Guide to the Human Genome
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Search of human proteins with 5174519

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
         (430 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174519 SMAD family member 9 isoform b [Homo sapiens]              915   0.0  
gi|187828357 SMAD family member 9 isoform a [Homo sapiens]            896   0.0  
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]             751   0.0  
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]              751   0.0  
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]        736   0.0  
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]        736   0.0  
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]        736   0.0  
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [...   555   e-158
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi...   554   e-158
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]   538   e-153
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]    538   e-153
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3...   479   e-135
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2...   404   e-113
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4...   339   2e-93
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]   236   4e-62
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]             140   3e-33
gi|5174517 SMAD family member 7 [Homo sapiens]                        119   4e-27
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]            100   4e-21
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s...    39   0.007
gi|189181750 human immunodeficiency virus type I enhancer bindin...    39   0.012
gi|116089331 human immunodeficiency virus type I enhancer bindin...    39   0.012
gi|239756018 PREDICTED: similar to hCG1790963 [Homo sapiens]           37   0.035
gi|239750538 PREDICTED: hypothetical protein XP_002347438 [Homo ...    37   0.035
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                37   0.035
gi|4758666 LATS homolog 1 [Homo sapiens]                               37   0.045
gi|50301236 forkhead box J1 [Homo sapiens]                             36   0.077
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       36   0.077
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [...    35   0.10 
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [...    35   0.10 
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          35   0.10 

>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
          Length = 430

 Score =  915 bits (2364), Expect = 0.0
 Identities = 430/430 (100%), Positives = 430/430 (100%)

Query: 1   MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 60
           MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS
Sbjct: 1   MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 60

Query: 61  CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 120
           CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK
Sbjct: 61  CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 120

Query: 121 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 180
           QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS
Sbjct: 121 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 180

Query: 181 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSDFRPVCYEEPQHWCSVA 240
           FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSDFRPVCYEEPQHWCSVA
Sbjct: 181 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSDFRPVCYEEPQHWCSVA 240

Query: 241 YYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVH 300
           YYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVH
Sbjct: 241 YYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVH 300

Query: 301 LYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQS 360
           LYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQS
Sbjct: 301 LYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQS 360

Query: 361 VHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMG 420
           VHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMG
Sbjct: 361 VHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMG 420

Query: 421 SPHNPISSVS 430
           SPHNPISSVS
Sbjct: 421 SPHNPISSVS 430


>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
          Length = 467

 Score =  896 bits (2316), Expect = 0.0
 Identities = 430/467 (92%), Positives = 430/467 (92%), Gaps = 37/467 (7%)

Query: 1   MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 60
           MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS
Sbjct: 1   MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 60

Query: 61  CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 120
           CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK
Sbjct: 61  CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 120

Query: 121 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 180
           QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS
Sbjct: 121 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 180

Query: 181 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHS----------------- 223
           FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHS                 
Sbjct: 181 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ 240

Query: 224 --------------------DFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG 263
                               DFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG
Sbjct: 241 SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG 300

Query: 264 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR 323
           FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR
Sbjct: 301 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR 360

Query: 324 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK 383
           NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK
Sbjct: 361 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK 420

Query: 384 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 421 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467


>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  751 bits (1939), Expect = 0.0
 Identities = 364/465 (78%), Positives = 390/465 (83%), Gaps = 43/465 (9%)

Query: 7   ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPS 66
           ++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALSCPGQPS
Sbjct: 3   VTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPS 62

Query: 67  KCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 126
            CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI
Sbjct: 63  NCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 122

Query: 127 NPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC 186
           NPYHY+RVE+PVLPPVLVPRHSEYNPQ SLLA+FR+    +EP MP NAT+PDSFQQP  
Sbjct: 123 NPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDSFQQPNS 181

Query: 187 SALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQ----------------------- 221
              P SP+ ++  SP ++S  YPHSP S S+P SP+Q                       
Sbjct: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240

Query: 222 ----------------HSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFT 265
                             D + V YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGFT
Sbjct: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300

Query: 266 DPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNC 325
           DPSNN+NRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRNC
Sbjct: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360

Query: 326 NYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGW 385
           NY HGFHP TVCKIPSGCSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKGW
Sbjct: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420

Query: 386 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465


>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  751 bits (1939), Expect = 0.0
 Identities = 364/465 (78%), Positives = 390/465 (83%), Gaps = 43/465 (9%)

Query: 7   ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPS 66
           ++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALSCPGQPS
Sbjct: 3   VTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPS 62

Query: 67  KCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 126
            CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI
Sbjct: 63  NCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 122

Query: 127 NPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC 186
           NPYHY+RVE+PVLPPVLVPRHSEYNPQ SLLA+FR+    +EP MP NAT+PDSFQQP  
Sbjct: 123 NPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDSFQQPNS 181

Query: 187 SALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQ----------------------- 221
              P SP+ ++  SP ++S  YPHSP S S+P SP+Q                       
Sbjct: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240

Query: 222 ----------------HSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFT 265
                             D + V YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGFT
Sbjct: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300

Query: 266 DPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNC 325
           DPSNN+NRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRNC
Sbjct: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360

Query: 326 NYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGW 385
           NY HGFHP TVCKIPSGCSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKGW
Sbjct: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420

Query: 386 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465


>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  736 bits (1901), Expect = 0.0
 Identities = 356/466 (76%), Positives = 388/466 (83%), Gaps = 42/466 (9%)

Query: 5   TPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQ 64
           T ++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALS PGQ
Sbjct: 2   TSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQ 61

Query: 65  PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 124
           PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEV
Sbjct: 62  PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEV 121

Query: 125 CINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQP 184
           CINPYHY+RVE+PVLPPVLVPRH+E+NPQ SLL +FR+ S H+EP MP NAT+PDSF QP
Sbjct: 122 CINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLS-HNEPHMPQNATFPDSFHQP 180

Query: 185 PCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQ----------------------- 221
             +  P SP+  +  SP +++YP+SP S S P SP+Q                       
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQDNSQ 239

Query: 222 -----------------HSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGF 264
                              D +PV YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGF
Sbjct: 240 PMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGF 299

Query: 265 TDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRN 324
           TDPSNN++RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRN
Sbjct: 300 TDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRN 359

Query: 325 CNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKG 384
           CN+ HGFHP TVCKIPS CSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKG
Sbjct: 360 CNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKG 419

Query: 385 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 420 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  736 bits (1901), Expect = 0.0
 Identities = 356/466 (76%), Positives = 388/466 (83%), Gaps = 42/466 (9%)

Query: 5   TPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQ 64
           T ++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALS PGQ
Sbjct: 2   TSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQ 61

Query: 65  PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 124
           PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEV
Sbjct: 62  PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEV 121

Query: 125 CINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQP 184
           CINPYHY+RVE+PVLPPVLVPRH+E+NPQ SLL +FR+ S H+EP MP NAT+PDSF QP
Sbjct: 122 CINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLS-HNEPHMPQNATFPDSFHQP 180

Query: 185 PCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQ----------------------- 221
             +  P SP+  +  SP +++YP+SP S S P SP+Q                       
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQDNSQ 239

Query: 222 -----------------HSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGF 264
                              D +PV YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGF
Sbjct: 240 PMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGF 299

Query: 265 TDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRN 324
           TDPSNN++RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRN
Sbjct: 300 TDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRN 359

Query: 325 CNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKG 384
           CN+ HGFHP TVCKIPS CSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKG
Sbjct: 360 CNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKG 419

Query: 385 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 420 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  736 bits (1901), Expect = 0.0
 Identities = 356/466 (76%), Positives = 388/466 (83%), Gaps = 42/466 (9%)

Query: 5   TPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQ 64
           T ++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALS PGQ
Sbjct: 2   TSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQ 61

Query: 65  PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 124
           PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEV
Sbjct: 62  PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEV 121

Query: 125 CINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQP 184
           CINPYHY+RVE+PVLPPVLVPRH+E+NPQ SLL +FR+ S H+EP MP NAT+PDSF QP
Sbjct: 122 CINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLS-HNEPHMPQNATFPDSFHQP 180

Query: 185 PCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQ----------------------- 221
             +  P SP+  +  SP +++YP+SP S S P SP+Q                       
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQDNSQ 239

Query: 222 -----------------HSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGF 264
                              D +PV YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGF
Sbjct: 240 PMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGF 299

Query: 265 TDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRN 324
           TDPSNN++RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRN
Sbjct: 300 TDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRN 359

Query: 325 CNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKG 384
           CN+ HGFHP TVCKIPS CSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKG
Sbjct: 360 CNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKG 419

Query: 385 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 420 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
           [Homo sapiens]
          Length = 425

 Score =  555 bits (1429), Expect = e-158
 Identities = 277/436 (63%), Positives = 331/436 (75%), Gaps = 23/436 (5%)

Query: 7   ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63
           +SS+  FT P VKRLLGWK+G++   EEKW EKAV SLVKKLKK  G +DELE+A++   
Sbjct: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59

Query: 64  QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123
             +KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F  K+ E
Sbjct: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119

Query: 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQ 183
           VC+NPYHY+RVETPVLPPVLVPRH+E   +   L  +     HS   +P N  +P   + 
Sbjct: 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE- 171

Query: 184 PPCSALPPSPSHAF-----SQSPCTASYPHSPGSPS---EPESP-YQHSDFRPVCYEEPQ 234
            P S +P +P   +       S    ++    GSP+    P SP + + D +PV Y EP 
Sbjct: 172 -PQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230

Query: 235 HWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRH 294
            WCS++YYELN RVGETF AS  S+ +DGFTDPSN+  RFCLGLLSNVNRN+ +E TRRH
Sbjct: 231 FWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRH 289

Query: 295 IGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFA 354
           IG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA
Sbjct: 290 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 349

Query: 355 QLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDK 414
            LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDK
Sbjct: 350 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 409

Query: 415 VLTQMGSPHNPISSVS 430
           VLTQMGSP    SSVS
Sbjct: 410 VLTQMGSPSIRCSSVS 425


>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
           sapiens]
          Length = 437

 Score =  554 bits (1427), Expect = e-158
 Identities = 281/447 (62%), Positives = 330/447 (73%), Gaps = 33/447 (7%)

Query: 7   ISSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDSLVKKLKKKKGAMD 53
           +SS+  FT P VKRLLGWK             Q  +EEKW EKAV SLVKKLKK  G +D
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59

Query: 54  ELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
           ELE+A++     +KCVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK +E C
Sbjct: 60  ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119

Query: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPH 173
           E+ F  K+ EVC+NPYHY+RVETPVLPPVLVPRH+E   +L  L  +     HS   +P 
Sbjct: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYT----HS---IPE 172

Query: 174 NATYPDSFQQPPCSALPPSPSHAF-----SQSPCTASYPHSPGSPSEPE----SPYQHS- 223
           N  +P   + P  + +P +P   +       S    +     GSP+E      SP  HS 
Sbjct: 173 NTNFPAGIE-PQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSL 231

Query: 224 DFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVN 283
           D +PV Y EP  WCS+AYYELN RVGETF AS  S+ +DGFTDPSN+  RFCLGLLSNVN
Sbjct: 232 DLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSE-RFCLGLLSNVN 290

Query: 284 RNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGC 343
           RN+T+E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC
Sbjct: 291 RNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 350

Query: 344 SLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 403
           +LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+
Sbjct: 351 NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIEL 410

Query: 404 HLHGPLQWLDKVLTQMGSPHNPISSVS 430
           HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 411 HLNGPLQWLDKVLTQMGSPSVRCSSMS 437


>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  538 bits (1386), Expect = e-153
 Identities = 281/477 (58%), Positives = 330/477 (69%), Gaps = 63/477 (13%)

Query: 7   ISSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDSLVKKLKKKKGAMD 53
           +SS+  FT P VKRLLGWK             Q  +EEKW EKAV SLVKKLKK  G +D
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59

Query: 54  ELERALSCPGQPSKCVTIP------------------------------RSLDGRLQVSH 83
           ELE+A++     +KCVTIP                              RSLDGRLQVSH
Sbjct: 60  ELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSH 119

Query: 84  RKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVL 143
           RKGLPHVIYCR+WRWPDL SHHELK +E CE+ F  K+ EVC+NPYHY+RVETPVLPPVL
Sbjct: 120 RKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVL 179

Query: 144 VPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAF-----S 198
           VPRH+E   +L  L  +     HS   +P N  +P   + P  + +P +P   +      
Sbjct: 180 VPRHTEILTELPPLDDYT----HS---IPENTNFPAGIE-PQSNYIPETPPPGYISEDGE 231

Query: 199 QSPCTASYPHSPGSPSEPE----SPYQHS-DFRPVCYEEPQHWCSVAYYELNNRVGETFQ 253
            S    +     GSP+E      SP  HS D +PV Y EP  WCS+AYYELN RVGETF 
Sbjct: 232 TSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFH 291

Query: 254 ASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECV 313
           AS  S+ +DGFTDPSN+  RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AEC+
Sbjct: 292 ASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECL 350

Query: 314 SDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTK 373
           SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+
Sbjct: 351 SDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTR 410

Query: 374 MCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 411 MCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467


>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  538 bits (1386), Expect = e-153
 Identities = 281/477 (58%), Positives = 330/477 (69%), Gaps = 63/477 (13%)

Query: 7   ISSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDSLVKKLKKKKGAMD 53
           +SS+  FT P VKRLLGWK             Q  +EEKW EKAV SLVKKLKK  G +D
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59

Query: 54  ELERALSCPGQPSKCVTIP------------------------------RSLDGRLQVSH 83
           ELE+A++     +KCVTIP                              RSLDGRLQVSH
Sbjct: 60  ELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSH 119

Query: 84  RKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVL 143
           RKGLPHVIYCR+WRWPDL SHHELK +E CE+ F  K+ EVC+NPYHY+RVETPVLPPVL
Sbjct: 120 RKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVL 179

Query: 144 VPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAF-----S 198
           VPRH+E   +L  L  +     HS   +P N  +P   + P  + +P +P   +      
Sbjct: 180 VPRHTEILTELPPLDDYT----HS---IPENTNFPAGIE-PQSNYIPETPPPGYISEDGE 231

Query: 199 QSPCTASYPHSPGSPSEPE----SPYQHS-DFRPVCYEEPQHWCSVAYYELNNRVGETFQ 253
            S    +     GSP+E      SP  HS D +PV Y EP  WCS+AYYELN RVGETF 
Sbjct: 232 TSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFH 291

Query: 254 ASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECV 313
           AS  S+ +DGFTDPSN+  RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AEC+
Sbjct: 292 ASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECL 350

Query: 314 SDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTK 373
           SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+
Sbjct: 351 SDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTR 410

Query: 374 MCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 411 MCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467


>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
           [Homo sapiens]
          Length = 381

 Score =  479 bits (1232), Expect = e-135
 Identities = 236/367 (64%), Positives = 279/367 (76%), Gaps = 19/367 (5%)

Query: 73  RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYR 132
           RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F  K+ EVC+NPYHY+
Sbjct: 25  RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84

Query: 133 RVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPS 192
           RVETPVLPPVLVPRH+E   +   L  +     HS   +P N  +P   +  P S +P +
Sbjct: 85  RVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE--PQSNIPET 135

Query: 193 PSHAF-----SQSPCTASYPHSPGSPS---EPESP-YQHSDFRPVCYEEPQHWCSVAYYE 243
           P   +       S    ++    GSP+    P SP + + D +PV Y EP  WCS++YYE
Sbjct: 136 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 195

Query: 244 LNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYY 303
           LN RVGETF AS  S+ +DGFTDPSN+  RFCLGLLSNVNRN+ +E TRRHIG+GV LYY
Sbjct: 196 LNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYY 254

Query: 304 VGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHH 363
           +GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ 
Sbjct: 255 IGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQ 314

Query: 364 GFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPH 423
           GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP 
Sbjct: 315 GFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS 374

Query: 424 NPISSVS 430
              SSVS
Sbjct: 375 IRCSSVS 381


>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
           [Homo sapiens]
          Length = 320

 Score =  404 bits (1038), Expect = e-113
 Identities = 203/330 (61%), Positives = 244/330 (73%), Gaps = 19/330 (5%)

Query: 110 LECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEP 169
           +E CEF F  K+ EVC+NPYHY+RVETPVLPPVLVPRH+E   +   L  +     HS  
Sbjct: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS-- 54

Query: 170 LMPHNATYPDSFQQPPCSALPPSPSHAF-----SQSPCTASYPHSPGSPS---EPESP-Y 220
            +P N  +P   +  P S +P +P   +       S    ++    GSP+    P SP +
Sbjct: 55  -IPENTNFPAGIE--PQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAH 111

Query: 221 QHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLS 280
            + D +PV Y EP  WCS++YYELN RVGETF AS  S+ +DGFTDPSN+  RFCLGLLS
Sbjct: 112 NNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLS 170

Query: 281 NVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIP 340
           NVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP
Sbjct: 171 NVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIP 230

Query: 341 SGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCW 400
            GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCW
Sbjct: 231 PGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCW 290

Query: 401 IEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           IE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 291 IELHLNGPLQWLDKVLTQMGSPSIRCSSVS 320


>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
           [Homo sapiens]
          Length = 230

 Score =  339 bits (870), Expect = 2e-93
 Identities = 161/223 (72%), Positives = 186/223 (83%), Gaps = 2/223 (0%)

Query: 209 SPGSPSEPESP-YQHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDP 267
           SP     P SP + + D +PV Y EP  WCS++YYELN RVGETF AS  S+ +DGFTDP
Sbjct: 9   SPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDP 68

Query: 268 SNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNY 327
           SN+  RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN 
Sbjct: 69  SNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQ 127

Query: 328 QHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGA 387
           ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGA
Sbjct: 128 RYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGA 187

Query: 388 EYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
           EY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 188 EYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230


>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
          Length = 552

 Score =  236 bits (601), Expect = 4e-62
 Identities = 179/526 (34%), Positives = 242/526 (46%), Gaps = 126/526 (23%)

Query: 18  VKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG-QPSKCVTIPRSLD 76
           V  L+  +QG E E +A++A++SLVKKLK+KK  +D L  A++  G  PSKCVTI R+LD
Sbjct: 20  VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79

Query: 77  GRLQVSHRKGLPHVIYCRVWRWPDLQSHH-----------ELKPLECCEFPF-------- 117
           GRLQV+ RKG PHVIY R+WRWPDL  +            +LK    C  P+        
Sbjct: 80  GRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVSP 139

Query: 118 ------------------------------------GSKQKEVCINPYHYRRVETPVLPP 141
                                               G   + +   P +    ET   P 
Sbjct: 140 GIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPA 199

Query: 142 VLVPRHSEYN-----PQLSLLAKFRSASL----HSEPLMPHNATYPDSFQQPPCSALPPS 192
           +L P  S        P + + +  + AS+    HSE L+   A+ P   QQ       P+
Sbjct: 200 LLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLL-QIASGPQPGQQQNGFTGQPA 258

Query: 193 PSHAFSQSPCTASY--PHSPGSPSEPESPYQHSD-----------------FRPVC--YE 231
             H  S +  T S   P++P  P       QH                   F+P    + 
Sbjct: 259 TYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHP 318

Query: 232 EPQHWCSVAYYELNNRVGETFQASSRS--VLIDGFTDPSNNRNRFCLGLLSNVNRNSTIE 289
            P++WCS+AY+E++ +VGETF+  S    V +DG+ DPS   +RFCLG LSNV+R   IE
Sbjct: 319 APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQLSNVHRTEAIE 377

Query: 290 NTRRHIGKGVHLYYVG-GEVYAECVSDSSIFVQSRNCNYQHGFHPA-TVCKIPSGCSLKV 347
             R HIGKGV L   G G+V+  C+SD ++FVQS   + + G  P   V KI     +KV
Sbjct: 378 RARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKV 437

Query: 348 FN--------NQLFAQLLAQSVHHGFEV--------------------------VYELTK 373
           F+         Q  A   A +      V                          V +L +
Sbjct: 438 FDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRR 497

Query: 374 MCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 419
           +C +RMSFVKGWG +Y RQ +  TPCWIEIHLH  LQ LD+VL  M
Sbjct: 498 LCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543


>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
          Length = 496

 Score =  140 bits (352), Expect = 3e-33
 Identities = 119/374 (31%), Positives = 169/374 (45%), Gaps = 61/374 (16%)

Query: 40  SLVKKLKKKKGAMDELERAL-SCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 98
           SL+K+LK++  ++D L  A+ S  G P  CV +PR+    L++  +   P ++  R++RW
Sbjct: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232

Query: 99  PDLQSHHELKPL-ECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLL 157
           PDLQ   ELKPL  C  F   +    VC NPYH+ R+  P  PP                
Sbjct: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---------------- 276

Query: 158 AKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHA-FSQSPCTASYPHSPGSPSEP 216
                                     PP S L P   +     S  T SY  +  + S  
Sbjct: 277 --------------------------PPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLI 310

Query: 217 ESPYQHSD--FRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRF 274
            +P + SD    P    +P HWCSVAY+E   RVG  +    ++V I  F D       F
Sbjct: 311 TAPGEFSDASMSPDA-TKPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSG-F 366

Query: 275 CLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPA 334
           CLG L+   R+ ++  TR  IG G+ L      V+A    +  IFV S   +   G    
Sbjct: 367 CLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGG-RAL 425

Query: 335 TVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDV 394
            V K+P G S+KVF+ +  + L         +  Y+     ++R+SF KGWG  Y RQ +
Sbjct: 426 VVRKVPPGYSIKVFDFER-SGLQHAPEPDAADGPYDPN---SVRISFAKGWGPCYSRQFI 481

Query: 395 TSTPCWIEIHLHGP 408
           TS PCW+EI L+ P
Sbjct: 482 TSCPCWLEILLNNP 495


>gi|5174517 SMAD family member 7 [Homo sapiens]
          Length = 426

 Score =  119 bits (299), Expect = 4e-27
 Identities = 108/375 (28%), Positives = 163/375 (43%), Gaps = 62/375 (16%)

Query: 40  SLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRL-----------QVSHRKGLP 88
           S++KKLK+++  +  L+   S  G  + C+ +P  LD RL           Q      LP
Sbjct: 98  SVLKKLKERQLEL-LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156

Query: 89  HVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHS 148
            ++ C+V+RWPDL+   E+K L CCE       + VC NP+H  R+              
Sbjct: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRL-------------- 201

Query: 149 EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPH 208
                           L S P  P  + YP  F +P        PS A +      +Y  
Sbjct: 202 --------------CELESPP--PPYSRYPMDFLKPTADCPDAVPSSAETGG---TNYL- 241

Query: 209 SPGSPSEPESPYQHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPS 268
           +PG  S+ +   +  D          HWC VAY+E   RVG  +     S  +D F D  
Sbjct: 242 APGGLSDSQLLLEPGD--------RSHWCVVAYWEEKTRVGRLYCVQEPS--LDIFYDLP 291

Query: 269 NNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQ 328
              N FCLG L++ N++  ++  R  IG G+ L      V+    S   IF++S   +  
Sbjct: 292 QG-NGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNP 350

Query: 329 HGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAE 388
                  V K+  G S+K F+ +    L   + H   E + +     T+++SFVKGWG  
Sbjct: 351 DS-RTLLVHKVFPGFSIKAFDYEKAYSLQRPNDH---EFMQQPWTGFTVQISFVKGWGQC 406

Query: 389 YHRQDVTSTPCWIEI 403
           Y RQ ++S PCW+E+
Sbjct: 407 YTRQFISSCPCWLEV 421


>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
          Length = 235

 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 78/228 (34%), Positives = 109/228 (47%), Gaps = 12/228 (5%)

Query: 184 PPCSALPPSPSHA-FSQSPCTASYPHSPGSPSEPESPYQHSD--FRPVCYEEPQHWCSVA 240
           PP S L P   +     S  T SY  +  + S   +P + SD    P    +P HWCSVA
Sbjct: 16  PPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDA-TKPSHWCSVA 74

Query: 241 YYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVH 300
           Y+E   RVG  +    ++V I  F D       FCLG L+   R+ ++  TR  IG G+ 
Sbjct: 75  YWEHRTRVGRLYAVYDQAVSI--FYDLPQGSG-FCLGQLNLEQRSESVRRTRSKIGFGIL 131

Query: 301 LYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQS 360
           L      V+A    +  IFV S   +   G     V K+P G S+KVF+ +  + L    
Sbjct: 132 LSKEPDGVWAYNRGEHPIFVNSPTLDAPGG-RALVVRKVPPGYSIKVFDFER-SGLQHAP 189

Query: 361 VHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGP 408
                +  Y+     ++R+SF KGWG  Y RQ +TS PCW+EI L+ P
Sbjct: 190 EPDAADGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 234


>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
           sapiens]
          Length = 486

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 12/93 (12%)

Query: 132 RRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPP 191
           +++ +   PPV  P  SE  P        R++  H  PL+P   T P+  ++PP  ALPP
Sbjct: 296 KKISSEAWPPVGTPPSSESEP-------VRTSREHPVPLLPIRQTLPEDNEEPP--ALPP 346

Query: 192 SPSHAF--SQSPCTASYPHSPGSPS-EPESPYQ 221
                    + P   + P     P  EPE+ Y+
Sbjct: 347 RTLEGLQVEEEPVYEAEPEPEPEPEPEPENDYE 379


>gi|189181750 human immunodeficiency virus type I enhancer binding
           protein 3 b [Homo sapiens]
          Length = 2405

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 11/74 (14%)

Query: 145 PRHSEYNPQLSLLAKFRSASLHSEPLMPHNA-TYPD----SFQQPPCSALPPSP---SHA 196
           PR S  + + S+ +    +SL+ EPL  H+  T P+    S Q PP +A PP P   SH+
Sbjct: 486 PRRSSLSRRSSMESP--KSSLYREPLSSHSEKTKPEQSLLSLQHPPSTA-PPVPLLRSHS 542

Query: 197 FSQSPCTASYPHSP 210
              + CT S PH P
Sbjct: 543 MPSAACTISTPHHP 556


>gi|116089331 human immunodeficiency virus type I enhancer binding
           protein 3 [Homo sapiens]
          Length = 2406

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 11/74 (14%)

Query: 145 PRHSEYNPQLSLLAKFRSASLHSEPLMPHNA-TYPD----SFQQPPCSALPPSP---SHA 196
           PR S  + + S+ +    +SL+ EPL  H+  T P+    S Q PP +A PP P   SH+
Sbjct: 486 PRRSSLSRRSSMESP--KSSLYREPLSSHSEKTKPEQSLLSLQHPPSTA-PPVPLLRSHS 542

Query: 197 FSQSPCTASYPHSP 210
              + CT S PH P
Sbjct: 543 MPSAACTISTPHHP 556


>gi|239756018 PREDICTED: similar to hCG1790963 [Homo sapiens]
          Length = 196

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 13/86 (15%)

Query: 166 HSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQS-------PCTASYPHSPG-----SP 213
           HS+     +   P + ++ PCSAL PS    FS S       P +   P+SP      SP
Sbjct: 56  HSDSHSLRDTAEPGAMEELPCSALVPSLETCFSSSERPANSRPPSRWAPYSPAASQPQSP 115

Query: 214 SEPESPYQHSDFRPVCYEEPQHWCSV 239
            +P    QHS   P   E+P H  S+
Sbjct: 116 GDPTPLEQHSGEEP-SEEKPHHDASL 140


>gi|239750538 PREDICTED: hypothetical protein XP_002347438 [Homo
           sapiens]
          Length = 196

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 13/86 (15%)

Query: 166 HSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQS-------PCTASYPHSPG-----SP 213
           HS+     +   P + ++ PCSAL PS    FS S       P +   P+SP      SP
Sbjct: 56  HSDSHSLRDTAEPGAMEELPCSALVPSLETCFSSSERPANSRPPSRWAPYSPAASQPQSP 115

Query: 214 SEPESPYQHSDFRPVCYEEPQHWCSV 239
            +P    QHS   P   E+P H  S+
Sbjct: 116 GDPTPLEQHSGEEP-SEEKPHHDASL 140


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 9/94 (9%)

Query: 135 ETPVLPPVLVPRHSEYNPQLSLLAKFRSASL----HSEPLMPHNATYPDSFQQPPCSALP 190
           E+P  PP   P  S     +S    +  ASL    H  P  P         Q P  S+ P
Sbjct: 761 ESPQSPPE-GPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSP-VSSFP 818

Query: 191 PSPSHAFSQSPCTASYPHSPG---SPSEPESPYQ 221
            S S + SQS   +S+P S     S S PESP Q
Sbjct: 819 SSTSSSLSQSSPVSSFPSSTSSSLSKSSPESPLQ 852


>gi|4758666 LATS homolog 1 [Homo sapiens]
          Length = 1130

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 9/95 (9%)

Query: 128 PYHYRRVETPVLPPVLVPRHSEYNPQLSLLAK---FRSASLHSEPLMPHNATYPDSFQQP 184
           P    RV  P L   L P H  + PQ     +   F   +  +  +MP  A  P+ +Q P
Sbjct: 497 PVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPN-YQGP 555

Query: 185 PCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESP 219
           P    PP P H   Q+P    Y  S   PS+ + P
Sbjct: 556 P----PPYPKHLLHQNPSVPPY-ESISKPSKEDQP 585


>gi|50301236 forkhead box J1 [Homo sapiens]
          Length = 421

 Score = 35.8 bits (81), Expect = 0.077
 Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 3/46 (6%)

Query: 169 PLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPS 214
           P +P   T P  + Q P SA P SP  A    P     PH+PG P+
Sbjct: 50  PALPPGGTDPHGYHQVPGSAAPGSPLAA---DPACLGQPHTPGKPT 92


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 35.8 bits (81), Expect = 0.077
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 1/57 (1%)

Query: 164 SLHSEPL-MPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESP 219
           S+HS    +P    YP +F Q   + +PPSP H       T   P  P  P+ P  P
Sbjct: 898 SIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQP 954



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 23/92 (25%), Positives = 34/92 (36%), Gaps = 2/92 (2%)

Query: 137  PVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHA 196
            P + P  VP    +  Q ++ A     +L  +P +P     P     PP   LPP P+  
Sbjct: 917  PQMAPTDVPPSPHHTVQ-NMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRP 975

Query: 197  FSQ-SPCTASYPHSPGSPSEPESPYQHSDFRP 227
                 P     P  P  P +P  P +    +P
Sbjct: 976  PQPVLPPQPMLPPQPVLPPQPALPVRPEPLQP 1007



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 33/104 (31%), Positives = 36/104 (34%), Gaps = 23/104 (22%)

Query: 134  VETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSP 193
            V +P LP VL+P   E  PQ        SAS+ S P        P         A PP P
Sbjct: 1049 VLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPP---------ANPPLP 1099

Query: 194  SHAFSQSPC-------------TASYPHSPGSPSEPESPYQHSD 224
                  SPC              AS    PG P   ES Y  SD
Sbjct: 1100 GGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCES-YGGSD 1142


>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
           [Homo sapiens]
          Length = 650

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 12/92 (13%)

Query: 162 SASLHSEPLMPHNA-TYPDSF-QQPPCSALPPSPSHAFSQSPCTASYPHSPGSPS--EPE 217
           SASL   P  P  A T P S  Q PP +   PS     + +P    Y  S GSP+   P 
Sbjct: 417 SASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPT 476

Query: 218 SPYQHSDFRPVCYEEPQHWCSV------AYYE 243
           SP  +  F P     PQH  ++      AYYE
Sbjct: 477 SPVSNQGFSP--GSSPQHTSTLGSVFGDAYYE 506



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 146 RHSEYNPQLSLLAKFRSA----SLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSP 201
           R  + +P LS L+    A    +L  E  +P+        QQPP    PP P    SQ P
Sbjct: 337 RRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQP 396

Query: 202 CTASYPHSP 210
                P +P
Sbjct: 397 PPPPPPQAP 405


>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
           [Homo sapiens]
          Length = 634

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 12/92 (13%)

Query: 162 SASLHSEPLMPHNA-TYPDSF-QQPPCSALPPSPSHAFSQSPCTASYPHSPGSPS--EPE 217
           SASL   P  P  A T P S  Q PP +   PS     + +P    Y  S GSP+   P 
Sbjct: 401 SASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPT 460

Query: 218 SPYQHSDFRPVCYEEPQHWCSV------AYYE 243
           SP  +  F P     PQH  ++      AYYE
Sbjct: 461 SPVSNQGFSP--GSSPQHTSTLGSVFGDAYYE 490



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 146 RHSEYNPQLSLLAKFRSA----SLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSP 201
           R  + +P LS L+    A    +L  E  +P+        QQPP    PP P    SQ P
Sbjct: 321 RRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQP 380

Query: 202 CTASYPHSP 210
                P +P
Sbjct: 381 PPPPPPQAP 389


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 26/82 (31%), Positives = 33/82 (40%), Gaps = 11/82 (13%)

Query: 140 PPVLVPRHS--------EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPP 191
           PP L P  S         + P L L+ +  S  L S P  P   T   +   PP S  PP
Sbjct: 412 PPALKPLSSLSTHHPPSAHPPPLQLMPQ--SQPLPSSPAQPPGLTQSQNLPPPPASH-PP 468

Query: 192 SPSHAFSQSPCTASYPHSPGSP 213
           +  H  +  P  A +P  PG P
Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGP 490


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,846,820
Number of Sequences: 37866
Number of extensions: 1024580
Number of successful extensions: 5017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 123
Number of HSP's that attempted gapping in prelim test: 4724
Number of HSP's gapped (non-prelim): 359
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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