Guide to the Human Genome
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Search of human proteins with 4826952

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826952 proteasome 26S non-ATPase subunit 5 [Homo sapiens]
         (504 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826952 proteasome 26S non-ATPase subunit 5 [Homo sapiens]         976   0.0  
gi|4504897 karyopherin alpha 2 [Homo sapiens]                          37   0.055
gi|156151430 armadillo repeat containing 9 [Homo sapiens]              32   1.0  
gi|4757956 cadherin 16 precursor [Homo sapiens]                        31   2.3  
gi|209969832 FAST kinase domains 2 [Homo sapiens]                      31   3.0  
gi|209969830 FAST kinase domains 2 [Homo sapiens]                      31   3.0  
gi|45267832 FAST kinase domains 2 [Homo sapiens]                       31   3.0  
gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]          31   3.0  
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]       30   3.9  
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]         30   3.9  
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]        30   3.9  
gi|82775371 coiled-coil domain containing 93 [Homo sapiens]            30   6.7  
gi|122937227 U2-associated SR140 protein [Homo sapiens]                29   8.8  

>gi|4826952 proteasome 26S non-ATPase subunit 5 [Homo sapiens]
          Length = 504

 Score =  976 bits (2524), Expect = 0.0
 Identities = 504/504 (100%), Positives = 504/504 (100%)

Query: 1   MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK 60
           MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
Sbjct: 1   MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK 60

Query: 61  TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI 120
           TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
Sbjct: 61  TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI 120

Query: 121 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI 180
           LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
Sbjct: 121 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI 180

Query: 181 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG 240
           VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
Sbjct: 181 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG 240

Query: 241 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV 300
           RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
Sbjct: 241 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV 300

Query: 301 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR 360
           FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
Sbjct: 301 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR 360

Query: 361 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA 420
           CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA
Sbjct: 361 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA 420

Query: 421 IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR 480
           IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR
Sbjct: 421 IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR 480

Query: 481 LRTYLSEGPYYVKPVSTTAVEGAE 504
           LRTYLSEGPYYVKPVSTTAVEGAE
Sbjct: 481 LRTYLSEGPYYVKPVSTTAVEGAE 504


>gi|4504897 karyopherin alpha 2 [Homo sapiens]
          Length = 529

 Score = 36.6 bits (83), Expect = 0.055
 Identities = 49/228 (21%), Positives = 88/228 (38%), Gaps = 22/228 (9%)

Query: 48  PLFSLLNENHREKTTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQI 107
           P  S L   +    T  +S L R      P+     +   L R L H D  V   T   I
Sbjct: 216 PDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI 275

Query: 108 GRIVENSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRI---------SLTQAG 158
             + +  +    ++    ++ Q+V  +G   L +   A++++  I          +  AG
Sbjct: 276 SYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAG 335

Query: 159 LEALFESNLLDDLKSVMKTNDIVRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTG 218
             A+F S L +      KTN  ++      +  I++   + +      GLV  L+  L+ 
Sbjct: 336 ALAVFPSLLTNP-----KTN--IQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSK 388

Query: 219 EDVLVRATCIEMVTSLAYTHHGR----QYLAQEGVIDQISNIIVGADS 262
            D   +   +  VT+  YT  G      YL   G+I+ + N++   D+
Sbjct: 389 ADFKTQKEAVWAVTN--YTSGGTVEQIVYLVHCGIIEPLMNLLTAKDT 434


>gi|156151430 armadillo repeat containing 9 [Homo sapiens]
          Length = 665

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 36/153 (23%), Positives = 70/153 (45%), Gaps = 14/153 (9%)

Query: 159 LEALFESNLLD----DLKSVMK----TNDIVRYRVYELIIEISSVSPESLNYCTTSGLVT 210
           L+A   ++LLD    + +SV++    T+D+VR  +  LI   +S++ E   Y   +  V 
Sbjct: 357 LQAYISNDLLDCYSHNQRSVLQLLHSTSDVVRQYMARLINAFASLA-EGRLYLAQNTKVL 415

Query: 211 QLLRELTGE---DVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSS 267
           Q+L     E   D++ R   +  +   +     +  + Q+G+I  + +++   D D  S 
Sbjct: 416 QMLEGRLKEEDKDIITRENVLGALQKFSLRRPLQTAMIQDGLIFWLVDVL--KDPDCLSD 473

Query: 268 FYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV 300
           + L   V    NL +  + + +C +    V KV
Sbjct: 474 YTLEYSVALLMNLCLRSTGKNMCAKVAGLVLKV 506


>gi|4757956 cadherin 16 precursor [Homo sapiens]
          Length = 829

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 13/30 (43%), Positives = 21/30 (70%)

Query: 57  HREKTTLCVSILERLLQAMEPVHVARNLRV 86
           H+   T+ VSI+E    ++EP+H+A NL+V
Sbjct: 223 HQATATVEVSIIESTWVSLEPIHLAENLKV 252


>gi|209969832 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 48/173 (27%)

Query: 22  LRALHSVLQ-AVPLNELRQQAAELRLGPLFSLLNENHREKTTLCVSILERLLQAMEP--- 77
           L +LH++++  +P N +  Q        L  +  E   E   +C+S+L  +L+AMEP   
Sbjct: 233 LFSLHAIVKLGIPQNTILVQT-------LLRVTQERINECDEICLSVLSTVLEAMEPCKN 285

Query: 78  VHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEILNNAELLKQIVYCIGGE 137
           VHV R                 +IL   Q+ +I    D  T        L+ ++ CIG +
Sbjct: 286 VHVLRT--------------GFRILVDQQVWKI---EDVFT--------LQVVMKCIGKD 320

Query: 138 -----NLSVAKAAIKSLSRISL--TQAGLEALFESN-----LLDDLKSVMKTN 178
                   +   A++ L R S+  +Q   E L   N     LLD+   V+  N
Sbjct: 321 APIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDN 373


>gi|209969830 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 48/173 (27%)

Query: 22  LRALHSVLQ-AVPLNELRQQAAELRLGPLFSLLNENHREKTTLCVSILERLLQAMEP--- 77
           L +LH++++  +P N +  Q        L  +  E   E   +C+S+L  +L+AMEP   
Sbjct: 233 LFSLHAIVKLGIPQNTILVQT-------LLRVTQERINECDEICLSVLSTVLEAMEPCKN 285

Query: 78  VHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEILNNAELLKQIVYCIGGE 137
           VHV R                 +IL   Q+ +I    D  T        L+ ++ CIG +
Sbjct: 286 VHVLRT--------------GFRILVDQQVWKI---EDVFT--------LQVVMKCIGKD 320

Query: 138 -----NLSVAKAAIKSLSRISL--TQAGLEALFESN-----LLDDLKSVMKTN 178
                   +   A++ L R S+  +Q   E L   N     LLD+   V+  N
Sbjct: 321 APIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDN 373


>gi|45267832 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 48/173 (27%)

Query: 22  LRALHSVLQ-AVPLNELRQQAAELRLGPLFSLLNENHREKTTLCVSILERLLQAMEP--- 77
           L +LH++++  +P N +  Q        L  +  E   E   +C+S+L  +L+AMEP   
Sbjct: 233 LFSLHAIVKLGIPQNTILVQT-------LLRVTQERINECDEICLSVLSTVLEAMEPCKN 285

Query: 78  VHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEILNNAELLKQIVYCIGGE 137
           VHV R                 +IL   Q+ +I    D  T        L+ ++ CIG +
Sbjct: 286 VHVLRT--------------GFRILVDQQVWKI---EDVFT--------LQVVMKCIGKD 320

Query: 138 -----NLSVAKAAIKSLSRISL--TQAGLEALFESN-----LLDDLKSVMKTN 178
                   +   A++ L R S+  +Q   E L   N     LLD+   V+  N
Sbjct: 321 APIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDN 373


>gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]
          Length = 766

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 24/88 (27%), Positives = 46/88 (52%), Gaps = 5/88 (5%)

Query: 1   MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK 60
           + ++A+ LL ++AR+E   + LRAL  V+ A+  ++  +         LF L N  +R +
Sbjct: 370 ITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVTGSAALFYLTNSEYRSE 429

Query: 61  TTLCV--SILERLLQAME---PVHVARN 83
            ++ +   +++ +L  ME    V V RN
Sbjct: 430 QSVKLRRQVIQVVLNGMESYQEVTVQRN 457


>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
          Length = 1439

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 42/183 (22%), Positives = 75/183 (40%), Gaps = 12/183 (6%)

Query: 52  LLNENHREKTTLCVSILERLLQAMEPVH---VARNLRVDLQRGLIHPDDSVKILTLSQIG 108
           L N + R+      S+ +      + VH   VA  L   ++ G    D + +   L  +G
Sbjct: 115 LYNSSGRDLRRALFSLKQIFQDDKDLVHEFVVAEGLTCLIKVGA-EADQNYQNYILRALG 173

Query: 109 RIVENSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIK-SLSRISLTQAGLEALFESNL 167
           +I+   D +  ++N  E ++ +   IG +   V K A+K  L  +  +++    L ++  
Sbjct: 174 QIMLYVDGMNGVINRNETIQWLYTLIGSKFRLVVKTALKLLLVFVEYSESNAPLLIQAVT 233

Query: 168 LDDLKSVMKTNDIVRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRAT- 226
             D K  +K        + E++ E   V  E L Y  T  LV + L  L  +D       
Sbjct: 234 AVDTKRGVKPWS----NIMEILEEKDGVDTELLVYAMT--LVNKTLSGLPDQDTFYDVVD 287

Query: 227 CIE 229
           C+E
Sbjct: 288 CLE 290


>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
          Length = 509

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 38/213 (17%), Positives = 90/213 (42%), Gaps = 5/213 (2%)

Query: 55  ENHREKTTLCVSILERLLQAMEPVHVARNLRVD--LQRGLIHPDDSVKILTLSQIGRIVE 112
           E +++  T  V ++  L    + +   +N  V   L+  L+    +++      +GR+  
Sbjct: 11  EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN 70

Query: 113 NSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGL-EALFESNLLDDL 171
            +D + E +   ++L Q+VY +  +N    KAA   L  +      L +A+ +   LD L
Sbjct: 71  YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTL 130

Query: 172 KSVMKTNDI-VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEM 230
              ++  D  V+      +  I+  + E       +G V  L+  +   ++ ++      
Sbjct: 131 VICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASA 190

Query: 231 VTSLA-YTHHGRQYLAQEGVIDQISNIIVGADS 262
           ++ +A ++    Q +   G +  ++ +I+  D+
Sbjct: 191 LSDIAKHSPELAQTVVDAGAVAHLAQMILNPDA 223


>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
          Length = 458

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 38/213 (17%), Positives = 90/213 (42%), Gaps = 5/213 (2%)

Query: 55  ENHREKTTLCVSILERLLQAMEPVHVARNLRVD--LQRGLIHPDDSVKILTLSQIGRIVE 112
           E +++  T  V ++  L    + +   +N  V   L+  L+    +++      +GR+  
Sbjct: 11  EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN 70

Query: 113 NSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGL-EALFESNLLDDL 171
            +D + E +   ++L Q+VY +  +N    KAA   L  +      L +A+ +   LD L
Sbjct: 71  YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTL 130

Query: 172 KSVMKTNDI-VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEM 230
              ++  D  V+      +  I+  + E       +G V  L+  +   ++ ++      
Sbjct: 131 VICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASA 190

Query: 231 VTSLA-YTHHGRQYLAQEGVIDQISNIIVGADS 262
           ++ +A ++    Q +   G +  ++ +I+  D+
Sbjct: 191 LSDIAKHSPELAQTVVDAGAVAHLAQMILNPDA 223


>gi|82775371 coiled-coil domain containing 93 [Homo sapiens]
          Length = 631

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 12/82 (14%)

Query: 4   QALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREKTTL 63
           + ++L +++A+    LEELRA H+ LQA   NE ++   EL+           + EK   
Sbjct: 318 KVISLNKQIAQKTKHLEELRASHTSLQA-RYNEAKKTLTELK----------TYSEKLDK 366

Query: 64  CVSILERLLQAMEPVHVARNLR 85
             + LE++    +P  + +NLR
Sbjct: 367 EQAALEKIESKADP-SILQNLR 387


>gi|122937227 U2-associated SR140 protein [Homo sapiens]
          Length = 1029

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 18/41 (43%), Positives = 27/41 (65%), Gaps = 2/41 (4%)

Query: 115 DAVTEILNNAELLKQIVYCIGGENLSVAKAAI-KSLSRISL 154
           DA+   LNNAE  ++IV CI  E+LS+ K  + K ++R+ L
Sbjct: 558 DAMVFCLNNAEAAEEIVDCI-TESLSILKTPLPKKIARLYL 597


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,639,615
Number of Sequences: 37866
Number of extensions: 663817
Number of successful extensions: 1590
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1580
Number of HSP's gapped (non-prelim): 19
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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