Guide to the Human Genome
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Search of human proteins with 51944966

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo
sapiens]
         (1035 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]   2072   0.0  
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]            1338   0.0  
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]  1330   0.0  
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]  1326   0.0  
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...  1323   0.0  
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]  1320   0.0  
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...  1317   0.0  
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...  1246   0.0  
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...   373   e-103
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   373   e-103
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...   373   e-103
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   373   e-103
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...   373   e-103
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...   373   e-103
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...   373   e-103
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...   371   e-102
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...   371   e-102
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...   356   7e-98
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...   356   7e-98
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...   356   7e-98
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...   356   7e-98
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...   356   7e-98
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...   356   7e-98
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...   344   3e-94
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...   331   2e-90
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...   253   9e-67
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...   223   9e-58
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...   223   9e-58
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...   221   2e-57
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...   221   2e-57

>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score = 2072 bits (5368), Expect = 0.0
 Identities = 1035/1035 (100%), Positives = 1035/1035 (100%)

Query: 1    MGKAENYELYSVELGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVA 60
            MGKAENYELYSVELGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVA
Sbjct: 1    MGKAENYELYSVELGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVA 60

Query: 61   ELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAA 120
            ELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAA
Sbjct: 61   ELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAA 120

Query: 121  ICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQA 180
            ICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQA
Sbjct: 121  ICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQA 180

Query: 181  TVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSP 240
            TVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSP
Sbjct: 181  TVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSP 240

Query: 241  ECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIE 300
            ECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIE
Sbjct: 241  ECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIE 300

Query: 301  HFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAK 360
            HFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAK
Sbjct: 301  HFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAK 360

Query: 361  RLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQ 420
            RLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQ
Sbjct: 361  RLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQ 420

Query: 421  TFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMG 480
            TFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMG
Sbjct: 421  TFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMG 480

Query: 481  YRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELP 540
            YRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELP
Sbjct: 481  YRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELP 540

Query: 541  LDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLV 600
            LDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLV
Sbjct: 541  LDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLV 600

Query: 601  SMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLR 660
            SMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLR
Sbjct: 601  SMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLR 660

Query: 661  VPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLG 720
            VPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLG
Sbjct: 661  VPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLG 720

Query: 721  AIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIF 780
            AIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIF
Sbjct: 721  AIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIF 780

Query: 781  DNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAES 840
            DNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAES
Sbjct: 781  DNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAES 840

Query: 841  DIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQ 900
            DIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQ
Sbjct: 841  DIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQ 900

Query: 901  WEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGF 960
            WEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGF
Sbjct: 901  WEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGF 960

Query: 961  FRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLG 1020
            FRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLG
Sbjct: 961  FRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLG 1020

Query: 1021 VRCCPGSWWDQELYY 1035
            VRCCPGSWWDQELYY
Sbjct: 1021 VRCCPGSWWDQELYY 1035


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score = 1338 bits (3463), Expect = 0.0
 Identities = 656/1014 (64%), Positives = 801/1014 (78%), Gaps = 1/1014 (0%)

Query: 22   MAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAE 81
            M  K   K       GK +  L+++KKE+ + +H++SV E+ +KY T   +GL+ S A E
Sbjct: 1    MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE 60

Query: 82   LLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNL 141
            +L RDGPNAL PP  TPE+VKF RQL GG   L+W+ A +C +A+ IQA   D  + DNL
Sbjct: 61   ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNL 120

Query: 142  YLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDL 201
            YL I L AVV++TGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K Q+NA+++VVGDL
Sbjct: 121  YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL 180

Query: 202  VEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCL 261
            VE+KGGDRVPAD+RI++A GCKVDNSSLTGESEPQTRSP+CTH++PLETRNI FFST C+
Sbjct: 181  VEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV 240

Query: 262  EGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVA 321
            EGT +G+VV TGDRT++GRIA+LASG+E  KTPIAIEIEHF+ +I G+A+  G +FFI++
Sbjct: 241  EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS 300

Query: 322  MCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGST 381
            + +GYT+L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGST
Sbjct: 301  LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST 360

Query: 382  SVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNR 441
            S ICSDKTGTLTQNRMTV+H+WFDN IH ADTTEDQSG +FD+SS TW AL  +  LCNR
Sbjct: 361  STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR 420

Query: 442  AAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQL 501
            A FK GQD +PV KR V GDASE+ALLK  EL+ G+    R+R  KV EIPFNSTNK+QL
Sbjct: 421  AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL 480

Query: 502  SIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGE 561
            SIH  EDP D R+LLVMKGAPER+L+RCS+IL++G+E PLDE+ +EAFQ AYL LGGLGE
Sbjct: 481  SIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGE 540

Query: 562  RVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAG 621
            RVLGFC  YL E+ +P G+AFD + +NF +  LCF GL+SMIDPPRA VPDAV KCR+AG
Sbjct: 541  RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG 600

Query: 622  IRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQL 681
            I+VIMVTGDHPITAKAIA  VGIISEG+ETVEDIAARL +PV QVN +DA+ACVI+G  L
Sbjct: 601  IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL 660

Query: 682  KDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADI 741
            KD    ++ E L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDSPALKKADI
Sbjct: 661  KDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI 720

Query: 742  GVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPY 801
            GVAMGIAGSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT NIPE+TP+
Sbjct: 721  GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF 780

Query: 802  LIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLA 861
            L++I  ++PLPLG ITIL I+L TD+ P++SLAYE AESDIM  +PRNP+ D+LVNE L 
Sbjct: 781  LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI 840

Query: 862  AYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQ 921
            + +Y QIG IQ+  GF  YF  +A+ G+ P   VG+R  W+D  + DL+DSYGQ+WT+ Q
Sbjct: 841  SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ 900

Query: 922  RLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLC 981
            R   ++TC+T FF+SI V Q AD++I KTRR S FQQG  +NKIL+  +  +  +  FL 
Sbjct: 901  RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLS 959

Query: 982  YCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035
            YCPGM       P++  WW    PY  LIFVYDEIRKL +R  PG W ++E YY
Sbjct: 960  YCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score = 1330 bits (3441), Expect = 0.0
 Identities = 664/1033 (64%), Positives = 808/1033 (78%), Gaps = 5/1033 (0%)

Query: 8    ELYSVELGPGPGGDMAAKMSKKKKAGGGGG-----KRKEKLENMKKEMEINDHQLSVAEL 62
            E+YSVEL          K   K+K  G        K+K   E  +KE+ ++DH+LS  EL
Sbjct: 7    EIYSVELSGTKDIVKTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNREL 66

Query: 63   EQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAIC 122
            E+KY T    GLS++ AAELL RDGPN+L PP+ TPE VKF +Q+ GG   L+WV A +C
Sbjct: 67   EEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLC 126

Query: 123  LIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATV 182
             IA+ IQ S     + +N+YL   L  VV++TG F YYQE KSTNI++SF  ++PQQA V
Sbjct: 127  WIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALV 186

Query: 183  IRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPEC 242
            IRD +K  I ++QLVVGD+VE+KGGD++PADIR+L++QGC+VDNSSLTGESEPQ RS E 
Sbjct: 187  IRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEF 246

Query: 243  THESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHF 302
            THE+PLET+NI F+ST CLEGTV G+V+NTGDRTIIG IASLASGV NEKTPIAIEIEHF
Sbjct: 247  THENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHF 306

Query: 303  VDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRL 362
            V I+AG+A+  G  FFI+A+ + Y  L +++F + I+VA VPEGLLATVTV LSLTAKR+
Sbjct: 307  VHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRM 366

Query: 363  ASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTF 422
            A KNC+VKNLEAVETLGSTS+ICSDKTGTLTQNRMTV+HLWFDN I  ADT+ED S Q F
Sbjct: 367  AKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVF 426

Query: 423  DQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYR 482
            DQSS TW +L +++TLCNRA FK GQ+ VP+ K+ VIGDASETALLKFSE+ LG+ M  R
Sbjct: 427  DQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIR 486

Query: 483  DRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLD 542
             R  KV EIPFNSTNKFQLSIH ++DP   R L+VMKGAPER+LE+CS+I+I G+E PLD
Sbjct: 487  KRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLD 546

Query: 543  EQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSM 602
            +   + F TAY+ LGGLGERVLGFC LYL   ++P  Y+FD++AMNFP+S LCF GL+SM
Sbjct: 547  KSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSM 606

Query: 603  IDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVP 662
            IDPPR+TVPDAV KCR+AGI+VIMVTGDHPITAKAIA SVGIIS  SETVEDIA RL + 
Sbjct: 607  IDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIA 666

Query: 663  VDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAI 722
            V+QVN++DA+A V+ GM+LKDM   +L E L  + E+VFARTSPQQKL+IVE CQR  A+
Sbjct: 667  VEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAV 726

Query: 723  VAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDN 782
            VAVTGDGVNDSPALKKADIG+AMGIAGSDAAKNAADM+LLDDNFASIVTGVE+GRLIFDN
Sbjct: 727  VAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDN 786

Query: 783  LKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDI 842
            LKK+IAY+LTKNI EL P+LIYI V +PLP+G ITILFI+L TDI PS++LAYEKAESDI
Sbjct: 787  LKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDI 846

Query: 843  MHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWE 902
            M+ +PR+  +DRLVN+PLA YSY  IG +Q+   F  YFT  AQEG+ P   + LR +WE
Sbjct: 847  MNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWE 906

Query: 903  DHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFR 962
              ++ DL+DSYGQEWT  QR Y ++T YT FF+ I V QIAD++IRKTRR S FQQG FR
Sbjct: 907  KDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFR 966

Query: 963  NKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVR 1022
            NK++ + I  Q+ IG  L Y  G     +F  +R Q+W V +P+ ILI+VYDE+RKL +R
Sbjct: 967  NKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIR 1026

Query: 1023 CCPGSWWDQELYY 1035
              PGSWWD+ +YY
Sbjct: 1027 LYPGSWWDKNMYY 1039


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score = 1326 bits (3431), Expect = 0.0
 Identities = 644/1024 (62%), Positives = 814/1024 (79%), Gaps = 3/1024 (0%)

Query: 14   LGPGPGGDM--AAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSAT 71
            +G G G D    A +S++    G  GK+   ++ +KKE+ ++DH+LS+ EL +KY T  +
Sbjct: 1    MGKGVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLS 60

Query: 72   KGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQAS 131
            +GL+++ AAE+L RDGPNAL PP  TPE++KF RQL GG   L+W+ A +C +A++IQA+
Sbjct: 61   RGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAA 120

Query: 132  EGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQI 191
              +   +DNLYL + L AVV++TGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K  I
Sbjct: 121  TEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSI 180

Query: 192  NADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETR 251
            NA+++VVGDLVE+KGGDR+PAD+RI++A GCKVDNSSLTGESEPQTRSP+ T+E+PLETR
Sbjct: 181  NAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETR 240

Query: 252  NIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAI 311
            NIAFFST C+EGT +G+VV TGDRT++GRIA+LASG+E  +TPIA EIEHF+ II G+A+
Sbjct: 241  NIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAV 300

Query: 312  LFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKN 371
              G +FFI+++ + YT+L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKN
Sbjct: 301  FLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN 360

Query: 372  LEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRA 431
            LEAVETLGSTS ICSDKTGTLTQNRMTV+H+WFDN IH ADTTE+QSG +FD++S TW A
Sbjct: 361  LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLA 420

Query: 432  LCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEI 491
            L R+  LCNRA F++ Q+ +P+ KR V GDASE+ALLK  EL  G+    R+R+ K+ EI
Sbjct: 421  LSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEI 480

Query: 492  PFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQT 551
            PFNSTNK+QLSIH   +  +P+HLLVMKGAPER+L+RCSSIL+ G+E PLDE+ ++AFQ 
Sbjct: 481  PFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN 540

Query: 552  AYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVP 611
            AYL LGGLGERVLGFC L+L ++ +P G+ FD + +NFP   LCF GL+SMIDPPRA VP
Sbjct: 541  AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP 600

Query: 612  DAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDA 671
            DAV KCR+AGI+VIMVTGDHPITAKAIA  VGIISEG+ETVEDIAARL +PV QVN +DA
Sbjct: 601  DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDA 660

Query: 672  RACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVN 731
            +ACV++G  LKDM   +L + L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVN
Sbjct: 661  KACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN 720

Query: 732  DSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTL 791
            DSPALKKADIGVAMGIAGSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTL
Sbjct: 721  DSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL 780

Query: 792  TKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851
            T NIPE+TP+LI+I  ++PLPLG +TIL I+L TD+ P++SLAYE+AESDIM  +PRNPK
Sbjct: 781  TSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPK 840

Query: 852  RDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQD 911
             D+LVNE L + +Y QIG IQ+  GF  YF  +A+ G+ P+  +GLR  W+D  + D++D
Sbjct: 841  TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVED 900

Query: 912  SYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIV 971
            SYGQ+WT+ QR   ++TC+T FF+SI V Q AD++I KTRR S FQQG  +NKIL+  + 
Sbjct: 901  SYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQG-MKNKILIFGLF 959

Query: 972  FQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQ 1031
             +  +  FL YCPGM       P++  WW    PY +LIFVYDE+RKL +R  PG W ++
Sbjct: 960  EETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEK 1019

Query: 1032 ELYY 1035
            E YY
Sbjct: 1020 ETYY 1023


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
          Length = 1023

 Score = 1323 bits (3425), Expect = 0.0
 Identities = 640/1012 (63%), Positives = 809/1012 (79%), Gaps = 1/1012 (0%)

Query: 24   AKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELL 83
            A +S++    G  GK+   ++ +KKE+ ++DH+LS+ EL +KY T  ++GL+++ AAE+L
Sbjct: 13   AAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEIL 72

Query: 84   LRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYL 143
             RDGPNAL PP  TPE++KF RQL GG   L+W+ A +C +A++IQA+  +   +DNLYL
Sbjct: 73   ARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYL 132

Query: 144  AIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVE 203
             + L AVV++TGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K  INA+++VVGDLVE
Sbjct: 133  GVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVE 192

Query: 204  MKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEG 263
            +KGGDR+PAD+RI++A GCKVDNSSLTGESEPQTRSP+ T+E+PLETRNIAFFST C+EG
Sbjct: 193  VKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEG 252

Query: 264  TVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMC 323
            T +G+VV TGDRT++GRIA+LASG+E  +TPIA EIEHF+ II G+A+  G +FFI+++ 
Sbjct: 253  TARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLI 312

Query: 324  IGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSV 383
            + YT+L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGSTS 
Sbjct: 313  LEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTST 372

Query: 384  ICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAA 443
            ICSDKTGTLTQNRMTV+H+WFDN IH ADTTE+QSG +FD++S TW AL R+  LCNRA 
Sbjct: 373  ICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAV 432

Query: 444  FKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSI 503
            F++ Q+ +P+ KR V GDASE+ALLK  EL  G+    R+R+ K+ EIPFNSTNK+QLSI
Sbjct: 433  FQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSI 492

Query: 504  HTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERV 563
            H   +  +P+HLLVMKGAPER+L+RCSSIL+ G+E PLDE+ ++AFQ AYL LGGLGERV
Sbjct: 493  HKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERV 552

Query: 564  LGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIR 623
            LGFC L+L ++ +P G+ FD + +NFP   LCF GL+SMIDPPRA VPDAV KCR+AGI+
Sbjct: 553  LGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIK 612

Query: 624  VIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKD 683
            VIMVTGDHPITAKAIA  VGIISEG+ETVEDIAARL +PV QVN +DA+ACV++G  LKD
Sbjct: 613  VIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKD 672

Query: 684  MDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGV 743
            M   +L + L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDSPALKKADIGV
Sbjct: 673  MTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGV 732

Query: 744  AMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLI 803
            AMGIAGSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT NIPE+TP+LI
Sbjct: 733  AMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLI 792

Query: 804  YITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAY 863
            +I  ++PLPLG +TIL I+L TD+ P++SLAYE+AESDIM  +PRNPK D+LVNE L + 
Sbjct: 793  FIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISM 852

Query: 864  SYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRL 923
            +Y QIG IQ+  GF  YF  +A+ G+ P+  +GLR  W+D  + D++DSYGQ+WT+ QR 
Sbjct: 853  AYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRK 912

Query: 924  YQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYC 983
              ++TC+T FF+SI V Q AD++I KTRR S FQQG  +NKIL+  +  +  +  FL YC
Sbjct: 913  IVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYC 971

Query: 984  PGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035
            PGM       P++  WW    PY +LIFVYDE+RKL +R  PG W ++E YY
Sbjct: 972  PGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score = 1320 bits (3417), Expect = 0.0
 Identities = 640/1022 (62%), Positives = 809/1022 (79%), Gaps = 2/1022 (0%)

Query: 14   LGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKG 73
            +G G G + +   +  +  GG   +++++L+ +KKE+ ++DH+LS+ EL +KYQ   +KG
Sbjct: 1    MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG 60

Query: 74   LSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEG 133
            L+   A ++L RDGPNAL PP  TPE+VKF RQL GG   L+W+ A +C +A+ IQA+  
Sbjct: 61   LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120

Query: 134  DLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINA 193
            D  ++DNLYL + L AVV+VTGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K QINA
Sbjct: 121  DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180

Query: 194  DQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNI 253
            +++VVGDLVE+KGGDRVPAD+RI+++ GCKVDNSSLTGESEPQTRSPE THE+PLETRNI
Sbjct: 181  EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI 240

Query: 254  AFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILF 313
             FFST C+EGT +G+V+ TGDRT++GRIA+LASG+E  +TPIA+EIEHF+ +I G+A+  
Sbjct: 241  CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL 300

Query: 314  GATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLE 373
            G +FF++++ +GY++L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLE
Sbjct: 301  GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE 360

Query: 374  AVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALC 433
            AVETLGSTS ICSDKTGTLTQNRMTV+H+WFDN IH ADTTEDQSG TFD+ S TW AL 
Sbjct: 361  AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS 420

Query: 434  RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPF 493
            R+  LCNRA FK+GQ+ + V KR   GDASE+ALLK  EL+ G+    RDR PKV EIPF
Sbjct: 421  RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF 480

Query: 494  NSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAY 553
            NSTNK+QLSIH  ED     H+LVMKGAPER+L+RCS+IL++G+E+PLD++ ++AFQ AY
Sbjct: 481  NSTNKYQLSIHERED-SPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAY 539

Query: 554  LSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDA 613
            + LGGLGERVLGFCQL L    +P G+ FD + +NFP+  LCF GL+SMIDPPRA VPDA
Sbjct: 540  MELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDA 599

Query: 614  VLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARA 673
            V KCR+AGI+VIMVTGDHPITAKAIA  VGIISEG+ETVEDIAARL +P+ QVN ++A+A
Sbjct: 600  VGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKA 659

Query: 674  CVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDS 733
            CV++G  LKDM   +L E L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDS
Sbjct: 660  CVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDS 719

Query: 734  PALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTK 793
            PALKKADIG+AMGI+GSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT 
Sbjct: 720  PALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTS 779

Query: 794  NIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRD 853
            NIPE+TP+L++I  ++PLPLG +TIL I+L TD+ P++SLAYE AESDIM  +PRN + D
Sbjct: 780  NIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTD 839

Query: 854  RLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSY 913
            +LVNE L + +Y QIG IQ+  GF  YF  +A+ G+ P   +G+R  W+D  + DL+DSY
Sbjct: 840  KLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSY 899

Query: 914  GQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQ 973
            GQEWT+ QR   ++TC+T FF SI V Q AD++I KTRR S FQQG  +NKIL+  ++ +
Sbjct: 900  GQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLLEE 958

Query: 974  VCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQEL 1033
              +  FL YCPGM       P++  WW    PY +LIF+YDE+RKL +R  PG W ++E 
Sbjct: 959  TALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKET 1018

Query: 1034 YY 1035
            YY
Sbjct: 1019 YY 1020


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens]
          Length = 992

 Score = 1317 bits (3408), Expect = 0.0
 Identities = 635/993 (63%), Positives = 800/993 (80%), Gaps = 1/993 (0%)

Query: 43   LENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVK 102
            ++ +KKE+ ++DH+LS+ EL +KY T  ++GL+++ AAE+L RDGPNAL PP  TPE++K
Sbjct: 1    MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60

Query: 103  FARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQE 162
            F RQL GG   L+W+ A +C +A++IQA+  +   +DNLYL + L AVV++TGCF YYQE
Sbjct: 61   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120

Query: 163  FKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGC 222
             KS+ I+ SFKN+VPQQA VIR+G+K  INA+++VVGDLVE+KGGDR+PAD+RI++A GC
Sbjct: 121  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180

Query: 223  KVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIA 282
            KVDNSSLTGESEPQTRSP+ T+E+PLETRNIAFFST C+EGT +G+VV TGDRT++GRIA
Sbjct: 181  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240

Query: 283  SLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAY 342
            +LASG+E  +TPIA EIEHF+ II G+A+  G +FFI+++ + YT+L A++F + I+VA 
Sbjct: 241  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300

Query: 343  VPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHL 402
            VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGSTS ICSDKTGTLTQNRMTV+H+
Sbjct: 301  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360

Query: 403  WFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDA 462
            WFDN IH ADTTE+QSG +FD++S TW AL R+  LCNRA F++ Q+ +P+ KR V GDA
Sbjct: 361  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420

Query: 463  SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522
            SE+ALLK  EL  G+    R+R+ K+ EIPFNSTNK+QLSIH   +  +P+HLLVMKGAP
Sbjct: 421  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480

Query: 523  ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582
            ER+L+RCSSIL+ G+E PLDE+ ++AFQ AYL LGGLGERVLGFC L+L ++ +P G+ F
Sbjct: 481  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540

Query: 583  DVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASV 642
            D + +NFP   LCF GL+SMIDPPRA VPDAV KCR+AGI+VIMVTGDHPITAKAIA  V
Sbjct: 541  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600

Query: 643  GIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFA 702
            GIISEG+ETVEDIAARL +PV QVN +DA+ACV++G  LKDM   +L + L+ H E+VFA
Sbjct: 601  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660

Query: 703  RTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILL 762
            RTSPQQKL+IVE CQR GAIVAVTGDGVNDSPALKKADIGVAMGIAGSD +K AADMILL
Sbjct: 661  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720

Query: 763  DDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIE 822
            DDNFASIVTGVE+GRLIFDNLKKSIAYTLT NIPE+TP+LI+I  ++PLPLG +TIL I+
Sbjct: 721  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780

Query: 823  LCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFT 882
            L TD+ P++SLAYE+AESDIM  +PRNPK D+LVNE L + +Y QIG IQ+  GF  YF 
Sbjct: 781  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840

Query: 883  AMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQI 942
             +A+ G+ P+  +GLR  W+D  + D++DSYGQ+WT+ QR   ++TC+T FF+SI V Q 
Sbjct: 841  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900

Query: 943  ADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLV 1002
            AD++I KTRR S FQQG  +NKIL+  +  +  +  FL YCPGM       P++  WW  
Sbjct: 901  ADLVICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFC 959

Query: 1003 PLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035
              PY +LIFVYDE+RKL +R  PG W ++E YY
Sbjct: 960  AFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 1029

 Score = 1246 bits (3224), Expect = 0.0
 Identities = 609/998 (61%), Positives = 770/998 (77%), Gaps = 3/998 (0%)

Query: 38   KRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGT 97
            K+K  +E +KKE+ ++DH+L++ EL  KY    TKG S   A E+L R GPN + PP  T
Sbjct: 35   KQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTT 94

Query: 98   PEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCF 157
            PE+VKF +QL GG   L+W  A +C +A++IQ    +  T DNLYL+I L  VV+VTGCF
Sbjct: 95   PEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCF 154

Query: 158  GYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRIL 217
             YYQE KS+ I+ SFKN+VPQQA VIR G+K QIN  ++V+GDLVE+KGGDRVPAD+R++
Sbjct: 155  SYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLI 214

Query: 218  AAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTI 277
            +AQGCKVDNSSLTGESEPQ+RSP+ THE+PLETRNI FFST C+EGT +G+V+ TGD T+
Sbjct: 215  SAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTV 274

Query: 278  IGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMA 337
            +GRIASL SG+   +TPIA EIEHF+ +I  +A+  G TFF +++ +GY +L A++F + 
Sbjct: 275  MGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIG 334

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGSTS ICSDKTGTLTQNRM
Sbjct: 335  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 394

Query: 398  TVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRI 457
            TV+H+WFD  ++ ADTTE+Q+G+TF +SS+TW  L R+  LCNRA FK+ Q+ +P+ KR 
Sbjct: 395  TVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRA 454

Query: 458  VIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLV 517
              GDASE+ALLKF E +  +    R++ PKV EIPFNSTNK+Q+SIH  ED     H+L+
Sbjct: 455  TTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLRED-SSQTHVLM 513

Query: 518  MKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYP 577
            MKGAPER+LE CS+ L+ GQE  ++++ +EAFQ AYL LGGLGERVLGFC L L    + 
Sbjct: 514  MKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNL-PSSFS 572

Query: 578  PGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKA 637
             G+ F+ + +NFP   LCF GL+SMIDPPRA VPDAV KCR+AGI+VIMVTGDHPITAKA
Sbjct: 573  KGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKA 632

Query: 638  IAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHP 697
            IA  VGIISEG+ET E++AARL++P+ +V+   A+A V++G +LKD+   +L + L+ HP
Sbjct: 633  IAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHP 692

Query: 698  EMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAA 757
            E+VFARTSPQQKL+IVE CQRLGA+VAVTGDGVNDSPALKKADIG+AMGI+GSD +K AA
Sbjct: 693  EIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAA 752

Query: 758  DMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCIT 817
            DMILLDDNFASIVTGVE+GRLIFDNLKKSI YTLT NIPE+TP+L++I + +PLPLG IT
Sbjct: 753  DMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTIT 812

Query: 818  ILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGF 877
            IL I+L TD+ P++SLAYE AESDIM   PRNPK D LVN  L   +Y QIG IQ+ AGF
Sbjct: 813  ILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGF 872

Query: 878  TDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISI 937
              YF  +A+ G+ P+  +G+R  WED +L DL+DSYGQ+WT+ QR   ++TC T FF++I
Sbjct: 873  FTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTI 932

Query: 938  EVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRF 997
             V Q AD++I KTRR S FQQG  RNK+L+  I+ +  +  FL Y PGM       P++ 
Sbjct: 933  VVVQWADLIISKTRRNSLFQQG-MRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKI 991

Query: 998  QWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035
             WWL  +PY ILIFVYDEIRKL +R  P  W ++E YY
Sbjct: 992  TWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
            sapiens]
          Length = 999

 Score =  373 bits (958), Expect = e-103
 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H L  A++ + +  +A  GLS +       R GPN L    G   +     Q    L  +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA   L++F +   E    T       + ++ ++V     G +QE  + + I + K 
Sbjct: 65   LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   VIR   K   +I A  +V GD+VE+  GD+VPAD+R++  +    +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES   T+  E   +      + +N+ F  T    G   G+ V TG  T +G+I S  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
            VE E+TP+  +++ F   ++    +     +++ +        G ++LR  V++    +A
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440
            +V  ++             +   SG T+    E  +               L  +  LCN
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484
             +A    +      K   +G+A+ETAL    E      T   A+   +R           
Sbjct: 422  DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478

Query: 485  FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541
              K   + F+   K  +S++   T   P      + +KGAPE V+ERCSS+ +  +  PL
Sbjct: 479  MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537

Query: 542  DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596
                RE    A +   G G   L    L L  +D PP    D+E  +        + L F
Sbjct: 538  TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593

Query: 597  AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656
             G V M+DPPR  V   + +C  AGIRV+M+TGD+  TA AI   +GI  +     ED+A
Sbjct: 594  VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649

Query: 657  ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716
             +                   G +  D+ P +  +A RT     FAR  P  K  IVE+ 
Sbjct: 650  GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691

Query: 717  QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776
            Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK+AA+M+L DDNFASIV  VE+G
Sbjct: 692  QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750

Query: 777  RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836
            R I+ N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L + 
Sbjct: 751  RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810

Query: 837  KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896
              + DIM   PR+P R+ L+    + + +F+  AI  + G     T  A   WF     G
Sbjct: 811  PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862

Query: 897  LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951
                +    + L+  +D+    G +    +  +      +V  ++IE+C   + L   + 
Sbjct: 863  PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918

Query: 952  RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011
              S  +   + N  L++A+   + +   +   P +P IF   P+  + W+V L   + + 
Sbjct: 919  NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978

Query: 1012 VYDEIRK 1018
            + DE  K
Sbjct: 979  LLDEALK 985


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
            sapiens]
          Length = 1029

 Score =  373 bits (958), Expect = e-103
 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H L  A++ + +  +A  GLS +       R GPN L    G   +     Q    L  +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA   L++F +   E    T       + ++ ++V     G +QE  + + I + K 
Sbjct: 65   LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   VIR   K   +I A  +V GD+VE+  GD+VPAD+R++  +    +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES   T+  E   +      + +N+ F  T    G   G+ V TG  T +G+I S  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
            VE E+TP+  +++ F   ++    +     +++ +        G ++LR  V++    +A
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440
            +V  ++             +   SG T+    E  +               L  +  LCN
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484
             +A    +      K   +G+A+ETAL    E      T   A+   +R           
Sbjct: 422  DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478

Query: 485  FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541
              K   + F+   K  +S++   T   P      + +KGAPE V+ERCSS+ +  +  PL
Sbjct: 479  MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537

Query: 542  DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596
                RE    A +   G G   L    L L  +D PP    D+E  +        + L F
Sbjct: 538  TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593

Query: 597  AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656
             G V M+DPPR  V   + +C  AGIRV+M+TGD+  TA AI   +GI  +     ED+A
Sbjct: 594  VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649

Query: 657  ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716
             +                   G +  D+ P +  +A RT     FAR  P  K  IVE+ 
Sbjct: 650  GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691

Query: 717  QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776
            Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK+AA+M+L DDNFASIV  VE+G
Sbjct: 692  QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750

Query: 777  RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836
            R I+ N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L + 
Sbjct: 751  RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810

Query: 837  KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896
              + DIM   PR+P R+ L+    + + +F+  AI  + G     T  A   WF     G
Sbjct: 811  PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862

Query: 897  LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951
                +    + L+  +D+    G +    +  +      +V  ++IE+C   + L   + 
Sbjct: 863  PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918

Query: 952  RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011
              S  +   + N  L++A+   + +   +   P +P IF   P+  + W+V L   + + 
Sbjct: 919  NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978

Query: 1012 VYDEIRK 1018
            + DE  K
Sbjct: 979  LLDEALK 985


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
            sapiens]
          Length = 998

 Score =  373 bits (958), Expect = e-103
 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H L  A++ + +  +A  GLS +       R GPN L    G   +     Q    L  +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA   L++F +   E    T       + ++ ++V     G +QE  + + I + K 
Sbjct: 65   LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   VIR   K   +I A  +V GD+VE+  GD+VPAD+R++  +    +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES   T+  E   +      + +N+ F  T    G   G+ V TG  T +G+I S  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
            VE E+TP+  +++ F   ++    +     +++ +        G ++LR  V++    +A
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440
            +V  ++             +   SG T+    E  +               L  +  LCN
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484
             +A    +      K   +G+A+ETAL    E      T   A+   +R           
Sbjct: 422  DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478

Query: 485  FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541
              K   + F+   K  +S++   T   P      + +KGAPE V+ERCSS+ +  +  PL
Sbjct: 479  MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537

Query: 542  DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596
                RE    A +   G G   L    L L  +D PP    D+E  +        + L F
Sbjct: 538  TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593

Query: 597  AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656
             G V M+DPPR  V   + +C  AGIRV+M+TGD+  TA AI   +GI  +     ED+A
Sbjct: 594  VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649

Query: 657  ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716
             +                   G +  D+ P +  +A RT     FAR  P  K  IVE+ 
Sbjct: 650  GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691

Query: 717  QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776
            Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK+AA+M+L DDNFASIV  VE+G
Sbjct: 692  QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750

Query: 777  RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836
            R I+ N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L + 
Sbjct: 751  RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810

Query: 837  KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896
              + DIM   PR+P R+ L+    + + +F+  AI  + G     T  A   WF     G
Sbjct: 811  PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862

Query: 897  LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951
                +    + L+  +D+    G +    +  +      +V  ++IE+C   + L   + 
Sbjct: 863  PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918

Query: 952  RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011
              S  +   + N  L++A+   + +   +   P +P IF   P+  + W+V L   + + 
Sbjct: 919  NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978

Query: 1012 VYDEIRK 1018
            + DE  K
Sbjct: 979  LLDEALK 985


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
            sapiens]
          Length = 1029

 Score =  373 bits (958), Expect = e-103
 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H L  A++ + +  +A  GLS +       R GPN L    G   +     Q    L  +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA   L++F +   E    T       + ++ ++V     G +QE  + + I + K 
Sbjct: 65   LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   VIR   K   +I A  +V GD+VE+  GD+VPAD+R++  +    +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES   T+  E   +      + +N+ F  T    G   G+ V TG  T +G+I S  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
            VE E+TP+  +++ F   ++    +     +++ +        G ++LR  V++    +A
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440
            +V  ++             +   SG T+    E  +               L  +  LCN
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484
             +A    +      K   +G+A+ETAL    E      T   A+   +R           
Sbjct: 422  DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478

Query: 485  FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541
              K   + F+   K  +S++   T   P      + +KGAPE V+ERCSS+ +  +  PL
Sbjct: 479  MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537

Query: 542  DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596
                RE    A +   G G   L    L L  +D PP    D+E  +        + L F
Sbjct: 538  TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593

Query: 597  AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656
             G V M+DPPR  V   + +C  AGIRV+M+TGD+  TA AI   +GI  +     ED+A
Sbjct: 594  VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649

Query: 657  ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716
             +                   G +  D+ P +  +A RT     FAR  P  K  IVE+ 
Sbjct: 650  GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691

Query: 717  QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776
            Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK+AA+M+L DDNFASIV  VE+G
Sbjct: 692  QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750

Query: 777  RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836
            R I+ N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L + 
Sbjct: 751  RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810

Query: 837  KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896
              + DIM   PR+P R+ L+    + + +F+  AI  + G     T  A   WF     G
Sbjct: 811  PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862

Query: 897  LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951
                +    + L+  +D+    G +    +  +      +V  ++IE+C   + L   + 
Sbjct: 863  PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918

Query: 952  RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011
              S  +   + N  L++A+   + +   +   P +P IF   P+  + W+V L   + + 
Sbjct: 919  NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978

Query: 1012 VYDEIRK 1018
            + DE  K
Sbjct: 979  LLDEALK 985


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
            sapiens]
          Length = 1043

 Score =  373 bits (958), Expect = e-103
 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H L  A++ + +  +A  GLS +       R GPN L    G   +     Q    L  +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA   L++F +   E    T       + ++ ++V     G +QE  + + I + K 
Sbjct: 65   LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   VIR   K   +I A  +V GD+VE+  GD+VPAD+R++  +    +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES   T+  E   +      + +N+ F  T    G   G+ V TG  T +G+I S  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
            VE E+TP+  +++ F   ++    +     +++ +        G ++LR  V++    +A
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440
            +V  ++             +   SG T+    E  +               L  +  LCN
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484
             +A    +      K   +G+A+ETAL    E      T   A+   +R           
Sbjct: 422  DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478

Query: 485  FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541
              K   + F+   K  +S++   T   P      + +KGAPE V+ERCSS+ +  +  PL
Sbjct: 479  MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537

Query: 542  DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596
                RE    A +   G G   L    L L  +D PP    D+E  +        + L F
Sbjct: 538  TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593

Query: 597  AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656
             G V M+DPPR  V   + +C  AGIRV+M+TGD+  TA AI   +GI  +     ED+A
Sbjct: 594  VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649

Query: 657  ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716
             +                   G +  D+ P +  +A RT     FAR  P  K  IVE+ 
Sbjct: 650  GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691

Query: 717  QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776
            Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK+AA+M+L DDNFASIV  VE+G
Sbjct: 692  QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750

Query: 777  RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836
            R I+ N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L + 
Sbjct: 751  RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810

Query: 837  KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896
              + DIM   PR+P R+ L+    + + +F+  AI  + G     T  A   WF     G
Sbjct: 811  PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862

Query: 897  LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951
                +    + L+  +D+    G +    +  +      +V  ++IE+C   + L   + 
Sbjct: 863  PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918

Query: 952  RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011
              S  +   + N  L++A+   + +   +   P +P IF   P+  + W+V L   + + 
Sbjct: 919  NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978

Query: 1012 VYDEIRK 1018
            + DE  K
Sbjct: 979  LLDEALK 985


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
            sapiens]
          Length = 1044

 Score =  373 bits (958), Expect = e-103
 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H L  A++ + +  +A  GLS +       R GPN L    G   +     Q    L  +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA   L++F +   E    T       + ++ ++V     G +QE  + + I + K 
Sbjct: 65   LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   VIR   K   +I A  +V GD+VE+  GD+VPAD+R++  +    +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES   T+  E   +      + +N+ F  T    G   G+ V TG  T +G+I S  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
            VE E+TP+  +++ F   ++    +     +++ +        G ++LR  V++    +A
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440
            +V  ++             +   SG T+    E  +               L  +  LCN
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484
             +A    +      K   +G+A+ETAL    E      T   A+   +R           
Sbjct: 422  DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478

Query: 485  FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541
              K   + F+   K  +S++   T   P      + +KGAPE V+ERCSS+ +  +  PL
Sbjct: 479  MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537

Query: 542  DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596
                RE    A +   G G   L    L L  +D PP    D+E  +        + L F
Sbjct: 538  TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593

Query: 597  AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656
             G V M+DPPR  V   + +C  AGIRV+M+TGD+  TA AI   +GI  +     ED+A
Sbjct: 594  VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649

Query: 657  ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716
             +                   G +  D+ P +  +A RT     FAR  P  K  IVE+ 
Sbjct: 650  GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691

Query: 717  QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776
            Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK+AA+M+L DDNFASIV  VE+G
Sbjct: 692  QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750

Query: 777  RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836
            R I+ N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L + 
Sbjct: 751  RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810

Query: 837  KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896
              + DIM   PR+P R+ L+    + + +F+  AI  + G     T  A   WF     G
Sbjct: 811  PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862

Query: 897  LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951
                +    + L+  +D+    G +    +  +      +V  ++IE+C   + L   + 
Sbjct: 863  PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918

Query: 952  RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011
              S  +   + N  L++A+   + +   +   P +P IF   P+  + W+V L   + + 
Sbjct: 919  NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978

Query: 1012 VYDEIRK 1018
            + DE  K
Sbjct: 979  LLDEALK 985


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
            sapiens]
          Length = 1052

 Score =  373 bits (958), Expect = e-103
 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H L  A++ + +  +A  GLS +       R GPN L    G   +     Q    L  +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA   L++F +   E    T       + ++ ++V     G +QE  + + I + K 
Sbjct: 65   LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   VIR   K   +I A  +V GD+VE+  GD+VPAD+R++  +    +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES   T+  E   +      + +N+ F  T    G   G+ V TG  T +G+I S  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
            VE E+TP+  +++ F   ++    +     +++ +        G ++LR  V++    +A
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440
            +V  ++             +   SG T+    E  +               L  +  LCN
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484
             +A    +      K   +G+A+ETAL    E      T   A+   +R           
Sbjct: 422  DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478

Query: 485  FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541
              K   + F+   K  +S++   T   P      + +KGAPE V+ERCSS+ +  +  PL
Sbjct: 479  MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537

Query: 542  DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596
                RE    A +   G G   L    L L  +D PP    D+E  +        + L F
Sbjct: 538  TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593

Query: 597  AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656
             G V M+DPPR  V   + +C  AGIRV+M+TGD+  TA AI   +GI  +     ED+A
Sbjct: 594  VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649

Query: 657  ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716
             +                   G +  D+ P +  +A RT     FAR  P  K  IVE+ 
Sbjct: 650  GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691

Query: 717  QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776
            Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK+AA+M+L DDNFASIV  VE+G
Sbjct: 692  QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750

Query: 777  RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836
            R I+ N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L + 
Sbjct: 751  RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810

Query: 837  KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896
              + DIM   PR+P R+ L+    + + +F+  AI  + G     T  A   WF     G
Sbjct: 811  PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862

Query: 897  LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951
                +    + L+  +D+    G +    +  +      +V  ++IE+C   + L   + 
Sbjct: 863  PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918

Query: 952  RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011
              S  +   + N  L++A+   + +   +   P +P IF   P+  + W+V L   + + 
Sbjct: 919  NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978

Query: 1012 VYDEIRK 1018
            + DE  K
Sbjct: 979  LLDEALK 985


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
            sapiens]
          Length = 997

 Score =  371 bits (953), Expect = e-102
 Identities = 304/1034 (29%), Positives = 482/1034 (46%), Gaps = 112/1034 (10%)

Query: 53   NDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQ 112
            N H  +V E+   +  + + GLS     +L  R G N L    G         Q    L 
Sbjct: 3    NAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLV 62

Query: 113  CLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASF 172
             ++ +AA I  +    +  E  +T     ++   ++ ++V     G +QE  + N I + 
Sbjct: 63   RILLLAACISFVLAWFEEGEETITAFVEPFV---ILLILVANAIVGVWQERNAENAIEAL 119

Query: 173  KNLVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSS 228
            K   P+   V R   K   +I A  +V GD+VE+  GD+VPADIR+ + +    +VD S 
Sbjct: 120  KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179

Query: 229  LTGESEPQTRSPECTHESPL--------ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGR 280
            LTGES    +     H  P+        + +N+ F  T    G   G+VV TG  T IG+
Sbjct: 180  LTGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGK 234

Query: 281  IASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVF 334
            I       E E+TP+  +++ F + ++ +  L     +I+ +        G +++R  ++
Sbjct: 235  IRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIY 294

Query: 335  F----MAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTG 390
            +    +A+ VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTG
Sbjct: 295  YFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTG 354

Query: 391  TLTQNRMTVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALC 433
            TLT N+M+V  ++  + +     + ++   +G T+    E  +               L 
Sbjct: 355  TLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414

Query: 434  RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETAL-------------LK-FSELTLGNAM 479
             +  LCN +A    +      K   +G+A+ETAL             LK  S++   NA 
Sbjct: 415  TICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANAC 471

Query: 480  G--YRDRFPKVCEIPFNSTNKFQLSIHTLEDP-RDPRHLLVMKGAPERVLERCSSILIKG 536
                +    K   + F+   K      T   P R     + +KGAPE V++RC+ I +  
Sbjct: 472  NSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531

Query: 537  QELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNF--PSSGL 594
             ++P+    ++   +     G  G   L    L  ++           ++ NF    + L
Sbjct: 532  TKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNL 590

Query: 595  CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654
             F G V M+DPPR  V  +V  CR AGIRVIM+TGD+  TA AI   +GI  +     ED
Sbjct: 591  TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----ED 646

Query: 655  IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714
            + ++                   G +  +++PS   +A        FAR  P  K  IVE
Sbjct: 647  VTSK----------------AFTGREFDELNPSAQRDACLN--ARCFARVEPSHKSKIVE 688

Query: 715  SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774
              Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK A++M+L DDNF++IV  VE
Sbjct: 689  FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747

Query: 775  QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834
            +GR I++N+K+ I Y ++ N+ E+    +   +  P  L  + +L++ L TD  P+ +L 
Sbjct: 748  EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807

Query: 835  YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893
            +   + DIM+  PRNPK      EPL + + +F+  AI  + G     T  A   WF   
Sbjct: 808  FNPPDLDIMNKPPRNPK------EPLISGWLFFRYLAIGCYVGAA---TVGAAAWWFIAA 858

Query: 894  CVGLRAQWE--DHHLQ---DLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIR 948
              G R  +    H LQ   D  D  G +    +  Y      +V  ++IE+C   + L  
Sbjct: 859  DGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSV-LVTIEMCNALNSL-- 915

Query: 949  KTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGI 1008
             +   S  +   + N  LV +I   + +   + Y   +P IF   P+    WL+ L   +
Sbjct: 916  -SENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974

Query: 1009 LIFVYDEIRKLGVR 1022
             + + DE  K   R
Sbjct: 975  PVILMDETLKFVAR 988


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
            sapiens]
          Length = 1042

 Score =  371 bits (953), Expect = e-102
 Identities = 304/1034 (29%), Positives = 482/1034 (46%), Gaps = 112/1034 (10%)

Query: 53   NDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQ 112
            N H  +V E+   +  + + GLS     +L  R G N L    G         Q    L 
Sbjct: 3    NAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLV 62

Query: 113  CLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASF 172
             ++ +AA I  +    +  E  +T     ++   ++ ++V     G +QE  + N I + 
Sbjct: 63   RILLLAACISFVLAWFEEGEETITAFVEPFV---ILLILVANAIVGVWQERNAENAIEAL 119

Query: 173  KNLVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSS 228
            K   P+   V R   K   +I A  +V GD+VE+  GD+VPADIR+ + +    +VD S 
Sbjct: 120  KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179

Query: 229  LTGESEPQTRSPECTHESPL--------ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGR 280
            LTGES    +     H  P+        + +N+ F  T    G   G+VV TG  T IG+
Sbjct: 180  LTGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGK 234

Query: 281  IASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVF 334
            I       E E+TP+  +++ F + ++ +  L     +I+ +        G +++R  ++
Sbjct: 235  IRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIY 294

Query: 335  F----MAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTG 390
            +    +A+ VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTG
Sbjct: 295  YFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTG 354

Query: 391  TLTQNRMTVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALC 433
            TLT N+M+V  ++  + +     + ++   +G T+    E  +               L 
Sbjct: 355  TLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414

Query: 434  RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETAL-------------LK-FSELTLGNAM 479
             +  LCN +A    +      K   +G+A+ETAL             LK  S++   NA 
Sbjct: 415  TICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANAC 471

Query: 480  G--YRDRFPKVCEIPFNSTNKFQLSIHTLEDP-RDPRHLLVMKGAPERVLERCSSILIKG 536
                +    K   + F+   K      T   P R     + +KGAPE V++RC+ I +  
Sbjct: 472  NSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531

Query: 537  QELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNF--PSSGL 594
             ++P+    ++   +     G  G   L    L  ++           ++ NF    + L
Sbjct: 532  TKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNL 590

Query: 595  CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654
             F G V M+DPPR  V  +V  CR AGIRVIM+TGD+  TA AI   +GI  +     ED
Sbjct: 591  TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----ED 646

Query: 655  IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714
            + ++                   G +  +++PS   +A        FAR  P  K  IVE
Sbjct: 647  VTSK----------------AFTGREFDELNPSAQRDACLN--ARCFARVEPSHKSKIVE 688

Query: 715  SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774
              Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK A++M+L DDNF++IV  VE
Sbjct: 689  FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747

Query: 775  QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834
            +GR I++N+K+ I Y ++ N+ E+    +   +  P  L  + +L++ L TD  P+ +L 
Sbjct: 748  EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807

Query: 835  YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893
            +   + DIM+  PRNPK      EPL + + +F+  AI  + G     T  A   WF   
Sbjct: 808  FNPPDLDIMNKPPRNPK------EPLISGWLFFRYLAIGCYVGAA---TVGAAAWWFIAA 858

Query: 894  CVGLRAQWE--DHHLQ---DLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIR 948
              G R  +    H LQ   D  D  G +    +  Y      +V  ++IE+C   + L  
Sbjct: 859  DGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSV-LVTIEMCNALNSL-- 915

Query: 949  KTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGI 1008
             +   S  +   + N  LV +I   + +   + Y   +P IF   P+    WL+ L   +
Sbjct: 916  -SENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974

Query: 1009 LIFVYDEIRKLGVR 1022
             + + DE  K   R
Sbjct: 975  PVILMDETLKFVAR 988


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score =  356 bits (913), Expect = 7e-98
 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%)

Query: 56  QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115
           +L V+E+    Q     GL+    +      G N        P + K+  Q    L  L+
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175
             +A I ++             DD + + +A++ VV V     + QE++S   +     L
Sbjct: 88  LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134

Query: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235
           VP +   +R+G      A  LV GD V +  GDRVPAD+R+  A    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291
            ++     P  T+       NIAF  T+   G  +G+V+ TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351
           KTP+   ++     ++  +        +V   +G   L      +++ VA +PEGL   V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411
           TV L+L   R+  K  +VK L  VETLG  +VICSDKTGTLT+N MTV+H++  + +H  
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462
            T    +Q G+              A+ R++    +CN A  ++           ++G  
Sbjct: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425

Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522
           +E AL+  + + +G   G +  + +  E PF+S  K+          +D   +  MKGA 
Sbjct: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483

Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582
           E+V++ C++   KGQ L L +Q R+ +Q     +G  G RVL                  
Sbjct: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528

Query: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641
                + P  G L F GLV +IDPPR  V +AV     +G+ + M+TGD   TA AIA+ 
Sbjct: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583

Query: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700
           +G+ S+ S++V                        +G ++  MD  +L + +   P++ V
Sbjct: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616

Query: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760
           F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+D  K AADMI
Sbjct: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676

Query: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820
           L+DD+F +I++ +E+G+ I++N+K  + + L+ +I  LT   +   ++ P PL  + IL+
Sbjct: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736

Query: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851
           I +  D  P+ SL  E  + D++   PRN K
Sbjct: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score =  356 bits (913), Expect = 7e-98
 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%)

Query: 56  QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115
           +L V+E+    Q     GL+    +      G N        P + K+  Q    L  L+
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175
             +A I ++             DD + + +A++ VV V     + QE++S   +     L
Sbjct: 88  LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134

Query: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235
           VP +   +R+G      A  LV GD V +  GDRVPAD+R+  A    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291
            ++     P  T+       NIAF  T+   G  +G+V+ TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351
           KTP+   ++     ++  +        +V   +G   L      +++ VA +PEGL   V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411
           TV L+L   R+  K  +VK L  VETLG  +VICSDKTGTLT+N MTV+H++  + +H  
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462
            T    +Q G+              A+ R++    +CN A  ++           ++G  
Sbjct: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425

Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522
           +E AL+  + + +G   G +  + +  E PF+S  K+          +D   +  MKGA 
Sbjct: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483

Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582
           E+V++ C++   KGQ L L +Q R+ +Q     +G  G RVL                  
Sbjct: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528

Query: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641
                + P  G L F GLV +IDPPR  V +AV     +G+ + M+TGD   TA AIA+ 
Sbjct: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583

Query: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700
           +G+ S+ S++V                        +G ++  MD  +L + +   P++ V
Sbjct: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616

Query: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760
           F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+D  K AADMI
Sbjct: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676

Query: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820
           L+DD+F +I++ +E+G+ I++N+K  + + L+ +I  LT   +   ++ P PL  + IL+
Sbjct: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736

Query: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851
           I +  D  P+ SL  E  + D++   PRN K
Sbjct: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score =  356 bits (913), Expect = 7e-98
 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%)

Query: 56  QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115
           +L V+E+    Q     GL+    +      G N        P + K+  Q    L  L+
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175
             +A I ++             DD + + +A++ VV V     + QE++S   +     L
Sbjct: 88  LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134

Query: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235
           VP +   +R+G      A  LV GD V +  GDRVPAD+R+  A    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291
            ++     P  T+       NIAF  T+   G  +G+V+ TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351
           KTP+   ++     ++  +        +V   +G   L      +++ VA +PEGL   V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411
           TV L+L   R+  K  +VK L  VETLG  +VICSDKTGTLT+N MTV+H++  + +H  
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462
            T    +Q G+              A+ R++    +CN A  ++           ++G  
Sbjct: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425

Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522
           +E AL+  + + +G   G +  + +  E PF+S  K+          +D   +  MKGA 
Sbjct: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483

Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582
           E+V++ C++   KGQ L L +Q R+ +Q     +G  G RVL                  
Sbjct: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528

Query: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641
                + P  G L F GLV +IDPPR  V +AV     +G+ + M+TGD   TA AIA+ 
Sbjct: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583

Query: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700
           +G+ S+ S++V                        +G ++  MD  +L + +   P++ V
Sbjct: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616

Query: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760
           F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+D  K AADMI
Sbjct: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676

Query: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820
           L+DD+F +I++ +E+G+ I++N+K  + + L+ +I  LT   +   ++ P PL  + IL+
Sbjct: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736

Query: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851
           I +  D  P+ SL  E  + D++   PRN K
Sbjct: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score =  356 bits (913), Expect = 7e-98
 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%)

Query: 56  QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115
           +L V+E+    Q     GL+    +      G N        P + K+  Q    L  L+
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175
             +A I ++             DD + + +A++ VV V     + QE++S   +     L
Sbjct: 88  LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134

Query: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235
           VP +   +R+G      A  LV GD V +  GDRVPAD+R+  A    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291
            ++     P  T+       NIAF  T+   G  +G+V+ TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351
           KTP+   ++     ++  +        +V   +G   L      +++ VA +PEGL   V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411
           TV L+L   R+  K  +VK L  VETLG  +VICSDKTGTLT+N MTV+H++  + +H  
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462
            T    +Q G+              A+ R++    +CN A  ++           ++G  
Sbjct: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425

Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522
           +E AL+  + + +G   G +  + +  E PF+S  K+          +D   +  MKGA 
Sbjct: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483

Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582
           E+V++ C++   KGQ L L +Q R+ +Q     +G  G RVL                  
Sbjct: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528

Query: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641
                + P  G L F GLV +IDPPR  V +AV     +G+ + M+TGD   TA AIA+ 
Sbjct: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583

Query: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700
           +G+ S+ S++V                        +G ++  MD  +L + +   P++ V
Sbjct: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616

Query: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760
           F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+D  K AADMI
Sbjct: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676

Query: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820
           L+DD+F +I++ +E+G+ I++N+K  + + L+ +I  LT   +   ++ P PL  + IL+
Sbjct: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736

Query: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851
           I +  D  P+ SL  E  + D++   PRN K
Sbjct: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo
            sapiens]
          Length = 994

 Score =  356 bits (913), Expect = 7e-98
 Identities = 303/1033 (29%), Positives = 476/1033 (46%), Gaps = 113/1033 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H  +  E    +  S T GL+       L + G N L    G   +     Q    L  +
Sbjct: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA I  +    +  E  +T     ++   ++ +++     G +QE  + N I + K 
Sbjct: 65   LLLAACISFVLAWFEEGEETITAFVEPFV---ILLILIANAIVGVWQERNAENAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   V R   K   +I A  +V GD+VE+  GD+VPADIRILA +    +VD S LT
Sbjct: 122  YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES    +  E   +      + +N+ F  T    G   G+V  TG  T IG+I    + 
Sbjct: 182  GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
             E +KTP+  +++ F + ++ +  L     +++ +        G ++ R  +++    +A
Sbjct: 242  TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCN 440
            +V  ++  + +       ++   +G T+    E  +               L  +  LCN
Sbjct: 362  SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDRFPKVCEIPFNS 495
             ++    +      K   +G+A+ETAL    E      T   ++   +R    C      
Sbjct: 422  DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVER-ANACNSVIRQ 477

Query: 496  TNKFQLSIHTLEDPRDPRHLLV-----------------MKGAPERVLERCSSILIKGQE 538
              K +    TLE  RD + + V                 +KGAPE V++RC+ + +    
Sbjct: 478  LMKKEF---TLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTR 534

Query: 539  LPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPG---YAFDVEAMNFP-SSGL 594
            +PL    +E    A +   G G   L    L L  +D PP       D  A      + L
Sbjct: 535  VPLTGPVKEKIM-AVIKEWGTGRDTLRC--LALATRDTPPKREEMVLDDSARFLEYETDL 591

Query: 595  CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654
             F G+V M+DPPR  V  ++  CR AGIRVIM+TGD+  TA AI   +GI  E     E+
Sbjct: 592  TFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGEN----EE 647

Query: 655  IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714
            +A R                   G +  D+  +E  EA R      FAR  P  K  IVE
Sbjct: 648  VADR----------------AYTGREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVE 689

Query: 715  SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774
              Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK A++M+L DDNF++IV  VE
Sbjct: 690  YLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 748

Query: 775  QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834
            +GR I++N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L 
Sbjct: 749  EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALG 808

Query: 835  YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893
            +   + DIM   PR+PK      EPL + + +F+  AI  + G     T  A   WF   
Sbjct: 809  FNPPDLDIMDRPPRSPK------EPLISGWLFFRYMAIGGYVGAA---TVGAAAWWFLYA 859

Query: 894  CVGLRAQWED--HHLQDLQDSYGQEWTFGQ--RLYQQYTCYTVFFISIEVCQIADVLIRK 949
              G    +    H +Q  +D+   E    +     +  T      ++IE+C   + L   
Sbjct: 860  EDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSL--- 916

Query: 950  TRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGIL 1009
            +   S  +   + N  L+ +I   + +   + Y   +P IF    +    WL+ L   + 
Sbjct: 917  SENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLP 976

Query: 1010 IFVYDEIRKLGVR 1022
            +   DEI K   R
Sbjct: 977  VIGLDEILKFVAR 989


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo
            sapiens]
          Length = 1001

 Score =  356 bits (913), Expect = 7e-98
 Identities = 303/1033 (29%), Positives = 476/1033 (46%), Gaps = 113/1033 (10%)

Query: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114
            H  +  E    +  S T GL+       L + G N L    G   +     Q    L  +
Sbjct: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64

Query: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174
            + +AA I  +    +  E  +T     ++   ++ +++     G +QE  + N I + K 
Sbjct: 65   LLLAACISFVLAWFEEGEETITAFVEPFV---ILLILIANAIVGVWQERNAENAIEALKE 121

Query: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230
              P+   V R   K   +I A  +V GD+VE+  GD+VPADIRILA +    +VD S LT
Sbjct: 122  YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181

Query: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287
            GES    +  E   +      + +N+ F  T    G   G+V  TG  T IG+I    + 
Sbjct: 182  GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241

Query: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337
             E +KTP+  +++ F + ++ +  L     +++ +        G ++ R  +++    +A
Sbjct: 242  TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301

Query: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCN 440
            +V  ++  + +       ++   +G T+    E  +               L  +  LCN
Sbjct: 362  SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421

Query: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDRFPKVCEIPFNS 495
             ++    +      K   +G+A+ETAL    E      T   ++   +R    C      
Sbjct: 422  DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVER-ANACNSVIRQ 477

Query: 496  TNKFQLSIHTLEDPRDPRHLLV-----------------MKGAPERVLERCSSILIKGQE 538
              K +    TLE  RD + + V                 +KGAPE V++RC+ + +    
Sbjct: 478  LMKKEF---TLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTR 534

Query: 539  LPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPG---YAFDVEAMNFP-SSGL 594
            +PL    +E    A +   G G   L    L L  +D PP       D  A      + L
Sbjct: 535  VPLTGPVKEKIM-AVIKEWGTGRDTLRC--LALATRDTPPKREEMVLDDSARFLEYETDL 591

Query: 595  CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654
             F G+V M+DPPR  V  ++  CR AGIRVIM+TGD+  TA AI   +GI  E     E+
Sbjct: 592  TFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGEN----EE 647

Query: 655  IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714
            +A R                   G +  D+  +E  EA R      FAR  P  K  IVE
Sbjct: 648  VADR----------------AYTGREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVE 689

Query: 715  SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774
              Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK A++M+L DDNF++IV  VE
Sbjct: 690  YLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 748

Query: 775  QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834
            +GR I++N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L 
Sbjct: 749  EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALG 808

Query: 835  YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893
            +   + DIM   PR+PK      EPL + + +F+  AI  + G     T  A   WF   
Sbjct: 809  FNPPDLDIMDRPPRSPK------EPLISGWLFFRYMAIGGYVGAA---TVGAAAWWFLYA 859

Query: 894  CVGLRAQWED--HHLQDLQDSYGQEWTFGQ--RLYQQYTCYTVFFISIEVCQIADVLIRK 949
              G    +    H +Q  +D+   E    +     +  T      ++IE+C   + L   
Sbjct: 860  EDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSL--- 916

Query: 950  TRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGIL 1009
            +   S  +   + N  L+ +I   + +   + Y   +P IF    +    WL+ L   + 
Sbjct: 917  SENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLP 976

Query: 1010 IFVYDEIRKLGVR 1022
            +   DEI K   R
Sbjct: 977  VIGLDEILKFVAR 989


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo
            sapiens]
          Length = 1015

 Score =  344 bits (882), Expect = 3e-94
 Identities = 290/1024 (28%), Positives = 468/1024 (45%), Gaps = 119/1024 (11%)

Query: 53   NDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQ 112
            N H  +V E+   +  + + GLS     +L  R G N L    G         Q    L 
Sbjct: 3    NAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLV 62

Query: 113  CLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASF 172
             ++ +AA I  +    +  E  +T     ++   ++ ++V     G +QE  + N I + 
Sbjct: 63   RILLLAACISFVLAWFEEGEETITAFVEPFV---ILLILVANAIVGVWQERNAENAIEAL 119

Query: 173  KNLVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLT 230
            K   P+   V R   K   +I A  +V GD+VE+ G                  ++ S+ 
Sbjct: 120  KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVI 161

Query: 231  GESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVEN 290
              ++P    P   ++   + +N+ F  T    G   G+VV TG  T IG+I       E 
Sbjct: 162  KHTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ 217

Query: 291  EKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MAIVV 340
            E+TP+  +++ F + ++ +  L     +I+ +        G +++R  +++    +A+ V
Sbjct: 218  ERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 277

Query: 341  AYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVS 400
            A +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M+V 
Sbjct: 278  AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 337

Query: 401  HLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCNRAA 443
             ++  + +     + ++   +G T+    E  +               L  +  LCN +A
Sbjct: 338  RMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397

Query: 444  FKSGQDAVPVPKRIVIGDASETAL-------------LK-FSELTLGNAMG--YRDRFPK 487
                +      K   +G+A+ETAL             LK  S++   NA     +    K
Sbjct: 398  LDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 454

Query: 488  VCEIPFNSTNKFQLSIHTLEDP-RDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWR 546
               + F+   K      T   P R     + +KGAPE V++RC+ I +   ++P+    +
Sbjct: 455  EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 514

Query: 547  EAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNF--PSSGLCFAGLVSMID 604
            +   +     G  G   L    L  ++           ++ NF    + L F G V M+D
Sbjct: 515  QKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 573

Query: 605  PPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVD 664
            PPR  V  +V  CR AGIRVIM+TGD+  TA AI   +GI  +     ED+ ++      
Sbjct: 574  PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTSK------ 623

Query: 665  QVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVA 724
                         G +  +++PS   +A        FAR  P  K  IVE  Q    I A
Sbjct: 624  ----------AFTGREFDELNPSAQRDACLN--ARCFARVEPSHKSKIVEFLQSFDEITA 671

Query: 725  VTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLK 784
            +TGDGVND+PALKKA+IG+AMG +G+  AK A++M+L DDNF++IV  VE+GR I++N+K
Sbjct: 672  MTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK 730

Query: 785  KSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMH 844
            + I Y ++ N+ E+    +   +  P  L  + +L++ L TD  P+ +L +   + DIM+
Sbjct: 731  QFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMN 790

Query: 845  LRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWE- 902
              PRNPK      EPL + + +F+  AI  + G     T  A   WF     G R  +  
Sbjct: 791  KPPRNPK------EPLISGWLFFRYLAIGCYVGAA---TVGAAAWWFIAADGGPRVSFYQ 841

Query: 903  -DHHLQ---DLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQ 958
              H LQ   D  D  G +    +  Y      +V  ++IE+C   + L   +   S  + 
Sbjct: 842  LSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSV-LVTIEMCNALNSL---SENQSLLRM 897

Query: 959  GFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRK 1018
              + N  LV +I   + +   + Y   +P IF   P+    WL+ L   + + + DE  K
Sbjct: 898  PPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLK 957

Query: 1019 LGVR 1022
               R
Sbjct: 958  FVAR 961


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
           sapiens]
          Length = 946

 Score =  331 bits (848), Expect = 2e-90
 Identities = 269/864 (31%), Positives = 405/864 (46%), Gaps = 101/864 (11%)

Query: 29  KKKAGGGGGKRKEKLENMKKEMEINDH-QLSVAELEQKYQTSATK--------------- 72
           KK    GGG++ + LE  ++E  I++  +L   E E+K      K               
Sbjct: 11  KKLGFSGGGRQYQALEKDEEEALIDEQSELKAIEKEKKVTALPPKEACKCQKEDLARAFC 70

Query: 73  -----GLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFA 127
                GLS     +  L  G N        P + K+  Q    L  L+  +A + +    
Sbjct: 71  VDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSALVSV---- 126

Query: 128 IQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGD 187
                  LT +    ++IA   +VVVT  F   QE++S   +     +VP +   +R+G 
Sbjct: 127 -------LTKEYEDAVSIATAVLVVVTVAF--IQEYRSEKSLEELTKMVPPECNCLREGK 177

Query: 188 KFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP--QTRSPECTHE 245
              + A +LV GD+V +  GDR+PADIR+       VD SS TGE+EP  +T SP     
Sbjct: 178 LQHLLARELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGG 237

Query: 246 SPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDI 305
                 NI F  T+   G  QG+V+ TG+ +  G +  +    E  KTP+    +  +D 
Sbjct: 238 DLTTLSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPL----QKSMDR 293

Query: 306 IAGLAILFGATFFIVAMCIGYT----FLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKR 361
           +     LF      + M IG++     L      +++ VA +PEGL   V V L L   R
Sbjct: 294 LGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLR 353

Query: 362 LASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQ- 420
           +A K  +VK L  VETLG  SV+CSDKTGTLT N MTV+ L   + +    +     GQ 
Sbjct: 354 MAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQG 413

Query: 421 --TFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFS-ELTLGN 477
                 S E  +    V       A     +AV + K  V+G  +E AL+  + ++ L +
Sbjct: 414 TVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAV-IRKNAVMGQPTEGALMALAMKMDLSD 472

Query: 478 AMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQ 537
               ++ + +  EIPF+S  K+ +++       D   +  MKGA E V+  C+     G 
Sbjct: 473 I---KNSYIRKKEIPFSSEQKW-MAVKCSLKTEDQEDIYFMKGALEEVIRYCTMYNNGGI 528

Query: 538 ELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSG-LCF 596
            LPL  Q R         +G LG RVL                       + P  G L F
Sbjct: 529 PLPLTPQQRSFCLQEEKRMGSLGLRVLALA--------------------SGPELGRLTF 568

Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656
            GLV +IDPPR  V +AV     +G+ V M+TGD   TA AI  ++G+ +          
Sbjct: 569 LGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLCN---------- 618

Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716
                          +   ++G ++  ++  EL +  R     VF RTSP+ KL I+++ 
Sbjct: 619 --------------GKLQAMSGEEVDSVEKGELAD--RVGKVSVFFRTSPKHKLKIIKAL 662

Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776
           Q  GAIVA+TGDGVND+ ALK ADIG+AMG  G+D +K AA+MIL+DD+F++I+  VE+G
Sbjct: 663 QESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNAVEEG 722

Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836
           + IF N+K  + + L+ +I  L+   +    ++P PL  + IL+I +  D  P+ SL  E
Sbjct: 723 KGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLGVE 782

Query: 837 KAESDIMHLRPRNPKRDRLVNEPL 860
             + D     PR+  RD +++  L
Sbjct: 783 PVDKDAFRQPPRS-VRDTILSRAL 805


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
          Length = 1198

 Score =  253 bits (645), Expect = 9e-67
 Identities = 251/958 (26%), Positives = 421/958 (43%), Gaps = 163/958 (17%)

Query: 143  LAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLV 202
            + +++I VV+VT    + +E +   + +  +    Q+ TV+R G   QI   ++VVGD+ 
Sbjct: 157  ILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVVRAGQVVQIPVAEIVVGDIA 214

Query: 203  EMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLE 262
            ++K GD +PAD   +     K+D SSLTGES+   +S +   + P+         T  +E
Sbjct: 215  QVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-----LLSGTHVME 266

Query: 263  GTVQGLVVNTGDRTIIGRIASL--ASGVENEK---------------------------- 292
            G+ + LV   G  +  G I +L  A G E EK                            
Sbjct: 267  GSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDAD 326

Query: 293  -------------------TPIAIEIEHFVDIIAGLAILFGATFFIV------------- 320
                               T +A++I     +++ + ++    +F V             
Sbjct: 327  DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPE 386

Query: 321  --AMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETL 378
               + + Y F++  +  + ++V  VPEGL   VT+ L+ + K++   N +V++L+A ET+
Sbjct: 387  CTPVYVQY-FVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETM 445

Query: 379  GSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTL 438
            G+ + ICSDKTGTLT NRMTV   +  + +H  +  +  S  T     +T   L   + +
Sbjct: 446  GNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSSINT-----KTMELLINAIAI 499

Query: 439  CNRAAFK--SGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNST 496
             +    K    +    +P++  +G+ +E  LL F      +    R + P+       + 
Sbjct: 500  NSAYTTKILPPEKEGALPRQ--VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTF 557

Query: 497  NKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL------DEQWREAFQ 550
            N  + S+ T+    D    +  KGA E VL++C  IL    E  +      DE  ++  +
Sbjct: 558  NSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE 617

Query: 551  TAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATV 610
               ++  GL       C  Y   +D+P     D +  N   + L    +V + DP R  V
Sbjct: 618  P--MACDGLRT----ICVAY---RDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEV 668

Query: 611  PDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETV----EDIAARLRVPVDQV 666
            P+A+ KC+ AGI V MVTGD+  TA+AIA   GII  G + +    ++   R+R      
Sbjct: 669  PEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIR------ 722

Query: 667  NRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC-----QRLGA 721
            N K          +++     ++   LR     V AR+SP  K  +V+            
Sbjct: 723  NEKG---------EIEQERIDKIWPKLR-----VLARSSPTDKHTLVKGIIDSTHTEQRQ 768

Query: 722  IVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFD 781
            +VAVTGDG ND PALKKAD+G AMGIAG+D AK A+D+IL DDNF+SIV  V  GR ++D
Sbjct: 769  VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYD 828

Query: 782  NLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESD 841
            ++ K + + LT N+  +        ++   PL  + +L++ L  D F S++LA E     
Sbjct: 829  SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTET 888

Query: 842  IMHLRP---RNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLR 898
            ++  +P     P   R + + +  ++ +Q+  I                  F LL VG +
Sbjct: 889  LLLRKPYGRNKPLISRTMMKNILGHAVYQLALI------------------FTLLFVGEK 930

Query: 899  AQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQ 958
                       Q   G+         + YT     F+ +++    ++  RK         
Sbjct: 931  M---------FQIDSGRNAPLHSPPSEHYTIIFNTFVMMQL--FNEINARKIHGERNVFD 979

Query: 959  GFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEI 1016
            G FRN I    ++    I   +    G P  F+  P++   W+  +  G+   V+ ++
Sbjct: 980  GIFRNPIFCTIVLGTFAIQIVIVQFGGKP--FSCSPLQLDQWMWCIFIGLGELVWGQV 1035


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
           sapiens]
          Length = 1170

 Score =  223 bits (567), Expect = 9e-58
 Identities = 173/559 (30%), Positives = 277/559 (49%), Gaps = 54/559 (9%)

Query: 328 FLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSD 387
           F++  +  + ++V  VPEGL   VT+ L+ + K++   N +V++L+A ET+G+ + ICSD
Sbjct: 406 FVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSD 465

Query: 388 KTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLC-NRAAFKS 446
           KTGTLT NRMTV   +               G  + Q       L +VL L  N  +  S
Sbjct: 466 KTGTLTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINS 512

Query: 447 GQDAVPVPKRIV------IGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQ 500
              +  +P          +G+ +E ALL F      +    R+  P+       + N  +
Sbjct: 513 AYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVR 572

Query: 501 LSIHTLEDPRDPRHLLVMKGAPERVLERCSSILI-KGQELPLDEQWREAF-QTAYLSLGG 558
            S+ T+    +    +  KGA E +L +C+ IL  KG+ +P   + R+   +T    +  
Sbjct: 573 KSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMAC 632

Query: 559 LGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCR 618
            G R +  C  Y +  D  P +  + E +    + L    +V + DP R  VPDA+ KC+
Sbjct: 633 DGLRTI--CIAYRDFDDTEPSWDNENEIL----TELTCIAVVGIEDPVRPEVPDAIAKCK 686

Query: 619 TAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVING 678
            AGI V MVTGD+  TA+AIA   GI++ G + +             +  K+    + N 
Sbjct: 687 QAGITVRMVTGDNINTARAIATKCGILTPGDDFL------------CLEGKEFNRLIRN- 733

Query: 679 MQLKDMDPSELVEALRTHPEM-VFARTSPQQKLVIVESC--QRLGA---IVAVTGDGVND 732
               +    E  +  +  P++ V AR+SP  K  +V+      +G    +VAVTGDG ND
Sbjct: 734 ----EKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789

Query: 733 SPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLT 792
            PALKKAD+G AMGIAG+D AK A+D+IL DDNF SIV  V  GR ++D++ K + + LT
Sbjct: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849

Query: 793 KNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRP---RN 849
            N+  +        ++   PL  + +L++ L  D F S++LA E     ++  RP     
Sbjct: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909

Query: 850 PKRDRLVNEPLAAYSYFQI 868
           P   R + + +  ++++Q+
Sbjct: 910 PLISRTMMKNILGHAFYQL 928



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 65/263 (24%), Positives = 119/263 (45%), Gaps = 32/263 (12%)

Query: 51  EINDHQLSVAELEQKYQTSATKGLSASLAAELLLRD--GPNALRPPRGTPEYVKFARQLA 108
           +IN H   V  L  + +TS  +GLS + A     R   G N + PP+    +++   +  
Sbjct: 43  QINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVI-PPKKPKTFLELVWEAL 101

Query: 109 GGLQCLMWVAAAICLIAFAIQASEGD--------LTT--DDN---------LYLAIALIA 149
             +  ++   AAI  +  +     G+         TT  D+N           +  ++I 
Sbjct: 102 QDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVII 161

Query: 150 VVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDR 209
           VV+VT    + +E +   +    +    Q+ ++IR+G   Q+   ++VVGD+ ++K GD 
Sbjct: 162 VVLVTAFNDWSKEKQFRGLQCRIEQ--EQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDL 219

Query: 210 VPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLV 269
           +PAD  ++     K+D SSLTGES+   +S        L+   +    T  +EG+ + +V
Sbjct: 220 LPADGILIQGNDLKIDESSLTGESDHVKKS--------LDKDPMLLSGTHVMEGSGRMVV 271

Query: 270 VNTGDRTIIGRIASLASGVENEK 292
              G  +  G I +L    E+++
Sbjct: 272 TAVGVNSQTGIILTLLGVNEDDE 294


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
           sapiens]
          Length = 1205

 Score =  223 bits (567), Expect = 9e-58
 Identities = 173/559 (30%), Positives = 277/559 (49%), Gaps = 54/559 (9%)

Query: 328 FLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSD 387
           F++  +  + ++V  VPEGL   VT+ L+ + K++   N +V++L+A ET+G+ + ICSD
Sbjct: 406 FVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSD 465

Query: 388 KTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLC-NRAAFKS 446
           KTGTLT NRMTV   +               G  + Q       L +VL L  N  +  S
Sbjct: 466 KTGTLTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINS 512

Query: 447 GQDAVPVPKRIV------IGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQ 500
              +  +P          +G+ +E ALL F      +    R+  P+       + N  +
Sbjct: 513 AYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVR 572

Query: 501 LSIHTLEDPRDPRHLLVMKGAPERVLERCSSILI-KGQELPLDEQWREAF-QTAYLSLGG 558
            S+ T+    +    +  KGA E +L +C+ IL  KG+ +P   + R+   +T    +  
Sbjct: 573 KSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMAC 632

Query: 559 LGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCR 618
            G R +  C  Y +  D  P +  + E +    + L    +V + DP R  VPDA+ KC+
Sbjct: 633 DGLRTI--CIAYRDFDDTEPSWDNENEIL----TELTCIAVVGIEDPVRPEVPDAIAKCK 686

Query: 619 TAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVING 678
            AGI V MVTGD+  TA+AIA   GI++ G + +             +  K+    + N 
Sbjct: 687 QAGITVRMVTGDNINTARAIATKCGILTPGDDFL------------CLEGKEFNRLIRN- 733

Query: 679 MQLKDMDPSELVEALRTHPEM-VFARTSPQQKLVIVESC--QRLGA---IVAVTGDGVND 732
               +    E  +  +  P++ V AR+SP  K  +V+      +G    +VAVTGDG ND
Sbjct: 734 ----EKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789

Query: 733 SPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLT 792
            PALKKAD+G AMGIAG+D AK A+D+IL DDNF SIV  V  GR ++D++ K + + LT
Sbjct: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849

Query: 793 KNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRP---RN 849
            N+  +        ++   PL  + +L++ L  D F S++LA E     ++  RP     
Sbjct: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909

Query: 850 PKRDRLVNEPLAAYSYFQI 868
           P   R + + +  ++++Q+
Sbjct: 910 PLISRTMMKNILGHAFYQL 928



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 65/263 (24%), Positives = 119/263 (45%), Gaps = 32/263 (12%)

Query: 51  EINDHQLSVAELEQKYQTSATKGLSASLAAELLLRD--GPNALRPPRGTPEYVKFARQLA 108
           +IN H   V  L  + +TS  +GLS + A     R   G N + PP+    +++   +  
Sbjct: 43  QINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVI-PPKKPKTFLELVWEAL 101

Query: 109 GGLQCLMWVAAAICLIAFAIQASEGD--------LTT--DDN---------LYLAIALIA 149
             +  ++   AAI  +  +     G+         TT  D+N           +  ++I 
Sbjct: 102 QDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVII 161

Query: 150 VVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDR 209
           VV+VT    + +E +   +    +    Q+ ++IR+G   Q+   ++VVGD+ ++K GD 
Sbjct: 162 VVLVTAFNDWSKEKQFRGLQCRIEQ--EQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDL 219

Query: 210 VPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLV 269
           +PAD  ++     K+D SSLTGES+   +S        L+   +    T  +EG+ + +V
Sbjct: 220 LPADGILIQGNDLKIDESSLTGESDHVKKS--------LDKDPMLLSGTHVMEGSGRMVV 271

Query: 270 VNTGDRTIIGRIASLASGVENEK 292
              G  +  G I +L    E+++
Sbjct: 272 TAVGVNSQTGIILTLLGVNEDDE 294


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
           sapiens]
          Length = 1220

 Score =  221 bits (564), Expect = 2e-57
 Identities = 179/621 (28%), Positives = 303/621 (48%), Gaps = 73/621 (11%)

Query: 286 SGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCI--GYT------------FLRA 331
           S ++ + T +A++I     +++ + ++    +F++   +  G T            F++ 
Sbjct: 358 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKF 417

Query: 332 MVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGT 391
            +  + ++V  VPEGL   VT+ L+ + K++   N +V++L+A ET+G+ + ICSDKTGT
Sbjct: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 477

Query: 392 LTQNRMTVSHLWF-DNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFK--SGQ 448
           LT NRMTV   +  D H          + +  D        L   +++ +    K    +
Sbjct: 478 LTTNRMTVVQSYLGDTHYKEIPAPSALTPKILD-------LLVHAISINSAYTTKILPPE 530

Query: 449 DAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLED 508
               +P++  +G+ +E ALL F      +    R++ P+       + N  + S+ T+  
Sbjct: 531 KEGALPRQ--VGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIR 588

Query: 509 PRDPRHLLVMKGAPERVLERCSSILIKGQEL------PLDEQWREAFQTAYLSLGGLGER 562
             D    L  KGA E +L++C++IL    EL        D+  R+  +   ++  GL   
Sbjct: 589 MPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEP--MACDGLRTI 646

Query: 563 VLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGI 622
            + +       +D+  G   D +  N     L    +V + DP R  VP+A+ KC+ AGI
Sbjct: 647 CIAY-------RDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGI 699

Query: 623 RVIMVTGDHPITAKAIAASVGIISEGSETV----EDIAARLRVPVDQVNRKDARACVING 678
            V MVTGD+  TA+AIAA  GII  G + +    ++   R+R    ++ ++         
Sbjct: 700 TVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQE--------- 750

Query: 679 MQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE-----SCQRLGAIVAVTGDGVNDS 733
            +L  + P      LR     V AR+SP  K  +V+     +      +VAVTGDG ND 
Sbjct: 751 -RLDKVWPK-----LR-----VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDG 799

Query: 734 PALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTK 793
           PALKKAD+G AMGIAG+D AK A+D+IL DDNF SIV  V  GR ++D++ K + + LT 
Sbjct: 800 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTV 859

Query: 794 NIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRP---RNP 850
           N+  +        ++   PL  + +L++ L  D F S++LA E     ++  +P     P
Sbjct: 860 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKP 919

Query: 851 KRDRLVNEPLAAYSYFQIGAI 871
              R + + +  ++ +Q+  I
Sbjct: 920 LISRTMMKNILGHAVYQLAII 940



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 77/310 (24%), Positives = 137/310 (44%), Gaps = 44/310 (14%)

Query: 11  SVELGPGPGGDMAAKMSKKKKAGGGGGKRKE-----KLENMKKEMEINDHQLSVAELEQK 65
           S+E  P P      +     +AGG G    E     +L   +   +I +    V+ L ++
Sbjct: 8   SIEFHPKP-----QQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRR 62

Query: 66  YQTSATKGLSASLAAELLLRD--GPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICL 123
            +TS T+GL+ +       R   G N + PP+    +++   +    +  ++   AAI  
Sbjct: 63  LKTSPTEGLADNTNDLEKRRQIYGQNFI-PPKQPKTFLQLVWEALQDVTLIILEVAAIVS 121

Query: 124 IAFAIQASEGDLTTD-------------------DNLYLAIALIAVVVVTGCFGYYQEFK 164
           +  +  A  G+ +                     +   + +++I VV+VT    + +E +
Sbjct: 122 LGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQ 181

Query: 165 STNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKV 224
              + +  +    Q+ TVIR+G   Q+    LVVGD+ ++K GD +PAD  ++ A   K+
Sbjct: 182 FRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKI 239

Query: 225 DNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASL 284
           D SSLTGES+   +S +   + P+         T  +EG+ + +V   G  +  G I +L
Sbjct: 240 DESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 291

Query: 285 --ASGVENEK 292
             A G E EK
Sbjct: 292 LGAGGEEEEK 301


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
           sapiens]
          Length = 1173

 Score =  221 bits (564), Expect = 2e-57
 Identities = 179/621 (28%), Positives = 303/621 (48%), Gaps = 73/621 (11%)

Query: 286 SGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCI--GYT------------FLRA 331
           S ++ + T +A++I     +++ + ++    +F++   +  G T            F++ 
Sbjct: 358 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKF 417

Query: 332 MVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGT 391
            +  + ++V  VPEGL   VT+ L+ + K++   N +V++L+A ET+G+ + ICSDKTGT
Sbjct: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 477

Query: 392 LTQNRMTVSHLWF-DNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFK--SGQ 448
           LT NRMTV   +  D H          + +  D        L   +++ +    K    +
Sbjct: 478 LTTNRMTVVQSYLGDTHYKEIPAPSALTPKILD-------LLVHAISINSAYTTKILPPE 530

Query: 449 DAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLED 508
               +P++  +G+ +E ALL F      +    R++ P+       + N  + S+ T+  
Sbjct: 531 KEGALPRQ--VGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIR 588

Query: 509 PRDPRHLLVMKGAPERVLERCSSILIKGQEL------PLDEQWREAFQTAYLSLGGLGER 562
             D    L  KGA E +L++C++IL    EL        D+  R+  +   ++  GL   
Sbjct: 589 MPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEP--MACDGLRTI 646

Query: 563 VLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGI 622
            + +       +D+  G   D +  N     L    +V + DP R  VP+A+ KC+ AGI
Sbjct: 647 CIAY-------RDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGI 699

Query: 623 RVIMVTGDHPITAKAIAASVGIISEGSETV----EDIAARLRVPVDQVNRKDARACVING 678
            V MVTGD+  TA+AIAA  GII  G + +    ++   R+R    ++ ++         
Sbjct: 700 TVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQE--------- 750

Query: 679 MQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE-----SCQRLGAIVAVTGDGVNDS 733
            +L  + P      LR     V AR+SP  K  +V+     +      +VAVTGDG ND 
Sbjct: 751 -RLDKVWPK-----LR-----VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDG 799

Query: 734 PALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTK 793
           PALKKAD+G AMGIAG+D AK A+D+IL DDNF SIV  V  GR ++D++ K + + LT 
Sbjct: 800 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTV 859

Query: 794 NIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRP---RNP 850
           N+  +        ++   PL  + +L++ L  D F S++LA E     ++  +P     P
Sbjct: 860 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKP 919

Query: 851 KRDRLVNEPLAAYSYFQIGAI 871
              R + + +  ++ +Q+  I
Sbjct: 920 LISRTMMKNILGHAVYQLAII 940



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 77/310 (24%), Positives = 137/310 (44%), Gaps = 44/310 (14%)

Query: 11  SVELGPGPGGDMAAKMSKKKKAGGGGGKRKE-----KLENMKKEMEINDHQLSVAELEQK 65
           S+E  P P      +     +AGG G    E     +L   +   +I +    V+ L ++
Sbjct: 8   SIEFHPKP-----QQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRR 62

Query: 66  YQTSATKGLSASLAAELLLRD--GPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICL 123
            +TS T+GL+ +       R   G N + PP+    +++   +    +  ++   AAI  
Sbjct: 63  LKTSPTEGLADNTNDLEKRRQIYGQNFI-PPKQPKTFLQLVWEALQDVTLIILEVAAIVS 121

Query: 124 IAFAIQASEGDLTTD-------------------DNLYLAIALIAVVVVTGCFGYYQEFK 164
           +  +  A  G+ +                     +   + +++I VV+VT    + +E +
Sbjct: 122 LGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQ 181

Query: 165 STNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKV 224
              + +  +    Q+ TVIR+G   Q+    LVVGD+ ++K GD +PAD  ++ A   K+
Sbjct: 182 FRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKI 239

Query: 225 DNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASL 284
           D SSLTGES+   +S +   + P+         T  +EG+ + +V   G  +  G I +L
Sbjct: 240 DESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 291

Query: 285 --ASGVENEK 292
             A G E EK
Sbjct: 292 LGAGGEEEEK 301


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,608,018
Number of Sequences: 37866
Number of extensions: 1713319
Number of successful extensions: 4692
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4343
Number of HSP's gapped (non-prelim): 194
length of query: 1035
length of database: 18,247,518
effective HSP length: 112
effective length of query: 923
effective length of database: 14,006,526
effective search space: 12928023498
effective search space used: 12928023498
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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