Search of human proteins with 48762718

Search of human proteins with 48762718

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]
         (533 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]            1085   0.0  
gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]            1021   0.0  
gi|48762724 phosphodiesterase 9A isoform e [Homo sapiens]            1013   0.0  
gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens]             993   0.0  
gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens]             987   0.0  
gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens]              970   0.0  
gi|48762720 phosphodiesterase 9A isoform c [Homo sapiens]             941   0.0  
gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens]             915   0.0  
gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens]             914   0.0  
gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens]             914   0.0  
gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens]             904   0.0  
gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens]             885   0.0  
gi|48762722 phosphodiesterase 9A isoform d [Homo sapiens]             882   0.0  
gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762728 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens]             785   0.0  
gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens]             785   0.0  
gi|82799482 phosphodiesterase 4B isoform 2 [Homo sapiens]             178   1e-44
gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]            177   2e-44
gi|32306513 phosphodiesterase 4D isoform 2 [Homo sapiens]             177   2e-44
gi|82799486 phosphodiesterase 4B isoform 1 [Homo sapiens]             177   2e-44
gi|82799484 phosphodiesterase 4B isoform 3 [Homo sapiens]             177   2e-44
gi|32171241 phosphodiesterase 4B isoform 1 [Homo sapiens]             177   2e-44
gi|162329612 phosphodiesterase 4A isoform 3 [Homo sapiens]            177   3e-44
gi|162329610 phosphodiesterase 4A isoform 2 [Homo sapiens]            177   3e-44
gi|162329608 phosphodiesterase 4A isoform 1 [Homo sapiens]            177   3e-44
gi|5453862 phosphodiesterase 4A isoform 4 [Homo sapiens]              177   3e-44

>gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]
          Length = 533

 Score = 1085 bits (2806), Expect = 0.0
 Identities = 533/533 (100%), Positives = 533/533 (100%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60

Query: 61  VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH 120
           VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
Sbjct: 61  VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH 120

Query: 121 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 180
           LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
Sbjct: 121 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 180

Query: 181 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 240
           PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
Sbjct: 181 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 240

Query: 241 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 300
           CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
Sbjct: 241 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 300

Query: 301 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 360
           NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
Sbjct: 301 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 360

Query: 361 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 420
           LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
Sbjct: 361 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 420

Query: 421 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 480
           LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
Sbjct: 421 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 480

Query: 481 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 533
           QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 481 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 533


>gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]
          Length = 507

 Score = 1021 bits (2640), Expect = 0.0
 Identities = 507/533 (95%), Positives = 507/533 (95%), Gaps = 26/533 (4%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR             
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR------------- 47

Query: 61  VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH 120
                        TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
Sbjct: 48  -------------TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH 94

Query: 121 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 180
           LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
Sbjct: 95  LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 154

Query: 181 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 240
           PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
Sbjct: 155 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 214

Query: 241 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 300
           CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
Sbjct: 215 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 274

Query: 301 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 360
           NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
Sbjct: 275 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 334

Query: 361 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 420
           LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
Sbjct: 335 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 394

Query: 421 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 480
           LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
Sbjct: 395 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 454

Query: 481 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 533
           QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 455 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 507


>gi|48762724 phosphodiesterase 9A isoform e [Homo sapiens]
          Length = 540

 Score = 1013 bits (2618), Expect = 0.0
 Identities = 504/542 (92%), Positives = 512/542 (94%), Gaps = 11/542 (2%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60

Query: 61  VSIDPTMPANSERTPYKVRPVAIKQL---------SEREELIQSVLAQVAEQFSRAFKIN 111
           VSIDPTMPANSER    +   +++ L         +  +  +QS      +   RAFKIN
Sbjct: 61  VSIDPTMPANSERNEL-ILYTSLRNLLFLPSKESWASHQHSVQSETCG-HQATLRAFKIN 118

Query: 112 ELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNH 171
           ELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNH
Sbjct: 119 ELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNH 178

Query: 172 KKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSIN 231
           KKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSIN
Sbjct: 179 KKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSIN 238

Query: 232 PVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC 291
           PVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC
Sbjct: 239 PVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC 298

Query: 292 HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ 351
           HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ
Sbjct: 299 HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ 358

Query: 352 IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPME 411
           IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPME
Sbjct: 359 IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPME 418

Query: 412 VAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKL 471
           VAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKL
Sbjct: 419 VAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKL 478

Query: 472 FPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGD 531
           FPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGD
Sbjct: 479 FPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGD 538

Query: 532 CA 533
           CA
Sbjct: 539 CA 540


>gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens]
          Length = 492

 Score =  993 bits (2566), Expect = 0.0
 Identities = 487/487 (100%), Positives = 487/487 (100%)

Query: 47  RNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSR 106
           RNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSR
Sbjct: 6   RNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSR 65

Query: 107 AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS 166
           AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS
Sbjct: 66  AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS 125

Query: 167 FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR 226
           FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR
Sbjct: 126 FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR 185

Query: 227 DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM 286
           DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM
Sbjct: 186 DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM 245

Query: 287 TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP 346
           TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP
Sbjct: 246 TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP 305

Query: 347 DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE 406
           DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE
Sbjct: 306 DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE 365

Query: 407 VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE 466
           VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE
Sbjct: 366 VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE 425

Query: 467 TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK 526
           TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK
Sbjct: 426 TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK 485

Query: 527 NSEGDCA 533
           NSEGDCA
Sbjct: 486 NSEGDCA 492


>gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens]
          Length = 567

 Score =  987 bits (2551), Expect = 0.0
 Identities = 498/567 (87%), Positives = 504/567 (88%), Gaps = 34/567 (5%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNT----TISLLTT 56
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR       +++   
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL 60

Query: 57  DDAMVSIDPTMPANSERTPYKVRPVAIKQLS----------------------------- 87
              +     T    S   P + R V   +                               
Sbjct: 61  SAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIP 120

Query: 88  -EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK 146
            EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
Sbjct: 121 PEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK 180

Query: 147 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW 206
           KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
Sbjct: 181 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW 240

Query: 207 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS 266
           EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
Sbjct: 241 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS 300

Query: 267 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC 326
           MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
Sbjct: 301 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC 360

Query: 327 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 386
           AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
Sbjct: 361 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN 420

Query: 387 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK 446
           EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
Sbjct: 421 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK 480

Query: 447 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 506
           VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
Sbjct: 481 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 540

Query: 507 TDSLTSGATEKSRERSRDVKNSEGDCA 533
           TDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 541 TDSLTSGATEKSRERSRDVKNSEGDCA 567


>gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens]
          Length = 593

 Score =  970 bits (2508), Expect = 0.0
 Identities = 498/593 (83%), Positives = 507/593 (85%), Gaps = 60/593 (10%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60

Query: 61  VSIDPTMPANSERTPYKVRPVAIKQLS---------------EREELIQSVLAQVAEQFS 105
           VSIDPTMPANSERTPYKVRPVAIKQLS               ER    + V+     +  
Sbjct: 61  VSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE 120

Query: 106 RAFK----------------------------INELKAEVANHLAVLEKRVELEG----- 132
            AF+                            I  + A+VA   +   K  EL+      
Sbjct: 121 GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH 180

Query: 133 LKVVE------------IEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 180
           L V+E            IEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
Sbjct: 181 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 240

Query: 181 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 240
           PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
Sbjct: 241 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 300

Query: 241 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 300
           CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
Sbjct: 301 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 360

Query: 301 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 360
           NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
Sbjct: 361 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 420

Query: 361 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 420
           LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
Sbjct: 421 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 480

Query: 421 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 480
           LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
Sbjct: 481 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 540

Query: 481 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 533
           QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 541 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 593


>gi|48762720 phosphodiesterase 9A isoform c [Homo sapiens]
          Length = 466

 Score =  941 bits (2432), Expect = 0.0
 Identities = 460/460 (100%), Positives = 460/460 (100%)

Query: 74  TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL 133
           TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL
Sbjct: 7   TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL 66

Query: 134 KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI 193
           KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI
Sbjct: 67  KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI 126

Query: 194 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN 253
           EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN
Sbjct: 127 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN 186

Query: 254 FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV 313
           FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV
Sbjct: 187 FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV 246

Query: 314 RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD 373
           RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD
Sbjct: 247 RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD 306

Query: 374 SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS 433
           SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS
Sbjct: 307 SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS 366

Query: 434 EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 493
           EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL
Sbjct: 367 EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 426

Query: 494 KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 533
           KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 427 KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 466


>gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens]
          Length = 459

 Score =  915 bits (2365), Expect = 0.0
 Identities = 454/487 (93%), Positives = 454/487 (93%), Gaps = 33/487 (6%)

Query: 47  RNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSR 106
           RNTTISLLTTDDAMVSIDPTMPANSER                                 
Sbjct: 6   RNTTISLLTTDDAMVSIDPTMPANSER--------------------------------- 32

Query: 107 AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS 166
           AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS
Sbjct: 33  AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS 92

Query: 167 FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR 226
           FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR
Sbjct: 93  FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR 152

Query: 227 DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM 286
           DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM
Sbjct: 153 DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM 212

Query: 287 TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP 346
           TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP
Sbjct: 213 TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP 272

Query: 347 DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE 406
           DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE
Sbjct: 273 DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE 332

Query: 407 VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE 466
           VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE
Sbjct: 333 VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE 392

Query: 467 TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK 526
           TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK
Sbjct: 393 TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK 452

Query: 527 NSEGDCA 533
           NSEGDCA
Sbjct: 453 NSEGDCA 459


>gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens]
          Length = 552

 Score =  914 bits (2362), Expect = 0.0
 Identities = 446/446 (100%), Positives = 446/446 (100%)

Query: 88  EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK 147
           EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK
Sbjct: 107 EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK 166

Query: 148 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 207
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 167 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 226

Query: 208 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 267
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 227 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 286

Query: 268 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 327
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 287 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 346

Query: 328 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 387
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 347 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 406

Query: 388 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 447
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 407 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 466

Query: 448 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 507
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 467 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 526

Query: 508 DSLTSGATEKSRERSRDVKNSEGDCA 533
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 527 DSLTSGATEKSRERSRDVKNSEGDCA 552


>gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens]
          Length = 526

 Score =  914 bits (2362), Expect = 0.0
 Identities = 446/446 (100%), Positives = 446/446 (100%)

Query: 88  EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK 147
           EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK
Sbjct: 81  EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK 140

Query: 148 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 207
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 141 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 200

Query: 208 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 267
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 201 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 260

Query: 268 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 327
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 261 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 320

Query: 328 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 387
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 321 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 380

Query: 388 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 447
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 381 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 440

Query: 448 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 507
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 441 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 500

Query: 508 DSLTSGATEKSRERSRDVKNSEGDCA 533
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 501 DSLTSGATEKSRERSRDVKNSEGDCA 526


>gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens]
          Length = 491

 Score =  904 bits (2337), Expect = 0.0
 Identities = 459/533 (86%), Positives = 465/533 (87%), Gaps = 42/533 (7%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
           MGSGSSSYRPKAIYLDIDGRIQK                                     
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKE------------------------------------ 24

Query: 61  VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH 120
                 +PA+  R     RP   ++   R   +QS      +   RAFKINELKAEVANH
Sbjct: 25  ---HDHLPADHRRRHGLHRPHHAREF--RTHSVQSETCG-HQATLRAFKINELKAEVANH 78

Query: 121 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 180
           LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
Sbjct: 79  LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 138

Query: 181 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 240
           PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
Sbjct: 139 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 198

Query: 241 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 300
           CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
Sbjct: 199 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 258

Query: 301 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 360
           NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
Sbjct: 259 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 318

Query: 361 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 420
           LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
Sbjct: 319 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 378

Query: 421 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 480
           LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
Sbjct: 379 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 438

Query: 481 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 533
           QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 439 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 491


>gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens]
          Length = 433

 Score =  885 bits (2286), Expect = 0.0
 Identities = 429/432 (99%), Positives = 430/432 (99%)

Query: 102 EQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC 161
           + F RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC
Sbjct: 2   DAFRRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC 61

Query: 162 PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD 221
           PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD
Sbjct: 62  PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD 121

Query: 222 LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD 281
           LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD
Sbjct: 122 LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD 181

Query: 282 ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF 341
           ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF
Sbjct: 182 ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF 241

Query: 342 SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC 401
           SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC
Sbjct: 242 SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC 301

Query: 402 DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL 461
           DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL
Sbjct: 302 DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL 361

Query: 462 IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER 521
           IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER
Sbjct: 362 IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER 421

Query: 522 SRDVKNSEGDCA 533
           SRDVKNSEGDCA
Sbjct: 422 SRDVKNSEGDCA 433


>gi|48762722 phosphodiesterase 9A isoform d [Homo sapiens]
          Length = 465

 Score =  882 bits (2280), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 106 RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 165
           RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY
Sbjct: 38  RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 97

Query: 166 SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 225
           SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV
Sbjct: 98  SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 157

Query: 226 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 285
           RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL
Sbjct: 158 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 217

Query: 286 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 345
           MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP
Sbjct: 218 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 277

Query: 346 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 405
           PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN
Sbjct: 278 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 337

Query: 406 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 465
           EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF
Sbjct: 338 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 397

Query: 466 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 525
           ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV
Sbjct: 398 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 457

Query: 526 KNSEGDCA 533
           KNSEGDCA
Sbjct: 458 KNSEGDCA 465



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 23/23 (100%), Positives = 23/23 (100%)

Query: 1  MGSGSSSYRPKAIYLDIDGRIQK 23
          MGSGSSSYRPKAIYLDIDGRIQK
Sbjct: 1  MGSGSSSYRPKAIYLDIDGRIQK 23


>gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 148 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 207
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 208 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 267
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 268 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 327
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 328 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 387
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 388 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 447
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 448 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 507
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 508 DSLTSGATEKSRERSRDVKNSEGDCA 533
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 148 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 207
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 208 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 267
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 268 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 327
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 328 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 387
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 388 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 447
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 448 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 507
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 508 DSLTSGATEKSRERSRDVKNSEGDCA 533
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 148 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 207
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 208 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 267
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 268 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 327
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 328 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 387
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 388 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 447
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 448 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 507
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 508 DSLTSGATEKSRERSRDVKNSEGDCA 533
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 148 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 207
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 208 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 267
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 268 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 327
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 328 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 387
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 388 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 447
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 448 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 507
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 508 DSLTSGATEKSRERSRDVKNSEGDCA 533
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762728 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 148 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 207
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 208 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 267
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 268 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 327
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 328 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 387
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 388 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 447
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 448 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 507
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 508 DSLTSGATEKSRERSRDVKNSEGDCA 533
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens]
          Length = 376

 Score =  785 bits (2026), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 159 TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 218
           TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM
Sbjct: 2   TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 61

Query: 219 YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 278
           YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS
Sbjct: 62  YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 121

Query: 279 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 338
           QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC
Sbjct: 122 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 181

Query: 339 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 398
           NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI
Sbjct: 182 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 241

Query: 399 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 458
           KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK
Sbjct: 242 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 301

Query: 459 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 518
           FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS
Sbjct: 302 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 361

Query: 519 RERSRDVKNSEGDCA 533
           RERSRDVKNSEGDCA
Sbjct: 362 RERSRDVKNSEGDCA 376


>gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens]
          Length = 376

 Score =  785 bits (2026), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 159 TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 218
           TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM
Sbjct: 2   TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 61

Query: 219 YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 278
           YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS
Sbjct: 62  YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 121

Query: 279 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 338
           QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC
Sbjct: 122 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 181

Query: 339 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 398
           NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI
Sbjct: 182 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 241

Query: 399 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 458
           KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK
Sbjct: 242 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 301

Query: 459 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 518
           FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS
Sbjct: 302 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 361

Query: 519 RERSRDVKNSEGDCA 533
           RERSRDVKNSEGDCA
Sbjct: 362 RERSRDVKNSEGDCA 376


>gi|82799482 phosphodiesterase 4B isoform 2 [Homo sapiens]
          Length = 564

 Score =  178 bits (452), Expect = 1e-44
 Identities = 143/517 (27%), Positives = 257/517 (49%), Gaps = 41/517 (7%)

Query: 48  NTTISLLTTDDAMVSIDPTMPAN------SERTPYKVRPVAIKQLS---EREELIQSVLA 98
           +T IS  + D AM S+ P  P        +E +  K+    +++L    ++ E IQ+  +
Sbjct: 10  STGISGGSGDSAMDSLQPLQPNYMPVCLFAEESYQKLAMETLEELDWCLDQLETIQTYRS 69

Query: 99  QVAEQFSRAFK---------INELKAEVANHLAVLEKRVELEGLKVVEIEKC--KSDIKK 147
            V+E  S  FK         ++E+     N ++       L+    VEI     K   KK
Sbjct: 70  -VSEMASNKFKRMLNRELTHLSEMSRS-GNQVSEYISNTFLDKQNDVEIPSPTQKDREKK 127

Query: 148 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRK---PTFDVW 204
            +++L  + S        S L+N      R  V T  +  L+ E +E L K     F+V 
Sbjct: 128 KKQQLMTQISGVKKLMHSSSLNNTS--ISRFGVNTENEDHLAKE-LEDLNKWGLNIFNVA 184

Query: 205 LWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQ 262
            +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H   VAQ
Sbjct: 185 GYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQ 244

Query: 263 MMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLE 322
             + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND S LE
Sbjct: 245 STHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE 304

Query: 323 NHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENF 382
           NHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  +E  
Sbjct: 305 NHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETK 364

Query: 383 DYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSE 434
             ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+E+  
Sbjct: 365 KVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERER 424

Query: 435 GLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELK 494
           G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y+ + 
Sbjct: 425 GMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM- 483

Query: 495 RIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 530
            I  +      + +    G  EK + E + D ++SEG
Sbjct: 484 -IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 519


>gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]
          Length = 809

 Score =  177 bits (449), Expect = 2e-44
 Identities = 98/328 (29%), Positives = 176/328 (53%), Gaps = 20/328 (6%)

Query: 184 PKYLLSPETIEALRKPTFDVWLW----------EPNEMLSCLEH-MYHDLGLVRDFSINP 232
           P++ +  E  + L K   DV  W            N  L+ + H ++ +  L++ F I  
Sbjct: 382 PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPV 441

Query: 233 VTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC 291
            TL  +L  + D+Y  +  +HN  H   V Q  + ++   +L+  F+  +IL  + A+  
Sbjct: 442 DTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAI 501

Query: 292 HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ 351
           HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     + 
Sbjct: 502 HDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQS 561

Query: 352 IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCDI 403
           +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D+
Sbjct: 562 LRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL 621

Query: 404 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP 463
           SN  +P+++   W D ++EE+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ P
Sbjct: 622 SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHP 681

Query: 464 MFETVTKLFPMVEEIMLQPLWESRDRYE 491
           ++ET   L     + +L  L ++R+ Y+
Sbjct: 682 LWETWADLVHPDAQDILDTLEDNREWYQ 709


>gi|32306513 phosphodiesterase 4D isoform 2 [Homo sapiens]
          Length = 673

 Score =  177 bits (449), Expect = 2e-44
 Identities = 98/328 (29%), Positives = 176/328 (53%), Gaps = 20/328 (6%)

Query: 184 PKYLLSPETIEALRKPTFDVWLW----------EPNEMLSCLEH-MYHDLGLVRDFSINP 232
           P++ +  E  + L K   DV  W            N  L+ + H ++ +  L++ F I  
Sbjct: 246 PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPV 305

Query: 233 VTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC 291
            TL  +L  + D+Y  +  +HN  H   V Q  + ++   +L+  F+  +IL  + A+  
Sbjct: 306 DTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAI 365

Query: 292 HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ 351
           HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     + 
Sbjct: 366 HDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQS 425

Query: 352 IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCDI 403
           +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D+
Sbjct: 426 LRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL 485

Query: 404 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP 463
           SN  +P+++   W D ++EE+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ P
Sbjct: 486 SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHP 545

Query: 464 MFETVTKLFPMVEEIMLQPLWESRDRYE 491
           ++ET   L     + +L  L ++R+ Y+
Sbjct: 546 LWETWADLVHPDAQDILDTLEDNREWYQ 573


>gi|82799486 phosphodiesterase 4B isoform 1 [Homo sapiens]
          Length = 736

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 201 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 258
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 353 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 412

Query: 259 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 318
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 413 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 472

Query: 319 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 378
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 473 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 532

Query: 379 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 430
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 533 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 592

Query: 431 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 490
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 593 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 652

Query: 491 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 530
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 653 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 691


>gi|82799484 phosphodiesterase 4B isoform 3 [Homo sapiens]
          Length = 721

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 201 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 258
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 338 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 397

Query: 259 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 318
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 398 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 457

Query: 319 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 378
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 458 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 517

Query: 379 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 430
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 518 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 577

Query: 431 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 490
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 578 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 637

Query: 491 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 530
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 638 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 676


>gi|32171241 phosphodiesterase 4B isoform 1 [Homo sapiens]
          Length = 736

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 201 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 258
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 353 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 412

Query: 259 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 318
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 413 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 472

Query: 319 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 378
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 473 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 532

Query: 379 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 430
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 533 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 592

Query: 431 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 490
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 593 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 652

Query: 491 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 530
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 653 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 691


>gi|162329612 phosphodiesterase 4A isoform 3 [Homo sapiens]
          Length = 825

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 176 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 231
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 292 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 350

Query: 232 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 290
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 351 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 410

Query: 291 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 350
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 411 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 470

Query: 351 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 402
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 471 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 530

Query: 403 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 462
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 531 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 590

Query: 463 PMFETVTKLFPMVEEIMLQPLWESRDRY 490
           P++ET   L     + +L  L ++RD Y
Sbjct: 591 PLWETWADLVHPDAQEILDTLEDNRDWY 618


>gi|162329610 phosphodiesterase 4A isoform 2 [Homo sapiens]
          Length = 860

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 176 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 231
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 327 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 385

Query: 232 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 290
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 386 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 445

Query: 291 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 350
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 446 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 505

Query: 351 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 402
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 506 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 565

Query: 403 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 462
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 566 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 625

Query: 463 PMFETVTKLFPMVEEIMLQPLWESRDRY 490
           P++ET   L     + +L  L ++RD Y
Sbjct: 626 PLWETWADLVHPDAQEILDTLEDNRDWY 653


>gi|162329608 phosphodiesterase 4A isoform 1 [Homo sapiens]
          Length = 886

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 176 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 231
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 353 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 411

Query: 232 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 290
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 412 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 471

Query: 291 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 350
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 472 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 531

Query: 351 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 402
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 532 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 591

Query: 403 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 462
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 592 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 651

Query: 463 PMFETVTKLFPMVEEIMLQPLWESRDRY 490
           P++ET   L     + +L  L ++RD Y
Sbjct: 652 PLWETWADLVHPDAQEILDTLEDNRDWY 679


>gi|5453862 phosphodiesterase 4A isoform 4 [Homo sapiens]
          Length = 647

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 176 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 231
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 114 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 172

Query: 232 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 290
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 173 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 232

Query: 291 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 350
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 233 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 292

Query: 351 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 402
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 293 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 352

Query: 403 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 462
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 353 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 412

Query: 463 PMFETVTKLFPMVEEIMLQPLWESRDRY 490
           P++ET   L     + +L  L ++RD Y
Sbjct: 413 PLWETWADLVHPDAQEILDTLEDNRDWY 440


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,260,371
Number of Sequences: 37866
Number of extensions: 815261
Number of successful extensions: 2863
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2640
Number of HSP's gapped (non-prelim): 155
length of query: 533
length of database: 18,247,518
effective HSP length: 107
effective length of query: 426
effective length of database: 14,195,856
effective search space: 6047434656
effective search space used: 6047434656
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.