BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55742695 sterile alpha motif domain containing 4B [Homo sapiens] (694 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55742695 sterile alpha motif domain containing 4B [Homo sapiens] 1403 0.0 gi|239582747 sterile alpha motif domain containing 4 isoform 1 [... 825 0.0 gi|239582749 sterile alpha motif domain containing 4 isoform 2 [... 617 e-177 gi|239582751 sterile alpha motif domain containing 4 isoform 3 [... 315 9e-86 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 49 2e-05 gi|21735419 zinc finger, CCHC domain containing 14 [Homo sapiens] 48 3e-05 gi|33356148 formin-like 1 [Homo sapiens] 45 2e-04 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 45 3e-04 gi|153792074 proline rich 12 [Homo sapiens] 45 3e-04 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 44 4e-04 gi|194248095 epsin 1 isoform b [Homo sapiens] 44 5e-04 gi|52485606 formin-like 2 [Homo sapiens] 44 7e-04 gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 43 0.001 gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 42 0.001 gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 42 0.001 gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 42 0.003 gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 42 0.003 gi|41350201 epsin 1 isoform c [Homo sapiens] 42 0.003 gi|194272148 epsin 1 isoform a [Homo sapiens] 42 0.003 gi|112421108 capicua homolog [Homo sapiens] 41 0.003 gi|24497513 homeobox A3 isoform a [Homo sapiens] 41 0.004 gi|13562112 homeobox A3 isoform a [Homo sapiens] 41 0.004 gi|56682953 epidermal growth factor receptor pathway substrate 8... 41 0.004 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 40 0.006 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 40 0.006 gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 40 0.006 gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens] 40 0.006 gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens] 40 0.006 gi|4507691 transformation/transcription domain-associated protei... 40 0.006 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 40 0.006 >gi|55742695 sterile alpha motif domain containing 4B [Homo sapiens] Length = 694 Score = 1403 bits (3632), Expect = 0.0 Identities = 694/694 (100%), Positives = 694/694 (100%) Query: 1 MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLES 60 MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLES Sbjct: 1 MMFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLES 60 Query: 61 EANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIE 120 EANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIE Sbjct: 61 EANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIE 120 Query: 121 ESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAE 180 ESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAE Sbjct: 121 ESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAE 180 Query: 181 LGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQIHPSPLKRSMSLI 240 LGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQIHPSPLKRSMSLI Sbjct: 181 LGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQIHPSPLKRSMSLI 240 Query: 241 PTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSG 300 PTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSG Sbjct: 241 PTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSG 300 Query: 301 MKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQ 360 MKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQ Sbjct: 301 MKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQ 360 Query: 361 SVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPL 420 SVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPL Sbjct: 361 SVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPL 420 Query: 421 PGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMG 480 PGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMG Sbjct: 421 PGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMG 480 Query: 481 KVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAAL 540 KVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAAL Sbjct: 481 KVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAAL 540 Query: 541 EMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVS 600 EMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVS Sbjct: 541 EMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVS 600 Query: 601 PRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCP 660 PRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCP Sbjct: 601 PRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCP 660 Query: 661 VPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI 694 VPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI Sbjct: 661 VPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI 694 >gi|239582747 sterile alpha motif domain containing 4 isoform 1 [Homo sapiens] Length = 717 Score = 825 bits (2132), Expect = 0.0 Identities = 448/730 (61%), Positives = 535/730 (73%), Gaps = 50/730 (6%) Query: 2 MFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESE 61 MFRDQVG+LAGWFKGWNECEQTVALLSLLKRV++TQARFLQLCLEHSLADC ++H+LE E Sbjct: 1 MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE 60 Query: 62 ANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEE 121 ANS I++QWQQESK+KV+SLLL+HLPLL+PGN +AK EYM+LL K+LA+SIE N IEE Sbjct: 61 ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEE 120 Query: 122 SRQLLSYALIHPATTLEDRNALALWLSHLEERLASGF----RSRPEP-------SYHSRQ 170 SRQLLSYALIHPAT+LEDR+ALA+WL+HLE+R ++ F R R + YH RQ Sbjct: 121 SRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQ 180 Query: 171 GSDE----WGGPAELGPGEAGPGWQDKPPR-ENGHVPFHPSSSVPPAINSIGSNANTGLP 225 SD+ W + G WQDK ENGHVP + SSSVP IN+IG++ +T L Sbjct: 181 NSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTILS 240 Query: 226 CQIHPSPLKRSMSLIPTSPQVPGE-----WPSPEELGARAAFTTP-DHAPLSPQSSVASS 279 Q H SPLKRS+SL P VP + W S E+L AR P DHAPLSPQSSVASS Sbjct: 241 GQAHHSPLKRSVSLTPPM-NVPNQPLGHGWMSHEDLRARGPQCLPSDHAPLSPQSSVASS 299 Query: 280 ---GSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHL 336 GSE E+Q ++RNTFQE+GSGMKDVP+WLKSLRLHKYAALFSQM+YEEMM LTE L Sbjct: 300 GSGGSEHLEDQTTARNTFQEEGSGMKDVPAWLKSLRLHKYAALFSQMTYEEMMALTECQL 359 Query: 337 ESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSV 396 E+QNVTKGARHKI +SIQKL+ERQ++LKSLE+D++EGG+LR LQEL Q+I+TPIKAYS Sbjct: 360 EAQNVTKGARHKIVISIQKLKERQNLLKSLERDIIEGGSLRIPLQELHQMILTPIKAYS- 418 Query: 397 LQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPT 456 + +TTP A+ P P P P + + KD A P+ + Sbjct: 419 ------SPSTTPEARRREPQAPRQPSLMGP-----ESQSPDCKDGAAATGATATPSAGAS 467 Query: 457 DGSEP----------APAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKC 506 G +P A AP+ +GD+P QFTRVMGKVCTQLLVSRPDEENI+SYLQLI+KC Sbjct: 468 GGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKC 527 Query: 507 LTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFG-SNSLPIAGSVG 565 L HEAFTETQKKRLLSWKQQV KL R+FPRK L++ YRQQ+ FG SNSLP AGSVG Sbjct: 528 LIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGSVG 587 Query: 566 MGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGG 625 G+ RR RQ+ +P R +P R+GLL SG + R+ +P++ QGRQNLWFANPGG Sbjct: 588 GGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGG 647 Query: 626 SNSMPSQSRSSVQRTHSLPVHSSPQAILMF-PPDCPVPGPDLEINPTLESLCLSMTEHAL 684 SNSMPS++ SSVQRT SLPVH+SPQ +LMF P+ +P + +IN LESLCLSMTEHAL Sbjct: 648 SNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPVTEPDINNRLESLCLSMTEHAL 707 Query: 685 GDGTDKTSTI 694 GDG D+TSTI Sbjct: 708 GDGVDRTSTI 717 >gi|239582749 sterile alpha motif domain containing 4 isoform 2 [Homo sapiens] Length = 629 Score = 617 bits (1592), Expect = e-177 Identities = 359/709 (50%), Positives = 443/709 (62%), Gaps = 96/709 (13%) Query: 2 MFRDQVGILAGWFKGWNECEQTVALLSLLKRVTRTQARFLQLCLEHSLADCNDIHLLESE 61 MFRDQVG+LAGWFKGWNECEQTVALLSLLKRV++TQARFLQLCLEHSLADC ++H+LE E Sbjct: 1 MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLERE 60 Query: 62 ANSAAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEE 121 ANS I++QWQQESK+KV+SLLL+HLPLL+PGN +AK EYM+LL K+L Sbjct: 61 ANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKIL------------ 108 Query: 122 SRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAE- 180 ++++ H E R L+ L H P S R W E Sbjct: 109 -----AHSIEHNQHIEESRQLLSYALIH------------PATSLEDRSALAMWLNHLED 151 Query: 181 ---LGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQIHPSPLKRSM 237 G G D H +H + +N ++ ++G+ Sbjct: 152 RTSTSFGGQNRGRSDSVDYGQTHY-YHQRQNSDDKLNGWQNSRDSGICINA--------- 201 Query: 238 SLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQED 297 W + +G H PL SSV ++ G+S +T Sbjct: 202 ----------SNWQD-KSMGCENG-----HVPLYSSSSVPTT----INTIGTSTST---- 237 Query: 298 GSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLR 357 +VP+WLKSLRLHKYAALFSQM+YEEMM LTE LE+QNVTKGARHKI +SIQKL+ Sbjct: 238 -----NVPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLK 292 Query: 358 ERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGE 417 ERQ++LKSLE+D++EGG+LR LQEL Q+I+TPIKAYS + +TTP A+ P Sbjct: 293 ERQNLLKSLERDIIEGGSLRIPLQELHQMILTPIKAYS-------SPSTTPEARRREPQA 345 Query: 418 PPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEP----------APAPVA 467 P P P + + KD A P+ + G +P A AP+ Sbjct: 346 PRQPSLMGP-----ESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLP 400 Query: 468 DGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQV 527 +GD+P QFTRVMGKVCTQLLVSRPDEENI+SYLQLI+KCL HEAFTETQKKRLLSWKQQV Sbjct: 401 EGDLPGQFTRVMGKVCTQLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQV 460 Query: 528 LKLLRTFPRKAALEMQNYRQQKGWAFG-SNSLPIAGSVGMGVARRTQRQFPMPPRALPPG 586 KL R+FPRK L++ YRQQ+ FG SNSLP AGSVG G+ RR RQ+ +P R +P Sbjct: 461 QKLFRSFPRKTLLDISGYRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSA 520 Query: 587 RMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVH 646 R+GLL SG + R+ +P++ QGRQNLWFANPGGSNSMPS++ SSVQRT SLPVH Sbjct: 521 RLGLLGTSGFVSSNQRNTTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVH 580 Query: 647 SSPQAILMF-PPDCPVPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI 694 +SPQ +LMF P+ +P + +IN LESLCLSMTEHALGDG D+TSTI Sbjct: 581 TSPQNMLMFQQPEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI 629 >gi|239582751 sterile alpha motif domain containing 4 isoform 3 [Homo sapiens] Length = 345 Score = 315 bits (807), Expect = 9e-86 Identities = 181/357 (50%), Positives = 218/357 (61%), Gaps = 60/357 (16%) Query: 386 IIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVE 445 +I+TPIKAYS + +TTP A+ P P P P + + KD A Sbjct: 1 MILTPIKAYS-------SPSTTPEARRREPQAPRQPSLMGP-----ESQSPDCKDGAAAT 48 Query: 446 NYPPPPAPAPTDGSEP----------APAPVADGDIPSQFTRVMGKVCTQLLVSRPDEEN 495 P+ + G +P A AP+ +GD+P QFTRVMGKVCTQLLVSRPDEEN Sbjct: 49 GATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQLLVSRPDEEN 108 Query: 496 ITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFG- 554 I+SYLQLI+KCL HEAFTETQKKRLLSWKQQV KL R+FPRK L++ YRQQ+ FG Sbjct: 109 ISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYRQQRNRGFGQ 168 Query: 555 SNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGGQG 614 SNSLP AGSVG G+ RR RQ+ +P R +P R+GLL SG + R+ +P++ QG Sbjct: 169 SNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTTATPTIMKQG 228 Query: 615 RQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMF------------------- 655 RQNLWFANPGGSNSMPS++ SSVQRT SLPVH+SPQ +LMF Sbjct: 229 RQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPGSQVHSGLCLTDLRGW 288 Query: 656 -----PPDCP-------------VPGPDLEINPTLESLCLSMTEHALGDGTDKTSTI 694 P P +P + +IN LESLCLSMTEHALGDG D+TSTI Sbjct: 289 LSLSGAPSMPALTVPKSSQGEFQLPVTEPDINNRLESLCLSMTEHALGDGVDRTSTI 345 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 48.9 bits (115), Expect = 2e-05 Identities = 72/302 (23%), Positives = 114/302 (37%), Gaps = 28/302 (9%) Query: 343 KGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVA 402 K + +I+L++++ R R+ + ++ L+ L + P K A Sbjct: 454 KQSSSEISLAVERARRRREEEERRMQEERRAA-CAEKLKRLDEKFGAPDKRLKAEPAAPP 512 Query: 403 AATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPA 462 AA +TP P E P P A PP + P + TE ++P PP PT G A Sbjct: 513 AAPSTPAPPPAVPKELPAPPAPPPASAPTPE--TEPEEPAQA----PPAQSTPTPGVAAA 566 Query: 463 PAPVADGDIPS-------QFTRVMGKVCTQLLVSRPDE--ENITSYLQLIEKCLTHEAFT 513 P V+ G S + + V ++ ++ P+E T + +E T Sbjct: 567 PTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPT 626 Query: 514 ETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGW----AFGSNSLPIAGS----VG 565 + L + + L F R+ ++ +QQ W + P+ S V Sbjct: 627 RQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVT 686 Query: 566 MGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGG---QGRQNLWFAN 622 +G Q P PP+AL PG +G P PR + P + QGR L F Sbjct: 687 LGAVPAPQAP-PPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP 745 Query: 623 PG 624 PG Sbjct: 746 PG 747 Score = 31.6 bits (70), Expect = 2.6 Identities = 35/141 (24%), Positives = 50/141 (35%), Gaps = 34/141 (24%) Query: 157 GFRSRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPSSS------VP 210 G RSR SY +G D GG G G + PP G S +P Sbjct: 1048 GARSREFRSYREFRGDDGRGG---------GTGGPNHPPAPRGRTASETRSEGSEYEEIP 1098 Query: 211 PAINSIGSNANTGLPCQIH-----------PSPLKRSMSLIPTSPQVPGEWPSPEELGAR 259 GS + + H P+P + +++ +P +P PG PSP A Sbjct: 1099 KRRRQRGSETGS----ETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSP----AP 1150 Query: 260 AAFTTPDHAPLSPQSSVASSG 280 A FT +P+ + G Sbjct: 1151 ARFTARGGRVFTPRGVPSRRG 1171 Score = 30.0 bits (66), Expect = 7.5 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 10/59 (16%) Query: 412 DGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTD-------GSEPAP 463 + P E P PG+EPP P + K+ P P PP P T+ G+EP P Sbjct: 1694 NAVPCEGP-PGSEPPRRPPPAPHDGDRKELP--REQPLPPGPIGTERSQRTDRGTEPGP 1749 >gi|21735419 zinc finger, CCHC domain containing 14 [Homo sapiens] Length = 949 Score = 48.1 bits (113), Expect = 3e-05 Identities = 45/151 (29%), Positives = 71/151 (47%), Gaps = 25/151 (16%) Query: 230 PSPLKRSMSLIPTSPQVPGEWPSPEELGARAAFTTPDH---------APLSPQSSVASSG 280 PSP S+S + T V G P G ++ + H APL S S+G Sbjct: 211 PSPGNPSLSKVGTVMGVSGR-PVCGVAGIPSSQSGAQHHGQHPAGSAAPLPHCSHAGSAG 269 Query: 281 SEQTEE----------QGSSRNTFQ-EDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMM 329 S SS T Q ++ +G+ D WL+ LRLHKY +F Q+S E+ + Sbjct: 270 SALAYRTQMDTSPAILMPSSLQTPQTQEQNGILD---WLRKLRLHKYYPVFKQLSMEKFL 326 Query: 330 TLTEQHLES-QNVTKGARHKIALSIQKLRER 359 +LTE+ L +++T GA+ K+ ++ +E+ Sbjct: 327 SLTEEDLNKFESLTMGAKKKLKTQLELEKEK 357 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 45.4 bits (106), Expect = 2e-04 Identities = 47/175 (26%), Positives = 68/175 (38%), Gaps = 31/175 (17%) Query: 315 KYAALFSQMSY--EEMMTLTEQHLESQNVTKGAR---------------HKIALSIQKLR 357 K A L Q+S +E+ TL E+ ES + R + L +++L Sbjct: 425 KIAELEKQLSQARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELE 484 Query: 358 ERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGE 417 E+ + +L G +++ L + TP S A T + D AP Sbjct: 485 EKGLIR------ILRGPGDAVSIEILPVAVATP----SGGDAPTPGVPTGSPSPDLAPAA 534 Query: 418 PPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIP 472 P PGA PP P + + PP+ PP AP EP PAP GD+P Sbjct: 535 EPAPGAAPPPPPPLPGLPSPQEAPPSA----PPQAPPLPGSPEPPPAPPLPGDLP 585 Score = 41.6 bits (96), Expect = 0.003 Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 11/130 (8%) Query: 403 AATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAP----TDG 458 AA P G P P + PP A P PP + PPPP P P TDG Sbjct: 540 AAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDG 599 Query: 459 ---SEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEEN----ITSYLQLIEKCLTHEA 511 P P P G P R ++ + +P + + +++ L +T Sbjct: 600 PVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTV 659 Query: 512 FTETQKKRLL 521 FTE +++L Sbjct: 660 FTELNDEKVL 669 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 44.7 bits (104), Expect = 3e-04 Identities = 72/299 (24%), Positives = 116/299 (38%), Gaps = 51/299 (17%) Query: 195 PRENGHVPFHPSSSVP-PAINSIGSNANTGLPCQIHPSPLKRSMSLI--PTSPQVPGEWP 251 P E G H + S+ ++ S ++ L Q LKRS+ + PT P++ G Sbjct: 1304 PTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPEL-GLPD 1362 Query: 252 SP-------EELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQE--DGSGMK 302 SP +E+ A P H P+ SSG +T QE G+G+ Sbjct: 1363 SPSNLLRFIQEVHAHYLHQRPLHTPIIVH---CSSGVGRTGAFALLYAAVQEVEAGNGIP 1419 Query: 303 DVPSWLKSLRLHKYAALFSQMS----YEEMMTLTEQHLESQNVTKGARHKIALSIQKLRE 358 ++P ++ +R + L ++ YE ++ EQ L+ V + + SI + Sbjct: 1420 ELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQ--- 1476 Query: 359 RQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPG-- 416 ++ L +D++ GG++ PI S +QAT+A + P PG Sbjct: 1477 -KNHLPQDSQDLVLGGDV-------------PI---SSIQATIAKLSIRP------PGGL 1513 Query: 417 EPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPP---PAPAPTDGSEPAPAPVADGDIP 472 E P+ P PG + + P + PPP P P E P P A P Sbjct: 1514 ESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGP 1572 Score = 32.3 bits (72), Expect = 1.5 Identities = 27/76 (35%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Query: 417 EPPLPGAEPPLAHPGTDKGTEAKDP-PAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQF 475 +P + G PP H G A+DP PA P P+P P +P P+A G PS Sbjct: 1003 QPGVLGQPPPPLHTQLYPGP-AQDPLPAHSGALPFPSPGPP---QPPHPPLAYGPAPS-- 1056 Query: 476 TRVMGKVCTQLLVSRP 491 TR MG L + P Sbjct: 1057 TRPMGPQAAPLTIRGP 1072 Score = 29.6 bits (65), Expect = 9.8 Identities = 25/89 (28%), Positives = 31/89 (34%), Gaps = 9/89 (10%) Query: 408 PTAKDGAPGEPPL-PGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPV 466 P A AP P+ P A P + G P V + P P P P PA P Sbjct: 1048 PLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEP- 1106 Query: 467 ADGDIPSQFTRVMGKVCTQLLVSRPDEEN 495 P R G LL S P+ ++ Sbjct: 1107 -----PPCLRR--GAAAADLLSSSPESQH 1128 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 44.7 bits (104), Expect = 3e-04 Identities = 42/135 (31%), Positives = 56/135 (41%), Gaps = 16/135 (11%) Query: 337 ESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSV 396 ES+ + G ++L+ L S D E +N ++LQ+ I + I A Sbjct: 1351 ESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDE-EDSVAKN--RDLQESISSAISALDD 1407 Query: 397 LQATVAAATTTPTAKDGAP-----GEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPP- 450 T+TP AP G PPLPG P GT +PP +E PPP Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGL-PSANSNGTP------EPPLLEEKPPPT 1460 Query: 451 PAPAPTDGSEPAPAP 465 P PAPT +P P P Sbjct: 1461 PPPAPTPQPQPPPPP 1475 Score = 37.7 bits (86), Expect = 0.036 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 8/64 (12%) Query: 407 TPTAKDGAPGEPPLPG--AEPPLAHPGTDKGTEAKDPPAVENYPPPPA-PAPTDGSEPAP 463 TP + P PP P + PPL P T + PP PPPPA P+P PA Sbjct: 1466 TPQPQPPPPPPPPQPALPSPPPLVAP-----TPSSPPPPPLPPPPPPAMPSPPPPPPPAA 1520 Query: 464 APVA 467 AP+A Sbjct: 1521 APLA 1524 Score = 35.4 bits (80), Expect = 0.18 Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 4/60 (6%) Query: 408 PTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYP----PPPAPAPTDGSEPAP 463 P+A EPPL +PP P PP P PPP APT S P P Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP 1499 Score = 33.9 bits (76), Expect = 0.52 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 11/64 (17%) Query: 408 PTAKDGAPGEPPL----PGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAP 463 P + P PPL P + PP P PPA+ + PPPP PA + P Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLP-------PPPPPAMPSPPPPPPPAAAPLAAPPE 1528 Query: 464 APVA 467 P A Sbjct: 1529 EPAA 1532 Score = 32.3 bits (72), Expect = 1.5 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 5/56 (8%) Query: 415 PGEPPLPGAEP-PLAHPGTDKGTEAKDPPAV----ENYPPPPAPAPTDGSEPAPAP 465 P PP P +P P P + PP V + PPPP P P + P+P P Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPP 1514 Score = 30.8 bits (68), Expect = 4.4 Identities = 26/87 (29%), Positives = 34/87 (39%), Gaps = 30/87 (34%) Query: 408 PTAKDGAPGEPPLPGAEPP---------LAHPGTD--------KGTEAKDPP-------- 442 P +DGAP PP P PP L G + + E+ DPP Sbjct: 826 PATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLG 885 Query: 443 AVENYPPPP-----APAPTDGSEPAPA 464 A+E PP P P ++G +PA A Sbjct: 886 ALEPLPPAPGDTGVGPPNSEGKDPAGA 912 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 44.3 bits (103), Expect = 4e-04 Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 415 PGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPS 473 P PP G PL P G PP PPPP P P+ G+ PAP P+ +P+ Sbjct: 369 PPPPPATGRSGPLPPPPPGAGGPPMPPP-----PPPPPPPPSSGNGPAPPPLPPALVPA 422 >gi|194248095 epsin 1 isoform b [Homo sapiens] Length = 576 Score = 43.9 bits (102), Expect = 5e-04 Identities = 35/150 (23%), Positives = 61/150 (40%), Gaps = 22/150 (14%) Query: 333 EQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIK 392 E+H + + + +G ++ ++I++ + GG ++L +L + P Sbjct: 222 EEHDKEERIRRGDDLRLQMAIEESKRET------------GGKEESSLMDLADVFTAPAP 269 Query: 393 AYSVLQ----ATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGT------EAKDPP 442 A + A +AAA T G PP+P A P P + A P Sbjct: 270 APTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGP 329 Query: 443 AVENYPPPPAPAPTDGSEPAPAPVADGDIP 472 +V+ + PAPA +G P P +DG +P Sbjct: 330 SVDPWGGTPAPAAGEGPTPDPWGSSDGGVP 359 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 43.5 bits (101), Expect = 7e-04 Identities = 36/146 (24%), Positives = 54/146 (36%), Gaps = 5/146 (3%) Query: 323 MSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQE 382 M + + + + + N K+ ++ +RQS L+ ++ + G ++ + Sbjct: 428 MQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKG 487 Query: 383 LQQIIITPIKAYSVLQA---TVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAK 439 I I P+ A L VA + PT GA PLP PPL T Sbjct: 488 DGDIAILPVVASGTLSMGSEVVAGNSVGPTM--GAASSGPLPPPPPPLPPSSDTPETVQN 545 Query: 440 DPPAVENYPPPPAPAPTDGSEPAPAP 465 P PPPP P P P P P Sbjct: 546 GPVTPPMPPPPPPPPPPPPPPPPPPP 571 Score = 34.7 bits (78), Expect = 0.31 Identities = 19/63 (30%), Positives = 23/63 (36%), Gaps = 3/63 (4%) Query: 404 ATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDP---PAVENYPPPPAPAPTDGSE 460 ++ TP P PP+P PP P P PA E P PP P + Sbjct: 536 SSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAP 595 Query: 461 PAP 463 P P Sbjct: 596 PLP 598 Score = 30.8 bits (68), Expect = 4.4 Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 1/70 (1%) Query: 390 PIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPP 449 P+ S TV TP P PP P PP P G A+ PA PP Sbjct: 532 PLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLP-GPAAETVPAPPLAPP 590 Query: 450 PPAPAPTDGS 459 P+ P G+ Sbjct: 591 LPSAPPLPGT 600 >gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] Length = 825 Score = 42.7 bits (99), Expect = 0.001 Identities = 79/337 (23%), Positives = 117/337 (34%), Gaps = 58/337 (17%) Query: 179 AELGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQIHPSPLKRSMS 238 AE+ P A ++PP E P S SV + I S + P ++ P P + ++ Sbjct: 348 AEILPPSAEESPSEEPPAEILPPPAEKSPSVE-LLGEIRSPSAQKAPIEVQPLPAEGALE 406 Query: 239 LIPTS--------------PQVPGEWPSPE--ELGARAAFTTP-DHAPLSPQSSVASSGS 281 P P +P E P E EL A TP + AP QS + Sbjct: 407 EAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPK--- 463 Query: 282 EQTEEQGSSR-NTFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQN 340 E T E+ S+ + P+ +S L + S EE + L + Sbjct: 464 ETTAEEASAEIQLLAATEPPADETPAEARS-------PLSEETSAEEAHAEVQSPLAEET 516 Query: 341 VTKGARHKIAL-------SIQKLRERQSVLKS----------LEKDVLEGGNLRNALQEL 383 + A +I L + + E QS L ++ +G ++ A EL Sbjct: 517 TAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLEL 576 Query: 384 QQ------IIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTE 437 Q A +L AT A+A P P E +PP P + E Sbjct: 577 QPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPP---PAEEAPAE 633 Query: 438 AKDPPAVE---NYPPPPAPAPTDGSEPAPAPVADGDI 471 + PPA E PPPA +P PA A ++ Sbjct: 634 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 670 >gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2 [Homo sapiens] Length = 1481 Score = 42.4 bits (98), Expect = 0.001 Identities = 75/325 (23%), Positives = 120/325 (36%), Gaps = 51/325 (15%) Query: 160 SRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPSS---SVPPAINSI 216 SR S + R GS P+ G + + K +P S S PA + Sbjct: 306 SRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRH 365 Query: 217 GSNANTGLPCQIHPSPLKRSMSLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSV 276 S+ S KRS S S P P LGA + + A ++ Sbjct: 366 SSSH----------SKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERA-----AAA 410 Query: 277 ASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHL 336 A++ + E +GS +++ S ++ S L+S +L + L E++ +T + Sbjct: 411 AAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNT 470 Query: 337 ESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSV 396 E +N + + K+ + +K L KD+ G + L++ I+TP + Sbjct: 471 EVKNSSDTGKVKLDENSEK---------HLVKDLKAQGTRDSKPIALKEEIVTPKE---- 517 Query: 397 LQATVAAATTTPTAKDGAPGEPPLPG-AEPPLAHPGTDKGTEAKDPPAVENYPP-PPAPA 454 T T++ P PPLP A PP P T PP PP PP PA Sbjct: 518 ----------TETSEKETP--PPLPTIASPPPPLPTTTP------PPQTPPLPPLPPIPA 559 Query: 455 PTDGSEPAPAPVADGDIPSQFTRVM 479 P+ A +P+ T + Sbjct: 560 LPQQPPLPPSQPAFSQVPASSTSTL 584 Score = 32.0 bits (71), Expect = 2.0 Identities = 39/195 (20%), Positives = 73/195 (37%), Gaps = 27/195 (13%) Query: 304 VPSWLKSLRLHKYAALFSQMSY--EEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQS 361 +P + L +H + Q+ + + LTE + Q+ A + S+++ Sbjct: 1131 IPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEE---SLKEAPSAPV 1187 Query: 362 VLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLP 421 +L S E+ LE + +Q + ++++ + Q + + K+ P P Sbjct: 1188 ILPSAEQTTLEASSTPADMQNILAVLLSQLMK---TQEPAGSLEENNSDKNSGPQGPRRT 1244 Query: 422 GAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMGK 481 P + K PP PPP P P P+ +GD+ S + Sbjct: 1245 PTMP-------QEEAAEKRPPEPPGPPPP----------PPPPPLVEGDLSSAPQELNPA 1287 Query: 482 VCTQL--LVSRPDEE 494 V L L+S+P+ E Sbjct: 1288 VTAALLQLLSQPEAE 1302 >gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1 [Homo sapiens] Length = 1490 Score = 42.4 bits (98), Expect = 0.001 Identities = 75/325 (23%), Positives = 120/325 (36%), Gaps = 51/325 (15%) Query: 160 SRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPSS---SVPPAINSI 216 SR S + R GS P+ G + + K +P S S PA + Sbjct: 306 SRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRH 365 Query: 217 GSNANTGLPCQIHPSPLKRSMSLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSV 276 S+ S KRS S S P P LGA + + A ++ Sbjct: 366 SSSH----------SKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERA-----AAA 410 Query: 277 ASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHL 336 A++ + E +GS +++ S ++ S L+S +L + L E++ +T + Sbjct: 411 AAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNT 470 Query: 337 ESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSV 396 E +N + + K+ + +K L KD+ G + L++ I+TP + Sbjct: 471 EVKNSSDTGKVKLDENSEK---------HLVKDLKAQGTRDSKPIALKEEIVTPKE---- 517 Query: 397 LQATVAAATTTPTAKDGAPGEPPLPG-AEPPLAHPGTDKGTEAKDPPAVENYPP-PPAPA 454 T T++ P PPLP A PP P T PP PP PP PA Sbjct: 518 ----------TETSEKETP--PPLPTIASPPPPLPTTTP------PPQTPPLPPLPPIPA 559 Query: 455 PTDGSEPAPAPVADGDIPSQFTRVM 479 P+ A +P+ T + Sbjct: 560 LPQQPPLPPSQPAFSQVPASSTSTL 584 Score = 33.9 bits (76), Expect = 0.52 Identities = 40/195 (20%), Positives = 74/195 (37%), Gaps = 18/195 (9%) Query: 304 VPSWLKSLRLHKYAALFSQMSY--EEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQS 361 +P + L +H + Q+ + + LTE + Q+ A + S+++ Sbjct: 1131 IPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEE---SLKEAPSAPV 1187 Query: 362 VLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLP 421 +L S E+ LE + +Q + ++++ + ++ + + P P Sbjct: 1188 ILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTM 1247 Query: 422 GAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMGK 481 E A P E K PP PPP P P P+ +GD+ S + Sbjct: 1248 PQEEAAACPPHILPPE-KRPPEPPGPPPP----------PPPPPLVEGDLSSAPQELNPA 1296 Query: 482 VCTQL--LVSRPDEE 494 V L L+S+P+ E Sbjct: 1297 VTAALLQLLSQPEAE 1311 >gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] Length = 1096 Score = 41.6 bits (96), Expect = 0.003 Identities = 41/154 (26%), Positives = 59/154 (38%), Gaps = 15/154 (9%) Query: 325 YEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQ 384 Y + + + HL V K K+ S QK E K +++ + LQ+ Sbjct: 469 YRQRLDIDLTHLIDSCVNKA---KVEESEQKAAEFS---KKFDEEFTARQEAQAELQKRD 522 Query: 385 QIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPP-- 442 + I ++A T A ++ + G P PPLPG PP P A PP Sbjct: 523 EKI-KELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPP 581 Query: 443 ----AVENYPPPPAPAPTDGSEPAPAPVADGDIP 472 + PPPP P G P P P+ G +P Sbjct: 582 PPLPGMMGIPPPPPPPLLFGGPPPPPPL--GGVP 613 >gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] Length = 1101 Score = 41.6 bits (96), Expect = 0.003 Identities = 41/154 (26%), Positives = 59/154 (38%), Gaps = 15/154 (9%) Query: 325 YEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQ 384 Y + + + HL V K K+ S QK E K +++ + LQ+ Sbjct: 469 YRQRLDIDLTHLIDSCVNKA---KVEESEQKAAEFS---KKFDEEFTARQEAQAELQKRD 522 Query: 385 QIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPP-- 442 + I ++A T A ++ + G P PPLPG PP P A PP Sbjct: 523 EKI-KELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPP 581 Query: 443 ----AVENYPPPPAPAPTDGSEPAPAPVADGDIP 472 + PPPP P G P P P+ G +P Sbjct: 582 PPLPGMMGIPPPPPPPLLFGGPPPPPPL--GGVP 613 >gi|41350201 epsin 1 isoform c [Homo sapiens] Length = 550 Score = 41.6 bits (96), Expect = 0.003 Identities = 31/110 (28%), Positives = 45/110 (40%), Gaps = 10/110 (9%) Query: 373 GGNLRNALQELQQIIITPIKAYSVLQ----ATVAAATTTPTAKDGAPGEPPLPGAEPPLA 428 GG ++L +L + P A + A +AAA T G PP+P A P Sbjct: 225 GGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWG 284 Query: 429 HPGTDKGT------EAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIP 472 P + A P+V+ + PAPA +G P P +DG +P Sbjct: 285 GPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVP 334 >gi|194272148 epsin 1 isoform a [Homo sapiens] Length = 662 Score = 41.6 bits (96), Expect = 0.003 Identities = 31/110 (28%), Positives = 45/110 (40%), Gaps = 10/110 (9%) Query: 373 GGNLRNALQELQQIIITPIKAYSVLQ----ATVAAATTTPTAKDGAPGEPPLPGAEPPLA 428 GG ++L +L + P A + A +AAA T G PP+P A P Sbjct: 336 GGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWG 395 Query: 429 HPGTDKGT------EAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIP 472 P + A P+V+ + PAPA +G P P +DG +P Sbjct: 396 GPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVP 445 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 41.2 bits (95), Expect = 0.003 Identities = 70/314 (22%), Positives = 105/314 (33%), Gaps = 53/314 (16%) Query: 199 GHVPFHPSSSVPPAINSIGSN-----------------ANTGLPCQIHPSPLKRSMSLIP 241 G P PS + PA+ GS+ A TG ++ P PLK++ + Sbjct: 1287 GEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVD 1346 Query: 242 TSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSGM 301 +V E E F + P S+A+S R + S Sbjct: 1347 N--RVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAP 1404 Query: 302 KDVPSWLKSLRLHKYAALF-----SQMSYEEMMTLTEQHLESQNVTKGARH-KIALSIQK 355 +D S + +R + S ++ T E+++V + K+ S + Sbjct: 1405 EDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLR 1464 Query: 356 --LRERQSVLKSLEKD--VLEGGNLRNALQE-----LQQIIITPIKAYSVLQATVAAATT 406 L +R++++ L +D A Q + +K V Q + AAT Sbjct: 1465 RTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATP 1524 Query: 407 T--------------PTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPA 452 T PT AP P P P P +D GT PP PPPP Sbjct: 1525 TEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPP----LPPPPE 1580 Query: 453 PAP-TDGSEPAPAP 465 P G E AP P Sbjct: 1581 SGPGQPGWEGAPQP 1594 Score = 30.8 bits (68), Expect = 4.4 Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 24/89 (26%) Query: 405 TTTPTAKDGAPGEPP----------------LPGAEPPLAHPGTDKGTEAKDPPAVENYP 448 T TPTA+ P PP P + PG +G E + P P Sbjct: 1238 TWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPG--QGLENRGEPPT---P 1292 Query: 449 PPPAPAPT---DGSEPAPAPVADGDIPSQ 474 P PAPAP GS + + A GD P + Sbjct: 1293 PSPAPAPAVAPGGSSESSSGRAAGDTPER 1321 >gi|24497513 homeobox A3 isoform a [Homo sapiens] Length = 443 Score = 40.8 bits (94), Expect = 0.004 Identities = 73/296 (24%), Positives = 113/296 (38%), Gaps = 57/296 (19%) Query: 392 KAYSVLQA---TVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYP 448 KA+ + +A T++A + P + P PP P A PP P A PPA Sbjct: 63 KAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQP----PQPAPQPPAPTPAA 118 Query: 449 PPP----APAPTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIE 504 PPP +P + P PA A + + T V ++ + SR + + TS E Sbjct: 119 PPPPSSASPPQNASNNPTPANAAKSPLLNSPT-VAKQIFPWMKESRQNTKQKTSSSSSGE 177 Query: 505 KCLTHEA---FTETQKKRLLSWKQQVLKLLRTFP------RKAALEMQNY-----RQQKG 550 C ++ +++ R Q+++L + F R +EM N RQ K Sbjct: 178 SCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 237 Query: 551 WAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSL 610 W F + + ++ Q+ G+L+ S GG SP + P Sbjct: 238 W-FQNRRMKY---------KKDQK------------GKGMLTSS--GGQSPSRSPVPPGA 273 Query: 611 GG--QGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCPVPGP 664 GG +L + P S P S+ Q T+ LP S P ++ P C P P Sbjct: 274 GGYLNSMHSLVNSVPYEPQSPPPFSKPP-QGTYGLPPASYPASL----PSCAPPPP 324 >gi|13562112 homeobox A3 isoform a [Homo sapiens] Length = 443 Score = 40.8 bits (94), Expect = 0.004 Identities = 73/296 (24%), Positives = 113/296 (38%), Gaps = 57/296 (19%) Query: 392 KAYSVLQA---TVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYP 448 KA+ + +A T++A + P + P PP P A PP P A PPA Sbjct: 63 KAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQP----PQPAPQPPAPTPAA 118 Query: 449 PPP----APAPTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENITSYLQLIE 504 PPP +P + P PA A + + T V ++ + SR + + TS E Sbjct: 119 PPPPSSASPPQNASNNPTPANAAKSPLLNSPT-VAKQIFPWMKESRQNTKQKTSSSSSGE 177 Query: 505 KCLTHEA---FTETQKKRLLSWKQQVLKLLRTFP------RKAALEMQNY-----RQQKG 550 C ++ +++ R Q+++L + F R +EM N RQ K Sbjct: 178 SCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 237 Query: 551 WAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSL 610 W F + + ++ Q+ G+L+ S GG SP + P Sbjct: 238 W-FQNRRMKY---------KKDQK------------GKGMLTSS--GGQSPSRSPVPPGA 273 Query: 611 GG--QGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCPVPGP 664 GG +L + P S P S+ Q T+ LP S P ++ P C P P Sbjct: 274 GGYLNSMHSLVNSVPYEPQSPPPFSKPP-QGTYGLPPASYPASL----PSCAPPPP 324 >gi|56682953 epidermal growth factor receptor pathway substrate 8 [Homo sapiens] Length = 822 Score = 40.8 bits (94), Expect = 0.004 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 4/67 (5%) Query: 415 PGEPPLPGAEPPLAHP----GTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGD 470 P E L A+PP H + G D P + PP PAP P PAPV Sbjct: 590 PPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSK 649 Query: 471 IPSQFTR 477 +P+ TR Sbjct: 650 VPANITR 656 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 40.4 bits (93), Expect = 0.006 Identities = 38/153 (24%), Positives = 56/153 (36%), Gaps = 20/153 (13%) Query: 322 QMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQ 381 Q+ ++M + EQ L+ K A H E+Q + + E L + Sbjct: 490 QVEMKKMESDFEQKLQDLQGEKDALHS---------EKQQIATEKQDLEAEVSQLTGEVA 540 Query: 382 ELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDP 441 +L + + K + L A + ++ P PPLPG D GT P Sbjct: 541 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPG----------DSGTIIPPP 590 Query: 442 PAV-ENYPPPPAPAPTDGSEPAPAPVADGDIPS 473 PA ++ PPP P P P P V PS Sbjct: 591 PAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPS 623 Score = 38.1 bits (87), Expect = 0.028 Identities = 22/68 (32%), Positives = 28/68 (41%), Gaps = 2/68 (2%) Query: 404 ATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYP--PPPAPAPTDGSEP 461 +TT P P PPLPG + P GT PP + PPP P P P Sbjct: 596 STTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP 655 Query: 462 APAPVADG 469 +P+ + G Sbjct: 656 SPSSLPGG 663 Score = 37.0 bits (84), Expect = 0.062 Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 10/81 (12%) Query: 397 LQATVAAATTTPTAKDGA-PGEPPLP---GAEPPLAHPGTDKGTEAKDPPAVEN---YPP 449 L A + P + D P PPLP G P + PG GT PP + PP Sbjct: 624 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG---GTAIPPPPPLPGSARIPP 680 Query: 450 PPAPAPTDGSEPAPAPVADGD 470 PP P P P P P G+ Sbjct: 681 PPPPLPGSAGIPPPPPPLPGE 701 Score = 35.4 bits (80), Expect = 0.18 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 4/61 (6%) Query: 413 GAPGEPPLPGAE---PPLAHPGTDKGTEAKDP-PAVENYPPPPAPAPTDGSEPAPAPVAD 468 G P LPG PP PG+ + P P PPPP P P + P P P Sbjct: 653 GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 712 Query: 469 G 469 G Sbjct: 713 G 713 Score = 35.4 bits (80), Expect = 0.18 Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 5/60 (8%) Query: 415 PGEPPLPGAE----PPLAHPGTDKGTEAKDP-PAVENYPPPPAPAPTDGSEPAPAPVADG 469 P PPLPG+ PP PG+ P P PPPP P P P P P G Sbjct: 667 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG 726 Score = 30.8 bits (68), Expect = 4.4 Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 2/53 (3%) Query: 415 PGEPPLPGAE--PPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAP 465 P PPLPG+ PP P + PP + P P P P G P P Sbjct: 680 PPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP 732 Score = 30.4 bits (67), Expect = 5.8 Identities = 34/139 (24%), Positives = 51/139 (36%), Gaps = 21/139 (15%) Query: 415 PGEPPLPGAE---PPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDI 471 P PPLPG PP PG G PP PPPP P PA + G Sbjct: 706 PPPPPLPGGPGIPPPPPFPG---GPGIPPPPPGMGMPPPP---PFGFGVPAAPVLPFGLT 759 Query: 472 PSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLL 531 P + + ++ + RP ++ +L+ + L+ + F K+ + KL Sbjct: 760 PKKLYK------PEVQLRRP------NWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLT 807 Query: 532 RTFPRKAALEMQNYRQQKG 550 TF + Q+ G Sbjct: 808 LTFSAQTKTSKAKKDQEGG 826 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 40.4 bits (93), Expect = 0.006 Identities = 38/153 (24%), Positives = 56/153 (36%), Gaps = 20/153 (13%) Query: 322 QMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQ 381 Q+ ++M + EQ L+ K A H E+Q + + E L + Sbjct: 499 QVEMKKMESDFEQKLQDLQGEKDALHS---------EKQQIATEKQDLEAEVSQLTGEVA 549 Query: 382 ELQQIIITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDP 441 +L + + K + L A + ++ P PPLPG D GT P Sbjct: 550 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPG----------DSGTIIPPP 599 Query: 442 PAV-ENYPPPPAPAPTDGSEPAPAPVADGDIPS 473 PA ++ PPP P P P P V PS Sbjct: 600 PAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPS 632 Score = 38.1 bits (87), Expect = 0.028 Identities = 22/68 (32%), Positives = 28/68 (41%), Gaps = 2/68 (2%) Query: 404 ATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYP--PPPAPAPTDGSEP 461 +TT P P PPLPG + P GT PP + PPP P P P Sbjct: 605 STTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP 664 Query: 462 APAPVADG 469 +P+ + G Sbjct: 665 SPSSLPGG 672 Score = 37.0 bits (84), Expect = 0.062 Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 10/81 (12%) Query: 397 LQATVAAATTTPTAKDGA-PGEPPLP---GAEPPLAHPGTDKGTEAKDPPAVEN---YPP 449 L A + P + D P PPLP G P + PG GT PP + PP Sbjct: 633 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG---GTAIPPPPPLPGSARIPP 689 Query: 450 PPAPAPTDGSEPAPAPVADGD 470 PP P P P P P G+ Sbjct: 690 PPPPLPGSAGIPPPPPPLPGE 710 Score = 35.4 bits (80), Expect = 0.18 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 4/61 (6%) Query: 413 GAPGEPPLPGAE---PPLAHPGTDKGTEAKDP-PAVENYPPPPAPAPTDGSEPAPAPVAD 468 G P LPG PP PG+ + P P PPPP P P + P P P Sbjct: 662 GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 721 Query: 469 G 469 G Sbjct: 722 G 722 Score = 35.4 bits (80), Expect = 0.18 Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 5/60 (8%) Query: 415 PGEPPLPGAE----PPLAHPGTDKGTEAKDP-PAVENYPPPPAPAPTDGSEPAPAPVADG 469 P PPLPG+ PP PG+ P P PPPP P P P P P G Sbjct: 676 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG 735 Score = 30.8 bits (68), Expect = 4.4 Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 2/53 (3%) Query: 415 PGEPPLPGAE--PPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAP 465 P PPLPG+ PP P + PP + P P P P G P P Sbjct: 689 PPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP 741 Score = 30.4 bits (67), Expect = 5.8 Identities = 34/139 (24%), Positives = 51/139 (36%), Gaps = 21/139 (15%) Query: 415 PGEPPLPGAE---PPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDI 471 P PPLPG PP PG G PP PPPP P PA + G Sbjct: 715 PPPPPLPGGPGIPPPPPFPG---GPGIPPPPPGMGMPPPP---PFGFGVPAAPVLPFGLT 768 Query: 472 PSQFTRVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLL 531 P + + ++ + RP ++ +L+ + L+ + F K+ + KL Sbjct: 769 PKKLYK------PEVQLRRP------NWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLT 816 Query: 532 RTFPRKAALEMQNYRQQKG 550 TF + Q+ G Sbjct: 817 LTFSAQTKTSKAKKDQEGG 835 >gi|148536848 carboxyl ester lipase precursor [Homo sapiens] Length = 756 Score = 40.4 bits (93), Expect = 0.006 Identities = 30/97 (30%), Positives = 32/97 (32%), Gaps = 21/97 (21%) Query: 403 AATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPP------------- 449 A PT GAP PP A PP P D G P PP Sbjct: 659 APPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVP 718 Query: 450 -------PPAPAPTDGSEPAPAPVADGDIPSQFTRVM 479 PP P PT SE AP P D +Q V+ Sbjct: 719 PTGDSGAPPVP-PTGDSEAAPVPPTDDSKEAQMPAVI 754 Score = 39.3 bits (90), Expect = 0.012 Identities = 24/70 (34%), Positives = 27/70 (38%), Gaps = 2/70 (2%) Query: 403 AATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPA 462 A PT GAP PP + P P D G PP + PPP P G+ P Sbjct: 637 APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV-PPTGDAGPPPVPPTGDSGAPPV 695 Query: 463 PAPVADGDIP 472 P P D P Sbjct: 696 P-PTGDSGAP 704 Score = 38.5 bits (88), Expect = 0.021 Identities = 37/130 (28%), Positives = 47/130 (36%), Gaps = 10/130 (7%) Query: 351 LSIQKLRERQSVLKSLEKDVLEGGNLRN-ALQELQQIIITPIKAYSVLQATVAAAT---- 405 L I K S+ +SL + L L AL + TP+ +AT T Sbjct: 522 LEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSE 581 Query: 406 ---TTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPA 462 PT GAP PP + P P D G PP ++ PP P G+ P Sbjct: 582 TAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV-PPTGDSGAPPVPPTGDSGAPPV 640 Query: 463 PAPVADGDIP 472 P P D P Sbjct: 641 P-PTGDSGAP 649 Score = 37.4 bits (85), Expect = 0.047 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 2/70 (2%) Query: 403 AATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPA 462 A PT GAP PP + P P D G PP ++ PP P G+ P Sbjct: 593 APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV-PPTGDSGAPPVPPTGDSGAPPV 651 Query: 463 PAPVADGDIP 472 P P D P Sbjct: 652 P-PTGDSGAP 660 Score = 37.4 bits (85), Expect = 0.047 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 2/70 (2%) Query: 403 AATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPA 462 A PT GAP PP + P P D G PP ++ PP P G+ P Sbjct: 604 APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV-PPTGDSGAPPVPPTGDSGAPPV 662 Query: 463 PAPVADGDIP 472 P P D P Sbjct: 663 P-PTGDSGAP 671 Score = 36.6 bits (83), Expect = 0.080 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 2/70 (2%) Query: 403 AATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPA 462 A PT GAP PP + P P D G PP ++ PP P G+ P Sbjct: 615 APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV-PPTGDSGAPPVPPTGDSGAPPV 673 Query: 463 PAPVADGDIP 472 P P D P Sbjct: 674 P-PTGDAGPP 682 Score = 33.9 bits (76), Expect = 0.52 Identities = 24/72 (33%), Positives = 27/72 (37%), Gaps = 10/72 (13%) Query: 403 AATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPP---------PAP 453 A PT GAP PP + P P D G PP ++ PP P Sbjct: 648 APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPV-PPTGDSGAPPVPPTGDSGAPPV 706 Query: 454 APTDGSEPAPAP 465 PT SE AP P Sbjct: 707 TPTGDSETAPVP 718 >gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens] Length = 768 Score = 40.4 bits (93), Expect = 0.006 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 13/90 (14%) Query: 389 TPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPP-----LAHPGTDKGTEAKDPPA 443 TPIK L+ + TT D A +P LP P L P +K EA PP+ Sbjct: 645 TPIK----LEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPS 700 Query: 444 VENYPPPPAPAPTDGSEPAPAPVADGDIPS 473 P +P P P PAPVA+ PS Sbjct: 701 PTEAPTEASPEPA----PDPAPVAEEAAPS 726 Score = 30.0 bits (66), Expect = 7.5 Identities = 27/75 (36%), Positives = 32/75 (42%), Gaps = 16/75 (21%) Query: 403 AATTTPTAKDGAPGEP------PLPGAEPPLAHPG--TDKGTEAKDPPAVENYPPPPAPA 454 AAT PT D +P EP P+ E P T+ TEA PA P PAP Sbjct: 665 AATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPA-----PDPAPV 719 Query: 455 PTDGSEPAPAPVADG 469 E AP+ V +G Sbjct: 720 ---AEEAAPSAVEEG 731 >gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens] Length = 737 Score = 40.4 bits (93), Expect = 0.006 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 13/90 (14%) Query: 389 TPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPP-----LAHPGTDKGTEAKDPPA 443 TPIK L+ + TT D A +P LP P L P +K EA PP+ Sbjct: 614 TPIK----LEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPS 669 Query: 444 VENYPPPPAPAPTDGSEPAPAPVADGDIPS 473 P +P P P PAPVA+ PS Sbjct: 670 PTEAPTEASPEPA----PDPAPVAEEAAPS 695 Score = 30.0 bits (66), Expect = 7.5 Identities = 27/75 (36%), Positives = 32/75 (42%), Gaps = 16/75 (21%) Query: 403 AATTTPTAKDGAPGEP------PLPGAEPPLAHPG--TDKGTEAKDPPAVENYPPPPAPA 454 AAT PT D +P EP P+ E P T+ TEA PA P PAP Sbjct: 634 AATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPA-----PDPAPV 688 Query: 455 PTDGSEPAPAPVADG 469 E AP+ V +G Sbjct: 689 ---AEEAAPSAVEEG 700 >gi|4507691 transformation/transcription domain-associated protein [Homo sapiens] Length = 3830 Score = 40.4 bits (93), Expect = 0.006 Identities = 28/103 (27%), Positives = 37/103 (35%), Gaps = 15/103 (14%) Query: 368 KDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTTPTAKDGA-----PGEPPLPG 422 K E GN R+ L + ++ + + Q + P ++ GA PG P P Sbjct: 433 KSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAVEAALPGVPTAPA 492 Query: 423 AEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAP 465 A P P P PPPP P P PAP P Sbjct: 493 APGPAPSPA----------PVPAPPPPPPPPPPATPVTPAPVP 525 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 40.4 bits (93), Expect = 0.006 Identities = 49/220 (22%), Positives = 77/220 (35%), Gaps = 16/220 (7%) Query: 255 ELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLH 314 E + A T A L+ SS + EE +++ E G + + S + Sbjct: 589 EANSEEAITPQQSAELASMELNESSRWTE-EEMETAKKGLLEHGRNWSAIARMVGSKTVS 647 Query: 315 KYAAL-FSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEG 373 + F+ + + + +QH + AR K + E + +E + +E Sbjct: 648 QCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEA 707 Query: 374 ----GNLRNALQELQQIIITPIKAYSVLQATVAAATTT------PTAKDGAPGEPPLPGA 423 GN ++E + + S+ AA T P A GA G PP P Sbjct: 708 SGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPT 767 Query: 424 EPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAP 463 PP P + T A + P P PAP S P P Sbjct: 768 PPPEDIPAPTEPTPASEATGA----PTPPPAPPSPSAPPP 803 Score = 32.7 bits (73), Expect = 1.2 Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 13/101 (12%) Query: 373 GGNLRNALQELQQIIITPIKAYSVLQATVAAATT------TPTAKDGA-PGEPPLPGAEP 425 GG L L + ++ P +A V + A T P A+ G P P G+EP Sbjct: 1913 GGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEP 1972 Query: 426 -----PLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEP 461 P++ T T AK+ P PPAP P S+P Sbjct: 1973 RPLVPPVSGHATIARTPAKNLAPHHASPDPPAP-PASASDP 2012 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.130 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,831,157 Number of Sequences: 37866 Number of extensions: 2000453 Number of successful extensions: 18798 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 207 Number of HSP's successfully gapped in prelim test: 780 Number of HSP's that attempted gapping in prelim test: 11412 Number of HSP's gapped (non-prelim): 6554 length of query: 694 length of database: 18,247,518 effective HSP length: 109 effective length of query: 585 effective length of database: 14,120,124 effective search space: 8260272540 effective search space used: 8260272540 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.