Guide to the Human Genome
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Search of human proteins with 51895795

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51895795 annexin A13 isoform a [Homo sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51895795 annexin A13 isoform a [Homo sapiens]                      615   e-176
gi|51896029 annexin A13 isoform b [Homo sapiens]                      603   e-173
gi|4809279 annexin VII isoform 2 [Homo sapiens]                       311   5e-85
gi|4502111 annexin VII isoform 1 [Homo sapiens]                       311   5e-85
gi|4502105 annexin IV [Homo sapiens]                                  293   2e-79
gi|4557317 annexin A11 [Homo sapiens]                                 290   9e-79
gi|22165433 annexin A11 [Homo sapiens]                                290   9e-79
gi|22165431 annexin A11 [Homo sapiens]                                290   9e-79
gi|91807122 annexin A8L2 [Homo sapiens]                               290   2e-78
gi|91823262 annexin A8 [Homo sapiens]                                 289   2e-78
gi|149588958 annexin A8-like 1 [Homo sapiens]                         288   6e-78
gi|71773415 annexin VI isoform 2 [Homo sapiens]                       282   3e-76
gi|71773329 annexin VI isoform 1 [Homo sapiens]                       282   3e-76
gi|4502107 annexin 5 [Homo sapiens]                                   267   1e-71
gi|4826643 annexin A3 [Homo sapiens]                                  264   7e-71
gi|4502101 annexin I [Homo sapiens]                                   256   2e-68
gi|4757756 annexin A2 isoform 2 [Homo sapiens]                        254   5e-68
gi|50845386 annexin A2 isoform 2 [Homo sapiens]                       254   5e-68
gi|50845388 annexin A2 isoform 1 [Homo sapiens]                       254   5e-68
gi|209862831 annexin A2 isoform 2 [Homo sapiens]                      254   5e-68
gi|48762937 annexin A10 [Homo sapiens]                                202   2e-52
gi|145864465 annexin A9 [Homo sapiens]                                165   6e-41
gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo ...   103   2e-22
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             33   0.25 
gi|148806902 TBC1 domain family, member 12 [Homo sapiens]              33   0.43 
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    32   0.96 
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    32   0.96 
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    32   0.96 
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    32   0.96 
gi|46852390 coiled-coil domain containing 6 [Homo sapiens]             30   2.1  

>gi|51895795 annexin A13 isoform a [Homo sapiens]
          Length = 316

 Score =  615 bits (1585), Expect = e-176
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MGNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATY 60
           MGNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATY
Sbjct: 1   MGNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATY 60

Query: 61  GKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKE 120
           GKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKE
Sbjct: 61  GKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKE 120

Query: 121 IIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYD 180
           IIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYD
Sbjct: 121 IIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYD 180

Query: 181 AGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLV 240
           AGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLV
Sbjct: 181 AGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLV 240

Query: 241 RCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVR 300
           RCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVR
Sbjct: 241 RCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVR 300

Query: 301 SDTSGDFRKLLVALLH 316
           SDTSGDFRKLLVALLH
Sbjct: 301 SDTSGDFRKLLVALLH 316


>gi|51896029 annexin A13 isoform b [Homo sapiens]
          Length = 357

 Score =  603 bits (1555), Expect = e-173
 Identities = 311/311 (100%), Positives = 311/311 (100%)

Query: 6   AKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELE 65
           AKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELE
Sbjct: 47  AKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELE 106

Query: 66  EVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIK 125
           EVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIK
Sbjct: 107 EVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIK 166

Query: 126 EAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGR 185
           EAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGR
Sbjct: 167 EAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGR 226

Query: 186 WGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQD 245
           WGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQD
Sbjct: 227 WGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQD 286

Query: 246 CEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSG 305
           CEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSG
Sbjct: 287 CEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSG 346

Query: 306 DFRKLLVALLH 316
           DFRKLLVALLH
Sbjct: 347 DFRKLLVALLH 357


>gi|4809279 annexin VII isoform 2 [Homo sapiens]
          Length = 488

 Score =  311 bits (797), Expect = 5e-85
 Identities = 155/302 (51%), Positives = 217/302 (71%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           FD  RDA+ L KA KG GT+E AI+++++ R++D+RQ+IK  +K +YGK+L + LKSELS
Sbjct: 185 FDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELS 244

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           GN E+  LAL   P+ Y A  L+KAM+G GT E VLIE+LCTRTN+EI  I   YQ  F 
Sbjct: 245 GNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFG 304

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 193
           R LE D++ DTSG+ +++LVS+ Q NR+E   ++  +A +DA+ LY AGEGR GTDE  F
Sbjct: 305 RDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCF 364

Query: 194 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 253
           N +LA RS+ QLRAT +AY  +  +D+  ++  E SG ++    T+++CA +   +FAER
Sbjct: 365 NMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAER 424

Query: 254 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 313
           LY +MKGAGTD+ TL+RIVVTR+E+DL  IK  F + YQK+L  M+  DTSGD+R+LL+A
Sbjct: 425 LYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLA 484

Query: 314 LL 315
           ++
Sbjct: 485 IV 486


>gi|4502111 annexin VII isoform 1 [Homo sapiens]
          Length = 466

 Score =  311 bits (797), Expect = 5e-85
 Identities = 155/302 (51%), Positives = 217/302 (71%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           FD  RDA+ L KA KG GT+E AI+++++ R++D+RQ+IK  +K +YGK+L + LKSELS
Sbjct: 163 FDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELS 222

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           GN E+  LAL   P+ Y A  L+KAM+G GT E VLIE+LCTRTN+EI  I   YQ  F 
Sbjct: 223 GNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFG 282

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 193
           R LE D++ DTSG+ +++LVS+ Q NR+E   ++  +A +DA+ LY AGEGR GTDE  F
Sbjct: 283 RDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCF 342

Query: 194 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 253
           N +LA RS+ QLRAT +AY  +  +D+  ++  E SG ++    T+++CA +   +FAER
Sbjct: 343 NMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAER 402

Query: 254 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 313
           LY +MKGAGTD+ TL+RIVVTR+E+DL  IK  F + YQK+L  M+  DTSGD+R+LL+A
Sbjct: 403 LYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLA 462

Query: 314 LL 315
           ++
Sbjct: 463 IV 464


>gi|4502105 annexin IV [Homo sapiens]
          Length = 321

 Score =  293 bits (749), Expect = 2e-79
 Identities = 147/314 (46%), Positives = 214/314 (68%)

Query: 1   MGNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATY 60
           M  +     +  GF+   DA+ L KA KG+GT+E AII +L+ R + +RQ+I+  YK+T 
Sbjct: 3   MATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTI 62

Query: 61  GKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKE 120
           G++L + LKSELSGNFE+  + ++     Y  ++L++AMKG GTDE  LIE+L +RT +E
Sbjct: 63  GRDLIDDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEE 122

Query: 121 IIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYD 180
           I  I + YQ+ + RSLE D++ DTS   +++LVSL    R+EG+ +D  L  QDA+DLY+
Sbjct: 123 IRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYE 182

Query: 181 AGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLV 240
           AGE +WGTDE+ F  VL  R+   L   F  Y+ +  KDIE++I+ ETSG  + A L +V
Sbjct: 183 AGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV 242

Query: 241 RCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVR 300
           +C ++   YFAE+LYKSMKG GTD+ TLIR++V+RAE+D+  I+A F+  Y KSL   ++
Sbjct: 243 KCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIK 302

Query: 301 SDTSGDFRKLLVAL 314
            DTSGD+RK+L+ L
Sbjct: 303 GDTSGDYRKVLLVL 316



 Score =  103 bits (258), Expect = 2e-22
 Identities = 71/233 (30%), Positives = 120/233 (51%), Gaps = 21/233 (9%)

Query: 92  ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 151
           A+ L+KAMKGLGTDE  +I VL  R   +   I+ AY+    R L  D+K + SGN +++
Sbjct: 22  AQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQV 81

Query: 152 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 211
           +V ++                 D ++L  A +G  GTDE    E+LA R+ +++R   Q 
Sbjct: 82  IVGMMTPT-----------VLYDVQELRRAMKGA-GTDEGCLIEILASRTPEEIRRISQT 129

Query: 212 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYF--------AERLYKS-MKGAG 262
           YQ   G+ +E+ I  +TS   Q+  ++L    +D  +Y         A+ LY++  K  G
Sbjct: 130 YQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWG 189

Query: 263 TDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 315
           TDE   + ++ +R    L  +  +++   QK +   ++S+TSG F   L+A++
Sbjct: 190 TDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV 242


>gi|4557317 annexin A11 [Homo sapiens]
          Length = 505

 Score =  290 bits (743), Expect = 9e-79
 Identities = 151/313 (48%), Positives = 218/313 (69%), Gaps = 1/313 (0%)

Query: 2   GNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYG 61
           G+R     +P GFD  RDA+ L KA KG GT+E AII+ L  R++ +RQQI   +K  YG
Sbjct: 189 GSRGTITDAP-GFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYG 247

Query: 62  KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 121
           K+L + LKSELSGNFEKT LAL+  P  +   ++++A+KG+GTDE+ LIE+L +R+N+ I
Sbjct: 248 KDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHI 307

Query: 122 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 181
             +  AY+  F ++LE  ++ DTSG+ +++L+SL Q NR+E  +VD  LA +DA++LY A
Sbjct: 308 RELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAA 367

Query: 182 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 241
           GE R GTDE  FN VL  RS   L A F  YQ + G+DIE++I  E SGDL++  L +V+
Sbjct: 368 GENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVK 427

Query: 242 CAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRS 301
           C ++   +FAERL K+M+GAGT + TLIRI+V+R+E DL  I+++++  Y KSL   +  
Sbjct: 428 CLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISG 487

Query: 302 DTSGDFRKLLVAL 314
           DTSGD+RK+L+ +
Sbjct: 488 DTSGDYRKILLKI 500



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 49/162 (30%), Positives = 91/162 (56%), Gaps = 5/162 (3%)

Query: 2   GNRHAKASSPQGFDVDRDAKKLNKACKG-MGTNEAAIIEILSGRTSDERQQIKQKYKATY 60
           GNR    +        RDA++L  A +  +GT+E+    +L  R+      +  +Y+   
Sbjct: 344 GNRDESTNVDMSL-AQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMT 402

Query: 61  GKELEEVLKSELSGNFEKTALAL---LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRT 117
           G+++E+ +  E+SG+ E+  LA+   L     + A +L KAM+G GT +  LI ++ +R+
Sbjct: 403 GRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRS 462

Query: 118 NKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 159
             +++ I+  Y+R++ +SL  D+ GDTSG+ +KIL+ +   N
Sbjct: 463 ETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 26/65 (40%), Positives = 40/65 (61%)

Query: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 310
           AE L K+MKG GTDE+ +I  + +R+    Q I   F+  Y K L   ++S+ SG+F K 
Sbjct: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265

Query: 311 LVALL 315
           ++AL+
Sbjct: 266 ILALM 270


>gi|22165433 annexin A11 [Homo sapiens]
          Length = 505

 Score =  290 bits (743), Expect = 9e-79
 Identities = 151/313 (48%), Positives = 218/313 (69%), Gaps = 1/313 (0%)

Query: 2   GNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYG 61
           G+R     +P GFD  RDA+ L KA KG GT+E AII+ L  R++ +RQQI   +K  YG
Sbjct: 189 GSRGTITDAP-GFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYG 247

Query: 62  KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 121
           K+L + LKSELSGNFEKT LAL+  P  +   ++++A+KG+GTDE+ LIE+L +R+N+ I
Sbjct: 248 KDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHI 307

Query: 122 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 181
             +  AY+  F ++LE  ++ DTSG+ +++L+SL Q NR+E  +VD  LA +DA++LY A
Sbjct: 308 RELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAA 367

Query: 182 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 241
           GE R GTDE  FN VL  RS   L A F  YQ + G+DIE++I  E SGDL++  L +V+
Sbjct: 368 GENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVK 427

Query: 242 CAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRS 301
           C ++   +FAERL K+M+GAGT + TLIRI+V+R+E DL  I+++++  Y KSL   +  
Sbjct: 428 CLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISG 487

Query: 302 DTSGDFRKLLVAL 314
           DTSGD+RK+L+ +
Sbjct: 488 DTSGDYRKILLKI 500



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 49/162 (30%), Positives = 91/162 (56%), Gaps = 5/162 (3%)

Query: 2   GNRHAKASSPQGFDVDRDAKKLNKACKG-MGTNEAAIIEILSGRTSDERQQIKQKYKATY 60
           GNR    +        RDA++L  A +  +GT+E+    +L  R+      +  +Y+   
Sbjct: 344 GNRDESTNVDMSL-AQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMT 402

Query: 61  GKELEEVLKSELSGNFEKTALAL---LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRT 117
           G+++E+ +  E+SG+ E+  LA+   L     + A +L KAM+G GT +  LI ++ +R+
Sbjct: 403 GRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRS 462

Query: 118 NKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 159
             +++ I+  Y+R++ +SL  D+ GDTSG+ +KIL+ +   N
Sbjct: 463 ETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 26/65 (40%), Positives = 40/65 (61%)

Query: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 310
           AE L K+MKG GTDE+ +I  + +R+    Q I   F+  Y K L   ++S+ SG+F K 
Sbjct: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265

Query: 311 LVALL 315
           ++AL+
Sbjct: 266 ILALM 270


>gi|22165431 annexin A11 [Homo sapiens]
          Length = 505

 Score =  290 bits (743), Expect = 9e-79
 Identities = 151/313 (48%), Positives = 218/313 (69%), Gaps = 1/313 (0%)

Query: 2   GNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYG 61
           G+R     +P GFD  RDA+ L KA KG GT+E AII+ L  R++ +RQQI   +K  YG
Sbjct: 189 GSRGTITDAP-GFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYG 247

Query: 62  KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 121
           K+L + LKSELSGNFEKT LAL+  P  +   ++++A+KG+GTDE+ LIE+L +R+N+ I
Sbjct: 248 KDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHI 307

Query: 122 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 181
             +  AY+  F ++LE  ++ DTSG+ +++L+SL Q NR+E  +VD  LA +DA++LY A
Sbjct: 308 RELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAA 367

Query: 182 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 241
           GE R GTDE  FN VL  RS   L A F  YQ + G+DIE++I  E SGDL++  L +V+
Sbjct: 368 GENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVK 427

Query: 242 CAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRS 301
           C ++   +FAERL K+M+GAGT + TLIRI+V+R+E DL  I+++++  Y KSL   +  
Sbjct: 428 CLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISG 487

Query: 302 DTSGDFRKLLVAL 314
           DTSGD+RK+L+ +
Sbjct: 488 DTSGDYRKILLKI 500



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 49/162 (30%), Positives = 91/162 (56%), Gaps = 5/162 (3%)

Query: 2   GNRHAKASSPQGFDVDRDAKKLNKACKG-MGTNEAAIIEILSGRTSDERQQIKQKYKATY 60
           GNR    +        RDA++L  A +  +GT+E+    +L  R+      +  +Y+   
Sbjct: 344 GNRDESTNVDMSL-AQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMT 402

Query: 61  GKELEEVLKSELSGNFEKTALAL---LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRT 117
           G+++E+ +  E+SG+ E+  LA+   L     + A +L KAM+G GT +  LI ++ +R+
Sbjct: 403 GRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRS 462

Query: 118 NKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 159
             +++ I+  Y+R++ +SL  D+ GDTSG+ +KIL+ +   N
Sbjct: 463 ETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 26/65 (40%), Positives = 40/65 (61%)

Query: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 310
           AE L K+MKG GTDE+ +I  + +R+    Q I   F+  Y K L   ++S+ SG+F K 
Sbjct: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265

Query: 311 LVALL 315
           ++AL+
Sbjct: 266 ILALM 270


>gi|91807122 annexin A8L2 [Homo sapiens]
          Length = 327

 Score =  290 bits (741), Expect = 2e-78
 Identities = 152/307 (49%), Positives = 214/307 (69%), Gaps = 1/307 (0%)

Query: 10  SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLK 69
           S   F+ D DA+ L KA KG+GTNE AII++L+ R++ +RQQI + +KA +GK+L E LK
Sbjct: 17  SSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLK 76

Query: 70  SELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQ 129
           SELSG FE+  +AL+  P  Y A++L  AMKGLGT E V+IE+L +RT  ++  I +AY+
Sbjct: 77  SELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYE 136

Query: 130 RLFDRSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGT 188
             +  SLE D++ DTSG L++ILV LLQ +R++    VD  LA QDA+DLY AGE   GT
Sbjct: 137 EDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGENIRGT 196

Query: 189 DELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCED 248
           DE+ F  +L  RS   L   F+ Y+ +  K IE++I+ ET G L++A LT+V+C Q+   
Sbjct: 197 DEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHS 256

Query: 249 YFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFR 308
           YFAERLY +MKGAGT + TLIR +V+R+E+DL  IK  F++ Y K+LS M+  DTSGD++
Sbjct: 257 YFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYK 316

Query: 309 KLLVALL 315
             L++L+
Sbjct: 317 NALLSLV 323



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 26/66 (39%), Positives = 45/66 (68%)

Query: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 310
           AE LYK+MKG GT+E+ +I ++  R+    Q I   F+ ++ K L++ ++S+ SG F +L
Sbjct: 27  AETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERL 86

Query: 311 LVALLH 316
           +VAL++
Sbjct: 87  IVALMY 92


>gi|91823262 annexin A8 [Homo sapiens]
          Length = 327

 Score =  289 bits (740), Expect = 2e-78
 Identities = 152/307 (49%), Positives = 214/307 (69%), Gaps = 1/307 (0%)

Query: 10  SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLK 69
           S   F+ D DA+ L KA KG+GTNE AII++L+ R++ +RQQI + +KA +GK+L E LK
Sbjct: 17  SSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLK 76

Query: 70  SELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQ 129
           SELSG FE+  +AL+  P  Y A++L  AMKGLGT E V+IE+L +RT  ++  I +AY+
Sbjct: 77  SELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYE 136

Query: 130 RLFDRSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGT 188
             +  SLE D++ DTSG L++ILV LLQ +R++    VD  LA QDA+DLY AGE   GT
Sbjct: 137 EDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGT 196

Query: 189 DELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCED 248
           DE+ F  +L  RS   L   F+ Y+ +  K IE++I+ ET G L++A LT+V+C Q+   
Sbjct: 197 DEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHS 256

Query: 249 YFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFR 308
           YFAERLY +MKGAGT + TLIR +V+R+E+DL  IK  F++ Y K+LS M+  DTSGD++
Sbjct: 257 YFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYK 316

Query: 309 KLLVALL 315
             L++L+
Sbjct: 317 NALLSLV 323



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 26/66 (39%), Positives = 45/66 (68%)

Query: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 310
           AE LYK+MKG GT+E+ +I ++  R+    Q I   F+ ++ K L++ ++S+ SG F +L
Sbjct: 27  AETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERL 86

Query: 311 LVALLH 316
           +VAL++
Sbjct: 87  IVALMY 92


>gi|149588958 annexin A8-like 1 [Homo sapiens]
          Length = 327

 Score =  288 bits (736), Expect = 6e-78
 Identities = 151/307 (49%), Positives = 214/307 (69%), Gaps = 1/307 (0%)

Query: 10  SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLK 69
           S   F+ D DA+ L +A KG+GTNE AII++L+ R++ +RQQI + +KA +GK+L E LK
Sbjct: 17  SSSHFNPDPDAETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLK 76

Query: 70  SELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQ 129
           SELSG FE+  +AL+  P  Y A++L  AMKGLGT E V+IE+L +RT  ++  I +AY+
Sbjct: 77  SELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYE 136

Query: 130 RLFDRSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGT 188
             +  SLE D++ DTSG L++ILV LLQ +R++    VD  LA QDA+DLY AGE   GT
Sbjct: 137 EDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGT 196

Query: 189 DELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCED 248
           DE+ F  +L  RS   L   F+ Y+ +  K IE++I+ ET G L++A LT+V+C Q+   
Sbjct: 197 DEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHS 256

Query: 249 YFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFR 308
           YFAERLY +MKGAGT + TLIR +V+R+E+DL  IK  F++ Y K+LS M+  DTSGD++
Sbjct: 257 YFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYK 316

Query: 309 KLLVALL 315
             L++L+
Sbjct: 317 NALLSLV 323



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 25/66 (37%), Positives = 45/66 (68%)

Query: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 310
           AE LY++MKG GT+E+ +I ++  R+    Q I   F+ ++ K L++ ++S+ SG F +L
Sbjct: 27  AETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERL 86

Query: 311 LVALLH 316
           +VAL++
Sbjct: 87  IVALMY 92


>gi|71773415 annexin VI isoform 2 [Homo sapiens]
          Length = 667

 Score =  282 bits (721), Expect = 3e-76
 Identities = 139/302 (46%), Positives = 211/302 (69%)

Query: 13  GFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSEL 72
           GFD ++DA+ L  A KG G+++ AI++I++ R++ +RQ++ Q YK+ YGK+L   LK EL
Sbjct: 19  GFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYEL 78

Query: 73  SGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLF 132
           +G FE+  + L+  P+   A++++ A+ G+GTDE  LIE+L +RTN+++  +  AY+  +
Sbjct: 79  TGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAY 138

Query: 133 DRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
           +R LE+D+ GDTSG+ +K+LV LLQ  R E D V +DL  QD +DLY+AGE +WGTDE  
Sbjct: 139 ERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQ 198

Query: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
           F  +L  RS + LR  F  Y    GK IE +I  E SGD +K  L +V+C +   +YFAE
Sbjct: 199 FIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAE 258

Query: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
           RL+K+MKG GT + TLIRI+V+R+E+D+  I+  F+ KY+KSL  M+++DTSG+++K L+
Sbjct: 259 RLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLL 318

Query: 313 AL 314
            L
Sbjct: 319 KL 320



 Score =  270 bits (689), Expect = 2e-72
 Identities = 141/301 (46%), Positives = 207/301 (68%), Gaps = 1/301 (0%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           F+ D DAK L KA KG+GT+E  II+I++ R++ +RQQI+Q +K+ +G++L   LKSE+S
Sbjct: 363 FNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEIS 422

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           G+  +  L L+  P+ Y A+QL+KAM+G GTDE  LIE+L TRTN EI AI EAY+  + 
Sbjct: 423 GDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYH 482

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 193
           +SLE  +  DTSG+ ++IL+SL   +R EG + + D A +DA+++ D   G   + E  F
Sbjct: 483 KSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQEIADTPSGDKTSLETRF 541

Query: 194 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 253
             +L  RSY  LR  FQ +  +   D+E  I++E SGD++ A++ +V+  ++   +FA++
Sbjct: 542 MTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFADK 601

Query: 254 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 313
           LYKSMKGAGTDE+TL RI+V+R+E+DL  I+ +F EKY KSL   +  DTSGDF K L+A
Sbjct: 602 LYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLKALLA 661

Query: 314 L 314
           L
Sbjct: 662 L 662



 Score =  124 bits (311), Expect = 1e-28
 Identities = 98/357 (27%), Positives = 170/357 (47%), Gaps = 69/357 (19%)

Query: 9   SSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVL 68
           S+P+ F     A++L KA KG+GT +  +I I+  R+  +   I++ ++  Y K L  ++
Sbjct: 251 STPEYF-----AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMI 305

Query: 69  KSELSGNFEKTALALLDRPSEYA------------------------------------- 91
           K++ SG ++KT L L     + A                                     
Sbjct: 306 KNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNP 365

Query: 92  ---ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNL 148
              A+ L+KAMKGLGTDE  +I+++  R+N +   I++ ++  F R L +D+K + SG+L
Sbjct: 366 DADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL 425

Query: 149 KKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRAT 208
            ++++ L+              A  DAK L  A EG  GTDE A  E+LA R+  ++RA 
Sbjct: 426 ARLILGLMMPP-----------AHYDAKQLKKAMEGA-GTDEKALIEILATRTNAEIRAI 473

Query: 209 FQAYQILIGKDIEEAIEEETSGDLQKAYLTLV---------RCAQDCEDYFAERLYKSMK 259
            +AY+    K +E+A+  +TSG  ++  ++L             Q  ED  A+ +  +  
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQARED--AQEIADTPS 531

Query: 260 GAGTDEET-LIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 315
           G  T  ET  + I+ TR+   L+ +  +F +     +   ++ + SGD R   VA++
Sbjct: 532 GDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 588



 Score =  100 bits (248), Expect = 2e-21
 Identities = 66/234 (28%), Positives = 127/234 (54%), Gaps = 23/234 (9%)

Query: 92  ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 151
           A  L  AMKG G+D+  +++++ +R+N++   + ++Y+ L+ + L +D+K + +G  +++
Sbjct: 26  AEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERL 85

Query: 152 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 211
           +V L++             A  DAK++ DA  G  GTDE    E+LA R+ +Q+     A
Sbjct: 86  IVGLMRPP-----------AYCDAKEIKDAISGI-GTDEKCLIEILASRTNEQMHQLVAA 133

Query: 212 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKS----------MKGA 261
           Y+    +D+E  I  +TSG  QK  + L++  ++ +D  +E L +           +K  
Sbjct: 134 YKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW- 192

Query: 262 GTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 315
           GTDE   I I+  R++  L+ +  ++ +   K +   +R + SGDF KL++A++
Sbjct: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVV 246



 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 47/143 (32%), Positives = 85/143 (59%), Gaps = 4/143 (2%)

Query: 173 QDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDL 232
           QDA+ LY A +G +G+D+ A  +++  RS +Q +   Q+Y+ L GKD+   ++ E +G  
Sbjct: 24  QDAEALYTAMKG-FGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKF 82

Query: 233 QKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 292
           ++  + L+R    C+   A+ +  ++ G GTDE+ LI I+ +R    +  + A +++ Y+
Sbjct: 83  ERLIVGLMRPPAYCD---AKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYE 139

Query: 293 KSLSDMVRSDTSGDFRKLLVALL 315
           + L   +  DTSG F+K+LV LL
Sbjct: 140 RDLEADIIGDTSGHFQKMLVVLL 162


>gi|71773329 annexin VI isoform 1 [Homo sapiens]
          Length = 673

 Score =  282 bits (721), Expect = 3e-76
 Identities = 139/302 (46%), Positives = 211/302 (69%)

Query: 13  GFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSEL 72
           GFD ++DA+ L  A KG G+++ AI++I++ R++ +RQ++ Q YK+ YGK+L   LK EL
Sbjct: 19  GFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYEL 78

Query: 73  SGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLF 132
           +G FE+  + L+  P+   A++++ A+ G+GTDE  LIE+L +RTN+++  +  AY+  +
Sbjct: 79  TGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAY 138

Query: 133 DRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
           +R LE+D+ GDTSG+ +K+LV LLQ  R E D V +DL  QD +DLY+AGE +WGTDE  
Sbjct: 139 ERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQ 198

Query: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
           F  +L  RS + LR  F  Y    GK IE +I  E SGD +K  L +V+C +   +YFAE
Sbjct: 199 FIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAE 258

Query: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
           RL+K+MKG GT + TLIRI+V+R+E+D+  I+  F+ KY+KSL  M+++DTSG+++K L+
Sbjct: 259 RLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLL 318

Query: 313 AL 314
            L
Sbjct: 319 KL 320



 Score =  263 bits (672), Expect = 2e-70
 Identities = 141/307 (45%), Positives = 207/307 (67%), Gaps = 7/307 (2%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           F+ D DAK L KA KG+GT+E  II+I++ R++ +RQQI+Q +K+ +G++L   LKSE+S
Sbjct: 363 FNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEIS 422

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           G+  +  L L+  P+ Y A+QL+KAM+G GTDE  LIE+L TRTN EI AI EAY+  + 
Sbjct: 423 GDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYH 482

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAK------DLYDAGEGRWG 187
           +SLE  +  DTSG+ ++IL+SL   +R EG + + D A +DA+      ++ D   G   
Sbjct: 483 KSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQVAAEILEIADTPSGDKT 541

Query: 188 TDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCE 247
           + E  F  +L  RSY  LR  FQ +  +   D+E  I++E SGD++ A++ +V+  ++  
Sbjct: 542 SLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKP 601

Query: 248 DYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDF 307
            +FA++LYKSMKGAGTDE+TL RI+V+R+E+DL  I+ +F EKY KSL   +  DTSGDF
Sbjct: 602 LFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDF 661

Query: 308 RKLLVAL 314
            K L+AL
Sbjct: 662 LKALLAL 668



 Score =  120 bits (300), Expect = 2e-27
 Identities = 97/361 (26%), Positives = 170/361 (47%), Gaps = 71/361 (19%)

Query: 9   SSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVL 68
           S+P+ F     A++L KA KG+GT +  +I I+  R+  +   I++ ++  Y K L  ++
Sbjct: 251 STPEYF-----AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMI 305

Query: 69  KSELSGNFEKTALALLDRPSEYA------------------------------------- 91
           K++ SG ++KT L L     + A                                     
Sbjct: 306 KNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNP 365

Query: 92  ---ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNL 148
              A+ L+KAMKGLGTDE  +I+++  R+N +   I++ ++  F R L +D+K + SG+L
Sbjct: 366 DADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL 425

Query: 149 KKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRAT 208
            ++++ L+              A  DAK L  A EG  GTDE A  E+LA R+  ++RA 
Sbjct: 426 ARLILGLMMPP-----------AHYDAKQLKKAMEGA-GTDEKALIEILATRTNAEIRAI 473

Query: 209 FQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRC-----------AQDCEDYFAE--RLY 255
            +AY+    K +E+A+  +TSG  ++  ++L              A++     AE   + 
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIA 533

Query: 256 KSMKGAGTDEET-LIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 314
            +  G  T  ET  + I+ TR+   L+ +  +F +     +   ++ + SGD R   VA+
Sbjct: 534 DTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAI 593

Query: 315 L 315
           +
Sbjct: 594 V 594



 Score =  100 bits (248), Expect = 2e-21
 Identities = 66/234 (28%), Positives = 127/234 (54%), Gaps = 23/234 (9%)

Query: 92  ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 151
           A  L  AMKG G+D+  +++++ +R+N++   + ++Y+ L+ + L +D+K + +G  +++
Sbjct: 26  AEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERL 85

Query: 152 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 211
           +V L++             A  DAK++ DA  G  GTDE    E+LA R+ +Q+     A
Sbjct: 86  IVGLMRPP-----------AYCDAKEIKDAISGI-GTDEKCLIEILASRTNEQMHQLVAA 133

Query: 212 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKS----------MKGA 261
           Y+    +D+E  I  +TSG  QK  + L++  ++ +D  +E L +           +K  
Sbjct: 134 YKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW- 192

Query: 262 GTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 315
           GTDE   I I+  R++  L+ +  ++ +   K +   +R + SGDF KL++A++
Sbjct: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVV 246



 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 47/143 (32%), Positives = 85/143 (59%), Gaps = 4/143 (2%)

Query: 173 QDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDL 232
           QDA+ LY A +G +G+D+ A  +++  RS +Q +   Q+Y+ L GKD+   ++ E +G  
Sbjct: 24  QDAEALYTAMKG-FGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKF 82

Query: 233 QKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 292
           ++  + L+R    C+   A+ +  ++ G GTDE+ LI I+ +R    +  + A +++ Y+
Sbjct: 83  ERLIVGLMRPPAYCD---AKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYE 139

Query: 293 KSLSDMVRSDTSGDFRKLLVALL 315
           + L   +  DTSG F+K+LV LL
Sbjct: 140 RDLEADIIGDTSGHFQKMLVVLL 162


>gi|4502107 annexin 5 [Homo sapiens]
          Length = 320

 Score =  267 bits (682), Expect = 1e-71
 Identities = 136/302 (45%), Positives = 202/302 (66%)

Query: 13  GFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSEL 72
           GFD   DA+ L KA KG+GT+E +I+ +L+ R++ +RQ+I   +K  +G++L + LKSEL
Sbjct: 14  GFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSEL 73

Query: 73  SGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLF 132
           +G FEK  +AL+     Y A +L+ A+KG GT+E VL E++ +RT +E+ AIK+ Y+  +
Sbjct: 74  TGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEY 133

Query: 133 DRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
             SLE DV GDTSG  +++LV LLQANR+    +D+    QDA+ L+ AGE +WGTDE  
Sbjct: 134 GSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEK 193

Query: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
           F  +   RS   LR  F  Y  + G  IEE I+ ETSG+L++  L +V+  +    Y AE
Sbjct: 194 FITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAE 253

Query: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
            LY +MKGAGTD+ TLIR++V+R+E+DL  I+ +F++ +  SL  M++ DTSGD++K L+
Sbjct: 254 TLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALL 313

Query: 313 AL 314
            L
Sbjct: 314 LL 315



 Score =  103 bits (258), Expect = 2e-22
 Identities = 71/233 (30%), Positives = 128/233 (54%), Gaps = 21/233 (9%)

Query: 92  ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 151
           A  L+KAMKGLGTDE  ++ +L +R+N +   I  A++ LF R L  D+K + +G  +K+
Sbjct: 21  AETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKL 80

Query: 152 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 211
           +V+L++ +R             DA +L  A +G  GT+E    E++A R+ ++LRA  Q 
Sbjct: 81  IVALMKPSRL-----------YDAYELKHALKGA-GTNEKVLTEIIASRTPEELRAIKQV 128

Query: 212 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCE--------DYFAERLYKSMKGA-G 262
           Y+   G  +E+ +  +TSG  Q+  + L++  +D +        +  A+ L+++ +   G
Sbjct: 129 YEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWG 188

Query: 263 TDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 315
           TDEE  I I  TR+   L+ +  K+       + + +  +TSG+  +LL+A++
Sbjct: 189 TDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVV 241



 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 50/142 (35%), Positives = 84/142 (59%), Gaps = 4/142 (2%)

Query: 174 DAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQ 233
           DA+ L  A +G  GTDE +   +L  RS  Q +    A++ L G+D+ + ++ E +G  +
Sbjct: 20  DAETLRKAMKGL-GTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFE 78

Query: 234 KAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQK 293
           K  + L++ ++    Y A  L  ++KGAGT+E+ L  I+ +R   +L+ IK  ++E+Y  
Sbjct: 79  KLIVALMKPSRL---YDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGS 135

Query: 294 SLSDMVRSDTSGDFRKLLVALL 315
           SL D V  DTSG ++++LV LL
Sbjct: 136 SLEDDVVGDTSGYYQRMLVVLL 157


>gi|4826643 annexin A3 [Homo sapiens]
          Length = 323

 Score =  264 bits (675), Expect = 7e-71
 Identities = 136/314 (43%), Positives = 211/314 (67%), Gaps = 1/314 (0%)

Query: 1   MGNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATY 60
           +G+R      P  F    DA+ + KA +G+GT+E  +I IL+ R++ +RQ I ++Y+A Y
Sbjct: 6   VGHRGTVRDYPD-FSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAY 64

Query: 61  GKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKE 120
           GKEL++ LK +LSG+FE   +AL+  P+ + A+QL+K+MKG GT+E  LIE+L TRT+++
Sbjct: 65  GKELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQ 124

Query: 121 IIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYD 180
           +  I +AY  ++ +SL  D+  +TSG+ +K L++L    R+E   VD+ LA QDA+ LY 
Sbjct: 125 MKDISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYK 184

Query: 181 AGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLV 240
           AGE RWGTDE  F E+L  RS+ QL+ TF  Y+ +  KDI ++I+ E SG  +   L +V
Sbjct: 185 AGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIV 244

Query: 241 RCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVR 300
            C ++   + AERL++++KG GTDE TL RI+V+R+E+DL  I+ +F++ Y  SL   ++
Sbjct: 245 NCVRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIK 304

Query: 301 SDTSGDFRKLLVAL 314
           SDTSGD+   L+ +
Sbjct: 305 SDTSGDYEITLLKI 318



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 27/65 (41%), Positives = 40/65 (61%)

Query: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 310
           AE + K+++G GTDE+ LI I+  R+    Q I  ++Q  Y K L D ++ D SG F  L
Sbjct: 24  AEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHL 83

Query: 311 LVALL 315
           +VAL+
Sbjct: 84  MVALV 88


>gi|4502101 annexin I [Homo sapiens]
          Length = 346

 Score =  256 bits (654), Expect = 2e-68
 Identities = 135/301 (44%), Positives = 191/301 (63%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           F+   D   L+KA    G +EA II+IL+ R + +RQQIK  Y    GK L+E LK  L+
Sbjct: 42  FNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALT 101

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           G+ E+  LALL  P+++ A +L+ AMKGLGTDE  LIE+L +RTNKEI  I   Y+    
Sbjct: 102 GHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 193
           R L  D+  DTSG+ +  L+SL + +R+E   V++DLA  DA+ LY+AGE R GTD   F
Sbjct: 162 RDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVF 221

Query: 194 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 253
           N +L  RSY QLR  FQ Y      D+ + ++ E  GD++K    +V+CA     +FAE+
Sbjct: 222 NTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEK 281

Query: 254 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 313
           L+++MKG GT  + LIRI+V+R+E+D+  IKA +Q+ Y  SL   +  +T GD+ K+LVA
Sbjct: 282 LHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVA 341

Query: 314 L 314
           L
Sbjct: 342 L 342



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 72/263 (27%), Positives = 128/263 (48%), Gaps = 22/263 (8%)

Query: 62  KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 121
           +E  + +KS   G     +      PS   A  L KA+   G DE+ +I++L  R N + 
Sbjct: 19  QEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAA-LHKAIMVKGVDEATIIDILTKRNNAQR 77

Query: 122 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 181
             IK AY +   + L+  +K   +G+L++++++LL           K  A  DA +L  A
Sbjct: 78  QQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL-----------KTPAQFDADELRAA 126

Query: 182 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 241
            +G  GTDE    E+LA R+ K++R   + Y+  + +D+ + I  +TSGD + A L+L +
Sbjct: 127 MKGL-GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185

Query: 242 --------CAQDCEDYFAERLYKS-MKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 292
                     +D  D  A  LY++  +  GTD      I+ TR+   L+ +  K+ +  +
Sbjct: 186 GDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSK 245

Query: 293 KSLSDMVRSDTSGDFRKLLVALL 315
             ++ ++  +  GD  K L A++
Sbjct: 246 HDMNKVLDLELKGDIEKCLTAIV 268



 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 51/164 (31%), Positives = 88/164 (53%), Gaps = 11/164 (6%)

Query: 6   AKASSPQGFDV-----DRDAKKLNKAC-KGMGTNEAAIIEILSGRTSDERQQIKQKYKAT 59
           AK    + F V     D DA+ L +A  +  GT+      IL+ R+  + +++ QKY   
Sbjct: 184 AKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKY 243

Query: 60  YGKELEEVLKSELSGNFEKTALALL----DRPSEYAARQLQKAMKGLGTDESVLIEVLCT 115
              ++ +VL  EL G+ EK   A++     +P+ + A +L +AMKG+GT    LI ++ +
Sbjct: 244 SKHDMNKVLDLELKGDIEKCLTAIVKCATSKPA-FFAEKLHQAMKGVGTRHKALIRIMVS 302

Query: 116 RTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 159
           R+  ++  IK  YQ+++  SL   +  +T G+ +KILV+L   N
Sbjct: 303 RSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346


>gi|4757756 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  254 bits (650), Expect = 5e-68
 Identities = 133/302 (44%), Positives = 195/302 (64%), Gaps = 1/302 (0%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           FD +RDA  +  A K  G +E  I+ IL+ R++ +RQ I   Y+    KEL   LKS LS
Sbjct: 33  FDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALS 92

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           G+ E   L LL  P++Y A +L+ +MKGLGTDE  LIE++C+RTN+E+  I   Y+ ++ 
Sbjct: 93  GHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYK 152

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
             LE D+  DTSG+ +K++V+L +  R E G  +D +L  QDA+DLYDAG  R GTD   
Sbjct: 153 TDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPK 212

Query: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
           +  ++ +RS   L+  F  Y+     D+ E+I +E  GDL+ A+L LV+C Q+   YFA+
Sbjct: 213 WISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFAD 272

Query: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
           RLY SMKG GT ++ LIRI+V+R+EVD+  I+++F+ KY KSL   ++ DT GD++K L+
Sbjct: 273 RLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALL 332

Query: 313 AL 314
            L
Sbjct: 333 YL 334


>gi|50845386 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  254 bits (650), Expect = 5e-68
 Identities = 133/302 (44%), Positives = 195/302 (64%), Gaps = 1/302 (0%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           FD +RDA  +  A K  G +E  I+ IL+ R++ +RQ I   Y+    KEL   LKS LS
Sbjct: 33  FDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALS 92

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           G+ E   L LL  P++Y A +L+ +MKGLGTDE  LIE++C+RTN+E+  I   Y+ ++ 
Sbjct: 93  GHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYK 152

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
             LE D+  DTSG+ +K++V+L +  R E G  +D +L  QDA+DLYDAG  R GTD   
Sbjct: 153 TDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPK 212

Query: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
           +  ++ +RS   L+  F  Y+     D+ E+I +E  GDL+ A+L LV+C Q+   YFA+
Sbjct: 213 WISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFAD 272

Query: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
           RLY SMKG GT ++ LIRI+V+R+EVD+  I+++F+ KY KSL   ++ DT GD++K L+
Sbjct: 273 RLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALL 332

Query: 313 AL 314
            L
Sbjct: 333 YL 334


>gi|50845388 annexin A2 isoform 1 [Homo sapiens]
          Length = 357

 Score =  254 bits (650), Expect = 5e-68
 Identities = 133/302 (44%), Positives = 195/302 (64%), Gaps = 1/302 (0%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           FD +RDA  +  A K  G +E  I+ IL+ R++ +RQ I   Y+    KEL   LKS LS
Sbjct: 51  FDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALS 110

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           G+ E   L LL  P++Y A +L+ +MKGLGTDE  LIE++C+RTN+E+  I   Y+ ++ 
Sbjct: 111 GHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYK 170

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
             LE D+  DTSG+ +K++V+L +  R E G  +D +L  QDA+DLYDAG  R GTD   
Sbjct: 171 TDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPK 230

Query: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
           +  ++ +RS   L+  F  Y+     D+ E+I +E  GDL+ A+L LV+C Q+   YFA+
Sbjct: 231 WISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFAD 290

Query: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
           RLY SMKG GT ++ LIRI+V+R+EVD+  I+++F+ KY KSL   ++ DT GD++K L+
Sbjct: 291 RLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALL 350

Query: 313 AL 314
            L
Sbjct: 351 YL 352


>gi|209862831 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  254 bits (650), Expect = 5e-68
 Identities = 133/302 (44%), Positives = 195/302 (64%), Gaps = 1/302 (0%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           FD +RDA  +  A K  G +E  I+ IL+ R++ +RQ I   Y+    KEL   LKS LS
Sbjct: 33  FDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALS 92

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           G+ E   L LL  P++Y A +L+ +MKGLGTDE  LIE++C+RTN+E+  I   Y+ ++ 
Sbjct: 93  GHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYK 152

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
             LE D+  DTSG+ +K++V+L +  R E G  +D +L  QDA+DLYDAG  R GTD   
Sbjct: 153 TDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPK 212

Query: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
           +  ++ +RS   L+  F  Y+     D+ E+I +E  GDL+ A+L LV+C Q+   YFA+
Sbjct: 213 WISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFAD 272

Query: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
           RLY SMKG GT ++ LIRI+V+R+EVD+  I+++F+ KY KSL   ++ DT GD++K L+
Sbjct: 273 RLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALL 332

Query: 313 AL 314
            L
Sbjct: 333 YL 334


>gi|48762937 annexin A10 [Homo sapiens]
          Length = 324

 Score =  202 bits (515), Expect = 2e-52
 Identities = 109/301 (36%), Positives = 183/301 (60%), Gaps = 1/301 (0%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           F+   DA+ L  A +G   ++  +I IL+ R + +R  I + Y++ YG++L   ++ +LS
Sbjct: 17  FNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLS 76

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
            +F+     L+  P  Y A +L  AMKG+GTDE+ LIE+L +RTN EI  ++EAY   + 
Sbjct: 77  DHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREAYCLQYS 136

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 193
            +L+ D+  +TSG+ +  L++L+Q  R EG   D  +A QDA  L++A + + G  +   
Sbjct: 137 NNLQEDIYSETSGHFRDTLMNLVQGTREEG-YTDPAMAAQDAMVLWEACQQKTGEHKTML 195

Query: 194 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 253
             +L  +SY+QLR  FQ +Q + G+D+ +AI E   G  Q+  + +V C +D   YFA R
Sbjct: 196 QMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVLCVRDKPAYFAYR 255

Query: 254 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 313
           LY ++   G   +T+IRI++ R+E+DL  I+ +++E+Y KSL   +R+  SG ++K L+A
Sbjct: 256 LYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIRNFASGHYKKALLA 315

Query: 314 L 314
           +
Sbjct: 316 I 316



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 59/233 (25%), Positives = 116/233 (49%), Gaps = 22/233 (9%)

Query: 92  ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 151
           A+ L  A++G   D+ +LI +L  R N + + I EAYQ ++ R L  D++   S + K +
Sbjct: 23  AQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFKDV 82

Query: 152 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 211
           +  L+                 DA +L+ A +G  GTDE    E+LA R+  ++    +A
Sbjct: 83  MAGLMYPPPL-----------YDAHELWHAMKGV-GTDENCLIEILASRTNGEIFQMREA 130

Query: 212 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYF--------AERLYKSMKGAGT 263
           Y +    +++E I  ETSG  +   + LV+  ++ E Y         A  L+++ +    
Sbjct: 131 YCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTRE-EGYTDPAMAAQDAMVLWEACQQKTG 189

Query: 264 DEETLIRIVV-TRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 315
           + +T++++++  ++   L+ +  +FQ    + + D +     G F++LLVA++
Sbjct: 190 EHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIV 242



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 41/142 (28%), Positives = 71/142 (50%), Gaps = 4/142 (2%)

Query: 174 DAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQ 233
           DA+ L  A +G +  D+     +L +R   Q     +AYQ + G+D+   + E+ S   +
Sbjct: 22  DAQMLGGALQG-FDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFK 80

Query: 234 KAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQK 293
                L+        Y A  L+ +MKG GTDE  LI I+ +R   ++  ++  +  +Y  
Sbjct: 81  DVMAGLM---YPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREAYCLQYSN 137

Query: 294 SLSDMVRSDTSGDFRKLLVALL 315
           +L + + S+TSG FR  L+ L+
Sbjct: 138 NLQEDIYSETSGHFRDTLMNLV 159


>gi|145864465 annexin A9 [Homo sapiens]
          Length = 345

 Score =  165 bits (417), Expect = 6e-41
 Identities = 97/302 (32%), Positives = 176/302 (58%), Gaps = 4/302 (1%)

Query: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73
           F VD+DA++L +A  G G + +AI+++L+ R+ ++RQ I + ++    ++L + L++ LS
Sbjct: 41  FSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALS 100

Query: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133
           GN E+  +ALL   +++ A++L+ A+K   +   V IE+L TRT  ++      Y+  F 
Sbjct: 101 GNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQECLAVYKHNFQ 160

Query: 134 RSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGTDELA 192
                D+  +TSG L+ +L++L +  R+     +D +LA QD + L  A EG   + E  
Sbjct: 161 VEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQALQRA-EG--PSREET 217

Query: 193 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 252
           +  V  +R+ + L   F  YQ   G+++EEA++    GD Q A L L    ++   YFA+
Sbjct: 218 WVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFAD 277

Query: 253 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 312
           +L+++++    + + LIRI+++R E DL  I+A+F++K+ KSL   ++    GD +  L+
Sbjct: 278 KLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALL 337

Query: 313 AL 314
           AL
Sbjct: 338 AL 339



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 20/68 (29%), Positives = 39/68 (57%)

Query: 248 DYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDF 307
           D  A+RL +++ G G D   ++ ++  R+    Q I   FQE+ Q+ L   +++  SG+ 
Sbjct: 44  DKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALSGNL 103

Query: 308 RKLLVALL 315
            ++++ALL
Sbjct: 104 ERIVMALL 111


>gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo
           sapiens]
          Length = 112

 Score =  103 bits (258), Expect = 2e-22
 Identities = 51/109 (46%), Positives = 74/109 (67%)

Query: 191 LAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYF 250
           + F  +L  RS   L   F+ Y+ +  K IE++I+ ET G L++A LT+V+C Q+   YF
Sbjct: 1   MKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYF 60

Query: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMV 299
           AERLY +MKGAGT + TLIR +V+R+E+DL  IK  F++ Y K+LS M+
Sbjct: 61  AERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 29/104 (27%), Positives = 57/104 (54%), Gaps = 3/104 (2%)

Query: 38  IEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALL---DRPSEYAARQ 94
           I IL  R++    ++ ++Y+    K +E+ +KSE  G+ E+  L ++        Y A +
Sbjct: 4   ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAER 63

Query: 95  LQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLES 138
           L  AMKG GT +  LI  + +R+  ++  IK  +++++ ++L S
Sbjct: 64  LYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSS 107



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 28/115 (24%), Positives = 59/115 (51%), Gaps = 9/115 (7%)

Query: 110 IEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKD 169
           I +LCTR+   ++ + E Y+++ ++S+E  +K +T G+L++ ++++++  +N        
Sbjct: 4   ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN-------- 55

Query: 170 LAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAI 224
           L    A+ LY A +G  GT +      +  RS   L      ++ + GK +   I
Sbjct: 56  LHSYFAERLYYAMKGA-GTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109



 Score = 32.3 bits (72), Expect = 0.57
 Identities = 16/49 (32%), Positives = 26/49 (53%)

Query: 20  AKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVL 68
           A++L  A KG GT +  +I  +  R+  +   IK  +K  YGK L  ++
Sbjct: 61  AERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 33.5 bits (75), Expect = 0.25
 Identities = 58/261 (22%), Positives = 108/261 (41%), Gaps = 18/261 (6%)

Query: 24   NKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALAL 83
            NK  + + T +A     L   ++ + QQ++++ KA    + E+ LK +   N EK+ LA 
Sbjct: 1074 NKLIQELKTAKAT----LEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVN-EKSKLAE 1128

Query: 84   LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGD 143
            ++   E   RQ ++  K     +S  +E +     KEI  +K+A Q L  + LE   K D
Sbjct: 1129 IE---EIKCRQEKEITKLNEELKSHKLESI-----KEITNLKDAKQLLIQQKLELQGKAD 1180

Query: 144  T----SGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAK 199
            +        K+    L    + E +++ K+   ++AK   +  E   G  +   NE    
Sbjct: 1181 SLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLT 1240

Query: 200  RSYKQLRATFQAYQILIGKDIEEAIE-EETSGDLQKAYLTLVRCAQDCEDYFAERLYKSM 258
                 L       +           E E+ + DL+     L    Q+ +D     L + +
Sbjct: 1241 MQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCL 1300

Query: 259  KGAGTDEETLIRIVVTRAEVD 279
            KG G  E+   +++  + ++D
Sbjct: 1301 KGEGEIEKLQTKVLELQRKLD 1321


>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
          Length = 775

 Score = 32.7 bits (73), Expect = 0.43
 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 12/84 (14%)

Query: 52  IKQKYKATYGKELEEVLKSELSGNFE-----KTALALLDRPSEYAARQLQKAMKGLGTDE 106
           I+Q+Y+A  G+  +   +S    NFE      TAL L DRPS   A+ +++A++      
Sbjct: 363 IQQEYEARTGRTCKPPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALR----HR 418

Query: 107 SVLIEVLCTRTNKEIIAIKEAYQR 130
               E++     +E   IKEA++R
Sbjct: 419 QEYDEMVAEAKKRE---IKEAHKR 439


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 31.6 bits (70), Expect = 0.96
 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 32   TNEAAIIEILSGRTSDERQQIKQKYKATYGK--ELEEVLKSELSGNFE--KTALALLDRP 87
            +NE A     + +    RQQ++++ K    K  E+E  +KS+        +  +A L+  
Sbjct: 1770 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829

Query: 88   SEYAARQLQKAMKGLGTDESVLIEVL 113
             E  AR+ Q A K L   +  L E+L
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEIL 1855


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 31.6 bits (70), Expect = 0.96
 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 32   TNEAAIIEILSGRTSDERQQIKQKYKATYGK--ELEEVLKSELSGNFE--KTALALLDRP 87
            +NE A     + +    RQQ++++ K    K  E+E  +KS+        +  +A L+  
Sbjct: 1777 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836

Query: 88   SEYAARQLQKAMKGLGTDESVLIEVL 113
             E  AR+ Q A K L   +  L E+L
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEIL 1862


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 31.6 bits (70), Expect = 0.96
 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 32   TNEAAIIEILSGRTSDERQQIKQKYKATYGK--ELEEVLKSELSGNFE--KTALALLDRP 87
            +NE A     + +    RQQ++++ K    K  E+E  +KS+        +  +A L+  
Sbjct: 1777 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836

Query: 88   SEYAARQLQKAMKGLGTDESVLIEVL 113
             E  AR+ Q A K L   +  L E+L
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEIL 1862


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 31.6 bits (70), Expect = 0.96
 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 32   TNEAAIIEILSGRTSDERQQIKQKYKATYGK--ELEEVLKSELSGNFE--KTALALLDRP 87
            +NE A     + +    RQQ++++ K    K  E+E  +KS+        +  +A L+  
Sbjct: 1770 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829

Query: 88   SEYAARQLQKAMKGLGTDESVLIEVL 113
             E  AR+ Q A K L   +  L E+L
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEIL 1855


>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
          Length = 474

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 20/80 (25%), Positives = 42/80 (52%), Gaps = 6/80 (7%)

Query: 189 DELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCED 248
           +EL       ++  K L+   + Y++       +A++EE   DL+KA +T+   A+  E+
Sbjct: 57  EELTNRLASLQQENKVLKIELETYKLKC-----KALQEENR-DLRKASVTIQARAEQEEE 110

Query: 249 YFAERLYKSMKGAGTDEETL 268
           + +  L+K ++    ++ETL
Sbjct: 111 FISNTLFKKIQALQKEKETL 130


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,278,265
Number of Sequences: 37866
Number of extensions: 420321
Number of successful extensions: 1286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 973
Number of HSP's gapped (non-prelim): 87
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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