BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] (1035 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 2072 0.0 gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 1338 0.0 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 1330 0.0 gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 1326 0.0 gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 1323 0.0 gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 1320 0.0 gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 1317 0.0 gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 1246 0.0 gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 373 e-103 gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 373 e-103 gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 373 e-103 gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 373 e-103 gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 373 e-103 gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 373 e-103 gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 373 e-103 gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 371 e-102 gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 371 e-102 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 356 7e-98 gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 356 7e-98 gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 356 7e-98 gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 356 7e-98 gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 356 7e-98 gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 356 7e-98 gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 344 3e-94 gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 331 2e-90 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 253 9e-67 gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 223 9e-58 gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 223 9e-58 gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 221 2e-57 gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 221 2e-57 >gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] Length = 1035 Score = 2072 bits (5368), Expect = 0.0 Identities = 1035/1035 (100%), Positives = 1035/1035 (100%) Query: 1 MGKAENYELYSVELGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVA 60 MGKAENYELYSVELGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVA Sbjct: 1 MGKAENYELYSVELGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVA 60 Query: 61 ELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAA 120 ELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAA Sbjct: 61 ELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAA 120 Query: 121 ICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQA 180 ICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQA Sbjct: 121 ICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQA 180 Query: 181 TVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSP 240 TVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSP Sbjct: 181 TVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSP 240 Query: 241 ECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIE 300 ECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIE Sbjct: 241 ECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIE 300 Query: 301 HFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAK 360 HFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAK Sbjct: 301 HFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAK 360 Query: 361 RLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQ 420 RLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQ Sbjct: 361 RLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQ 420 Query: 421 TFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMG 480 TFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMG Sbjct: 421 TFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMG 480 Query: 481 YRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELP 540 YRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELP Sbjct: 481 YRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELP 540 Query: 541 LDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLV 600 LDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLV Sbjct: 541 LDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLV 600 Query: 601 SMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLR 660 SMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLR Sbjct: 601 SMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLR 660 Query: 661 VPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLG 720 VPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLG Sbjct: 661 VPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLG 720 Query: 721 AIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIF 780 AIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIF Sbjct: 721 AIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIF 780 Query: 781 DNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAES 840 DNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAES Sbjct: 781 DNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAES 840 Query: 841 DIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQ 900 DIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQ Sbjct: 841 DIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQ 900 Query: 901 WEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGF 960 WEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGF Sbjct: 901 WEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGF 960 Query: 961 FRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLG 1020 FRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLG Sbjct: 961 FRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLG 1020 Query: 1021 VRCCPGSWWDQELYY 1035 VRCCPGSWWDQELYY Sbjct: 1021 VRCCPGSWWDQELYY 1035 >gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] Length = 1013 Score = 1338 bits (3463), Expect = 0.0 Identities = 656/1014 (64%), Positives = 801/1014 (78%), Gaps = 1/1014 (0%) Query: 22 MAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAE 81 M K K GK + L+++KKE+ + +H++SV E+ +KY T +GL+ S A E Sbjct: 1 MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE 60 Query: 82 LLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNL 141 +L RDGPNAL PP TPE+VKF RQL GG L+W+ A +C +A+ IQA D + DNL Sbjct: 61 ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNL 120 Query: 142 YLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDL 201 YL I L AVV++TGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K Q+NA+++VVGDL Sbjct: 121 YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL 180 Query: 202 VEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCL 261 VE+KGGDRVPAD+RI++A GCKVDNSSLTGESEPQTRSP+CTH++PLETRNI FFST C+ Sbjct: 181 VEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV 240 Query: 262 EGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVA 321 EGT +G+VV TGDRT++GRIA+LASG+E KTPIAIEIEHF+ +I G+A+ G +FFI++ Sbjct: 241 EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS 300 Query: 322 MCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGST 381 + +GYT+L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGST Sbjct: 301 LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST 360 Query: 382 SVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNR 441 S ICSDKTGTLTQNRMTV+H+WFDN IH ADTTEDQSG +FD+SS TW AL + LCNR Sbjct: 361 STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR 420 Query: 442 AAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQL 501 A FK GQD +PV KR V GDASE+ALLK EL+ G+ R+R KV EIPFNSTNK+QL Sbjct: 421 AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL 480 Query: 502 SIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGE 561 SIH EDP D R+LLVMKGAPER+L+RCS+IL++G+E PLDE+ +EAFQ AYL LGGLGE Sbjct: 481 SIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGE 540 Query: 562 RVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAG 621 RVLGFC YL E+ +P G+AFD + +NF + LCF GL+SMIDPPRA VPDAV KCR+AG Sbjct: 541 RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG 600 Query: 622 IRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQL 681 I+VIMVTGDHPITAKAIA VGIISEG+ETVEDIAARL +PV QVN +DA+ACVI+G L Sbjct: 601 IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL 660 Query: 682 KDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADI 741 KD ++ E L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDSPALKKADI Sbjct: 661 KDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI 720 Query: 742 GVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPY 801 GVAMGIAGSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT NIPE+TP+ Sbjct: 721 GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF 780 Query: 802 LIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLA 861 L++I ++PLPLG ITIL I+L TD+ P++SLAYE AESDIM +PRNP+ D+LVNE L Sbjct: 781 LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI 840 Query: 862 AYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQ 921 + +Y QIG IQ+ GF YF +A+ G+ P VG+R W+D + DL+DSYGQ+WT+ Q Sbjct: 841 SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ 900 Query: 922 RLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLC 981 R ++TC+T FF+SI V Q AD++I KTRR S FQQG +NKIL+ + + + FL Sbjct: 901 RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLS 959 Query: 982 YCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035 YCPGM P++ WW PY LIFVYDEIRKL +R PG W ++E YY Sbjct: 960 YCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 1330 bits (3441), Expect = 0.0 Identities = 664/1033 (64%), Positives = 808/1033 (78%), Gaps = 5/1033 (0%) Query: 8 ELYSVELGPGPGGDMAAKMSKKKKAGGGGG-----KRKEKLENMKKEMEINDHQLSVAEL 62 E+YSVEL K K+K G K+K E +KE+ ++DH+LS EL Sbjct: 7 EIYSVELSGTKDIVKTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNREL 66 Query: 63 EQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAIC 122 E+KY T GLS++ AAELL RDGPN+L PP+ TPE VKF +Q+ GG L+WV A +C Sbjct: 67 EEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLC 126 Query: 123 LIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATV 182 IA+ IQ S + +N+YL L VV++TG F YYQE KSTNI++SF ++PQQA V Sbjct: 127 WIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALV 186 Query: 183 IRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPEC 242 IRD +K I ++QLVVGD+VE+KGGD++PADIR+L++QGC+VDNSSLTGESEPQ RS E Sbjct: 187 IRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEF 246 Query: 243 THESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHF 302 THE+PLET+NI F+ST CLEGTV G+V+NTGDRTIIG IASLASGV NEKTPIAIEIEHF Sbjct: 247 THENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHF 306 Query: 303 VDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRL 362 V I+AG+A+ G FFI+A+ + Y L +++F + I+VA VPEGLLATVTV LSLTAKR+ Sbjct: 307 VHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRM 366 Query: 363 ASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTF 422 A KNC+VKNLEAVETLGSTS+ICSDKTGTLTQNRMTV+HLWFDN I ADT+ED S Q F Sbjct: 367 AKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVF 426 Query: 423 DQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYR 482 DQSS TW +L +++TLCNRA FK GQ+ VP+ K+ VIGDASETALLKFSE+ LG+ M R Sbjct: 427 DQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIR 486 Query: 483 DRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLD 542 R KV EIPFNSTNKFQLSIH ++DP R L+VMKGAPER+LE+CS+I+I G+E PLD Sbjct: 487 KRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLD 546 Query: 543 EQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSM 602 + + F TAY+ LGGLGERVLGFC LYL ++P Y+FD++AMNFP+S LCF GL+SM Sbjct: 547 KSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSM 606 Query: 603 IDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVP 662 IDPPR+TVPDAV KCR+AGI+VIMVTGDHPITAKAIA SVGIIS SETVEDIA RL + Sbjct: 607 IDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIA 666 Query: 663 VDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAI 722 V+QVN++DA+A V+ GM+LKDM +L E L + E+VFARTSPQQKL+IVE CQR A+ Sbjct: 667 VEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAV 726 Query: 723 VAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDN 782 VAVTGDGVNDSPALKKADIG+AMGIAGSDAAKNAADM+LLDDNFASIVTGVE+GRLIFDN Sbjct: 727 VAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDN 786 Query: 783 LKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDI 842 LKK+IAY+LTKNI EL P+LIYI V +PLP+G ITILFI+L TDI PS++LAYEKAESDI Sbjct: 787 LKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDI 846 Query: 843 MHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWE 902 M+ +PR+ +DRLVN+PLA YSY IG +Q+ F YFT AQEG+ P + LR +WE Sbjct: 847 MNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWE 906 Query: 903 DHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFR 962 ++ DL+DSYGQEWT QR Y ++T YT FF+ I V QIAD++IRKTRR S FQQG FR Sbjct: 907 KDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFR 966 Query: 963 NKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVR 1022 NK++ + I Q+ IG L Y G +F +R Q+W V +P+ ILI+VYDE+RKL +R Sbjct: 967 NKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIR 1026 Query: 1023 CCPGSWWDQELYY 1035 PGSWWD+ +YY Sbjct: 1027 LYPGSWWDKNMYY 1039 >gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] Length = 1023 Score = 1326 bits (3431), Expect = 0.0 Identities = 644/1024 (62%), Positives = 814/1024 (79%), Gaps = 3/1024 (0%) Query: 14 LGPGPGGDM--AAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSAT 71 +G G G D A +S++ G GK+ ++ +KKE+ ++DH+LS+ EL +KY T + Sbjct: 1 MGKGVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLS 60 Query: 72 KGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQAS 131 +GL+++ AAE+L RDGPNAL PP TPE++KF RQL GG L+W+ A +C +A++IQA+ Sbjct: 61 RGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAA 120 Query: 132 EGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQI 191 + +DNLYL + L AVV++TGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K I Sbjct: 121 TEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSI 180 Query: 192 NADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETR 251 NA+++VVGDLVE+KGGDR+PAD+RI++A GCKVDNSSLTGESEPQTRSP+ T+E+PLETR Sbjct: 181 NAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETR 240 Query: 252 NIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAI 311 NIAFFST C+EGT +G+VV TGDRT++GRIA+LASG+E +TPIA EIEHF+ II G+A+ Sbjct: 241 NIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAV 300 Query: 312 LFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKN 371 G +FFI+++ + YT+L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKN Sbjct: 301 FLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN 360 Query: 372 LEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRA 431 LEAVETLGSTS ICSDKTGTLTQNRMTV+H+WFDN IH ADTTE+QSG +FD++S TW A Sbjct: 361 LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLA 420 Query: 432 LCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEI 491 L R+ LCNRA F++ Q+ +P+ KR V GDASE+ALLK EL G+ R+R+ K+ EI Sbjct: 421 LSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEI 480 Query: 492 PFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQT 551 PFNSTNK+QLSIH + +P+HLLVMKGAPER+L+RCSSIL+ G+E PLDE+ ++AFQ Sbjct: 481 PFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN 540 Query: 552 AYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVP 611 AYL LGGLGERVLGFC L+L ++ +P G+ FD + +NFP LCF GL+SMIDPPRA VP Sbjct: 541 AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP 600 Query: 612 DAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDA 671 DAV KCR+AGI+VIMVTGDHPITAKAIA VGIISEG+ETVEDIAARL +PV QVN +DA Sbjct: 601 DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDA 660 Query: 672 RACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVN 731 +ACV++G LKDM +L + L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVN Sbjct: 661 KACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN 720 Query: 732 DSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTL 791 DSPALKKADIGVAMGIAGSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTL Sbjct: 721 DSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL 780 Query: 792 TKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851 T NIPE+TP+LI+I ++PLPLG +TIL I+L TD+ P++SLAYE+AESDIM +PRNPK Sbjct: 781 TSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPK 840 Query: 852 RDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQD 911 D+LVNE L + +Y QIG IQ+ GF YF +A+ G+ P+ +GLR W+D + D++D Sbjct: 841 TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVED 900 Query: 912 SYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIV 971 SYGQ+WT+ QR ++TC+T FF+SI V Q AD++I KTRR S FQQG +NKIL+ + Sbjct: 901 SYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQG-MKNKILIFGLF 959 Query: 972 FQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQ 1031 + + FL YCPGM P++ WW PY +LIFVYDE+RKL +R PG W ++ Sbjct: 960 EETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEK 1019 Query: 1032 ELYY 1035 E YY Sbjct: 1020 ETYY 1023 >gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens] Length = 1023 Score = 1323 bits (3425), Expect = 0.0 Identities = 640/1012 (63%), Positives = 809/1012 (79%), Gaps = 1/1012 (0%) Query: 24 AKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELL 83 A +S++ G GK+ ++ +KKE+ ++DH+LS+ EL +KY T ++GL+++ AAE+L Sbjct: 13 AAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEIL 72 Query: 84 LRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYL 143 RDGPNAL PP TPE++KF RQL GG L+W+ A +C +A++IQA+ + +DNLYL Sbjct: 73 ARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYL 132 Query: 144 AIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVE 203 + L AVV++TGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K INA+++VVGDLVE Sbjct: 133 GVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVE 192 Query: 204 MKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEG 263 +KGGDR+PAD+RI++A GCKVDNSSLTGESEPQTRSP+ T+E+PLETRNIAFFST C+EG Sbjct: 193 VKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEG 252 Query: 264 TVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMC 323 T +G+VV TGDRT++GRIA+LASG+E +TPIA EIEHF+ II G+A+ G +FFI+++ Sbjct: 253 TARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLI 312 Query: 324 IGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSV 383 + YT+L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGSTS Sbjct: 313 LEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTST 372 Query: 384 ICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAA 443 ICSDKTGTLTQNRMTV+H+WFDN IH ADTTE+QSG +FD++S TW AL R+ LCNRA Sbjct: 373 ICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAV 432 Query: 444 FKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSI 503 F++ Q+ +P+ KR V GDASE+ALLK EL G+ R+R+ K+ EIPFNSTNK+QLSI Sbjct: 433 FQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSI 492 Query: 504 HTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERV 563 H + +P+HLLVMKGAPER+L+RCSSIL+ G+E PLDE+ ++AFQ AYL LGGLGERV Sbjct: 493 HKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERV 552 Query: 564 LGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIR 623 LGFC L+L ++ +P G+ FD + +NFP LCF GL+SMIDPPRA VPDAV KCR+AGI+ Sbjct: 553 LGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIK 612 Query: 624 VIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKD 683 VIMVTGDHPITAKAIA VGIISEG+ETVEDIAARL +PV QVN +DA+ACV++G LKD Sbjct: 613 VIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKD 672 Query: 684 MDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGV 743 M +L + L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDSPALKKADIGV Sbjct: 673 MTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGV 732 Query: 744 AMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLI 803 AMGIAGSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT NIPE+TP+LI Sbjct: 733 AMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLI 792 Query: 804 YITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAY 863 +I ++PLPLG +TIL I+L TD+ P++SLAYE+AESDIM +PRNPK D+LVNE L + Sbjct: 793 FIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISM 852 Query: 864 SYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRL 923 +Y QIG IQ+ GF YF +A+ G+ P+ +GLR W+D + D++DSYGQ+WT+ QR Sbjct: 853 AYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRK 912 Query: 924 YQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYC 983 ++TC+T FF+SI V Q AD++I KTRR S FQQG +NKIL+ + + + FL YC Sbjct: 913 IVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYC 971 Query: 984 PGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035 PGM P++ WW PY +LIFVYDE+RKL +R PG W ++E YY Sbjct: 972 PGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023 >gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] Length = 1020 Score = 1320 bits (3417), Expect = 0.0 Identities = 640/1022 (62%), Positives = 809/1022 (79%), Gaps = 2/1022 (0%) Query: 14 LGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKG 73 +G G G + + + + GG +++++L+ +KKE+ ++DH+LS+ EL +KYQ +KG Sbjct: 1 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG 60 Query: 74 LSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEG 133 L+ A ++L RDGPNAL PP TPE+VKF RQL GG L+W+ A +C +A+ IQA+ Sbjct: 61 LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120 Query: 134 DLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINA 193 D ++DNLYL + L AVV+VTGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K QINA Sbjct: 121 DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180 Query: 194 DQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNI 253 +++VVGDLVE+KGGDRVPAD+RI+++ GCKVDNSSLTGESEPQTRSPE THE+PLETRNI Sbjct: 181 EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI 240 Query: 254 AFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILF 313 FFST C+EGT +G+V+ TGDRT++GRIA+LASG+E +TPIA+EIEHF+ +I G+A+ Sbjct: 241 CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL 300 Query: 314 GATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLE 373 G +FF++++ +GY++L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLE Sbjct: 301 GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE 360 Query: 374 AVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALC 433 AVETLGSTS ICSDKTGTLTQNRMTV+H+WFDN IH ADTTEDQSG TFD+ S TW AL Sbjct: 361 AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS 420 Query: 434 RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPF 493 R+ LCNRA FK+GQ+ + V KR GDASE+ALLK EL+ G+ RDR PKV EIPF Sbjct: 421 RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF 480 Query: 494 NSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAY 553 NSTNK+QLSIH ED H+LVMKGAPER+L+RCS+IL++G+E+PLD++ ++AFQ AY Sbjct: 481 NSTNKYQLSIHERED-SPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAY 539 Query: 554 LSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDA 613 + LGGLGERVLGFCQL L +P G+ FD + +NFP+ LCF GL+SMIDPPRA VPDA Sbjct: 540 MELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDA 599 Query: 614 VLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARA 673 V KCR+AGI+VIMVTGDHPITAKAIA VGIISEG+ETVEDIAARL +P+ QVN ++A+A Sbjct: 600 VGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKA 659 Query: 674 CVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDS 733 CV++G LKDM +L E L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDS Sbjct: 660 CVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDS 719 Query: 734 PALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTK 793 PALKKADIG+AMGI+GSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT Sbjct: 720 PALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTS 779 Query: 794 NIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRD 853 NIPE+TP+L++I ++PLPLG +TIL I+L TD+ P++SLAYE AESDIM +PRN + D Sbjct: 780 NIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTD 839 Query: 854 RLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSY 913 +LVNE L + +Y QIG IQ+ GF YF +A+ G+ P +G+R W+D + DL+DSY Sbjct: 840 KLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSY 899 Query: 914 GQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQ 973 GQEWT+ QR ++TC+T FF SI V Q AD++I KTRR S FQQG +NKIL+ ++ + Sbjct: 900 GQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLLEE 958 Query: 974 VCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQEL 1033 + FL YCPGM P++ WW PY +LIF+YDE+RKL +R PG W ++E Sbjct: 959 TALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKET 1018 Query: 1034 YY 1035 YY Sbjct: 1019 YY 1020 >gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens] Length = 992 Score = 1317 bits (3408), Expect = 0.0 Identities = 635/993 (63%), Positives = 800/993 (80%), Gaps = 1/993 (0%) Query: 43 LENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVK 102 ++ +KKE+ ++DH+LS+ EL +KY T ++GL+++ AAE+L RDGPNAL PP TPE++K Sbjct: 1 MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60 Query: 103 FARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQE 162 F RQL GG L+W+ A +C +A++IQA+ + +DNLYL + L AVV++TGCF YYQE Sbjct: 61 FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120 Query: 163 FKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGC 222 KS+ I+ SFKN+VPQQA VIR+G+K INA+++VVGDLVE+KGGDR+PAD+RI++A GC Sbjct: 121 AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180 Query: 223 KVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIA 282 KVDNSSLTGESEPQTRSP+ T+E+PLETRNIAFFST C+EGT +G+VV TGDRT++GRIA Sbjct: 181 KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240 Query: 283 SLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAY 342 +LASG+E +TPIA EIEHF+ II G+A+ G +FFI+++ + YT+L A++F + I+VA Sbjct: 241 TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300 Query: 343 VPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHL 402 VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGSTS ICSDKTGTLTQNRMTV+H+ Sbjct: 301 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360 Query: 403 WFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDA 462 WFDN IH ADTTE+QSG +FD++S TW AL R+ LCNRA F++ Q+ +P+ KR V GDA Sbjct: 361 WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420 Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522 SE+ALLK EL G+ R+R+ K+ EIPFNSTNK+QLSIH + +P+HLLVMKGAP Sbjct: 421 SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480 Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582 ER+L+RCSSIL+ G+E PLDE+ ++AFQ AYL LGGLGERVLGFC L+L ++ +P G+ F Sbjct: 481 ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540 Query: 583 DVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASV 642 D + +NFP LCF GL+SMIDPPRA VPDAV KCR+AGI+VIMVTGDHPITAKAIA V Sbjct: 541 DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600 Query: 643 GIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFA 702 GIISEG+ETVEDIAARL +PV QVN +DA+ACV++G LKDM +L + L+ H E+VFA Sbjct: 601 GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660 Query: 703 RTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILL 762 RTSPQQKL+IVE CQR GAIVAVTGDGVNDSPALKKADIGVAMGIAGSD +K AADMILL Sbjct: 661 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720 Query: 763 DDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIE 822 DDNFASIVTGVE+GRLIFDNLKKSIAYTLT NIPE+TP+LI+I ++PLPLG +TIL I+ Sbjct: 721 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780 Query: 823 LCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFT 882 L TD+ P++SLAYE+AESDIM +PRNPK D+LVNE L + +Y QIG IQ+ GF YF Sbjct: 781 LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840 Query: 883 AMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQI 942 +A+ G+ P+ +GLR W+D + D++DSYGQ+WT+ QR ++TC+T FF+SI V Q Sbjct: 841 ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900 Query: 943 ADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLV 1002 AD++I KTRR S FQQG +NKIL+ + + + FL YCPGM P++ WW Sbjct: 901 ADLVICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFC 959 Query: 1003 PLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035 PY +LIFVYDE+RKL +R PG W ++E YY Sbjct: 960 AFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992 >gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens] Length = 1029 Score = 1246 bits (3224), Expect = 0.0 Identities = 609/998 (61%), Positives = 770/998 (77%), Gaps = 3/998 (0%) Query: 38 KRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGT 97 K+K +E +KKE+ ++DH+L++ EL KY TKG S A E+L R GPN + PP T Sbjct: 35 KQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTT 94 Query: 98 PEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCF 157 PE+VKF +QL GG L+W A +C +A++IQ + T DNLYL+I L VV+VTGCF Sbjct: 95 PEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCF 154 Query: 158 GYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRIL 217 YYQE KS+ I+ SFKN+VPQQA VIR G+K QIN ++V+GDLVE+KGGDRVPAD+R++ Sbjct: 155 SYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLI 214 Query: 218 AAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTI 277 +AQGCKVDNSSLTGESEPQ+RSP+ THE+PLETRNI FFST C+EGT +G+V+ TGD T+ Sbjct: 215 SAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTV 274 Query: 278 IGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMA 337 +GRIASL SG+ +TPIA EIEHF+ +I +A+ G TFF +++ +GY +L A++F + Sbjct: 275 MGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIG 334 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGSTS ICSDKTGTLTQNRM Sbjct: 335 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 394 Query: 398 TVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRI 457 TV+H+WFD ++ ADTTE+Q+G+TF +SS+TW L R+ LCNRA FK+ Q+ +P+ KR Sbjct: 395 TVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRA 454 Query: 458 VIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLV 517 GDASE+ALLKF E + + R++ PKV EIPFNSTNK+Q+SIH ED H+L+ Sbjct: 455 TTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLRED-SSQTHVLM 513 Query: 518 MKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYP 577 MKGAPER+LE CS+ L+ GQE ++++ +EAFQ AYL LGGLGERVLGFC L L + Sbjct: 514 MKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNL-PSSFS 572 Query: 578 PGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKA 637 G+ F+ + +NFP LCF GL+SMIDPPRA VPDAV KCR+AGI+VIMVTGDHPITAKA Sbjct: 573 KGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKA 632 Query: 638 IAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHP 697 IA VGIISEG+ET E++AARL++P+ +V+ A+A V++G +LKD+ +L + L+ HP Sbjct: 633 IAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHP 692 Query: 698 EMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAA 757 E+VFARTSPQQKL+IVE CQRLGA+VAVTGDGVNDSPALKKADIG+AMGI+GSD +K AA Sbjct: 693 EIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAA 752 Query: 758 DMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCIT 817 DMILLDDNFASIVTGVE+GRLIFDNLKKSI YTLT NIPE+TP+L++I + +PLPLG IT Sbjct: 753 DMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTIT 812 Query: 818 ILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGF 877 IL I+L TD+ P++SLAYE AESDIM PRNPK D LVN L +Y QIG IQ+ AGF Sbjct: 813 ILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGF 872 Query: 878 TDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISI 937 YF +A+ G+ P+ +G+R WED +L DL+DSYGQ+WT+ QR ++TC T FF++I Sbjct: 873 FTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTI 932 Query: 938 EVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRF 997 V Q AD++I KTRR S FQQG RNK+L+ I+ + + FL Y PGM P++ Sbjct: 933 VVVQWADLIISKTRRNSLFQQG-MRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKI 991 Query: 998 QWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035 WWL +PY ILIFVYDEIRKL +R P W ++E YY Sbjct: 992 TWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029 >gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo sapiens] Length = 999 Score = 373 bits (958), Expect = e-103 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H L A++ + + +A GLS + R GPN L G + Q L + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA L++F + E T + ++ ++V G +QE + + I + K Sbjct: 65 LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ VIR K +I A +V GD+VE+ GD+VPAD+R++ + +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES T+ E + + +N+ F T G G+ V TG T +G+I S + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 VE E+TP+ +++ F ++ + +++ + G ++LR V++ +A Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440 +V ++ + SG T+ E + L + LCN Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484 +A + K +G+A+ETAL E T A+ +R Sbjct: 422 DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478 Query: 485 FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541 K + F+ K +S++ T P + +KGAPE V+ERCSS+ + + PL Sbjct: 479 MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537 Query: 542 DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596 RE A + G G L L L +D PP D+E + + L F Sbjct: 538 TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593 Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656 G V M+DPPR V + +C AGIRV+M+TGD+ TA AI +GI + ED+A Sbjct: 594 VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649 Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716 + G + D+ P + +A RT FAR P K IVE+ Sbjct: 650 GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691 Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK+AA+M+L DDNFASIV VE+G Sbjct: 692 QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750 Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836 R I+ N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L + Sbjct: 751 RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810 Query: 837 KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896 + DIM PR+P R+ L+ + + +F+ AI + G T A WF G Sbjct: 811 PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862 Query: 897 LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951 + + L+ +D+ G + + + +V ++IE+C + L + Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918 Query: 952 RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011 S + + N L++A+ + + + P +P IF P+ + W+V L + + Sbjct: 919 NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978 Query: 1012 VYDEIRK 1018 + DE K Sbjct: 979 LLDEALK 985 >gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 373 bits (958), Expect = e-103 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H L A++ + + +A GLS + R GPN L G + Q L + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA L++F + E T + ++ ++V G +QE + + I + K Sbjct: 65 LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ VIR K +I A +V GD+VE+ GD+VPAD+R++ + +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES T+ E + + +N+ F T G G+ V TG T +G+I S + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 VE E+TP+ +++ F ++ + +++ + G ++LR V++ +A Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440 +V ++ + SG T+ E + L + LCN Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484 +A + K +G+A+ETAL E T A+ +R Sbjct: 422 DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478 Query: 485 FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541 K + F+ K +S++ T P + +KGAPE V+ERCSS+ + + PL Sbjct: 479 MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537 Query: 542 DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596 RE A + G G L L L +D PP D+E + + L F Sbjct: 538 TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593 Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656 G V M+DPPR V + +C AGIRV+M+TGD+ TA AI +GI + ED+A Sbjct: 594 VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649 Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716 + G + D+ P + +A RT FAR P K IVE+ Sbjct: 650 GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691 Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK+AA+M+L DDNFASIV VE+G Sbjct: 692 QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750 Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836 R I+ N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L + Sbjct: 751 RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810 Query: 837 KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896 + DIM PR+P R+ L+ + + +F+ AI + G T A WF G Sbjct: 811 PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862 Query: 897 LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951 + + L+ +D+ G + + + +V ++IE+C + L + Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918 Query: 952 RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011 S + + N L++A+ + + + P +P IF P+ + W+V L + + Sbjct: 919 NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978 Query: 1012 VYDEIRK 1018 + DE K Sbjct: 979 LLDEALK 985 >gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo sapiens] Length = 998 Score = 373 bits (958), Expect = e-103 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H L A++ + + +A GLS + R GPN L G + Q L + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA L++F + E T + ++ ++V G +QE + + I + K Sbjct: 65 LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ VIR K +I A +V GD+VE+ GD+VPAD+R++ + +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES T+ E + + +N+ F T G G+ V TG T +G+I S + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 VE E+TP+ +++ F ++ + +++ + G ++LR V++ +A Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440 +V ++ + SG T+ E + L + LCN Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484 +A + K +G+A+ETAL E T A+ +R Sbjct: 422 DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478 Query: 485 FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541 K + F+ K +S++ T P + +KGAPE V+ERCSS+ + + PL Sbjct: 479 MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537 Query: 542 DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596 RE A + G G L L L +D PP D+E + + L F Sbjct: 538 TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593 Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656 G V M+DPPR V + +C AGIRV+M+TGD+ TA AI +GI + ED+A Sbjct: 594 VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649 Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716 + G + D+ P + +A RT FAR P K IVE+ Sbjct: 650 GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691 Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK+AA+M+L DDNFASIV VE+G Sbjct: 692 QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750 Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836 R I+ N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L + Sbjct: 751 RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810 Query: 837 KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896 + DIM PR+P R+ L+ + + +F+ AI + G T A WF G Sbjct: 811 PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862 Query: 897 LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951 + + L+ +D+ G + + + +V ++IE+C + L + Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918 Query: 952 RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011 S + + N L++A+ + + + P +P IF P+ + W+V L + + Sbjct: 919 NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978 Query: 1012 VYDEIRK 1018 + DE K Sbjct: 979 LLDEALK 985 >gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 373 bits (958), Expect = e-103 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H L A++ + + +A GLS + R GPN L G + Q L + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA L++F + E T + ++ ++V G +QE + + I + K Sbjct: 65 LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ VIR K +I A +V GD+VE+ GD+VPAD+R++ + +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES T+ E + + +N+ F T G G+ V TG T +G+I S + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 VE E+TP+ +++ F ++ + +++ + G ++LR V++ +A Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440 +V ++ + SG T+ E + L + LCN Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484 +A + K +G+A+ETAL E T A+ +R Sbjct: 422 DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478 Query: 485 FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541 K + F+ K +S++ T P + +KGAPE V+ERCSS+ + + PL Sbjct: 479 MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537 Query: 542 DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596 RE A + G G L L L +D PP D+E + + L F Sbjct: 538 TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593 Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656 G V M+DPPR V + +C AGIRV+M+TGD+ TA AI +GI + ED+A Sbjct: 594 VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649 Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716 + G + D+ P + +A RT FAR P K IVE+ Sbjct: 650 GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691 Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK+AA+M+L DDNFASIV VE+G Sbjct: 692 QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750 Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836 R I+ N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L + Sbjct: 751 RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810 Query: 837 KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896 + DIM PR+P R+ L+ + + +F+ AI + G T A WF G Sbjct: 811 PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862 Query: 897 LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951 + + L+ +D+ G + + + +V ++IE+C + L + Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918 Query: 952 RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011 S + + N L++A+ + + + P +P IF P+ + W+V L + + Sbjct: 919 NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978 Query: 1012 VYDEIRK 1018 + DE K Sbjct: 979 LLDEALK 985 >gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo sapiens] Length = 1043 Score = 373 bits (958), Expect = e-103 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H L A++ + + +A GLS + R GPN L G + Q L + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA L++F + E T + ++ ++V G +QE + + I + K Sbjct: 65 LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ VIR K +I A +V GD+VE+ GD+VPAD+R++ + +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES T+ E + + +N+ F T G G+ V TG T +G+I S + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 VE E+TP+ +++ F ++ + +++ + G ++LR V++ +A Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440 +V ++ + SG T+ E + L + LCN Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484 +A + K +G+A+ETAL E T A+ +R Sbjct: 422 DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478 Query: 485 FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541 K + F+ K +S++ T P + +KGAPE V+ERCSS+ + + PL Sbjct: 479 MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537 Query: 542 DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596 RE A + G G L L L +D PP D+E + + L F Sbjct: 538 TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593 Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656 G V M+DPPR V + +C AGIRV+M+TGD+ TA AI +GI + ED+A Sbjct: 594 VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649 Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716 + G + D+ P + +A RT FAR P K IVE+ Sbjct: 650 GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691 Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK+AA+M+L DDNFASIV VE+G Sbjct: 692 QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750 Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836 R I+ N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L + Sbjct: 751 RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810 Query: 837 KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896 + DIM PR+P R+ L+ + + +F+ AI + G T A WF G Sbjct: 811 PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862 Query: 897 LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951 + + L+ +D+ G + + + +V ++IE+C + L + Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918 Query: 952 RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011 S + + N L++A+ + + + P +P IF P+ + W+V L + + Sbjct: 919 NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978 Query: 1012 VYDEIRK 1018 + DE K Sbjct: 979 LLDEALK 985 >gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo sapiens] Length = 1044 Score = 373 bits (958), Expect = e-103 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H L A++ + + +A GLS + R GPN L G + Q L + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA L++F + E T + ++ ++V G +QE + + I + K Sbjct: 65 LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ VIR K +I A +V GD+VE+ GD+VPAD+R++ + +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES T+ E + + +N+ F T G G+ V TG T +G+I S + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 VE E+TP+ +++ F ++ + +++ + G ++LR V++ +A Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440 +V ++ + SG T+ E + L + LCN Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484 +A + K +G+A+ETAL E T A+ +R Sbjct: 422 DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478 Query: 485 FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541 K + F+ K +S++ T P + +KGAPE V+ERCSS+ + + PL Sbjct: 479 MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537 Query: 542 DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596 RE A + G G L L L +D PP D+E + + L F Sbjct: 538 TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593 Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656 G V M+DPPR V + +C AGIRV+M+TGD+ TA AI +GI + ED+A Sbjct: 594 VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649 Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716 + G + D+ P + +A RT FAR P K IVE+ Sbjct: 650 GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691 Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK+AA+M+L DDNFASIV VE+G Sbjct: 692 QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750 Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836 R I+ N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L + Sbjct: 751 RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810 Query: 837 KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896 + DIM PR+P R+ L+ + + +F+ AI + G T A WF G Sbjct: 811 PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862 Query: 897 LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951 + + L+ +D+ G + + + +V ++IE+C + L + Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918 Query: 952 RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011 S + + N L++A+ + + + P +P IF P+ + W+V L + + Sbjct: 919 NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978 Query: 1012 VYDEIRK 1018 + DE K Sbjct: 979 LLDEALK 985 >gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo sapiens] Length = 1052 Score = 373 bits (958), Expect = e-103 Identities = 307/1027 (29%), Positives = 487/1027 (47%), Gaps = 109/1027 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H L A++ + + +A GLS + R GPN L G + Q L + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA L++F + E T + ++ ++V G +QE + + I + K Sbjct: 65 LLLAA---LVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ VIR K +I A +V GD+VE+ GD+VPAD+R++ + +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES T+ E + + +N+ F T G G+ V TG T +G+I S + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 VE E+TP+ +++ F ++ + +++ + G ++LR V++ +A Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWRA--------------LCRVLTLCN 440 +V ++ + SG T+ E + L + LCN Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDR----------- 484 +A + K +G+A+ETAL E T A+ +R Sbjct: 422 DSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQL 478 Query: 485 FPKVCEIPFNSTNKFQLSIH---TLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL 541 K + F+ K +S++ T P + +KGAPE V+ERCSS+ + + PL Sbjct: 479 MRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPL 537 Query: 542 DEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPS-----SGLCF 596 RE A + G G L L L +D PP D+E + + L F Sbjct: 538 TPTSREQI-LAKIRDWGSGSDTLRC--LALATRDAPPRKE-DMELDDCSKFVQYETDLTF 593 Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656 G V M+DPPR V + +C AGIRV+M+TGD+ TA AI +GI + ED+A Sbjct: 594 VGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVA 649 Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716 + G + D+ P + +A RT FAR P K IVE+ Sbjct: 650 GK----------------AYTGREFDDLSPEQQRQACRT--ARCFARVEPAHKSRIVENL 691 Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK+AA+M+L DDNFASIV VE+G Sbjct: 692 QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEG 750 Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836 R I+ N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L + Sbjct: 751 RAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFN 810 Query: 837 KAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVG 896 + DIM PR+P R+ L+ + + +F+ AI + G T A WF G Sbjct: 811 PPDLDIMEKLPRSP-REALI----SGWLFFRYLAIGVYVGLA---TVAAATWWFVYDAEG 862 Query: 897 LRAQWED--HHLQDLQDS---YGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTR 951 + + L+ +D+ G + + + +V ++IE+C + L + Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSV-LVTIEMC---NALNSVSE 918 Query: 952 RLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIF 1011 S + + N L++A+ + + + P +P IF P+ + W+V L + + Sbjct: 919 NQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVI 978 Query: 1012 VYDEIRK 1018 + DE K Sbjct: 979 LLDEALK 985 >gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo sapiens] Length = 997 Score = 371 bits (953), Expect = e-102 Identities = 304/1034 (29%), Positives = 482/1034 (46%), Gaps = 112/1034 (10%) Query: 53 NDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQ 112 N H +V E+ + + + GLS +L R G N L G Q L Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLV 62 Query: 113 CLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASF 172 ++ +AA I + + E +T ++ ++ ++V G +QE + N I + Sbjct: 63 RILLLAACISFVLAWFEEGEETITAFVEPFV---ILLILVANAIVGVWQERNAENAIEAL 119 Query: 173 KNLVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSS 228 K P+ V R K +I A +V GD+VE+ GD+VPADIR+ + + +VD S Sbjct: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179 Query: 229 LTGESEPQTRSPECTHESPL--------ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGR 280 LTGES + H P+ + +N+ F T G G+VV TG T IG+ Sbjct: 180 LTGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGK 234 Query: 281 IASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVF 334 I E E+TP+ +++ F + ++ + L +I+ + G +++R ++ Sbjct: 235 IRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIY 294 Query: 335 F----MAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTG 390 + +A+ VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTG Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTG 354 Query: 391 TLTQNRMTVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALC 433 TLT N+M+V ++ + + + ++ +G T+ E + L Sbjct: 355 TLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414 Query: 434 RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETAL-------------LK-FSELTLGNAM 479 + LCN +A + K +G+A+ETAL LK S++ NA Sbjct: 415 TICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANAC 471 Query: 480 G--YRDRFPKVCEIPFNSTNKFQLSIHTLEDP-RDPRHLLVMKGAPERVLERCSSILIKG 536 + K + F+ K T P R + +KGAPE V++RC+ I + Sbjct: 472 NSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531 Query: 537 QELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNF--PSSGL 594 ++P+ ++ + G G L L ++ ++ NF + L Sbjct: 532 TKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNL 590 Query: 595 CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654 F G V M+DPPR V +V CR AGIRVIM+TGD+ TA AI +GI + ED Sbjct: 591 TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----ED 646 Query: 655 IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714 + ++ G + +++PS +A FAR P K IVE Sbjct: 647 VTSK----------------AFTGREFDELNPSAQRDACLN--ARCFARVEPSHKSKIVE 688 Query: 715 SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK A++M+L DDNF++IV VE Sbjct: 689 FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747 Query: 775 QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834 +GR I++N+K+ I Y ++ N+ E+ + + P L + +L++ L TD P+ +L Sbjct: 748 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807 Query: 835 YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893 + + DIM+ PRNPK EPL + + +F+ AI + G T A WF Sbjct: 808 FNPPDLDIMNKPPRNPK------EPLISGWLFFRYLAIGCYVGAA---TVGAAAWWFIAA 858 Query: 894 CVGLRAQWE--DHHLQ---DLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIR 948 G R + H LQ D D G + + Y +V ++IE+C + L Sbjct: 859 DGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSV-LVTIEMCNALNSL-- 915 Query: 949 KTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGI 1008 + S + + N LV +I + + + Y +P IF P+ WL+ L + Sbjct: 916 -SENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974 Query: 1009 LIFVYDEIRKLGVR 1022 + + DE K R Sbjct: 975 PVILMDETLKFVAR 988 >gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo sapiens] Length = 1042 Score = 371 bits (953), Expect = e-102 Identities = 304/1034 (29%), Positives = 482/1034 (46%), Gaps = 112/1034 (10%) Query: 53 NDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQ 112 N H +V E+ + + + GLS +L R G N L G Q L Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLV 62 Query: 113 CLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASF 172 ++ +AA I + + E +T ++ ++ ++V G +QE + N I + Sbjct: 63 RILLLAACISFVLAWFEEGEETITAFVEPFV---ILLILVANAIVGVWQERNAENAIEAL 119 Query: 173 KNLVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSS 228 K P+ V R K +I A +V GD+VE+ GD+VPADIR+ + + +VD S Sbjct: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179 Query: 229 LTGESEPQTRSPECTHESPL--------ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGR 280 LTGES + H P+ + +N+ F T G G+VV TG T IG+ Sbjct: 180 LTGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGK 234 Query: 281 IASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVF 334 I E E+TP+ +++ F + ++ + L +I+ + G +++R ++ Sbjct: 235 IRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIY 294 Query: 335 F----MAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTG 390 + +A+ VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTG Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTG 354 Query: 391 TLTQNRMTVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALC 433 TLT N+M+V ++ + + + ++ +G T+ E + L Sbjct: 355 TLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414 Query: 434 RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETAL-------------LK-FSELTLGNAM 479 + LCN +A + K +G+A+ETAL LK S++ NA Sbjct: 415 TICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANAC 471 Query: 480 G--YRDRFPKVCEIPFNSTNKFQLSIHTLEDP-RDPRHLLVMKGAPERVLERCSSILIKG 536 + K + F+ K T P R + +KGAPE V++RC+ I + Sbjct: 472 NSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531 Query: 537 QELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNF--PSSGL 594 ++P+ ++ + G G L L ++ ++ NF + L Sbjct: 532 TKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNL 590 Query: 595 CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654 F G V M+DPPR V +V CR AGIRVIM+TGD+ TA AI +GI + ED Sbjct: 591 TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----ED 646 Query: 655 IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714 + ++ G + +++PS +A FAR P K IVE Sbjct: 647 VTSK----------------AFTGREFDELNPSAQRDACLN--ARCFARVEPSHKSKIVE 688 Query: 715 SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK A++M+L DDNF++IV VE Sbjct: 689 FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747 Query: 775 QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834 +GR I++N+K+ I Y ++ N+ E+ + + P L + +L++ L TD P+ +L Sbjct: 748 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807 Query: 835 YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893 + + DIM+ PRNPK EPL + + +F+ AI + G T A WF Sbjct: 808 FNPPDLDIMNKPPRNPK------EPLISGWLFFRYLAIGCYVGAA---TVGAAAWWFIAA 858 Query: 894 CVGLRAQWE--DHHLQ---DLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIR 948 G R + H LQ D D G + + Y +V ++IE+C + L Sbjct: 859 DGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSV-LVTIEMCNALNSL-- 915 Query: 949 KTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGI 1008 + S + + N LV +I + + + Y +P IF P+ WL+ L + Sbjct: 916 -SENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974 Query: 1009 LIFVYDEIRKLGVR 1022 + + DE K R Sbjct: 975 PVILMDETLKFVAR 988 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 356 bits (913), Expect = 7e-98 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%) Query: 56 QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115 +L V+E+ Q GL+ + G N P + K+ Q L L+ Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175 +A I ++ DD + + +A++ VV V + QE++S + L Sbjct: 88 LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134 Query: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235 VP + +R+G A LV GD V + GDRVPAD+R+ A +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291 ++ P T+ NIAF T+ G +G+V+ TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351 KTP+ ++ ++ + +V +G L +++ VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411 TV L+L R+ K +VK L VETLG +VICSDKTGTLT+N MTV+H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462 T +Q G+ A+ R++ +CN A ++ ++G Sbjct: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425 Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522 +E AL+ + + +G G + + + E PF+S K+ +D + MKGA Sbjct: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483 Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582 E+V++ C++ KGQ L L +Q R+ +Q +G G RVL Sbjct: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528 Query: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641 + P G L F GLV +IDPPR V +AV +G+ + M+TGD TA AIA+ Sbjct: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583 Query: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700 +G+ S+ S++V +G ++ MD +L + + P++ V Sbjct: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616 Query: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760 F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG G+D K AADMI Sbjct: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676 Query: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820 L+DD+F +I++ +E+G+ I++N+K + + L+ +I LT + ++ P PL + IL+ Sbjct: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736 Query: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851 I + D P+ SL E + D++ PRN K Sbjct: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767 >gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens] Length = 949 Score = 356 bits (913), Expect = 7e-98 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%) Query: 56 QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115 +L V+E+ Q GL+ + G N P + K+ Q L L+ Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175 +A I ++ DD + + +A++ VV V + QE++S + L Sbjct: 88 LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134 Query: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235 VP + +R+G A LV GD V + GDRVPAD+R+ A +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291 ++ P T+ NIAF T+ G +G+V+ TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351 KTP+ ++ ++ + +V +G L +++ VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411 TV L+L R+ K +VK L VETLG +VICSDKTGTLT+N MTV+H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462 T +Q G+ A+ R++ +CN A ++ ++G Sbjct: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425 Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522 +E AL+ + + +G G + + + E PF+S K+ +D + MKGA Sbjct: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483 Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582 E+V++ C++ KGQ L L +Q R+ +Q +G G RVL Sbjct: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528 Query: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641 + P G L F GLV +IDPPR V +AV +G+ + M+TGD TA AIA+ Sbjct: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583 Query: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700 +G+ S+ S++V +G ++ MD +L + + P++ V Sbjct: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616 Query: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760 F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG G+D K AADMI Sbjct: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676 Query: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820 L+DD+F +I++ +E+G+ I++N+K + + L+ +I LT + ++ P PL + IL+ Sbjct: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736 Query: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851 I + D P+ SL E + D++ PRN K Sbjct: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767 >gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens] Length = 888 Score = 356 bits (913), Expect = 7e-98 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%) Query: 56 QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115 +L V+E+ Q GL+ + G N P + K+ Q L L+ Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175 +A I ++ DD + + +A++ VV V + QE++S + L Sbjct: 88 LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134 Query: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235 VP + +R+G A LV GD V + GDRVPAD+R+ A +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291 ++ P T+ NIAF T+ G +G+V+ TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351 KTP+ ++ ++ + +V +G L +++ VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411 TV L+L R+ K +VK L VETLG +VICSDKTGTLT+N MTV+H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462 T +Q G+ A+ R++ +CN A ++ ++G Sbjct: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425 Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522 +E AL+ + + +G G + + + E PF+S K+ +D + MKGA Sbjct: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483 Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582 E+V++ C++ KGQ L L +Q R+ +Q +G G RVL Sbjct: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528 Query: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641 + P G L F GLV +IDPPR V +AV +G+ + M+TGD TA AIA+ Sbjct: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583 Query: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700 +G+ S+ S++V +G ++ MD +L + + P++ V Sbjct: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616 Query: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760 F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG G+D K AADMI Sbjct: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676 Query: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820 L+DD+F +I++ +E+G+ I++N+K + + L+ +I LT + ++ P PL + IL+ Sbjct: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736 Query: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851 I + D P+ SL E + D++ PRN K Sbjct: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767 >gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens] Length = 919 Score = 356 bits (913), Expect = 7e-98 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%) Query: 56 QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115 +L V+E+ Q GL+ + G N P + K+ Q L L+ Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175 +A I ++ DD + + +A++ VV V + QE++S + L Sbjct: 88 LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134 Query: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235 VP + +R+G A LV GD V + GDRVPAD+R+ A +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291 ++ P T+ NIAF T+ G +G+V+ TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351 KTP+ ++ ++ + +V +G L +++ VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411 TV L+L R+ K +VK L VETLG +VICSDKTGTLT+N MTV+H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462 T +Q G+ A+ R++ +CN A ++ ++G Sbjct: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425 Query: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522 +E AL+ + + +G G + + + E PF+S K+ +D + MKGA Sbjct: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483 Query: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582 E+V++ C++ KGQ L L +Q R+ +Q +G G RVL Sbjct: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528 Query: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641 + P G L F GLV +IDPPR V +AV +G+ + M+TGD TA AIA+ Sbjct: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583 Query: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700 +G+ S+ S++V +G ++ MD +L + + P++ V Sbjct: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616 Query: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760 F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG G+D K AADMI Sbjct: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676 Query: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820 L+DD+F +I++ +E+G+ I++N+K + + L+ +I LT + ++ P PL + IL+ Sbjct: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736 Query: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851 I + D P+ SL E + D++ PRN K Sbjct: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767 >gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo sapiens] Length = 994 Score = 356 bits (913), Expect = 7e-98 Identities = 303/1033 (29%), Positives = 476/1033 (46%), Gaps = 113/1033 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H + E + S T GL+ L + G N L G + Q L + Sbjct: 5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA I + + E +T ++ ++ +++ G +QE + N I + K Sbjct: 65 LLLAACISFVLAWFEEGEETITAFVEPFV---ILLILIANAIVGVWQERNAENAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ V R K +I A +V GD+VE+ GD+VPADIRILA + +VD S LT Sbjct: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES + E + + +N+ F T G G+V TG T IG+I + Sbjct: 182 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 E +KTP+ +++ F + ++ + L +++ + G ++ R +++ +A Sbjct: 242 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCN 440 +V ++ + + ++ +G T+ E + L + LCN Sbjct: 362 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDRFPKVCEIPFNS 495 ++ + K +G+A+ETAL E T ++ +R C Sbjct: 422 DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVER-ANACNSVIRQ 477 Query: 496 TNKFQLSIHTLEDPRDPRHLLV-----------------MKGAPERVLERCSSILIKGQE 538 K + TLE RD + + V +KGAPE V++RC+ + + Sbjct: 478 LMKKEF---TLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTR 534 Query: 539 LPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPG---YAFDVEAMNFP-SSGL 594 +PL +E A + G G L L L +D PP D A + L Sbjct: 535 VPLTGPVKEKIM-AVIKEWGTGRDTLRC--LALATRDTPPKREEMVLDDSARFLEYETDL 591 Query: 595 CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654 F G+V M+DPPR V ++ CR AGIRVIM+TGD+ TA AI +GI E E+ Sbjct: 592 TFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGEN----EE 647 Query: 655 IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714 +A R G + D+ +E EA R FAR P K IVE Sbjct: 648 VADR----------------AYTGREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVE 689 Query: 715 SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK A++M+L DDNF++IV VE Sbjct: 690 YLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 748 Query: 775 QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834 +GR I++N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L Sbjct: 749 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 835 YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893 + + DIM PR+PK EPL + + +F+ AI + G T A WF Sbjct: 809 FNPPDLDIMDRPPRSPK------EPLISGWLFFRYMAIGGYVGAA---TVGAAAWWFLYA 859 Query: 894 CVGLRAQWED--HHLQDLQDSYGQEWTFGQ--RLYQQYTCYTVFFISIEVCQIADVLIRK 949 G + H +Q +D+ E + + T ++IE+C + L Sbjct: 860 EDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSL--- 916 Query: 950 TRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGIL 1009 + S + + N L+ +I + + + Y +P IF + WL+ L + Sbjct: 917 SENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLP 976 Query: 1010 IFVYDEIRKLGVR 1022 + DEI K R Sbjct: 977 VIGLDEILKFVAR 989 >gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo sapiens] Length = 1001 Score = 356 bits (913), Expect = 7e-98 Identities = 303/1033 (29%), Positives = 476/1033 (46%), Gaps = 113/1033 (10%) Query: 55 HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114 H + E + S T GL+ L + G N L G + Q L + Sbjct: 5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64 Query: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174 + +AA I + + E +T ++ ++ +++ G +QE + N I + K Sbjct: 65 LLLAACISFVLAWFEEGEETITAFVEPFV---ILLILIANAIVGVWQERNAENAIEALKE 121 Query: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230 P+ V R K +I A +V GD+VE+ GD+VPADIRILA + +VD S LT Sbjct: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181 Query: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287 GES + E + + +N+ F T G G+V TG T IG+I + Sbjct: 182 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241 Query: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337 E +KTP+ +++ F + ++ + L +++ + G ++ R +++ +A Sbjct: 242 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301 Query: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397 + VA +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCN 440 +V ++ + + ++ +G T+ E + L + LCN Sbjct: 362 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421 Query: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDRFPKVCEIPFNS 495 ++ + K +G+A+ETAL E T ++ +R C Sbjct: 422 DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVER-ANACNSVIRQ 477 Query: 496 TNKFQLSIHTLEDPRDPRHLLV-----------------MKGAPERVLERCSSILIKGQE 538 K + TLE RD + + V +KGAPE V++RC+ + + Sbjct: 478 LMKKEF---TLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTR 534 Query: 539 LPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPG---YAFDVEAMNFP-SSGL 594 +PL +E A + G G L L L +D PP D A + L Sbjct: 535 VPLTGPVKEKIM-AVIKEWGTGRDTLRC--LALATRDTPPKREEMVLDDSARFLEYETDL 591 Query: 595 CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654 F G+V M+DPPR V ++ CR AGIRVIM+TGD+ TA AI +GI E E+ Sbjct: 592 TFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGEN----EE 647 Query: 655 IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714 +A R G + D+ +E EA R FAR P K IVE Sbjct: 648 VADR----------------AYTGREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVE 689 Query: 715 SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774 Q I A+TGDGVND+PALKKA+IG+AMG +G+ AK A++M+L DDNF++IV VE Sbjct: 690 YLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 748 Query: 775 QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834 +GR I++N+K+ I Y ++ N+ E+ + + +P L + +L++ L TD P+ +L Sbjct: 749 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 835 YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893 + + DIM PR+PK EPL + + +F+ AI + G T A WF Sbjct: 809 FNPPDLDIMDRPPRSPK------EPLISGWLFFRYMAIGGYVGAA---TVGAAAWWFLYA 859 Query: 894 CVGLRAQWED--HHLQDLQDSYGQEWTFGQ--RLYQQYTCYTVFFISIEVCQIADVLIRK 949 G + H +Q +D+ E + + T ++IE+C + L Sbjct: 860 EDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSL--- 916 Query: 950 TRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGIL 1009 + S + + N L+ +I + + + Y +P IF + WL+ L + Sbjct: 917 SENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLP 976 Query: 1010 IFVYDEIRKLGVR 1022 + DEI K R Sbjct: 977 VIGLDEILKFVAR 989 >gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo sapiens] Length = 1015 Score = 344 bits (882), Expect = 3e-94 Identities = 290/1024 (28%), Positives = 468/1024 (45%), Gaps = 119/1024 (11%) Query: 53 NDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQ 112 N H +V E+ + + + GLS +L R G N L G Q L Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLV 62 Query: 113 CLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASF 172 ++ +AA I + + E +T ++ ++ ++V G +QE + N I + Sbjct: 63 RILLLAACISFVLAWFEEGEETITAFVEPFV---ILLILVANAIVGVWQERNAENAIEAL 119 Query: 173 KNLVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLT 230 K P+ V R K +I A +V GD+VE+ G ++ S+ Sbjct: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVI 161 Query: 231 GESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVEN 290 ++P P ++ + +N+ F T G G+VV TG T IG+I E Sbjct: 162 KHTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ 217 Query: 291 EKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MAIVV 340 E+TP+ +++ F + ++ + L +I+ + G +++R +++ +A+ V Sbjct: 218 ERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 277 Query: 341 AYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVS 400 A +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M+V Sbjct: 278 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 337 Query: 401 HLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCNRAA 443 ++ + + + ++ +G T+ E + L + LCN +A Sbjct: 338 RMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397 Query: 444 FKSGQDAVPVPKRIVIGDASETAL-------------LK-FSELTLGNAMG--YRDRFPK 487 + K +G+A+ETAL LK S++ NA + K Sbjct: 398 LDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 454 Query: 488 VCEIPFNSTNKFQLSIHTLEDP-RDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWR 546 + F+ K T P R + +KGAPE V++RC+ I + ++P+ + Sbjct: 455 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 514 Query: 547 EAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNF--PSSGLCFAGLVSMID 604 + + G G L L ++ ++ NF + L F G V M+D Sbjct: 515 QKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 573 Query: 605 PPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVD 664 PPR V +V CR AGIRVIM+TGD+ TA AI +GI + ED+ ++ Sbjct: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTSK------ 623 Query: 665 QVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVA 724 G + +++PS +A FAR P K IVE Q I A Sbjct: 624 ----------AFTGREFDELNPSAQRDACLN--ARCFARVEPSHKSKIVEFLQSFDEITA 671 Query: 725 VTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLK 784 +TGDGVND+PALKKA+IG+AMG +G+ AK A++M+L DDNF++IV VE+GR I++N+K Sbjct: 672 MTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK 730 Query: 785 KSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMH 844 + I Y ++ N+ E+ + + P L + +L++ L TD P+ +L + + DIM+ Sbjct: 731 QFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMN 790 Query: 845 LRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWE- 902 PRNPK EPL + + +F+ AI + G T A WF G R + Sbjct: 791 KPPRNPK------EPLISGWLFFRYLAIGCYVGAA---TVGAAAWWFIAADGGPRVSFYQ 841 Query: 903 -DHHLQ---DLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQ 958 H LQ D D G + + Y +V ++IE+C + L + S + Sbjct: 842 LSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSV-LVTIEMCNALNSL---SENQSLLRM 897 Query: 959 GFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRK 1018 + N LV +I + + + Y +P IF P+ WL+ L + + + DE K Sbjct: 898 PPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLK 957 Query: 1019 LGVR 1022 R Sbjct: 958 FVAR 961 >gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo sapiens] Length = 946 Score = 331 bits (848), Expect = 2e-90 Identities = 269/864 (31%), Positives = 405/864 (46%), Gaps = 101/864 (11%) Query: 29 KKKAGGGGGKRKEKLENMKKEMEINDH-QLSVAELEQKYQTSATK--------------- 72 KK GGG++ + LE ++E I++ +L E E+K K Sbjct: 11 KKLGFSGGGRQYQALEKDEEEALIDEQSELKAIEKEKKVTALPPKEACKCQKEDLARAFC 70 Query: 73 -----GLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFA 127 GLS + L G N P + K+ Q L L+ +A + + Sbjct: 71 VDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSALVSV---- 126 Query: 128 IQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGD 187 LT + ++IA +VVVT F QE++S + +VP + +R+G Sbjct: 127 -------LTKEYEDAVSIATAVLVVVTVAF--IQEYRSEKSLEELTKMVPPECNCLREGK 177 Query: 188 KFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP--QTRSPECTHE 245 + A +LV GD+V + GDR+PADIR+ VD SS TGE+EP +T SP Sbjct: 178 LQHLLARELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGG 237 Query: 246 SPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDI 305 NI F T+ G QG+V+ TG+ + G + + E KTP+ + +D Sbjct: 238 DLTTLSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPL----QKSMDR 293 Query: 306 IAGLAILFGATFFIVAMCIGYT----FLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKR 361 + LF + M IG++ L +++ VA +PEGL V V L L R Sbjct: 294 LGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLR 353 Query: 362 LASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQ- 420 +A K +VK L VETLG SV+CSDKTGTLT N MTV+ L + + + GQ Sbjct: 354 MAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQG 413 Query: 421 --TFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFS-ELTLGN 477 S E + V A +AV + K V+G +E AL+ + ++ L + Sbjct: 414 TVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAV-IRKNAVMGQPTEGALMALAMKMDLSD 472 Query: 478 AMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQ 537 ++ + + EIPF+S K+ +++ D + MKGA E V+ C+ G Sbjct: 473 I---KNSYIRKKEIPFSSEQKW-MAVKCSLKTEDQEDIYFMKGALEEVIRYCTMYNNGGI 528 Query: 538 ELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSG-LCF 596 LPL Q R +G LG RVL + P G L F Sbjct: 529 PLPLTPQQRSFCLQEEKRMGSLGLRVLALA--------------------SGPELGRLTF 568 Query: 597 AGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIA 656 GLV +IDPPR V +AV +G+ V M+TGD TA AI ++G+ + Sbjct: 569 LGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLCN---------- 618 Query: 657 ARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC 716 + ++G ++ ++ EL + R VF RTSP+ KL I+++ Sbjct: 619 --------------GKLQAMSGEEVDSVEKGELAD--RVGKVSVFFRTSPKHKLKIIKAL 662 Query: 717 QRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQG 776 Q GAIVA+TGDGVND+ ALK ADIG+AMG G+D +K AA+MIL+DD+F++I+ VE+G Sbjct: 663 QESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNAVEEG 722 Query: 777 RLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYE 836 + IF N+K + + L+ +I L+ + ++P PL + IL+I + D P+ SL E Sbjct: 723 KGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLGVE 782 Query: 837 KAESDIMHLRPRNPKRDRLVNEPL 860 + D PR+ RD +++ L Sbjct: 783 PVDKDAFRQPPRS-VRDTILSRAL 805 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 253 bits (645), Expect = 9e-67 Identities = 251/958 (26%), Positives = 421/958 (43%), Gaps = 163/958 (17%) Query: 143 LAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLV 202 + +++I VV+VT + +E + + + + Q+ TV+R G QI ++VVGD+ Sbjct: 157 ILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVVRAGQVVQIPVAEIVVGDIA 214 Query: 203 EMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLE 262 ++K GD +PAD + K+D SSLTGES+ +S + + P+ T +E Sbjct: 215 QVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-----LLSGTHVME 266 Query: 263 GTVQGLVVNTGDRTIIGRIASL--ASGVENEK---------------------------- 292 G+ + LV G + G I +L A G E EK Sbjct: 267 GSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDAD 326 Query: 293 -------------------TPIAIEIEHFVDIIAGLAILFGATFFIV------------- 320 T +A++I +++ + ++ +F V Sbjct: 327 DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPE 386 Query: 321 --AMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETL 378 + + Y F++ + + ++V VPEGL VT+ L+ + K++ N +V++L+A ET+ Sbjct: 387 CTPVYVQY-FVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETM 445 Query: 379 GSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTL 438 G+ + ICSDKTGTLT NRMTV + + +H + + S T +T L + + Sbjct: 446 GNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSSINT-----KTMELLINAIAI 499 Query: 439 CNRAAFK--SGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNST 496 + K + +P++ +G+ +E LL F + R + P+ + Sbjct: 500 NSAYTTKILPPEKEGALPRQ--VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTF 557 Query: 497 NKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPL------DEQWREAFQ 550 N + S+ T+ D + KGA E VL++C IL E + DE ++ + Sbjct: 558 NSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE 617 Query: 551 TAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATV 610 ++ GL C Y +D+P D + N + L +V + DP R V Sbjct: 618 P--MACDGLRT----ICVAY---RDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEV 668 Query: 611 PDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETV----EDIAARLRVPVDQV 666 P+A+ KC+ AGI V MVTGD+ TA+AIA GII G + + ++ R+R Sbjct: 669 PEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIR------ 722 Query: 667 NRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESC-----QRLGA 721 N K +++ ++ LR V AR+SP K +V+ Sbjct: 723 NEKG---------EIEQERIDKIWPKLR-----VLARSSPTDKHTLVKGIIDSTHTEQRQ 768 Query: 722 IVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFD 781 +VAVTGDG ND PALKKAD+G AMGIAG+D AK A+D+IL DDNF+SIV V GR ++D Sbjct: 769 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYD 828 Query: 782 NLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESD 841 ++ K + + LT N+ + ++ PL + +L++ L D F S++LA E Sbjct: 829 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTET 888 Query: 842 IMHLRP---RNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLR 898 ++ +P P R + + + ++ +Q+ I F LL VG + Sbjct: 889 LLLRKPYGRNKPLISRTMMKNILGHAVYQLALI------------------FTLLFVGEK 930 Query: 899 AQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQ 958 Q G+ + YT F+ +++ ++ RK Sbjct: 931 M---------FQIDSGRNAPLHSPPSEHYTIIFNTFVMMQL--FNEINARKIHGERNVFD 979 Query: 959 GFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEI 1016 G FRN I ++ I + G P F+ P++ W+ + G+ V+ ++ Sbjct: 980 GIFRNPIFCTIVLGTFAIQIVIVQFGGKP--FSCSPLQLDQWMWCIFIGLGELVWGQV 1035 >gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sapiens] Length = 1170 Score = 223 bits (567), Expect = 9e-58 Identities = 173/559 (30%), Positives = 277/559 (49%), Gaps = 54/559 (9%) Query: 328 FLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSD 387 F++ + + ++V VPEGL VT+ L+ + K++ N +V++L+A ET+G+ + ICSD Sbjct: 406 FVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSD 465 Query: 388 KTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLC-NRAAFKS 446 KTGTLT NRMTV + G + Q L +VL L N + S Sbjct: 466 KTGTLTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINS 512 Query: 447 GQDAVPVPKRIV------IGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQ 500 + +P +G+ +E ALL F + R+ P+ + N + Sbjct: 513 AYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVR 572 Query: 501 LSIHTLEDPRDPRHLLVMKGAPERVLERCSSILI-KGQELPLDEQWREAF-QTAYLSLGG 558 S+ T+ + + KGA E +L +C+ IL KG+ +P + R+ +T + Sbjct: 573 KSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMAC 632 Query: 559 LGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCR 618 G R + C Y + D P + + E + + L +V + DP R VPDA+ KC+ Sbjct: 633 DGLRTI--CIAYRDFDDTEPSWDNENEIL----TELTCIAVVGIEDPVRPEVPDAIAKCK 686 Query: 619 TAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVING 678 AGI V MVTGD+ TA+AIA GI++ G + + + K+ + N Sbjct: 687 QAGITVRMVTGDNINTARAIATKCGILTPGDDFL------------CLEGKEFNRLIRN- 733 Query: 679 MQLKDMDPSELVEALRTHPEM-VFARTSPQQKLVIVESC--QRLGA---IVAVTGDGVND 732 + E + + P++ V AR+SP K +V+ +G +VAVTGDG ND Sbjct: 734 ----EKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789 Query: 733 SPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLT 792 PALKKAD+G AMGIAG+D AK A+D+IL DDNF SIV V GR ++D++ K + + LT Sbjct: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849 Query: 793 KNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRP---RN 849 N+ + ++ PL + +L++ L D F S++LA E ++ RP Sbjct: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909 Query: 850 PKRDRLVNEPLAAYSYFQI 868 P R + + + ++++Q+ Sbjct: 910 PLISRTMMKNILGHAFYQL 928 Score = 62.8 bits (151), Expect = 2e-09 Identities = 65/263 (24%), Positives = 119/263 (45%), Gaps = 32/263 (12%) Query: 51 EINDHQLSVAELEQKYQTSATKGLSASLAAELLLRD--GPNALRPPRGTPEYVKFARQLA 108 +IN H V L + +TS +GLS + A R G N + PP+ +++ + Sbjct: 43 QINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVI-PPKKPKTFLELVWEAL 101 Query: 109 GGLQCLMWVAAAICLIAFAIQASEGD--------LTT--DDN---------LYLAIALIA 149 + ++ AAI + + G+ TT D+N + ++I Sbjct: 102 QDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVII 161 Query: 150 VVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDR 209 VV+VT + +E + + + Q+ ++IR+G Q+ ++VVGD+ ++K GD Sbjct: 162 VVLVTAFNDWSKEKQFRGLQCRIEQ--EQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDL 219 Query: 210 VPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLV 269 +PAD ++ K+D SSLTGES+ +S L+ + T +EG+ + +V Sbjct: 220 LPADGILIQGNDLKIDESSLTGESDHVKKS--------LDKDPMLLSGTHVMEGSGRMVV 271 Query: 270 VNTGDRTIIGRIASLASGVENEK 292 G + G I +L E+++ Sbjct: 272 TAVGVNSQTGIILTLLGVNEDDE 294 >gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] Length = 1205 Score = 223 bits (567), Expect = 9e-58 Identities = 173/559 (30%), Positives = 277/559 (49%), Gaps = 54/559 (9%) Query: 328 FLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSD 387 F++ + + ++V VPEGL VT+ L+ + K++ N +V++L+A ET+G+ + ICSD Sbjct: 406 FVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSD 465 Query: 388 KTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLC-NRAAFKS 446 KTGTLT NRMTV + G + Q L +VL L N + S Sbjct: 466 KTGTLTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINS 512 Query: 447 GQDAVPVPKRIV------IGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQ 500 + +P +G+ +E ALL F + R+ P+ + N + Sbjct: 513 AYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVR 572 Query: 501 LSIHTLEDPRDPRHLLVMKGAPERVLERCSSILI-KGQELPLDEQWREAF-QTAYLSLGG 558 S+ T+ + + KGA E +L +C+ IL KG+ +P + R+ +T + Sbjct: 573 KSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMAC 632 Query: 559 LGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCR 618 G R + C Y + D P + + E + + L +V + DP R VPDA+ KC+ Sbjct: 633 DGLRTI--CIAYRDFDDTEPSWDNENEIL----TELTCIAVVGIEDPVRPEVPDAIAKCK 686 Query: 619 TAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVING 678 AGI V MVTGD+ TA+AIA GI++ G + + + K+ + N Sbjct: 687 QAGITVRMVTGDNINTARAIATKCGILTPGDDFL------------CLEGKEFNRLIRN- 733 Query: 679 MQLKDMDPSELVEALRTHPEM-VFARTSPQQKLVIVESC--QRLGA---IVAVTGDGVND 732 + E + + P++ V AR+SP K +V+ +G +VAVTGDG ND Sbjct: 734 ----EKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789 Query: 733 SPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLT 792 PALKKAD+G AMGIAG+D AK A+D+IL DDNF SIV V GR ++D++ K + + LT Sbjct: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849 Query: 793 KNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRP---RN 849 N+ + ++ PL + +L++ L D F S++LA E ++ RP Sbjct: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909 Query: 850 PKRDRLVNEPLAAYSYFQI 868 P R + + + ++++Q+ Sbjct: 910 PLISRTMMKNILGHAFYQL 928 Score = 62.8 bits (151), Expect = 2e-09 Identities = 65/263 (24%), Positives = 119/263 (45%), Gaps = 32/263 (12%) Query: 51 EINDHQLSVAELEQKYQTSATKGLSASLAAELLLRD--GPNALRPPRGTPEYVKFARQLA 108 +IN H V L + +TS +GLS + A R G N + PP+ +++ + Sbjct: 43 QINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVI-PPKKPKTFLELVWEAL 101 Query: 109 GGLQCLMWVAAAICLIAFAIQASEGD--------LTT--DDN---------LYLAIALIA 149 + ++ AAI + + G+ TT D+N + ++I Sbjct: 102 QDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVII 161 Query: 150 VVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDR 209 VV+VT + +E + + + Q+ ++IR+G Q+ ++VVGD+ ++K GD Sbjct: 162 VVLVTAFNDWSKEKQFRGLQCRIEQ--EQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDL 219 Query: 210 VPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLV 269 +PAD ++ K+D SSLTGES+ +S L+ + T +EG+ + +V Sbjct: 220 LPADGILIQGNDLKIDESSLTGESDHVKKS--------LDKDPMLLSGTHVMEGSGRMVV 271 Query: 270 VNTGDRTIIGRIASLASGVENEK 292 G + G I +L E+++ Sbjct: 272 TAVGVNSQTGIILTLLGVNEDDE 294 >gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] Length = 1220 Score = 221 bits (564), Expect = 2e-57 Identities = 179/621 (28%), Positives = 303/621 (48%), Gaps = 73/621 (11%) Query: 286 SGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCI--GYT------------FLRA 331 S ++ + T +A++I +++ + ++ +F++ + G T F++ Sbjct: 358 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKF 417 Query: 332 MVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGT 391 + + ++V VPEGL VT+ L+ + K++ N +V++L+A ET+G+ + ICSDKTGT Sbjct: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 477 Query: 392 LTQNRMTVSHLWF-DNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFK--SGQ 448 LT NRMTV + D H + + D L +++ + K + Sbjct: 478 LTTNRMTVVQSYLGDTHYKEIPAPSALTPKILD-------LLVHAISINSAYTTKILPPE 530 Query: 449 DAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLED 508 +P++ +G+ +E ALL F + R++ P+ + N + S+ T+ Sbjct: 531 KEGALPRQ--VGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIR 588 Query: 509 PRDPRHLLVMKGAPERVLERCSSILIKGQEL------PLDEQWREAFQTAYLSLGGLGER 562 D L KGA E +L++C++IL EL D+ R+ + ++ GL Sbjct: 589 MPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEP--MACDGLRTI 646 Query: 563 VLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGI 622 + + +D+ G D + N L +V + DP R VP+A+ KC+ AGI Sbjct: 647 CIAY-------RDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGI 699 Query: 623 RVIMVTGDHPITAKAIAASVGIISEGSETV----EDIAARLRVPVDQVNRKDARACVING 678 V MVTGD+ TA+AIAA GII G + + ++ R+R ++ ++ Sbjct: 700 TVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQE--------- 750 Query: 679 MQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE-----SCQRLGAIVAVTGDGVNDS 733 +L + P LR V AR+SP K +V+ + +VAVTGDG ND Sbjct: 751 -RLDKVWPK-----LR-----VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDG 799 Query: 734 PALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTK 793 PALKKAD+G AMGIAG+D AK A+D+IL DDNF SIV V GR ++D++ K + + LT Sbjct: 800 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTV 859 Query: 794 NIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRP---RNP 850 N+ + ++ PL + +L++ L D F S++LA E ++ +P P Sbjct: 860 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKP 919 Query: 851 KRDRLVNEPLAAYSYFQIGAI 871 R + + + ++ +Q+ I Sbjct: 920 LISRTMMKNILGHAVYQLAII 940 Score = 65.9 bits (159), Expect = 2e-10 Identities = 77/310 (24%), Positives = 137/310 (44%), Gaps = 44/310 (14%) Query: 11 SVELGPGPGGDMAAKMSKKKKAGGGGGKRKE-----KLENMKKEMEINDHQLSVAELEQK 65 S+E P P + +AGG G E +L + +I + V+ L ++ Sbjct: 8 SIEFHPKP-----QQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRR 62 Query: 66 YQTSATKGLSASLAAELLLRD--GPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICL 123 +TS T+GL+ + R G N + PP+ +++ + + ++ AAI Sbjct: 63 LKTSPTEGLADNTNDLEKRRQIYGQNFI-PPKQPKTFLQLVWEALQDVTLIILEVAAIVS 121 Query: 124 IAFAIQASEGDLTTD-------------------DNLYLAIALIAVVVVTGCFGYYQEFK 164 + + A G+ + + + +++I VV+VT + +E + Sbjct: 122 LGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQ 181 Query: 165 STNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKV 224 + + + Q+ TVIR+G Q+ LVVGD+ ++K GD +PAD ++ A K+ Sbjct: 182 FRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKI 239 Query: 225 DNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASL 284 D SSLTGES+ +S + + P+ T +EG+ + +V G + G I +L Sbjct: 240 DESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 291 Query: 285 --ASGVENEK 292 A G E EK Sbjct: 292 LGAGGEEEEK 301 >gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sapiens] Length = 1173 Score = 221 bits (564), Expect = 2e-57 Identities = 179/621 (28%), Positives = 303/621 (48%), Gaps = 73/621 (11%) Query: 286 SGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCI--GYT------------FLRA 331 S ++ + T +A++I +++ + ++ +F++ + G T F++ Sbjct: 358 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKF 417 Query: 332 MVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGT 391 + + ++V VPEGL VT+ L+ + K++ N +V++L+A ET+G+ + ICSDKTGT Sbjct: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 477 Query: 392 LTQNRMTVSHLWF-DNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFK--SGQ 448 LT NRMTV + D H + + D L +++ + K + Sbjct: 478 LTTNRMTVVQSYLGDTHYKEIPAPSALTPKILD-------LLVHAISINSAYTTKILPPE 530 Query: 449 DAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLED 508 +P++ +G+ +E ALL F + R++ P+ + N + S+ T+ Sbjct: 531 KEGALPRQ--VGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIR 588 Query: 509 PRDPRHLLVMKGAPERVLERCSSILIKGQEL------PLDEQWREAFQTAYLSLGGLGER 562 D L KGA E +L++C++IL EL D+ R+ + ++ GL Sbjct: 589 MPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEP--MACDGLRTI 646 Query: 563 VLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGI 622 + + +D+ G D + N L +V + DP R VP+A+ KC+ AGI Sbjct: 647 CIAY-------RDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGI 699 Query: 623 RVIMVTGDHPITAKAIAASVGIISEGSETV----EDIAARLRVPVDQVNRKDARACVING 678 V MVTGD+ TA+AIAA GII G + + ++ R+R ++ ++ Sbjct: 700 TVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQE--------- 750 Query: 679 MQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE-----SCQRLGAIVAVTGDGVNDS 733 +L + P LR V AR+SP K +V+ + +VAVTGDG ND Sbjct: 751 -RLDKVWPK-----LR-----VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDG 799 Query: 734 PALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTK 793 PALKKAD+G AMGIAG+D AK A+D+IL DDNF SIV V GR ++D++ K + + LT Sbjct: 800 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTV 859 Query: 794 NIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRP---RNP 850 N+ + ++ PL + +L++ L D F S++LA E ++ +P P Sbjct: 860 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKP 919 Query: 851 KRDRLVNEPLAAYSYFQIGAI 871 R + + + ++ +Q+ I Sbjct: 920 LISRTMMKNILGHAVYQLAII 940 Score = 65.9 bits (159), Expect = 2e-10 Identities = 77/310 (24%), Positives = 137/310 (44%), Gaps = 44/310 (14%) Query: 11 SVELGPGPGGDMAAKMSKKKKAGGGGGKRKE-----KLENMKKEMEINDHQLSVAELEQK 65 S+E P P + +AGG G E +L + +I + V+ L ++ Sbjct: 8 SIEFHPKP-----QQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRR 62 Query: 66 YQTSATKGLSASLAAELLLRD--GPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICL 123 +TS T+GL+ + R G N + PP+ +++ + + ++ AAI Sbjct: 63 LKTSPTEGLADNTNDLEKRRQIYGQNFI-PPKQPKTFLQLVWEALQDVTLIILEVAAIVS 121 Query: 124 IAFAIQASEGDLTTD-------------------DNLYLAIALIAVVVVTGCFGYYQEFK 164 + + A G+ + + + +++I VV+VT + +E + Sbjct: 122 LGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQ 181 Query: 165 STNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKV 224 + + + Q+ TVIR+G Q+ LVVGD+ ++K GD +PAD ++ A K+ Sbjct: 182 FRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKI 239 Query: 225 DNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASL 284 D SSLTGES+ +S + + P+ T +EG+ + +V G + G I +L Sbjct: 240 DESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 291 Query: 285 --ASGVENEK 292 A G E EK Sbjct: 292 LGAGGEEEEK 301 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,608,018 Number of Sequences: 37866 Number of extensions: 1713319 Number of successful extensions: 4692 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 63 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 4343 Number of HSP's gapped (non-prelim): 194 length of query: 1035 length of database: 18,247,518 effective HSP length: 112 effective length of query: 923 effective length of database: 14,006,526 effective search space: 12928023498 effective search space used: 12928023498 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.