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Search of human proteins with 47059042
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens]
(361 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens] 734 0.0
gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens] 728 0.0
gi|122939167 WDR45-like [Homo sapiens] 320 1e-87
gi|157388939 WD repeat domain, phosphoinositide interacting 1 [H... 110 1e-24
gi|75677331 WD repeat domain, phosphoinositide interacting 2 iso... 100 2e-21
gi|54111428 WD repeat domain, phosphoinositide interacting 2 iso... 100 2e-21
gi|75677340 WD repeat domain, phosphoinositide interacting 2 iso... 96 5e-20
gi|75677329 WD repeat domain, phosphoinositide interacting 2 iso... 96 5e-20
gi|7661580 WD repeat domain, phosphoinositide interacting 2 isof... 96 5e-20
gi|18874090 WD repeat domain 48 [Homo sapiens] 39 0.009
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 39 0.009
gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Ho... 38 0.012
gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Ho... 38 0.012
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ... 36 0.061
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ... 36 0.061
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ... 36 0.061
gi|56243583 WD repeat domain 18 [Homo sapiens] 35 0.080
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 35 0.10
gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens] 35 0.14
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 34 0.18
gi|171846278 leucine-rich repeat kinase 2 [Homo sapiens] 34 0.18
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 34 0.18
gi|169234742 NACHT and WD repeat domain containing 1 [Homo sapiens] 33 0.30
gi|32699064 WD repeat domain 53 [Homo sapiens] 33 0.52
gi|19913369 transducin beta-like 3 [Homo sapiens] 33 0.52
gi|16554629 WD repeat domain 5 [Homo sapiens] 32 0.68
gi|16554627 WD repeat domain 5 [Homo sapiens] 32 0.68
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 32 0.68
gi|23199987 WD repeat domain 5B [Homo sapiens] 32 0.68
gi|55743075 angio-associated, migratory cell protein [Homo sapiens] 32 0.88
>gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens]
Length = 361
Score = 734 bits (1896), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS 60
MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS
Sbjct: 1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS 60
Query: 61 NLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL 120
NLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL
Sbjct: 61 NLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL 120
Query: 121 KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP 180
KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP
Sbjct: 121 KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP 180
Query: 181 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT 240
GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT
Sbjct: 181 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT 240
Query: 241 LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS 300
LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS
Sbjct: 241 LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS 300
Query: 301 FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD 360
FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD
Sbjct: 301 FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD 360
Query: 361 F 361
F
Sbjct: 361 F 361
>gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens]
Length = 360
Score = 728 bits (1880), Expect = 0.0
Identities = 360/361 (99%), Positives = 360/361 (99%), Gaps = 1/361 (0%)
Query: 1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS 60
MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS
Sbjct: 1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS 60
Query: 61 NLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL 120
NLLALVGGGSSPKFSEIS VLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL
Sbjct: 61 NLLALVGGGSSPKFSEIS-VLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL 119
Query: 121 KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP 180
KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP
Sbjct: 120 KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP 179
Query: 181 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT 240
GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT
Sbjct: 180 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT 239
Query: 241 LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS 300
LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS
Sbjct: 240 LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS 299
Query: 301 FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD 360
FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD
Sbjct: 300 FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD 359
Query: 361 F 361
F
Sbjct: 360 F 360
>gi|122939167 WDR45-like [Homo sapiens]
Length = 344
Score = 320 bits (820), Expect = 1e-87
Identities = 166/351 (47%), Positives = 227/351 (64%), Gaps = 20/351 (5%)
Query: 8 GVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVG 67
G+ FNQD CF C ME G R+YN +PL EK + + G +G VEML R N LALVG
Sbjct: 12 GLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEMLFRCNYLALVG 70
Query: 68 GGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVY 127
GG PK+ + V+IWDD K+K V+E F+ V +V++R D+IV+VL + I V+
Sbjct: 71 GGKKPKYPP-NKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVF 123
Query: 128 SFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPF 187
+F NP +L F+T NPKGLC LCP+ LL FPG G +QLVDLAST+ P
Sbjct: 124 TFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTE----KPPV 179
Query: 188 TINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFS 247
I AH+ ++C++LN GT +A+AS+KGTLIR+FDT S + ELRRG+ A +YCINF+
Sbjct: 180 DIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFN 239
Query: 248 HDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASFTVPAES 307
D+S +C SSD GTVHIFA +D + N++S+LA + +Y S+WS + F VP+ S
Sbjct: 240 QDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKWSFSKFQVPSGS 295
Query: 308 ACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDD 358
CICAFG N+VIAIC DG+++K++F P G C R+ + +L++ DD
Sbjct: 296 PCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDD 342
>gi|157388939 WD repeat domain, phosphoinositide interacting 1 [Homo
sapiens]
Length = 446
Score = 110 bits (276), Expect = 1e-24
Identities = 78/265 (29%), Positives = 133/265 (50%), Gaps = 22/265 (8%)
Query: 14 FNQDQSCFCCAMETGVRIYNVEPL--MEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSS 71
FNQD + + G +++++ + +++ H +E + + +VE L S+L+ +V +
Sbjct: 22 FNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNE-IPDVYIVERLFSSSLVVVVSH-TK 79
Query: 72 PKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPD 131
P+ + K + ++++ +LS+R+ ++++ L+ IY+++ D
Sbjct: 80 PRQMNVYHF-----------KKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKD 128
Query: 132 NPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGH-KCGSLQLVDLASTKPGTSSAPFTIN 190
D NP GLC L + L +PG G + L D S K TI
Sbjct: 129 MKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK-----TVCTIA 183
Query: 191 AHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDP-ATLYCINFSHD 249
AH+ +A ++ N G+ +ASAS+KGT+IR+F +KL E RRG T+ + FS D
Sbjct: 184 AHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMD 243
Query: 250 SSFLCASSDKGTVHIFALKDTRLNR 274
S FLCASS+ TVHIF L+ +R
Sbjct: 244 SQFLCASSNTETVHIFKLEQVTNSR 268
>gi|75677331 WD repeat domain, phosphoinositide interacting 2
isoform d [Homo sapiens]
Length = 425
Score = 100 bits (249), Expect = 2e-21
Identities = 70/261 (26%), Positives = 127/261 (48%), Gaps = 20/261 (7%)
Query: 14 FNQDQSCFCCAMETGVRIYNVEPLMEKGHL-DHEQVGSMGLVEMLHRSNLLALVGGGSSP 72
FNQD + ++G + +++ + + + + + +VE L S+L+A+V +
Sbjct: 20 FNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPR 79
Query: 73 KFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDN 132
K K + ++++ +L+V++ ++++ L+ +Y+++ D
Sbjct: 80 KLKVCHF------------KKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDM 127
Query: 133 PRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINA 191
+T NP GLC L + + L +PG G +Q+ D + + A I A
Sbjct: 128 KVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPA 182
Query: 192 HQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDS 250
H S +A ++ + GT +A+AS+KGT+IR+F +KL E RRG C + FS D
Sbjct: 183 HDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDG 242
Query: 251 SFLCASSDKGTVHIFALKDTR 271
FL ASS+ TVHIF L+ +
Sbjct: 243 MFLSASSNTETVHIFKLETVK 263
>gi|54111428 WD repeat domain, phosphoinositide interacting 2
isoform b [Homo sapiens]
Length = 436
Score = 100 bits (249), Expect = 2e-21
Identities = 70/261 (26%), Positives = 127/261 (48%), Gaps = 20/261 (7%)
Query: 14 FNQDQSCFCCAMETGVRIYNVEPLMEKGHL-DHEQVGSMGLVEMLHRSNLLALVGGGSSP 72
FNQD + ++G + +++ + + + + + +VE L S+L+A+V +
Sbjct: 20 FNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPR 79
Query: 73 KFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDN 132
K K + ++++ +L+V++ ++++ L+ +Y+++ D
Sbjct: 80 KLKVCHF------------KKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDM 127
Query: 133 PRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINA 191
+T NP GLC L + + L +PG G +Q+ D + + A I A
Sbjct: 128 KVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPA 182
Query: 192 HQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDS 250
H S +A ++ + GT +A+AS+KGT+IR+F +KL E RRG C + FS D
Sbjct: 183 HDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDG 242
Query: 251 SFLCASSDKGTVHIFALKDTR 271
FL ASS+ TVHIF L+ +
Sbjct: 243 MFLSASSNTETVHIFKLETVK 263
>gi|75677340 WD repeat domain, phosphoinositide interacting 2
isoform e [Homo sapiens]
Length = 384
Score = 95.9 bits (237), Expect = 5e-20
Identities = 56/177 (31%), Positives = 96/177 (54%), Gaps = 7/177 (3%)
Query: 97 VLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLE 156
+ ++++ +L+V++ ++++ L+ +Y+++ D +T NP GLC L + +
Sbjct: 51 ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINND 110
Query: 157 KQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKG 215
L +PG G +Q+ D + + A I AH S +A ++ + GT +A+AS+KG
Sbjct: 111 NCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFDASGTKLATASEKG 165
Query: 216 TLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGTVHIFALKDTR 271
T+IR+F +KL E RRG C + FS D FL ASS+ TVHIF L+ +
Sbjct: 166 TVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK 222
>gi|75677329 WD repeat domain, phosphoinositide interacting 2
isoform c [Homo sapiens]
Length = 443
Score = 95.9 bits (237), Expect = 5e-20
Identities = 56/177 (31%), Positives = 96/177 (54%), Gaps = 7/177 (3%)
Query: 97 VLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLE 156
+ ++++ +L+V++ ++++ L+ +Y+++ D +T NP GLC L + +
Sbjct: 110 ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINND 169
Query: 157 KQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKG 215
L +PG G +Q+ D + + A I AH S +A ++ + GT +A+AS+KG
Sbjct: 170 NCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFDASGTKLATASEKG 224
Query: 216 TLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGTVHIFALKDTR 271
T+IR+F +KL E RRG C + FS D FL ASS+ TVHIF L+ +
Sbjct: 225 TVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK 281
>gi|7661580 WD repeat domain, phosphoinositide interacting 2 isoform
a [Homo sapiens]
Length = 454
Score = 95.9 bits (237), Expect = 5e-20
Identities = 56/177 (31%), Positives = 96/177 (54%), Gaps = 7/177 (3%)
Query: 97 VLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLE 156
+ ++++ +L+V++ ++++ L+ +Y+++ D +T NP GLC L + +
Sbjct: 110 ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINND 169
Query: 157 KQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKG 215
L +PG G +Q+ D + + A I AH S +A ++ + GT +A+AS+KG
Sbjct: 170 NCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFDASGTKLATASEKG 224
Query: 216 TLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGTVHIFALKDTR 271
T+IR+F +KL E RRG C + FS D FL ASS+ TVHIF L+ +
Sbjct: 225 TVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK 281
>gi|18874090 WD repeat domain 48 [Homo sapiens]
Length = 677
Score = 38.5 bits (88), Expect = 0.009
Identities = 23/96 (23%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 176 ASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRG 235
A T + +++ ++ I +++NQ GT++ S S + ++R++D ++ KL++L+
Sbjct: 151 ALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTE-KVLRVWDPRTCAKLMKLKGH 209
Query: 236 TDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTR 271
TD +N D + + S GT+ +++L R
Sbjct: 210 TDNVKALLLN--RDGTQCLSGSSDGTIRLWSLGQQR 243
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 38.5 bits (88), Expect = 0.009
Identities = 18/87 (20%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 189 INAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSH 248
++ HQ + +S G+++ ++ + +R++D K +++ G +YC + S
Sbjct: 149 LSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSG-HLQWVYCCSISP 207
Query: 249 DSSFLCASSDKGTVHIFALKDTRLNRR 275
D S LC+++ + +V +++++ L R+
Sbjct: 208 DCSMLCSAAGEKSVFLWSMRSYTLIRK 234
>gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Homo
sapiens]
Length = 928
Score = 38.1 bits (87), Expect = 0.012
Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 9/86 (10%)
Query: 191 AHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSK---------EKLVELRRGTDPATL 241
AH+ + C++ N G ++ + G +F + L L RG A +
Sbjct: 349 AHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLYTLHRGETEAKV 408
Query: 242 YCINFSHDSSFLCASSDKGTVHIFAL 267
I FSHD ++ S+ +GT H+F +
Sbjct: 409 QDICFSHDCRWVVVSTLRGTSHVFPI 434
>gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Homo
sapiens]
Length = 913
Score = 38.1 bits (87), Expect = 0.012
Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 9/86 (10%)
Query: 191 AHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSK---------EKLVELRRGTDPATL 241
AH+ + C++ N G ++ + G +F + L L RG A +
Sbjct: 349 AHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLYTLHRGETEAKV 408
Query: 242 YCINFSHDSSFLCASSDKGTVHIFAL 267
I FSHD ++ S+ +GT H+F +
Sbjct: 409 QDICFSHDCRWVVVSTLRGTSHVFPI 434
>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
sapiens]
Length = 769
Score = 35.8 bits (81), Expect = 0.061
Identities = 44/158 (27%), Positives = 64/158 (40%), Gaps = 25/158 (15%)
Query: 123 RIYVYSFPDNPRKLFEFD--TRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP 180
+I+ S P + + + D RDN C L P + L+V G + +L + DLAS P
Sbjct: 507 KIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD-GRTLIV--GGEASTLTIWDLASPTP 563
Query: 181 G-----TSSAP--FTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELR 233
TSSAP + + C S G + TL+R F
Sbjct: 564 RIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGH--------- 614
Query: 234 RGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTR 271
TD A+ CI+ SHD + L TV + L++ R
Sbjct: 615 --TDGAS--CIDISHDGTKLWTGGLDNTVRSWDLREGR 648
>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
sapiens]
Length = 760
Score = 35.8 bits (81), Expect = 0.061
Identities = 44/158 (27%), Positives = 64/158 (40%), Gaps = 25/158 (15%)
Query: 123 RIYVYSFPDNPRKLFEFD--TRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP 180
+I+ S P + + + D RDN C L P + L+V G + +L + DLAS P
Sbjct: 498 KIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD-GRTLIV--GGEASTLTIWDLASPTP 554
Query: 181 G-----TSSAP--FTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELR 233
TSSAP + + C S G + TL+R F
Sbjct: 555 RIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGH--------- 605
Query: 234 RGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTR 271
TD A+ CI+ SHD + L TV + L++ R
Sbjct: 606 --TDGAS--CIDISHDGTKLWTGGLDNTVRSWDLREGR 639
>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
sapiens]
Length = 772
Score = 35.8 bits (81), Expect = 0.061
Identities = 44/158 (27%), Positives = 64/158 (40%), Gaps = 25/158 (15%)
Query: 123 RIYVYSFPDNPRKLFEFD--TRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP 180
+I+ S P + + + D RDN C L P + L+V G + +L + DLAS P
Sbjct: 510 KIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPD-GRTLIV--GGEASTLTIWDLASPTP 566
Query: 181 G-----TSSAP--FTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELR 233
TSSAP + + C S G + TL+R F
Sbjct: 567 RIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGH--------- 617
Query: 234 RGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTR 271
TD A+ CI+ SHD + L TV + L++ R
Sbjct: 618 --TDGAS--CIDISHDGTKLWTGGLDNTVRSWDLREGR 651
>gi|56243583 WD repeat domain 18 [Homo sapiens]
Length = 432
Score = 35.4 bits (80), Expect = 0.080
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 10/75 (13%)
Query: 161 VFPGHKCGSLQLVDLASTKPGTSSAPF--------TINAHQSDIACVSLNQPGTVVASAS 212
+F G GS+ VDL T PG F H++ + C+S++ G+V+ S S
Sbjct: 230 MFCGGSEGSIFQVDLF-TWPGQRERSFHPEQDAGKVFKGHRNQVTCLSVSTDGSVLLSGS 288
Query: 213 QKGTLIRLFDTQSKE 227
T +RL+D QSK+
Sbjct: 289 HDET-VRLWDVQSKQ 302
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 35.0 bits (79), Expect = 0.10
Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 12/141 (8%)
Query: 134 RKLFEFDTRDNPKGLCD----LCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPFTI 189
RK ++ +DN + D +C S + ++L G + G +++ + S G F
Sbjct: 249 RKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLA-TGAQDGKIKVWKIQS---GQCLRRFE- 303
Query: 190 NAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHD 249
AH + C+S ++ + + SAS T IR+ +S + L E R + + + F+ D
Sbjct: 304 RAHSKGVTCLSFSKDSSQILSASFDQT-IRIHGLKSGKTLKEFRGHS--SFVNEATFTQD 360
Query: 250 SSFLCASSDKGTVHIFALKDT 270
++ ++S GTV I+ +K T
Sbjct: 361 GHYIISASSDGTVKIWNMKTT 381
>gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens]
Length = 606
Score = 34.7 bits (78), Expect = 0.14
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 187 FTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRG-TDPATLYCIN 245
FTI H + CV + G A+AS G I ++D ++ EK+ L +Y I+
Sbjct: 183 FTIGDHSRFVNCVRFSPDGNRFATASADGQ-IYIYDGKTGEKVCALGGSKAHDGGIYAIS 241
Query: 246 FSHDSSFLCASSDKGTVHIF 265
+S DS+ L ++S T I+
Sbjct: 242 WSPDSTHLLSASGDKTSKIW 261
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 34.3 bits (77), Expect = 0.18
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 188 TINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFS 247
T H+ + V NQ GT++AS S T +R++ +KE ELR + CI+++
Sbjct: 229 TFTGHREWVRMVRPNQDGTLIASCSNDQT-VRVWVVATKECKAELRE--HEHVVECISWA 285
Query: 248 HDSSFLCASSDKGT 261
+SS+ S G+
Sbjct: 286 PESSYSSISEATGS 299
>gi|171846278 leucine-rich repeat kinase 2 [Homo sapiens]
Length = 2527
Score = 34.3 bits (77), Expect = 0.18
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 15/119 (12%)
Query: 168 GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLN----QPGTVVASASQKGTLIRLFDT 223
G L +DL +T+ TS S I C++L + + + S +Q GTL+ + +T
Sbjct: 2177 GQLSFLDL-NTEGYTSE-----EVADSRILCLALVHLPVEKESWIVSGTQSGTLL-VINT 2229
Query: 224 QSKEKLVELRRGTDPAT-LYCINFSHDS---SFLCASSDKGTVHIFALKDTRLNRRSAL 278
+ +K L + TD T LYC +FS S +FL + G + IF K +L + L
Sbjct: 2230 EDGKKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGTADGKLAIFEDKTVKLKGAAPL 2288
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 34.3 bits (77), Expect = 0.18
Identities = 23/95 (24%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 181 GTSSAPFTINAHQSDIACVSLNQPGT---VVASASQKGTLIRLFDTQSKEKLVELRRGTD 237
G+SS FT+ H+ + C+ G +++ A + L++++D Q+K + L
Sbjct: 173 GSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDR--LVKIWDYQNKTCVQTLEGHAQ 230
Query: 238 PATLYCINFSHDSSFLCASSDKGTVHIFALKDTRL 272
+ C +F + + S+ GTV I+ RL
Sbjct: 231 --NVSCASFHPELPIIITGSEDGTVRIWHSSTYRL 263
>gi|169234742 NACHT and WD repeat domain containing 1 [Homo sapiens]
Length = 1429
Score = 33.5 bits (75), Expect = 0.30
Identities = 29/127 (22%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 168 GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKE 227
G L L + A++K F + H+S +ACV ++ +V S S+ L+ L+D Q+++
Sbjct: 1234 GDLFLYECATSKA------FPLETHRSRVACVEVSHKEQLVVSGSE-DALLCLWDLQARK 1286
Query: 228 KLVELRRGTDPAT-LYCINFSHDSSFLCASSDKGTVHIFALKD-TRLNRRSALARVGKVG 285
E+ + + C FS D ++ ++ ++++ D T L + A V ++
Sbjct: 1287 WKFEMSYTSSYCRGVQCACFSKDDKYVYVGLKDRSILVWSVLDGTLLTVQFVHAVVNRII 1346
Query: 286 PMIGQYV 292
P ++
Sbjct: 1347 PTTSGFI 1353
>gi|32699064 WD repeat domain 53 [Homo sapiens]
Length = 358
Score = 32.7 bits (73), Expect = 0.52
Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 5/66 (7%)
Query: 169 SLQLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEK 228
++ ++D+ S K + ++ +I C+SLNQ ++ASA G I++ D ++K+
Sbjct: 74 TISVLDVRSLKDSLDH----FHVNEEEINCLSLNQTENLLASADDSGA-IKILDLENKKV 128
Query: 229 LVELRR 234
+ L+R
Sbjct: 129 IRSLKR 134
>gi|19913369 transducin beta-like 3 [Homo sapiens]
Length = 808
Score = 32.7 bits (73), Expect = 0.52
Identities = 35/130 (26%), Positives = 54/130 (41%), Gaps = 18/130 (13%)
Query: 152 CPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAP----------FTINAHQSDIACVSL 201
C L++ LV C +++L L ++AP T H DI V++
Sbjct: 429 CSRLKESFLVTGSQDC-TVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAI 487
Query: 202 NQPGTVVASASQKGT--LIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDK 259
++A+ SQ T L L Q RRG L+C+ FS L +S
Sbjct: 488 APNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRG-----LWCVQFSPMDQVLATASAD 542
Query: 260 GTVHIFALKD 269
GT+ ++AL+D
Sbjct: 543 GTIKLWALQD 552
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 32.3 bits (72), Expect = 0.68
Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 188 TINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFS 247
TI+ H+ I+ V+ + ++ SAS TL +++D S + L L+ ++ ++C NF+
Sbjct: 82 TISGHKLGISDVAWSSDSNLLVSASDDKTL-KIWDVSSGKCLKTLKGHSN--YVFCCNFN 138
Query: 248 HDSSFLCASSDKGTVHIFALK 268
S+ + + S +V I+ +K
Sbjct: 139 PQSNLIVSGSFDESVRIWDVK 159
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 32.3 bits (72), Expect = 0.68
Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 188 TINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFS 247
TI+ H+ I+ V+ + ++ SAS TL +++D S + L L+ ++ ++C NF+
Sbjct: 82 TISGHKLGISDVAWSSDSNLLVSASDDKTL-KIWDVSSGKCLKTLKGHSN--YVFCCNFN 138
Query: 248 HDSSFLCASSDKGTVHIFALK 268
S+ + + S +V I+ +K
Sbjct: 139 PQSNLIVSGSFDESVRIWDVK 159
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 32.3 bits (72), Expect = 0.68
Identities = 35/129 (27%), Positives = 57/129 (44%), Gaps = 21/129 (16%)
Query: 148 LCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPFTINAHQSDIACVSL--NQPG 205
LC ++Q+++ G K G LQL DLAS + TI+AH + +SL +Q G
Sbjct: 458 LCSFFVPGDRQVVI--GTKTGKLQLYDLAS-----GNLLETIDAHDGALWSMSLSPDQRG 510
Query: 206 TVVASASQKGTLIRLFD---------TQSKEKLVELRRGTDPATLYCINFSHDSSFLCAS 256
V A + ++ +D TQ + + + R + C+++S + L S
Sbjct: 511 FVTGGADKS---VKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVS 567
Query: 257 SDKGTVHIF 265
TV IF
Sbjct: 568 LLDCTVKIF 576
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 32.3 bits (72), Expect = 0.68
Identities = 23/81 (28%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 188 TINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFS 247
T+ H +I+ V+ + + + SAS TL +L+D +S + L L+ ++ ++C NF+
Sbjct: 78 TLYGHNLEISDVAWSSDSSRLVSASDDKTL-KLWDVRSGKCLKTLKGHSN--YVFCCNFN 134
Query: 248 HDSSFLCASSDKGTVHIFALK 268
S+ + + S TV I+ +K
Sbjct: 135 PPSNLIISGSFDETVKIWEVK 155
>gi|55743075 angio-associated, migratory cell protein [Homo sapiens]
Length = 434
Score = 32.0 bits (71), Expect = 0.88
Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 181 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT 240
G + T H + + CVSL+ +A + ++ E L E D T
Sbjct: 79 GPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVT 138
Query: 241 LYCINFSHDSSFLCASSDKGTVHIFALKDTR 271
C FSHDS+ + G + ++ + DT+
Sbjct: 139 --CAGFSHDSTLVATGDMSGLLKVWQV-DTK 166
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,827,923
Number of Sequences: 37866
Number of extensions: 589127
Number of successful extensions: 1200
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1145
Number of HSP's gapped (non-prelim): 71
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.