Search of human proteins with 49574502

Search of human proteins with 49574502

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|49574502 cytochrome b5 reductase 1 [Homo sapiens]
         (305 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|49574502 cytochrome b5 reductase 1 [Homo sapiens]                  623   e-179
gi|4503327 cytochrome b5 reductase 3 isoform m [Homo sapiens]         375   e-104
gi|193794826 cytochrome b5 reductase 3 isoform s [Homo sapiens]       375   e-104
gi|6552328 cytochrome b5 reductase 3 isoform s [Homo sapiens]         375   e-104
gi|47778923 cytochrome b5 reductase b5R.2 [Homo sapiens]              354   6e-98
gi|84875541 cytochrome b5 reductase 4 [Homo sapiens]                  107   2e-23
gi|134133308 cytochrome b5 reductase-like [Homo sapiens]               88   1e-17
gi|19923907 oxidoreductase NAD-binding domain containing 1 [Homo...    40   0.003
gi|239757944 PREDICTED: hypothetical protein [Homo sapiens]            30   2.0  
gi|45439346 peptidylprolyl isomerase (cyclophilin)-like 5 isofor...    30   2.0  
gi|45439342 peptidylprolyl isomerase (cyclophilin)-like 5 isofor...    30   2.0  
gi|23957698 luman-recruiting factor [Homo sapiens]                     30   2.7  
gi|38569398 integrin, alpha 10 precursor [Homo sapiens]                29   4.5  
gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide ...    28   7.7  

>gi|49574502 cytochrome b5 reductase 1 [Homo sapiens]
          Length = 305

 Score =  623 bits (1606), Expect = e-179
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 1   MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHN 60
           MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHN
Sbjct: 1   MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHN 60

Query: 61  TKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKG 120
           TKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKG
Sbjct: 61  TKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKG 120

Query: 121 VHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLG 180
           VHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLG
Sbjct: 121 VHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLG 180

Query: 181 MIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW 240
           MIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW
Sbjct: 181 MIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW 240

Query: 241 FTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQK 300
           FTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQK
Sbjct: 241 FTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQK 300

Query: 301 MRFTY 305
           MRFTY
Sbjct: 301 MRFTY 305


>gi|4503327 cytochrome b5 reductase 3 isoform m [Homo sapiens]
          Length = 301

 Score =  375 bits (963), Expect = e-104
 Identities = 173/270 (64%), Positives = 218/270 (80%)

Query: 36  PQVTLLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVI 95
           P +TL  P+ KY LRL+D+  +SH+T+RFRFALP+  H LGLPVG+HIYLS RIDG+LV+
Sbjct: 32  PAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVV 91

Query: 96  RPYTPVTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTY 155
           RPYTP++SD+D+G+VDLVIKVY K  HPKFP GGKMSQYL+S+++GD +EFRGPSGLL Y
Sbjct: 92  RPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVY 151

Query: 156 TGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQ 215
            GKG F I+P+KKS P  R  K +GMIAGGTGITPMLQ+IRAI+K P+D T C LLFANQ
Sbjct: 152 QGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQ 211

Query: 216 TEKDIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLV 275
           TEKDI+LR +LEEL+ ++  RFKLW+TLD  P+ W Y +GFV  +MIR+HLP P ++ LV
Sbjct: 212 TEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLV 271

Query: 276 LLCGPPPMVQLACHPNLDKLGYSQKMRFTY 305
           L+CGPPPM+Q AC PNLD +G+  +  F +
Sbjct: 272 LMCGPPPMIQYACLPNLDHVGHPTERCFVF 301


>gi|193794826 cytochrome b5 reductase 3 isoform s [Homo sapiens]
          Length = 278

 Score =  375 bits (963), Expect = e-104
 Identities = 173/270 (64%), Positives = 218/270 (80%)

Query: 36  PQVTLLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVI 95
           P +TL  P+ KY LRL+D+  +SH+T+RFRFALP+  H LGLPVG+HIYLS RIDG+LV+
Sbjct: 9   PAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVV 68

Query: 96  RPYTPVTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTY 155
           RPYTP++SD+D+G+VDLVIKVY K  HPKFP GGKMSQYL+S+++GD +EFRGPSGLL Y
Sbjct: 69  RPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVY 128

Query: 156 TGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQ 215
            GKG F I+P+KKS P  R  K +GMIAGGTGITPMLQ+IRAI+K P+D T C LLFANQ
Sbjct: 129 QGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQ 188

Query: 216 TEKDIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLV 275
           TEKDI+LR +LEEL+ ++  RFKLW+TLD  P+ W Y +GFV  +MIR+HLP P ++ LV
Sbjct: 189 TEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLV 248

Query: 276 LLCGPPPMVQLACHPNLDKLGYSQKMRFTY 305
           L+CGPPPM+Q AC PNLD +G+  +  F +
Sbjct: 249 LMCGPPPMIQYACLPNLDHVGHPTERCFVF 278


>gi|6552328 cytochrome b5 reductase 3 isoform s [Homo sapiens]
          Length = 278

 Score =  375 bits (963), Expect = e-104
 Identities = 173/270 (64%), Positives = 218/270 (80%)

Query: 36  PQVTLLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVI 95
           P +TL  P+ KY LRL+D+  +SH+T+RFRFALP+  H LGLPVG+HIYLS RIDG+LV+
Sbjct: 9   PAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVV 68

Query: 96  RPYTPVTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTY 155
           RPYTP++SD+D+G+VDLVIKVY K  HPKFP GGKMSQYL+S+++GD +EFRGPSGLL Y
Sbjct: 69  RPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVY 128

Query: 156 TGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQ 215
            GKG F I+P+KKS P  R  K +GMIAGGTGITPMLQ+IRAI+K P+D T C LLFANQ
Sbjct: 129 QGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQ 188

Query: 216 TEKDIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLV 275
           TEKDI+LR +LEEL+ ++  RFKLW+TLD  P+ W Y +GFV  +MIR+HLP P ++ LV
Sbjct: 189 TEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLV 248

Query: 276 LLCGPPPMVQLACHPNLDKLGYSQKMRFTY 305
           L+CGPPPM+Q AC PNLD +G+  +  F +
Sbjct: 249 LMCGPPPMIQYACLPNLDHVGHPTERCFVF 278


>gi|47778923 cytochrome b5 reductase b5R.2 [Homo sapiens]
          Length = 276

 Score =  354 bits (908), Expect = 6e-98
 Identities = 160/272 (58%), Positives = 210/272 (77%)

Query: 34  RRPQVTLLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSL 93
           RR  +TL DP  KY L L++K  +SHNT+RFRF LP+  H LGLPVG ++ L  +ID  L
Sbjct: 5   RREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNEL 64

Query: 94  VIRPYTPVTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLL 153
           V+R YTPV+SD+D+G+VDL+IK+Y K VHP++PEGGKM+QYL+++K+G+ + FRGP G L
Sbjct: 65  VVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGRL 124

Query: 154 TYTGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFA 213
            Y G G+  I+P++ S P+  +A  LGMIAGGTGITPMLQLIR I K P D T+  L+FA
Sbjct: 125 FYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSLIFA 184

Query: 214 NQTEKDIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDV 273
           NQTE+DI++R++LEE+   +P++F LW+TLD PP  W YS GFVTADMI+EHLP P    
Sbjct: 185 NQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPPAKST 244

Query: 274 LVLLCGPPPMVQLACHPNLDKLGYSQKMRFTY 305
           L+L+CGPPP++Q A HPNL+KLGY+Q M FTY
Sbjct: 245 LILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY 276


>gi|84875541 cytochrome b5 reductase 4 [Homo sapiens]
          Length = 521

 Score =  107 bits (266), Expect = 2e-23
 Identities = 77/248 (31%), Positives = 123/248 (49%), Gaps = 38/248 (15%)

Query: 50  RLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSD----- 104
           +L+ K  V+H+T+ F   LP + H L +P+G+H+YL   I G+ +++PYTPV+       
Sbjct: 279 QLISKEDVTHDTRLFCLMLPPSTH-LQVPIGQHVYLKLPITGTEIVKPYTPVSGSLLSEF 337

Query: 105 -----EDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKG 159
                 +  Y+  +IK+Y  G+    PE       LD L++GD V    P        +G
Sbjct: 338 KEPVLPNNKYIYFLIKIYPTGLFT--PE-------LDRLQIGDFVSVSSP--------EG 380

Query: 160 HFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKD 219
           +F I   ++        + L ++A GTG TPM++++   L       +  L+F N+TE D
Sbjct: 381 NFKISKFQE-------LEDLFLLAAGTGFTPMVKILNYALTDIPSLRKVKLMFFNKTEDD 433

Query: 220 IILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGD--DVLVLL 277
           II R  LE+L A    R  + F L  P  +W   +G ++  ++ E L    D   VLV +
Sbjct: 434 IIWRSQLEKL-AFKDKRLDVEFVLSAPISEWNGKQGHISPALLSEFLKRNLDKSKVLVCI 492

Query: 278 CGPPPMVQ 285
           CGP P  +
Sbjct: 493 CGPVPFTE 500


>gi|134133308 cytochrome b5 reductase-like [Homo sapiens]
          Length = 315

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 70/247 (28%), Positives = 118/247 (47%), Gaps = 36/247 (14%)

Query: 41  LDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTP 100
           L+P       ++    ++ +T R RFALP  +  LGL  G+H+ L   +D   + R YTP
Sbjct: 72  LNPETFVAFCIIAMDRLTKDTYRVRFALP-GNSQLGLRPGQHLILRGIVDDLEIQRAYTP 130

Query: 101 VTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGH 160
           ++    +GY +++IK Y  G+         MS+Y++S +VGD   +RGP G   Y     
Sbjct: 131 ISPANAEGYFEVLIKCYQMGL---------MSRYVESWRVGDTAFWRGPFGDFFY----- 176

Query: 161 FNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDI 220
                      +P    +L ++A GTG+ PM+ ++++I     D T   L+   +T + I
Sbjct: 177 -----------KPNQYGELLLLAAGTGLAPMVPILQSITDNENDETFVTLVGCFKTFESI 225

Query: 221 ILREDLEELQARYPNRFKLWFTLDHPPKD----WAYSK----GFVTADMIREHLPAPGDD 272
            L+  L+E QAR+ N  + +F L          W+Y +    G +  D+I+E +      
Sbjct: 226 YLKTFLQE-QARFWN-VRTFFVLSQESSSEQLPWSYQEKTHFGHLGQDLIKELVSCCRRK 283

Query: 273 VLVLLCG 279
              L+CG
Sbjct: 284 PFALVCG 290


>gi|19923907 oxidoreductase NAD-binding domain containing 1 [Homo
           sapiens]
          Length = 312

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 21/130 (16%)

Query: 171 PEPRVAKK-LGMIAGGTGITPMLQLIRAILKVPEDPTQ---------CFLLFANQTEKDI 220
           P+P  A + L +IAGG GI P+L ++R    +  +              L ++ +   ++
Sbjct: 163 PQPADASRNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSEL 222

Query: 221 ILREDLEELQARYPNRF-------KLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDV 273
           + ++++ +L   +P +        K    ++   K +  ++G +T   IR+H+     + 
Sbjct: 223 LFKKNILDLVNEFPEKIACSLHVTKQTTQINAELKPY-ITEGRITEKEIRDHI---SKET 278

Query: 274 LVLLCGPPPM 283
           L  +CGPPPM
Sbjct: 279 LFYICGPPPM 288


>gi|239757944 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 600

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 17/48 (35%), Positives = 22/48 (45%)

Query: 250 WAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGY 297
           WA     + A ++          V VLL  P P+VQLAC P L   G+
Sbjct: 28  WAAYLALLLAGVVARQQALDVQAVAVLLITPQPLVQLACPPALALPGF 75


>gi|45439346 peptidylprolyl isomerase (cyclophilin)-like 5 isoform 3
           [Homo sapiens]
          Length = 146

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 179 LGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKD---IILREDLEELQARYPN 235
           LG+   G G+  +L L +   +  + P + FLL +   +K      LRE++E+   ++ +
Sbjct: 17  LGLRNRGKGVRAVLSLCQQTSR-SQPPVRAFLLISTLKDKRGTRYELRENIEQFFTKFVD 75

Query: 236 RFKLWFTLDHPPKDWAYSK 254
             K    L  PP D   SK
Sbjct: 76  EGKATVRLKEPPVDICLSK 94


>gi|45439342 peptidylprolyl isomerase (cyclophilin)-like 5 isoform 1
           [Homo sapiens]
          Length = 414

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 179 LGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKD---IILREDLEELQARYPN 235
           LG+   G G+  +L L +   +  + P + FLL +   +K      LRE++E+   ++ +
Sbjct: 17  LGLRNRGKGVRAVLSLCQQTSR-SQPPVRAFLLISTLKDKRGTRYELRENIEQFFTKFVD 75

Query: 236 RFKLWFTLDHPPKDWAYSK 254
             K    L  PP D   SK
Sbjct: 76  EGKATVRLKEPPVDICLSK 94


>gi|23957698 luman-recruiting factor [Homo sapiens]
          Length = 639

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 15/30 (50%), Positives = 19/30 (63%)

Query: 22  GLAVGSYLVRRSRRPQVTLLDPNEKYLLRL 51
           GL  G Y V++SRR  V  L PN K LL++
Sbjct: 469 GLHHGKYAVKKSRRTDVEDLTPNPKKLLQI 498


>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
          Length = 1167

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 7/59 (11%)

Query: 7   PVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTL-------LDPNEKYLLRLLDKTTVS 58
           P  L +   G VT  G+AV  + +RR R P   L        DP+E++   + D+  ++
Sbjct: 286 PAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALT 344


>gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide 1
           [Homo sapiens]
          Length = 509

 Score = 28.5 bits (62), Expect = 7.7
 Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 2/48 (4%)

Query: 193 QLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW 240
           +L+R +   P  PT  FL      + D +  E LEE+  +YP  F  W
Sbjct: 38  RLLRDLRPFPAPPTHWFLGHQKFIQDDNM--EKLEEIIEKYPRAFPFW 83


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.141    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,319,620
Number of Sequences: 37866
Number of extensions: 658340
Number of successful extensions: 1351
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1335
Number of HSP's gapped (non-prelim): 14
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.