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Search of human proteins with 51093836
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo
sapiens]
(1012 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] 2012 0.0
gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens] 1629 0.0
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 66 2e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 64 5e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 62 2e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 62 3e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 62 3e-09
gi|148746195 trichohyalin [Homo sapiens] 62 3e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 61 5e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 61 5e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 6e-09
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 59 3e-08
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 59 3e-08
gi|4506751 restin isoform a [Homo sapiens] 58 4e-08
gi|221219020 NYD-SP11 protein [Homo sapiens] 57 7e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 57 7e-08
gi|118498356 kinectin 1 isoform a [Homo sapiens] 57 9e-08
gi|33620775 kinectin 1 isoform a [Homo sapiens] 57 9e-08
gi|71061468 centromere protein E [Homo sapiens] 57 9e-08
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 57 9e-08
gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s... 57 9e-08
gi|157785668 coiled-coil domain containing 39 [Homo sapiens] 57 9e-08
gi|118498368 kinectin 1 isoform c [Homo sapiens] 57 1e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 56 1e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 56 1e-07
gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 55 3e-07
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 55 3e-07
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 55 4e-07
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 55 4e-07
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 55 4e-07
>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
Length = 1012
Score = 2012 bits (5213), Expect = 0.0
Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)
Query: 1 MSLPKTPSTPLNSTSTSESKKLKVSVAKEGTRGLPELKEKKNMVDRSKLLPTSLQNEFIP 60
MSLPKTPSTPLNSTSTSESKKLKVSVAKEGTRGLPELKEKKNMVDRSKLLPTSLQNEFIP
Sbjct: 1 MSLPKTPSTPLNSTSTSESKKLKVSVAKEGTRGLPELKEKKNMVDRSKLLPTSLQNEFIP 60
Query: 61 KEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSL 120
KEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSL
Sbjct: 61 KEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSL 120
Query: 121 TGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHI 180
TGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHI
Sbjct: 121 TGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHI 180
Query: 181 VSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQ 240
VSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQ
Sbjct: 181 VSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQ 240
Query: 241 EYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIAR 300
EYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIAR
Sbjct: 241 EYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIAR 300
Query: 301 QMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQ 360
QMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQ
Sbjct: 301 QMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQ 360
Query: 361 ALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILA 420
ALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILA
Sbjct: 361 ALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILA 420
Query: 421 RRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSET 480
RRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSET
Sbjct: 421 RRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSET 480
Query: 481 LKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYD 540
LKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYD
Sbjct: 481 LKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYD 540
Query: 541 TLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNG 600
TLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNG
Sbjct: 541 TLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNG 600
Query: 601 YSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHI 660
YSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHI
Sbjct: 601 YSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHI 660
Query: 661 DVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNF 720
DVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNF
Sbjct: 661 DVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNF 720
Query: 721 TDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTN 780
TDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTN
Sbjct: 721 TDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTN 780
Query: 781 SHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIE 840
SHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIE
Sbjct: 781 SHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIE 840
Query: 841 PEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETD 900
PEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETD
Sbjct: 841 PEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETD 900
Query: 901 VLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKN 960
VLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKN
Sbjct: 901 VLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKN 960
Query: 961 KDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKKGH 1012
KDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKKGH
Sbjct: 961 KDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKKGH 1012
>gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]
Length = 938
Score = 1629 bits (4219), Expect = 0.0
Identities = 854/1018 (83%), Positives = 882/1018 (86%), Gaps = 86/1018 (8%)
Query: 1 MSLPKTPSTPLNSTSTSESKKLKVSVAKEGTRGLPELKEKKNMVDRSKLLPTSLQNEFIP 60
MSLPKTPSTPLNSTSTSESKKLKVSVAKEGTRGLPELKEKKNMVDRSKLLPTSLQNEFIP
Sbjct: 1 MSLPKTPSTPLNSTSTSESKKLKVSVAKEGTRGLPELKEKKNMVDRSKLLPTSLQNEFIP 60
Query: 61 KEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSL 120
KEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSL
Sbjct: 61 KEVLLSLTYAANAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSL 120
Query: 121 TGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHI 180
TGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHI
Sbjct: 121 TGAGRDISFLYDVTYAKGQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHI 180
Query: 181 VSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQ 240
VSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQ
Sbjct: 181 VSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQ 240
Query: 241 EYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIAR 300
EYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIAR
Sbjct: 241 EYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIAR 300
Query: 301 QMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQ 360
QMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQ
Sbjct: 301 QMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQ 360
Query: 361 ALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILA 420
ALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILA
Sbjct: 361 ALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILA 420
Query: 421 RRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSET 480
RRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSET
Sbjct: 421 RRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSET 480
Query: 481 LKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYD 540
LKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYD
Sbjct: 481 LKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYD 540
Query: 541 TLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNG 600
TLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNG
Sbjct: 541 TLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNG 600
Query: 601 YSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHI 660
YSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHI
Sbjct: 601 YSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHI 660
Query: 661 DVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNF 720
DVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNF
Sbjct: 661 DVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNF 720
Query: 721 TDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTN 780
TDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTN
Sbjct: 721 TDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTN 780
Query: 781 SHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLL----EEEAV- 835
SHKNATEDLYEVDKLK+ T E E+L+ E+E V
Sbjct: 781 SHKNATEDLYEVDKLKQPS----------------------TSTEKEKLIRFIGEDENVH 818
Query: 836 -KEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSK 894
K E ++ S++E ++ T +K + + E++ K
Sbjct: 819 SKPLFETDVLSSWRESAKQ---------------------GTLAQKYLEAMAVIEHMQEK 857
Query: 895 PLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLH 954
L E + A+Q +K+ +A + H K ++E + ++ ++ E
Sbjct: 858 -LLEVE------NRARQA--EEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKE--- 905
Query: 955 HTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKKGH 1012
NQDEREVKEEEEQQEEEEVRSAENSSKSPKKGH
Sbjct: 906 -------------------------NQDEREVKEEEEQQEEEEVRSAENSSKSPKKGH 938
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 65.9 bits (159), Expect = 2e-10
Identities = 46/192 (23%), Positives = 95/192 (49%), Gaps = 18/192 (9%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEEN-----KERAEEQPSTSTE 877
+ + E++ E+E ++E +E +E EE +++ K++E+ KE+ EQ +
Sbjct: 440 WRQEEKIHEQEKIRE------EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 878 KEKLIRFIGEDENVHSKP-LFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVE 936
+EK+ R ++E +H + WR+ K +K E I +E + E E
Sbjct: 494 EEKVWR---QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQE 550
Query: 937 NRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKEN--QDEREVKEEEEQQE 994
+ + EEK ++ EK+ K ++ EE + +++ +E++E + E +++E+EE +
Sbjct: 551 EKMGEQEEKMQEQ-EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ 609
Query: 995 EEEVRSAENSSK 1006
E+E + E K
Sbjct: 610 EQEEKMWEQEEK 621
Score = 65.1 bits (157), Expect = 3e-10
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 10/190 (5%)
Query: 824 EEIERLLEEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEE----QPSTSTE 877
+E + +EE ++E E E ++ EE+ E K++EE K + +E Q E
Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473
Query: 878 KEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVEN 937
+E++ R + E +H + WR+ K +K E + +EK+ E E
Sbjct: 474 QEEIWR---QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE 530
Query: 938 RARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRK-ESKEEKENQDEREVKEEEEQQEEE 996
+ R+ EEK + E + K + EE + K +EEK + E +++E++E+ E+
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 997 EVRSAENSSK 1006
E + E K
Sbjct: 591 EEKIWEQEEK 600
Score = 60.8 bits (146), Expect = 6e-09
Identities = 50/217 (23%), Positives = 101/217 (46%), Gaps = 22/217 (10%)
Query: 814 KGRKITLLTYEEIERLLE-EEAVKEFIEPEIDESFKEDEEESKEDRKLQEEN------KE 866
K R++ + +E+ E++ E EE + E + E +++EE+ +E K QE+ +E
Sbjct: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 423
Query: 867 RAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSS-----WRESAK-----QGTLAQ 916
+ EQ E+EK + ++E +H + + WR+ K + +
Sbjct: 424 KIREQEEKIREQEK--KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 481
Query: 917 KYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKE 976
+ + I +EK+ E + EEK + EK+ K ++ EE + ++ +E
Sbjct: 482 EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
Query: 977 EKENQDEREVK---EEEEQQEEEEVRSAENSSKSPKK 1010
++E E+E K +EE+ QE+E++R E + ++
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
Score = 57.8 bits (138), Expect = 5e-08
Identities = 43/181 (23%), Positives = 85/181 (46%), Gaps = 29/181 (16%)
Query: 823 YEEIERLLEEEAVKEFIEPEI---DESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKE 879
+++ E++ E+E E +I +E +E EE+ +E ++ +E +E+ EQ E+E
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Query: 880 KLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA 939
K+ R ++E + + +K E I +EK+ E E +
Sbjct: 565 KMRR---QEEKIREQE--------------------EKIREQKEKIREQEEKIWEQEEKI 601
Query: 940 RQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVK---EEEEQQEEE 996
R+ EE ++ EK+ K + EE + ++ + ++E E+EV+ +EE+ QE +
Sbjct: 602 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Query: 997 E 997
E
Sbjct: 662 E 662
Score = 57.0 bits (136), Expect = 9e-08
Identities = 40/192 (20%), Positives = 95/192 (49%), Gaps = 19/192 (9%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
EEI R E+ +E I + ++ ++++E+ ++ K++E+ ++ ++ ++EK+
Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE 534
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
++E + + +++ E K G +K ++ + +EK+ E E + R+ +
Sbjct: 535 ---QEEKIRE----QEEMMQEQEE--KMGEQEEK-MQEQEKMRRQEEKIREQEEKIREQK 584
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKE---------SKEEKENQDEREVKEEEEQQE 994
EK + EK+ K ++ EE++ ++ +EEK + E +++ +EE+
Sbjct: 585 EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 644
Query: 995 EEEVRSAENSSK 1006
E+EVR + K
Sbjct: 645 EQEVRLRQQEEK 656
Score = 55.8 bits (133), Expect = 2e-07
Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 7/179 (3%)
Query: 823 YEEIERLLE-EEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKE 879
+ + E++ E EE ++E E E +E +E EE+ + ++ E +E+ Q EKE
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362
Query: 880 KLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA 939
+ +R + +E + K ++ E K +K E + E QEK E E +
Sbjct: 363 EKMRRL--EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE--QEKRQEQEAKM 418
Query: 940 RQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEV 998
+ EEK + EK+ K EE + K +EEK + E ++EE+ +E+EE+
Sbjct: 419 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Score = 48.5 bits (114), Expect = 3e-05
Identities = 30/133 (22%), Positives = 67/133 (50%), Gaps = 5/133 (3%)
Query: 824 EEIERLLEEEAVKEFIEPEI---DESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEK 880
E+ E++ E+E + + E ++ +E +E E+ +++ K++E+ ++ E++ ++EK
Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEK 593
Query: 881 LIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRAR 940
+ + E++ + + + W + K +K E + +EK+ E E R R
Sbjct: 594 I--WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 651
Query: 941 QAEEKFEDAYEKL 953
Q EEK ++ E L
Sbjct: 652 QQEEKMQEHQEHL 664
Score = 48.1 bits (113), Expect = 4e-05
Identities = 69/302 (22%), Positives = 122/302 (40%), Gaps = 49/302 (16%)
Query: 741 VARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECY 800
V +LE +A +L +L+ + + + +A+A K + + E E D L E Y
Sbjct: 153 VKQLEGEARDLISRLHDSWKFAGELEQAL-SAVATQKK-KADRYIEELTKERDALSLELY 210
Query: 801 EWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESK---ED 857
NT + K K+ E+L E+ K I+ + E K E +K
Sbjct: 211 R--NTITDEELKEKNAKLQ-------EKLQLVESEKSEIQLNVKE-LKRKLERAKLLLPQ 260
Query: 858 RKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQK 917
++LQ E +E S S + + + +EN L + WR+ K +K
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQV-----EENELWNRLNQQQEEKMWRQEEKIQEWEEK 315
Query: 918 YLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLI------------------- 958
E I +EK+ E E + R+ EE + EK+
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK 375
Query: 959 --KNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQE--------EEEVRSAENSSKSP 1008
K ++LEE + K ++E++ Q+E +++E+E++QE EE++R E +
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435
Query: 1009 KK 1010
+K
Sbjct: 436 EK 437
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 64.3 bits (155), Expect = 5e-10
Identities = 46/185 (24%), Positives = 89/185 (48%), Gaps = 14/185 (7%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
E+ E++ E+E + + E +E E EE+ E + +E +E+ Q E+EK IR
Sbjct: 394 EQEEKIREQEEMMQ----EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
++E + + +++ E K G K E A ++ +EK+ E + R+ E
Sbjct: 450 --EQEEKIRE----QEEMMQEQEE--KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKE--SKEEKENQDEREVKEEEEQQEEEEVRSA 1001
+K + EK+ ++ EE + ++ +EEK + E +++ +EE+ E+EVR
Sbjct: 502 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLR 561
Query: 1002 ENSSK 1006
+ K
Sbjct: 562 QQEEK 566
Score = 63.2 bits (152), Expect = 1e-09
Identities = 45/195 (23%), Positives = 88/195 (45%), Gaps = 24/195 (12%)
Query: 831 EEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGE- 887
+EE ++E E E +E +E EE+ + ++ E +E+ Q EKE+ IR + E
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 888 ----------------DENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEK 931
+E + + + WR+ K +K E +++ +EK
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 932 LLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEE 991
+ E E + + EE+ ++ EK+ K ++ E+ + +EEK + E ++E+EE
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI-----REQEEKIREQEEMMQEQEE 467
Query: 992 QQEEEEVRSAENSSK 1006
+ E+E + E +K
Sbjct: 468 KMGEQEGKMCEQEAK 482
Score = 57.0 bits (136), Expect = 9e-08
Identities = 46/203 (22%), Positives = 97/203 (47%), Gaps = 18/203 (8%)
Query: 814 KGRKITLLTYEEIERLLEEEAV---KEFIEPEIDESFKEDEEESKEDRKLQEENKERAEE 870
K R+ + +E+ E++ +E + KE E++E E E+ +++ K QEE E+ E
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE--EKIRE 374
Query: 871 QPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQE 930
Q ++ K+ R + K + +++ E K G +K E ++ +E
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE--KMGEQEEKMWEQEEEMQEQEE 432
Query: 931 KLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELV---------MTSRKESKEEKENQ 981
K+ E + R+ E+K + EK+ ++ EE + ++ + +EEK +
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 982 DEREVKEEEE--QQEEEEVRSAE 1002
E +++E+E+ +++EE++R E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQE 515
Score = 56.6 bits (135), Expect = 1e-07
Identities = 47/187 (25%), Positives = 87/187 (46%), Gaps = 15/187 (8%)
Query: 831 EEEAVKEFIEPEIDESFKEDEEESK--EDRKLQEENKERAEE-----QPSTSTEKEKLIR 883
+EE ++E +E ++ E K E+E K E+ K++E+ K + +E Q E+E+ IR
Sbjct: 342 KEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
E + + E + W + + +K I ++K+ E E + R+ E
Sbjct: 401 EQEEMMQEQEEKMGEQEE-KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESK----EEKENQDEREVKEEEEQQEEEEVR 999
E ++ EK+ + K E+ +E K EEK + E++++E+EE+ E+E
Sbjct: 460 EMMQEQEEKMGEQ--EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517
Query: 1000 SAENSSK 1006
E K
Sbjct: 518 MQEQEEK 524
Score = 55.5 bits (132), Expect = 3e-07
Identities = 70/312 (22%), Positives = 132/312 (42%), Gaps = 37/312 (11%)
Query: 721 TDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTN 780
T C +E+ A R EL+A T ++ C+ MAL S +
Sbjct: 88 TSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILT--------CQKTELQMALYYSQH 139
Query: 781 SHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIE 840
+ K + ++ + +++ LS + +K Y IE L +E ++ +
Sbjct: 140 AVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRY--IEELTKE---RDALS 194
Query: 841 PEIDESFKEDEEESKEDRKLQEE----NKERAEEQPSTSTEKEKLIR------------- 883
E+ + DEE +++ KLQE+ E++E Q + K KL R
Sbjct: 195 LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAE 254
Query: 884 --FIGED-ENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRAR 940
+G++ ++V +K + + W +Q +K I+ +EK+ E E + R
Sbjct: 255 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQE--EKMWRQEEKIQEREEKIQEQEEKIR 312
Query: 941 QAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESK--EEKENQDEREVKEEEEQQEEEEV 998
+ EEK E + K + EE++ ++ + EEK ++ E+ ++EE++QEEE++
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 372
Query: 999 RSAENSSKSPKK 1010
R E + K
Sbjct: 373 REQEKRQEQEAK 384
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 62.4 bits (150), Expect = 2e-09
Identities = 45/183 (24%), Positives = 87/183 (47%), Gaps = 13/183 (7%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
E+ E++ E+E E +I E K EEE +++++ +E+ EQ +KEK+
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
++E + + WR+ K +K E + +EK+ E E + R+ E
Sbjct: 548 ---QEEKIRKQEE------KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 944 EKFEDAYEKLHHTLIKNKDLEELV--MTSRKESKEEKENQDEREVKEEEE--QQEEEEVR 999
EK + E K + EE + + + +EEK + E +++E+E+ +++EE++R
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658
Query: 1000 SAE 1002
E
Sbjct: 659 EQE 661
Score = 61.6 bits (148), Expect = 4e-09
Identities = 47/200 (23%), Positives = 93/200 (46%), Gaps = 10/200 (5%)
Query: 814 KGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPS 873
K R+ + +E+ E++ E E E ++ K EEE +++ ++E + + Q
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 874 TSTEKEKLIR-----FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHM 928
E+E+ IR ++E +H + + R+ ++ ++ + I
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREE---EKRQEQEEMWRQEEKIREQEEIWRQ 541
Query: 929 QEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKE--SKEEKENQDEREV 986
+EK+ E E + R+ EEK EK+H K ++ EE V ++ +EEK + E ++
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI 601
Query: 987 KEEEEQQEEEEVRSAENSSK 1006
+E+EE +E+E + E K
Sbjct: 602 REQEEMTQEQEEKMGEQEEK 621
Score = 61.6 bits (148), Expect = 4e-09
Identities = 49/193 (25%), Positives = 88/193 (45%), Gaps = 25/193 (12%)
Query: 824 EEIERLLEEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKL 881
+E + +EE ++E E E +E EE+ E K++EE K + +E+ EK
Sbjct: 475 QEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK--- 531
Query: 882 IRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQ 941
I E E + WR+ K +K + + +EK+ + E + R+
Sbjct: 532 ---IREQEEI-------------WRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIRE 575
Query: 942 AEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVK----EEEEQQEEEE 997
EEK EK+ K ++ EE + + ++E++E E+E K EE+ Q++EE+
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK 635
Query: 998 VRSAENSSKSPKK 1010
+R E + +K
Sbjct: 636 MRRQEEKIREQEK 648
Score = 61.6 bits (148), Expect = 4e-09
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 6/187 (3%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLI 882
+ + E++ E+E ++E + + E EE+ +E ++ + ++ E++ ++EK+
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 883 RFIGEDENVH-SKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQ 941
R ++E +H + WR+ K +K E I +E E E + +
Sbjct: 561 R---QEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 942 AEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDERE--VKEEEEQQEEEEVR 999
EEK + EK+ K + EE + K+ +E++E E+E ++E+EE+ E+E +
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Query: 1000 SAENSSK 1006
E K
Sbjct: 678 MCEQEEK 684
Score = 61.6 bits (148), Expect = 4e-09
Identities = 43/189 (22%), Positives = 95/189 (50%), Gaps = 7/189 (3%)
Query: 823 YEEIERLLEEEAV---KEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKE 879
+ + E++ E+E + KE I + ++ K++E+ +++ K+ ++ +E+ EQ +E
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ-EEKIREQEEKVWRQE 584
Query: 880 KLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA 939
+ IR E + + E + ++ +E K G +K E ++ +EK+ E +
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEE-KMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 940 RQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKE--SKEEKENQDEREVKEEEEQQEEEE 997
R+ E+K + EK+ ++ EE + ++ +EEK + E +++ +EE+ E+E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Query: 998 VRSAENSSK 1006
VR + K
Sbjct: 704 VRLRQQEEK 712
Score = 56.2 bits (134), Expect = 1e-07
Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 7/179 (3%)
Query: 823 YEEIERLLE-EEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKE 879
+ + E++ E EE ++E E E +E +E EE+ + ++ E +E+ Q EKE
Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 423
Query: 880 KLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA 939
+ +R ++E + K ++ E K +K E + E QEK E E +
Sbjct: 424 EKMR--RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE--QEKRQEQEAKM 479
Query: 940 RQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEV 998
+ EEK + EK+ K EE + K +EEK + E ++EE+ +E+EE+
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Score = 52.0 bits (123), Expect = 3e-06
Identities = 71/282 (25%), Positives = 118/282 (41%), Gaps = 29/282 (10%)
Query: 741 VARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECY 800
V +LE +A +L +L+ + + + +A+A K + + E E D L E Y
Sbjct: 214 VKQLEGEARDLISRLHDSWKFAGELEQAL-SAVATQKK-KADRYIEELTKERDALSLELY 271
Query: 801 EWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESK---ED 857
NT + K K+ E+L E+ K I+ + E K E +K
Sbjct: 272 R--NTITDEELKEKNAKLQ-------EKLQLVESEKSEIQLNVKE-LKRKLERAKLLLPQ 321
Query: 858 RKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQK 917
++LQ E +E S S + + + +EN L + WR+ K +K
Sbjct: 322 QQLQAEADHLGKELQSVSAKLQAQV-----EENELWNRLNQQQEEKMWRQEEKIQEWEEK 376
Query: 918 YLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELV-----MTSRK 972
E I +EK+ E E + R+ EE + EK+ + EE + M K
Sbjct: 377 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 436
Query: 973 ESK----EEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
E K EEK ++ E+ ++EE++QEEE++R E + K
Sbjct: 437 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478
Score = 51.6 bits (122), Expect = 4e-06
Identities = 40/187 (21%), Positives = 89/187 (47%), Gaps = 22/187 (11%)
Query: 814 KGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPS 873
K RK + + E++ ++E E I + ++ ++++E+ +++ K++E+ ++ E++
Sbjct: 551 KIRKQEEKMWRQEEKMHDQE---EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607
Query: 874 TSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLL 933
T ++EK+ GE E + K +K I ++K+
Sbjct: 608 TQEQEEKM----GEQEE------------KMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Query: 934 EVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVK---EEE 990
E E + R+ EE ++ EK+ K + EE + ++ + ++E E+EV+ +EE
Sbjct: 652 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711
Query: 991 EQQEEEE 997
+ QE +E
Sbjct: 712 KMQEHQE 718
Score = 50.4 bits (119), Expect = 8e-06
Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 5/130 (3%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
E+ E++ E+E + + E +E E EE+ E + +E +E+ Q E+EK IR
Sbjct: 596 EQEEKIREQEEMTQ----EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
E++ + + + W + K +K E + +EK+ E E R RQ E
Sbjct: 652 E-QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 710
Query: 944 EKFEDAYEKL 953
EK ++ E L
Sbjct: 711 EKMQEHQEHL 720
Score = 49.7 bits (117), Expect = 1e-05
Identities = 51/203 (25%), Positives = 93/203 (45%), Gaps = 28/203 (13%)
Query: 824 EEIERLLE-EEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEK 880
E+ E++ E EE ++E E +E E EE+ + ++ E +E+ Q EKE+
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 881 LIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRAR 940
IR + +E +H + R+ ++ +K E A + +EK+ E E + R
Sbjct: 439 KIREL--EEKMHEQEKIREQ--EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 941 QAEEKFEDAYEKLHHTLI-----KNKDLEELVMTSRK--ESKE-----EKENQDEREVKE 988
+ EEK EK+H K ++ EE+ K E +E EK ++ E ++++
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 989 EEEQQ---------EEEEVRSAE 1002
+EE+ +EE++R E
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQE 577
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.0 bits (149), Expect = 3e-09
Identities = 45/179 (25%), Positives = 90/179 (50%), Gaps = 14/179 (7%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKE--RAEEQPSTSTEKEK 880
+ + E++ E+E E I + ++ ++++E+ ++D K+QE+ +E R EE+ EK +
Sbjct: 349 WRQEEKIREQE---EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 881 LIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRAR 940
+ E + WR+ +K E +++ +EKL EVE + +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQE-------EKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 941 QAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKE--NQDEREVKEEEEQQEEEE 997
+ EEK ++ EK+ K ++ EE K K+E++ Q+E+ ++EE+ E+EE
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
Score = 57.4 bits (137), Expect = 7e-08
Identities = 56/239 (23%), Positives = 115/239 (48%), Gaps = 30/239 (12%)
Query: 791 EVDKLKKECYEWINTCSCLLSNIKGRKI-TLLTYEEIERLL-EEEAVKEFIEPEIDESFK 848
E D+L KE + + L + ++ ++ LL ++ E++ +EE ++E E ++ K
Sbjct: 263 EADRLGKELQ---SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319
Query: 849 EDEEESKEDRKLQE--ENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWR 906
E+E K R+ ++ E +E+ EQ +E+ IR ++E + + WR
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR--EQEEKIREQEE------KMWR 371
Query: 907 ESAKQGTLAQKYLEAMAVI-----------EHMQEKLLEVENRARQAEEKFEDAYEKLHH 955
+ K +K E + E QEK+ E + R+ +EK + E++
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 956 TLIKNKDLEELVMTSRKESK--EEKENQDEREVKEEEE--QQEEEEVRSAENSSKSPKK 1010
K ++LEE++ ++ + EEK ++E +++E+EE Q++EE+++ E + +K
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Score = 54.3 bits (129), Expect = 6e-07
Identities = 42/188 (22%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
+E E +EE ++E E ++ ++++++ ++D K++E+ +E ++ +E +
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQD 445
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
+ V K E + + E ++ ++ ++ QEKLL+ E + + E
Sbjct: 446 QEEKLREVEEKMQEEEEKMQEQEEKIQR---QEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAEN 1003
EK EK+ K ++ EE + + +EEK + E + ++EE+ +E+EVR E
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEE-----KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557
Query: 1004 SSKSPKKG 1011
+ K G
Sbjct: 558 EERLGKLG 565
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.0 bits (149), Expect = 3e-09
Identities = 45/179 (25%), Positives = 90/179 (50%), Gaps = 14/179 (7%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKE--RAEEQPSTSTEKEK 880
+ + E++ E+E E I + ++ ++++E+ ++D K+QE+ +E R EE+ EK +
Sbjct: 349 WRQEEKIREQE---EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 881 LIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRAR 940
+ E + WR+ +K E +++ +EKL EVE + +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQE-------EKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 941 QAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKE--NQDEREVKEEEEQQEEEE 997
+ EEK ++ EK+ K ++ EE K K+E++ Q+E+ ++EE+ E+EE
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
Score = 57.4 bits (137), Expect = 7e-08
Identities = 56/239 (23%), Positives = 115/239 (48%), Gaps = 30/239 (12%)
Query: 791 EVDKLKKECYEWINTCSCLLSNIKGRKI-TLLTYEEIERLL-EEEAVKEFIEPEIDESFK 848
E D+L KE + + L + ++ ++ LL ++ E++ +EE ++E E ++ K
Sbjct: 263 EADRLGKELQ---SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319
Query: 849 EDEEESKEDRKLQE--ENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWR 906
E+E K R+ ++ E +E+ EQ +E+ IR ++E + + WR
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR--EQEEKIREQEE------KMWR 371
Query: 907 ESAKQGTLAQKYLEAMAVI-----------EHMQEKLLEVENRARQAEEKFEDAYEKLHH 955
+ K +K E + E QEK+ E + R+ +EK + E++
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 956 TLIKNKDLEELVMTSRKESK--EEKENQDEREVKEEEE--QQEEEEVRSAENSSKSPKK 1010
K ++LEE++ ++ + EEK ++E +++E+EE Q++EE+++ E + +K
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Score = 54.3 bits (129), Expect = 6e-07
Identities = 42/188 (22%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
+E E +EE ++E E ++ ++++++ ++D K++E+ +E ++ +E +
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQD 445
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
+ V K E + + E ++ ++ ++ QEKLL+ E + + E
Sbjct: 446 QEEKLREVEEKMQEEEEKMQEQEEKIQR---QEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAEN 1003
EK EK+ K ++ EE + + +EEK + E + ++EE+ +E+EVR E
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEE-----KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557
Query: 1004 SSKSPKKG 1011
+ K G
Sbjct: 558 EERLGKLG 565
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 62.0 bits (149), Expect = 3e-09
Identities = 54/215 (25%), Positives = 102/215 (47%), Gaps = 25/215 (11%)
Query: 814 KGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDR--KLQEENKE----- 866
+GRK EE +RL +E ++F++ E +E E++ ++DR K +EE ++
Sbjct: 1372 QGRKFL----EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE 1427
Query: 867 -----RAEEQPSTSTEKEKLIRFIGEDENV----HSKPLFETDVLSSWRESA-KQGTLAQ 916
R EEQ E+E+ +F+ E++ + H K E +L E + +
Sbjct: 1428 RDRKFREEEQQVRRQERER--KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 917 KYLEAMAVIEHMQE--KLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKES 974
K+LE + + K E E R+++ E KF + ++LH + K L+E R+E
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 975 KEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPK 1009
+++ +R+ +EEE+ ++E E + + K
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Score = 57.0 bits (136), Expect = 9e-08
Identities = 52/197 (26%), Positives = 93/197 (47%), Gaps = 16/197 (8%)
Query: 816 RKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTS 875
RK L EE E L EE K + E + ++E+E+ +E+ +L E +E+ Q
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQ-EQERQYREEEQLQQEEEQLLREEREKRRRQ---- 954
Query: 876 TEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEV 935
E+E+ R +D+ + K E +L E ++ +KY E ++ +E+LL
Sbjct: 955 -ERERQYR---KDKKLQQK---EEQLLGEEPEKRRRQEREKKYREEEE-LQQEEEQLLRE 1006
Query: 936 ENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ--Q 993
E R+ +E +E Y K + + L R+ + E++ ++E E+++EEEQ
Sbjct: 1007 EREKRRRQE-WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 994 EEEEVRSAENSSKSPKK 1010
EE E R + + +K
Sbjct: 1066 EERETRRRQELERQYRK 1082
Score = 55.8 bits (133), Expect = 2e-07
Identities = 49/184 (26%), Positives = 94/184 (51%), Gaps = 22/184 (11%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
+E E+LL EE K + + K+DE + +E++ L+EE ++R + E+E+ R
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ------ERERQYR 1051
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
E+E + + E +L RE+ ++ L ++Y + ++ +E+LL E R+ +
Sbjct: 1052 ---EEEELQQE---EEQLLGEERETRRRQELERQYRKEEE-LQQEEEQLLREEPEKRRRQ 1104
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQD-EREVKEEEEQQEEEEVRSAE 1002
E+ E+ ++L++ +E +E++ Q+ ER+ +EEEE Q+EEE E
Sbjct: 1105 ERERQCREE--------EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 1003 NSSK 1006
K
Sbjct: 1157 EPEK 1160
Score = 53.5 bits (127), Expect = 1e-06
Identities = 48/188 (25%), Positives = 95/188 (50%), Gaps = 16/188 (8%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLI 882
+ E E+LL+E ++ E D F E+E + + QE ++ ++ E+E+L+
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR----QEREQQLRHDRDRKFREEEQLL 1676
Query: 883 RFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQA 942
+ GE++ + + E D +RE +Q L ++ E + E Q + E+E + R+
Sbjct: 1677 QE-GEEQQLRRQ---ERD--RKFREEEQQ--LRRQERERKFLQEEQQLRRQELERKFREE 1728
Query: 943 EE-KFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ---QEEEEV 998
E+ + E E+L K LEE + +E ++ + + +R+ +EEE+ +EE+++
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788
Query: 999 RSAENSSK 1006
RS E+ K
Sbjct: 1789 RSQESDRK 1796
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/179 (22%), Positives = 91/179 (50%), Gaps = 6/179 (3%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
++++R EEE + +++ E +E E++ + +++L+ E +ER E++ E+E+L +
Sbjct: 474 QQLKRDQEEERRERWLKLEEEE---RREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
+ ++ + + + L RE K+ ++ E +++LL+ E RQ
Sbjct: 531 RLRSEQQLRREQEERREQLLK-REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAE 1002
K E E+L L K +++E L R+E + ++E +E ++ + +E+EE R +
Sbjct: 590 LKREQE-ERLEQRL-KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Score = 52.4 bits (124), Expect = 2e-06
Identities = 47/188 (25%), Positives = 93/188 (49%), Gaps = 22/188 (11%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
+E E+LL EE + E++ ++++EE +E+ +L E E+ Q E+E+ R
Sbjct: 1058 QEEEQLLGEERETRRRQ-ELERQYRKEEELQQEEEQLLREEPEKRRRQ-----ERERQCR 1111
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
E+E + + E +L RE ++ L ++Y E V + +E+LL E R+ +
Sbjct: 1112 ---EEEELQQE---EEQLLREEREKRRRQELERQYREEEEV-QQEEEQLLREEPEKRRRQ 1164
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEE-QQEEEEVRSAE 1002
E L + ++L++ +E +E++ + ER+ +EEEE Q+++ + R +
Sbjct: 1165 E--------LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
Query: 1003 NSSKSPKK 1010
+S K
Sbjct: 1217 EDQRSDLK 1224
Score = 51.6 bits (122), Expect = 4e-06
Identities = 46/186 (24%), Positives = 90/186 (48%), Gaps = 24/186 (12%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEES-KEDRKLQEENKERAEEQPSTSTEKEKL 881
Y E E+L +EE ++ + E ++ +++ E ++D+KLQ++ ++ E+P +E+
Sbjct: 930 YREEEQLQQEE--EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Query: 882 IRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQ 941
++ E+E E +L RE ++ ++Y + ++ +E+LL E R+
Sbjct: 988 KKYREEEELQQE----EEQLLREEREKRRRQEWERQYRKKDE-LQQEEEQLLREEREKRR 1042
Query: 942 AEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREV-----KEEEEQQEEE 996
+E+ E+ EEL + EE+E + +E+ KEEE QQEEE
Sbjct: 1043 LQERERQYREE-----------EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE 1091
Query: 997 EVRSAE 1002
++ E
Sbjct: 1092 QLLREE 1097
Score = 49.7 bits (117), Expect = 1e-05
Identities = 49/202 (24%), Positives = 95/202 (47%), Gaps = 13/202 (6%)
Query: 816 RKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEE-----ESKEDRKLQEENKERAEE 870
R+ L EE E+L E ++ E E + +ED+E E + D+K + + +E +
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQEEE--DGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Query: 871 QPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQE 930
+ T K L + +++ + + E ++ RE ++ ++Y E ++ +E
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEE--EEELQREEREKRRRQEQERQYREEEQ-LQQEEE 941
Query: 931 KLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEE 990
+LL E R+ +E+ E Y K K + L R+ + EK+ ++E E+++EE
Sbjct: 942 QLLREEREKRRRQER-ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
Query: 991 EQ--QEEEEVRSAENSSKSPKK 1010
EQ +EE E R + + +K
Sbjct: 1001 EQLLREEREKRRRQEWERQYRK 1022
Score = 49.7 bits (117), Expect = 1e-05
Identities = 49/202 (24%), Positives = 93/202 (46%), Gaps = 23/202 (11%)
Query: 823 YEEIERLLEEEAVKEFIEP------EIDESFKEDEE-ESKEDRKLQEENKERAEEQPSTS 875
Y E E + +EE EP E++ ++E+EE + +E++ L+EE ++R +E+
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
Query: 876 TEKEKL------IRFIGEDENVHSKPLFETD---------VLSSWRESAKQGTLAQKYLE 920
E+E+L R+ ED+ K +E + V RE+ + L L
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR 1259
Query: 921 AMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKEN 980
+ +Q L E + R R+ E + ++ H + + EE R++ K ++E
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDR-HFPEEEQLEREEQKEAKRRDRKSQEEK 1318
Query: 981 QDEREVKEEEEQQEEEEVRSAE 1002
Q RE +EE+ +++E + + E
Sbjct: 1319 QLLREEREEKRRRQETDRKFRE 1340
Score = 48.9 bits (115), Expect = 2e-05
Identities = 49/213 (23%), Positives = 93/213 (43%), Gaps = 30/213 (14%)
Query: 816 RKITLLTYEEIER---LLEEEAVKEFIEPEIDESFKEDEEESKEDR--KLQEENK----E 866
R+ L E+ ER L EE + + + K D+EE + +R KL+EE + E
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 867 RAEEQPSTSTE--KEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAV 924
R E+Q E +E+ ++ E+E + + E + E +Q +
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ------------L 549
Query: 925 IEHMQEKLLEVENRARQAEEKFEDAYEKL-------HHTLIKNKDLEELVMTSRKESKEE 977
++ +EK LE E R ++ + + E+ ++L +K + E L ++E E
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 978 KENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
E ++ RE + + E+ EEE + S + ++
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Score = 48.9 bits (115), Expect = 2e-05
Identities = 40/193 (20%), Positives = 87/193 (45%), Gaps = 17/193 (8%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLI 882
+ E E+LL+E ++ E D F E+E++ + ++E + EQ S E E+
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLEEEQQLR-----RQERDRKFREQELRSQEPER-- 1515
Query: 883 RFIGEDENVHSKPLF------ETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVE 936
+F+ E++ +H + E + R ++ +K+ E + + +E+ L +
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575
Query: 937 NRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEE 996
R R KF +K+ + K +E+ R+E +++ + +R+ +E+E+ +E
Sbjct: 1576 ERDR----KFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Query: 997 EVRSAENSSKSPK 1009
E + + K
Sbjct: 1632 EEQQLHRQERDRK 1644
Score = 48.1 bits (113), Expect = 4e-05
Identities = 44/221 (19%), Positives = 89/221 (40%), Gaps = 31/221 (14%)
Query: 821 LTYEEIERLLEEEAVKEFIEPEIDES------FKEDEEESKEDRKLQEENKERAEEQPST 874
L EE+ERL +EE ++ ++ E E K +E+E + ++L+ E +ER E++
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 875 STEKEKL-------------IRFIGEDENVHSKPLFETDVLS-SWRESAKQGTLAQKYLE 920
E+E+L + + E+E ++ ++ + W+ ++ K
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 921 AMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEK-- 978
E + + + E R R+ E E+ H + + + + E K E+
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 979 ---------ENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
Q ER+++ EE QQ E+ E + ++
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
Score = 48.1 bits (113), Expect = 4e-05
Identities = 46/175 (26%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 827 ERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIG 886
E+LL EE K + E ++ ++E+EE +E+ +L E +E+ Q ++K
Sbjct: 971 EQLLGEEPEKRRRQ-EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK------ 1023
Query: 887 EDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKF 946
DE E +L RE + ++Y E ++ +E+LL E R+ +E
Sbjct: 1024 -DELQQE----EEQLLREEREKRRLQERERQYREEEE-LQQEEEQLLGEERETRRRQE-L 1076
Query: 947 EDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ--QEEEEVR 999
E Y K + + L R+ + E++ ++E E+++EEEQ +EE E R
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Score = 47.8 bits (112), Expect = 5e-05
Identities = 39/188 (20%), Positives = 86/188 (45%), Gaps = 9/188 (4%)
Query: 821 LTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEK 880
L E+ R +EE +E E ++ + +++E + +++L+ E +ER E+Q E+E+
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 881 LIRFI--GEDENVHSKPLFETDVLSSWRESAKQGTL-------AQKYLEAMAVIEHMQEK 931
+ + ++E + L L ++ ++ L ++ L + Q+
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 932 LLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEE 991
E + R Q EE+ E +E+ ++ EE ++E + E+ Q+ R+ + + +
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 992 QQEEEEVR 999
Q+EE R
Sbjct: 480 QEEERRER 487
Score = 47.4 bits (111), Expect = 7e-05
Identities = 40/186 (21%), Positives = 83/186 (44%), Gaps = 11/186 (5%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
E ER EEE ++ E +E E++ +E +L+ + +E ++Q +E+ R
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ-----RRERQDR 236
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
E+E K + + + E Q Q+ E E +++ + R RQ E
Sbjct: 237 VFQEEEE---KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDER---EVKEEEEQQEEEEVRS 1000
E+ + + K ++ R+E +E +E Q+ER +++ E+E++ E+++R
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 1001 AENSSK 1006
+ +
Sbjct: 354 EQEEER 359
Score = 47.4 bits (111), Expect = 7e-05
Identities = 50/212 (23%), Positives = 97/212 (45%), Gaps = 22/212 (10%)
Query: 816 RKITLLTYEEIERLLEEEAVKEFIEPEIDES----FKEDEEESKEDRKLQEENKERAEEQ 871
R+ L EE ER ++E ++ + E +E K EEE + ++L+ E + R E++
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 872 PSTST----EKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAV-IE 926
E+EK + ++ + + D L E +Q L ++ E + ++
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
Query: 927 HMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTS-RKESKEEKENQDERE 985
+ + LE E R R+ K E+ E+ L+K+++ EE R+E +E +E + +RE
Sbjct: 604 REEVERLEQEER-REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 986 VKEE-----------EEQQEEEEVRSAENSSK 1006
+EE EE++E+E + ++
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Score = 47.0 bits (110), Expect = 9e-05
Identities = 44/182 (24%), Positives = 83/182 (45%), Gaps = 5/182 (2%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLI 882
Y + E L +EE EPE +E E + +E+ +LQ+E ++ E+ +++L
Sbjct: 1080 YRKEEELQQEEEQLLREEPE-KRRRQERERQCREEEELQQEEEQLLREE-REKRRRQELE 1137
Query: 883 RFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQA 942
R E+E V + E +L E ++ L ++Y E + + ++ L E + + RQ
Sbjct: 1138 RQYREEEEVQQE---EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Query: 943 EEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAE 1002
E+ E+L K + +E + K E ++ R+ K + +E E+ R E
Sbjct: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLE 1254
Query: 1003 NS 1004
+S
Sbjct: 1255 DS 1256
Score = 46.6 bits (109), Expect = 1e-04
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 825 EIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRK----LQEENKERAEEQPSTSTEKEK 880
E E +EE ++ E+ +E++++ + +R+ +EE KE + + E+EK
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 881 LIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLL-EVENRA 939
L E+E + L E + R+ +Q ++ E E Q++L E + R
Sbjct: 260 L----QEEEPQRQRELQEEE--EQLRKLERQELRRERQEE-----EQQQQRLRREQQLRR 308
Query: 940 RQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQ----EE 995
+Q EE+ E E+ + + E R+E +E +E Q RE +EE +Q E+
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 996 EEVR 999
EE R
Sbjct: 369 EEER 372
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/176 (24%), Positives = 77/176 (43%), Gaps = 21/176 (11%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
EE ++ E + F E E E K + KE+ KLQEE +R E E+E+ +R
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ----EEEEQLR 279
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
+ E RE ++ Q+ + +E+ E + R+ +
Sbjct: 280 KLERQE--------------LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVR 999
E+ E E+ L + ++ E R+E +EE+ Q R +E+EE++ E+++R
Sbjct: 326 ERREQQEERREQQLRREQE-ERREQQLRREQEEERREQQLR--REQEEERREQQLR 378
Score = 46.6 bits (109), Expect = 1e-04
Identities = 48/210 (22%), Positives = 95/210 (45%), Gaps = 20/210 (9%)
Query: 816 RKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAE-----E 870
R+ L +++ R EEE ++ E E E + E+E + D +EE ER E +
Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQ 474
Query: 871 QPSTSTEKEKLIRFIG-EDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQ 929
Q E+E+ R++ E+E + L +E ++ L ++ E E +Q
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE-----ERLQ 529
Query: 930 EKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKES-----KEEKENQDER 984
++L + R+ EE+ E ++ ++ + E+ + ++E K E+E + +R
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Query: 985 EVKEEEEQQEE----EEVRSAENSSKSPKK 1010
+E+EE+ E+ EEV E + ++
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQR 619
Score = 46.6 bits (109), Expect = 1e-04
Identities = 50/200 (25%), Positives = 95/200 (47%), Gaps = 27/200 (13%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEE-ESKEDRKLQEENKERAEEQPSTSTEKEKLI 882
+E E+LL EE K + E++ ++E+EE + +E++ L+EE ++R +E+ E+E+L
Sbjct: 1148 QEEEQLLREEPEKRRRQ-ELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Query: 883 R------FIGEDENVHSKPLFETD---------VLSSWRESAKQGTLAQKYLEAMAVIEH 927
R + ED+ K +E + V RE+ + L L +
Sbjct: 1207 RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQD 1266
Query: 928 MQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESK-EEKENQDEREV 986
+Q L E + R R+ E + ++ + E+L +KE+K ++++Q+E+++
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHF------PEEEQLEREEQKEAKRRDRKSQEEKQL 1320
Query: 987 KEEEEQQEEEEVRSAENSSK 1006
EE EE+ R E K
Sbjct: 1321 LREE---REEKRRRQETDRK 1337
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/194 (21%), Positives = 89/194 (45%), Gaps = 22/194 (11%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
++++ LL E+ ++ + +++ + E+ +L+ E ++ A+ + S E+++L+R
Sbjct: 1265 QDLQHLLGEQQERD--REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
+E + ETD R+ ++ L Q+ E + K E E R ++
Sbjct: 1323 ----EEREEKRRRQETD-----RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ----------- 992
KF + ++L + K L+E +E +++ +R+ +EEE+Q
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433
Query: 993 QEEEEVRSAENSSK 1006
+EE++VR E K
Sbjct: 1434 EEEQQVRRQERERK 1447
Score = 45.8 bits (107), Expect = 2e-04
Identities = 46/195 (23%), Positives = 87/195 (44%), Gaps = 28/195 (14%)
Query: 825 EIERLLEEEAVKEFIEPEIDESFKEDEE--ESKEDRKLQEEN--KERAEEQPSTSTEKEK 880
E E+L +E ++ +E E +E+++ + DRK +EE ++ EEQ S E ++
Sbjct: 1736 EQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Query: 881 LIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRAR 940
R E+E + R+ ++ L + + E Q +L E E R R
Sbjct: 1796 KFR---EEEQL--------------RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 941 QAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEE---EEQQEEEE 997
Q ++ A E+ ++ +EL +E ++++ + ER+++EE +Q+EE+
Sbjct: 1839 QERDRQYRAEEQFATQEKSRREEQEL----WQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Query: 998 VRSAENSSKSPKKGH 1012
R KGH
Sbjct: 1895 HRQVGEIKSQEGKGH 1909
Score = 44.7 bits (104), Expect = 5e-04
Identities = 58/291 (19%), Positives = 120/291 (41%), Gaps = 22/291 (7%)
Query: 738 DIGVARLELDA---IELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDK 794
D+ + L+LD+ ++ L +C + A L + + + E L + D+
Sbjct: 55 DLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQ-DR 113
Query: 795 LKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEP-EIDESFKEDEEE 853
++E L G++ E+ L E E E E E + + DEE
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
Query: 854 SKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGT 913
++ ++ QE + RAEE+ S + + F ++E + + L E + RE +Q
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEF-PDEEQLRRRELLE--LRRKGREEKQQQR 230
Query: 914 LAQK-----------YLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKD 962
++ + + V+ +EKL E E + ++ ++ E+ KL ++ +
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 963 LEELVMTSRKESKEE---KENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
EE R +++ K+ ++ RE +EE +Q+E + E + ++
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Score = 44.7 bits (104), Expect = 5e-04
Identities = 45/223 (20%), Positives = 91/223 (40%), Gaps = 32/223 (14%)
Query: 816 RKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDR----------------- 858
R+ L EE E LE+ +E E ++ E+E+E +R
Sbjct: 654 RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEAD 713
Query: 859 ---------KLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFET---DVLSSWR 906
++E + R +EQ +E +++ E+E H + E D W+
Sbjct: 714 ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQW-QEEERAHRQQQEEEQRRDFTWQWQ 772
Query: 907 ESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEEL 966
K Q+ L A + +E+ L E R +Q E++F E+ + ++ E+
Sbjct: 773 AEEKSERGRQR-LSARPPLREQRERQLRAEER-QQREQRFLPEEEEKEQRRRQRREREKE 830
Query: 967 VMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPK 1009
+ +E + ++ + ++ +EE+ QE++E R ++ + K
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Score = 44.7 bits (104), Expect = 5e-04
Identities = 42/189 (22%), Positives = 89/189 (47%), Gaps = 21/189 (11%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDR--KLQEENKERAEEQPSTSTEKEKL 881
EE ++L ++ ++F++ E +E ++ ++DR K +EE + R E + + +E+
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
Query: 882 IRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQ 941
+F E++ V + E + ++ +Q E Q+ E + + R+
Sbjct: 1579 RKFRLEEQKVRRQEQ-ERKFMEDEQQLRRQ--------------EGQQQLRQERDRKFRE 1623
Query: 942 AEEKFEDAYEK-LHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ---QEEEE 997
E+ ++ E+ LH K LEE R+E +++ + +R+ +EEE+ EE++
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Query: 998 VRSAENSSK 1006
+R E K
Sbjct: 1684 LRRQERDRK 1692
Score = 44.3 bits (103), Expect = 6e-04
Identities = 42/179 (23%), Positives = 81/179 (45%), Gaps = 19/179 (10%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLI 882
+ E E+LL+E ++ E D F+E+E++ L+ + +ER Q +++L
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQ------LRRQERERKFLQEEQQLRRQELE 1722
Query: 883 RFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQA 942
R E+E + ET+ +E ++ +K LE + +E+ L + R R+
Sbjct: 1723 RKFREEEQLRQ----ETE-----QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF 1773
Query: 943 EE----KFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEE 997
E + E ++L K EE + +E ++ + Q + + + EEEQ + EE
Sbjct: 1774 REEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/207 (20%), Positives = 86/207 (41%), Gaps = 27/207 (13%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAE---------EQPST 874
+E E+LL EE K + E++ ++E+EE +E+ +L E E+ E+
Sbjct: 1118 QEEEQLLREEREKRRRQ-ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEEL 1176
Query: 875 STEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLE 934
E+E+L+R E + + + E ++ Q+Y + + + E
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREE------EELQRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 935 VENRAR--------QAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKE---NQDE 983
EN R + E+F + +DL+ L+ ++ +E++ Q +
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
Query: 984 REVKEEEEQQEEEEVRSAENSSKSPKK 1010
R EEE+ + EE+ + KS ++
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEE 1317
Score = 41.2 bits (95), Expect = 0.005
Identities = 39/182 (21%), Positives = 82/182 (45%), Gaps = 22/182 (12%)
Query: 831 EEEAVKEFIEPEIDESFKEDEE--ESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGED 888
EEE ++ + E K++EE E +E+R+ Q+E +E+ EE+ +E+ +R E+
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER------REQQLRREQEE 345
Query: 889 ENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFED 948
E + E ++ L ++ E + +E+ L E + R+ ++ +
Sbjct: 346 RR-------EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 949 AYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSP 1008
+ L + + L R+E + +E Q RE +EE +Q+ E+ R + +
Sbjct: 399 QQLRREQQLRREQQL-------RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 1009 KK 1010
++
Sbjct: 452 EE 453
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 61.2 bits (147), Expect = 5e-09
Identities = 45/200 (22%), Positives = 93/200 (46%), Gaps = 13/200 (6%)
Query: 814 KGRKITLLTYEEIERLLEEEAVKEFIEPEI---DESFKEDEEESKEDRKLQEENKERAEE 870
K RK + + ERL E+E E ++ ++ +E E+E +E K E KE E+
Sbjct: 287 KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
Query: 871 QPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQE 930
+ ++EK+ ++E + + WR+ + ++ E + +E
Sbjct: 347 EEQMQEQEEKMWE---QEEKMREQEE------KMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 931 KLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEE 990
++ E + R R+ EE+ + EK+ + K ++ +++ +K +E++ Q+E ++E E
Sbjct: 398 RMWEQDERLREKEERMREQ-EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 991 EQQEEEEVRSAENSSKSPKK 1010
++ EEE E K K+
Sbjct: 457 KKMREEEETMREQEEKMQKQ 476
Score = 57.4 bits (137), Expect = 7e-08
Identities = 46/186 (24%), Positives = 88/186 (47%), Gaps = 11/186 (5%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
E +E+ +E+ K + + +E +E+E + ++K++EE + E++ ++EK+
Sbjct: 565 ERMEKKTQEQEKKTWDQ---EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
E++ + + W + K +K E + E +EKL E E Q +
Sbjct: 622 --QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE-QKEKLWEHEK--MQEQ 676
Query: 944 EKFEDAYEKL-HHTLIKNKDLEELVMTSRKESKEEKENQDERE--VKEEEEQQEEEEVRS 1000
EK ++ EK+ ++ K E+ T +E E+E+ ERE ++EEEE E+E +
Sbjct: 677 EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKM 736
Query: 1001 AENSSK 1006
E K
Sbjct: 737 QEQEEK 742
Score = 56.6 bits (135), Expect = 1e-07
Identities = 41/175 (23%), Positives = 84/175 (48%), Gaps = 11/175 (6%)
Query: 842 EIDESFKEDEEESKEDRKLQE------ENKERAEEQPSTSTEKEKLIRFIGEDENVHSKP 895
E DE +E EE +E K+ E E K+ E++ T ++EK+ E+E + +
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM----QEEERIRERE 456
Query: 896 LFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHH 955
+ + RE ++ ++ + E Q++L E + + + +EK ++ EK+
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQEQEEKIWE 515
Query: 956 TLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
K +D EE+ +K ++EK + E ++ E+EE+ ++E + + + KK
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKK 570
Score = 55.8 bits (133), Expect = 2e-07
Identities = 46/230 (20%), Positives = 98/230 (42%), Gaps = 6/230 (2%)
Query: 785 ATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEI- 843
A + E+ KE + LL ++ + + + E L E+E E ++
Sbjct: 237 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296
Query: 844 --DESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDV 901
+E +E E + +E + ++R EQ E+EK +R + E + +
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR--EQKELREQEEQMQEQE 354
Query: 902 LSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNK 961
W + K +K + ++++ E E + R EE+ + E+L + +
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
Query: 962 DLEELVMTSRKESKEEKENQDEREVKEEEEQ-QEEEEVRSAENSSKSPKK 1010
+ E++ K +E+K + E++ +++EE+ QEEE +R E + ++
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Score = 55.5 bits (132), Expect = 3e-07
Identities = 46/190 (24%), Positives = 89/190 (46%), Gaps = 16/190 (8%)
Query: 822 TYEEIERLLEEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKE 879
T+++ E++ EEE ++E + E +E +E EE+ +E + +E +E+ EQ E+E
Sbjct: 578 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE 637
Query: 880 KLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA 939
+ + E + ++E L +E + Q+ QEK+ E E +
Sbjct: 638 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-----------QEKMQEQEEKI 686
Query: 940 RQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKE---NQDEREVKEEEEQQEEE 996
+ E+ + E+ T + K EE M R++ E+E + E +++E+EE+ +E+
Sbjct: 687 WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 997 EVRSAENSSK 1006
E E K
Sbjct: 747 EEEMWEQEEK 756
Score = 55.1 bits (131), Expect = 3e-07
Identities = 47/201 (23%), Positives = 91/201 (45%), Gaps = 15/201 (7%)
Query: 824 EEIERLLEEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTE---K 878
E+ E+L E+E ++E E E +E ++ EE +++K+ + K R +E E +
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 879 EKLIRFIGEDENVHSKPLFET----DVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLE 934
++ + ++E + K + D RE + +K E ++ +EK+ E
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 935 VENRARQAEEKFEDAYEKLHHTLIKNKDLEELV------MTSRKESKEEKENQDEREVKE 988
E + ++ EEK + EK+ K + EE + M ++ E+KE E E +
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 674
Query: 989 EEEQQEEEEVRSAENSSKSPK 1009
E+E+ +E+E + E K
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKK 695
Score = 52.8 bits (125), Expect = 2e-06
Identities = 40/199 (20%), Positives = 100/199 (50%), Gaps = 19/199 (9%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLI 882
+E++E++ EE+ ++E ++ ++ EE+ +E+ +++E K+ EE+ + ++EK+
Sbjct: 420 WEQVEKMREEKKMQEQ-----EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQ 474
Query: 883 RFIGEDENV--HSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHM---------QEK 931
+ ++EN+ + ++ L +E + Q+ E + E QEK
Sbjct: 475 K---QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 531
Query: 932 LLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEE 991
+ + + R+ E++ + EK+ K D EE + +E +++ +Q+E+ +EE
Sbjct: 532 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM 591
Query: 992 QQEEEEVRSAENSSKSPKK 1010
++ E+++R E + ++
Sbjct: 592 REREKKMREEEEMMREQEE 610
Score = 52.4 bits (124), Expect = 2e-06
Identities = 42/189 (22%), Positives = 93/189 (49%), Gaps = 9/189 (4%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEES-KEDRKLQEENKERAEEQPSTSTEKEKL 881
+E+ E++ ++E E +++ +E E+++ ++ K++EE ER E+ E+E++
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE--ERMREREKKMREEEEM 604
Query: 882 IRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQ 941
+R E + + E + W + K +K E + +EK+ E + Q
Sbjct: 605 MREQEEKMQEQEEKMQEQEE-KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Query: 942 AEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSA 1001
E+ +E +EK+ K ++ EE + +E E+K + E++ ++E+ +EEE +R
Sbjct: 664 KEKLWE--HEKMQEQE-KMQEQEEKIW--EQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 1002 ENSSKSPKK 1010
E + ++
Sbjct: 719 EKKMREEEE 727
Score = 52.0 bits (123), Expect = 3e-06
Identities = 41/179 (22%), Positives = 85/179 (47%), Gaps = 5/179 (2%)
Query: 824 EEIERLLEEEAVKEFIEPEI--DESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKL 881
E++E+ +E+ K + + ++ +ES +E E++ +E+ ++ E +E+ +EQ E+E+
Sbjct: 690 EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Query: 882 IRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQ---KYLEAMAVIEHMQEKLLEVENR 938
+ E + ++E L +E + Q K E + +EK+ E +
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEK 809
Query: 939 ARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEE 997
R EEK EK+ K EE + ++ ++E +E+ +EE+ +E+EE
Sbjct: 810 MRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE 868
Score = 51.6 bits (122), Expect = 4e-06
Identities = 56/225 (24%), Positives = 93/225 (41%), Gaps = 30/225 (13%)
Query: 787 EDLYEVDKLKKECYE-----WINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEP 841
E ++E +K++K+ E W +++ R+ + EE+ R EE+
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKM------Q 737
Query: 842 EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDV 901
E +E +E EEE E + E +E+ EQ +KEKL E E + +
Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL----WEHEKMQEQE------ 787
Query: 902 LSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNK 961
W + K +K + +EK+ E + R EEK EK+ K
Sbjct: 788 -KIWEQEEKMRDQEEK-------MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMW 839
Query: 962 DLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSK 1006
EE M ++E EEK E +++E+EE+ +E + E K
Sbjct: 840 GQEE-KMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Score = 50.4 bits (119), Expect = 8e-06
Identities = 44/187 (23%), Positives = 86/187 (45%), Gaps = 19/187 (10%)
Query: 824 EEIERLLEEEAVKEFIEPEI---DESFKEDEEESKEDRKLQEENK-----ERAEEQPSTS 875
E+ E++ E+E + E ++ +E E EE+ E ++L E+ + E+ +EQ
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 876 TEKEKLIRFIGEDENVHSKPLFETDVLSSW-----RESAKQGTLAQKYLEAMAVIEHMQE 930
++EK I E E + K + +W RE +K E ++ +E
Sbjct: 681 EQEEK----IWEQEKMEKKT--QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEE 734
Query: 931 KLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEE 990
K+ E E + ++ EE+ + EK+ K + + L K + EK + E+ ++EE
Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Query: 991 EQQEEEE 997
+ +++EE
Sbjct: 795 KMRDQEE 801
Score = 48.9 bits (115), Expect = 2e-05
Identities = 45/201 (22%), Positives = 93/201 (46%), Gaps = 13/201 (6%)
Query: 822 TYEEIERLLEEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKE 879
T ++ E++ EEE ++E + E +E+ +E EE+ ++ + E +E+ +Q +KE
Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 498
Query: 880 KLI---RFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVE 936
KL + ++E + + D W + K +K E + +EK+ + E
Sbjct: 499 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR-QEKMREQEDQMWEQEEKMRDQE 557
Query: 937 NRARQAEEKFEDAYEKLHHTLIKNKDL---EELVMTSRKESKEEKENQDEREVK----EE 989
+ EE+ E ++ ++ EE + K+ +EE+E E+E K EE
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 990 EEQQEEEEVRSAENSSKSPKK 1010
+ Q++EE++ E + ++
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEE 638
Score = 35.8 bits (81), Expect = 0.21
Identities = 37/161 (22%), Positives = 69/161 (42%), Gaps = 17/161 (10%)
Query: 824 EEIERLLEEEAVKEFIEPEI---DESFKEDEEESKEDRKLQEENK-----ERAEEQPSTS 875
E+ E++ E+E + E E+ +E E EE+ E ++L E+ + E+ +EQ
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 876 TEKEKLI----RFIGEDENVHSKP-LFETDVLSSWRESAKQGTLAQKYL----EAMAVIE 926
++EK+ + G++E + + W + K +K + E
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 927 HMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELV 967
M+EK+ E + R+ EEK EK+ K + EE +
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 33.5 bits (75), Expect = 1.0
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 16/134 (11%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEES---KEDRKLQEENKERAEEQPSTSTEKEK 880
E+ E+L E E ++E + E D+EE +E++ +E K R +E+ E+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEE-- 829
Query: 881 LIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRAR 940
+ G++E + + W + K Q E M +EK+ E + R
Sbjct: 830 --KMWGQEEKMWGQEE------KMWGQEEKMEEKMQGQEEKM---REQEEKMRGQEEKMR 878
Query: 941 QAEEKFEDAYEKLH 954
+ EEK EK++
Sbjct: 879 EQEEKMRGQEEKIY 892
Score = 30.8 bits (68), Expect = 6.7
Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 16/136 (11%)
Query: 873 STSTEKEKLIRFIGEDENVHSKPLFETDVLSS--WRESAKQGTLAQKYLEAMAVIEHMQE 930
+ ST +K R+I E E D LS +R + L +K E +QE
Sbjct: 187 AVSTRHKKADRYIEELTK-------ERDALSLELYRNTITNEELKKKNAE-------LQE 232
Query: 931 KLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEE 990
KL E+ + + ++ KL ++ + +EE+ + E++++++E
Sbjct: 233 KLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 292
Query: 991 EQQEEEEVRSAENSSK 1006
E+ +E R E K
Sbjct: 293 EKMWRQEERLREQEGK 308
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 61.2 bits (147), Expect = 5e-09
Identities = 52/226 (23%), Positives = 104/226 (46%), Gaps = 6/226 (2%)
Query: 785 ATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEID 844
A + E+ KE + LL ++ + + + E L E+E + I + +
Sbjct: 199 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE---KKIRKQEE 255
Query: 845 ESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSS 904
+ ++++E +++ K++E+ +E+ Q E+EK +R E E K L E +
Sbjct: 256 KMWRQEERLREQEGKMREQ-EEKMRRQEKRLREQEKELRE-QEKELREQKKLREQEEQMQ 313
Query: 905 WRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLE 964
+E K +K E + +E+L E E + R+ E+K D E++ + ++ E
Sbjct: 314 EQEE-KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 372
Query: 965 ELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
E + K ++E++ Q+E ++E E++ EEE E K K+
Sbjct: 373 ERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Score = 58.2 bits (139), Expect = 4e-08
Identities = 44/208 (21%), Positives = 97/208 (46%), Gaps = 21/208 (10%)
Query: 823 YEEIERLLEEEAVKEFIEPEID--------ESFKEDEEESKEDRKLQEENKERAEEQPST 874
+++ E++ EE+ +E + D E +E E++ +E+ ++ E +E+ +EQ
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 875 STEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYL--EAMAVIEHMQEKL 932
E+E+ + E + ++E + W + + Q+ + E ++ +EK+
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEE-KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648
Query: 933 LEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKE----------NQD 982
E E + R+ EEK + EK+ K ++ EE + ++ +E++E Q+
Sbjct: 649 WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708
Query: 983 EREVKEEEEQQEEEEVRSAENSSKSPKK 1010
E+ +EE+ +EE+R E + K+
Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKE 736
Score = 55.1 bits (131), Expect = 3e-07
Identities = 42/194 (21%), Positives = 94/194 (48%), Gaps = 7/194 (3%)
Query: 823 YEEIERLLEEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEK 880
+E+ E++ EEE ++E + E +E+ +E EE+ ++ + E +E+ +Q +KEK
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Query: 881 LI---RFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVEN 937
L + ++E + + D W + K +K E + +EK+ + E
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR-QEKMREQEDQMWEQEEKMRDQEQ 500
Query: 938 RARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ-QEEE 996
+ EE+ + E+L + ++ +++ K +E+K + E++ ++EE+ +EEE
Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 997 EVRSAENSSKSPKK 1010
+R E + ++
Sbjct: 561 RMREREKKMREEEE 574
Score = 54.3 bits (129), Expect = 6e-07
Identities = 45/201 (22%), Positives = 88/201 (43%), Gaps = 14/201 (6%)
Query: 822 TYEEIERLLEEEAVKEFIEP---------EIDESFKEDEEESKEDRKLQEENKERAEEQP 872
T+++ E++ EEE ++E + E +E +E EE+ +E + E +E+ +EQ
Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
Query: 873 STSTEKE-KLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEK 931
E+E K+ ED+ + + + K +K E + +EK
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Query: 932 LLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEE 991
+ E + R+ EEK + EK+ K + EE + +E+ Q+E+ +EE
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMW----GQEEKMWGQEEKMWGQEEM 724
Query: 992 QQEEEEVRSAENSSKSPKKGH 1012
+++EE +R + + H
Sbjct: 725 REKEERIRDQKEKMQERLPEH 745
Score = 52.8 bits (125), Expect = 2e-06
Identities = 50/208 (24%), Positives = 93/208 (44%), Gaps = 29/208 (13%)
Query: 824 EEIERLLEEEAVKEFIEP--EIDESFKEDEE--------------ESKEDRKLQEENKER 867
E+ E+L E+E ++E E E +E ++ EE +ED+ ++E K R
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Query: 868 AEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAK---QGTLAQKYLEAMAV 924
+EQ E+ R +DE + K + W++ K + ++ +
Sbjct: 497 DQEQKMWDQEE----RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Query: 925 IEHM--QEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQD 982
E M +E++ E E + R+ EE + EK+ K ++ EE + ++ +E++E
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Query: 983 EREVK----EEEEQQEEEEVRSAENSSK 1006
E+E K EEE++ +E+E E K
Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/176 (24%), Positives = 80/176 (45%), Gaps = 9/176 (5%)
Query: 831 EEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGED 888
EEE ++E E E +E +E EE+ E + +E +E+ EQ E+E+ + ++
Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 889 ENV-HSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFE 947
E + + + W + K +K E ++ +EK+ E E + + EEK
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMR 691
Query: 948 DAYEKLHHTLIKNKDLEELV------MTSRKESKEEKENQDEREVKEEEEQQEEEE 997
+ EK+ K EE + M ++E +E++E +++ K +E E EE
Sbjct: 692 EQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 51.2 bits (121), Expect = 5e-06
Identities = 48/190 (25%), Positives = 84/190 (44%), Gaps = 17/190 (8%)
Query: 814 KGRKITLLTYEEIERLLEEEAVKEFIEPEI---DESFKEDEEESKEDRKLQEENKERAEE 870
K RK + + ERL E+E E ++ ++ +E E+E +E K E K+ E+
Sbjct: 249 KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQ 308
Query: 871 QPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQE 930
+ ++EK+ + K + + L W + + QK + + E
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERL--WEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 931 KLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKE---NQDEREVK 987
+L E E R R+ E+ +E EK+ EE + K+ +EE+E Q+E+ K
Sbjct: 367 RLREKEERMREQEKMWEQE-EKMQE--------EERIREREKKMREEEETMREQEEKMQK 417
Query: 988 EEEEQQEEEE 997
+EE E+EE
Sbjct: 418 QEENMWEQEE 427
Score = 50.8 bits (120), Expect = 6e-06
Identities = 38/165 (23%), Positives = 79/165 (47%), Gaps = 23/165 (13%)
Query: 842 EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDV 901
E ++ +E E+E +E +KL+E+ +E+ +EQ E+E+ +R E E
Sbjct: 287 EQEKELREQEKELREQKKLREQ-EEQMQEQEEKMWEQEEKMR---EQEE----------- 331
Query: 902 LSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNK 961
WR+ + ++ E + +E++ E + R R+ EE+ + EK+ K +
Sbjct: 332 -KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ-EKMWEQEEKMQ 389
Query: 962 DLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSK 1006
+ E + +E+K ++E ++E+EE+ +++E E K
Sbjct: 390 EEERI------REREKKMREEEETMREQEEKMQKQEENMWEQEEK 428
Score = 50.8 bits (120), Expect = 6e-06
Identities = 47/189 (24%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 824 EEIERLLEEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKL 881
E+ + L E++ ++E E E +E E EE+ +E + +ER EQ E+E+
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 353
Query: 882 IRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQ 941
+R ++E + + + RE K +K E + E ++K+ E E R+
Sbjct: 354 MR--DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER-EKKMREEEETMRE 410
Query: 942 AEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSA 1001
EEK + E + K + L E KE+ Q++ + +EE+ ++EE++R
Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQQRL-----PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 1002 ENSSKSPKK 1010
E KK
Sbjct: 466 EEMWGQEKK 474
Score = 50.1 bits (118), Expect = 1e-05
Identities = 48/204 (23%), Positives = 93/204 (45%), Gaps = 40/204 (19%)
Query: 823 YEEIERLLE-EEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKL 881
+E+ ERL E EE ++E E E EE+ +E+ +++E K+ EE+ + ++EK+
Sbjct: 362 WEQDERLREKEERMRE------QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 882 IRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQ 941
+ ++EN+ W + K+ Q+ L QEK+ E E + +
Sbjct: 416 QK---QEENM-------------WEQEEKEWQ--QQRLPEQKEKLWEQEKMQEQEEKIWE 457
Query: 942 AEEKFED-----AYEKLHHTLIKNKDLEELVMTSRKESKEEKEN----------QDEREV 986
EEK D EK K ++ E+ + ++ +++++ QDER
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 987 KEEEEQQEEEEVRSAENSSKSPKK 1010
++EE +E++++ E + KK
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKK 541
Score = 30.4 bits (67), Expect = 8.8
Identities = 16/79 (20%), Positives = 36/79 (45%)
Query: 928 MQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVK 987
+QEKL E+ + + ++ KL ++ + +EE+ + E++++
Sbjct: 192 LQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 251
Query: 988 EEEEQQEEEEVRSAENSSK 1006
++EE+ +E R E K
Sbjct: 252 KQEEKMWRQEERLREQEGK 270
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 60.8 bits (146), Expect = 6e-09
Identities = 51/208 (24%), Positives = 96/208 (46%), Gaps = 15/208 (7%)
Query: 814 KGRKITLLTYEEIERLLE-EEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENK----E 866
K RK + + E++ E EE ++E E +E +E EE +E+ K+ E+ K E
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Query: 867 RAEEQPSTSTEKEKLIR------FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLE 920
+ +EQ +E+ IR + E++ + + W++ K +K E
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE 623
Query: 921 AMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKE--SKEEK 978
I +EK+ E E ++ EEK + EK+ K ++ EE + ++ +E+K
Sbjct: 624 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK 683
Query: 979 ENQDEREVKEEEEQQEEEEVRSAENSSK 1006
+ E +++E+EE +E+E + E K
Sbjct: 684 IREQEEKIREQEEMMQEQEEKMWEQEEK 711
Score = 59.7 bits (143), Expect = 1e-08
Identities = 48/195 (24%), Positives = 91/195 (46%), Gaps = 10/195 (5%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKL--QEENKERAEEQPSTSTEKEK 880
+ + E++ E+E E I + ++ ++++E+ +++ K+ QEE R EE+ E +
Sbjct: 492 WRQKEKMHEQE---EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR 548
Query: 881 LIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRAR 940
+ E E + + + WR+ K +K I +EK E E +
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 941 QAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVK---EEEEQQEEEE 997
+ EEK + EK+ K ++ EE + + ++E++E E+E K +EE+ QE+EE
Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Query: 998 V--RSAENSSKSPKK 1010
R E + KK
Sbjct: 669 TMWRQEEKIREQEKK 683
Score = 58.2 bits (139), Expect = 4e-08
Identities = 43/180 (23%), Positives = 87/180 (48%), Gaps = 12/180 (6%)
Query: 831 EEEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGED 888
+EE ++E E +E +E EE+ +E + + +E+ EQ E+E+ IR ++
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR--EQE 632
Query: 889 ENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFED 948
E + E + ++ +E K G +K E ++ +E + E + R+ E+K +
Sbjct: 633 EKIR-----EQEEMTQEQEE-KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686
Query: 949 AYEKLHHTLIKNKDLEELVMTSRKE--SKEEKENQDEREVKEEEEQQEEEEVRSAENSSK 1006
EK+ ++ EE + ++ +EEK + E +++ +EE+ E+EVR + K
Sbjct: 687 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 57.0 bits (136), Expect = 9e-08
Identities = 50/208 (24%), Positives = 95/208 (45%), Gaps = 11/208 (5%)
Query: 814 KGRKITLLTYEEIERLLEEEAV---KEFIEPEIDESFKEDEEESKEDRKLQEENK----E 866
K R+ + +E+ E++ +E + KE E++E E E+ +++ K QEE K E
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 867 RAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIE 926
+ +EQ + +E+ IR E K ++ + +E ++ Q+ E E
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483
Query: 927 --HMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKE--SKEEKENQD 982
H QE++ + + + EEK EK+ K ++ EE + ++ +EEK +
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 543
Query: 983 EREVKEEEEQQEEEEVRSAENSSKSPKK 1010
E +EEE+ E+E++ E + K
Sbjct: 544 EEMWREEEKMHEQEKIWEEEKRQEQEDK 571
Score = 53.9 bits (128), Expect = 7e-07
Identities = 41/195 (21%), Positives = 91/195 (46%), Gaps = 32/195 (16%)
Query: 825 EIERLLEEEAVKEFIEPEIDESFKEDEEESKE-DRKLQEENKERAEEQPSTSTEKEKLIR 883
+++ +EE + + + +E EE+ +E + K+QE+ ++ E++ ++EK+ R
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
++E + W + K + E + +E + E E + R+ E
Sbjct: 340 ---QEEMM-------------WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 383
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQE--------E 995
E + EK+ ++LEE + K ++E++ Q+E +++E+E++QE E
Sbjct: 384 EMMWEKEEKI-------RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 996 EEVRSAENSSKSPKK 1010
E++R E + +K
Sbjct: 437 EKIREQEEKIREQEK 451
Score = 53.5 bits (127), Expect = 1e-06
Identities = 52/203 (25%), Positives = 87/203 (42%), Gaps = 16/203 (7%)
Query: 823 YEEIERLLE-EEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKE 879
+ + E++ E EE ++E E E +E +E EE+ + ++ E +E+ Q EKE
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362
Query: 880 KLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQ-----EKLLE 934
+ +R E+ + W + K L +K E + E + EK+ E
Sbjct: 363 EKMRR-QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 421
Query: 935 VENRARQA------EEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKE 988
E R Q EEK + EK+ K EE + K +EEK + E ++
Sbjct: 422 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 481
Query: 989 EEEQQEEEEV-RSAENSSKSPKK 1010
EE+ E+EE+ R E + +K
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEK 504
Score = 53.1 bits (126), Expect = 1e-06
Identities = 38/181 (20%), Positives = 89/181 (49%), Gaps = 24/181 (13%)
Query: 823 YEEIERLLEEEAVKEFIEPEI---DESFKEDEEESKE-DRKLQEENKERAEEQPSTSTEK 878
+ + E++ E+E ++ E ++ +E +E EE+ +E + K++E+ ++ E++ T ++
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Query: 879 EKLIRFIGEDEN--VHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVE 936
EK+ GE E + + + WR+ K I ++K+ E E
Sbjct: 647 EKM----GEQEEKMCEQEEKMQEQEETMWRQEEK--------------IREQEKKIREQE 688
Query: 937 NRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEE 996
+ R+ EE ++ EK+ K + EE + ++ + ++E E+EV+ +++++ +
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Query: 997 E 997
E
Sbjct: 749 E 749
Score = 37.4 bits (85), Expect = 0.072
Identities = 64/289 (22%), Positives = 119/289 (41%), Gaps = 40/289 (13%)
Query: 721 TDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTN 780
T C +E+ A R EL+A T ++ C+ MAL S +
Sbjct: 100 TSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILT--------CQKTELQMALYYSQH 151
Query: 781 SHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIE 840
+ K + ++ + +++ LS + +K Y IE L +E ++ +
Sbjct: 152 AVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRY--IEELTKE---RDALS 206
Query: 841 PEIDESFKEDEEESKEDRKLQEE----NKERAEEQPSTSTEKEKLIRFIGEDENVHSKPL 896
E+ + DEE +++ KLQE+ E++E Q + K KL R
Sbjct: 207 LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER------------- 253
Query: 897 FETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA-RQAEEKFEDAYEKLHH 955
+L ++ + K L++++ Q + E+ NR +Q EEK EK+
Sbjct: 254 --AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 956 TLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ--QEEEEVRSAE 1002
K ++ EE + +EEK + E +++ +EE ++EE++R E
Sbjct: 312 WEEKIQEQEEKI-----REQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 58.5 bits (140), Expect = 3e-08
Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 66/268 (24%)
Query: 804 NTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEE 863
N CL + I +K + + + +ERLLEE K+ E E ++ +E+ +E+R+L E
Sbjct: 665 NNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLEL 724
Query: 864 NKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSW------------------ 905
K +A+E T E E+ I G++ VH +P D SW
Sbjct: 725 MKVKAKEAEETDNEDEEEIE--GDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAV 782
Query: 906 -------------RESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRA------------- 939
+ +K+G +K E + + E ++ +V
Sbjct: 783 SEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILW 842
Query: 940 RQAEEKFEDAYEKLHHTLIKNKDLEELV-----------------MTSRKESKEEKENQD 982
+Q E +AY K+ + I ++ +EL+ +T +E ++ Q
Sbjct: 843 KQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQT 902
Query: 983 EREVKEEEEQQEEEEVRSAENSSKSPKK 1010
E EV EE E++EEEE E+ K K+
Sbjct: 903 EAEVDEELEEEEEEE---GEDKMKERKR 927
Score = 40.8 bits (94), Expect = 0.007
Identities = 34/145 (23%), Positives = 70/145 (48%), Gaps = 10/145 (6%)
Query: 840 EPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFET 899
+PE+ E+ ++ ++E+++D K +EE +E +E+ + +++ E +H
Sbjct: 177 DPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVA-----EILHHLVQRPE 231
Query: 900 DVLSSWRESAK--QGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTL 957
D L + K + T+ Q E MA EH + L+E+ N + AEE F ++L +
Sbjct: 232 DYLENVENIVKLYKETILQTLEEVMA--EHNPQYLIEL-NGNKPAEELFMIVMDRLKYLN 288
Query: 958 IKNKDLEELVMTSRKESKEEKENQD 982
+K + + + +E + EN +
Sbjct: 289 LKRAAILTKLQGAEEEINDTMENDE 313
Score = 40.0 bits (92), Expect = 0.011
Identities = 73/308 (23%), Positives = 122/308 (39%), Gaps = 50/308 (16%)
Query: 735 EKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNS-HKNATEDLYEVD 793
EK + GV +E + + Y S + T A +KS N H A + +
Sbjct: 479 EKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDG 538
Query: 794 KLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEA-----VKEFIEPEIDESFK 848
K E + + ++K T T + IE + + ++E I+ D +F+
Sbjct: 539 KETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFE 598
Query: 849 EDEEESKEDRK-----LQEENKERAEEQP--------STSTEKE------------KLIR 883
+ E+ E + + EENK+R P + KE L+
Sbjct: 599 QPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVI 658
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
++ + EN + K LF L K+ + K LE + +E +Q+K E E + E
Sbjct: 659 YLSDTEN-NGKCLFNRIYLQ------KKSEIDSKILERL--LEELQKKKKEEEEARKATE 709
Query: 944 EKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEE-EQQEEEEVRSAE 1002
E+ E N+ L EL+ KE+ EE +N+DE E++ +E E EE E
Sbjct: 710 EELRLEEE--------NRRLLELMKVKAKEA-EETDNEDEEEIEGDELEVHEEPEASHDT 760
Query: 1003 NSSKSPKK 1010
S P++
Sbjct: 761 RGSWLPEE 768
Score = 39.7 bits (91), Expect = 0.014
Identities = 52/213 (24%), Positives = 90/213 (42%), Gaps = 39/213 (18%)
Query: 831 EEEAVKEFIEPEIDESFKEDEEESKEDRKLQEEN-------------KERAEEQPSTSTE 877
EEE E E+DE +E+EEE ED+ + + KE QP + E
Sbjct: 894 EEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEE 953
Query: 878 ----KEKLIRFIG-----------EDENVHSKPLFETDV---LSSWRESAKQGTLAQKYL 919
+EK+ F ED H +PL + L + S K T+ + L
Sbjct: 954 AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGK--TMCGRQL 1011
Query: 920 EAMAVIEHMQEKLLEVENRARQAEEKFEDAYEK-LHHTLIKNKDLEELVMTSRKESKEEK 978
I H+Q + + E + E+K +E+ + ++LEEL + + + +EE
Sbjct: 1012 AEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEE- 1070
Query: 979 ENQDEREVKEEEEQQEEEEVRSA--ENSSKSPK 1009
++++ E + +EEE ++S+ EN P+
Sbjct: 1071 --NTKKQLPEVQLTEEEEVIKSSLMENEPLPPE 1101
Score = 32.7 bits (73), Expect = 1.8
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 967 VMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAE 1002
V+ + ++ K+E + + E +EEEE+QEEEE AE
Sbjct: 180 VIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAE 215
Score = 31.6 bits (70), Expect = 3.9
Identities = 14/32 (43%), Positives = 22/32 (68%)
Query: 965 ELVMTSRKESKEEKENQDEREVKEEEEQQEEE 996
E++ RK+ KE +++ E +EEEEQ+EEE
Sbjct: 179 EVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
Score = 31.2 bits (69), Expect = 5.2
Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 8/91 (8%)
Query: 916 QKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESK 975
+K LE +I+ M+ K+ V+ A++ E + +K +++ D EE+ E +
Sbjct: 1173 KKKLERKKLIKDMKAKI-RVDTIAKRRAELILERDKKRRENVVR--DDEEI-----SEEE 1224
Query: 976 EEKENQDEREVKEEEEQQEEEEVRSAENSSK 1006
E++N D + E+E ++EEE+ E+ +
Sbjct: 1225 LEEDNDDIENILEDEFPKDEEEMSGEEDEEQ 1255
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 58.5 bits (140), Expect = 3e-08
Identities = 202/1047 (19%), Positives = 409/1047 (39%), Gaps = 145/1047 (13%)
Query: 15 STSESKKLKVSVAKEGTRGLPELKEKKNMVDRSK---LLPTSLQNEFIPKEVLLSLTYAA 71
ST +KK +E + + E+KEK +SK +L +N+ + EV +
Sbjct: 1652 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPA---GD 1708
Query: 72 NAGPCPENLLPPKKIKTPKGTLPRLVDHVWHHPVRRNKFKYLIDHPVSLTGAGRDISFLY 131
A C E LL + K L R+ + KF+ L+ SL+ +D+
Sbjct: 1709 TAKECMETLLSSNA--SMKEELERVK---MEYETLSKKFQSLMSEKDSLSEEVQDLKHQI 1763
Query: 132 DVTYAK-----------GQTREKAVCPPHLARSLQSHDGVIVPHKPKTLTDTLIPEEFHI 180
+ +K QT + + D + + +P + +
Sbjct: 1764 EGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANP 1823
Query: 181 VSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQ 240
S S + ++ Y + + R+ K + L + +T+L + ++
Sbjct: 1824 AVSKDFSSHDEINN-YLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDG 1882
Query: 241 EYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVS-----VDCADRGELLSKVRERYVQML 295
E L +L++E T N++ ++ ++S + A+ E + ER + L
Sbjct: 1883 E----------LKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE--EEKDDLEERLMNQL 1930
Query: 296 DQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAH 355
++ + ++ +D+ ++ ++ + E+ N K + EL E + K+ E K +
Sbjct: 1931 AELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1990
Query: 356 KDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERN 415
+ Q N +E +L +++ ++ K + ++ S+ E +K +E
Sbjct: 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISAL--ERTVKALEFV 2048
Query: 416 RVILARRLYLNEKGWNKYTKH----------FIILLSNKDTEDLALLQKLTQKWRNLVNK 465
+ + L + ++ + +H F +LL + +E +L NL K
Sbjct: 2049 QTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLAD------NL--K 2100
Query: 466 LKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNE 525
LK+E++ +ES +K + L + E EK + K N+ LD + +K+
Sbjct: 2101 LKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHL--KEKKNMQEK--LDALRREKV--- 2153
Query: 526 KKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQ 585
EE G++ ++ K ++ LQEN + KS+ + ++E K +
Sbjct: 2154 HLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWER 2213
Query: 586 KLY-----KEYEIRINGDNGYSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKIN 640
K KE EIR+ DN L L S +E L+ + LE D++I
Sbjct: 2214 KFSDAIQSKEEEIRLKEDN-----CSVLKDQLRQMSIHMEELKINISRLEH----DKQIW 2264
Query: 641 EMKSHLDILLNLTGI-VPQHIDVDSVSVLQA--YIFNMIQQWLLKIGNEINNGNIELQHH 697
E K+ ++ L Q + + +S L+ ++++ Q L K+ +E+ + L+
Sbjct: 2265 ESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKS----LKDQ 2320
Query: 698 MDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELD---AIELTRK 754
+ +L N L + + +++ +E + +LE D + ELT +
Sbjct: 2321 LTDLS--------NSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSR 2372
Query: 755 LYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIK 814
L++ + + ++ K E + DK KE L N
Sbjct: 2373 LHEEINMKEQ----KIISLLSGKEEAIQVAIAELRQQHDKEIKE-----------LEN-- 2415
Query: 815 GRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPST 874
LL+ EE E ++ EE K+ ++ + ++ + + KE+ + + + + S
Sbjct: 2416 -----LLSQEEEENIVLEEENKKAVD-KTNQLMETLKTIKKENIQQKAQLDSFVKSMSSL 2469
Query: 875 STEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLE 934
++++++ + E H + E D L +E+A + ++ + + HM + L
Sbjct: 2470 QNDRDRIVGDYQQLEERHLSIILEKDQLI--QEAAAENNKLKEEIRGLR--SHMDD--LN 2523
Query: 935 VENRARQAEE-----------KFEDAYEK--LHHTLIKNKDLEELVMTSRKESKEEKE-N 980
EN AE +D+ +K L L +NK+LE ++ KE +E N
Sbjct: 2524 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEAN 2583
Query: 981 QDER---EVKEEEEQQEEEEVRSAENS 1004
+D R +EE+Q +E+ S + S
Sbjct: 2584 EDLRRSFNALQEEKQDLSKEIESLKVS 2610
Score = 52.8 bits (125), Expect = 2e-06
Identities = 142/759 (18%), Positives = 301/759 (39%), Gaps = 126/759 (16%)
Query: 293 QMLDQIARQMIDFYK-DLVTQRVMDQRILEELYNFKHVIEELT----------------R 335
++ QI ++F+K + ++ +D++ +E+ N +IEE R
Sbjct: 688 RLKSQILELELNFHKAQEIYEKNLDEKA-KEISNLNQLIEEFKKNADNNSSAFTALSEER 746
Query: 336 ELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEE----YHDLYTLQRERMENDMK 391
+ L + ++ + E K L L AE+ ++ E + +L T Q + + K
Sbjct: 747 DQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAK 806
Query: 392 KLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGW------------NKYTKHFII 439
+ ++ + ++ L+ E++ +I + + L K + +
Sbjct: 807 SKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ 866
Query: 440 LLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKD 499
LS K+ E + Q L +K R+ V L+Q +E+ ++ +E + + +++ E EK
Sbjct: 867 ALSQKELEITKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMTEKMVQLNE---EKF 922
Query: 500 ILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGI 559
L ++ K ++ LN LLS+ + K + ++N GL
Sbjct: 923 SLG-----------VEIKTLKEQLN----------LLSRAEEAKKEQVEEDNEVSSGL-- 959
Query: 560 FNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKL 619
++ + P+ + EE+ L KE E R K+ +LI+ + ++
Sbjct: 960 ---KQNYDEMSPAGQISKEELQHEFDLLKKENEQRKR------KLQAALINRKELLQ-RV 1009
Query: 620 ENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQQW 679
LE +E+ +E K + + G V + D ++ + + + Q+
Sbjct: 1010 SRLE---------EELANLKDESKKEIPLSETERGEVEE--DKENKEYSEKCVTSKCQEI 1058
Query: 680 LLKIGNEINNGNIELQHHMDELHISM-----IQWMVNLLILMIPNFTDQDCLLKLE--EE 732
+ + I+ +ELQH +L + Q +V + + + T+Q LL+ E E
Sbjct: 1059 EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISEN 1118
Query: 733 SAEKHDIGVARLEL---DAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDL 789
A + + + D++ L ++ + +S C G S + E +
Sbjct: 1119 QAIIQKLITSNTDASDGDSVALVKE----TVVISPPCTG--------SSEHWKPELEEKI 1166
Query: 790 YEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEF-----IEPEID 844
++K K++ + + + RK L +E ER L EE ++ ++ + D
Sbjct: 1167 LALEKEKEQLQKKLQEA------LTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFD 1220
Query: 845 ESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENV-------HSKPLF 897
E KE+E + R+LQ + +E + + ++ ++E G +E + H++P+
Sbjct: 1221 EQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVL 1280
Query: 898 ETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTL 957
E+++ W ++ + L+ + ++ +L E+E + E K +L
Sbjct: 1281 ESNLCPDWPSHSEDASA----LQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKS 1336
Query: 958 IKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEE 996
+ L+E + E + K E EV E QQ+ E
Sbjct: 1337 EEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLE 1375
Score = 40.0 bits (92), Expect = 0.011
Identities = 170/873 (19%), Positives = 360/873 (41%), Gaps = 144/873 (16%)
Query: 221 VAQLNDVMDTMLERAGVENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADR 280
++ L D D +++ A ++++ + + LK++ + + +RQ+S+ +
Sbjct: 2194 MSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNC---SVLKDQLRQMSIHMEEL 2250
Query: 281 GELLSKVRERYVQMLDQIARQMIDFYKDLV-TQRVMDQRILEELYNFKHVIEELTRELCL 339
+S++ E Q+ + A+ + + + T + ++ +L +L +H+ EL
Sbjct: 2251 KINISRL-EHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELA- 2308
Query: 340 VRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDI 399
KL E K+ KD L N+ + K E+ +L + R++ E DI
Sbjct: 2309 ------KLESEL-KSLKDQLTDLSNSLEKCK--EQKGNLEGIIRQQ----------EADI 2349
Query: 400 WSSA-TYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQK 458
+S +YE ++ +R + +R L+E+ N + I LLS K+ + +L Q+
Sbjct: 2350 QNSKFSYEQLETDLQASRELTSR---LHEE-INMKEQKIISLLSGKEEAIQVAIAELRQQ 2405
Query: 459 W----RNLVNKLKQEVEQ---MEESTS----------ETLKIVKDGLIKWQEFFNEKDIL 501
+ L N L QE E+ +EE ETLK +K I+ + +
Sbjct: 2406 HDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKS 2465
Query: 502 SPNKGNIFNSVLLDFKQWQK----ILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGL 557
+ N + ++ D++Q ++ I+ EK ++ + + I+ L+ + D+
Sbjct: 2466 MSSLQNDRDRIVGDYQQLEERHLSIILEK-DQLIQEAAAENNKLKEEIRGLRSHMDDLN- 2523
Query: 558 GIFNRHKSLEGEMPSERQYMEEIIK---NIQKLYKEYEIRINGD--NGYSKILPSLISSL 612
+ + L+ E+ R+ + ++I + QK E +++ N + N Y+K+ L S
Sbjct: 2524 ---SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESE 2580
Query: 613 DFCSFKLENLEFPDTPL-EEWQEIDEKINEMKSHLDILLNLTGIVPQH-----------I 660
+ E+L L EE Q++ ++I +K + L + + +
Sbjct: 2581 E----ANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKV 2636
Query: 661 DVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNF 720
+ V L A +F+ Q+ + ++ E+ E + E+ + + + +L
Sbjct: 2637 KEEEVHRLSA-LFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHL-------- 2687
Query: 721 TDQDC-LLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVT-AMALSKS 778
D +++ E E+AE+ VA L D +E+ +KL + + + ++S
Sbjct: 2688 -HHDAGIMRNETETAEER---VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSL 2743
Query: 779 TNSHKNATEDLYEVDK-----------------LKKECYEWINTCSCLLSNIKGRKITLL 821
NS +A E+L E+ + L +E ++ + +++ + ++ L
Sbjct: 2744 QNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHL 2803
Query: 822 TYEEI-ERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQ----------------EEN 864
E++ ++LL ++ + ++++S+ + + SK LQ EE
Sbjct: 2804 --EKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEG 2861
Query: 865 KERAEEQPSTS-TEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQ--------GTLA 915
K+R+ QPSTS E + L + + +N + L E L Q
Sbjct: 2862 KQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQL 2921
Query: 916 QKYLEAMAVIEHMQEKLLEVENRARQAE---EKFEDAYEKLHHTLIKNKDLEELVMTSRK 972
Q+Y + + MQE+L + EN + Q E + E + ++H +K + L+ S K
Sbjct: 2922 QEYQDKTKAFQIMQEELRQ-ENLSWQHELHQLRMEKSSWEIHERRMKE---QYLMAISDK 2977
Query: 973 ESKEEKENQDEREVKEEEEQQEEEEVRSAENSS 1005
+ + RE++ Q + +V+ +S
Sbjct: 2978 DQQLSHLQNLIRELRSSSSQTQPLKVQYQRQAS 3010
Score = 38.1 bits (87), Expect = 0.042
Identities = 69/349 (19%), Positives = 144/349 (41%), Gaps = 42/349 (12%)
Query: 676 IQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAE 735
+Q+ + K G EI + ++ H E+H +Q + L I + L +L+ + E
Sbjct: 1342 LQEQINKQGLEIES--LKTVSHEAEVHAESLQQKLESSQLQIAGL---EHLRELQPKLDE 1396
Query: 736 KHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKL 795
+ +++ E D L+ +L + + L+ ++ L K+ ++ +++
Sbjct: 1397 LQKL-ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHT---------QLEMQ 1446
Query: 796 KKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESK 855
KE E I L +K ++ E + EE K+ I+ ++ + +E K
Sbjct: 1447 AKEHDERIKQLQVELCEMK---------QKPEEIGEESRAKQQIQRKLQAALISRKEALK 1497
Query: 856 EDRKLQEE-----------NKERAEEQPSTST---EKEKLIRFIGEDENVHSKPLFETDV 901
E++ LQEE K A+ + S EK+ ++ + + K + E D
Sbjct: 1498 ENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD- 1556
Query: 902 LSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNK 961
S E+ + + A+ + +EKL++ + ++ +++ H L K
Sbjct: 1557 -RSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKEL--QK 1613
Query: 962 DLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
+ E L+ + S E + Q E +E+Q+ ++RS E + K +K
Sbjct: 1614 EYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEK 1662
Score = 36.6 bits (83), Expect = 0.12
Identities = 52/290 (17%), Positives = 112/290 (38%), Gaps = 56/290 (19%)
Query: 775 LSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEA 834
LS++ + K E+ EV K+ Y+ ++ + + LL E +R + +A
Sbjct: 938 LSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQA 997
Query: 835 V----KEFIE--PEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGED 888
KE ++ ++E ++ESK++ L E + EE EK + ++
Sbjct: 998 ALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQE 1057
Query: 889 ENVHSKP-LFETDV-LSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKF 946
++ K + E +V L R+ ++ A++ +A+ ++ M + L + N+ + +
Sbjct: 1058 IEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL--VKQMNQTLQDKTNQIDLLQAEI 1115
Query: 947 EDAYEKLHHTLIKNKD------------------------------LEELVMTSRKESKE 976
+ + + N D LEE ++ KE ++
Sbjct: 1116 SENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQ 1175
Query: 977 ----------------EKENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
+K + ER ++EE +QQ+++ R E + K+
Sbjct: 1176 LQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE 1225
Score = 33.1 bits (74), Expect = 1.4
Identities = 46/192 (23%), Positives = 80/192 (41%), Gaps = 22/192 (11%)
Query: 825 EIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRF 884
++E L + + KE ++D+ E + + + ++ EE ++ E + TEK +
Sbjct: 860 KVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE 919
Query: 885 IGEDENVHSKPLFETDVLSSWRESAKQ----------GTLAQKYLEAMAVIEHMQEKLLE 934
V K L E L S E AK+ L Q Y E + +E E
Sbjct: 920 EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKE---E 976
Query: 935 VENRARQAEEKFEDAYEKLHHTLIKNKDL-------EELVMTSRKESKEE--KENQDERE 985
+++ +++ E KL LI K+L EE + + ESK+E + E
Sbjct: 977 LQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGE 1036
Query: 986 VKEEEEQQEEEE 997
V+E++E +E E
Sbjct: 1037 VEEDKENKEYSE 1048
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 58.2 bits (139), Expect = 4e-08
Identities = 145/714 (20%), Positives = 278/714 (38%), Gaps = 135/714 (18%)
Query: 321 EELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYT 380
E L + IE+L E L RA K T + ++LA A + HD +
Sbjct: 355 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA-----------RDGHDQHV 403
Query: 381 LQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIIL 440
L+ E + ++ +V D EL ++ E R + + + E+ K
Sbjct: 404 LELEAKMDQLRTMVEAAD---REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTK 460
Query: 441 LSN---KDTEDLALLQKLTQKWRNLVNKLKQEVEQMEEST----SETLKIVKDGLIKWQE 493
L + K+ E L +K +KL++E+E +T S +++ KD ++ QE
Sbjct: 461 LEHARIKELEQSLLFEKTK------ADKLQRELEDTRVATVSEKSRIMELEKDLALRVQE 514
Query: 494 FFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWA 553
+ L NK + L Q L EK E +++ D + I L+E++
Sbjct: 515 VAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLE-------VTRTDHQREITSLKEHFG 567
Query: 554 DIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNG------YSKILPS 607
R ++ + E+ + E++ K + L + E N +N SK+ +
Sbjct: 568 A-------REETHQKEIKALYTATEKLSKENESLKSKLE-HANKENSDVIALWKSKLETA 619
Query: 608 LISSLDFCS-FKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVS 666
+ S K+ + T E+ E+ +I +M+ LD + + Q DS
Sbjct: 620 IASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMR--LDYQHEIENLQNQQ---DSER 674
Query: 667 VLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCL 726
A ++ L+K+ E N ++ +D+ + M +D L
Sbjct: 675 AAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEM-------------EDTL 721
Query: 727 LKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNAT 786
KL+E + ++ V L+ E T+ + ++S L + + ++ AL K+++ K+
Sbjct: 722 NKLQEAEIKVKELEV--LQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEM 779
Query: 787 EDLYE--------VDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEF 838
+ L + + L+ E + S + ++GR++ L +E L E VKE
Sbjct: 780 KKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE--NLSEVSQVKET 837
Query: 839 IEPEID---ESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKP 895
+E E+ E F E EE+ ++ +E + + KE+ + D
Sbjct: 838 LEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQ-------KEEQFNMLSSD------- 883
Query: 896 LFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFED---AYEK 952
+E ++E L ++E + R+ +E+ E A EK
Sbjct: 884 -----------------------------LEKLRENLADMEAKFREKDEREEQLIKAKEK 914
Query: 953 LHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEE-EQQEEEEVRSAENSS 1005
L + D+ E++ S S + + DE +KE + E+ + + ++ EN+S
Sbjct: 915 LEN------DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 962
Score = 46.6 bits (109), Expect = 1e-04
Identities = 153/778 (19%), Positives = 296/778 (38%), Gaps = 115/778 (14%)
Query: 319 ILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDL 378
+L +L K +E+L R + +TK + L A + E ++ E
Sbjct: 427 LLNQLEEEKRKVEDLQ-----FRVEEESITKGDLETQTKLEHARIK-ELEQSLLFEKTKA 480
Query: 379 YTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFI 438
LQRE +E+ V+E+ +LAL+V E L RRL N+ +
Sbjct: 481 DKLQRE-LEDTRVATVSEKSRIMELEKDLALRVQEVAE--LRRRLESNKPAGD------- 530
Query: 439 ILLSNKDTEDLALLQKLTQKWRN----LVNKLKQEVEQMEESTSETLKIV---KDGLIKW 491
+ +S ++++ LQ+ + R + LK+ EE+ + +K + + L K
Sbjct: 531 VDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKE 590
Query: 492 QEFFNEKDILSPNKGNIFNSVLLDFK------QWQKILNEKKEEFTGDVLLSKYDTLKII 545
E K + NK N L K Q+ + E K F+ + + ++
Sbjct: 591 NESLKSK-LEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELK 649
Query: 546 KHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYE-----IRINGDNG 600
+++ D I N + E + + ME + + K+ KE E IR D
Sbjct: 650 TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKA 709
Query: 601 YSKILPSL---ISSLDFCSFKLENLEFPDTPL-EEWQEIDEKINEMKSHLDILLNLTGIV 656
+ L + ++ L K++ LE E+ + ID +++K+ + LL+L +
Sbjct: 710 EDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALR 769
Query: 657 PQHIDVDSV-----SVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVN 711
+ S L+A + + K +I + EL ++ +Q ++
Sbjct: 770 KASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLS 829
Query: 712 LLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVT 771
+ + + +LK + A + + V R + + + + + LSS + +
Sbjct: 830 EVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRE 889
Query: 772 AMALSKSTNSHKNATED--LYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERL 829
+A ++ K+ E+ + +KL+ + E + + G + LT E
Sbjct: 890 NLADMEAKFREKDEREEQLIKAKEKLENDIAE--------IMKMSGDNSSQLTKMNDELR 941
Query: 830 LEEEAVKE-------------FIEPEIDE------------SFKEDEEESKEDRKLQEEN 864
L+E V+E F++ I++ + K +EE+ + +RKL +
Sbjct: 942 LKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE 1001
Query: 865 KERAEEQPSTSTEKEKLIRFIGEDENVH-------SKPLFETD---------------VL 902
K+ K + R E + H K L +T+ L
Sbjct: 1002 KKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQEL 1061
Query: 903 SSWRESAKQGTLAQKYLEAMAVIEHM----QEKLLEVENRARQAEEKFEDAYEKLHHTLI 958
R+ A + AQ +AM ++E M E L +E+ +Q K ++ + L +
Sbjct: 1062 EELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLED-TKQTNAKLQNELDTLKENNL 1120
Query: 959 K-----NKDLEELVMTSRKESKEEKENQDEREVKEEEEQQ----EEEEVRSAENSSKS 1007
K NK E L + ++K + KE + ++ ++ QQ +EE V+ AE +S
Sbjct: 1121 KNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRS 1178
Score = 40.0 bits (92), Expect = 0.011
Identities = 149/812 (18%), Positives = 317/812 (39%), Gaps = 115/812 (14%)
Query: 220 EVAQLNDVMDTMLERAGVENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCAD 279
++++ N+ + + LE A EN + K KL + Q + + + + A+
Sbjct: 586 KLSKENESLKSKLEHANKENSDVIALWKS-KLETAIASHQQAMEELKVSFSKGLGTETAE 644
Query: 280 RGEL---LSKVRERYVQMLDQIARQMID----FYKDLVTQRVMDQRILEELYNFKHVIE- 331
EL + K+R Y ++ + Q K++ R ++++E N I
Sbjct: 645 FAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRS 704
Query: 332 --ELTRELCLVRAHD-VKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMEN 388
+ + LV D + +E E K+L + K++ D +T Q + E
Sbjct: 705 KLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVI----DNFTSQLKATEE 760
Query: 389 DMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTED 448
+ L A R S E+ ++L + K KH I + + ++
Sbjct: 761 KLLDLDALRKASSEGKSEM-------------KKLRQQLEAAEKQIKHLEIEKNAESSKA 807
Query: 449 LALLQKLTQKWRNLVNKLKQ--EVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKG 506
++ ++L + L N + EV Q++E+ + L+I+K+ K+ E E
Sbjct: 808 SSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKE---KFAEASEEAV------- 857
Query: 507 NIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSL 566
SV ++ L++K+E+F +LS ++ L+EN AD+ F
Sbjct: 858 ----SVQRSMQETVNKLHQKEEQFN---MLSSD-----LEKLRENLADMEAK-FREKDER 904
Query: 567 EGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKL-ENLEFP 625
E ++ ++ +E I I K+ + ++ N ++ + L K EN F
Sbjct: 905 EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFL 964
Query: 626 DTPLEEW--------QEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQ 677
+E+ QE +K E K L+ L+ + N Q
Sbjct: 965 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS------------DLEKKMETSHNQCQ 1012
Query: 678 QWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKH 737
+ + + + + + L +++ L N L +LEE +
Sbjct: 1013 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREEN---SGLLQELEELRKQAD 1069
Query: 738 DIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKK 797
A+ DA+++ ++ + + + ++ +K TN+ D + + LK
Sbjct: 1070 KAKAAQTAEDAMQIMEQMTKEKTET-------LASLEDTKQTNAKLQNELDTLKENNLKN 1122
Query: 798 ECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKED 857
E +N LL+ +E + ++EF EI+ + ++S++
Sbjct: 1123 --VEELNKSKELLT------------------VENQKMEEF-RKEIETLKQAAAQKSQQL 1161
Query: 858 RKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSS--WRESAKQGTLA 915
LQEEN + AEE S ++ + + E+ +V + L E S +++ ++
Sbjct: 1162 SALQEENVKLAEEL-GRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1220
Query: 916 QKYLEAMAVIEHMQEKLLEVEN-RARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKES 974
QK + + + + EK E+E R + E+A K H++++ + +++ + + ++
Sbjct: 1221 QKSISITSAL--LTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKN 1278
Query: 975 KEEKENQDEREVKEEE---EQQEEEEVRSAEN 1003
E + +++R++ + Q +E+ R+ E+
Sbjct: 1279 LELQLKENKRQLSSSSGNTDTQADEDERAQES 1310
Score = 38.1 bits (87), Expect = 0.042
Identities = 75/368 (20%), Positives = 152/368 (41%), Gaps = 54/368 (14%)
Query: 195 KYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLER-----AGVENQEYTGPTKMH 249
K +++ + + R L +++ N EV+Q+ + ++ L+ A + + M
Sbjct: 806 KASSITRELQGRELKLTNLQENLS-EVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQ 864
Query: 250 KLLHILKKEQTIYNMIFHEL--IRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFYK 307
+ ++ L +++ +NM+ +L +R+ D + + E+ ++ +++ + + K
Sbjct: 865 ETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 924
Query: 308 DLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKA---HKDLAQALLN 364
++ +EL + +EEL +KLTK E A K + +
Sbjct: 925 MSGDNSSQLTKMNDELRLKERDVEEL----------QLKLTKANENASFLQKSIEDMTVK 974
Query: 365 AEKNAKIVEEYHDLYTLQRERMENDMKKLVAE--------RDIWSSATYELALKVIERNR 416
AE++ + + H+ + ER +D++K + + + AT E K E +
Sbjct: 975 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 1034
Query: 417 VILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLK--------- 467
+ L +K L E+ LLQ+L ++ R +K K
Sbjct: 1035 NLQKTLLDTEDK------------LKGAREENSGLLQEL-EELRKQADKAKAAQTAEDAM 1081
Query: 468 QEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFN-SVLLDFKQWQKILNEK 526
Q +EQM + +ETL ++D + NE D L N N+ N L K+ + N+K
Sbjct: 1082 QIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKEN--NLKNVEELNKSKELLTVENQK 1139
Query: 527 KEEFTGDV 534
EEF ++
Sbjct: 1140 MEEFRKEI 1147
Score = 37.7 bits (86), Expect = 0.055
Identities = 39/169 (23%), Positives = 70/169 (41%), Gaps = 26/169 (15%)
Query: 843 IDESFKEDEEESKEDRKLQEENKERAEEQPSTS----TEKEKLIRFIGEDENVHSKPLFE 898
+ E+ KE ++ ++ L E + ERAE +TS E+E + G D++V
Sbjct: 353 LQEALKEKQQHIEQ--LLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLE----- 405
Query: 899 TDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLI 958
L K + ++E + +E+ N+ + + K ED ++ I
Sbjct: 406 ---------------LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESI 450
Query: 959 KNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKS 1007
DLE KE +++ + K ++ Q+E E+ R A S KS
Sbjct: 451 TKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKS 499
Score = 32.3 bits (72), Expect = 2.3
Identities = 46/206 (22%), Positives = 89/206 (43%), Gaps = 24/206 (11%)
Query: 823 YEEIERLLEEEAVKEFIEPEIDESFKEDEE-----ESKEDRKLQEENKERAEEQPSTS-- 875
Y E+L +E E ++ +++ + KE+ + +SK + + + E + S S
Sbjct: 581 YTATEKLSKEN---ESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKG 637
Query: 876 --TEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEA-----MAVIEHM 928
TE + + E + E + L + ++S + K +EA M VI+
Sbjct: 638 LGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHA--KEMEALRAKLMKVIKEK 695
Query: 929 QEKLLEVENRARQAEEK----FEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDER 984
+ L + ++ +AE++ ED KL IK K+LE L +++K +N +
Sbjct: 696 ENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTK-VIDNFTSQ 754
Query: 985 EVKEEEEQQEEEEVRSAENSSKSPKK 1010
EE+ + + +R A + KS K
Sbjct: 755 LKATEEKLLDLDALRKASSEGKSEMK 780
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 57.4 bits (137), Expect = 7e-08
Identities = 77/310 (24%), Positives = 126/310 (40%), Gaps = 59/310 (19%)
Query: 723 QDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYL--------SSCCKGMVTAMA 774
+D +L +EE K + R + ++ RKL + S L K A
Sbjct: 2020 EDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKA 2079
Query: 775 LSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIK------GRKITLLTYEEIER 828
L K T + T++ ++ K+K+ + S S + K + LT +E +
Sbjct: 2080 LQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKL 2139
Query: 829 LLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGED 888
++ + + I++ K EEESK RK E + EE E+E++I F+
Sbjct: 2140 ARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEG---GIEEEEVIPFLKR- 2195
Query: 889 ENVHSKPLFETDVLSSWRE--SAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKF 946
WR+ AK+G + E ++ EVE+ EE F
Sbjct: 2196 ---------------RWRKRKEAKRGDKPK---------EKFSSQVDEVES-----EEHF 2226
Query: 947 EDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEE------VRS 1000
+ E L L K + L + +E +EE+E ++E EV+EEEE+++EEE V
Sbjct: 2227 SEEMESLLDELEKQESLS----SEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282
Query: 1001 AENSSKSPKK 1010
E K KK
Sbjct: 2283 EEEEKKKKKK 2292
Score = 53.5 bits (127), Expect = 1e-06
Identities = 142/719 (19%), Positives = 287/719 (39%), Gaps = 91/719 (12%)
Query: 317 QRILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYH 376
+++ EE E L +E + H K+ +E E+ + Q + EK K+ ++
Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLI---EKKMKLAQK-- 1815
Query: 377 DLYTLQRERMENDMKKLVAERDI-WSSATYELALKVIERNRVILARR----LYLNEKGWN 431
RER N M++L + I + K + + + LA+R LY E+
Sbjct: 1816 ------RERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKER--L 1867
Query: 432 KYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKI---VKDGL 488
++K ++ + NK L + K+ + + + K+ V + +E +ET K V+D L
Sbjct: 1868 THSKKQLVQVKNK----LGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923
Query: 489 IKWQE-FFNEKDILSPNKGNIFNSVLL----DFKQWQKILN--------EKKEEFTGDVL 535
K QE EK L+ K + L D + +K LN EK G
Sbjct: 1924 AKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKET 1983
Query: 536 LSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYM-----EEIIKNIQKLYKE 590
LSK +T + + Q + +F R SLE ++ + EI K + +
Sbjct: 1984 LSKGETPETSR--QRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRG 2041
Query: 591 YEIRINGDNGYSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILL 650
I + G +K LI + S + L L++ + K+ + + + +
Sbjct: 2042 QRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMK 2101
Query: 651 NLTGIVPQHIDVDSVSV-LQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWM 709
+ + + ++ + ++ + F+ + L K ++ +L + M M
Sbjct: 2102 RALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRR--------M 2153
Query: 710 VNLLILMIPNFTDQDCLLKLEEESAEKH-DIGVARLELDAIELTRKLYQYSSYLSSCCKG 768
+N ++ + + E + A KH ++ + E IE + +L +
Sbjct: 2154 IN----------KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVI----PFLKRRWRK 2199
Query: 769 MVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIER 828
A K + +++ + +E LL ++ ++ +L + EE ER
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEM-------ESLLDELEKQE-SLSSEEEEER 2251
Query: 829 LLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTST-EKEKLIRFIGE 887
EEE +E + E +E +E+E E K+ K +EE K++ +E+ EKE++ E
Sbjct: 2252 EEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE---E 2308
Query: 888 DENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVI-EHMQEKLLEVENRARQAEEKF 946
E + S+ ET+ LS E + +L ++ ++ + Q KL E ++ + E+
Sbjct: 2309 KEEIMSEE--ETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366
Query: 947 EDAYEKLHHTL-------IKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEV 998
+ H + L++L+ T+ + ++ E+++ E+++ E+
Sbjct: 2367 LSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKKATVVEI 2425
Score = 52.0 bits (123), Expect = 3e-06
Identities = 52/204 (25%), Positives = 105/204 (51%), Gaps = 22/204 (10%)
Query: 810 LSNIKGRKITLLTYEEIERLLEEEAVKEFIEP---EIDESFKEDEEESKEDRKLQEENKE 866
+ NI +K+ L E +E+ + + +E +++E ++EE ++E+ KL EE K+
Sbjct: 1689 VKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKK 1748
Query: 867 RAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIE 926
AEE+ + + ++EKL E+E +K E ++L +E Q +K E +
Sbjct: 1749 LAEEEEALAWQREKL----SEEE---TKLAQEEELLIQEKEKLAQH--KEKMPEEEERLG 1799
Query: 927 HMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREV 986
+E+L+E + + Q E++ ++ E+ L KNK +++ +K +EK+N +
Sbjct: 1800 RKREQLIEKKMKLAQKRERWINSMEE----LTKNK----MILYQKKNLAQEKKNLAQE-- 1849
Query: 987 KEEEEQQEEEEVRSAENSSKSPKK 1010
KE+ Q++E + + E + S K+
Sbjct: 1850 KEKLAQRKENLLYNKERLTHSKKQ 1873
Score = 47.8 bits (112), Expect = 5e-05
Identities = 47/208 (22%), Positives = 97/208 (46%), Gaps = 18/208 (8%)
Query: 814 KGRKITLLTYEEI---ERLLEEEAVKEFIEPEID--ESFKEDEEESKEDRKLQEENKERA 868
KG+K+ L + + + ++E K F + ++ +++ + K R++ +E ++ +
Sbjct: 1369 KGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMS 1428
Query: 869 EEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHM 928
EE +T +EK+++ G+ + P ++ D +W E + +K +A E
Sbjct: 1429 EEVEEMATLEEKVVKQEGKLVMIERTPSWQ-DWKKAWDEWKQVHGETRKSWKAWK--EEW 1485
Query: 929 QEKLLEVENRARQAEEKFEDAYEKLHH-TLIKNKDLEELVMTSRKESKEEKENQDEREVK 987
+++LL+ E + QA EK E L +K ++ +++ +E++ +DE EV
Sbjct: 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVT 1545
Query: 988 ---------EEEEQQEEEEVRSAENSSK 1006
EE+EQQ EE R + K
Sbjct: 1546 LEEEVSREGEEKEQQVTEEQRHIQEEHK 1573
Score = 44.3 bits (103), Expect = 6e-04
Identities = 71/257 (27%), Positives = 110/257 (42%), Gaps = 50/257 (19%)
Query: 787 EDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDES 846
E L E KLK E EW +LS+ K ++ EE+ LEEE +E E E
Sbjct: 1508 EMLQEDKKLKWE--EWKQVWENMLSS-KSKEQQYKDEEEVT--LEEEVSREGEEKE---- 1558
Query: 847 FKEDEEESKEDRKLQEEN-------------KERAEEQPSTSTEKEKLI---RFIGEDEN 890
++ ++E R +QEE+ K+RA+E+ + E+EKL R + ++E
Sbjct: 1559 ----QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEER 1614
Query: 891 VHSKPLFETDVLSSWRESA--------KQGTLAQ---KYLEAMAVIEHMQEKLLEVENRA 939
++ + + RE A K+ TLAQ K + + ++KL + +
Sbjct: 1615 KLAQAYVK--ITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKV 1672
Query: 940 RQAEEKFEDAYEKLHHTLIKN---KDLEELVMTSRKESKEEKENQDEREVKE---EEEQQ 993
+ EEK KL +KN + +EEL + +EKE E E E EE
Sbjct: 1673 AREEEKLAKKGGKLAE--VKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSW 1730
Query: 994 EEEEVRSAENSSKSPKK 1010
+EEE+ E KK
Sbjct: 1731 KEEELNQEEGKLVEEKK 1747
Score = 39.7 bits (91), Expect = 0.014
Identities = 43/194 (22%), Positives = 85/194 (43%), Gaps = 11/194 (5%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
E + R E+ K+ + E + EE +++ + + K A+E+ + + EKEKL +
Sbjct: 1796 ERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQ 1855
Query: 884 -----FIGEDENVHSKPLFET--DVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVE 936
++ HSK + L + + Q + +K + + +EKL E E
Sbjct: 1856 RKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQ--VEEKLTQEKETVIKKKEKLAETE 1913
Query: 937 NRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKE-NQDEREVKEEEEQQEE 995
+ Q E+ EKL +K LE+ ++ +K + E + ++E+ + E ++ E
Sbjct: 1914 KKLVQVEDSLAKKQEKLAQEKMK-LALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAE 1972
Query: 996 EEVRSAENSSKSPK 1009
E++R E K
Sbjct: 1973 EKMRLVEGKETLSK 1986
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 57.4 bits (137), Expect = 7e-08
Identities = 52/207 (25%), Positives = 94/207 (45%), Gaps = 27/207 (13%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEEN--KERAEEQPSTSTEKEKL 881
EE ++ EEE +K E E +E E+ K +RK Q+E KER +++ T+ ++
Sbjct: 355 EERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414
Query: 882 IRFIGE----------------DENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVI 925
R E D +P++E + + +++ +E A +
Sbjct: 415 ARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES-MELCAAV 473
Query: 926 EHMQEKLLEVENRAR----QAEEKFEDAYEKLHHTLIKNKDLEEL----VMTSRKESKEE 977
E M++ + E E + EE EDA + +++ E++ V KE+ EE
Sbjct: 474 EVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEE 533
Query: 978 KENQDEREVKEEEEQQEEEEVRSAENS 1004
+E ++E E ++EE ++EEEE +E S
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGS 560
Score = 52.0 bits (123), Expect = 3e-06
Identities = 48/182 (26%), Positives = 80/182 (43%), Gaps = 18/182 (9%)
Query: 844 DESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIG--------------EDE 889
D SFK K+ K + E K+R EE+ KEK G E+E
Sbjct: 220 DASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEE 279
Query: 890 NVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDA 949
V SK +T V+ + E A+ T A+ E + ++K E E + ++ ++ A
Sbjct: 280 TVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKA 339
Query: 950 YEK-LHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSP 1008
K + L K K+ EE ++E +E + +E E K +EE++ E+E R + +
Sbjct: 340 TVKAMQEALAKLKEEEE---RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKE 396
Query: 1009 KK 1010
+K
Sbjct: 397 RK 398
Score = 47.0 bits (110), Expect = 9e-05
Identities = 41/169 (24%), Positives = 80/169 (47%), Gaps = 10/169 (5%)
Query: 845 ESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSS 904
E K DEE++K + ++E E ++ S E ++ E+E V SK +T V+ +
Sbjct: 239 ERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKF----EEETVKSKVTVDTGVIPA 294
Query: 905 WRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEK-LHHTLIKNKDL 963
E A+ T A+ E + ++K E E + ++ ++ A K + L K K+
Sbjct: 295 SEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEE 354
Query: 964 EELVMTSRKESKEEKENQDEREVKEEEEQ--QEEEEVRSAENSSKSPKK 1010
EE ++E +E + +E E K +EE+ ++E+ R + + ++
Sbjct: 355 EE---RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Score = 33.5 bits (75), Expect = 1.0
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 824 EEIERLLEEEAVKEFIE-PEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLI 882
EE E++ E K IE E E +E+EEE +ED + +EE +E E + S E+++ +
Sbjct: 513 EETEKV---EGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569
Score = 33.1 bits (74), Expect = 1.4
Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Query: 813 IKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESK-EDRKLQEENKERAEEQ 871
++G K+ + E++ EEE +E E E +ES +E+EEE + E + EE+++ ++E+
Sbjct: 518 VEGNKVHI----EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEK 573
Query: 872 PSTSTEKEKLIRFIGEDENVHS 893
S T +K + + D S
Sbjct: 574 DSGKTLDKKPSKEMSSDSEYDS 595
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 57.0 bits (136), Expect = 9e-08
Identities = 164/827 (19%), Positives = 332/827 (40%), Gaps = 111/827 (13%)
Query: 197 TTLLTDSENRLLLFPSMKPNKRV---EVAQLNDVMDTMLERAGVENQEYTGPTKMHKLLH 253
TTL+ + + L ++K + QL M T ER+ V T+M +
Sbjct: 328 TTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVI------TRMKDRIG 381
Query: 254 ILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIA--RQMIDFYKDLV- 310
L+KE ++ H V + ++ K ++ QM +IA +Q +D V
Sbjct: 382 TLEKEHNVFQNKIH-------VSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVS 434
Query: 311 -TQRVMDQRILEEL----YNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNA 365
T ++ + EL ++ ++ ELT + ++ +V+ K E+A L L A
Sbjct: 435 NTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQ-KKNAEQAATQLKVQLQEA 493
Query: 366 EKNAKIVEEYHDLYTLQRERMENDMK-KLVAERDIWSSATYELALKVIERNRVILARRLY 424
E+ + V+ Y T + E + D++ K VA+ + S +L ++ + + + R +
Sbjct: 494 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQ-LEQRLMQ 552
Query: 425 LNEKGWNKYTKHFIILLSNKDT-EDLALLQKLTQKWRNLV------NKLKQEVEQMEEST 477
L E + K + + +D E L+ Q++ + + + L +E+ ++
Sbjct: 553 LMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEK 612
Query: 478 SETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLS 537
+ +K +D L ++ K+ + N+ + + ++ Q + NE+
Sbjct: 613 DKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQ----------- 661
Query: 538 KYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRING 597
A + +S+ + R E++ I +E++I
Sbjct: 662 ---------------AAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKIL--- 703
Query: 598 DNGYSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVP 657
N +K L S + L + N + + + QE DEK+ ++ L+ L +
Sbjct: 704 -NDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLET--GLIQVAT 760
Query: 658 QHIDVDSVSVLQAYIFNMIQQWLLKIGNEINNGNI--ELQH--HMDELHISMIQWMVNLL 713
+ +++++ + + +Q K ++++ ++ EL+ H + I ++ ++
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Query: 714 ILMIPNFTDQDCLLKLEEESAEKHDIGVARLE-LDAIELTRKLYQYSSYLSSCCKGMVTA 772
+L + N LK +E A K +IG +LE + +T K+ + + L KG
Sbjct: 821 LLKVANKEKTVQDLK-QEIKALKEEIGNVQLEKAQQLSITSKVQELQNLL----KGKEEQ 875
Query: 773 MALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEE 832
M K+ K +DL K ++ E + + + L E
Sbjct: 876 MNTMKAVLEEKE--KDLANTGKWLQDLQEENESLKAHVQEVAQHN-----------LKEA 922
Query: 833 EAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVH 892
+ +F E EI KE E E K +L+ KER + S K +L++ + +DEN
Sbjct: 923 SSASQFEELEI--VLKEKENELK---RLEAMLKERESDLSS----KTQLLQDV-QDEN-- 970
Query: 893 SKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEK 952
LF++ + +++ +Q + + E + VI ++++ + N + +DA E
Sbjct: 971 --KLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNEL----DSLKDAVE- 1023
Query: 953 LHHTLIKNKDLEELVMTSRKE-SKEEKENQDEREVKEEEEQQEEEEV 998
H KN DL E + + + EK QD+ +E QQ+ E V
Sbjct: 1024 --HQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAV 1068
Score = 53.5 bits (127), Expect = 1e-06
Identities = 167/792 (21%), Positives = 307/792 (38%), Gaps = 130/792 (16%)
Query: 278 ADRGELLSKVRE-RYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRE 336
++R L SK E + +Q ++ + + + + L ++ LE++ +V ++ R
Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684
Query: 337 LCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMEND----MKK 392
L H++ E K +LN ++N + E L TL E+ D M+K
Sbjct: 685 LEEQLQHEISNKMEEFK--------ILN-DQNKALKSEVQKLQTLVSEQPNKDVVEQMEK 735
Query: 393 LVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALL 452
+ E+D EL +E + +A + E+ N L K+ +DL
Sbjct: 736 CIQEKDEKLKTVEEL----LETGLIQVATK----EEELNAIRTENSSL--TKEVQDLKAK 785
Query: 453 QKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILS-PNKGNIFNS 511
Q + +LV +LK+ + + KDG IK E E ++L NK
Sbjct: 786 QNDQVSFASLVEELKKVIHE------------KDGKIKSVEELLEAELLKVANK----EK 829
Query: 512 VLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMP 571
+ D KQ K L E+ G+V L K L I +QE + N K E +M
Sbjct: 830 TVQDLKQEIKALKEE----IGNVQLEKAQQLSITSKVQE--------LQNLLKGKEEQMN 877
Query: 572 SERQYMEEIIKNI-------QKLYKEYE-IRINGDNGYSKILPSLISSLDFCSFKLENLE 623
+ + +EE K++ Q L +E E ++ + L S+ F E LE
Sbjct: 878 TMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQF-----EELE 932
Query: 624 FPDTPLE-EWQEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQ----- 677
E E + ++ + E +S L L V + + Q N Q
Sbjct: 933 IVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFP 992
Query: 678 --QWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEE---- 731
+ LLK+ +E L + +D L ++ L N+ + L E+
Sbjct: 993 PHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQD 1052
Query: 732 ---ESAEKHDIGVARLELDAIELTRKLY---------QYSSYLSSCCKGMVTAMALSKST 779
+++++ V +EL+A E+ +KL+ Y +L K MA + +
Sbjct: 1053 KVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGS 1112
Query: 780 NSHKNATEDLYEVDK----LKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAV 835
K L E D+ L+ EC ++ +L+ +G ++++R +E+E
Sbjct: 1113 EEVKVLEHKLKEADEMHTLLQLECEKY----KSVLAETEG------ILQKLQRSVEQEEN 1162
Query: 836 KEFIEPEIDESFKEDEE-------ESKEDRKLQEENKE-----RAEEQPSTSTEKEKLIR 883
K ++ +DES K ++ +E +L+ ENK+ R E EK ++ R
Sbjct: 1163 KWKVK--VDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMER 1220
Query: 884 FIGEDENVHSKPLF---ETDVLSSWRESAKQGT----LAQKYLEAMAVIEHMQEKLLEVE 936
E K L + + S+ E+ +Q L + E + + Q + +V
Sbjct: 1221 STYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVA 1280
Query: 937 NRARQAEEKFEDAYEKL-----HHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEE 991
+A++ E K+ T+I+N D+ +S KE+ NQ ++++ +
Sbjct: 1281 GDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQ 1340
Query: 992 QQEEEEVRSAEN 1003
++ + E+
Sbjct: 1341 AVNQQLTKEKEH 1352
Score = 37.0 bits (84), Expect = 0.094
Identities = 50/240 (20%), Positives = 106/240 (44%), Gaps = 39/240 (16%)
Query: 774 ALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEE 833
A+S +TN ++ + E++KL+++ +N + K L EE+++ E+
Sbjct: 432 AVSNTTNQLES--KQSAELNKLRQDYARLVNELT--------EKTGKLQQEEVQKKNAEQ 481
Query: 834 AVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHS 893
A + ++ ++ E+ + EE RK E++ ++ S KE E +++HS
Sbjct: 482 AATQ-LKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKEN------EVQSLHS 534
Query: 894 KPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFED----- 948
K TD L S ++ L Q+ ++ M E Q+++ + E+ Q ++ E
Sbjct: 535 KL---TDTLVSKQQ------LEQRLMQLM---ESEQKRVNKEESLQMQVQDILEQNEALK 582
Query: 949 -AYEKLHHTLIKNKDL----EELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAEN 1003
++ H + EEL ++ K+ K+ +D + + +EEE++ +N
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQN 642
Score = 35.4 bits (80), Expect = 0.27
Identities = 40/197 (20%), Positives = 85/197 (43%), Gaps = 23/197 (11%)
Query: 821 LTYEEIERL-LEEEAVKEFIEPEIDESFKED---------EEESKEDRKLQEENKERAEE 870
++Y+E +++ ++ + V+E +E EI +E+ E ++ E NK R +
Sbjct: 396 VSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDY 455
Query: 871 QPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYL-----EAMAVI 925
+ EK + E+ + T + +E+ ++ Q Y+ E A
Sbjct: 456 ARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQ 515
Query: 926 EHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDERE 985
+ +Q K + EN + K D TL+ + LE+ +M ES++++ N++E
Sbjct: 516 QDLQSKFVAKENEVQSLHSKLTD-------TLVSKQQLEQRLM-QLMESEQKRVNKEESL 567
Query: 986 VKEEEEQQEEEEVRSAE 1002
+ ++ E+ E A+
Sbjct: 568 QMQVQDILEQNEALKAQ 584
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 57.0 bits (136), Expect = 9e-08
Identities = 164/827 (19%), Positives = 332/827 (40%), Gaps = 111/827 (13%)
Query: 197 TTLLTDSENRLLLFPSMKPNKRV---EVAQLNDVMDTMLERAGVENQEYTGPTKMHKLLH 253
TTL+ + + L ++K + QL M T ER+ V T+M +
Sbjct: 328 TTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVI------TRMKDRIG 381
Query: 254 ILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIA--RQMIDFYKDLV- 310
L+KE ++ H V + ++ K ++ QM +IA +Q +D V
Sbjct: 382 TLEKEHNVFQNKIH-------VSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVS 434
Query: 311 -TQRVMDQRILEEL----YNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNA 365
T ++ + EL ++ ++ ELT + ++ +V+ K E+A L L A
Sbjct: 435 NTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQ-KKNAEQAATQLKVQLQEA 493
Query: 366 EKNAKIVEEYHDLYTLQRERMENDMK-KLVAERDIWSSATYELALKVIERNRVILARRLY 424
E+ + V+ Y T + E + D++ K VA+ + S +L ++ + + + R +
Sbjct: 494 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQ-LEQRLMQ 552
Query: 425 LNEKGWNKYTKHFIILLSNKDT-EDLALLQKLTQKWRNLV------NKLKQEVEQMEEST 477
L E + K + + +D E L+ Q++ + + + L +E+ ++
Sbjct: 553 LMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEK 612
Query: 478 SETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLS 537
+ +K +D L ++ K+ + N+ + + ++ Q + NE+
Sbjct: 613 DKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQ----------- 661
Query: 538 KYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRING 597
A + +S+ + R E++ I +E++I
Sbjct: 662 ---------------AAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKIL--- 703
Query: 598 DNGYSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVP 657
N +K L S + L + N + + + QE DEK+ ++ L+ L +
Sbjct: 704 -NDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLET--GLIQVAT 760
Query: 658 QHIDVDSVSVLQAYIFNMIQQWLLKIGNEINNGNI--ELQH--HMDELHISMIQWMVNLL 713
+ +++++ + + +Q K ++++ ++ EL+ H + I ++ ++
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Query: 714 ILMIPNFTDQDCLLKLEEESAEKHDIGVARLE-LDAIELTRKLYQYSSYLSSCCKGMVTA 772
+L + N LK +E A K +IG +LE + +T K+ + + L KG
Sbjct: 821 LLKVANKEKTVQDLK-QEIKALKEEIGNVQLEKAQQLSITSKVQELQNLL----KGKEEQ 875
Query: 773 MALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEE 832
M K+ K +DL K ++ E + + + L E
Sbjct: 876 MNTMKAVLEEKE--KDLANTGKWLQDLQEENESLKAHVQEVAQHN-----------LKEA 922
Query: 833 EAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVH 892
+ +F E EI KE E E K +L+ KER + S K +L++ + +DEN
Sbjct: 923 SSASQFEELEI--VLKEKENELK---RLEAMLKERESDLSS----KTQLLQDV-QDEN-- 970
Query: 893 SKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEK 952
LF++ + +++ +Q + + E + VI ++++ + N + +DA E
Sbjct: 971 --KLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNEL----DSLKDAVE- 1023
Query: 953 LHHTLIKNKDLEELVMTSRKE-SKEEKENQDEREVKEEEEQQEEEEV 998
H KN DL E + + + EK QD+ +E QQ+ E V
Sbjct: 1024 --HQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAV 1068
Score = 53.5 bits (127), Expect = 1e-06
Identities = 167/792 (21%), Positives = 307/792 (38%), Gaps = 130/792 (16%)
Query: 278 ADRGELLSKVRE-RYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRE 336
++R L SK E + +Q ++ + + + + L ++ LE++ +V ++ R
Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684
Query: 337 LCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMEND----MKK 392
L H++ E K +LN ++N + E L TL E+ D M+K
Sbjct: 685 LEEQLQHEISNKMEEFK--------ILN-DQNKALKSEVQKLQTLVSEQPNKDVVEQMEK 735
Query: 393 LVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALL 452
+ E+D EL +E + +A + E+ N L K+ +DL
Sbjct: 736 CIQEKDEKLKTVEEL----LETGLIQVATK----EEELNAIRTENSSL--TKEVQDLKAK 785
Query: 453 QKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILS-PNKGNIFNS 511
Q + +LV +LK+ + + KDG IK E E ++L NK
Sbjct: 786 QNDQVSFASLVEELKKVIHE------------KDGKIKSVEELLEAELLKVANK----EK 829
Query: 512 VLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMP 571
+ D KQ K L E+ G+V L K L I +QE + N K E +M
Sbjct: 830 TVQDLKQEIKALKEE----IGNVQLEKAQQLSITSKVQE--------LQNLLKGKEEQMN 877
Query: 572 SERQYMEEIIKNI-------QKLYKEYE-IRINGDNGYSKILPSLISSLDFCSFKLENLE 623
+ + +EE K++ Q L +E E ++ + L S+ F E LE
Sbjct: 878 TMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQF-----EELE 932
Query: 624 FPDTPLE-EWQEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQ----- 677
E E + ++ + E +S L L V + + Q N Q
Sbjct: 933 IVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFP 992
Query: 678 --QWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEE---- 731
+ LLK+ +E L + +D L ++ L N+ + L E+
Sbjct: 993 PHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQD 1052
Query: 732 ---ESAEKHDIGVARLELDAIELTRKLY---------QYSSYLSSCCKGMVTAMALSKST 779
+++++ V +EL+A E+ +KL+ Y +L K MA + +
Sbjct: 1053 KVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGS 1112
Query: 780 NSHKNATEDLYEVDK----LKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAV 835
K L E D+ L+ EC ++ +L+ +G ++++R +E+E
Sbjct: 1113 EEVKVLEHKLKEADEMHTLLQLECEKY----KSVLAETEG------ILQKLQRSVEQEEN 1162
Query: 836 KEFIEPEIDESFKEDEE-------ESKEDRKLQEENKE-----RAEEQPSTSTEKEKLIR 883
K ++ +DES K ++ +E +L+ ENK+ R E EK ++ R
Sbjct: 1163 KWKVK--VDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMER 1220
Query: 884 FIGEDENVHSKPLF---ETDVLSSWRESAKQGT----LAQKYLEAMAVIEHMQEKLLEVE 936
E K L + + S+ E+ +Q L + E + + Q + +V
Sbjct: 1221 STYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVA 1280
Query: 937 NRARQAEEKFEDAYEKL-----HHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEE 991
+A++ E K+ T+I+N D+ +S KE+ NQ ++++ +
Sbjct: 1281 GDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQ 1340
Query: 992 QQEEEEVRSAEN 1003
++ + E+
Sbjct: 1341 AVNQQLTKEKEH 1352
Score = 37.0 bits (84), Expect = 0.094
Identities = 50/240 (20%), Positives = 106/240 (44%), Gaps = 39/240 (16%)
Query: 774 ALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEE 833
A+S +TN ++ + E++KL+++ +N + K L EE+++ E+
Sbjct: 432 AVSNTTNQLES--KQSAELNKLRQDYARLVNELT--------EKTGKLQQEEVQKKNAEQ 481
Query: 834 AVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHS 893
A + ++ ++ E+ + EE RK E++ ++ S KE E +++HS
Sbjct: 482 AATQ-LKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKEN------EVQSLHS 534
Query: 894 KPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFED----- 948
K TD L S ++ L Q+ ++ M E Q+++ + E+ Q ++ E
Sbjct: 535 KL---TDTLVSKQQ------LEQRLMQLM---ESEQKRVNKEESLQMQVQDILEQNEALK 582
Query: 949 -AYEKLHHTLIKNKDL----EELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAEN 1003
++ H + EEL ++ K+ K+ +D + + +EEE++ +N
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQN 642
Score = 35.4 bits (80), Expect = 0.27
Identities = 40/197 (20%), Positives = 85/197 (43%), Gaps = 23/197 (11%)
Query: 821 LTYEEIERL-LEEEAVKEFIEPEIDESFKED---------EEESKEDRKLQEENKERAEE 870
++Y+E +++ ++ + V+E +E EI +E+ E ++ E NK R +
Sbjct: 396 VSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDY 455
Query: 871 QPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYL-----EAMAVI 925
+ EK + E+ + T + +E+ ++ Q Y+ E A
Sbjct: 456 ARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQ 515
Query: 926 EHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDERE 985
+ +Q K + EN + K D TL+ + LE+ +M ES++++ N++E
Sbjct: 516 QDLQSKFVAKENEVQSLHSKLTD-------TLVSKQQLEQRLM-QLMESEQKRVNKEESL 567
Query: 986 VKEEEEQQEEEEVRSAE 1002
+ ++ E+ E A+
Sbjct: 568 QMQVQDILEQNEALKAQ 584
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 57.0 bits (136), Expect = 9e-08
Identities = 142/757 (18%), Positives = 299/757 (39%), Gaps = 108/757 (14%)
Query: 323 LYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQ 382
L + I+EL R + A + T++ EK+H L + + + +++ ++ Q
Sbjct: 1244 LKEHQETIDELRRSVSEKTAQIIN-TQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQ 1302
Query: 383 RERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLS 442
N+++ L + S T L IE R L LNEK
Sbjct: 1303 ETM--NELELLTEQSTTKDSTT----LARIEMER------LRLNEK-------------F 1337
Query: 443 NKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILS 502
+ E++ L K + + L+ + +Q++E ETL +++ K ++ N K+
Sbjct: 1338 QESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKE--K 1395
Query: 503 PNKGNIFNSVLLDFKQWQKILNEKKEEFTG--DVLLSKYDTLKIIKHLQENWADIGLGIF 560
N+ S + FK L + E G L +D +K + +++ + +
Sbjct: 1396 DNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQ 1455
Query: 561 NRHKSLEG---EMPSERQYMEEIIKNIQKLYKEYE-----IRINGDNGYSKILPSLISSL 612
+ L+ E+ ++ EE +K KE E +R+N ++I ++ L
Sbjct: 1456 SESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEI-STIQKQL 1514
Query: 613 DFCSFKLENL------EFPDTPLEEWQEIDEKINEMKSHLDI--------------LLNL 652
+ + KL+N + +++ E+ EK+NE+K + +L L
Sbjct: 1515 EAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLEL 1574
Query: 653 TGIVPQHIDVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNL 712
T + + + + + + +Q+ L +++ E+ M E Q+ L
Sbjct: 1575 TNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQF---L 1631
Query: 713 LILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTA 772
+ + ++ C ++ +E E + + +E + I LT+ L++ + S K
Sbjct: 1632 KMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDL 1691
Query: 773 MALSKST---------NSHKNATEDLYEVDKLK------KECYEWINTCSCLLSNIKGRK 817
++ ++ N + T DL + ++LK KE E I+ ++S K +
Sbjct: 1692 RSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSE-KTNE 1750
Query: 818 ITLLT--YEEIERLLEEEAVKEFIEPEIDESFKEDEEE----------------SKEDRK 859
I+ + E L+ + +K E I ++++E S +
Sbjct: 1751 ISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKD 1810
Query: 860 LQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYL 919
L+ N + E+ + +LI + +D N K + E + L + TL++ +
Sbjct: 1811 LENSNAKLQEKIQELKANEHQLIT-LKKDVNETQKKVSEMEQLKKQIKDQSL-TLSKLEI 1868
Query: 920 EAMAVIEHMQEKLLEVEN------RARQAEEKF----EDAYEKLHHTLIKNKDLEELVMT 969
E + + + + E L E+++ R+ EE + E L T ++ ++++ + T
Sbjct: 1869 ENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKT 1928
Query: 970 SRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSK 1006
+R SKE KE D+ K E+ + +++ + SK
Sbjct: 1929 ARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSK 1965
Score = 55.8 bits (133), Expect = 2e-07
Identities = 163/767 (21%), Positives = 316/767 (41%), Gaps = 101/767 (13%)
Query: 272 QVSVDCADRGELLSKV--RERYVQ-MLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKH 328
++ + +++ +L S+V +E VQ +L++I + D + DQ E NFK
Sbjct: 769 ELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQ----EFQNFKT 824
Query: 329 VIEELTRELCLVRAHDVKLTKE----TEKAHK-DLAQALLNAEKNAKIVEEYHDLYTLQR 383
+ + ++ +V + ++ +E +++A K D + L E + K E +Q
Sbjct: 825 LHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQ- 883
Query: 384 ERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSN 443
ER+ N+M++L + + S L+ +ER + ++ +L + T+
Sbjct: 884 ERL-NEMEQLKEQLENRDST-----LQTVEREKTLITEKLQQTLEEVKTLTQ-------- 929
Query: 444 KDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFN------E 497
+ +DL LQ+ Q R+ + + M T E L+ + L + QE N
Sbjct: 930 -EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKIS 988
Query: 498 KDI-----LSPNKGNI---FNSVLLDFKQWQKILNEKKEEFTGDVLLSKY--DTLKIIKH 547
+++ + N G F ++ + Q + + + T DV ++ KI
Sbjct: 989 EEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSL 1048
Query: 548 LQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQK-LYKEYEIRINGDNGYSKILP 606
+QE + LE + + Q ++ +NI+ + + E+R+ GD K
Sbjct: 1049 IQEK--------NELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDE--LKKQQ 1098
Query: 607 SLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDI----LLNLTGIVPQHIDV 662
+++ + K E E T + E++EK+ E L LLN+
Sbjct: 1099 EIVAQEKNHAIKKEG-ELSRT-CDRLAEVEEKLKEKSQQLQEKQQQLLNVQ--------- 1147
Query: 663 DSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTD 722
+ +S +Q I N I+ + NE+ N + L+H M+ + + Q +N + + T
Sbjct: 1148 EEMSEMQKKI-NEIEN----LKNELKNKELTLEH-METERLELAQ-KLNENYEEVKSITK 1200
Query: 723 QDCLLKLEEESAEK---HDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKST 779
+ +LK ++S E H G R E++A L K +++ + T L +S
Sbjct: 1201 ERKVLKELQKSFETERDHLRGYIR-EIEATGLQTKEELKIAHIH-LKEHQETIDELRRSV 1258
Query: 780 NSHKNA----TEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAV 835
S K A T+DL + +E ++ LL N+K T T E+E L E+
Sbjct: 1259 -SEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTT 1317
Query: 836 KEF-----IEPE---IDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGE 887
K+ IE E ++E F+E +EE K K ++ K E + + ++L I E
Sbjct: 1318 KDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKE---ALEVKHDQLKEHIRE 1374
Query: 888 DENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFE 947
+ + + + +E + T K + M + LL +E ++ +
Sbjct: 1375 TLAKIQESQSKQEQSLNMKEKDNETT---KIVSEMEQFKPKDSALLRIEIEMLGLSKRLQ 1431
Query: 948 DAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQE 994
++++++ + DL+ L + ES + KEN E K E ++E
Sbjct: 1432 ESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEE 1478
Score = 50.8 bits (120), Expect = 6e-06
Identities = 156/761 (20%), Positives = 307/761 (40%), Gaps = 117/761 (15%)
Query: 325 NFKHVIEELTRELCLVRAHD--VKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQ 382
N +V E T E L R + L K+ E+ + + ++ A+++EE L +Q
Sbjct: 331 NTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQ 390
Query: 383 RERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLS 442
E++EN + LV SS T + LK + RV +N+ + Y F I +
Sbjct: 391 NEKIENLTRMLVTS----SSLTLQQELKAKRKRRVTWCLG-KINKMKNSNYADQFNIPTN 445
Query: 443 NKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGL--IKWQ---EFFNE 497
+T K L L +E+++ S S+ D L I+W + N+
Sbjct: 446 ------------ITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQ 493
Query: 498 KDILSP--NKGNIFNSVLLDFKQ-------WQKILNEKK--EEFTGDVLLSKYDTLKIIK 546
++I S + +++++LD++Q + L EK +EF +K D +
Sbjct: 494 ENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLI 553
Query: 547 HLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIR----INGDNGYS 602
H N ++ ++ LE E+ S+ + + E I+KL + + + I D YS
Sbjct: 554 HEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYS 613
Query: 603 ----------------KILPSLISSLDFCSFKLENLEFPDTPLE---EWQEIDEKINEMK 643
+L + + + ENLE + E +++++ I +
Sbjct: 614 LESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQ 673
Query: 644 SHLDILLNLTGIVPQHID--VDSVSVLQAYIFNMIQQWL---LKIGNEINNGNIELQHHM 698
S L+ + + + + + ++ L + I + + L L++ +I + EL +
Sbjct: 674 SQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEV 733
Query: 699 DELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQY 758
+E + ++ + +P+ ++ +++++S E H I + +L + E+ K +
Sbjct: 734 EENEALREEVILLSELKSLPSEVER-LRKEIQDKSEELHIITSEKDKLFS-EVVHKESRV 791
Query: 759 SSYLSSCCK---GMVTAMALSKSTNSHKNATEDLY-------------------EVDKLK 796
L K + T + KST+ + L+ E+ L
Sbjct: 792 QGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLS 851
Query: 797 KECYEWINTCSCLLSNI--KGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEES 854
KE ++ ++ L + + K +++ T E ERL E E +KE +E D + + E E
Sbjct: 852 KEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENR-DSTLQTVEREK 910
Query: 855 -----------KEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLS 903
+E + L +E + + Q S E+++L I + N++ + + L
Sbjct: 911 TLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMN---IDTQEQLR 967
Query: 904 SWRESAKQ-----GTLAQKYLEAMAVIEHMQEKLLEVENRARQ---AEEKFEDAYEKLHH 955
+ ES KQ TL K E ++ HM+E E ++ +Q +K +D K
Sbjct: 968 NALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQ 1027
Query: 956 TLIKNKDLEELVMTSRK-----ESKEEKENQDEREVKEEEE 991
TL + E++ RK + K E + E + E+E+
Sbjct: 1028 TLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQ 1068
Score = 45.1 bits (105), Expect = 3e-04
Identities = 155/816 (18%), Positives = 311/816 (38%), Gaps = 84/816 (10%)
Query: 217 KRVEVAQLNDVMDTMLERAGVENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVD 276
K E+ L + +T ++ +EN E T ++ ++LH +E +L
Sbjct: 1642 KMCEIEHLKEQFET--QKLNLENIE-TENIRLTQILHENLEEMRSVTKERDDLRSVEETL 1698
Query: 277 CADRGELLSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQR---ILEELYNFKHVIEEL 333
+R +L +RE + L++ I Q +D+ + E+ ++ ++L
Sbjct: 1699 KVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDL 1758
Query: 334 TRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKL 393
++A D+K+ +E AH L + +K IV E D + ++ +EN KL
Sbjct: 1759 EHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKL 1818
Query: 394 VAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQ 453
+ + ++L + + V ++ + K K + LS + E+L L Q
Sbjct: 1819 QEKIQELKANEHQL---ITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQ 1875
Query: 454 KLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVL 513
KL + + + +K+ ETLK+ +D L + + +D+
Sbjct: 1876 KLHENLEEMKSVMKE--RDNLRRVEETLKLERDQLKESLQETKARDL------------- 1920
Query: 514 LDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSE 573
E ++E +LSK + + + L+E ++ + I + K L+
Sbjct: 1921 -----------EIQQELKTARMLSK-EHKETVDKLREKISEKTIQISDIQKDLD------ 1962
Query: 574 RQYMEEIIKNIQKLYKE--YEIRINGDNGYSKILPSLISSLDFCSFKLENLEFPDTPLEE 631
+ +E+ K IQ+L K+ +R+ D S + + L F+ +NL ++
Sbjct: 1963 -KSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLK-KQFEAQNLSMQSVRMDN 2020
Query: 632 WQ------EIDEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQQWLLKIGN 685
+Q E E+I + D L + + D ++ L+ I Q +K
Sbjct: 2021 FQLTKKLHESLEEIRIVAKERDELRRIKESLKMERD-QFIATLREMIARDRQNHQVKPEK 2079
Query: 686 EINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCL----LKLEEESAEKHDIGV 741
+ + Q H+ E + LL +CL L LE+E + ++ +
Sbjct: 2080 RLLSDG---QQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSM 2136
Query: 742 ---ARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKE 798
A L L ++ T+ + + + C M K S+ V K+K+E
Sbjct: 2137 RVKANLSLPYLQ-TKHIEKLFTANQRCSMEFHRIMKKLKYVLSY---------VTKIKEE 2186
Query: 799 CYEWINTCSC-LLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKED 857
+E IN + ++ +K L+ + +++ + + +E + +++++ EE +D
Sbjct: 2187 QHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPS-RELRDLKLNQNMDLHIEEILKD 2245
Query: 858 RKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQK 917
E + E Q S KE + +F+ E N F+ + L + +
Sbjct: 2246 FSESEFPSIKTEFQQVLSNRKE-MTQFLEEWLNTR----FDIEKLKNGIQKENDRICQVN 2300
Query: 918 YLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKL---HHTLIKNKDLEELVMTSRKES 974
+I M E E E R+ +++E + L + L KN + + S +
Sbjct: 2301 NFFNNRIIAIMNES-TEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQV 2359
Query: 975 KEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
++ V Q E++R ENS K+
Sbjct: 2360 NPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKE 2395
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 57.0 bits (136), Expect = 9e-08
Identities = 162/806 (20%), Positives = 324/806 (40%), Gaps = 131/806 (16%)
Query: 217 KRVEVAQLNDVMDTMLE-----RAGVENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIR 271
K E+AQL + M R E E ++ K L +K + + E+
Sbjct: 380 KEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDE 439
Query: 272 QVSV-------DCADRGELLSKVRERYVQMLDQIARQMIDFYKDLVTQRVM--DQRILEE 322
Q+ + + LS+V++ V ++ + + + I + L + + +Q + ++
Sbjct: 440 QIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKK 499
Query: 323 LYNFKHVIEELTR-ELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTL 381
L + +E + L ++ +K+++E E+ + LA L +K A + E + L L
Sbjct: 500 LQTREREFQEQMKVALEKSQSEYLKISQEKEQ-QESLALEELELQKKAILTESENKLRDL 558
Query: 382 QRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILL 441
Q+E + L E + E +L+ + LA L E NK+ K +++
Sbjct: 559 QQEAETYRTRILELESSL------EKSLQENKNQSKDLAVHL---EAEKNKHNKEITVMV 609
Query: 442 SNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDIL 501
TE +L + W + LKQ+ + E E + K+ L+K +E + I
Sbjct: 610 EKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIE 669
Query: 502 SPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFN 561
N+ + LD KQ + L E + + LK L+E + +
Sbjct: 670 EMNEKTLEK---LDVKQTE--LESLSSELS--------EVLKARHKLEEELSVLKDQTDK 716
Query: 562 RHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKLEN 621
+ LE +M ++ + ++ + + KE+E+ I K L I+ L+
Sbjct: 717 MKQELEAKMDEQKNHHQQ---QVDSIIKEHEVSIQRT---EKALKDQINQLELL------ 764
Query: 622 LEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQQWLL 681
+E D+ + E ++H++ NL + + + + +F Q
Sbjct: 765 ----------LKERDKHLKEHQAHVE---NLEADIKRSEGELQQASAKLDVFQSYQSATH 811
Query: 682 KIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLK-LEEESAEKHDIG 740
+ +LQ + +L T++ L K + E A+K D+
Sbjct: 812 EQTKAYEEQLAQLQQKLLDLE------------------TERILLTKQVAEVEAQKKDVC 853
Query: 741 VARLELDA-----IELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKL 795
ELDA +L ++L + +S + K + T + SK + +K E ++
Sbjct: 854 T---ELDAHKIQVQDLMQQLEKQNSEMEQKVKSL-TQVYESKLEDGNK-------EQEQT 902
Query: 796 KKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESK 855
K+ E N +L +G+K +EIE L ++ + KE ++E + E + K
Sbjct: 903 KQILVEKEN---MILQMREGQK------KEIEILTQKLSAKEDSIHILNEEY---ETKFK 950
Query: 856 EDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLA 915
K E+ K++A+E T K+KL+ D+ K E L L+
Sbjct: 951 NQEKKMEKVKQKAKEMQETL--KKKLL-----DQEAKLKKELENTALE----------LS 993
Query: 916 QKYLEAMA-VIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELV-MTSRKE 973
QK + A ++E Q + + + E ++ E L T + ++L +++ + +K
Sbjct: 994 QKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESL--TEVHRRELNDVISIWEKKL 1051
Query: 974 SKEEKENQDEREVKEEEEQQEEEEVR 999
+++ +E Q+ E++ +E++QE E++
Sbjct: 1052 NQQAEELQEIHEIQLQEKEQEVAELK 1077
Score = 53.9 bits (128), Expect = 7e-07
Identities = 161/841 (19%), Positives = 349/841 (41%), Gaps = 124/841 (14%)
Query: 269 LIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFK- 327
L +QV+ A + ++ +++ +Q+ D + Q ++ + Q+V + L ++Y K
Sbjct: 838 LTKQVAEVEAQKKDVCTELDAHKIQVQDLM--QQLEKQNSEMEQKV---KSLTQVYESKL 892
Query: 328 ---HVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIV--EEYHDLYTLQ 382
+ +E T+++ + + + + +E +K ++ L+A++++ + EEY + Q
Sbjct: 893 EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQ 952
Query: 383 RERMENDM-----------KKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWN 431
++ME KKL+ + AL++ ++ + A+ L + +
Sbjct: 953 EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQAN-- 1010
Query: 432 KYTKHFIILLSNKDTEDLALLQKLTQKWRNLVN--------KLKQEVEQMEESTSETLKI 483
+ +S +T ++ LT+ R +N KL Q+ E+++E L+
Sbjct: 1011 --SAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQE 1068
Query: 484 VKDGLIKWQE----FFNEKDILSPN----------KGNIFNSVLLDFKQWQKILNEKKEE 529
+ + + ++ F EK+ ++ + N + KQ +N ++
Sbjct: 1069 KEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQD 1128
Query: 530 FTG--------DVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEII 581
T +V L+K +LK LQE ++ + + K E+ S+ + +E
Sbjct: 1129 ETKLKAHLEKLEVDLNK--SLKENTFLQEQLVELKM-LAEEDKRKVSELTSKLKTTDEEF 1185
Query: 582 KNIQKLYKEYEIRINGDN-GYSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKIN 640
++++ +++ + + + K+ L LD C K E L T +E IN
Sbjct: 1186 QSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKT--------NELIN 1237
Query: 641 EMKSHLDILLN-LTGIVPQHIDVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQ---H 696
S + +L+ ++ + V +++ + ++ L ++ E N NI Q H
Sbjct: 1238 ISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATH 1297
Query: 697 HMDELHISMIQWMVNLLILMIPNFTDQ--------------DCLLKLEEESAE------- 735
++E + ++ L+ Q C+ +L++E +E
Sbjct: 1298 QLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTL 1357
Query: 736 -KHDIGVARLELDAI--ELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHK----NATED 788
K ++ ++E+ ++ +LT Q + +S K + +L K + K + +D
Sbjct: 1358 MKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAIS-SLRKQYDEEKCELLDQVQD 1416
Query: 789 L-YEVDKLKKE---CYEWINTCSCLLSNIKGRKITLLTY-----EEIERLLEEEAVKEFI 839
L ++VD L KE E ++ S S K + + T +E++ LE ++ + +
Sbjct: 1417 LSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYE 1476
Query: 840 EPEIDESFKE--DEEESKED--RKLQEENKERAEEQPST-STE-KEKLIRFIGEDENVHS 893
+ E KE D++ + D + E++K + E++ S TE K + R + ++++
Sbjct: 1477 KDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQ 1536
Query: 894 KPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKF----EDA 949
K + + + +Q + K E + ++H QE E +NR ++AEEK
Sbjct: 1537 KTIEIESLNEVLKNYNQQKDIEHK--ELVQKLQHFQELGEEKDNRVKEAEEKILTLENQV 1594
Query: 950 YEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPK 1009
Y K K+LE + ++ + SKEE+ E ++ E + E R AE + K
Sbjct: 1595 YSMKAELETKKKELEHVNLSVK--SKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK 1652
Query: 1010 K 1010
K
Sbjct: 1653 K 1653
Score = 46.2 bits (108), Expect = 2e-04
Identities = 159/816 (19%), Positives = 327/816 (40%), Gaps = 125/816 (15%)
Query: 213 MKPNKRVEVAQLNDVMDTMLERAGVENQEYTGPTK------MHKLLHILKKEQTIYNMIF 266
MK + ++A+L + + L R + QE T + ++ L+K Q+ Y I
Sbjct: 470 MKKSSEEQIAKLQKLHEKELAR---KEQELTKKLQTREREFQEQMKVALEKSQSEYLKIS 526
Query: 267 HELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFYKDLVTQRV----MDQRILEE 322
E +Q S+ L ++ + +L + ++ D ++ T R ++ + +
Sbjct: 527 QEKEQQESL-------ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 579
Query: 323 LYNFKHVIEELTRELCLVR-AHDVKLTKETEKAHKDLA-----QALLNAEKNAKIVEEYH 376
L K+ ++L L + H+ ++T EK +L Q L EK + ++Y
Sbjct: 580 LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ 639
Query: 377 DLYTLQRERMENDMKKLVAERDI-WSSATYELALKVIERNRV------ILARRLYLNEKG 429
RE+ E + + L+ +++I + + E+ K +E+ V L+ L K
Sbjct: 640 TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKA 699
Query: 430 WNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLI 489
+K + +L D L K+ ++ + ++ +++ E S T K +KD +
Sbjct: 700 RHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQI- 758
Query: 490 KWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKK---EEFTGDVLLSKYDTLKIIK 546
N + L K+ K L E + E D+ S+ +
Sbjct: 759 --------------------NQLELLLKERDKHLKEHQAHVENLEADIKRSEGE------ 792
Query: 547 HLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKI-- 604
LQ+ A L +F ++S E + Y E++ + QKL RI +++
Sbjct: 793 -LQQ--ASAKLDVFQSYQSATHE--QTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEA 847
Query: 605 -LPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNL--TGIVPQHID 661
+ + LD ++++L Q+++++ +EM+ + L + + + + +
Sbjct: 848 QKKDVCTELDAHKIQVQDL---------MQQLEKQNSEMEQKVKSLTQVYESKLEDGNKE 898
Query: 662 VDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFT 721
+ + NMI Q EI +L D +HI ++ F
Sbjct: 899 QEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET--------KFK 950
Query: 722 DQDCLLKLEEESAEKHDIGVAR------------LELDAIELTRKLYQYSSYLSSCCKGM 769
+Q+ ++ ++ A++ + + LE A+EL++K Q+++ + +
Sbjct: 951 NQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQAN 1010
Query: 770 VTAM--ALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIE 827
+ A+S+ + K E L EV + E + S + + L EI+
Sbjct: 1011 SAGISDAVSRLETNQKEQIESLTEVHR-----RELNDVISIWEKKLNQQAEELQEIHEIQ 1065
Query: 828 RLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKER---AEEQPSTSTEKEKLIRF 884
+E+ V E ++ +I E EE +KE L+EE ++ E +K +
Sbjct: 1066 LQEKEQEVAE-LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNS 1124
Query: 885 IGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYL-EAMAVIEHMQEKLLEVENRARQAE 943
+ +DE L + +V +S K+ T Q+ L E + E + K+ E+ ++ + +
Sbjct: 1125 LAQDETKLKAHLEKLEV--DLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1182
Query: 944 EKFE---DAYEKLHHTLIKNKDLEELVMTSRKESKE 976
E+F+ ++EK NK LE+ + +K S+E
Sbjct: 1183 EEFQSLKSSHEK------SNKSLEDKSLEFKKLSEE 1212
Score = 44.7 bits (104), Expect = 5e-04
Identities = 151/837 (18%), Positives = 326/837 (38%), Gaps = 126/837 (15%)
Query: 247 KMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFY 306
+M+K + LK+E + +EL Q+ A ++ + + ++ + + +D
Sbjct: 1089 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAH----VNSLAQDETKLKAHLEKLEVDLN 1144
Query: 307 KDLVTQRVMDQRILEELY---NFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALL 363
K L + ++++E K + ELT +L L EK++K L L
Sbjct: 1145 KSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSL 1204
Query: 364 NAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRL 423
+K ++ + D+ + E + + T EL + IL+R
Sbjct: 1205 EFKKLSEELAIQLDICCKKTEAL-------------LEAKTNELINISSSKTNAILSRIS 1251
Query: 424 YLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLKI 483
+ + K +++ + +E A L++LT++ L +Q Q+EE ++ +K
Sbjct: 1252 HCQHR--TTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQ-IKS 1308
Query: 484 VKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKEEFTGDV-----LLSK 538
+K + + EK+ L GN + + + + + K+E + ++ + +
Sbjct: 1309 MKADI---ESLVTEKEALQKEGGNQQQAA----SEKESCITQLKKELSENINAVTLMKEE 1361
Query: 539 YDTLKI-IKHLQENWADIGLGIFNRHKSLEGEMPSE---RQYMEE---IIKNIQKLYKEY 591
K+ I L + D+ + + N E E +QY EE ++ +Q L +
Sbjct: 1362 LKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKV 1421
Query: 592 EI----RING-------DNGYSKILPSLISSLDFCSFKLENLEFP-DTPLEEWQEIDEKI 639
+ +I+ N +S+ S ++ L+ + +E E DE+I
Sbjct: 1422 DTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQI 1481
Query: 640 NEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMD 699
N +K LD + ++ D + +++ + E+ + + D
Sbjct: 1482 NLLKEELDQQNKRFDCLKGEMEDDK---------SKMEKKESNLETELKSQTARIMELED 1532
Query: 700 ELHISMIQWMVNLLILMIPNFTDQ------DCLLKLE--EESAEKHDIGVARLELDAIEL 751
HI+ + L ++ N+ Q + + KL+ +E E+ D V E + L
Sbjct: 1533 --HITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1590
Query: 752 TRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVD------KLKKECYEWI-- 803
++Y + L + K + KS A ED E + +LK++ + I
Sbjct: 1591 ENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAA 1650
Query: 804 ---------------------NTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPE 842
+ S L + ++ R+ + EE + +E + I P
Sbjct: 1651 IKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPR 1710
Query: 843 IDESFKEDEEESKEDRK--LQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETD 900
++ E+ + D + +Q+ +E+ TEKEKL++ +G+++ FE
Sbjct: 1711 SAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE-- 1768
Query: 901 VLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKN 960
+ +Y E + +EH + K E ++ +E+ E+ +K ++LI
Sbjct: 1769 -------------MRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKK--YSLIVA 1813
Query: 961 KDLEELVMTSRKESKEEKEN--QDEREVKEEEE---QQEEEEVRSAENSSKSPKKGH 1012
+ +E+ + ++K+ EN D ++ +E+E Q E++++ ++ K+ H
Sbjct: 1814 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVH 1870
Score = 40.4 bits (93), Expect = 0.008
Identities = 43/199 (21%), Positives = 89/199 (44%), Gaps = 18/199 (9%)
Query: 823 YEEIERLL----EEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEK 878
+EE+E+ L + E + ++ E+DE K E+ S+E+R ++ R +++ +K
Sbjct: 413 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK 472
Query: 879 EKLIRFIGEDENVHSKPLFETDVLSSWRESAKQ-GTLAQKYLEAMAV-IEHMQEKLLEVE 936
E++ + L E ++ +E K+ T +++ E M V +E Q + L++
Sbjct: 473 S------SEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKIS 526
Query: 937 NRARQAEEKFEDAYEKLHHTLI-----KNKDLEELVMTSRKESKEEKENQDEREVKEEEE 991
Q E + E ++ K +DL++ T R E E+ E+ ++E +
Sbjct: 527 QEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRIL-ELESSLEKSLQENKN 585
Query: 992 QQEEEEVRSAENSSKSPKK 1010
Q ++ V +K K+
Sbjct: 586 QSKDLAVHLEAEKNKHNKE 604
Score = 37.7 bits (86), Expect = 0.055
Identities = 54/238 (22%), Positives = 97/238 (40%), Gaps = 29/238 (12%)
Query: 792 VDKLKKECYEWINTCSCLLSNIKGRKITLLT---------YEEIERLLEEEAVKEFI--- 839
VD +KK E I L RK LT ++E ++ E++ E++
Sbjct: 467 VDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKIS 526
Query: 840 -EPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFE 898
E E ES +E E ++ L E + + Q T + +++ E + +
Sbjct: 527 QEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 586
Query: 899 TDVLSSWRESAKQG------TLAQKYLEAMAVIEHMQEKL----LEVENRARQAE-EKFE 947
+ L+ E+ K + +K+ + ++H Q+ L L+V + Q E EK
Sbjct: 587 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLR 646
Query: 948 DAYEKLHHTLIKNKDLEELVMTSRKESKEEK--ENQDEREVKEEEEQQEEEEVRSAEN 1003
+ E+ TL+K+K E++ + E EK E D ++ + E E EV A +
Sbjct: 647 EKCEQEKETLLKDK---EIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARH 701
Score = 37.4 bits (85), Expect = 0.072
Identities = 38/186 (20%), Positives = 83/186 (44%), Gaps = 3/186 (1%)
Query: 819 TLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEK 878
T+ E ER+ ++ + + +D K EE+ + +KL E+ R +EQ T +
Sbjct: 443 TIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR-KEQELTKKLQ 501
Query: 879 EKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENR 938
+ F + + K E +S +E + L + L+ A++ + KL +++
Sbjct: 502 TREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQE 561
Query: 939 ARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEV 998
A + + L +L +NK+ + + E+++ K N+ E V E+ + E E +
Sbjct: 562 AETYRTRILELESSLEKSLQENKN-QSKDLAVHLEAEKNKHNK-EITVMVEKHKTELESL 619
Query: 999 RSAENS 1004
+ +++
Sbjct: 620 KHQQDA 625
Score = 35.0 bits (79), Expect = 0.36
Identities = 64/284 (22%), Positives = 124/284 (43%), Gaps = 42/284 (14%)
Query: 217 KRVEVAQLN-DVMDTMLERAGVENQEYTGP---------TKMHKLLHILKKEQTIYNMIF 266
+++ V Q N + +L+R G E +E ++ KL H K+ +MI
Sbjct: 1736 EKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIG 1795
Query: 267 HELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFYKDLVTQRVMD--QRILEELY 324
H + + ++ + S + ++V+ + + I ++L + V D Q+ L+E
Sbjct: 1796 H-----LQEELEEKNKKYSLIVAQHVEK--EGGKNNIQAKQNL--ENVFDDVQKTLQEKE 1846
Query: 325 NFKHVIEELTREL--CLVR---AHDVKLTKETEKAHKDLA-QALLNAEKNAKIVEEYHDL 378
++E+ +EL CLVR H V++ + T K K A Q + K +++EE
Sbjct: 1847 LTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEEN--- 1903
Query: 379 YTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFI 438
T ++ + KL++ + + E L ER + L + + +K +
Sbjct: 1904 -TEEKSKSHLVQPKLLSNMEAQHN-DLEFKLAGAEREKQKLGKEIVRLQKD--------L 1953
Query: 439 ILLSNKDTEDLALLQKLTQKWRNLVNKLKQEVEQMEESTSETLK 482
+L + ++L +L+K + R K+KQE E +E + TLK
Sbjct: 1954 RMLRKEHQQELEILKKEYDQERE--EKIKQEQEDLELKHNSTLK 1995
Score = 34.3 bits (77), Expect = 0.61
Identities = 97/519 (18%), Positives = 201/519 (38%), Gaps = 84/519 (16%)
Query: 187 SGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMDTMLERAGVENQEYT--- 243
S +E + T L R++ K +E+ LN+V+ ++ +E++E
Sbjct: 1507 SKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKL 1566
Query: 244 ------GPTKMHKLLHILKKEQTIYNMIF---------HELIRQVSVDCADRGELLSKVR 288
G K +++ +K T+ N ++ + + V++ + E L +
Sbjct: 1567 QHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALE 1626
Query: 289 ER--------YVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLV 340
+R ++ + +++ K L++Q M+++ + + + EL +L
Sbjct: 1627 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQ--MEEKEEQYKKGTESHLSELNTKL-QE 1683
Query: 341 RAHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIW 400
R +V + +E K+ + L ++AK V Y E+ E D + V +
Sbjct: 1684 REREVHILEEKLKSVESSQSETLIVPRSAKNVAAY-------TEQEEADSQGCVQK---- 1732
Query: 401 SSATYELALKVIERNRVILARRLYLNEKGWNK---YTKHFIILLSNKDTEDLALLQKLTQ 457
TYE + V++RN + + L G K + HF + + E L L+
Sbjct: 1733 ---TYEEKISVLQRN--LTEKEKLLQRVGQEKEETVSSHFEMRCQYQ--ERLIKLEHAEA 1785
Query: 458 KWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFK 517
K + + E++EE + IV + K E N N+F+ V +
Sbjct: 1786 KQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK--EGGKNNIQAKQNLENVFDDVQKTLQ 1843
Query: 518 QWQ---KILNEKKEEFTG-------------DVLLSKYDTLKIIKHLQENWADIGLGIFN 561
+ + +IL +K +E + L SKY+ L+ ++ + N
Sbjct: 1844 EKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR---------N 1894
Query: 562 RHKSLEGEMPSERQ----YMEEIIKNIQKLYKEYEIRINGDNGYSKILPSLISSL--DFC 615
+ L E E+ +++ N++ + + E ++ G + L I L D
Sbjct: 1895 KPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLR 1954
Query: 616 SFKLENLEFPDTPLEEW-QEIDEKINEMKSHLDILLNLT 653
+ E+ + + +E+ QE +EKI + + L++ N T
Sbjct: 1955 MLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNST 1993
Score = 32.7 bits (73), Expect = 1.8
Identities = 39/184 (21%), Positives = 83/184 (45%), Gaps = 18/184 (9%)
Query: 839 IEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEK-EKLIRFIGEDENVHSKPLF 897
+EP+ + KE+ ES + +++ + E ++ E L++ E H +
Sbjct: 251 LEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKE--- 307
Query: 898 ETDVLSSWRESAKQGTLAQKYLEAMAVIE-HMQEK------LLEVENRARQAEEK----F 946
+ +L+S +E A Q L ++ E + + HM EK L + +N Q E+
Sbjct: 308 QCTLLTSEKE-ALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVI 366
Query: 947 EDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSK 1006
+ ++H TL + EE+ + + + ++ RE KE+ E+ EE+ A ++++
Sbjct: 367 AETKRQMHETLEMKE--EEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ 424
Query: 1007 SPKK 1010
++
Sbjct: 425 KTEE 428
Score = 30.8 bits (68), Expect = 6.7
Identities = 42/186 (22%), Positives = 85/186 (45%), Gaps = 14/186 (7%)
Query: 814 KGRKITLLTYEEIERLLEEEAVKEFIEPEID-ESFKEDEEESKEDRKLQEENKERAEEQP 872
K +K +L+ + +E+ E K I+ + + E+ +D +++ ++++L + E+ ++
Sbjct: 1804 KNKKYSLIVAQHVEK----EGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKEL 1859
Query: 873 STSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKL 932
+ ++K + + E E + SK + L K L ++ E + +Q KL
Sbjct: 1860 DSCLVRQKEVHRV-EMEELTSK-YEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL 1917
Query: 933 LE-VENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEE 991
L +E + E K A + K K +E+V + KE+Q E E+ ++E
Sbjct: 1918 LSNMEAQHNDLEFKLAGAERE------KQKLGKEIVRLQKDLRMLRKEHQQELEILKKEY 1971
Query: 992 QQEEEE 997
QE EE
Sbjct: 1972 DQEREE 1977
Score = 30.8 bits (68), Expect = 6.7
Identities = 45/192 (23%), Positives = 88/192 (45%), Gaps = 33/192 (17%)
Query: 811 SNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEE 870
+NI+ ++ ++++++ L+E KE +++ KE D L + + E
Sbjct: 1823 NNIQAKQNLENVFDDVQKTLQE---KELTCQILEQKIKE------LDSCLVRQKEVHRVE 1873
Query: 871 QPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQE 930
+++ EKL + + +KP T++L E + L Q L + +M+
Sbjct: 1874 MEELTSKYEKLQAL--QQMDGRNKP---TELLEENTEEKSKSHLVQPKL-----LSNMEA 1923
Query: 931 KLLEVENRARQAEEKFEDAYEKLHHTLIK-NKDLEELVMTSRKESKEE-----KENQDER 984
+ ++E + AE + +KL +++ KDL L RKE ++E KE ER
Sbjct: 1924 QHNDLEFKLAGAERE----KQKLGKEIVRLQKDLRML----RKEHQQELEILKKEYDQER 1975
Query: 985 EVKEEEEQQEEE 996
E K ++EQ++ E
Sbjct: 1976 EEKIKQEQEDLE 1987
>gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo
sapiens]
Length = 1638
Score = 57.0 bits (136), Expect = 9e-08
Identities = 71/292 (24%), Positives = 127/292 (43%), Gaps = 52/292 (17%)
Query: 733 SAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEV 792
+ E ++ + RLE + +EL+RKL + + + + V + KN E E+
Sbjct: 440 ATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKE---EI 496
Query: 793 DKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEE 852
+KL+K+ E +E+ LEE + E+D++F++ +
Sbjct: 497 EKLRKQVTE---------------------SSHLEQQLEEANA---VRQELDDAFRQIKA 532
Query: 853 ESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQG 912
K+ + LQ+E ++ + + T E L +D + + + L + E KQ
Sbjct: 533 YEKQIKTLQQEREDLNKLEVHT----EALAAEASKDRKLREQSEHYSKQLENELEGLKQK 588
Query: 913 TLAQKYLEAMAVIEHMQE--KL-LEVENRARQAEEKFEDAYEKLHHTLIKN--KDL---- 963
++ Y + IEH QE KL ++E ++ EE+ E +H IKN K+L
Sbjct: 589 QIS--YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKR-EGIHANEIKNLKKELHDSE 645
Query: 964 -------EELVMTSRKESKEEKENQDEREVKEEE--EQQEEEEVRSAENSSK 1006
+E+++ K K +E+Q ERE E E +Q E E+V E + K
Sbjct: 646 GQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKK 697
>gi|157785668 coiled-coil domain containing 39 [Homo sapiens]
Length = 941
Score = 57.0 bits (136), Expect = 9e-08
Identities = 157/790 (19%), Positives = 319/790 (40%), Gaps = 129/790 (16%)
Query: 284 LSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEEL--TRELCLVR 341
LSK+++ + D++ R ++RI +FK+V +EL T+ LC R
Sbjct: 31 LSKLKDERASLQDEL--------------REYEERINSMTSHFKNVKQELSITQSLCKAR 76
Query: 342 AHDVKLTKETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWS 401
+ E+E+ K +AQ L K+ + +R+EN+M ++ ++
Sbjct: 77 ERET----ESEEHFKAIAQRELGRVKD-------------EIQRLENEMASILEKKSDKE 119
Query: 402 SATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRN 461
+ ++ K+ + +N W++ + S D LQK Q+ N
Sbjct: 120 NGIFKATQKLD-------GLKCQMN---WDQQALEAWLEESAHKDSDALTLQKYAQQDDN 169
Query: 462 LVNKLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQK 521
+ L ++E++ ++ KI+ + L + E D + + I N KQW+
Sbjct: 170 KIRALTLQLERLTLECNQKRKILDNELTETISAQLELDKAAQDFRKIHNERQELIKQWEN 229
Query: 522 ILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEII 581
+ E+ ++ GD+ L++ + QE L + + K LE E+ + ++ + I
Sbjct: 230 TI-EQMQKRDGDI---DNCALELARIKQETREKENL-VKEKIKFLESEIGNNTEFEKRIS 284
Query: 582 KNIQKL------YKEYE---IRINGDNGYSKILPSLISSLDFCSFKLENL---------- 622
+KL Y+++E I++ G+ L SL ++++ S LE L
Sbjct: 285 VADRKLLKCRTAYQDHETSRIQLKGE------LDSLKATVNRTSSDLEALRKNISKIKKD 338
Query: 623 ---------------EFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVSV 667
E T L+E E + E ++L+ +L + +DV +++
Sbjct: 339 IHEETARLQKTKNHNEIIQTKLKEITEKTMSVEEKATNLEDMLKEEEKDVKEVDV-QLNL 397
Query: 668 LQAYIFNMIQQWLLK------IGNEINNGNIELQHHMDELHISMIQWMVNLLILMIPNFT 721
++ +F Q+ + + +EI L+H +L + + I+ +F
Sbjct: 398 IKGVLFKKAQELQTETMKEKAVLSEIEGTRSSLKHLNHQLQKLDFETLKQQEIMYSQDFH 457
Query: 722 DQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSS---YLSSCCKGMVTAMALSKS 778
Q ++ E + LE +EL + L + S L + K + + K
Sbjct: 458 IQQVERRMSRLKGEINSEEKQALEAKIVELRKSLEEKKSTCGLLETQIKKLHNDLYFIKK 517
Query: 779 TNSHKNATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEF 838
+S KN+ E + K+ E +I+ L KG K L+ + + + LE + +E
Sbjct: 518 AHS-KNSDEKQSLMTKI-NELNLFIDRSEKELDKAKGFKQDLMIEDNLLK-LEVKRTREM 574
Query: 839 IEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGED-ENVHS---- 893
+ + +E + K ++L +ER EE T IR++ ++ EN+ +
Sbjct: 575 LHSKAEEVLSLE----KRKQQLYTAMEERTEEIKVHKTMLASQIRYVDQERENISTEFRE 630
Query: 894 --------KPLFE-TDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEE 944
K +E V+ E ++ T A ++A E +Q + ++ + +AE+
Sbjct: 631 RLSKIEKLKNRYEILTVVMLPPEGEEEKTQAYYVIKAAQEKEELQREGDCLDAKINKAEK 690
Query: 945 K---FEDAYEKLHHTLIKNKDLEELVMTSRKE------SKEEKENQDER-EVKEEEEQQE 994
+ E+ + L+ K + V S E +E+K DE+ K+ + ++
Sbjct: 691 EIYALENTLQVLNSCNNNYKQSFKKVTPSSDEYELKIQLEEQKRAVDEKYRYKQRQIREL 750
Query: 995 EEEVRSAENS 1004
+E+++S EN+
Sbjct: 751 QEDIQSMENT 760
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 56.6 bits (135), Expect = 1e-07
Identities = 176/882 (19%), Positives = 356/882 (40%), Gaps = 97/882 (10%)
Query: 200 LTDSENRLLLFPSMKPNK-RVEVAQLNDVMDTMLERAGVENQEYTGPTKMHKLLHILKKE 258
++++ N+L S + NK R + A+L ++ + E+ G QE + LK +
Sbjct: 433 VSNTTNQLESKQSAELNKLRQDYARL---VNELTEKTGKLQQEEVQKKNAEQAATQLKVQ 489
Query: 259 QTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQR 318
+ E+ + A+ ++ ++V +++ LV+++ ++QR
Sbjct: 490 LQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQR 549
Query: 319 ILEELYNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNAEKNAKIV-EEYHD 377
+++ + + + + + E ++ D+ E KA + + A+ +A ++ EE H
Sbjct: 550 LMQLMESEQKRVNK--EESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHK 607
Query: 378 LYTLQRERMENDMKKLVAERDIWSSATYELA---------------LKVIERNRVILARR 422
+ + ++++ L +ERD +S EL L+ + + A
Sbjct: 608 VIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHE 667
Query: 423 L-------YLNEKGWNKYTKHFIILLSNKDTEDLAL------LQKLTQKWRNLVNKL--K 467
L Y+ + + +SNK E L L+ QK + LV++ K
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNK 727
Query: 468 QEVEQME---ESTSETLKIVKD----GLIKWQEFFNEKDILSPNKGNIFNSVL-LDFKQW 519
VEQME + E LK V++ GLI+ E + + ++ V L KQ
Sbjct: 728 DVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQN 787
Query: 520 QKILNEKKEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEE 579
++ E V+ K +K ++ L E A++ L + N+ K+++ ++ E + ++E
Sbjct: 788 DQVSFASLVEELKKVIHEKDGKIKSVEELLE--AEL-LKVANKEKTVQ-DLKQEIKALKE 843
Query: 580 IIKNIQKLYKEYEIRINGD-NGYSKILPSLISSLDFCSFKLENLEFPDTPLEEW-QEIDE 637
I N+Q L K ++ I +L ++ LE E +W Q++ E
Sbjct: 844 EIGNVQ-LEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQE 902
Query: 638 KINEMKSHLDIL----LNLTGIVPQHIDVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIE 693
+ +K+H+ + L Q +++ V + ++ L + +++++
Sbjct: 903 ENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQL 962
Query: 694 LQHHMDE--LHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELD---- 747
LQ DE L S I+ + +F + LLK+ E EK G+ ELD
Sbjct: 963 LQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISER-EKEISGLWN-ELDSLKD 1020
Query: 748 AIELTRKL----YQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWI 803
A+E RK Q + K ++ + S S+ + E L+ +K KEC
Sbjct: 1021 AVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGT 1080
Query: 804 NTCSCLLSNIKGRKITLLTYEEIERLLEEEAVK--------EFIEPEIDESFKEDEEESK 855
+ +K + L +E+ LL+ E K E I ++ S ++EE+K
Sbjct: 1081 SGSE----EVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSV--EQEENK 1134
Query: 856 EDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAK--QGT 913
K+ E +K + Q S ++ +++L R E++++ + E + L E A+ + T
Sbjct: 1135 WKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRR-EREHLEMELEKAEMERST 1193
Query: 914 LAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLH------------HTLIKNK 961
+ E A + KL +N ++ A + L T+I+N
Sbjct: 1194 YVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENS 1253
Query: 962 DLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAEN 1003
D+ +S KE+ NQ ++++ + ++ + E+
Sbjct: 1254 DVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEH 1295
Score = 45.8 bits (107), Expect = 2e-04
Identities = 165/911 (18%), Positives = 362/911 (39%), Gaps = 132/911 (14%)
Query: 197 TTLLTDSENRLLLFPSMKPNKRV---EVAQLNDVMDTMLERAGVENQEYTGPTKMHKLLH 253
TTL+ + + L ++K + QL M T ER+ V T+M +
Sbjct: 328 TTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVI------TRMKDRIG 381
Query: 254 ILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRERYVQMLDQIA--RQMIDFYKDLV- 310
L+KE ++ H V + ++ K ++ QM +IA +Q +D V
Sbjct: 382 TLEKEHNVFQNKIH-------VSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVS 434
Query: 311 -TQRVMDQRILEEL----YNFKHVIEELTRELCLVRAHDVKLTKETEKAHKDLAQALLNA 365
T ++ + EL ++ ++ ELT + ++ +V+ K E+A L L A
Sbjct: 435 NTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQ-KKNAEQAATQLKVQLQEA 493
Query: 366 EKNAKIVEEYHDLYTLQRERMENDMK-KLVAERDIWSSATYELALKVIERNRVILARRLY 424
E+ + V+ Y T + E + D++ K VA+ + S +L ++ + + + R +
Sbjct: 494 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQ-LEQRLMQ 552
Query: 425 LNEKGWNKYTKHFIILLSNKDT-EDLALLQKLTQKWRNLV------NKLKQEVEQMEEST 477
L E + K + + +D E L+ Q++ + + + L +E+ ++
Sbjct: 553 LMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEK 612
Query: 478 SETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEKKE-----EFTG 532
+ +K +D L ++ K+ + N+ + + ++ Q + NE+ E
Sbjct: 613 DKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQ 672
Query: 533 DVLLSKYDTLKIIKHLQENWADIGLGIF----NRHKSLEGEMPS-----ERQYMEEIIKN 583
+ K D +++++ ++ + F +++K+L+ E+ Q +++++
Sbjct: 673 QSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQ 732
Query: 584 IQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKLENLEFPDTPL-EEWQEIDEKINEM 642
++K +E + ++ ++L + + + +L + ++ L +E Q++ K N+
Sbjct: 733 MEKCIQEKDEKLKT---VEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQ 789
Query: 643 KSHLDILLNLTGIVPQHID-VDSVS-VLQAYIFNM---------IQQWLLKIGNEINNGN 691
S ++ L ++ + + SV +L+A + + ++Q + + EI GN
Sbjct: 790 VSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI--GN 847
Query: 692 IELQHHMDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIEL 751
++L+ S +Q + NLL +Q +K E EK + D E
Sbjct: 848 VQLEKAQQLSITSKVQELQNLL----KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEE 903
Query: 752 TRKLYQYSSYLSSC-CKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWINTCSCLL 810
L + ++ K +A + K +L ++ + KE +++ + LL
Sbjct: 904 NESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLL 963
Query: 811 SNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEEN---KER 867
+++ L +IE+L ++ + P +E K E KE L E K+
Sbjct: 964 QDVQDEN--KLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDA 1021
Query: 868 AEEQPSTSTEKEKLIRFIGEDENVHSKPLF------------------------------ 897
E Q + E+++ + + + K LF
Sbjct: 1022 VEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTS 1081
Query: 898 ---ETDVLS-SWRESAKQGTLAQ----KYLEAMA----VIEHMQEKLLEVENR------- 938
E VL +E+ + TL Q KY +A +++ +Q + + EN+
Sbjct: 1082 GSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDE 1141
Query: 939 ----ARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQE 994
+Q + F + ++L +NKD+E L R+E + + ++ E++ E
Sbjct: 1142 SHKTIKQMQSSFTSSEQELERLRSENKDIENL----RREREHLEMELEKAEMERSTYVTE 1197
Query: 995 EEEVRSAENSS 1005
E+++ N +
Sbjct: 1198 VRELKAQLNET 1208
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 56.2 bits (134), Expect = 1e-07
Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 19/204 (9%)
Query: 827 ERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEEN------KERAEEQPSTSTEKEK 880
+++L EE E S E EE K K EEN K + + + +E+ K
Sbjct: 1235 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1294
Query: 881 LIRFI------------GED-ENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEH 927
R+ GE E +KP +V R + V E
Sbjct: 1295 KPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEE 1354
Query: 928 MQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVK 987
+ E E R R A++ + ++ + K + ++ +S + +E ++E+E +
Sbjct: 1355 VSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1414
Query: 988 EEEEQQEEEEVRSAENSSKSPKKG 1011
EEEE++EEEE + SKSP KG
Sbjct: 1415 EEEEEEEEEEEEDENDDSKSPGKG 1438
Score = 32.3 bits (72), Expect = 2.3
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 11/74 (14%)
Query: 831 EEEAVKEFIEPEIDESFKEDEEES----------KEDRKLQEENKERAEEQPSTSTEKEK 880
EEE KE E E +E +E+E+E+ K+ RK+ +++K R E Q + E+E+
Sbjct: 1406 EEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEER 1465
Query: 881 LIRFIGEDENVHSK 894
R I E E K
Sbjct: 1466 RKR-IAEREREREK 1478
Score = 31.2 bits (69), Expect = 5.2
Identities = 37/160 (23%), Positives = 69/160 (43%), Gaps = 26/160 (16%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
EE +R +++ + I+ + D S + +E+ + +EE +E EE+ E+E
Sbjct: 1375 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE-----EEE---- 1425
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
EDEN SK K +K L+ + Q L E E R ++
Sbjct: 1426 ---EDENDDSK------------SPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIA 1470
Query: 944 EKFEDAYEKLHHTL-IKNKDLEELVMTSRKESKEEKENQD 982
E+ E EKL + I++ + +T++ E++E ++
Sbjct: 1471 ER-EREREKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1509
Score = 30.8 bits (68), Expect = 6.7
Identities = 55/274 (20%), Positives = 114/274 (41%), Gaps = 43/274 (15%)
Query: 771 TAMALSKSTNSHKNATEDLYEVDKL--KKECYEWINTCSCLLSNIKGRKITLLTYEEIER 828
T M L + A+ VDKL K++ + + + K + + T ++++
Sbjct: 862 TIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQD 921
Query: 829 LLEEEAVKEFIEPEIDESFKEDEEESK---EDRKLQEENKERA---EEQPSTST------ 876
L + A K + + DE+ ++D+++SK E++K + K++ E+Q +S+
Sbjct: 922 GLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKL 981
Query: 877 -EKEKLIRF------------IGE--DENVHSKPLFETDVLSSWRESAK------QGTLA 915
E+E++ F GE + + K + D LS + E + +
Sbjct: 982 PEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSED 1041
Query: 916 QKYLEAMAVIEHMQEKLLEVENRARQ-----AEEKF---EDAYEKLHHTLIKNKDLEELV 967
+K E + KLL +R RQ EK+ ED L + + E
Sbjct: 1042 KKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRN 1101
Query: 968 MTSRKESKEEKENQDEREVKEEEEQQEEEEVRSA 1001
++S++ +KE + + +E E ++++ R++
Sbjct: 1102 LSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTS 1135
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 56.2 bits (134), Expect = 1e-07
Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 19/204 (9%)
Query: 827 ERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEEN------KERAEEQPSTSTEKEK 880
+++L EE E S E EE K K EEN K + + + +E+ K
Sbjct: 1273 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1332
Query: 881 LIRFI------------GED-ENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEH 927
R+ GE E +KP +V R + V E
Sbjct: 1333 KPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEE 1392
Query: 928 MQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVK 987
+ E E R R A++ + ++ + K + ++ +S + +E ++E+E +
Sbjct: 1393 VSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1452
Query: 988 EEEEQQEEEEVRSAENSSKSPKKG 1011
EEEE++EEEE + SKSP KG
Sbjct: 1453 EEEEEEEEEEEEDENDDSKSPGKG 1476
Score = 32.3 bits (72), Expect = 2.3
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 11/74 (14%)
Query: 831 EEEAVKEFIEPEIDESFKEDEEES----------KEDRKLQEENKERAEEQPSTSTEKEK 880
EEE KE E E +E +E+E+E+ K+ RK+ +++K R E Q + E+E+
Sbjct: 1444 EEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEER 1503
Query: 881 LIRFIGEDENVHSK 894
R I E E K
Sbjct: 1504 RKR-IAEREREREK 1516
Score = 31.2 bits (69), Expect = 5.2
Identities = 37/160 (23%), Positives = 69/160 (43%), Gaps = 26/160 (16%)
Query: 824 EEIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIR 883
EE +R +++ + I+ + D S + +E+ + +EE +E EE+ E+E
Sbjct: 1413 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE-----EEE---- 1463
Query: 884 FIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAE 943
EDEN SK K +K L+ + Q L E E R ++
Sbjct: 1464 ---EDENDDSK------------SPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIA 1508
Query: 944 EKFEDAYEKLHHTL-IKNKDLEELVMTSRKESKEEKENQD 982
E+ E EKL + I++ + +T++ E++E ++
Sbjct: 1509 ER-EREREKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1547
Score = 30.8 bits (68), Expect = 6.7
Identities = 55/274 (20%), Positives = 114/274 (41%), Gaps = 43/274 (15%)
Query: 771 TAMALSKSTNSHKNATEDLYEVDKL--KKECYEWINTCSCLLSNIKGRKITLLTYEEIER 828
T M L + A+ VDKL K++ + + + K + + T ++++
Sbjct: 900 TIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQD 959
Query: 829 LLEEEAVKEFIEPEIDESFKEDEEESK---EDRKLQEENKERA---EEQPSTST------ 876
L + A K + + DE+ ++D+++SK E++K + K++ E+Q +S+
Sbjct: 960 GLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKL 1019
Query: 877 -EKEKLIRF------------IGE--DENVHSKPLFETDVLSSWRESAK------QGTLA 915
E+E++ F GE + + K + D LS + E + +
Sbjct: 1020 PEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSED 1079
Query: 916 QKYLEAMAVIEHMQEKLLEVENRARQ-----AEEKF---EDAYEKLHHTLIKNKDLEELV 967
+K E + KLL +R RQ EK+ ED L + + E
Sbjct: 1080 KKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRN 1139
Query: 968 MTSRKESKEEKENQDEREVKEEEEQQEEEEVRSA 1001
++S++ +KE + + +E E ++++ R++
Sbjct: 1140 LSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTS 1173
>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
Length = 1646
Score = 55.5 bits (132), Expect = 3e-07
Identities = 56/243 (23%), Positives = 102/243 (41%), Gaps = 38/243 (15%)
Query: 782 HKNATEDLYEVDKLKKECYEWINTC------SCLLSNIKGRKITLLTYEEIERLLEE--- 832
H +D + K + EC+ + T + +L + L Y + + E+
Sbjct: 723 HLEKVKDYLKNMKSRYECFHTLLTKEVMEYPAIMLKELNSYSSALSQYFFVREIFEQNLA 782
Query: 833 -EAVKEFIEPEIDESFKEDEEESKEDRKLQ--EENKERAEEQPSTSTEKEKLIRFIGEDE 889
E + +F +PE E K ++ K+ RK Q +E+ R+EE S+ T + + + E+
Sbjct: 783 GEVIFKFRQPEAHE--KPSQKRVKKLRKKQGSKEDMTRSEESISSGTSTARSVEEVEEEN 840
Query: 890 NVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDA 949
+ + +VL ++S + + ++ +E MQ VE
Sbjct: 841 DQEMESFITEEVLGQQKKSPLHAKMDESKEGSIQGLEEMQ-----VEREGSL-------- 887
Query: 950 YEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ-QEEEEVRSAENSSKSP 1008
N L E + + E KEE E +DE+E +EEEE+ +EE+E + A+ +S
Sbjct: 888 ----------NPSLNEENVKGQGEKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQESL 937
Query: 1009 KKG 1011
G
Sbjct: 938 SVG 940
Score = 35.0 bits (79), Expect = 0.36
Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Query: 830 LEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEEN--KERAEEQPSTSTEKEK 880
L EE VK E + + ++++EE +E+ KL+EE KE EEQ S S +E+
Sbjct: 891 LNEENVKGQGEKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQESLSVGEEE 943
Score = 30.4 bits (67), Expect = 8.8
Identities = 15/46 (32%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 845 ESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDEN 890
E +E EEE +++ + +EE E +E+ E+E L +GE+E+
Sbjct: 901 EKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQESL--SVGEEED 944
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 55.1 bits (131), Expect = 3e-07
Identities = 44/192 (22%), Positives = 89/192 (46%), Gaps = 10/192 (5%)
Query: 825 EIERLLEEEAV---KEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKL 881
E ER+ E E +E + E +E +E EE+ +E + E +E+ +EQ E+E+
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE- 61
Query: 882 IRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMA--VIEHMQEKLLEVENRA 939
+ ++E + + W + + ++ E +E M+EK E +
Sbjct: 62 -KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
Query: 940 RQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVR 999
++ EEK ++ E + K ++ EE + ++ +E++E E +EE+ Q +EE++R
Sbjct: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE---QEEKMQGQEEKMR 177
Query: 1000 SAENSSKSPKKG 1011
E + +G
Sbjct: 178 DVEPAGGEAGEG 189
Score = 53.5 bits (127), Expect = 1e-06
Identities = 36/159 (22%), Positives = 76/159 (47%), Gaps = 13/159 (8%)
Query: 848 KEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRE 907
+E+E + ++K++EE + E++ ++EK+ E++ + + W +
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMRE--QEEKMWEQEEKMQEQEEKMWEQ 59
Query: 908 SAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELV 967
K +K E + E +EK+ E + R R+ EE+ + +K+ + K
Sbjct: 60 EEKMWEQEEKMWEQQRLPE-QKEKMWEQDERLREKEERMRE--QKMWQQVEK-------- 108
Query: 968 MTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENSSK 1006
M +K+++EEK + E +++E+EE E+E + E K
Sbjct: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147
Score = 48.1 bits (113), Expect = 4e-05
Identities = 46/193 (23%), Positives = 86/193 (44%), Gaps = 30/193 (15%)
Query: 824 EEIERLLE-EEAVKEFIEP--EIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEK 880
E+ E++ E EE ++E E E +E +E EE+ E + E +E+ EQ +KEK
Sbjct: 23 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK 82
Query: 881 LI----RFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVE 936
+ R ++E + + +++ + RE K T +K E ++ +E + E E
Sbjct: 83 MWEQDERLREKEERMREQKMWQQ--VEKMREKKK--TQEEKMQEQEEKMQEQEEMMWEQE 138
Query: 937 NRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEE 996
+ ++ EEK + EK+ +EEK + E +++ +EE+ +
Sbjct: 139 EKMQEQEEKMWEQEEKM-------------------REQEEKMREQEEKMQGQEEKMRDV 179
Query: 997 EVRSAENSSKSPK 1009
E E SP+
Sbjct: 180 EPAGGEAGEGSPQ 192
Score = 41.6 bits (96), Expect = 0.004
Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 906 RESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEE 965
RE + +K E ++ +EK+ E E + R+ EEK + EK+ K + EE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 966 LVMTSRK---------ESKEEKENQDEREVKEEEEQQEEEEVRSAENSSKSPKK 1010
+ + E KE+ QDER ++E+EE+ E+++ + KK
Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDER-LREKEERMREQKMWQQVEKMREKKK 114
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 54.7 bits (130), Expect = 4e-07
Identities = 173/867 (19%), Positives = 343/867 (39%), Gaps = 138/867 (15%)
Query: 170 TDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMD 229
T+ L EEF + S G + DS L + S K+ E+ +LN ++
Sbjct: 131 TNLLREEEFGVDDSYSEQGAQ-----------DSPTHLEMMESELAGKQHEIEELNRELE 179
Query: 230 TMLERAGVENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRE 289
M G E G ++ + +K+ I I Q++ + +
Sbjct: 180 EMRVTYGTE-----GLQQLQEFEAAIKQRDGI--------ITQLTANLQQARREKDETMR 226
Query: 290 RYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTK 349
++++ +Q + I F + ++ + + + +++ + D L +
Sbjct: 227 EFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQD-HLLE 285
Query: 350 ETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELAL 409
+ +K +D + ++ K+ E D +++EN K+ + E++ + EL
Sbjct: 286 DYQKKKEDFTMQISFLQEKIKVYEMEQD------KKVENSNKEEIQEKE---TIIEELNT 336
Query: 410 KVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQE 469
K+IE + + L L +K L+ D L +++ QK + + N +K E
Sbjct: 337 KIIEEEK----KTLELKDK------------LTTADKLLGELQEQIVQKNQEIKN-MKLE 379
Query: 470 V---EQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEK 526
+ +Q E +SE +K + G ++ + N KD S + +I + + ++ + L +
Sbjct: 380 LTNSKQKERQSSEEIKQLM-GTVEELQKRNHKD--SQFETDIVQRMEQETQRKLEQLRAE 436
Query: 527 KEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSE-RQYM-----EEI 580
+E G ++ L I +H+ + + RHK GEM + R Y E+
Sbjct: 437 LDEMYGQQIVQMKQEL-IRQHMAQMEE-----MKTRHK---GEMENALRSYSNITVNEDQ 487
Query: 581 IKNIQKLYKEYEIRINGDNGYSKILPSLISSL--DFCSFK--LENL-EFPDTPLEEWQEI 635
IK + E I++ N + L + + + C+ + LE+L E E+ Q
Sbjct: 488 IKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRA 547
Query: 636 DEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQ---QWLLKIGNEINNGNI 692
+ I E +S L+ H + +V L+A I + + + LK E+ N I
Sbjct: 548 RQTIAEQESKLN---------EAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKI 598
Query: 693 ELQHH-------MDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLE 745
+L+ +D + S + L ++ F+ ++ L KL+E+ +H I + +L+
Sbjct: 599 KLEMLEKEKNAVLDRMAESQEAELERLRTQLL--FSHEEELSKLKEDLEIEHRINIEKLK 656
Query: 746 LDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWINT 805
D + + K Q L + + M K N + + E+ KLK +N+
Sbjct: 657 -DNLGIHYK--QQIDGLQNEMSQKIETMQFEKD-NLITKQNQLILEISKLKDLQQSLVNS 712
Query: 806 CSCLLSNIKGRKITLLTYE---EIERLLEEEAVKEFIEPEIDE----------SFKEDEE 852
K ++TL E EIE L +EE K +E E+ E KE E
Sbjct: 713 --------KSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 764
Query: 853 ESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQ- 911
+ +E E +++ T + K+ + ++E + +F + S ++S +
Sbjct: 765 DLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERL----IFLDSIKSKSKDSVWEK 820
Query: 912 --GTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMT 969
L ++ + + E++ + N AE+ FE Y++L E +
Sbjct: 821 EIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQE--------EYACLL 872
Query: 970 SRKESKEEKENQDEREVKEEEEQQEEE 996
K+ E+ +N+ E E K + + EE
Sbjct: 873 KVKDDLEDSKNKQELEYKSKLKALNEE 899
Score = 40.8 bits (94), Expect = 0.007
Identities = 164/841 (19%), Positives = 337/841 (40%), Gaps = 161/841 (19%)
Query: 284 LSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAH 343
L + +++ + RQ + + L Q + +R+ EE + + EL++ ++ +
Sbjct: 1868 LEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGY 1927
Query: 344 -DVKLTKETEKAHKD-----LAQALLNA-------EKNAKIVEEYHDLYTLQRERMENDM 390
D K E + K L Q LL A E + ++E +L + Q+E M+ +
Sbjct: 1928 ADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEA 1987
Query: 391 ----KKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDT 446
++L+ E + E+ + E+ R L +++ E + FI L K+T
Sbjct: 1988 GPVEQQLLQETEKLMKEKLEVQCQA-EKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNT 2046
Query: 447 EDLAL------LQKLTQKWRNLVNK-----------LKQEVEQMEESTSETLKIVKDGLI 489
E + L L+K +K R +++ +QE++++E+ LK+V
Sbjct: 2047 ELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQ----LKVVPRFQP 2102
Query: 490 KWQEFFNEKDILSPN---KGNIFNSVLLDFKQWQKILNEKKEEFTG---------DVLLS 537
+ E + L+ + K + + +LL +Q Q+ + E+ EE LL
Sbjct: 2103 ISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLV 2162
Query: 538 KYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRING 597
DT + + E+ G SLE ++ +ER ++ K I L ++ E
Sbjct: 2163 SADTFQKV----EDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLE----- 2213
Query: 598 DNGYSKILPSLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVP 657
+ + L + + +LE + T QE++++ K ++ L G+
Sbjct: 2214 --QFREELENKNEEVQQLHMQLEIQKKESTT--RLQELEQENKLFKDDMEKL----GLAI 2265
Query: 658 QHIDVDSVSVLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMV---NLLI 714
+ D S Q +F Q + + EI+ N ++ +L I+ ++ N LI
Sbjct: 2266 KESDAMSTQD-QHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELI 2324
Query: 715 LMIPN-----FTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLS------ 763
+ +DQ+C+ + EE E+ + + +L+ + + +K + LS
Sbjct: 2325 RDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSL 2384
Query: 764 -------------------SCCKGMVTAMALSKSTNSHKN-ATEDLYEVDKLKKECYEWI 803
+ + M + K TN N T++L+ + K ++E E I
Sbjct: 2385 KHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSL-KRERESVEKI 2443
Query: 804 -----NTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEES---K 855
N+ + + ++ K E+E +L E+A+K +SF+E+ + S
Sbjct: 2444 QSIPENSVNVAIDHLSKDK------PELEVVLTEDALKSLENQTYFKSFEENGKGSIINL 2497
Query: 856 EDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSS--------WRE 907
E R LQ E+ A++ T K + +++ + FET++L E
Sbjct: 2498 ETRLLQLESTVSAKDLELTQCYK--------QIKDMQEQGQFETEMLQKKIVNLQKIVEE 2549
Query: 908 SAKQGTLAQKYLEAM-----------AVIEHMQEKLLEVENRARQAE------------E 944
++Q LEA+ + + ++ N+ R+ E
Sbjct: 2550 KVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRIS 2609
Query: 945 KFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKE--EEEQQEEEEVRSAE 1002
+ E ++H +LI K E++ + + ++EK+ + +++ E E++Q+E+E+ RS +
Sbjct: 2610 ELESQVVEMHTSLILEK--EQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQ 2667
Query: 1003 N 1003
+
Sbjct: 2668 D 2668
Score = 39.3 bits (90), Expect = 0.019
Identities = 44/178 (24%), Positives = 93/178 (52%), Gaps = 22/178 (12%)
Query: 842 EIDESFKEDEEESKEDRKLQEENKE-RAEEQPSTSTEKEKLIRFIGEDENV--HSKPLFE 898
E DE+ +E E +++ +KLQ + ++ +A E ST + + + H + L E
Sbjct: 220 EKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEE 279
Query: 899 TD-VLSSWRESAKQGTLAQKYL-EAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHT 956
D +L +++ + T+ +L E + V E Q+K +VEN ++ ++ E E+L+
Sbjct: 280 QDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDK--KVENSNKEEIQEKETIIEELNTK 337
Query: 957 LI----KNKDLEELVMTSRK---ESKEE--KENQDEREVK------EEEEQQEEEEVR 999
+I K +L++ + T+ K E +E+ ++NQ+ + +K +++E+Q EE++
Sbjct: 338 IIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIK 395
Score = 38.5 bits (88), Expect = 0.032
Identities = 57/312 (18%), Positives = 122/312 (39%), Gaps = 36/312 (11%)
Query: 728 KLEEESAEKHDIGVAR-LELDAIELTRKLYQYSSYLSSCCKGMVTAMAL--SKSTNSHKN 784
K + S+ KHD+ L +D + S + S T M S SH+
Sbjct: 38 KKRKTSSSKHDVSAHHDLNIDQSQCNEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQ 97
Query: 785 --ATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEE--IERLLEEEAVK---- 836
+ E E+ +C +N CS ++ G+ LL EE ++ E+ +
Sbjct: 98 GFSVELESEISTTADDCSSEVNGCSFVMRT--GKPTNLLREEEFGVDDSYSEQGAQDSPT 155
Query: 837 --EFIEPEIDESFKEDEEESKEDRKLQ----EENKERAEEQPSTSTEKEKLIRFIGEDEN 890
E +E E+ E EE ++E +++ E ++ +E + +++ +I + N
Sbjct: 156 HLEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQL--TAN 213
Query: 891 VHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQ---------------EKLLEV 935
+ + + + + E +Q Q + + E ++ +++L
Sbjct: 214 LQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTH 273
Query: 936 ENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEE 995
+ + + + ED +K ++ L+E + E ++ EN ++ E++E+E EE
Sbjct: 274 QQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEE 333
Query: 996 EEVRSAENSSKS 1007
+ E K+
Sbjct: 334 LNTKIIEEEKKT 345
Score = 35.0 bits (79), Expect = 0.36
Identities = 34/176 (19%), Positives = 71/176 (40%), Gaps = 17/176 (9%)
Query: 832 EEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENV 891
EE + + +D S K S R E + + + T E + + G D
Sbjct: 1746 EETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSD--- 1802
Query: 892 HSKPLFETDVLSSWRESAKQGT-LAQKYLEA----MAVIEHMQEKLLEVENRARQAEEKF 946
+ ++ W + ++GT L+Q+ + + + +E +L + +R + A EK
Sbjct: 1803 -----MPRNDINMWSKVTEEGTELSQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKL 1857
Query: 947 EDAYEK----LHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEV 998
+A + L H + +L ++E+ E + Q+E + EE + E++
Sbjct: 1858 LEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQL 1913
Score = 35.0 bits (79), Expect = 0.36
Identities = 62/320 (19%), Positives = 136/320 (42%), Gaps = 35/320 (10%)
Query: 716 MIPNFTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLSSCCKGMVTAMAL 775
+I + D+ L E + EK DI + RLE + + + +L + + +
Sbjct: 1923 VIDGYADEKTLF--ERQIQEKTDI-IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ 1979
Query: 776 SKSTNSHKNATED--LYEVDKLKKECYEWINTCSCLLSNIKG------RKITLLTYEEIE 827
++ + E L E +KL KE E C ++ + + + E++
Sbjct: 1980 KEAMKAEAGPVEQQLLQETEKLMKEKLE----VQCQAEKVRDDLQKQVKALEIDVEEQVS 2035
Query: 828 RLLEEEAVKEFIEPEIDESFKEDEEESKEDRK-LQEENKERAEEQPSTSTEKEKL---IR 883
R +E E K ++ + + E++ ++ RK L E+ +R E+ E +KL ++
Sbjct: 2036 RFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLK 2095
Query: 884 FIGEDENVHSKPLFETDVLSSW--RESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQ 941
+ + + E + L++ ++ K L + I+ E++ ++E R R+
Sbjct: 2096 VVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRE 2155
Query: 942 AEEK-------FEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQ-- 992
E+ F+ ++ H ++ K EL + + +++ + ++ E+E+ EEQ
Sbjct: 2156 LEQALLVSADTFQKVEDRKHFGAVEAKP--ELSLEVQLQAERDAIDRKEKEITNLEEQLE 2213
Query: 993 QEEEEVRSAENSSKSPKKGH 1012
Q EE+ EN ++ ++ H
Sbjct: 2214 QFREEL---ENKNEEVQQLH 2230
Score = 33.5 bits (75), Expect = 1.0
Identities = 48/213 (22%), Positives = 91/213 (42%), Gaps = 19/213 (8%)
Query: 803 INTCSCLLSNIKGRKITLLTYEEIER----LLE---EEAVKEFIEPEIDESFKED----- 850
++ L + + GRKITL +E E+ LLE ++ + +E +++ S +D
Sbjct: 3091 LSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATEL 3150
Query: 851 -EEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESA 909
E+ S E + E E A+ + T + + + E E + +TD + ++
Sbjct: 3151 QEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTL 3210
Query: 910 KQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMT 969
+ +K E +E + KL E R + E+ ED L +N L L++
Sbjct: 3211 --ASEQKKSRELQWALEKEKAKLGRSEERDK---EELEDLKFSLESQKQRNLQL-NLLLE 3264
Query: 970 SRKESKEEKENQDEREVKEEEEQQEEEEVRSAE 1002
+K+ E + + E + + Q EE+ R+ E
Sbjct: 3265 QQKQLLNESQQKIESQRMLYDAQLSEEQGRNLE 3297
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 54.7 bits (130), Expect = 4e-07
Identities = 173/867 (19%), Positives = 343/867 (39%), Gaps = 138/867 (15%)
Query: 170 TDTLIPEEFHIVSSTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEVAQLNDVMD 229
T+ L EEF + S G + DS L + S K+ E+ +LN ++
Sbjct: 131 TNLLREEEFGVDDSYSEQGAQ-----------DSPTHLEMMESELAGKQHEIEELNRELE 179
Query: 230 TMLERAGVENQEYTGPTKMHKLLHILKKEQTIYNMIFHELIRQVSVDCADRGELLSKVRE 289
M G E G ++ + +K+ I I Q++ + +
Sbjct: 180 EMRVTYGTE-----GLQQLQEFEAAIKQRDGI--------ITQLTANLQQARREKDETMR 226
Query: 290 RYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAHDVKLTK 349
++++ +Q + I F + ++ + + + +++ + D L +
Sbjct: 227 EFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQD-HLLE 285
Query: 350 ETEKAHKDLAQALLNAEKNAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELAL 409
+ +K +D + ++ K+ E D +++EN K+ + E++ + EL
Sbjct: 286 DYQKKKEDFTMQISFLQEKIKVYEMEQD------KKVENSNKEEIQEKE---TIIEELNT 336
Query: 410 KVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDTEDLALLQKLTQKWRNLVNKLKQE 469
K+IE + + L L +K L+ D L +++ QK + + N +K E
Sbjct: 337 KIIEEEK----KTLELKDK------------LTTADKLLGELQEQIVQKNQEIKN-MKLE 379
Query: 470 V---EQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQWQKILNEK 526
+ +Q E +SE +K + G ++ + N KD S + +I + + ++ + L +
Sbjct: 380 LTNSKQKERQSSEEIKQLM-GTVEELQKRNHKD--SQFETDIVQRMEQETQRKLEQLRAE 436
Query: 527 KEEFTGDVLLSKYDTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSE-RQYM-----EEI 580
+E G ++ L I +H+ + + RHK GEM + R Y E+
Sbjct: 437 LDEMYGQQIVQMKQEL-IRQHMAQMEE-----MKTRHK---GEMENALRSYSNITVNEDQ 487
Query: 581 IKNIQKLYKEYEIRINGDNGYSKILPSLISSL--DFCSFK--LENL-EFPDTPLEEWQEI 635
IK + E I++ N + L + + + C+ + LE+L E E+ Q
Sbjct: 488 IKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRA 547
Query: 636 DEKINEMKSHLDILLNLTGIVPQHIDVDSVSVLQAYIFNMIQ---QWLLKIGNEINNGNI 692
+ I E +S L+ H + +V L+A I + + + LK E+ N I
Sbjct: 548 RQTIAEQESKLN---------EAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKI 598
Query: 693 ELQHH-------MDELHISMIQWMVNLLILMIPNFTDQDCLLKLEEESAEKHDIGVARLE 745
+L+ +D + S + L ++ F+ ++ L KL+E+ +H I + +L+
Sbjct: 599 KLEMLEKEKNAVLDRMAESQEAELERLRTQLL--FSHEEELSKLKEDLEIEHRINIEKLK 656
Query: 746 LDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECYEWINT 805
D + + K Q L + + M K N + + E+ KLK +N+
Sbjct: 657 -DNLGIHYK--QQIDGLQNEMSQKIETMQFEKD-NLITKQNQLILEISKLKDLQQSLVNS 712
Query: 806 CSCLLSNIKGRKITLLTYE---EIERLLEEEAVKEFIEPEIDE----------SFKEDEE 852
K ++TL E EIE L +EE K +E E+ E KE E
Sbjct: 713 --------KSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 764
Query: 853 ESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQ- 911
+ +E E +++ T + K+ + ++E + +F + S ++S +
Sbjct: 765 DLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERL----IFLDSIKSKSKDSVWEK 820
Query: 912 --GTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMT 969
L ++ + + E++ + N AE+ FE Y++L E +
Sbjct: 821 EIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQE--------EYACLL 872
Query: 970 SRKESKEEKENQDEREVKEEEEQQEEE 996
K+ E+ +N+ E E K + + EE
Sbjct: 873 KVKDDLEDSKNKQELEYKSKLKALNEE 899
Score = 39.3 bits (90), Expect = 0.019
Identities = 44/178 (24%), Positives = 93/178 (52%), Gaps = 22/178 (12%)
Query: 842 EIDESFKEDEEESKEDRKLQEENKE-RAEEQPSTSTEKEKLIRFIGEDENV--HSKPLFE 898
E DE+ +E E +++ +KLQ + ++ +A E ST + + + H + L E
Sbjct: 220 EKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEE 279
Query: 899 TD-VLSSWRESAKQGTLAQKYL-EAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHT 956
D +L +++ + T+ +L E + V E Q+K +VEN ++ ++ E E+L+
Sbjct: 280 QDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDK--KVENSNKEEIQEKETIIEELNTK 337
Query: 957 LI----KNKDLEELVMTSRK---ESKEE--KENQDEREVK------EEEEQQEEEEVR 999
+I K +L++ + T+ K E +E+ ++NQ+ + +K +++E+Q EE++
Sbjct: 338 IIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIK 395
Score = 38.9 bits (89), Expect = 0.025
Identities = 163/832 (19%), Positives = 337/832 (40%), Gaps = 151/832 (18%)
Query: 284 LSKVRERYVQMLDQIARQMIDFYKDLVTQRVMDQRILEELYNFKHVIEELTRELCLVRAH 343
L + +++ + RQ + + L Q + +R+ EE + + EL++ ++ +
Sbjct: 1868 LEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGY 1927
Query: 344 -DVKLTKETEKAHKD-----LAQALLNA-------EKNAKIVEEYHDLYTLQRERMENDM 390
D K E + K L Q LL A E + ++E +L + Q+E M+ +
Sbjct: 1928 ADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEA 1987
Query: 391 ----KKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHFIILLSNKDT 446
++L+ E + E+ + E+ R L +++ E + FI L K+T
Sbjct: 1988 GPVEQQLLQETEKLMKEKLEVQCQA-EKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNT 2046
Query: 447 EDLAL------LQKLTQKWRNLVNK-----------LKQEVEQMEESTSETLKIVKDGLI 489
E + L L+K +K R +++ +QE++++E+ LK+V
Sbjct: 2047 ELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQ----LKVVPRFQP 2102
Query: 490 KWQEFFNEKDILSPN---KGNIFNSVLLDFKQWQKILNEKKEEFTGDVLLSKYDTLKIIK 546
+ E + L+ + K + + +LL +Q Q+ + E+ EE + L + L+
Sbjct: 2103 ISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEI--EKLEFRVRELEQAL 2160
Query: 547 HLQENWADIGLGIFNRHKSLEGEMPSERQYMEEIIKNIQKLYKEYEIRINGDNGYSKILP 606
L E+ G SLE ++ +ER ++ K I L ++ E + + L
Sbjct: 2161 -LVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLE-------QFREELE 2212
Query: 607 SLISSLDFCSFKLENLEFPDTPLEEWQEIDEKINEMKSHLDILLNLTGIVPQHIDVDSVS 666
+ + +LE + T QE++++ K ++ L G+ + D S
Sbjct: 2213 NKNEEVQQLHMQLEIQKKESTT--RLQELEQENKLFKDDMEKL----GLAIKESDAMSTQ 2266
Query: 667 VLQAYIFNMIQQWLLKIGNEINNGNIELQHHMDELHISMIQWMV---NLLILMIPN---- 719
Q +F Q + + EI+ N ++ +L I+ ++ N LI +
Sbjct: 2267 D-QHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIEC 2325
Query: 720 -FTDQDCLLKLEEESAEKHDIGVARLELDAIELTRKLYQYSSYLS--------------- 763
+DQ+C+ + EE E+ + + +L+ + + +K + LS
Sbjct: 2326 LMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIA 2385
Query: 764 ----------SCCKGMVTAMALSKSTNSHKN-ATEDLYEVDKLKKECYEWI-----NTCS 807
+ + M + K TN N T++L+ + K ++E E I N+ +
Sbjct: 2386 EKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSL-KRERESVEKIQSIPENSVN 2444
Query: 808 CLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPEIDESFKEDEEES---KEDRKLQEEN 864
+ ++ K E+E +L E+A+K +SF+E+ + S E R LQ E+
Sbjct: 2445 VAIDHLSKDK------PELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLES 2498
Query: 865 KERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSS--------WRESAKQGTLAQ 916
A++ T K + +++ + FET++L E ++Q
Sbjct: 2499 TVSAKDLELTQCYK--------QIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQ 2550
Query: 917 KYLEAM-----------AVIEHMQEKLLEVENRARQAE------------EKFEDAYEKL 953
LEA+ + + ++ N+ R+ E + E ++
Sbjct: 2551 IQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEM 2610
Query: 954 HHTLIKNKDLEELVMTSRKESKEEKENQDEREVKE--EEEQQEEEEVRSAEN 1003
H +LI K E++ + + ++EK+ + +++ E E++Q+E+E+ RS ++
Sbjct: 2611 HTSLILEK--EQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQD 2660
Score = 38.5 bits (88), Expect = 0.032
Identities = 57/312 (18%), Positives = 122/312 (39%), Gaps = 36/312 (11%)
Query: 728 KLEEESAEKHDIGVAR-LELDAIELTRKLYQYSSYLSSCCKGMVTAMAL--SKSTNSHKN 784
K + S+ KHD+ L +D + S + S T M S SH+
Sbjct: 38 KKRKTSSSKHDVSAHHDLNIDQSQCNEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQ 97
Query: 785 --ATEDLYEVDKLKKECYEWINTCSCLLSNIKGRKITLLTYEE--IERLLEEEAVK---- 836
+ E E+ +C +N CS ++ G+ LL EE ++ E+ +
Sbjct: 98 GFSVELESEISTTADDCSSEVNGCSFVMRT--GKPTNLLREEEFGVDDSYSEQGAQDSPT 155
Query: 837 --EFIEPEIDESFKEDEEESKEDRKLQ----EENKERAEEQPSTSTEKEKLIRFIGEDEN 890
E +E E+ E EE ++E +++ E ++ +E + +++ +I + N
Sbjct: 156 HLEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQL--TAN 213
Query: 891 VHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQ---------------EKLLEV 935
+ + + + + E +Q Q + + E ++ +++L
Sbjct: 214 LQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTH 273
Query: 936 ENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEE 995
+ + + + ED +K ++ L+E + E ++ EN ++ E++E+E EE
Sbjct: 274 QQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEE 333
Query: 996 EEVRSAENSSKS 1007
+ E K+
Sbjct: 334 LNTKIIEEEKKT 345
Score = 35.0 bits (79), Expect = 0.36
Identities = 34/176 (19%), Positives = 71/176 (40%), Gaps = 17/176 (9%)
Query: 832 EEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENV 891
EE + + +D S K S R E + + + T E + + G D
Sbjct: 1746 EETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSD--- 1802
Query: 892 HSKPLFETDVLSSWRESAKQGT-LAQKYLEA----MAVIEHMQEKLLEVENRARQAEEKF 946
+ ++ W + ++GT L+Q+ + + + +E +L + +R + A EK
Sbjct: 1803 -----MPRNDINMWSKVTEEGTELSQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKL 1857
Query: 947 EDAYEK----LHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEV 998
+A + L H + +L ++E+ E + Q+E + EE + E++
Sbjct: 1858 LEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQL 1913
Score = 33.5 bits (75), Expect = 1.0
Identities = 48/213 (22%), Positives = 91/213 (42%), Gaps = 19/213 (8%)
Query: 803 INTCSCLLSNIKGRKITLLTYEEIER----LLE---EEAVKEFIEPEIDESFKED----- 850
++ L + + GRKITL +E E+ LLE ++ + +E +++ S +D
Sbjct: 3083 LSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATEL 3142
Query: 851 -EEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESA 909
E+ S E + E E A+ + T + + + E E + +TD + ++
Sbjct: 3143 QEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTL 3202
Query: 910 KQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTLIKNKDLEELVMT 969
+ +K E +E + KL E R + E+ ED L +N L L++
Sbjct: 3203 --ASEQKKSRELQWALEKEKAKLGRSEERDK---EELEDLKFSLESQKQRNLQL-NLLLE 3256
Query: 970 SRKESKEEKENQDEREVKEEEEQQEEEEVRSAE 1002
+K+ E + + E + + Q EE+ R+ E
Sbjct: 3257 QQKQLLNESQQKIESQRMLYDAQLSEEQGRNLE 3289
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 54.7 bits (130), Expect = 4e-07
Identities = 166/786 (21%), Positives = 316/786 (40%), Gaps = 118/786 (15%)
Query: 317 QRILEELYNFKHVIEELTRELCLVRA--------HDVK-LTKETEKAHKDLAQALLNAEK 367
+++ +E + K I++L E LV++ H VK LT+E E ++D+++ +
Sbjct: 953 RKLEDECFELKKEIDDL--ETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKL----NR 1006
Query: 368 NAKIVEEYHDLYTLQRERMENDMKKLVAERDIWSSATYELALKVIERNRVI--------- 418
AK+V+E H TL ME + +++ ++ + +E+ R
Sbjct: 1007 AAKVVQEAHQ-QTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELH 1065
Query: 419 -LARRLYLNEKGWNKYT---KHFIILLSNKDTE----------DLALLQKLTQKWRNLVN 464
L L LN + +H L K+ E + L+ +L + + L
Sbjct: 1066 KLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQT 1125
Query: 465 KLKQEVEQMEESTSETLKIVKDGLIKWQEFFNEKDILSPNKGNIFNSVLLDFKQ---WQK 521
++K E++E + K+ ++ Q+ + + L G+ + + KQ +QK
Sbjct: 1126 QIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQK 1185
Query: 522 ILNEKKE-----EFTGDVLLSKY-DTLKIIKHLQENWADIGLGIFNRHKSLEGEMPSERQ 575
+ + +E E T L ++ D+L ++ EN + + L+ E+
Sbjct: 1186 LHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLT 1245
Query: 576 YMEEIIK---NIQKLYKEYEIRINGDNGYSKILPSLISSLDFCSFKL--ENLEFPDTPLE 630
+E++ + N +KL YE R++ + L + L KL E+ EF LE
Sbjct: 1246 RVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRR-LE 1304
Query: 631 EWQEIDEKINEMKSHLDILL-NLTGIVPQHIDVDSVSVLQAYIFNMIQQ---WLLKIGNE 686
E + + +++ KS+ + +L G + + + S S L A+ Q+ L + E
Sbjct: 1305 EKEALINQLSREKSNFTRQIEDLRGQLEK--ETKSQSAL-AHALQKAQRDCDLLREQYEE 1361
Query: 687 INNGNIELQHHMDELHISMIQWMV---NLLILMIPNFTDQDCLLKLE-EESAEKHDIGVA 742
EL + +++ M+QW + N +I + D L + +E+AE + A
Sbjct: 1362 EQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANA 1421
Query: 743 R------------LEL-DAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDL 789
R LEL DA+ K+ ++ L K + + AL+ H+ + L
Sbjct: 1422 RNASLERARHQLQLELGDALSDLGKVRSAAARLDQ--KQLQSGKALADWKQKHEESQALL 1479
Query: 790 ----YEVDKLKKECYEWINT---------------------CSCLLSNIKGRKITLLTYE 824
EV L E + NT S L + ++ L E
Sbjct: 1480 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539
Query: 825 EIERLLEEEAVKEFIEPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRF 884
++++L+EEE K ++ ++E+ E + Q E E E +EK++
Sbjct: 1540 KVKKLIEEE--KTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDE---- 1593
Query: 885 IGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEE 944
E EN K D L S +S A+ +E + + M+E L E+E + A
Sbjct: 1594 --EIENFRRKQQCTIDSLQSSLDSE-----AKSRIEVTRLKKKMEEDLNEMELQLSCANR 1646
Query: 945 KFEDAYEKLHHTLIKNKDLEELVMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAENS 1004
+ +A + L I+ KDL+ + S + + + KE E + Q E E++RS +
Sbjct: 1647 QVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQ 1706
Query: 1005 SKSPKK 1010
++ ++
Sbjct: 1707 TERGRR 1712
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,361,783
Number of Sequences: 37866
Number of extensions: 1780377
Number of successful extensions: 33161
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 391
Number of HSP's successfully gapped in prelim test: 926
Number of HSP's that attempted gapping in prelim test: 13292
Number of HSP's gapped (non-prelim): 10213
length of query: 1012
length of database: 18,247,518
effective HSP length: 112
effective length of query: 900
effective length of database: 14,006,526
effective search space: 12605873400
effective search space used: 12605873400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.