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Search of human proteins with 52426789
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo
sapiens]
(337 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo ... 686 0.0
gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 221 7e-58
gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 201 8e-52
gi|47271392 succinate receptor 1 [Homo sapiens] 185 4e-47
gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 184 1e-46
gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 184 1e-46
gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 184 1e-46
gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 183 2e-46
gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens] 157 2e-38
gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens] 157 2e-38
gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens] 157 2e-38
gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens] 157 2e-38
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 153 2e-37
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 153 2e-37
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 153 2e-37
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 153 2e-37
gi|14043044 chemokine (C-C motif) receptor 9 isoform B [Homo sap... 150 2e-36
gi|14043042 chemokine (C-C motif) receptor 9 isoform A [Homo sap... 150 2e-36
gi|166362740 coagulation factor II receptor precursor [Homo sapi... 147 1e-35
gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 144 9e-35
gi|30581170 CC chemokine receptor 3 [Homo sapiens] 144 1e-34
gi|4502637 CC chemokine receptor 3 [Homo sapiens] 144 1e-34
gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo sap... 144 1e-34
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 141 7e-34
gi|4885335 G protein-coupled receptor 4 [Homo sapiens] 135 7e-32
gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo sa... 134 1e-31
gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo s... 134 1e-31
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 133 2e-31
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 133 2e-31
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 133 2e-31
>gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo
sapiens]
Length = 337
Score = 686 bits (1771), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MNEPLDYLANASDFPDYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIF 60
MNEPLDYLANASDFPDYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIF
Sbjct: 1 MNEPLDYLANASDFPDYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIF 60
Query: 61 KMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSS 120
KMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSS
Sbjct: 61 KMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSS 120
Query: 121 ILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNR 180
ILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNR
Sbjct: 121 ILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNR 180
Query: 181 SACLDLTSSDELNTIKWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKAR 240
SACLDLTSSDELNTIKWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKAR
Sbjct: 181 SACLDLTSSDELNTIKWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKAR 240
Query: 241 RLTILLLLAFYVCFLPFHILRVIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLL 300
RLTILLLLAFYVCFLPFHILRVIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLL
Sbjct: 241 RLTILLLLAFYVCFLPFHILRVIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLL 300
Query: 301 LYVVVSDNFQQAVCSTVRCKVSGNLEQAKKISYSNNP 337
LYVVVSDNFQQAVCSTVRCKVSGNLEQAKKISYSNNP
Sbjct: 301 LYVVVSDNFQQAVCSTVRCKVSGNLEQAKKISYSNNP 337
>gi|4505557 purinergic receptor P2Y1 [Homo sapiens]
Length = 373
Score = 221 bits (563), Expect = 7e-58
Identities = 108/299 (36%), Positives = 176/299 (58%), Gaps = 4/299 (1%)
Query: 24 CTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYL 83
C + +YLP +Y ++F++GF GN+V I ++F M+PW ++ M NLA D LY+
Sbjct: 42 CALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYV 101
Query: 84 TSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFS 143
+LP LI YY + +WIFGD MCK RF FH NLY SILFLTC S RY +++P+
Sbjct: 102 LTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLG 161
Query: 144 IHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRS-ACLDLTSSDELNTIKWYNLIL 202
K + A+ +VW+I +VA+ P+ F + R N++ C D TS + L + Y++
Sbjct: 162 RLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCT 221
Query: 203 TATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRV 262
T FC+PLV++ CY I+ L + +S L++K+ L I++L F V ++PFH+++
Sbjct: 222 TVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKT 281
Query: 263 IRIESRL---LSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVR 318
+ + +RL C+ ++++ Y V+R LA+LN+ + +LY + D F++ + R
Sbjct: 282 MNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATR 340
>gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]
Length = 365
Score = 201 bits (511), Expect = 8e-52
Identities = 99/282 (35%), Positives = 162/282 (57%), Gaps = 2/282 (0%)
Query: 32 KMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIH 91
K LPV Y ++F++G NA + +IF++RPW ++ M +LA +D LY+ SLP LI+
Sbjct: 34 KFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIY 93
Query: 92 YYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAV 151
YYA+ +W FG +CKF+RF F++NLY S+LFLTC S+ RY I HP+ + R A
Sbjct: 94 YYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAG 153
Query: 152 VACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPL 211
+ C VW++ ++P F +T++N+ C D T +E + ++ + F +P
Sbjct: 154 LLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPC 213
Query: 212 VIVTLCYTTIIHTLTHGL--QTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRL 269
++ +CY + L L S + ++ R ++L F VCF+PFHI R I +RL
Sbjct: 214 LVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARL 273
Query: 270 LSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQ 311
L C + N ++ Y V+RPLA+ N+ + +LY++ D +++
Sbjct: 274 LEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRR 315
>gi|47271392 succinate receptor 1 [Homo sapiens]
Length = 334
Score = 185 bits (470), Expect = 4e-47
Identities = 107/293 (36%), Positives = 167/293 (56%), Gaps = 7/293 (2%)
Query: 31 LKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLI 90
L+ +YL + YGI F+VG GN +V+ YIF ++ W SS I + NL+ +DL +L +LP LI
Sbjct: 21 LEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLI 80
Query: 91 HYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCA 150
YA+G NWI+GD +C R+ H NLY+SILFLT SI RY +I +P + K A
Sbjct: 81 RSYANG-NWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFA 139
Query: 151 VVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLP 210
++ +W++ + ++P+ LI N + C D SS + N Y++ LT F +P
Sbjct: 140 ILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIP 199
Query: 211 LVIVTLCYTTI-IHTLTHGLQTDSCLK-QKARRLTILLLLAFYVCFLPFHILRVIRIESR 268
L ++ Y I + Q + L +K L I+ ++ F V F P+H++R +RI SR
Sbjct: 200 LFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASR 259
Query: 269 LLS---ISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVR 318
L S C+ + I+ YIV+RPLA LN+ N + Y ++ D+F+ + + +R
Sbjct: 260 LGSWKQYQCT-QVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLR 311
>gi|28872720 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 184 bits (466), Expect = 1e-46
Identities = 94/279 (33%), Positives = 151/279 (54%), Gaps = 4/279 (1%)
Query: 28 NIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLP 87
N K LPV YG++ + G NAV + ++ +++ W +ST M +LA +D LY SLP
Sbjct: 28 NEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLP 87
Query: 88 FLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKT 147
L++YYA G++W F +CK +RF F+ NLY SILFLTC S+ R ++ P+ +
Sbjct: 88 LLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRA 147
Query: 148 RCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTF 207
R A VW++ L P+ + +T++ R R C D ++ + + Y+ ++ F
Sbjct: 148 RYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLF 207
Query: 208 CLPLVIVTLCYTTIIHTLTHGLQTDS----CLKQKARRLTILLLLAFYVCFLPFHILRVI 263
+P ++ +CY + L S K+K+ R ++L F +CFLPFH+ R +
Sbjct: 208 AVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTL 267
Query: 264 RIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLY 302
R L +SC N I+ AY V+RPLA+ N+ + +LY
Sbjct: 268 YYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306
>gi|28872745 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 184 bits (466), Expect = 1e-46
Identities = 94/279 (33%), Positives = 151/279 (54%), Gaps = 4/279 (1%)
Query: 28 NIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLP 87
N K LPV YG++ + G NAV + ++ +++ W +ST M +LA +D LY SLP
Sbjct: 28 NEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLP 87
Query: 88 FLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKT 147
L++YYA G++W F +CK +RF F+ NLY SILFLTC S+ R ++ P+ +
Sbjct: 88 LLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRA 147
Query: 148 RCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTF 207
R A VW++ L P+ + +T++ R R C D ++ + + Y+ ++ F
Sbjct: 148 RYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLF 207
Query: 208 CLPLVIVTLCYTTIIHTLTHGLQTDS----CLKQKARRLTILLLLAFYVCFLPFHILRVI 263
+P ++ +CY + L S K+K+ R ++L F +CFLPFH+ R +
Sbjct: 208 AVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTL 267
Query: 264 RIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLY 302
R L +SC N I+ AY V+RPLA+ N+ + +LY
Sbjct: 268 YYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306
>gi|28872743 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 184 bits (466), Expect = 1e-46
Identities = 94/279 (33%), Positives = 151/279 (54%), Gaps = 4/279 (1%)
Query: 28 NIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLP 87
N K LPV YG++ + G NAV + ++ +++ W +ST M +LA +D LY SLP
Sbjct: 28 NEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLP 87
Query: 88 FLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKT 147
L++YYA G++W F +CK +RF F+ NLY SILFLTC S+ R ++ P+ +
Sbjct: 88 LLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRA 147
Query: 148 RCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTF 207
R A VW++ L P+ + +T++ R R C D ++ + + Y+ ++ F
Sbjct: 148 RYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLF 207
Query: 208 CLPLVIVTLCYTTIIHTLTHGLQTDS----CLKQKARRLTILLLLAFYVCFLPFHILRVI 263
+P ++ +CY + L S K+K+ R ++L F +CFLPFH+ R +
Sbjct: 208 AVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTL 267
Query: 264 RIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLY 302
R L +SC N I+ AY V+RPLA+ N+ + +LY
Sbjct: 268 YYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306
>gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]
Length = 346
Score = 183 bits (465), Expect = 2e-46
Identities = 108/315 (34%), Positives = 178/315 (56%), Gaps = 23/315 (7%)
Query: 23 NCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSST---IIMLNLACTD 79
NCT EN K + P++Y IIF G GN +S Y+F ++P+K ST + MLNLA +D
Sbjct: 30 NCTIENF--KREFFPIVYLIIFFWGVLGNG--LSIYVF-LQPYKKSTSVNVFMLNLAISD 84
Query: 80 LLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPM 139
LL++++LPF YY G NWIFGD C+ + +S + N+YSSI FLT S+ R+ ++HP
Sbjct: 85 LLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPF 144
Query: 140 SCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRS--ACLDLTSSDELNTIKW 197
+ R A + C ++WI+ + + I L+ S + N S +CL+L + ++ ++
Sbjct: 145 RLLHVTSIRSAWILCGIIWILIMASSI---MLLDSGSEQNGSVTSCLEL-NLYKIAKLQT 200
Query: 198 YNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLK---QKARRLTILLLLAFYVCF 254
N I LP +++CY II L +S L+ +KA I+ L+ F++CF
Sbjct: 201 MNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFLCF 260
Query: 255 LPFHILRVIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVC 314
LP+H LR + + + + + ++++H+A +++ LAA N N LLY +NF+ +
Sbjct: 261 LPYHTLRTVHLTTWKVGL---CKDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLK 317
Query: 315 STVRCKVSGNLEQAK 329
S +R G+ ++AK
Sbjct: 318 SALR---KGHPQKAK 329
>gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 157 bits (396), Expect = 2e-38
Identities = 94/288 (32%), Positives = 138/288 (47%), Gaps = 10/288 (3%)
Query: 32 KMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIH 91
K LP +Y + G P N VI+ R + + LNLA DLLY SLP LI+
Sbjct: 25 KQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIY 84
Query: 92 YYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHK---TR 148
YA G++W FGDF C+ +RF F+ NL+ SILFLTC S RY I HP++ + HK R
Sbjct: 85 NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPW--HKRGGRR 142
Query: 149 CAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFC 208
A + C VW+ +P + + NR+ C DL+ Y + LT F
Sbjct: 143 AAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFL 202
Query: 209 LPLVIVTLCYTTIIHTLTHGLQTDSCLKQ----KARRLTILLLLAFYVCFLPFHILRVIR 264
LP + CY + L + Q KA R+ +++ AF + FLPFHI +
Sbjct: 203 LPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAY 262
Query: 265 IESRLL-SISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQ 311
+ R + C++ AY +RP A+ N+ + +L+ F++
Sbjct: 263 LAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRR 310
>gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 157 bits (396), Expect = 2e-38
Identities = 94/288 (32%), Positives = 138/288 (47%), Gaps = 10/288 (3%)
Query: 32 KMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIH 91
K LP +Y + G P N VI+ R + + LNLA DLLY SLP LI+
Sbjct: 25 KQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIY 84
Query: 92 YYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHK---TR 148
YA G++W FGDF C+ +RF F+ NL+ SILFLTC S RY I HP++ + HK R
Sbjct: 85 NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPW--HKRGGRR 142
Query: 149 CAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFC 208
A + C VW+ +P + + NR+ C DL+ Y + LT F
Sbjct: 143 AAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFL 202
Query: 209 LPLVIVTLCYTTIIHTLTHGLQTDSCLKQ----KARRLTILLLLAFYVCFLPFHILRVIR 264
LP + CY + L + Q KA R+ +++ AF + FLPFHI +
Sbjct: 203 LPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAY 262
Query: 265 IESRLL-SISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQ 311
+ R + C++ AY +RP A+ N+ + +L+ F++
Sbjct: 263 LAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRR 310
>gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 157 bits (396), Expect = 2e-38
Identities = 94/288 (32%), Positives = 138/288 (47%), Gaps = 10/288 (3%)
Query: 32 KMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIH 91
K LP +Y + G P N VI+ R + + LNLA DLLY SLP LI+
Sbjct: 25 KQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIY 84
Query: 92 YYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHK---TR 148
YA G++W FGDF C+ +RF F+ NL+ SILFLTC S RY I HP++ + HK R
Sbjct: 85 NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPW--HKRGGRR 142
Query: 149 CAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFC 208
A + C VW+ +P + + NR+ C DL+ Y + LT F
Sbjct: 143 AAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFL 202
Query: 209 LPLVIVTLCYTTIIHTLTHGLQTDSCLKQ----KARRLTILLLLAFYVCFLPFHILRVIR 264
LP + CY + L + Q KA R+ +++ AF + FLPFHI +
Sbjct: 203 LPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAY 262
Query: 265 IESRLL-SISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQ 311
+ R + C++ AY +RP A+ N+ + +L+ F++
Sbjct: 263 LAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRR 310
>gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 157 bits (396), Expect = 2e-38
Identities = 94/288 (32%), Positives = 138/288 (47%), Gaps = 10/288 (3%)
Query: 32 KMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIH 91
K LP +Y + G P N VI+ R + + LNLA DLLY SLP LI+
Sbjct: 25 KQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIY 84
Query: 92 YYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHK---TR 148
YA G++W FGDF C+ +RF F+ NL+ SILFLTC S RY I HP++ + HK R
Sbjct: 85 NYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPW--HKRGGRR 142
Query: 149 CAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFC 208
A + C VW+ +P + + NR+ C DL+ Y + LT F
Sbjct: 143 AAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFL 202
Query: 209 LPLVIVTLCYTTIIHTLTHGLQTDSCLKQ----KARRLTILLLLAFYVCFLPFHILRVIR 264
LP + CY + L + Q KA R+ +++ AF + FLPFHI +
Sbjct: 203 LPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAY 262
Query: 265 IESRLL-SISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQ 311
+ R + C++ AY +RP A+ N+ + +L+ F++
Sbjct: 263 LAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRR 310
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 153 bits (387), Expect = 2e-37
Identities = 84/301 (27%), Positives = 151/301 (50%), Gaps = 5/301 (1%)
Query: 16 DYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNL 75
+++ A + PL+ Y + F++ GN + + +I + + + +++L
Sbjct: 14 NFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHL 73
Query: 76 ACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVI 135
A DL + LP + Y+ SG +W FG+ C+ F F+ N+Y+SI FLTC S R+ I
Sbjct: 74 AVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAI 133
Query: 136 IHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTI 195
+HP+ + + A +ACA +W++ VA+ P+ + + CL L +
Sbjct: 134 VHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASH-- 191
Query: 196 KWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFL 255
+ L+ A F P + CY II +L GL+ + LK KA R+ ++L F VCF+
Sbjct: 192 --HALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFV 249
Query: 256 PFHILR-VIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVC 314
P+H+ R V + R SC+ + + A ++ L +LN + ++Y V++ F+ A+C
Sbjct: 250 PYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALC 309
Query: 315 S 315
+
Sbjct: 310 N 310
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 153 bits (387), Expect = 2e-37
Identities = 84/301 (27%), Positives = 151/301 (50%), Gaps = 5/301 (1%)
Query: 16 DYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNL 75
+++ A + PL+ Y + F++ GN + + +I + + + +++L
Sbjct: 14 NFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHL 73
Query: 76 ACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVI 135
A DL + LP + Y+ SG +W FG+ C+ F F+ N+Y+SI FLTC S R+ I
Sbjct: 74 AVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAI 133
Query: 136 IHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTI 195
+HP+ + + A +ACA +W++ VA+ P+ + + CL L +
Sbjct: 134 VHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASH-- 191
Query: 196 KWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFL 255
+ L+ A F P + CY II +L GL+ + LK KA R+ ++L F VCF+
Sbjct: 192 --HALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFV 249
Query: 256 PFHILR-VIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVC 314
P+H+ R V + R SC+ + + A ++ L +LN + ++Y V++ F+ A+C
Sbjct: 250 PYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALC 309
Query: 315 S 315
+
Sbjct: 310 N 310
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 153 bits (387), Expect = 2e-37
Identities = 84/301 (27%), Positives = 151/301 (50%), Gaps = 5/301 (1%)
Query: 16 DYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNL 75
+++ A + PL+ Y + F++ GN + + +I + + + +++L
Sbjct: 42 NFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHL 101
Query: 76 ACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVI 135
A DL + LP + Y+ SG +W FG+ C+ F F+ N+Y+SI FLTC S R+ I
Sbjct: 102 AVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAI 161
Query: 136 IHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTI 195
+HP+ + + A +ACA +W++ VA+ P+ + + CL L +
Sbjct: 162 VHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASH-- 219
Query: 196 KWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFL 255
+ L+ A F P + CY II +L GL+ + LK KA R+ ++L F VCF+
Sbjct: 220 --HALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFV 277
Query: 256 PFHILR-VIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVC 314
P+H+ R V + R SC+ + + A ++ L +LN + ++Y V++ F+ A+C
Sbjct: 278 PYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALC 337
Query: 315 S 315
+
Sbjct: 338 N 338
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 153 bits (387), Expect = 2e-37
Identities = 84/301 (27%), Positives = 151/301 (50%), Gaps = 5/301 (1%)
Query: 16 DYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNL 75
+++ A + PL+ Y + F++ GN + + +I + + + +++L
Sbjct: 42 NFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHL 101
Query: 76 ACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVI 135
A DL + LP + Y+ SG +W FG+ C+ F F+ N+Y+SI FLTC S R+ I
Sbjct: 102 AVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAI 161
Query: 136 IHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTI 195
+HP+ + + A +ACA +W++ VA+ P+ + + CL L +
Sbjct: 162 VHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASH-- 219
Query: 196 KWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFL 255
+ L+ A F P + CY II +L GL+ + LK KA R+ ++L F VCF+
Sbjct: 220 --HALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFV 277
Query: 256 PFHILR-VIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVC 314
P+H+ R V + R SC+ + + A ++ L +LN + ++Y V++ F+ A+C
Sbjct: 278 PYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALC 337
Query: 315 S 315
+
Sbjct: 338 N 338
>gi|14043044 chemokine (C-C motif) receptor 9 isoform B [Homo
sapiens]
Length = 357
Score = 150 bits (378), Expect = 2e-36
Identities = 98/317 (30%), Positives = 162/317 (51%), Gaps = 13/317 (4%)
Query: 24 CTDENI-PLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLY 82
C N+ H+LP +Y ++F+VG GN++VI Y + R + + +LNLA DLL+
Sbjct: 26 CEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLF 85
Query: 83 LTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCF 142
L +LPF A+ + W F FMCK + + N YS +L + C S+ RY I M
Sbjct: 86 LVTLPFWA--IAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAH 143
Query: 143 SIHKTRC--AVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNL 200
+ + R + + C +W+++ IP + + C + SDE +K L
Sbjct: 144 TWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTMVYPSDESTKLKSAVL 203
Query: 201 ILTATT-FCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFH- 258
L F LP V++ CYT IIHTL +Q K KA ++TI +L F + P++
Sbjct: 204 TLKVILGFFLPFVVMACCYTIIIHTL---IQAKKSSKHKALKVTITVLTVFVLSQFPYNC 260
Query: 259 ILRVIRIESRLLSIS-CSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTV 317
IL V I++ + IS C++ I + V++ +A ++ N +LYV V + F++ + T+
Sbjct: 261 ILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTL 320
Query: 318 RCKVSGNLEQAKKISYS 334
K G + QA+ +S++
Sbjct: 321 --KNLGCISQAQWVSFT 335
>gi|14043042 chemokine (C-C motif) receptor 9 isoform A [Homo
sapiens]
Length = 369
Score = 150 bits (378), Expect = 2e-36
Identities = 98/317 (30%), Positives = 162/317 (51%), Gaps = 13/317 (4%)
Query: 24 CTDENI-PLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLY 82
C N+ H+LP +Y ++F+VG GN++VI Y + R + + +LNLA DLL+
Sbjct: 38 CEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLF 97
Query: 83 LTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCF 142
L +LPF A+ + W F FMCK + + N YS +L + C S+ RY I M
Sbjct: 98 LVTLPFWA--IAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAH 155
Query: 143 SIHKTRC--AVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNL 200
+ + R + + C +W+++ IP + + C + SDE +K L
Sbjct: 156 TWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTMVYPSDESTKLKSAVL 215
Query: 201 ILTATT-FCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFH- 258
L F LP V++ CYT IIHTL +Q K KA ++TI +L F + P++
Sbjct: 216 TLKVILGFFLPFVVMACCYTIIIHTL---IQAKKSSKHKALKVTITVLTVFVLSQFPYNC 272
Query: 259 ILRVIRIESRLLSIS-CSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTV 317
IL V I++ + IS C++ I + V++ +A ++ N +LYV V + F++ + T+
Sbjct: 273 ILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTL 332
Query: 318 RCKVSGNLEQAKKISYS 334
K G + QA+ +S++
Sbjct: 333 --KNLGCISQAQWVSFT 347
>gi|166362740 coagulation factor II receptor precursor [Homo
sapiens]
Length = 425
Score = 147 bits (372), Expect = 1e-35
Identities = 88/296 (29%), Positives = 155/296 (52%), Gaps = 12/296 (4%)
Query: 35 YLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYA 94
++P +Y +F+V P N + I +I KM+ K + + ML+LA D+L+++ LPF I YY
Sbjct: 104 FVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYF 163
Query: 95 SGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVAC 154
SG +W FG +C+F+ +F+ N+Y+SIL +T SI R+ +++PM S A C
Sbjct: 164 SGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTC 223
Query: 155 AVVWIISLVAVIPM-----TFLITSTNRTNRSACLDLTSSDEL-NTIKWYNLILTATTFC 208
+W +++ V+P+ T + N T C D+ + L +Y +A F
Sbjct: 224 LAIWALAIAGVVPLLLKEQTIQVPGLNIT---TCHDVLNETLLEGYYAYYFSAFSAVFFF 280
Query: 209 LPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESR 268
+PL+I T+CY +II L+ + K +A L+ + F +CF P ++L +
Sbjct: 281 VPLIISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYS-- 338
Query: 269 LLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVRCKVSGN 324
LS + + E + AY++ +++++ + L+Y S Q+ V S + CK S +
Sbjct: 339 FLSHTSTTE-AAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSD 393
>gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]
Length = 361
Score = 144 bits (364), Expect = 9e-35
Identities = 79/309 (25%), Positives = 148/309 (47%), Gaps = 8/309 (2%)
Query: 36 LPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYAS 95
+P+ Y ++F++G GN + + + + S+T+ NL +D+L+ T+LP I YYA
Sbjct: 34 MPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAM 93
Query: 96 GENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACA 155
G +W GD +C+ F+ N Y+ + F+TC SI R+ ++HP+ I + A C
Sbjct: 94 GFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCI 153
Query: 156 VVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPLVIVT 215
VWI+ +P+ S R C++ + +E ++ W L + LPL+I+
Sbjct: 154 FVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIIL 213
Query: 216 LCYTTIIHTL-----THGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLL 270
+CY+ I L + L S + +KA IL+++ F +CF P+H+ + + +L
Sbjct: 214 ICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLR 273
Query: 271 ---SISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVRCKVSGNLEQ 327
+ CS + + + L N + +Y +++ V ++ +VS ++
Sbjct: 274 FSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISS 333
Query: 328 AKKISYSNN 336
A K + N
Sbjct: 334 AVKSAPEEN 342
>gi|30581170 CC chemokine receptor 3 [Homo sapiens]
Length = 355
Score = 144 bits (362), Expect = 1e-34
Identities = 86/284 (30%), Positives = 144/284 (50%), Gaps = 8/284 (2%)
Query: 31 LKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLI 90
L ++P +Y ++F VG GN VV+ I R + I +LNLA +DLL+L +LPF I
Sbjct: 32 LMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWI 91
Query: 91 HYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCA 150
HY G NW+FG MCK + +H LYS I F+ +I RY I+H +
Sbjct: 92 HY-VRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFG 150
Query: 151 VVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFC-- 208
V+ V W ++++A +P + + C L D + + + ++ L T FC
Sbjct: 151 VITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFH-TLRMTIFCLV 209
Query: 209 LPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHI-LRVIRIES 267
LPL+++ +CYT II TL L+ S K KA RL +++ F++ + P+++ + + +S
Sbjct: 210 LPLLVMAICYTGIIKTL---LRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQS 266
Query: 268 RLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQ 311
L C + +V+ +A + N ++Y V + F++
Sbjct: 267 ILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRK 310
>gi|4502637 CC chemokine receptor 3 [Homo sapiens]
Length = 355
Score = 144 bits (362), Expect = 1e-34
Identities = 86/284 (30%), Positives = 144/284 (50%), Gaps = 8/284 (2%)
Query: 31 LKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLI 90
L ++P +Y ++F VG GN VV+ I R + I +LNLA +DLL+L +LPF I
Sbjct: 32 LMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWI 91
Query: 91 HYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCA 150
HY G NW+FG MCK + +H LYS I F+ +I RY I+H +
Sbjct: 92 HY-VRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFG 150
Query: 151 VVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFC-- 208
V+ V W ++++A +P + + C L D + + + ++ L T FC
Sbjct: 151 VITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFH-TLRMTIFCLV 209
Query: 209 LPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHI-LRVIRIES 267
LPL+++ +CYT II TL L+ S K KA RL +++ F++ + P+++ + + +S
Sbjct: 210 LPLLVMAICYTGIIKTL---LRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQS 266
Query: 268 RLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQ 311
L C + +V+ +A + N ++Y V + F++
Sbjct: 267 ILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRK 310
>gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo
sapiens]
Length = 359
Score = 144 bits (362), Expect = 1e-34
Identities = 90/294 (30%), Positives = 146/294 (49%), Gaps = 17/294 (5%)
Query: 36 LPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYAS 95
LPV+Y ++ V PGN + +M P S I M+NL+ TDL+ + LPF I+Y+ +
Sbjct: 26 LPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCN 85
Query: 96 GENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACA 155
+W+FG +C + +F+ N+YSSIL +TC S+ R+ +++P+S + R AV ACA
Sbjct: 86 RHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACA 145
Query: 156 VVWIISLVAVIPM--TFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTA---TTFCLP 210
W++ L A+ P+ T L + C D+ L ++ + + L F +P
Sbjct: 146 GTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIP 205
Query: 211 LVIVTLCYTTIIHTLTHGLQTDSCLKQKARR----LTILLLLAFYVCFLPFHILRVIRIE 266
VI CYT I L L+T+ ++ RR L ++LLAF CF P + + + I
Sbjct: 206 FVITVACYTATILKL---LRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIV 262
Query: 267 SRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVRCK 320
SRL + Y ++ L+ LN + +Y S FQ + + C+
Sbjct: 263 SRLF-----YGKSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCR 311
>gi|34577052 coagulation factor II (thrombin) receptor-like 1
precursor [Homo sapiens]
Length = 397
Score = 141 bits (356), Expect = 7e-34
Identities = 88/302 (29%), Positives = 149/302 (49%), Gaps = 18/302 (5%)
Query: 35 YLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYA 94
+LP++Y I+F+VG P N + + ++F+ + + I M NLA DLL + P I Y+
Sbjct: 77 FLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHI 136
Query: 95 SGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVAC 154
G NWI+G+ +C + F+ N+Y SILF+TC S+ RY VI++PM S K A+
Sbjct: 137 HGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMG-HSRKKANIAIGIS 195
Query: 155 AVVWIISLVAVIPM-----TFLITSTNRTNRSACL--DLTSSDELNTIKWYNLILTATTF 207
+W++ L+ IP+ T I + N T L L D N Y L L F
Sbjct: 196 LAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFN----YFLSLAIGVF 251
Query: 208 CLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKAR--RLTILLLLAFYVCFLPFHILRVIRI 265
P + Y +I L ++ K++ R +L + +L + +CF P ++L V+
Sbjct: 252 LFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVV-- 309
Query: 266 ESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVRCKVSGNL 325
I ++ ++ YIV+ L+ LN+ + +Y VS +F+ + + C+ +
Sbjct: 310 --HYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTV 367
Query: 326 EQ 327
+Q
Sbjct: 368 KQ 369
>gi|4885335 G protein-coupled receptor 4 [Homo sapiens]
Length = 362
Score = 135 bits (339), Expect = 7e-32
Identities = 79/283 (27%), Positives = 132/283 (46%), Gaps = 4/283 (1%)
Query: 37 PVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASG 96
P +Y + VG P N + + +++ + ++NL+ DLLY+ +LP + Y+
Sbjct: 21 PSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHH 80
Query: 97 ENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAV 156
+NWI G CK F F+ N+Y SI FL C S+ RY + HP+ + + + AV +V
Sbjct: 81 DNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSV 140
Query: 157 VWIISLVA-VIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPLVIVT 215
VW L A P+ +R N + C + + + W NL F P ++
Sbjct: 141 VWATELGANSAPLFHDELFRDRYNHTFCFEKFPME--GWVAWMNLYRVFVGFLFPWALML 198
Query: 216 LCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRL-LSISC 274
L Y I+ + + T+ K K +RL + L+ VCF P+H+L + R L C
Sbjct: 199 LSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWDC 258
Query: 275 SIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTV 317
E ++ AY S +LN + +LY +V++ + V +
Sbjct: 259 GFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKAL 301
>gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo
sapiens]
Length = 352
Score = 134 bits (337), Expect = 1e-31
Identities = 94/318 (29%), Positives = 152/318 (47%), Gaps = 17/318 (5%)
Query: 26 DENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTS 85
+EN +LP IY IIFL G GN +VI ++ + + L+L+ DLL++ +
Sbjct: 31 EENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVIT 90
Query: 86 LPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIH 145
LPF + NW FG+F+CK + + NLYSS+L L S+ RY I+H +
Sbjct: 91 LPFWA--VDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPR 148
Query: 146 KTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTAT 205
K V VWI +L+ IP + +R C +D + + I+
Sbjct: 149 KLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVG- 207
Query: 206 TFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRI 265
LP +++ CY II L+H + K+KA + T++L+LAF+ C+LP++I I I
Sbjct: 208 -LILPGIVILSCYCIIISKLSH---SKGHQKRKALKTTVILILAFFACWLPYYI--GISI 261
Query: 266 ES----RLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNF----QQAVCSTV 317
+S ++ C EN +H+ ++ LA + N +LY + F Q A+ S
Sbjct: 262 DSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVS 321
Query: 318 RCKVSGNLEQAKKISYSN 335
R L + K+ +S+
Sbjct: 322 RGSSLKILSKGKRGGHSS 339
>gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo
sapiens]
Length = 356
Score = 134 bits (337), Expect = 1e-31
Identities = 94/318 (29%), Positives = 152/318 (47%), Gaps = 17/318 (5%)
Query: 26 DENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTS 85
+EN +LP IY IIFL G GN +VI ++ + + L+L+ DLL++ +
Sbjct: 35 EENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVIT 94
Query: 86 LPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIH 145
LPF + NW FG+F+CK + + NLYSS+L L S+ RY I+H +
Sbjct: 95 LPFWA--VDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPR 152
Query: 146 KTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTAT 205
K V VWI +L+ IP + +R C +D + + I+
Sbjct: 153 KLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVG- 211
Query: 206 TFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRI 265
LP +++ CY II L+H + K+KA + T++L+LAF+ C+LP++I I I
Sbjct: 212 -LILPGIVILSCYCIIISKLSH---SKGHQKRKALKTTVILILAFFACWLPYYI--GISI 265
Query: 266 ES----RLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNF----QQAVCSTV 317
+S ++ C EN +H+ ++ LA + N +LY + F Q A+ S
Sbjct: 266 DSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVS 325
Query: 318 RCKVSGNLEQAKKISYSN 335
R L + K+ +S+
Sbjct: 326 RGSSLKILSKGKRGGHSS 343
>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 133 bits (335), Expect = 2e-31
Identities = 77/281 (27%), Positives = 144/281 (51%), Gaps = 7/281 (2%)
Query: 39 IYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGEN 98
++ ++F++G N V I +I ++ +T M+NLA +DLL++ +LPF I Y+ + N
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTT-RN 81
Query: 99 WIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVW 158
W FGD +CK F+ N+Y SILFLTC S+ R+ I++P ++ R A + C VW
Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141
Query: 159 IISLVAVIPMTFLITSTNRTNRS--ACLDLTSSDELNT-IKWYNLILTATTFCLPLVIVT 215
+ + P F+ ++ ++ N + AC + T + + + F +PL++
Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201
Query: 216 LCYTTIIHTLTH--GLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLS-I 272
C + ++ TLT L K K ++ + L+ F CF+P++I ++ R + +
Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261
Query: 273 SCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAV 313
+CS+ + Y ++ +A N + ++Y SD Q ++
Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSI 302
>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 133 bits (335), Expect = 2e-31
Identities = 77/281 (27%), Positives = 144/281 (51%), Gaps = 7/281 (2%)
Query: 39 IYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGEN 98
++ ++F++G N V I +I ++ +T M+NLA +DLL++ +LPF I Y+ + N
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTT-RN 81
Query: 99 WIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVW 158
W FGD +CK F+ N+Y SILFLTC S+ R+ I++P ++ R A + C VW
Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141
Query: 159 IISLVAVIPMTFLITSTNRTNRS--ACLDLTSSDELNT-IKWYNLILTATTFCLPLVIVT 215
+ + P F+ ++ ++ N + AC + T + + + F +PL++
Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201
Query: 216 LCYTTIIHTLTH--GLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLS-I 272
C + ++ TLT L K K ++ + L+ F CF+P++I ++ R + +
Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261
Query: 273 SCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAV 313
+CS+ + Y ++ +A N + ++Y SD Q ++
Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSI 302
>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 133 bits (335), Expect = 2e-31
Identities = 77/281 (27%), Positives = 144/281 (51%), Gaps = 7/281 (2%)
Query: 39 IYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGEN 98
++ ++F++G N V I +I ++ +T M+NLA +DLL++ +LPF I Y+ + N
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTT-RN 81
Query: 99 WIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVW 158
W FGD +CK F+ N+Y SILFLTC S+ R+ I++P ++ R A + C VW
Sbjct: 82 WPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVW 141
Query: 159 IISLVAVIPMTFLITSTNRTNRS--ACLDLTSSDELNT-IKWYNLILTATTFCLPLVIVT 215
+ + P F+ ++ ++ N + AC + T + + + F +PL++
Sbjct: 142 LTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNV 201
Query: 216 LCYTTIIHTLTH--GLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLS-I 272
C + ++ TLT L K K ++ + L+ F CF+P++I ++ R + +
Sbjct: 202 TCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFV 261
Query: 273 SCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAV 313
+CS+ + Y ++ +A N + ++Y SD Q ++
Sbjct: 262 NCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSI 302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.141 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,700,280
Number of Sequences: 37866
Number of extensions: 468985
Number of successful extensions: 2321
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 1433
Number of HSP's gapped (non-prelim): 531
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.