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Search of human proteins with 4758204
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
(367 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 731 0.0
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 456 e-128
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 361 e-100
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 309 2e-84
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 294 1e-79
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 179 3e-45
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 167 1e-41
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 166 3e-41
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 163 2e-40
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 159 4e-39
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 154 2e-37
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 114 2e-25
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 112 7e-25
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 112 7e-25
gi|37674210 slingshot 2 [Homo sapiens] 107 2e-23
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 102 4e-22
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 102 4e-22
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 102 4e-22
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 100 2e-21
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 95 9e-20
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 93 4e-19
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 89 5e-18
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 89 5e-18
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 89 5e-18
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 88 1e-17
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 88 1e-17
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 87 2e-17
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 84 3e-16
gi|239582767 slingshot homolog 3 [Homo sapiens] 82 6e-16
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 81 1e-15
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 731 bits (1886), Expect = 0.0
Identities = 367/367 (100%), Positives = 367/367 (100%)
Query: 1 MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM 60
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM
Sbjct: 1 MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM 60
Query: 61 GLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFF 120
GLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFF
Sbjct: 61 GLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFF 120
Query: 121 LKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPF 180
LKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPF
Sbjct: 121 LKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPF 180
Query: 181 LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA 240
LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA
Sbjct: 181 LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA 240
Query: 241 IDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS 300
IDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS
Sbjct: 241 IDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS 300
Query: 301 FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSP 360
FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSP
Sbjct: 301 FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSP 360
Query: 361 ITTSPSC 367
ITTSPSC
Sbjct: 361 ITTSPSC 367
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 456 bits (1172), Expect = e-128
Identities = 233/369 (63%), Positives = 275/369 (74%), Gaps = 7/369 (1%)
Query: 6 GTLDAGGLRALLG-ERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEH 64
G G LG +CLLLDCR F A +AG+I GSVNVR +TIVRRRAKG++ LE
Sbjct: 26 GGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQ 85
Query: 65 IVP-NAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKG 123
I+P E+R RL +G Y AV++ DERS + + D T++L AL R A + LKG
Sbjct: 86 ILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKG 145
Query: 124 GYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYL 183
GYE FS+ PE CSK + P+ S + + GCSSC TPL+DQGGPVEILPFLYL
Sbjct: 146 GYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYL 205
Query: 184 GSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDF 243
GSAYHA+R+DMLDALGITAL+NVS++CPNHFEGHYQYK IPVEDNHKADISSWF EAI++
Sbjct: 206 GSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEY 265
Query: 244 IDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMG 303
ID++K+ GRV VHCQAGISRSATICLAYLM RV+L+EAFEFVKQRRSIISPNFSFMG
Sbjct: 266 IDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMG 325
Query: 304 QLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTT-----VFNFPVSIPVHSTNSALSYLQ 358
QLLQFESQVLA C+AEA SP+ + +RG + T VF+FPVS+ VHS S+L YL
Sbjct: 326 QLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLH 385
Query: 359 SPITTSPSC 367
SPITTSPSC
Sbjct: 386 SPITTSPSC 394
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 361 bits (927), Expect = e-100
Identities = 182/271 (67%), Positives = 211/271 (77%), Gaps = 13/271 (4%)
Query: 102 LALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGC 161
LA + LC E++ GGYE FS+ PE CSK + P+ S + + GC
Sbjct: 41 LAGRSRCLCSESQ--------GGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGC 92
Query: 162 SSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYK 221
SSC TPL+DQGGPVEILPFLYLGSAYHA+R+DMLDALGITAL+NVS++CPNHFEGHYQYK
Sbjct: 93 SSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYK 152
Query: 222 SIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKL 281
IPVEDNHKADISSWF EAI++ID++K+ GRV VHCQAGISRSATICLAYLM RV+L
Sbjct: 153 CIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRL 212
Query: 282 DEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTT---- 337
+EAFEFVKQRRSIISPNFSFMGQLLQFESQVLA C+AEA SP+ + +RG + T
Sbjct: 213 EEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQ 272
Query: 338 -VFNFPVSIPVHSTNSALSYLQSPITTSPSC 367
VF+FPVS+ VHS S+L YL SPITTSPSC
Sbjct: 273 FVFSFPVSVGVHSAPSSLPYLHSPITTSPSC 303
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 309 bits (792), Expect = 2e-84
Identities = 167/312 (53%), Positives = 214/312 (68%), Gaps = 14/312 (4%)
Query: 8 LDAGGLRALLGE--RAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKG--AMGLE 63
L+ L LL + A + LLLDCR F AF H+ + V ++ ++RRRA+G A L
Sbjct: 9 LECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLA 68
Query: 64 HIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQ--VFFL 121
++P+ LR RL+ G V+LDE SA++ + D + AL E RA V+FL
Sbjct: 69 CLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFL 128
Query: 122 KGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFL 181
+GG++ F CP+LCS+ P +LP P ++ S P+YDQGGPVEILP+L
Sbjct: 129 RGGFDGFQGCCPDLCSEAPAP---ALP-----PTGDKTSRSDSRAPVYDQGGPVEILPYL 180
Query: 182 YLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAI 241
+LGS H+S L A GITA++NVSA+CPNHFEG ++YKSIPVEDN +IS+WF EAI
Sbjct: 181 FLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAI 240
Query: 242 DFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSF 301
FID +KN+GGRV VHCQAGISRSATICLAYLM++ RV+LDEAF+FVKQRR +ISPNFSF
Sbjct: 241 GFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSF 300
Query: 302 MGQLLQFESQVL 313
MGQLLQFE+QVL
Sbjct: 301 MGQLLQFETQVL 312
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 294 bits (752), Expect = 1e-79
Identities = 178/394 (45%), Positives = 237/394 (60%), Gaps = 39/394 (9%)
Query: 3 MEVGTLDAGGLRALLG-ERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKG-AM 60
M+V +LD LR +L E AA+C++LDCR + AF A ++ GS+NV +++V RRA+G A+
Sbjct: 1 MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV 60
Query: 61 GLEHIVPNAELRGRLL---AGAYHAVVLLDERSAALDGAKRDGTLALAAGAL--CREARA 115
+++P+ R RLL G AVV+LD+ S + + + +L C A
Sbjct: 61 SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPA-G 119
Query: 116 AQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPL------- 168
+V+FLKGGYE F + PE C P+S +S + S C P+
Sbjct: 120 PRVYFLKGGYETFYSEYPECCVDVK-------PISQEKIESERALISQCGKPVVNVSYRP 172
Query: 169 -YDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVED 227
YDQGGPVEILPFLYLGSAYHAS+ + L L ITAL+NVS H YK IPVED
Sbjct: 173 AYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVED 232
Query: 228 NHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEF 287
+H ADISS F EAIDFID ++ GG+V VHC+AGISRS TIC+AYLM+T + +L EAF++
Sbjct: 233 SHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292
Query: 288 VKQRRSIISPNFSFMGQLLQFESQVL-------APHCSAE-AGSPAMAVLD------RGT 333
+KQRRS++SPNF FMGQLLQ+ES++L P C E AGS + L +G
Sbjct: 293 IKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGA 352
Query: 334 STTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC 367
T + +P HST S LS +SP+ T+ SC
Sbjct: 353 YCTFPASVLAPVPTHSTVSELS--RSPVATATSC 384
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 179 bits (455), Expect = 3e-45
Identities = 119/329 (36%), Positives = 174/329 (52%), Gaps = 28/329 (8%)
Query: 22 AQCLLLDCRSFFAFNAGHIAGSVNVRF-STIVRRRAKGAMGLEHIVPNAELRGRLLAGAY 80
A LLLDCR F + HI ++N+ ++RR KG + + I+PN + R
Sbjct: 70 ASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCK 129
Query: 81 HAVVLLDERSAALDGAKRDGTLALAAGALCREAR--AAQVFFLKGGYEAFSASCPELC-- 136
A VLL + + A + G A G L ++ R Q ++L+GG+ F E C
Sbjct: 130 AATVLLYDEATA-EWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCET 188
Query: 137 ------SKQSTP----MGLS-LPLSTSVPD--------SAESGCSSCSTPLYDQGGPVEI 177
S S+P +GL L +S+ D S+ + P PV+I
Sbjct: 189 NVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQI 248
Query: 178 LPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFE--GHYQYKSIPVEDNHKADISS 235
LP+LYLG A ++ D+L GI ++NV+ N PN FE G + YK IP+ D+ ++S
Sbjct: 249 LPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQ 308
Query: 236 WFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSII 295
+F EAI FID ++ V VHC AGISRS T+ +AYLM+ + L++A++FVK+++S I
Sbjct: 309 FFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNI 368
Query: 296 SPNFSFMGQLLQFESQV-LAPHCSAEAGS 323
SPNF+FMGQLL FE + L+ C A S
Sbjct: 369 SPNFNFMGQLLDFERTLGLSSPCDNHASS 397
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 167 bits (424), Expect = 1e-41
Identities = 125/371 (33%), Positives = 189/371 (50%), Gaps = 45/371 (12%)
Query: 13 LRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRF-STIVRRRAKGAMGLEHIVPNAEL 71
LR L + LLLDCRS + + I G+++V + ++RR +G++ + ++P L
Sbjct: 11 LRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPL 70
Query: 72 RGRLLAGAYHAVVLLDE-----RSAALDGAKRDGTLALAAGALCREARAAQ--VFFLKGG 124
+ A V+L D+ R + + G L ++ R ++L+GG
Sbjct: 71 QPPPPA----PVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGG 126
Query: 125 YEAFSASCPELC----------SKQSTP-----MGL-SLPLSTSVPDS-AESGCSSCSTP 167
+ F A CP LC S P +GL SL L + D+ +E+ S S
Sbjct: 127 FSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCG 186
Query: 168 LYDQGG-----------PVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFE- 215
L +G PV+ILP LYLGSA ++ + L LGI ++NV+ N PN FE
Sbjct: 187 LDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEK 246
Query: 216 -GHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLM 274
G + YK IP+ D+ ++S +F EAI+FID + V VHC AG+SRS T+ +AYLM
Sbjct: 247 NGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLM 306
Query: 275 RTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQV-LAPHCSAEAGSPAMAVLDRGT 333
+ + L++A++ VK+++S ISPNF+FMGQLL FE + L S E GS A +
Sbjct: 307 QKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA--SAAS 364
Query: 334 STTTVFNFPVS 344
+ + F P S
Sbjct: 365 NPPSFFTTPTS 375
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 166 bits (420), Expect = 3e-41
Identities = 107/310 (34%), Positives = 157/310 (50%), Gaps = 25/310 (8%)
Query: 25 LLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRA-KGAMGLEHIVPNAELRGRLLAGAYHAV 83
LL+DCR + + HI ++NV I+ RR KG + + + E R R
Sbjct: 35 LLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDT 94
Query: 84 VLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSA--------SCPEL 135
V+L + S++ G L + + F+L+GG+ F A +
Sbjct: 95 VVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGS 154
Query: 136 CSKQSTPMGL----SLPLSTSVPDSAESGCSSCSTPLYDQGG----------PVEILPFL 181
CS S P+ + L +S+ ES D G PVEILPFL
Sbjct: 155 CSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFL 214
Query: 182 YLGSAYHASRKDMLDALGITALINVSANCPNHFE--GHYQYKSIPVEDNHKADISSWFNE 239
YLG A ++ D+L+ GI ++NV+ N PN FE G ++YK IP+ D+ ++S +F E
Sbjct: 215 YLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPE 274
Query: 240 AIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNF 299
AI FID + V VHC AGISRS T+ +AYLM+ + +++A++ VK ++S ISPNF
Sbjct: 275 AISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNF 334
Query: 300 SFMGQLLQFE 309
+FMGQLL FE
Sbjct: 335 NFMGQLLDFE 344
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 163 bits (413), Expect = 2e-40
Identities = 112/321 (34%), Positives = 171/321 (53%), Gaps = 20/321 (6%)
Query: 8 LDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAK-GAMGLEHIV 66
+DA L +LL L++D RSF +N+ H+ SVN+ S +V+RR + G + + ++
Sbjct: 11 MDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELI 70
Query: 67 PNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYE 126
A R ++ A VV+ D+ + D L++ L + V L GG+
Sbjct: 71 QPAA-RSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKL--DGCFDSVAILTGGFA 127
Query: 127 AFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSA 186
FS+ P LC + P L LP+S S P C + G ILP LYLGS
Sbjct: 128 TFSSCFPGLC--EGKPAAL-LPMSLSQP------CLPVPSV-----GLTRILPHLYLGSQ 173
Query: 187 YHASRKDMLDALGITALINVSANCPN-HFEGHYQYKSIPVEDNHKADISSWFNEAIDFID 245
KD++ GI+ ++N S +CP F ++ +P+ DN+ + W +++I+FID
Sbjct: 174 KDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFID 233
Query: 246 SIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQL 305
K + +V VHC AGISRSATI +AY+M+T + D+A+ FVK RR ISPNF+F+GQL
Sbjct: 234 KAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQL 293
Query: 306 LQFE-SQVLAPHCSAEAGSPA 325
L++E S L + G+P+
Sbjct: 294 LEYERSLKLLAALQGDPGTPS 314
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 159 bits (402), Expect = 4e-39
Identities = 102/301 (33%), Positives = 149/301 (49%), Gaps = 18/301 (5%)
Query: 13 LRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELR 72
L ALL + LL+D R F +N HI ++N+ S +++RR + L + +
Sbjct: 15 LVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAK 74
Query: 73 GRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASC 132
++ VV+ D+ S + D L + G L E V L GG+ FS
Sbjct: 75 HKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKL--EKSFNSVHLLAGGFAEFSRCF 132
Query: 133 PELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRK 192
P LC +ST VP C + GP ILP LYLG K
Sbjct: 133 PGLCEGKST----------LVPTCISQPCLPVANI-----GPTRILPNLYLGCQRDVLNK 177
Query: 193 DMLDALGITALINVSANCPN-HFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAG 251
+++ GI ++N S CP F + +PV D+ I W ++++DFI+ K +
Sbjct: 178 ELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASN 237
Query: 252 GRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQ 311
G V VHC AGISRSATI +AY+M+ + LDEA+ FVK++R ISPNF+F+GQLL +E +
Sbjct: 238 GCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKK 297
Query: 312 V 312
+
Sbjct: 298 I 298
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 154 bits (388), Expect = 2e-37
Identities = 97/297 (32%), Positives = 154/297 (51%), Gaps = 16/297 (5%)
Query: 25 LLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRA--KGAMGLEHIVPNAELRGRLLAGAYHA 82
+++DCR F +N HI G+V++ + + RR +G + + ++ E +
Sbjct: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKE 232
Query: 83 VVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTP 142
+++ DE + L + +L RE + V LKGG +F + LC
Sbjct: 233 IIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLV--LKGGLSSFKQNHENLCDNS--- 287
Query: 143 MGLSLPLSTSVPDSAESGCSSC-----STPLYDQGGPVEILPFLYLGSAYHASRKDMLDA 197
L L V A + S +TP + ILPFL+LG+ A D +
Sbjct: 288 --LQLQECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQR 345
Query: 198 LGITALINVSANCP-NHFE-GHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVF 255
L I +INV+ + P H+E G + YK +P D++K ++ +F EA +FI+ G +
Sbjct: 346 LNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLL 405
Query: 256 VHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQV 312
+HCQAG+SRSATI +AYLM+ R+ + +A++FVK +R IISPN +FMGQLL+FE +
Sbjct: 406 IHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 114 bits (284), Expect = 2e-25
Identities = 58/143 (40%), Positives = 83/143 (58%)
Query: 170 DQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNH 229
D GG +I L+LG AS + +L A GIT ++N + PN ++Y +P+ D
Sbjct: 23 DIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMP 82
Query: 230 KADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVK 289
A I +F+ D I S+ G VHC AG+SRSAT+C+AYLM+ + V L EA+ +VK
Sbjct: 83 HAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
Query: 290 QRRSIISPNFSFMGQLLQFESQV 312
RR +I PN F QL+ +E Q+
Sbjct: 143 ARRPVIRPNVGFWRQLIDYERQL 165
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 112 bits (279), Expect = 7e-25
Identities = 54/120 (45%), Positives = 82/120 (68%), Gaps = 2/120 (1%)
Query: 195 LDALGITALINVSANCP-NHFE-GHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGG 252
+ L I +INV+ + P H+E G + YK +P D++K ++ +F EA +FI+ G
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 253 RVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQV 312
+ +HCQAG+SRSATI +AYLM+ R+ + +A++FVK +R IISPN +FMGQLL+FE +
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 112 bits (279), Expect = 7e-25
Identities = 54/120 (45%), Positives = 82/120 (68%), Gaps = 2/120 (1%)
Query: 195 LDALGITALINVSANCP-NHFE-GHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGG 252
+ L I +INV+ + P H+E G + YK +P D++K ++ +F EA +FI+ G
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 253 RVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQV 312
+ +HCQAG+SRSATI +AYLM+ R+ + +A++FVK +R IISPN +FMGQLL+FE +
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 107 bits (267), Expect = 2e-23
Identities = 51/141 (36%), Positives = 85/141 (60%)
Query: 174 PVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADI 233
P +I ++LGS ++AS + L G+ ++NV+ N F G ++Y +I V D D+
Sbjct: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDL 367
Query: 234 SSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRS 293
+++N+ FI K G + VHC+ G+SRSA+ +AY M+ LD A+++VK+RR+
Sbjct: 368 LAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRT 427
Query: 294 IISPNFSFMGQLLQFESQVLA 314
+ PN SFM QL +++ +LA
Sbjct: 428 VTKPNPSFMRQLEEYQGILLA 448
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 102 bits (255), Expect = 4e-22
Identities = 53/136 (38%), Positives = 79/136 (58%)
Query: 174 PVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADI 233
P I LYLGS ++AS + L G+ ++NV+ N F G + Y +I V D D+
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 368
Query: 234 SSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRS 293
+ +NEA FI+ K + VHC+ G+SRSA+ +AY M+ L++A+ +VKQ+RS
Sbjct: 369 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 428
Query: 294 IISPNFSFMGQLLQFE 309
I PN FM QL ++E
Sbjct: 429 ITRPNAGFMRQLSEYE 444
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 102 bits (255), Expect = 4e-22
Identities = 53/136 (38%), Positives = 79/136 (58%)
Query: 174 PVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADI 233
P I LYLGS ++AS + L G+ ++NV+ N F G + Y +I V D D+
Sbjct: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 379
Query: 234 SSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRS 293
+ +NEA FI+ K + VHC+ G+SRSA+ +AY M+ L++A+ +VKQ+RS
Sbjct: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439
Query: 294 IISPNFSFMGQLLQFE 309
I PN FM QL ++E
Sbjct: 440 ITRPNAGFMRQLSEYE 455
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 102 bits (255), Expect = 4e-22
Identities = 53/136 (38%), Positives = 79/136 (58%)
Query: 174 PVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADI 233
P I LYLGS ++AS + L G+ ++NV+ N F G + Y +I V D D+
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 368
Query: 234 SSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRS 293
+ +NEA FI+ K + VHC+ G+SRSA+ +AY M+ L++A+ +VKQ+RS
Sbjct: 369 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 428
Query: 294 IISPNFSFMGQLLQFE 309
I PN FM QL ++E
Sbjct: 429 ITRPNAGFMRQLSEYE 444
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 100 bits (249), Expect = 2e-21
Identities = 59/172 (34%), Positives = 89/172 (51%), Gaps = 4/172 (2%)
Query: 163 SCSTPLYDQ----GGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHY 218
SC+ P+ + G +I LY+ + A+ K ML + IT +INVS N
Sbjct: 5 SCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDI 64
Query: 219 QYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNR 278
QY +PV D+ + + +F+ D I S++ GR +HC AG+SRSA +CLAYLM+ +
Sbjct: 65 QYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHA 124
Query: 279 VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLD 330
+ L +A + K R II PN F QL+ +E Q+ + SP + D
Sbjct: 125 MSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPD 176
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 95.1 bits (235), Expect = 9e-20
Identities = 54/155 (34%), Positives = 83/155 (53%)
Query: 176 EILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISS 235
+I L+L + A+ K +L + ITA++N S N F QY +PV D + +
Sbjct: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYD 83
Query: 236 WFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSII 295
+F+ D I +I GR +HC AG+SRSA++CLAYLM+ + + L +A + K RR II
Sbjct: 84 FFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII 143
Query: 296 SPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLD 330
PN F QL+ +E ++ + SP + D
Sbjct: 144 RPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPD 178
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 92.8 bits (229), Expect = 4e-19
Identities = 51/133 (38%), Positives = 71/133 (53%)
Query: 177 ILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSW 236
I P+L LGS A D L +T ++NV+ N F + YKSI + D + +I S+
Sbjct: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
Query: 237 FNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIIS 296
F E +FI+ K G V VHC AG+SR+A I + +LM + + AF VK R I
Sbjct: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
Query: 297 PNFSFMGQLLQFE 309
PN FM QL ++
Sbjct: 189 PNSGFMEQLRTYQ 201
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 89.4 bits (220), Expect = 5e-18
Identities = 60/148 (40%), Positives = 86/148 (58%), Gaps = 11/148 (7%)
Query: 176 EILPFLYLGSAYHASRKDMLDAL---GITALI----NVSANC--PNHFEGHYQYKSIPVE 226
EILP L+LG Y ++ K L L GIT +I N+ AN PN F+ ++Y + +
Sbjct: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
Query: 227 DNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFE 286
DN +I +F +FID GG+V VH AGISRSA +AY+M T +K +AF
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 287 FVKQRRSIISPNFSFMGQLLQFESQVLA 314
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 89.4 bits (220), Expect = 5e-18
Identities = 60/148 (40%), Positives = 86/148 (58%), Gaps = 11/148 (7%)
Query: 176 EILPFLYLGSAYHASRKDMLDAL---GITALI----NVSANC--PNHFEGHYQYKSIPVE 226
EILP L+LG Y ++ K L L GIT +I N+ AN PN F+ ++Y + +
Sbjct: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
Query: 227 DNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFE 286
DN +I +F +FID GG+V VH AGISRSA +AY+M T +K +AF
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 287 FVKQRRSIISPNFSFMGQLLQFESQVLA 314
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 89.4 bits (220), Expect = 5e-18
Identities = 60/148 (40%), Positives = 86/148 (58%), Gaps = 11/148 (7%)
Query: 176 EILPFLYLGSAYHASRKDMLDAL---GITALI----NVSANC--PNHFEGHYQYKSIPVE 226
EILP L+LG Y ++ K L L GIT +I N+ AN PN F+ ++Y + +
Sbjct: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
Query: 227 DNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFE 286
DN +I +F +FID GG+V VH AGISRSA +AY+M T +K +AF
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 287 FVKQRRSIISPNFSFMGQLLQFESQVLA 314
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 88.2 bits (217), Expect = 1e-17
Identities = 53/161 (32%), Positives = 80/161 (49%), Gaps = 2/161 (1%)
Query: 157 AESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEG 216
AE+G ++P+ V + P L+LGSA A ++ L G+T +NVS P
Sbjct: 4 AEAGRRGAASPVPPP--LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAP 61
Query: 217 HYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRT 276
+PV D+ D+ + +++ AGG V+C+ G SRSA +C AYLMR
Sbjct: 62 GVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRH 121
Query: 277 NRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHC 317
+ L +AF+ VK R + PN F QL ++E + A C
Sbjct: 122 RGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSC 162
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 87.8 bits (216), Expect = 1e-17
Identities = 66/190 (34%), Positives = 97/190 (51%), Gaps = 20/190 (10%)
Query: 131 SCPELCSK-QSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHA 189
S PEL + ++TP P + + +G SSCS E+ P L++G A A
Sbjct: 5 SLPELGGEDKATPC----PSILELEELLRAGKSSCSRV-------DEVWPNLFIGDAATA 53
Query: 190 SRKDMLDALGITALINVSAN---C---PNHFEGHYQYKSIPVEDNHKADISSWFNEAIDF 243
+ + L LGIT ++N + C P+ + Y +P D DIS++F+ A DF
Sbjct: 54 NNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADF 113
Query: 244 IDSIKNA-GGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFM 302
I N G +V VHC G+SRSAT+ LAYLM R+ L +A V+Q R + PN F+
Sbjct: 114 IHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVF-PNRGFL 172
Query: 303 GQLLQFESQV 312
QL + + Q+
Sbjct: 173 HQLCRLDQQL 182
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 87.4 bits (215), Expect = 2e-17
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 7/143 (4%)
Query: 176 EILPFLYLGSAYHASRKDMLDALGITALINVSAN----CPNHFEG-HYQYKSIPVEDNHK 230
E+ P LYLG A+ + L LGIT ++N S + P +EG +Y + D+
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
Query: 231 ADISSWFNEAIDFID-SIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVK 289
D+S F A DFI ++ GG++ VHC G+SRSAT+ LAYLM + + L EA + VK
Sbjct: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
Query: 290 QRRSIISPNFSFMGQLLQFESQV 312
R II PN F+ QLL + ++
Sbjct: 184 DHRGII-PNRGFLRQLLALDRRL 205
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 83.6 bits (205), Expect = 3e-16
Identities = 50/147 (34%), Positives = 76/147 (51%), Gaps = 11/147 (7%)
Query: 176 EILPFLYLGSAYHASRKDMLDALGITALIN---------VSANCPNHFEGHYQYKSIPVE 226
E+ P +Y+G+A A L LGIT ++N V+ N + + Y I
Sbjct: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
Query: 227 DNHKADISSWFNEAIDFID-SIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAF 285
D + ++S++F A DFID ++ GRV VHC+ G SRS T+ +AYLM ++ + A
Sbjct: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
Query: 286 EFVKQRRSIISPNFSFMGQLLQFESQV 312
V+Q R I PN F+ QL Q ++
Sbjct: 152 SIVRQNRE-IGPNDGFLAQLCQLNDRL 177
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 82.4 bits (202), Expect = 6e-16
Identities = 43/138 (31%), Positives = 73/138 (52%)
Query: 177 ILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSW 236
I P LYLGS ++A+ + L +T ++N++ N + + Y ++ + D A +
Sbjct: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
Query: 237 FNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIIS 296
+ E FI++ + G V VHC+ G+SRSA LAY M+ L++A V++ R I
Sbjct: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
Query: 297 PNFSFMGQLLQFESQVLA 314
PN F+ QL ++ + A
Sbjct: 452 PNPGFLRQLQIYQGILTA 469
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 81.3 bits (199), Expect = 1e-15
Identities = 51/136 (37%), Positives = 67/136 (49%), Gaps = 1/136 (0%)
Query: 173 GPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKAD 232
G ++LP LYLG+ A D L IT +I++ + P Y IPV D +
Sbjct: 4 GMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHES-PQPLLQDITYLRIPVADTPEVP 62
Query: 233 ISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRR 292
I F E I+FI + GG VHC AGISRS TI AY+M + + E +K R
Sbjct: 63 IKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATR 122
Query: 293 SIISPNFSFMGQLLQF 308
I +PN F QL +F
Sbjct: 123 PIANPNPGFRQQLEEF 138
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,125,285
Number of Sequences: 37866
Number of extensions: 558029
Number of successful extensions: 1549
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1434
Number of HSP's gapped (non-prelim): 92
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.