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Search of human proteins with 5174391
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174391 aldo-keto reductase family 1, member A1 [Homo
sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] 671 0.0
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] 671 0.0
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens] 325 3e-89
gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi... 313 1e-85
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo... 301 4e-82
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 271 6e-73
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 270 1e-72
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 270 1e-72
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens] 270 1e-72
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 266 1e-71
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] 257 1e-68
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ... 249 2e-66
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] 108 8e-24
gi|4504825 potassium voltage-gated channel, shaker-related subfa... 45 7e-05
gi|27436969 potassium voltage-gated channel, shaker-related subf... 45 7e-05
gi|27436964 potassium voltage-gated channel, shaker-related subf... 44 1e-04
gi|27436962 potassium voltage-gated channel, shaker-related subf... 44 1e-04
gi|27436966 potassium voltage-gated channel, shaker-related subf... 44 1e-04
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens] 43 3e-04
gi|27436971 potassium voltage-gated channel, shaker-related subf... 37 0.024
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s... 37 0.031
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s... 35 0.091
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens] 33 0.26
gi|4504011 glutamate-cysteine ligase regulatory protein [Homo sa... 31 1.3
gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E... 30 2.2
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa... 30 2.9
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa... 30 2.9
gi|24308241 zinc finger and BTB domain containing 2 [Homo sapiens] 29 6.5
>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 671 bits (1730), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL 60
MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL 60
Query: 61 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER 120
KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
Sbjct: 61 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER 120
Query: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240
AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
Sbjct: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240
Query: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 300
YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
Sbjct: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 300
Query: 301 PMLTVDGKRVPRDAGHPLYPFNDPY 325
PMLTVDGKRVPRDAGHPLYPFNDPY
Sbjct: 301 PMLTVDGKRVPRDAGHPLYPFNDPY 325
>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 671 bits (1730), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL 60
MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL 60
Query: 61 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER 120
KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
Sbjct: 61 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER 120
Query: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
Sbjct: 121 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Query: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240
AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
Sbjct: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240
Query: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 300
YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
Sbjct: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 300
Query: 301 PMLTVDGKRVPRDAGHPLYPFNDPY 325
PMLTVDGKRVPRDAGHPLYPFNDPY
Sbjct: 301 PMLTVDGKRVPRDAGHPLYPFNDPY 325
>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
Length = 316
Score = 325 bits (833), Expect = 3e-89
Identities = 161/325 (49%), Positives = 226/325 (69%), Gaps = 12/325 (3%)
Query: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 62
AS +LL+ G KMP++GLGTWKS PGQV AVK A+ VGYRHIDCA +Y NE E+G A++E
Sbjct: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61
Query: 63 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122
+ + V REELF+ SKLW T H V+ A +KTL+DL+L+YLDLYL+HWP F+ G
Sbjct: 62 KLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 180
FP + G + T+ +TW A+E LV +GLV+A+G+SNFN Q++ IL+ ++ P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240
AV Q+ECHPYL Q +LI +CQ++G+ VTAYSPLGS DR W P++P LLE+P + A+A K
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
Query: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 300
+ ++ AQ+L+R+ +QR ++ IPKS+TP RI +N KVFDF S ++M L + N+NWR +
Sbjct: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-VC 299
Query: 301 PMLTVDGKRVPRDAGHPLYPFNDPY 325
+L+ H YPF++ +
Sbjct: 300 ALLSC--------TSHKDYPFHEEF 316
>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
sapiens]
Length = 316
Score = 313 bits (803), Expect = 1e-85
Identities = 153/297 (51%), Positives = 209/297 (70%), Gaps = 3/297 (1%)
Query: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 62
A+ V L T KMP++GLGTWKS G+VK AVK A+ GYRHIDCA +Y NE E+GEA++E
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
Query: 63 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122
+ KAV RE+LF+ SKLW T V A KTL DL+L YLD+YL+HWP F+ GD
Sbjct: 62 KIQE-KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120
Query: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 180
+ FPK+ G + + W+A+E LV +GLV+ALG+SNF+ QI+ +L+ ++ P
Sbjct: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180
Query: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240
QVECHPYL Q +LI +C ++G+ VTAYSPLGS DR W P++P LLE+P + +A K
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240
Query: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297
+ ++ AQ+L+R+ +QR VI IPKS+TP+RI++NI+VFDF S EEM + + N+NWR
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297
>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
sapiens]
Length = 316
Score = 301 bits (772), Expect = 4e-82
Identities = 148/297 (49%), Positives = 206/297 (69%), Gaps = 3/297 (1%)
Query: 3 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 62
A+ V L T KMP++GLGTW+S G+VK AVK A+ YRHIDCA Y N+ E+GEA++E
Sbjct: 2 ATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQE 61
Query: 63 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122
+ KAV RE+LF+ SK+W T V A KTL DL+L YLD+YL+HWP F+ GD
Sbjct: 62 KIQE-KAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGD 120
Query: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 180
+ FPK+ G + + + W+A+E LV +GLV+ALG+SNFN QI+ +L+ ++ P
Sbjct: 121 DFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKP 180
Query: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240
QVECHPYL Q +LI +C ++G+ VTAYSPLGS DR W P++P LLE+P + +A K
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240
Query: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297
+ ++ AQ+L+R+ +QR V IPKS+TP+ I++NI+VFDF S EEM + + N+NWR
Sbjct: 241 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWR 297
>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
Length = 323
Score = 271 bits (693), Expect = 6e-73
Identities = 145/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)
Query: 5 CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
CV L+ G MP++G GT+ +E + KA A K A+ G+RHID A +Y NE ++G A++
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
+ G +V RE++F TSKLW H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 67 SKIADG-SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179
+ PK+ +G I +D+ TW+A+E GL +++G+SNFN RQ++ IL+ + +
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238
P QVECHPY Q +L+ C+++ + + AYS LGS + W DP+ PVLLE+PV+ ALA
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
Query: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298
+K+ R+PA I LR+Q+QR V+ + KS RI QN++VF+F + EEMK ++ LN+N RY
Sbjct: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
Query: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325
LT+D AG P YPF+D Y
Sbjct: 306 ----LTLD-----IFAGPPNYPFSDEY 323
>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 270 bits (691), Expect = 1e-72
Identities = 144/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)
Query: 5 CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
CV L+ G MP++G GT+ +E + KA AVK A+ G+ HID A +Y NE ++G A++
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
Query: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
+ G +V RE++F TSKLW+ H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 67 SKIADG-SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179
+ PK+ +G I +D+ TW+A+E GL +++G+SNFN R ++ IL+ + +
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238
P QVECHPY Q +L+ C+++ + + AYS LGS + W DP+ PVLLE+PV+ ALA
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
Query: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298
+K+ R+PA I LR+Q+QR V+ + KS RI QN++VF+F + EEMK ++ LN+N RY
Sbjct: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
Query: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325
LT+D AG P YPF+D Y
Sbjct: 306 ----LTLD-----IFAGPPNYPFSDEY 323
>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 270 bits (691), Expect = 1e-72
Identities = 144/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)
Query: 5 CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
CV L+ G MP++G GT+ +E + KA AVK A+ G+ HID A +Y NE ++G A++
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
Query: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
+ G +V RE++F TSKLW+ H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 67 SKIADG-SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179
+ PK+ +G I +D+ TW+A+E GL +++G+SNFN R ++ IL+ + +
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238
P QVECHPY Q +L+ C+++ + + AYS LGS + W DP+ PVLLE+PV+ ALA
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
Query: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298
+K+ R+PA I LR+Q+QR V+ + KS RI QN++VF+F + EEMK ++ LN+N RY
Sbjct: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
Query: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325
LT+D AG P YPF+D Y
Sbjct: 306 ----LTLD-----IFAGPPNYPFSDEY 323
>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
Length = 326
Score = 270 bits (690), Expect = 1e-72
Identities = 145/331 (43%), Positives = 211/331 (63%), Gaps = 17/331 (5%)
Query: 2 AASCVLLHTGQKMPLIGLGTW---KSEP-GQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
A+ + L G +P+IGLGT+ KS P G +VK A+ GYRHID A IY NE E+G
Sbjct: 6 ASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVG 65
Query: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
EA++E + GK V RE++F KLW T H PE V P L +TL LQL+Y+DLY++ P A
Sbjct: 66 EAIREKIAEGK-VRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
F+ GD +P++ +G Y ++ TW+A+EA GLV++LG+SNFN RQ++ IL+
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 178 V--RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS-DRAWRDPDEPVLLEEPVV 234
+ +P QVECHPY Q +L+ CQ + +TAYSPLG+S + W + P LL++ ++
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244
Query: 235 LALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
+L ++Y ++ AQI+LR+ +QR V+ IPKS RI +N ++FDF+ + EEMK + ALNK
Sbjct: 245 NSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNK 304
Query: 295 NWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY 325
N R++ ++ D HP YPF+D Y
Sbjct: 305 NVRFVELLMWRD---------HPEYPFHDEY 326
>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
Length = 323
Score = 266 bits (681), Expect = 1e-71
Identities = 137/326 (42%), Positives = 210/326 (64%), Gaps = 16/326 (4%)
Query: 6 VLLHTGQKMPLIGLGTWKSEPGQVKAAV---KYALSVGYRHIDCAAIYGNEPEIGEALKE 62
V L+ G MP++G GT+ AV K A+ G+RHID A +Y NE ++G A++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 63 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122
+ G +V RE++F TSKLW T P+ V+PAL +L LQL+Y+DLYL+H+P A + G+
Sbjct: 68 KIADG-SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
Query: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--RP 180
P PK+ +G + +D+ TW+ +E GL +++G+SNFN RQ++ IL+ + +P
Sbjct: 127 TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKP 186
Query: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS-DRAWRDPDEPVLLEEPVVLALAE 239
QVECHPYL Q++L+ C+++ + + A+S LG+ + W DP+ PVLLE+PV+ ALA+
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAK 246
Query: 240 KYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
K+ ++PA I LR+Q+QR V+ + KS RI +NI+VF+F + E+MK L+ LN+N+RY+
Sbjct: 247 KHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYV 306
Query: 300 VPMLTVDGKRVPRDAGHPLYPFNDPY 325
V +D HP YPF+D Y
Sbjct: 307 VMDFLMD---------HPDYPFSDEY 323
>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
Length = 323
Score = 257 bits (656), Expect = 1e-68
Identities = 135/327 (41%), Positives = 205/327 (62%), Gaps = 16/327 (4%)
Query: 5 CVLLHTGQKMPLIGLGTWKS-EPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
CV L+ G MP++G GT+ E + KA K A+ G+RHID A +Y NE ++G A++
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
Query: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
+ G +V RE++F TSKLW+T H PE V PAL +L QL+Y+DLYL+H P + + G
Sbjct: 67 SKIADG-SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179
+ P + +G + +D TW+A+E GL +++G+SNFN RQ++ IL+ + +
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS-DRAWRDPDEPVLLEEPVVLALA 238
P QVECHPY +++L+ C+++ + + AYS LGS D+ W DP+ PVLLE+PV+ ALA
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALA 245
Query: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298
+K+ R+PA I LR+Q+QR V+ + KS RI QN++VF+F + E+MK ++ L++N Y
Sbjct: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHY 305
Query: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325
A HP YP++D Y
Sbjct: 306 F---------NSDSFASHPNYPYSDEY 323
>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
sapiens]
Length = 320
Score = 249 bits (637), Expect = 2e-66
Identities = 137/333 (41%), Positives = 192/333 (57%), Gaps = 37/333 (11%)
Query: 14 MPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPRE 73
+P +GL +WK+ PG+V AVK A+ GYRH DCA Y NE E+G ++ + G AV RE
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEG-AVRRE 62
Query: 74 ELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD----------- 122
+LF+ +KLW T H VE A RK+L L+L YLDLYL+HWP F+
Sbjct: 63 DLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELS 122
Query: 123 --------NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
P + + T + +TW+A+E LV GLV+ +G+SNFN Q++ +L+
Sbjct: 123 FCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLN 182
Query: 175 VASVR--PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEP 232
+R P Q+ECHPYL Q LI+ CQ+R + VTAY PLG S L++ P
Sbjct: 183 KPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVD------LIDNP 236
Query: 233 VVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNAL 292
V+ +A+++G+SPAQIL+R+Q+QR VI IP SITPS I +NI+VFDF + +M + +L
Sbjct: 237 VIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSL 296
Query: 293 NKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY 325
N+N R + P H YPF+ Y
Sbjct: 297 NRNLRLAM---------FPITKNHKDYPFHIEY 320
>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
Length = 139
Score = 108 bits (269), Expect = 8e-24
Identities = 54/114 (47%), Positives = 79/114 (69%), Gaps = 4/114 (3%)
Query: 5 CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
CV L+ G MP++G GT+ +E + KA AVK A+ G+ HID A +Y NE ++G A++
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
Query: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
+ G +V RE++F TSKLW+ H PE V PAL ++L +LQL+Y+DLYL+H+P
Sbjct: 67 SKIADG-SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
>gi|4504825 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 1 [Homo sapiens]
Length = 367
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 43/200 (21%)
Query: 10 TGQKMPLIGLGTWKSEPGQV-----KAAVKYALSVGYRHIDCAAIYGN---EPEIGEALK 61
+G ++ +GLGTW + GQ+ + + A G D A +Y E +G +K
Sbjct: 45 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIK 104
Query: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114
+ K R L +T+K+ W K E + L+ +L LQLEY+D+ +
Sbjct: 105 K-----KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 159
Query: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
P +P +T +ET +A+ ++ +G+ G S ++S +I + S
Sbjct: 160 P-------DP------------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYS 200
Query: 175 VAS----VRPAVLQVECHPY 190
VA P Q E H +
Sbjct: 201 VARQFNLTPPICEQAEYHMF 220
>gi|27436969 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 2 [Homo sapiens]
Length = 353
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 43/200 (21%)
Query: 10 TGQKMPLIGLGTWKSEPGQV-----KAAVKYALSVGYRHIDCAAIYGN---EPEIGEALK 61
+G ++ +GLGTW + GQ+ + + A G D A +Y E +G +K
Sbjct: 31 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIK 90
Query: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114
+ K R L +T+K+ W K E + L+ +L LQLEY+D+ +
Sbjct: 91 K-----KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 145
Query: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
P +P +T +ET +A+ ++ +G+ G S ++S +I + S
Sbjct: 146 P-------DP------------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYS 186
Query: 175 VAS----VRPAVLQVECHPY 190
VA P Q E H +
Sbjct: 187 VARQFNLTPPICEQAEYHMF 206
>gi|27436964 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 3 [Homo sapiens]
Length = 401
Score = 44.3 bits (103), Expect = 1e-04
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%)
Query: 10 TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61
+G ++ +GLGTW + GQ+ V A G D A +Y E +G +K
Sbjct: 79 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 138
Query: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114
+ K R L +T+KL W K E + L+ +L LQLEY+D+ +
Sbjct: 139 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 193
Query: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
P + +T +E +A+ ++ +G+ G S +++ +I + S
Sbjct: 194 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 234
Query: 175 VA----SVRPAVLQVECH 188
VA + P Q E H
Sbjct: 235 VARQFNMIPPVCEQAEYH 252
>gi|27436962 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 2 [Homo sapiens]
Length = 408
Score = 44.3 bits (103), Expect = 1e-04
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%)
Query: 10 TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61
+G ++ +GLGTW + GQ+ V A G D A +Y E +G +K
Sbjct: 86 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 145
Query: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114
+ K R L +T+KL W K E + L+ +L LQLEY+D+ +
Sbjct: 146 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 200
Query: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
P + +T +E +A+ ++ +G+ G S +++ +I + S
Sbjct: 201 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 241
Query: 175 VA----SVRPAVLQVECH 188
VA + P Q E H
Sbjct: 242 VARQFNMIPPVCEQAEYH 259
>gi|27436966 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 1 [Homo sapiens]
Length = 419
Score = 44.3 bits (103), Expect = 1e-04
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%)
Query: 10 TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61
+G ++ +GLGTW + GQ+ V A G D A +Y E +G +K
Sbjct: 97 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 156
Query: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114
+ K R L +T+KL W K E + L+ +L LQLEY+D+ +
Sbjct: 157 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 211
Query: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
P + +T +E +A+ ++ +G+ G S +++ +I + S
Sbjct: 212 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 252
Query: 175 VA----SVRPAVLQVECH 188
VA + P Q E H
Sbjct: 253 VARQFNMIPPVCEQAEYH 270
>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
Length = 359
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 30/192 (15%)
Query: 31 AAVKYALSVGYRHIDCAAIY--GNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKH-H 87
AAV+ L G+ +D A +Y G I L +G G R ++ + W+ K
Sbjct: 58 AAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC--RVKIATKANPWDGKSLK 115
Query: 88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
P+ V L +L LQ +DL+ +H P + G T +ET A
Sbjct: 116 PDSVRSQLETSLKRLQCPQVDLFYLHAP---DHG----------------TPVEETLHAC 156
Query: 148 EALVAKGLVQALGLSNFNSRQIDDILSVAS----VRPAVLQ--VECHPYLAQNELIAHCQ 201
+ L +G LGLSN+ S ++ +I ++ + P V Q + EL +
Sbjct: 157 QRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLR 216
Query: 202 ARGLEVTAYSPL 213
GL AY+PL
Sbjct: 217 HFGLRFYAYNPL 228
>gi|27436971 potassium voltage-gated channel, shaker-related
subfamily, beta member 3 [Homo sapiens]
Length = 404
Score = 37.0 bits (84), Expect = 0.024
Identities = 48/198 (24%), Positives = 79/198 (39%), Gaps = 43/198 (21%)
Query: 10 TGQKMPLIGLGTWKSEPGQVK-AAVKYALSVGYRH----IDCAAIYG---NEPEIGEALK 61
+G ++ +GLGTW + Q+ + L+V Y H D A +Y E +G LK
Sbjct: 86 SGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILK 145
Query: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114
K R +T+K+ W + E + LR +L LQL Y+D+ +
Sbjct: 146 -----SKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFAN- 199
Query: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174
R D P +E +A+ ++ +GL G S + + +I + S
Sbjct: 200 -----RSDPNCP-------------MEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYS 241
Query: 175 VAS----VRPAVLQVECH 188
+A + P Q E H
Sbjct: 242 MARQFNLIPPVCEQAEHH 259
>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
sapiens]
Length = 331
Score = 36.6 bits (83), Expect = 0.031
Identities = 46/192 (23%), Positives = 76/192 (39%), Gaps = 30/192 (15%)
Query: 31 AAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG--PGKAVPREELFVTSKLW-NTKHH 87
A + L G+ ID A +Y + E + +G G + R ++ + W
Sbjct: 30 AVTRAFLERGHTEIDTAFLYSDGQS--ETILGGLGLRMGSSDCRVKIATKANPWIGNSLK 87
Query: 88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
P+ V L +L LQ +DL+ +H P D+ P +ET +A
Sbjct: 88 PDSVRSQLETSLKRLQCPUVDLFYLHAP------DHSAP-------------VEETLRAC 128
Query: 148 EALVAKGLVQALGLSNFNSRQIDDILSVAS----VRPAVLQ--VECHPYLAQNELIAHCQ 201
L +G LGLSN+ + ++ +I ++ + P V Q + EL +
Sbjct: 129 HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPCLR 188
Query: 202 ARGLEVTAYSPL 213
GL AY+PL
Sbjct: 189 HFGLRFYAYNPL 200
>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
sapiens]
Length = 249
Score = 35.0 bits (79), Expect = 0.091
Identities = 47/206 (22%), Positives = 77/206 (37%), Gaps = 34/206 (16%)
Query: 31 AAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG--PGKAVPREELFVTSKLW-NTKHH 87
A + L G+ ID A +Y + E + +G G + R ++ + W
Sbjct: 30 AVTRAFLERGHTEIDTAFLYSDGQS--ETILGGLGLRMGSSDCRVKIATKANPWIGNSLK 87
Query: 88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
P+ V L +L LQ +DL+ +H P D+ P +ET +A
Sbjct: 88 PDSVRSQLETSLKRLQCPUVDLFYLHAP------DHSAP-------------VEETLRAC 128
Query: 148 EALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEV 207
L +G LGLSN+ + ++ +I ++ +L + L L HC
Sbjct: 129 HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPT-VYQLLEGAPLRGHCPGGE--- 184
Query: 208 TAYSPLGSSDRAWRDPDEPVLLEEPV 233
G + R WR + L PV
Sbjct: 185 ------GPAGRVWRQRSQHDLGRPPV 204
>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
Length = 331
Score = 33.5 bits (75), Expect = 0.26
Identities = 48/199 (24%), Positives = 75/199 (37%), Gaps = 44/199 (22%)
Query: 31 AAVKYALSVGYRHIDCAAIY--GNEPEIGEALKEDVGPG--------KAVPREELFVTSK 80
A + L G+ ID A +Y G I L +G KA+P
Sbjct: 30 AVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--------- 80
Query: 81 LWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHY 140
L+ P+ + L +L LQ +DL+ +H P ST
Sbjct: 81 LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-------------------HSTPV 121
Query: 141 KETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS----VRPAVLQVECHPYLAQ--N 194
+ET +A L +G LGLSN+ + ++ +I ++ + P V Q + Q
Sbjct: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
Query: 195 ELIAHCQARGLEVTAYSPL 213
EL + GL A++PL
Sbjct: 182 ELFPCLRHFGLRFYAFNPL 200
>gi|4504011 glutamate-cysteine ligase regulatory protein [Homo
sapiens]
Length = 274
Score = 31.2 bits (69), Expect = 1.3
Identities = 15/47 (31%), Positives = 25/47 (53%)
Query: 139 HYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQV 185
H + W+ LE LV + A+G S+ + Q++ + A V+P QV
Sbjct: 142 HLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E
subunit [Homo sapiens]
Length = 2270
Score = 30.4 bits (67), Expect = 2.2
Identities = 22/89 (24%), Positives = 42/89 (47%), Gaps = 5/89 (5%)
Query: 92 EPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALV 151
+P L + + L Y D Y+ + FE + G I D +++++ W L+ +V
Sbjct: 1174 DPVLTNSERNKVLRYFD-YVFTGVFTFEMVIKMIDQ---GLILQDGSYFRDLWNILDFVV 1229
Query: 152 AKGLVQALGLSN-FNSRQIDDILSVASVR 179
G + A L+N + + DI ++ S+R
Sbjct: 1230 VVGALVAFALANALGTNKGRDIKTIKSLR 1258
>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
sapiens]
Length = 987
Score = 30.0 bits (66), Expect = 2.9
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 213 LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRW 252
L +S RAW+ + + + + ALA +YG S LL+W
Sbjct: 851 LSASTRAWKPQSKLSVERKDPLAALAREYGGSKRNALLKW 890
>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
sapiens]
Length = 1068
Score = 30.0 bits (66), Expect = 2.9
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 213 LGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRW 252
L +S RAW+ + + + + ALA +YG S LL+W
Sbjct: 932 LSASTRAWKPQSKLSVERKDPLAALAREYGGSKRNALLKW 971
>gi|24308241 zinc finger and BTB domain containing 2 [Homo sapiens]
Length = 514
Score = 28.9 bits (63), Expect = 6.5
Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 157 QALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH-CQARGLEVTAYSP--- 212
Q L L F D + V + +P + + NE++ H CQ + +V A
Sbjct: 424 QTLELCTFEEGSQMDNMLVQTNKPYKCNLCDKTFSTPNEVVKHSCQNQNSDVFALDEGRS 483
Query: 213 --LGSSDRAWRDPDEPVL 228
LGS D +PD PVL
Sbjct: 484 ILLGSGDSEVTEPDHPVL 501
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,452,638
Number of Sequences: 37866
Number of extensions: 610811
Number of successful extensions: 1383
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1314
Number of HSP's gapped (non-prelim): 28
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.