (1925), Expect = 0.0 Identities = 377/377 (100%), Positives = 377/377 (100%) Query: 1 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC 60 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC Sbjct: 1 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC 60 Query: 61 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL 120 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL Sbjct: 61 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL 120 Query: 121 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV 180 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV Sbjct: 121 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV 180 Query: 181 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDA 240 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDA Sbjct: 181 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDA 240 Query: 241 RAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI 300 RAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI Sbjct: 241 RAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI 300 Query: 301 LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA 360 LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA Sbjct: 301 LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA 360 Query: 361 ILTDTSVKRNDLSIISG 377 ILTDTSVKRNDLSIISG Sbjct: 361 ILTDTSVKRNDLSIISG 377 >gi|222080109 orexin receptor 2 [Homo sapiens] Length = 444 Score = 102 bits (253), Expect = 7e-22 Identities = 90/333 (27%), Positives = 158/333 (47%), Gaps = 41/333 (12%) Query: 48 VLIFAVSLLGNVCALVLVARRRR-RGATACLVLNLFCADLLF-ISAIPLVLAVRWTEAWL 105 +++F V+L+GNV V V + R T ++NL AD+L I+ +P L V TE W Sbjct: 62 IIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWF 121 Query: 106 LGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGY 165 G C ++ Y+ T+S SV++LTL+ ++L+R I H + +RAR ++ +IW Sbjct: 122 FGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICH-PLMFKSTAKRARNSIV-IIWIV 179 Query: 166 SAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEI---SWDVSFVTLNFLVPGLV 222 S + +P + PG + ++ T+ GEI + + F + ++ P + Sbjct: 180 SCIIMIPQAIVME-CSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCL 238 Query: 223 IVISYSKILQTSEHLLDARAVVTHSEITKASRKRL---------------TVSLAYSESH 267 +V++Y +I + L R + S + + K L +S +E Sbjct: 239 MVLAYLQIFRK----LWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIK 294 Query: 268 QIRVSQQDFRLFRTLFLLMVSFFIMWSPI-IITILLILIQNF-----KQDLVIWPSLFFW 321 QIR ++ R+ L ++++ F I + PI I+ +L + F ++ + W + W Sbjct: 295 QIRARRKTARM---LMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHW 351 Query: 322 VVAFTFANSALNPILYNMT--LCRNEWKKIFCC 352 +V +ANSA NPI+YN R E+K F C Sbjct: 352 LV---YANSAANPIIYNFLSGKFREEFKAAFSC 381 >gi|167000885 galanin receptor 1 [Homo sapiens] Length = 349 Score = 96.3 bits (238), Expect = 4e-20 Identities = 93/338 (27%), Positives = 150/338 (44%), Gaps = 45/338 (13%) Query: 42 VETTVLVLIFAVSLLGNVCALVLVARRRR---RGATACLVLNLFCADLLFIS-AIPLVLA 97 V V LIFA+ +LGN + ++AR + R T +LNL ADL ++ IP Sbjct: 35 VTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQAT 94 Query: 98 VRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAV 157 V W+LG C + Y T+S V+I TLAA+S++R V IVH +R R + Sbjct: 95 VYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALL 154 Query: 158 LLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFL 217 + IW S A P+ + R + C WP + ++ V +L Sbjct: 155 GVGCIWALSIAMASPVAYHQGLFHPRASNQ----TFCWEQWPDPRHKKAYVVCTFVFGYL 210 Query: 218 VPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFR 277 +P L+I Y+K+L HL H ++ S+K SE+ + + +Q Sbjct: 211 LPLLLICFCYAKVL---NHL--------HKKLKNMSKK--------SEASKKKTAQ---- 247 Query: 278 LFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVV---AFTFANSALNP 334 T+ +++V F I W P I L F + P+ F + + ++NS++NP Sbjct: 248 ---TVLVVVVVFGISWLPHHIIHLWAEFGVFP----LTPASFLFRITAHCLAYSNSSVNP 300 Query: 335 ILYNMTL--CRNEWKKIFCCFWFPEKGAILTDTSVKRN 370 I+Y R +K++F C K + L+DT ++ Sbjct: 301 IIYAFLSENFRKAYKQVFKC--HIRKDSHLSDTKESKS 336 >gi|4557861 somatostatin receptor 3 [Homo sapiens] Length = 418 Score = 94.0 bits (232), Expect = 2e-19 Identities = 78/297 (26%), Positives = 129/297 (43%), Gaps = 38/297 (12%) Query: 46 VLVLIFAVSLLGNVCALVLVARRRRR-GATACLVLNLFCADLLFISAIPLVLAVRWTEAW 104 V +++ V LLGN + +V R T +LNL AD LF+ +P + A W Sbjct: 50 VYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYW 109 Query: 105 LLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWG 164 G + C L+ V ++ +I L +S++R + +VH R R + A +W Sbjct: 110 PFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWV 169 Query: 165 YSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFV----TLNFLVPG 220 SAV LP+ VF G + +S C + WP +W F+ L F P Sbjct: 170 ASAVVVLPVVVF--------SGVPRGMSTCHMQWP--EPAAAWRAGFIIYTAALGFFGPL 219 Query: 221 LVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFR 280 LVI + Y I+ ++ A R+ ++ S Q R + + R+ R Sbjct: 220 LVICLCYLLIV---------------VKVRSAGRR------VWAPSCQ-RRRRSERRVTR 257 Query: 281 TLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILY 337 + ++ F + W P + ++ ++ ++ + L+F VVA +ANS NPILY Sbjct: 258 MVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFF-GLYFLVVALPYANSCANPILY 313 >gi|4557865 somatostatin receptor 5 [Homo sapiens] Length = 364 Score = 87.0 bits (214), Expect = 2e-17 Identities = 84/323 (26%), Positives = 132/323 (40%), Gaps = 53/323 (16%) Query: 40 AAVETTVLVLIFAVSLLGNVCALVLVAR-RRRRGATACLVLNLFCADLLFISAIPLVLAV 98 A + + +L+ A L GN + +V R + + T +LNL AD+L++ +P + Sbjct: 40 AVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQ 99 Query: 99 RWTEAWLLGPVACHLLFYVMTLSG---SVTILTLAAVSLERMVCIVHLQRGVRGPGRRAR 155 W GPV C L VMTL G ++ L +S++R + +VH R R Sbjct: 100 NAASFWPFGPVLCRL---VMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVA 156 Query: 156 AVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFV--- 212 + A W S +LPL VF V QE C WP G W F+ Sbjct: 157 KLASAAAWVLSLCMSLPLLVFADV---------QEGGTCNASWPEPVG--LWGAVFIIYT 205 Query: 213 -TLNFLVPGLVIVISYSKILQTSEHLLDARAV-VTHSEITKASRKRLTVSLAYSESHQIR 270 L F P LVI + Y I ++ RA V + + S +++T Sbjct: 206 AVLGFFAPLLVICLCYLLI------VVKVRAAGVRVGCVRRRSERKVT------------ 247 Query: 271 VSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANS 330 R + ++++ F W P ++ L Q+ L+F+VV ++ANS Sbjct: 248 ---------RMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPAS-AGLYFFVVILSYANS 297 Query: 331 ALNPILYNMTL--CRNEWKKIFC 351 NP+LY R ++K+ C Sbjct: 298 CANPVLYGFLSDNFRQSFQKVLC 320 >gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] Length = 381 Score = 86.7 bits (213), Expect = 3e-17 Identities = 77/300 (25%), Positives = 134/300 (44%), Gaps = 46/300 (15%) Query: 50 IFAVSLLGNVCAL-VLVARRRRRGATACLVLNLFCADLLFIS-AIPLVLAVRWTEAWLLG 107 I + ++GN + V++ + R T + NL ADLL + +P L W +G Sbjct: 60 IILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMG 119 Query: 108 PVACHLLFYVMTLSGSVTILTLAAVSLERMVCIV-HLQRGVRGPGRRARAVLLALIWGYS 166 PV CHL+ Y L+ V+ +TL ++L+R CIV HL+ + +R +++ L WG S Sbjct: 120 PVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKI---SKRISFLIIGLAWGIS 176 Query: 167 AVAALPLCVF-----FRVVPQRLPGADQEISICTLIWP----TIPGEISWDVSFVTLNFL 217 A+ A PL +F ++P D EI CT WP +I G + + +S + + ++ Sbjct: 177 ALLASPLAIFREYSLIEIIP------DFEIVACTEKWPGEEKSIYGTV-YSLSSLLILYV 229 Query: 218 VPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFR 277 +P +I SY++I ++ + A H Y + Q + Sbjct: 230 LPLGIISFSYTRIWSKLKNHVSPGAANDH----------------YHQRRQ--------K 265 Query: 278 LFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILY 337 + L ++V F + W P+ L + I + DL + +F ++ NP+LY Sbjct: 266 TTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLY 325 >gi|53828924 G protein-coupled receptor 7 [Homo sapiens] Length = 328 Score = 86.7 bits (213), Expect = 3e-17 Identities = 84/307 (27%), Positives = 139/307 (45%), Gaps = 43/307 (14%) Query: 39 LAAVETTVLVLIFAVSLLGNVCAL-VLVARRRRRGATACLVLNLFCADLLFISAIPLVLA 97 LA V +I AV L GN L VL+ R + T +LNL AD LF +P+ +A Sbjct: 36 LAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIA 95 Query: 98 VRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGR---RA 154 W G + C L+ + + ++ L +S +R + ++ R GR A Sbjct: 96 DFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAA 155 Query: 155 RAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVS---F 211 RAV LA +WG + LP VF R+ ++ G Q C L++P P W S Sbjct: 156 RAVSLA-VWGIVTLVVLPFAVFARLDDEQ--GRRQ----CVLVFPQ-PEAFWWRASRLYT 207 Query: 212 VTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRV 271 + L F +P I + Y+ +L L A + +H++ + ++KR+T Sbjct: 208 LVLGFAIPVSTICVLYTTLLCR----LHAMRLDSHAKALERAKKRVT------------- 250 Query: 272 SQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQ-DLVIWPSLFFWVVAFTFANS 330 F + +L V + W+P ++ ++ L + Q LVI ++ +++ + ++ANS Sbjct: 251 -------FLVVAILAVC-LLCWTPYHLSTVVALTTDLPQTPLVI--AISYFITSLSYANS 300 Query: 331 ALNPILY 337 LNP LY Sbjct: 301 CLNPFLY 307 >gi|5174595 melatonin receptor 1B [Homo sapiens] Length = 362 Score = 85.9 bits (211), Expect = 5e-17 Identities = 87/322 (27%), Positives = 139/322 (43%), Gaps = 35/322 (10%) Query: 39 LAAVETTVLVLIFAVSLLGNVCALVLVARRRR-RGATACLVLNLFCADLLF-ISAIPLVL 96 +A + VL++ AV ++GN+ ++ V R R+ R A +++L ADL+ PL+L Sbjct: 39 VAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLIL 98 Query: 97 AVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARA 156 + + W LG C +VM LS ++ + A+++ R I H R R Sbjct: 99 VAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTP 158 Query: 157 VLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNF 216 + + LIW + VA LP FF + D I CT I + + V ++F Sbjct: 159 LHICLIWLLTVVALLPN--FFVGSLEY----DPRIYSCTFIQTA---STQYTAAVVVIHF 209 Query: 217 LVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDF 276 L+P V+ Y +I + +A RK A ES ++ + D Sbjct: 210 LLPIAVVSFCYLRIWVL---------------VLQARRK------AKPES-RLCLKPSDL 247 Query: 277 RLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPIL 336 R F T+F++ V F I W+P+ L + I + I LF + NS LN I+ Sbjct: 248 RSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIV 307 Query: 337 YNM--TLCRNEWKKIFCCFWFP 356 Y + R E+K+I W P Sbjct: 308 YGLLNQNFRREYKRILLALWNP 329 >gi|221139879 G protein-coupled receptor 63 [Homo sapiens] Length = 419 Score = 84.7 bits (208), Expect = 1e-16 Identities = 81/312 (25%), Positives = 138/312 (44%), Gaps = 29/312 (9%) Query: 37 LVLAAVETTVLVLIFAVSLLGN-VCALVLVARRRRRGATACLVLNLFCADLLF-ISAIPL 94 L L + +++ I VS LGN V L++ + R A L+ +L AD+L + +P Sbjct: 78 LPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPF 137 Query: 95 VLAVRWTEAWLLGPVACH---LLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPG 151 L T W+ G C + F++ + G + L +S++R + IV QR + Sbjct: 138 ALVTILTTRWIFGKFFCRVSAMFFWLFVIEG---VAILLIISIDRFLIIV--QRQDKLNP 192 Query: 152 RRARAVLLALIWGYSAVAALPLCVFFR--VVPQRLPGADQEISICTLIWPTIPGEISWDV 209 RA+ VL+A+ W S A PL V +P R P C + T PG ++ + Sbjct: 193 YRAK-VLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQ-------CVFGYTTNPGYQAYVI 244 Query: 210 SFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQI 269 ++F +P LVI+ S+ IL T H +A + ++ E S+ ++ Q+ Sbjct: 245 LISLISFFIPFLVILYSFMGILNTLRH--NALRIHSYPEGICLSQASKLGLMSLQRPFQM 302 Query: 270 RVSQQ-DFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLF---FWVVAF 325 + R F T+ +L F + W+P L+ F + + F W++ Sbjct: 303 SIDMGFKTRAFTTILILFAVFIVCWAPF---TTYSLVATFSKHFYYQHNFFEISTWLLWL 359 Query: 326 TFANSALNPILY 337 + SALNP++Y Sbjct: 360 CYLKSALNPLIY 371 >gi|13540557 G protein-coupled receptor 63 [Homo sapiens] Length = 419 Score = 84.7 bits (208), Expect = 1e-16 Identities = 81/312 (25%), Positives = 138/312 (44%), Gaps = 29/312 (9%) Query: 37 LVLAAVETTVLVLIFAVSLLGN-VCALVLVARRRRRGATACLVLNLFCADLLF-ISAIPL 94 L L + +++ I VS LGN V L++ + R A L+ +L AD+L + +P Sbjct: 78 LPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPF 137 Query: 95 VLAVRWTEAWLLGPVACH---LLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPG 151 L T W+ G C + F++ + G + L +S++R + IV QR + Sbjct: 138 ALVTILTTRWIFGKFFCRVSAMFFWLFVIEG---VAILLIISIDRFLIIV--QRQDKLNP 192 Query: 152 RRARAVLLALIWGYSAVAALPLCVFFR--VVPQRLPGADQEISICTLIWPTIPGEISWDV 209 RA+ VL+A+ W S A PL V +P R P C + T PG ++ + Sbjct: 193 YRAK-VLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQ-------CVFGYTTNPGYQAYVI 244 Query: 210 SFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQI 269 ++F +P LVI+ S+ IL T H +A + ++ E S+ ++ Q+ Sbjct: 245 LISLISFFIPFLVILYSFMGILNTLRH--NALRIHSYPEGICLSQASKLGLMSLQRPFQM 302 Query: 270 RVSQQ-DFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLF---FWVVAF 325 + R F T+ +L F + W+P L+ F + + F W++ Sbjct: 303 SIDMGFKTRAFTTILILFAVFIVCWAPF---TTYSLVATFSKHFYYQHNFFEISTWLLWL 359 Query: 326 TFANSALNPILY 337 + SALNP++Y Sbjct: 360 CYLKSALNPLIY 371 >gi|149944554 somatostatin receptor 4 [Homo sapiens] Length = 388 Score = 84.3 bits (207), Expect = 2e-16 Identities = 80/310 (25%), Positives = 127/310 (40%), Gaps = 43/310 (13%) Query: 33 GDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVAR-RRRRGATACLVLNLFCADLLFISA 91 GD R + L+ V L+GN + ++ R + + AT +LNL AD LF+ + Sbjct: 40 GDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLS 99 Query: 92 IPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPG 151 +P V + W G V C + V L+ ++ L +S++R V +VH R Sbjct: 100 VPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRR 159 Query: 152 RRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSF 211 ++ +W S + LP+ +F P R Q ++ C L WP +W F Sbjct: 160 PSVAKLINLGVWLASLLVTLPIAIFADTRPAR---GGQAVA-CNLQWP----HPAWSAVF 211 Query: 212 VT----LNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESH 267 V L FL+P L I + Y I+ + A A+ + + S K++T Sbjct: 212 VVYTFLLGFLLPVLAIGLCYLLIVGK----MRAVALRAGWQQRRRSEKKIT--------- 258 Query: 268 QIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTF 327 R + +++V F + W P + LL L V SL ++ Sbjct: 259 ------------RLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLI-----LSY 301 Query: 328 ANSALNPILY 337 ANS NPILY Sbjct: 302 ANSCANPILY 311 >gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo sapiens] Length = 352 Score = 83.6 bits (205), Expect = 3e-16 Identities = 76/300 (25%), Positives = 129/300 (43%), Gaps = 47/300 (15%) Query: 45 TVLVLIFAVSLLGN-VCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEA 103 T+ +IF ++GN + LV+ +++ R T L+L ADLLF+ +P AV Sbjct: 43 TIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPF-WAVDAVAN 101 Query: 104 WLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIW 163 W G C + + T++ ++L LA +SL+R + IVH R A V+ +W Sbjct: 102 WYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVW 161 Query: 164 GYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVI 223 + + +P +F V AD IC +P + + + + ++PG+VI Sbjct: 162 IPALLLTIPDFIFANV-----SEADDRY-ICDRFYPNDLWVVVFQFQHIMVGLILPGIVI 215 Query: 224 VISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLF 283 + Y I+ L++S+ HQ R + +T Sbjct: 216 LSCYCIIIS---------------------------KLSHSKGHQKR------KALKTTV 242 Query: 284 LLMVSFFIMWSPIIITILL---ILIQNFKQDLVIWPSLFFWV---VAFTFANSALNPILY 337 +L+++FF W P I I + IL++ KQ ++ W+ A F + LNPILY Sbjct: 243 ILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILY 302 >gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo sapiens] Length = 356 Score = 83.6 bits (205), Expect = 3e-16 Identities = 76/300 (25%), Positives = 129/300 (43%), Gaps = 47/300 (15%) Query: 45 TVLVLIFAVSLLGN-VCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEA 103 T+ +IF ++GN + LV+ +++ R T L+L ADLLF+ +P AV Sbjct: 47 TIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPF-WAVDAVAN 105 Query: 104 WLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIW 163 W G C + + T++ ++L LA +SL+R + IVH R A V+ +W Sbjct: 106 WYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVW 165 Query: 164 GYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVI 223 + + +P +F V AD IC +P + + + + ++PG+VI Sbjct: 166 IPALLLTIPDFIFANV-----SEADDRY-ICDRFYPNDLWVVVFQFQHIMVGLILPGIVI 219 Query: 224 VISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLF 283 + Y I+ L++S+ HQ R + +T Sbjct: 220 LSCYCIIIS---------------------------KLSHSKGHQKR------KALKTTV 246 Query: 284 LLMVSFFIMWSPIIITILL---ILIQNFKQDLVIWPSLFFWV---VAFTFANSALNPILY 337 +L+++FF W P I I + IL++ KQ ++ W+ A F + LNPILY Sbjct: 247 ILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILY 306 >gi|4557859 somatostatin receptor 2 [Homo sapiens] Length = 369 Score = 83.6 bits (205), Expect = 3e-16 Identities = 77/318 (24%), Positives = 131/318 (41%), Gaps = 46/318 (14%) Query: 41 AVETTVLVLIFAVSLLGNVCALVLVAR-RRRRGATACLVLNLFCADLLFISAIPLVLAVR 99 AV T + ++ + L GN + ++ R + + T +LNL AD LF+ +P + Sbjct: 44 AVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQV 103 Query: 100 WTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLL 159 W G C ++ V ++ +I L +S++R + +VH + + R ++ Sbjct: 104 ALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMIT 163 Query: 160 ALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFV----TLN 215 +WG S + LP+ ++ L S CT+ WP G +W F+ L Sbjct: 164 MAVWGVSLLVILPIMIY-----AGLRSNQWGRSSCTINWPGESG--AWYTGFIIYTFILG 216 Query: 216 FLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQD 275 FLVP +I + Y I+ V S I S KR + + Sbjct: 217 FLVPLTIICLCYLFII----------IKVKSSGIRVGSSKR---------------KKSE 251 Query: 276 FRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSL---FFWVVAFTFANSAL 332 ++ R + +++ F W P I + + + P+L F +VV T+ANS Sbjct: 252 KKVTRMVSIVVAVFIFCWLPFYI----FNVSSVSMAISPTPALKGMFDFVVVLTYANSCA 307 Query: 333 NPILYNMTLCRNEWKKIF 350 NPILY + +KK F Sbjct: 308 NPILY--AFLSDNFKKSF 323 >gi|4758474 G protein-coupled receptor 10 [Homo sapiens] Length = 370 Score = 83.6 bits (205), Expect = 3e-16 Identities = 73/262 (27%), Positives = 125/262 (47%), Gaps = 38/262 (14%) Query: 49 LIFAVSLLGNVCALVLVARRRRR--GATACLVLNLFCADLLFISA-IPLVLAVRWT-EAW 104 ++ V L+GN C LVLV R RR T L+ NL +D+L +A +PL LA + W Sbjct: 69 VVVVVGLVGN-CLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGW 127 Query: 105 LLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWG 164 + G CHL+F++ ++ V++ TL ++++R V +VH R R R A + IW Sbjct: 128 VFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLR--RRISLRLSAYAVLAIWA 185 Query: 165 YSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGE---ISWDVSFVTLNFLVPGL 221 SAV ALP V V + ++ +C W + + +W + VT +L+P L Sbjct: 186 LSAVLALPAAVHTYHVELK----PHDVRLCEEFWGSQERQRQLYAWGLLLVT--YLLPLL 239 Query: 222 VIVISYSKI-LQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFR 280 VI++SY ++ ++ ++ + ++ +A R+ R F Sbjct: 240 VILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRR---------------------RTFC 278 Query: 281 TLFLLMVSFFIMWSPIIITILL 302 L +++V F + W P+ + LL Sbjct: 279 LLVVVVVVFAVCWLPLHVFNLL 300 >gi|30581170 CC chemokine receptor 3 [Homo sapiens] Length = 355 Score = 81.6 bits (200), Expect = 1e-15 Identities = 81/319 (25%), Positives = 136/319 (42%), Gaps = 56/319 (17%) Query: 32 KGDHRLVLAAVETTVLVLIFAVSLLGNVCA-LVLVARRRRRGATACLVLNLFCADLLFIS 90 K D R ++A + L+F V LLGNV ++L+ RR R T +LNL +DLLF+ Sbjct: 26 KADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLV 85 Query: 91 AIPLVLAVRWTEAWLLGPVACHLL--FYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVR 148 +P + W+ G C LL FY L + + L ++++R + IVH +R Sbjct: 86 TLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIIL--LTIDRYLAIVHAVFALR 143 Query: 149 GPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWD 208 + + WG + +AALP +F+ E ++C+ ++P SW Sbjct: 144 ARTVTFGVITSIVTWGLAVLAALPEFIFYETEEL------FEETLCSALYPE-DTVYSWR 196 Query: 209 VSFVTLN-----FLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAY 263 F TL ++P LV+ I Y+ I++T LL Sbjct: 197 -HFHTLRMTIFCLVLPLLVMAICYTGIIKT---LLRC----------------------- 229 Query: 264 SESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILL-----ILIQNFKQDLVIWPSL 318 S++ ++ R +F++M FFI W+P + ILL IL N + + Sbjct: 230 -------PSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLV 282 Query: 319 FFWVVAFTFANSALNPILY 337 +++ +NP++Y Sbjct: 283 MLVTEVIAYSHCCMNPVIY 301 >gi|4502637 CC chemokine receptor 3 [Homo sapiens] Length = 355 Score = 81.6 bits (200), Expect = 1e-15 Identities = 81/319 (25%), Positives = 136/319 (42%), Gaps = 56/319 (17%) Query: 32 KGDHRLVLAAVETTVLVLIFAVSLLGNVCA-LVLVARRRRRGATACLVLNLFCADLLFIS 90 K D R ++A + L+F V LLGNV ++L+ RR R T +LNL +DLLF+ Sbjct: 26 KADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLV 85 Query: 91 AIPLVLAVRWTEAWLLGPVACHLL--FYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVR 148 +P + W+ G C LL FY L + + L ++++R + IVH +R Sbjct: 86 TLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIIL--LTIDRYLAIVHAVFALR 143 Query: 149 GPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWD 208 + + WG + +AALP +F+ E ++C+ ++P SW Sbjct: 144 ARTVTFGVITSIVTWGLAVLAALPEFIFYETEEL------FEETLCSALYPE-DTVYSWR 196 Query: 209 VSFVTLN-----FLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAY 263 F TL ++P LV+ I Y+ I++T LL Sbjct: 197 -HFHTLRMTIFCLVLPLLVMAICYTGIIKT---LLRC----------------------- 229 Query: 264 SESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILL-----ILIQNFKQDLVIWPSL 318 S++ ++ R +F++M FFI W+P + ILL IL N + + Sbjct: 230 -------PSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLV 282 Query: 319 FFWVVAFTFANSALNPILY 337 +++ +NP++Y Sbjct: 283 MLVTEVIAYSHCCMNPVIY 301 >gi|222080095 orexin receptor 1 [Homo sapiens] Length = 425 Score = 81.3 bits (199), Expect = 1e-15 Identities = 86/329 (26%), Positives = 143/329 (43%), Gaps = 31/329 (9%) Query: 48 VLIFAVSLLGNVCALVLVARRRR-RGATACLVLNLFCADLLFIS-AIPLVLAVRWTEAWL 105 V +F V+L+GN + V R R T ++NL AD+L + +P L V TE+WL Sbjct: 54 VAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWL 113 Query: 106 LGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGY 165 G C ++ Y+ +S SV +LTL+ ++L+R I H + RRAR +L IW Sbjct: 114 FGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICH-PLLFKSTARRARGSILG-IWAV 171 Query: 166 SAVAALPLCVFFR---VVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLV 222 S +P V+P+ L + S+C W + F + +L P + Sbjct: 172 SLAIMVPQAAVMECSSVLPE-LANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGL 230 Query: 223 IVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLF--- 279 + ++Y +I + L R + + + KR + L E Q R F Sbjct: 231 MAMAYFQIFRK----LWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAE 286 Query: 280 -----------RTLFLLMVSFFIMWSPI-IITILLILIQNFKQ--DLVIWPSLFFWVVAF 325 + L ++++ F + + PI ++ +L + F+Q D + F + Sbjct: 287 VKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWL 346 Query: 326 TFANSALNPILYNMT--LCRNEWKKIFCC 352 +ANSA NPI+YN R ++K F C Sbjct: 347 VYANSAANPIIYNFLSGKFREQFKAAFSC 375 >gi|4503905 galanin receptor 2 [Homo sapiens] Length = 387 Score = 81.3 bits (199), Expect = 1e-15 Identities = 75/302 (24%), Positives = 132/302 (43%), Gaps = 38/302 (12%) Query: 40 AAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACL-VLNLFCADLLFI-SAIPLVLA 97 A + + LIF V +GN L ++ R + +T L +LNL ADL FI +P Sbjct: 25 AVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQAT 84 Query: 98 VRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVH--LQRGVRGPGRRAR 155 + + W+ G + C + +++ L+ + TLAAVSL+R + I + R +R P R Sbjct: 85 IYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTP--RNA 142 Query: 156 AVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLN 215 + LIWG S + + P ++R +++C W + P + D+ + Sbjct: 143 LAAIGLIWGLSLLFSGPYLSYYR------QSQLANLTVCHPAW-SAPRRRAMDICTFVFS 195 Query: 216 FLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQD 275 +L+P LV+ ++Y++ L+ +D V S +A RK Sbjct: 196 YLLPVLVLGLTYARTLRYLWRAVD--PVAAGSGARRAKRK-------------------- 233 Query: 276 FRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPI 335 + R + ++ F + W P IL + F + +L ++ANS +NPI Sbjct: 234 --VTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATY-ALRILSHLVSYANSCVNPI 290 Query: 336 LY 337 +Y Sbjct: 291 VY 292 >gi|4502607 cholecystokinin A receptor [Homo sapiens] Length = 428 Score = 80.1 bits (196), Expect = 3e-15 Identities = 80/331 (24%), Positives = 142/331 (42%), Gaps = 36/331 (10%) Query: 41 AVETTVLVLIFAVSLLGNVCAL-VLVARRRRRGATACLVLNLFCADLLF-ISAIPLVLAV 98 AV+ + LIF +S+LGN + VL+ +R R T +L+L +DL+ + +P L Sbjct: 42 AVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIP 101 Query: 99 RWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVH-LQRGVRGPGRRARAV 157 + ++ G C Y M S SV+ L A+SLER I LQ V A V Sbjct: 102 NLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKV 161 Query: 158 LLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFL 217 + A W S P ++ +VP +Q ++C + P + SW + + FL Sbjct: 162 IAAT-WCLSFTIMTPYPIYSNLVPFT-KNNNQTANMCRFLLPNDVMQQSWHTFLLLILFL 219 Query: 218 VPGLVIVISYSKI-----------LQTSEHLLDARAVVTHS-----------EITKASRK 255 +PG+V++++Y I + + + T S + T+ RK Sbjct: 220 IPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRK 279 Query: 256 ---RLTVSLAYSESHQIRVSQQ------DFRLFRTLFLLMVSFFIMWSPIIITILLILIQ 306 R + + S +++IR + R+ R L +++V FF+ W PI Sbjct: 280 LELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYD 339 Query: 307 NFKQDLVIWPSLFFWVVAFTFANSALNPILY 337 + + + +++ ++ +S +NPI+Y Sbjct: 340 TASAERRLSGTPISFILLLSYTSSCVNPIIY 370 >gi|39725940 opioid receptor, kappa 1 [Homo sapiens] Length = 380 Score = 80.1 bits (196), Expect = 3e-15 Identities = 74/326 (22%), Positives = 142/326 (43%), Gaps = 40/326 (12%) Query: 39 LAAVETTVLVLIFAVSLLGNVCALVLVAR-RRRRGATACLVLNLFCADLLFISAIPLVLA 97 + + T V ++F V L+GN + ++ R + + AT + NL AD L + +P Sbjct: 58 IPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQST 117 Query: 98 VRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAV 157 V +W G V C ++ + + +I TL +S++R + + H + + + Sbjct: 118 VYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKI 177 Query: 158 LLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTL--- 214 + IW S+ + V + D ++ C+L +P + SW F+ + Sbjct: 178 INICIWLLSSSVGISAIVLGGTKVRE----DVDVIECSLQFP--DDDYSWWDLFMKICVF 231 Query: 215 --NFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVS 272 F++P L+I++ Y+ + +L ++V + SR++ +R Sbjct: 232 IFAFVIPVLIIIVCYTLM------ILRLKSV----RLLSGSREK---------DRNLR-- 270 Query: 273 QQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSAL 332 R+ R + +++ F + W+PI I IL+ + + S +F +A + NS+L Sbjct: 271 ----RITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYF-CIALGYTNSSL 325 Query: 333 NPILYNMTLCRNEWKKIFCCFWFPEK 358 NPILY +K+ F F FP K Sbjct: 326 NPILY--AFLDENFKRCFRDFCFPLK 349 >gi|170932505 neuromedin U receptor 2 [Homo sapiens] Length = 415 Score = 79.7 bits (195), Expect = 4e-15 Identities = 81/312 (25%), Positives = 139/312 (44%), Gaps = 47/312 (15%) Query: 44 TTVLVLIFAVSLLGNVCA-LVLVARRRRRGATACLVLNLFCADLL-FISAIPLVLAVRWT 101 + V V IF V ++GNV LV++ + + T + +L +DLL + +PL + W Sbjct: 49 SVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWR 108 Query: 102 E-AWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLA 160 +L GPV C+ + +IL++ VS+ER V I+H R RR +L Sbjct: 109 NYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILG 168 Query: 161 LIWGYSAVAALPLC----VFFRVVP--QRLPGADQEISICTLIWPTIPGEISWDVSFVT- 213 ++WG+S + +LP + F P +PG+ + CT+I P W +F+ Sbjct: 169 IVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGS----ATCTVIKP------MWIYNFIIQ 218 Query: 214 ----LNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQI 269 L +L+P VI + Y + + A ++ I + RK + Sbjct: 219 VTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRKSVN----------- 267 Query: 270 RVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLI-LIQNFKQDLVIWPSLFFWVV-AFTF 327 + LF+L++ F I W+P I L ++ + + L +L V F + Sbjct: 268 ----------KMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFY 317 Query: 328 ANSALNPILYNM 339 +SA+NPI+YN+ Sbjct: 318 LSSAVNPIIYNL 329 >gi|28875799 cholecystokinin B receptor [Homo sapiens] Length = 447 Score = 78.6 bits (192), Expect = 9e-15 Identities = 58/193 (30%), Positives = 96/193 (49%), Gaps = 9/193 (4%) Query: 41 AVETTVLVLIFAVSLLGNVCALVLVARRRR-RGATACLVLNLFCADLLF-ISAIPLVLAV 98 A+ T+ +IF +S+ GN+ +V++ RR R T +L+L +DLL ++ +P L Sbjct: 55 AIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLP 114 Query: 99 RWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVH-LQRGVRGPGRRARAV 157 ++ G V C + Y+M +S SV+ L+L A++LER I LQ V A V Sbjct: 115 NLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARV 174 Query: 158 LLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFL 217 ++A W S + +P V+ V P + C WP+ +W V + L F Sbjct: 175 IVA-TWLLSGLLMVPYPVYTVVQP-----VGPRVLQCVHRWPSARVRQTWSVLLLLLLFF 228 Query: 218 VPGLVIVISYSKI 230 +PG+V+ ++Y I Sbjct: 229 IPGVVMAVAYGLI 241 >gi|63477962 opioid receptor, delta 1 [Homo sapiens] Length = 372 Score = 77.8 bits (190), Expect = 1e-14 Identities = 82/312 (26%), Positives = 142/312 (45%), Gaps = 50/312 (16%) Query: 37 LVLAAVETTVLVLIFAVSLLGNVCALVLVAR-RRRRGATACLVLNLFCADLLFISAIPLV 95 L LA T + + AV LLGNV + + R + + AT + NL AD L S +P Sbjct: 46 LALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQ 105 Query: 96 LAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGV--RGPGRR 153 A E W G + C + + + +I TL +S++R + + H + + R P Sbjct: 106 SAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTP--- 162 Query: 154 ARAVLLAL-IWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFV 212 A+A L+ + IW ++ +P+ V P+ GA +C L +P+ SW V Sbjct: 163 AKAKLINICIWVLASGVGVPIMVMAVTRPR--DGA----VVCMLQFPSP----SWYWDTV 212 Query: 213 T------LNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSES 266 T F+VP L+I + Y +L L + +++ S+ S +R+T Sbjct: 213 TKICVFLFAFVVPILIITVCYGLMLLR----LRSVRLLSGSKEKDRSLRRIT-------- 260 Query: 267 HQIRVSQQDFRLFRTLFLLMVSFFIMWSPI-IITILLILIQNFKQDLVIWPSLFFWVVAF 325 R + +++ +F + W+PI I I+ L+ ++D ++ +L +A Sbjct: 261 -------------RMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHL-CIAL 306 Query: 326 TFANSALNPILY 337 +ANS+LNP+LY Sbjct: 307 GYANSSLNPVLY 318 >gi|88758590 G protein-coupled receptor 24 [Homo sapiens] Length = 422 Score = 77.4 bits (189), Expect = 2e-14 Identities = 68/311 (21%), Positives = 134/311 (43%), Gaps = 39/311 (12%) Query: 45 TVLVLIFAVSLLGNVCALVLVARRRR----RGATACLVLNLFCADLLFISAIPLVL-AVR 99 +V I + ++GN + V ++ + ++NL DLLF+ +P ++ + Sbjct: 114 SVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLM 173 Query: 100 WTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLL 159 W G C L+ + S + L A++++R + VH + +++ Sbjct: 174 GNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVI 233 Query: 160 ALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSF-VTLNFLV 218 L+W S ++ P+ ++ R++P PG C + P ++ W + L F + Sbjct: 234 CLLWALSFISITPVWLYARLIP--FPGGAVG---CGIRLPNPDTDLYWFTLYQFFLAFAL 288 Query: 219 PGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRL 278 P +VI +Y +ILQ R+T S+A + IR+ + R+ Sbjct: 289 PFVVITAAYVRILQ-----------------------RMTSSVAPASQRSIRLRTK--RV 323 Query: 279 FRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYN 338 RT + + FF+ W+P + L L + + + + L+ ++ +ANS LNP +Y Sbjct: 324 TRTAIAICLVFFVCWAPYYVLQLTQL--SISRPTLTFVYLYNAAISLGYANSCLNPFVY- 380 Query: 339 MTLCRNEWKKI 349 + LC K++ Sbjct: 381 IVLCETFRKRL 391 >gi|5174593 melatonin receptor 1A [Homo sapiens] Length = 350 Score = 77.0 bits (188), Expect = 3e-14 Identities = 80/318 (25%), Positives = 132/318 (41%), Gaps = 41/318 (12%) Query: 39 LAAVETTVLVLIFAVSLLGNVCALVLVARRRR-RGATACLVLNLFCADLLF-ISAIPLVL 96 LA+ VL+ V +LGN+ ++ V R ++ R A V++L ADL+ I PLVL Sbjct: 26 LASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVL 85 Query: 97 AVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARA 156 + W LG + C + ++M LS +I + +++ R I H + + + Sbjct: 86 MSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSL 145 Query: 157 VLLALIWGYSAVAALPLCVFFRVVPQRLPGA---DQEISICTLIWPTIPGEISWDVSFVT 213 + LIW L V+P G D I CT ++ ++ V Sbjct: 146 CYVLLIW---------LLTLAAVLPNLRAGTLQYDPRIYSCTFAQSV---SSAYTIAVVV 193 Query: 214 LNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQ 273 +FLVP ++++ Y +I V+ + K RK ++ Sbjct: 194 FHFLVPMIIVIFCYLRIWIL---------VLQVRQRVKPDRKP-------------KLKP 231 Query: 274 QDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALN 333 QDFR F T+F++ V F I W+P+ L + I LF + NS LN Sbjct: 232 QDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLN 291 Query: 334 PILYNM--TLCRNEWKKI 349 I+Y + R E+++I Sbjct: 292 AIIYGLLNQNFRKEYRRI 309 >gi|157738685 G protein-coupled receptor 103 [Homo sapiens] Length = 431 Score = 75.1 bits (183), Expect = 1e-13 Identities = 71/299 (23%), Positives = 133/299 (44%), Gaps = 28/299 (9%) Query: 48 VLIFAVSLLGNVCALVLVARRRR-RGATACLVLNLFCADLLF-ISAIPLVLAVRWTEAWL 105 VLIFA++L GN +V R + R T + +L +DLL IP+ + ++ WL Sbjct: 53 VLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWL 112 Query: 106 LGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGY 165 G C ++ +V + + ILT+ +++ER +VH + R +L ++W Sbjct: 113 GGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLV 172 Query: 166 SAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVI 225 + + P+ ++ + ++E C W + + + + + FL+P +V++I Sbjct: 173 AVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLI 232 Query: 226 SYSKI---LQTSEHLLDARAVVT--HSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFR 280 YSKI L + + D + T E++K +RK+ R Sbjct: 233 LYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKK-------------------RAVI 273 Query: 281 TLFLLMVSFFIMWSPIIITILLILIQNFKQ--DLVIWPSLFFWVVAFTFANSALNPILY 337 + ++ F + W+P + ++I NF++ D V +F V F+NS NPI+Y Sbjct: 274 MMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVY 332 >gi|66932941 XC chemokine receptor 1 [Homo sapiens] Length = 333 Score = 74.7 bits (182), Expect = 1e-13 Identities = 82/338 (24%), Positives = 142/338 (42%), Gaps = 78/338 (23%) Query: 38 VLAAVETTVLV-LIFAVSLLGNVCAL-VLVARRRRRGATACLVLNLFCADLLFISAIPLV 95 V A + TTVL L+F +SL+GN L VLV T +LNL +DL+F +P+ Sbjct: 28 VFATLATTVLYCLVFLLSLVGNSLVLWVLVKYESLESLTNIFILNLCLSDLVFACLLPVW 87 Query: 96 LA-VRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRA 154 ++ W W+LG C LL + ++S +I L +++ R + +V +R P R Sbjct: 88 ISPYHW--GWVLGDFLCKLLNMIFSISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRC 145 Query: 155 RAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFV-- 212 R ++ +W S ++++ +F +V+ G D E++W ++ V Sbjct: 146 RVLVTMAVWVASILSSILDTIFHKVLSS---GCDY-------------SELTWYLTSVYQ 189 Query: 213 -TLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRV 271 L FL+ +I+ Y +IL+T +++ R+ TV L Sbjct: 190 HNLFFLLSLGIILFCYVEILRTLFR-------------SRSKRRHRTVKL---------- 226 Query: 272 SQQDFRLFRTLFLLMVSFFIMWSPIIITILLILI------------QNFKQDLVIWPSLF 319 +F ++V++F+ W P T+ L + Q + L+I +L Sbjct: 227 ----------IFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNL- 275 Query: 320 FWVVAFTFANSALNPILYNM--TLCRNEWKKIFCCFWF 355 F++ NP+LY R K + FWF Sbjct: 276 ------AFSHCCFNPVLYVFVGVKFRTHLKHVLRQFWF 307 >gi|4885339 XC chemokine receptor 1 [Homo sapiens] Length = 333 Score = 74.7 bits (182), Expect = 1e-13 Identities = 82/338 (24%), Positives = 142/338 (42%), Gaps = 78/338 (23%) Query: 38 VLAAVETTVLV-LIFAVSLLGNVCAL-VLVARRRRRGATACLVLNLFCADLLFISAIPLV 95 V A + TTVL L+F +SL+GN L VLV T +LNL +DL+F +P+ Sbjct: 28 VFATLATTVLYCLVFLLSLVGNSLVLWVLVKYESLESLTNIFILNLCLSDLVFACLLPVW 87 Query: 96 LA-VRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRA 154 ++ W W+LG C LL + ++S +I L +++ R + +V +R P R Sbjct: 88 ISPYHW--GWVLGDFLCKLLNMIFSISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRC 145 Query: 155 RAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFV-- 212 R ++ +W S ++++ +F +V+ G D E++W ++ V Sbjct: 146 RVLVTMAVWVASILSSILDTIFHKVLSS---GCDY-------------SELTWYLTSVYQ 189 Query: 213 -TLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRV 271 L FL+ +I+ Y +IL+T +++ R+ TV L Sbjct: 190 HNLFFLLSLGIILFCYVEILRTLFR-------------SRSKRRHRTVKL---------- 226 Query: 272 SQQDFRLFRTLFLLMVSFFIMWSPIIITILLILI------------QNFKQDLVIWPSLF 319 +F ++V++F+ W P T+ L + Q + L+I +L Sbjct: 227 ----------IFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNL- 275 Query: 320 FWVVAFTFANSALNPILYNM--TLCRNEWKKIFCCFWF 355 F++ NP+LY R K + FWF Sbjct: 276 ------AFSHCCFNPVLYVFVGVKFRTHLKHVLRQFWF 307 >gi|4885057 apelin receptor [Homo sapiens] Length = 380 Score = 74.3 bits (181), Expect = 2e-13 Identities = 75/312 (24%), Positives = 131/312 (41%), Gaps = 46/312 (14%) Query: 41 AVETTVLVLIFAVSLLGNVCALVLVAR--RRRRGATACLVLNLFCADLLFISAIPLVLAV 98 A+ + +L+F + GN L V R R +R + + +L ADL F+ +PL Sbjct: 29 ALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATY 88 Query: 99 RWTEA-WLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAV 157 + + W G C L Y++ ++ ++ L +S +R + IV R R + AV Sbjct: 89 TYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAV 148 Query: 158 LLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWD----VSFVT 213 A++W +A+ A+P+ V R + + + T+ E +W+ VS T Sbjct: 149 ATAVLWVLAALLAMPVMV-LRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTT 207 Query: 214 LNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQ 273 + F+VP +++ Y I QT A E + RKR Sbjct: 208 VGFVVPFTIMLTCYFFIAQTI-------AGHFRKERIEGLRKRR---------------- 244 Query: 274 QDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWP--------SLFFWVVAF 325 RL + +L+V+F + W P + L ++ + L+ WP ++F + Sbjct: 245 ---RLLSIIVVLVVTFALCWMPYHLVKTLYMLGS----LLHWPCDFDLFLMNIFPYCTCI 297 Query: 326 TFANSALNPILY 337 ++ NS LNP LY Sbjct: 298 SYVNSCLNPFLY 309 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.331 0.141 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,776,405 Number of Sequences: 37866 Number of extensions: 499054 Number of successful extensions: 2305 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 159 Number of HSP's successfully gapped in prelim test: 232 Number of HSP's that attempted gapping in prelim test: 1712 Number of HSP's gapped (non-prelim): 503 length of query: 377 length of database: 18,247,518 effective HSP length: 104 effective length of query: 273 effective length of database: 14,309,454 effective search space: 3906480942 effective search space used: 3906480942 T: 11 A: 40 X1: 15 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.