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Search of human proteins with 46852388
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
(1150 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 2295 0.0
gi|40548408 p30 DBC protein [Homo sapiens] 309 9e-84
gi|24432106 p30 DBC protein [Homo sapiens] 309 9e-84
gi|221219020 NYD-SP11 protein [Homo sapiens] 82 2e-15
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 80 1e-14
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 79 2e-14
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 79 2e-14
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 78 4e-14
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 76 2e-13
gi|148746195 trichohyalin [Homo sapiens] 75 3e-13
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 75 5e-13
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 74 8e-13
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 72 2e-12
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 71 5e-12
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 71 5e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 71 7e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 71 7e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 9e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 70 1e-11
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 70 1e-11
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 69 2e-11
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 69 2e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 69 3e-11
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 69 3e-11
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 68 6e-11
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 67 1e-10
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 67 1e-10
gi|4557509 cylicin 2 [Homo sapiens] 66 2e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 66 2e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 66 2e-10
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 2295 bits (5947), Expect = 0.0
Identities = 1150/1150 (100%), Positives = 1150/1150 (100%)
Query: 1 MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPAN 60
MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPAN
Sbjct: 1 MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPAN 60
Query: 61 YQLTQTAALQQQAAAAAAALQQQYSQPQQALYSVQQQLQQPQQTLLTQPAVALPTSLSLS 120
YQLTQTAALQQQAAAAAAALQQQYSQPQQALYSVQQQLQQPQQTLLTQPAVALPTSLSLS
Sbjct: 61 YQLTQTAALQQQAAAAAAALQQQYSQPQQALYSVQQQLQQPQQTLLTQPAVALPTSLSLS 120
Query: 121 TPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTP 180
TPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTP
Sbjct: 121 TPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTP 180
Query: 181 QVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQT 240
QVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQT
Sbjct: 181 QVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQT 240
Query: 241 QPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSR 300
QPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSR
Sbjct: 241 QPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSR 300
Query: 301 FSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVP 360
FSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVP
Sbjct: 301 FSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVP 360
Query: 361 RYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFY 420
RYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFY
Sbjct: 361 RYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFY 420
Query: 421 VMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQH 480
VMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQH
Sbjct: 421 VMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQH 480
Query: 481 PARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCT 540
PARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCT
Sbjct: 481 PARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCT 540
Query: 541 QWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEK 600
QWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEK
Sbjct: 541 QWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEK 600
Query: 601 LQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKS 660
LQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKS
Sbjct: 601 LQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKS 660
Query: 661 QLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR 720
QLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR
Sbjct: 661 QLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR 720
Query: 721 YILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQR 780
YILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQR
Sbjct: 721 YILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQR 780
Query: 781 DFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKE 840
DFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKE
Sbjct: 781 DFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKE 840
Query: 841 DRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDIN 900
DRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDIN
Sbjct: 841 DRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDIN 900
Query: 901 RYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQ 960
RYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQ
Sbjct: 901 RYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQ 960
Query: 961 VKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEE 1020
VKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEE
Sbjct: 961 VKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEE 1020
Query: 1021 NVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLS 1080
NVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLS
Sbjct: 1021 NVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLS 1080
Query: 1081 GELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKD 1140
GELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKD
Sbjct: 1081 GELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKD 1140
Query: 1141 QKSKENGASV 1150
QKSKENGASV
Sbjct: 1141 QKSKENGASV 1150
>gi|40548408 p30 DBC protein [Homo sapiens]
Length = 923
Score = 309 bits (792), Expect = 9e-84
Identities = 185/473 (39%), Positives = 258/473 (54%), Gaps = 59/473 (12%)
Query: 145 QKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQR 204
+KQRVFTG+VT LHD FG VDE+VFFQLS VKG+ PQ+G++VLV+A YNP WNA +
Sbjct: 53 EKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVK 112
Query: 205 IQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQ 264
+QTL N QPLLK+P L +A Q Q +L A Q
Sbjct: 113 VQTLSN------QPLLKSPAPPLLHVA--------ALGQKQGILGA-------------Q 145
Query: 265 PQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERER 324
PQ L+ QP + L + Q L +RF R G R DD ++ +
Sbjct: 146 PQ-LIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNRFPARGPHGRLDQGRSDDYDSKKRK 204
Query: 325 ERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRR 384
+R ++ PR + +P Y V + +++D P CD +EL+RR
Sbjct: 205 QRAGGEPWGAKK-------PRHD-----------LPPYRVHLTPYTVDSPICDFLELQRR 246
Query: 385 YQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHL 444
Y++L +PSDF +W+ AFPLS+PF L + V E E+ A D+D
Sbjct: 247 YRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQV-SSEKEAAPDAGAEPITADSDPA 305
Query: 445 YSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHW 504
YS+KV+L++SP +E+LY +D E R+ +HP + +KFL+G K ++EA+ +GG W
Sbjct: 306 YSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRK-EEEAVLVGGEW 364
Query: 505 SPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPA 564
SPSLDG DP+ DP VL++TAIRC +A TGIDLS CT+W+RFAE +Y +P P
Sbjct: 365 SPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGP-------PR 417
Query: 565 HVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEK 617
++TVV++ PDVW +PT EWE L QQ + +EA GE + E+
Sbjct: 418 RLQTVVVYLPDVWTIMPTLEEWEALC----QQKAAEAAPPTQEAQGETEPTEQ 466
Score = 192 bits (487), Expect = 2e-48
Identities = 146/473 (30%), Positives = 234/473 (49%), Gaps = 35/473 (7%)
Query: 676 KEEQKELEKSEKEED--EDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHP 733
+E Q E E +E+ D E S + E E Q+E + E P EPA+I P
Sbjct: 455 QEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPP-PLEPAVIARP 513
Query: 734 NWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSL 793
C +SL +++ R + SFEV + AELF EMLQRDFG R+YK LLSL
Sbjct: 514 G---------CVNLSLHGIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSL 563
Query: 794 PEK---EDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDK 850
PEK + EK++ +K++ K+++ +++ EPK + + G + + KED
Sbjct: 564 PEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPL----KEDG 619
Query: 851 RKDDSKDDDETEEDNNQDEYDPMEAEEAEDEE-----DDRDEEEMTKRDDKRDINRYCKE 905
EE+ + E E A D E DD +EE + + ++
Sbjct: 620 LLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASN 679
Query: 906 RPS------KDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRA 959
+ +D KE + D L+AFV+FD + CGYL +DLE IL TLG+ LS
Sbjct: 680 QSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAE 739
Query: 960 QVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVE 1019
Q K+L+++VV + C YR L + ++ + E E + GN LLP P +
Sbjct: 740 QAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPE---EVLFGNLDLLPPPGKSTKPGAAP 796
Query: 1020 -ENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKS 1078
E+ L+ +NG++++VGSLLQ+ E+ + R +E K+ LE K +E E +NK+
Sbjct: 797 TEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKT 856
Query: 1079 LSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKK 1131
L+ E++E++ L++ +E + +E Q + + + R L+ + EI V++K
Sbjct: 857 LAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEK 909
>gi|24432106 p30 DBC protein [Homo sapiens]
Length = 923
Score = 309 bits (792), Expect = 9e-84
Identities = 185/473 (39%), Positives = 258/473 (54%), Gaps = 59/473 (12%)
Query: 145 QKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQR 204
+KQRVFTG+VT LHD FG VDE+VFFQLS VKG+ PQ+G++VLV+A YNP WNA +
Sbjct: 53 EKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVK 112
Query: 205 IQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQ 264
+QTL N QPLLK+P L +A Q Q +L A Q
Sbjct: 113 VQTLSN------QPLLKSPAPPLLHVA--------ALGQKQGILGA-------------Q 145
Query: 265 PQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERER 324
PQ L+ QP + L + Q L +RF R G R DD ++ +
Sbjct: 146 PQ-LIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNRFPARGPHGRLDQGRSDDYDSKKRK 204
Query: 325 ERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRR 384
+R ++ PR + +P Y V + +++D P CD +EL+RR
Sbjct: 205 QRAGGEPWGAKK-------PRHD-----------LPPYRVHLTPYTVDSPICDFLELQRR 246
Query: 385 YQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHL 444
Y++L +PSDF +W+ AFPLS+PF L + V E E+ A D+D
Sbjct: 247 YRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQV-SSEKEAAPDAGAEPITADSDPA 305
Query: 445 YSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHW 504
YS+KV+L++SP +E+LY +D E R+ +HP + +KFL+G K ++EA+ +GG W
Sbjct: 306 YSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRK-EEEAVLVGGEW 364
Query: 505 SPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPA 564
SPSLDG DP+ DP VL++TAIRC +A TGIDLS CT+W+RFAE +Y +P P
Sbjct: 365 SPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGP-------PR 417
Query: 565 HVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEK 617
++TVV++ PDVW +PT EWE L QQ + +EA GE + E+
Sbjct: 418 RLQTVVVYLPDVWTIMPTLEEWEALC----QQKAAEAAPPTQEAQGETEPTEQ 466
Score = 192 bits (487), Expect = 2e-48
Identities = 146/473 (30%), Positives = 234/473 (49%), Gaps = 35/473 (7%)
Query: 676 KEEQKELEKSEKEED--EDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHP 733
+E Q E E +E+ D E S + E E Q+E + E P EPA+I P
Sbjct: 455 QEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPP-PLEPAVIARP 513
Query: 734 NWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSL 793
C +SL +++ R + SFEV + AELF EMLQRDFG R+YK LLSL
Sbjct: 514 G---------CVNLSLHGIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSL 563
Query: 794 PEK---EDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDK 850
PEK + EK++ +K++ K+++ +++ EPK + + G + + KED
Sbjct: 564 PEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPL----KEDG 619
Query: 851 RKDDSKDDDETEEDNNQDEYDPMEAEEAEDEE-----DDRDEEEMTKRDDKRDINRYCKE 905
EE+ + E E A D E DD +EE + + ++
Sbjct: 620 LLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASN 679
Query: 906 RPS------KDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRA 959
+ +D KE + D L+AFV+FD + CGYL +DLE IL TLG+ LS
Sbjct: 680 QSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAE 739
Query: 960 QVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVE 1019
Q K+L+++VV + C YR L + ++ + E E + GN LLP P +
Sbjct: 740 QAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPE---EVLFGNLDLLPPPGKSTKPGAAP 796
Query: 1020 -ENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKS 1078
E+ L+ +NG++++VGSLLQ+ E+ + R +E K+ LE K +E E +NK+
Sbjct: 797 TEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKT 856
Query: 1079 LSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKK 1131
L+ E++E++ L++ +E + +E Q + + + R L+ + EI V++K
Sbjct: 857 LAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEK 909
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 82.4 bits (202), Expect = 2e-15
Identities = 68/342 (19%), Positives = 161/342 (47%), Gaps = 29/342 (8%)
Query: 601 LQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKS 660
+QG+RK A + +K + +KE P +K+ K+ ++L + +K
Sbjct: 2046 VQGQRKLAKASRKLIKKRESLSKE---PAKLNKILKALQKLTRDERKLTQEEIKMTKMKR 2102
Query: 661 QLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE------------EEERKR 708
L + ++L +E+ K + KE + SEK + D K K+ +EE+
Sbjct: 2103 ALFVK-ERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMT 2161
Query: 709 QEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVS 768
+EE + R+ IL DE + G + ++ + ++ K
Sbjct: 2162 EEESKLARKHSEVILDDEE----------EGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE 2211
Query: 769 LFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPK 828
F+ +E+ + +SLL ++ +K+E +++ER++++E ++E E + +
Sbjct: 2212 KFSSQVDEVESEEHFSEEMESLL---DELEKQESLSSEEEEEREEEEEREEEEVREEEEE 2268
Query: 829 RRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEE 888
R++ + ++K+ +++E +K+ K+K+ K++ + +E+ +++ + M EE E D+ +EE
Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328
Query: 889 EMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFV 930
E +++ D + ++ + K +E+ + R+ +++ +
Sbjct: 2329 ESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSIL 2370
Score = 60.8 bits (146), Expect = 7e-09
Identities = 119/605 (19%), Positives = 246/605 (40%), Gaps = 93/605 (15%)
Query: 594 KQQLVEKLQGE--RKEADGEQDEEEKDDGEAKEIS----------TPT---------HWS 632
K++ V K++ E ++E D ++ EE E K + TP+ W
Sbjct: 1409 KERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWK 1468
Query: 633 KLDPKTMKV-NDLRKELESRALSSKGLKSQLIARLT---------KQLKVEEQKEEQKEL 682
++ +T K ++E E R L + Q +L+ K+LK EE K+ + +
Sbjct: 1469 QVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENM 1528
Query: 683 EKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKF 742
S+ +E + D + +EE R+ +E+ ++ E+R+I + +H A K
Sbjct: 1529 LSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKK- 1587
Query: 743 DCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEK 802
R ++ ++ + E A+ ++ Q + + ++ ++E + +
Sbjct: 1588 -------------RAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE 1634
Query: 803 DKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERK--------KEDKRKDD 854
K ++K+E ++ E+ + E ++RK K +K R+E K E K
Sbjct: 1635 GKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILA 1694
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
K ++ + + N D + A+E E+ E D +E + + ++ + +E K K E
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEE---KKKLAE 1751
Query: 915 KTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVL---R 971
+ + + R+ L + E EE+L L++ + K + L R
Sbjct: 1752 EEEALAWQREKL------SEEETKLAQE---EELLIQEKEKLAQHKEKMPEEEERLGRKR 1802
Query: 972 ESCFYRKLTDTSKDEENHEESESLQEDML----GNRLLLPTPTVKQESKDVEENVGLIVY 1027
E +K+ K E E L ++ + L + QE + + + ++Y
Sbjct: 1803 EQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLY 1862
Query: 1028 NGAMVDVGSLLQKLEKSEKVRAEVEQKLQL-------LEEKTDEDEKTILNLENSNKSLS 1080
N ++L S+K +V+ KL + +EEK ++++T++ +
Sbjct: 1863 N---------KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETE 1913
Query: 1081 GELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKD 1140
+L +V+ L++ QE L E M L E M + + L +D + K++ N +
Sbjct: 1914 KKLVQVEDSLAKKQEKL-AQEKMKLALEKAMVQGKKRLRGELD----IAKEEKALNLEMK 1968
Query: 1141 QKSKE 1145
+ ++E
Sbjct: 1969 RLAEE 1973
Score = 54.3 bits (129), Expect = 7e-07
Identities = 121/568 (21%), Positives = 227/568 (39%), Gaps = 91/568 (16%)
Query: 640 KVNDLRKELESRALSSKGLKSQLIARLTKQLKVE-EQKEEQKELEKSEKE-----EDEDD 693
K D+ E++ + KG K + + E +KEE+K +KS K+ + E
Sbjct: 1353 KARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERK 1412
Query: 694 DRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIV-------------HPNWAAKSG 740
K + + +EER EE+E ++ E +++ W G
Sbjct: 1413 VGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHG 1472
Query: 741 KFDCSIMSLSVLLDYRL--EDNKEHSFEVSLFAELFNEMLQRDFGVR------IYKSLLS 792
+ S + + RL E+ K H L E EMLQ D ++ +++++LS
Sbjct: 1473 ETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPE--EEMLQEDKKLKWEEWKQVWENMLS 1530
Query: 793 LPEKEDK-KEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKR 851
KE + K++++ + ++E + EE++ + E +R + K + R + E KR
Sbjct: 1531 SKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTE--EQRHIQEEHKWARIHRKRARAEKKR 1588
Query: 852 KDDSKDDDETEEDNNQDEYDPMEAEE------AEDEEDDRD-----------EEEMTKRD 894
+ + + EE Q+E + E + +DDR+ EE + +R
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRG 1648
Query: 895 DK--RDINRYCKERPSKDKEKEKT------------QMITINRDLLMAFVYFDQSHCGY- 939
+K ++ + ++R K+ EK ++ + L Q
Sbjct: 1649 EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD 1708
Query: 940 LLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDM 999
EK+L + L L + K+ ++ E KL + K EE+ + Q +
Sbjct: 1709 WQEKELAQELEELEWDMEELSWKE--EELNQEEG----KLVEEKKKLAEEEEALAWQREK 1762
Query: 1000 LGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLL-----QKLEKSEKVRAEVEQK 1054
L T ++E ++E L + M + L Q +EK K+ + E+
Sbjct: 1763 LSEE---ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERW 1819
Query: 1055 LQLLEEKTDEDEKTIL----NLENSNKSLSGE---LREVKKDLSQLQENLKISENMNLQF 1107
+ +EE T K IL NL K+L+ E L + K++L +E L S+ +Q
Sbjct: 1820 INSMEELT--KNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQV 1877
Query: 1108 ENQMNKTIRNLSTVMDEI----HTVLKK 1131
+N++ + L+ V +++ TV+KK
Sbjct: 1878 KNKLGMFNKILAQVEEKLTQEKETVIKK 1905
Score = 50.1 bits (118), Expect = 1e-05
Identities = 107/573 (18%), Positives = 237/573 (41%), Gaps = 65/573 (11%)
Query: 582 TRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKV 641
TR W+ ++++L++ EE+ +A E +P + K +K
Sbjct: 1474 TRKSWKAWKEEWEKRLLQ---------------EEEKLHQAGEKLSPEEEMLQEDKKLKW 1518
Query: 642 NDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKE-EQKELEKSEKEEDEDDDRK---- 696
+ ++ E+ LSSK + Q L+ E +E E+KE + +E++ ++ K
Sbjct: 1519 EEWKQVWENM-LSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARI 1577
Query: 697 ------SEDDKEEEERKRQEEIERQRRERRYILPDEPAIIV--------HPNWAAKSGKF 742
+E + +EERK +E E+ +E R + +E + A GKF
Sbjct: 1578 HRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Query: 743 DCSIMSL-------SVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLS--- 792
+L S + + K+ + + A ++ ++ + K++L+
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV 1697
Query: 793 --LPEKE---DKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKK 847
LP++E D +EK+ + +E + EE + +E + K ++K K + +E
Sbjct: 1698 EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 848 EDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERP 907
+ K ++ET+ ++ + + A+ +E +EEE R ++ I + K
Sbjct: 1758 WQREK---LSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQ 1814
Query: 908 SKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKD-----LEEILYTL-GLHLSRAQV 961
+++ + +T N+ +L Q EK+ E +LY L S+ Q+
Sbjct: 1815 KRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQL 1874
Query: 962 KKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEEN 1021
++ NK+ + + ++++E + + + + + K++ K +E
Sbjct: 1875 VQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEK 1934
Query: 1022 VGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTD--EDEKTILNLENSNKSL 1079
+ L + + L +L+ +++ +A + +L EEK E ++T+ E S
Sbjct: 1935 MKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSR 1994
Query: 1080 SGELREVKKDLSQ----LQENLKISENMNLQFE 1108
++ +V+++L + L+E + + E+ L E
Sbjct: 1995 QRKMTQVEQELFERKLSLEEKILLHEDRILAME 2027
Score = 46.2 bits (108), Expect = 2e-04
Identities = 114/558 (20%), Positives = 225/558 (40%), Gaps = 99/558 (17%)
Query: 596 QLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSS 655
Q+ EKL E++ + +E+ + E K + +K K + ++ LE +
Sbjct: 1890 QVEEKLTQEKETVI--KKKEKLAETEKKLVQVEDSLAKKQEKLAQ-EKMKLALEKAMVQG 1946
Query: 656 KG-LKSQL-IARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEI- 712
K L+ +L IA+ K L +E ++ ++++ E +E E ++ + + ++E+
Sbjct: 1947 KKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELF 2006
Query: 713 ERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAE 772
ER+ IL E I+ GK + + + + + + K +
Sbjct: 2007 ERKLSLEEKILLHEDRILAMEESEIAKGKLEFT-RGQRIFVQGQRKLAKASRKLIKKRES 2065
Query: 773 LFNEMLQRDFGVRIYKSLLSLPEKEDK--KEKDKKSK-------KDERKDKKEERDDETD 823
L E + + +I K+L L E K +E+ K +K K+ R ++ + D +
Sbjct: 2066 LSKEPAKLN---KILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKE 2122
Query: 824 EPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEED 883
++R +KK R +RK +K + +++ E+ ++ E ++EE
Sbjct: 2123 WDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEG 2182
Query: 884 DRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEK 943
+EEE+ +R R +R K KEK +Q+ E
Sbjct: 2183 GIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVD----------------------EV 2220
Query: 944 DLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNR 1003
+ EE H S +++ LL+++ +ES +S++EE EE E +E+ +
Sbjct: 2221 ESEE-------HFSE-EMESLLDELEKQESL-------SSEEEEEREEEEEREEEEVREE 2265
Query: 1004 LLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTD 1063
++E K+ EE E+ + + E E+K + E+K +
Sbjct: 2266 --------EEERKEEEEG--------------------EEKQVEKEEEEKKKKKKEKKKE 2297
Query: 1064 E--------DEKTILNLENSNKSLSGELRE-----VKKDLSQLQENLKISENMNLQFENQ 1110
E +EK + E +SLS E E +++++ + +E LK + LQ Q
Sbjct: 2298 EVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQ--EQ 2355
Query: 1111 MNKTIRNLSTVMDEIHTV 1128
K++R V+ + V
Sbjct: 2356 RRKSLRGRERVLSILRGV 2373
Score = 44.3 bits (103), Expect = 7e-04
Identities = 37/161 (22%), Positives = 77/161 (47%), Gaps = 28/161 (17%)
Query: 566 VETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDE-EEKDDGEAKE 624
VE+ F ++ L + E+LS +++ E+ + E +E E++E +E+++GE K+
Sbjct: 2220 VESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQ 2279
Query: 625 ISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEK 684
+ K K K +++++ E V E+KEE E+
Sbjct: 2280 VEKEEEEKKKKKKEKKKEEVQEKEE----------------------VFEEKEEIMSEEE 2317
Query: 685 SEKEEDEDDDRKS-----EDDKEEEERKRQEEIERQRRERR 720
+E DE+++ +S E D+E+E K++++ + Q + R+
Sbjct: 2318 TESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRK 2358
Score = 40.4 bits (93), Expect = 0.010
Identities = 132/675 (19%), Positives = 262/675 (38%), Gaps = 132/675 (19%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTM--K 640
R E + +G K V+ + ++ E ++ E+ D + KE++ + D + + K
Sbjct: 1674 REEEKLAKKGGKLAEVKNILAQKVEELPQR--EQNLDWQEKELAQELEELEWDMEELSWK 1731
Query: 641 VNDLRKELESRALSSKGL--KSQLIARLTKQLKVEEQK-EEQKELEKSEKEEDEDDDRKS 697
+L +E K L + + +A ++L EE K +++EL EKE+ K
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 698 EDDKEEEERKRQEEIER-----QRRER-----------RYILPDEPAIIVHPNWAAKSGK 741
+++E RKR++ IE+ Q+RER + IL + + A+ +
Sbjct: 1792 PEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851
Query: 742 FDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEML--------QRDFGVRIYKSLLSL 793
+ RL +K+ +V +FN++L Q V K L+
Sbjct: 1852 KLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAE 1911
Query: 794 PEKEDKKEKDKKSKKDER-KDKKEERDDETDEPKPKRRKSGDDKDKKEDRD-----ERKK 847
EK+ + +D +KK E+ +K + E + K+R G+ KE++ +R
Sbjct: 1912 TEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLA 1971
Query: 848 EDKRK----DDSKDDDETEEDNNQDEYDPMEAEEAEDE---------EDDR----DEEEM 890
E+K + ++ ET E + Q + +E E E + +DR +E E+
Sbjct: 1972 EEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEI 2031
Query: 891 TK----------------RDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQ 934
K R + + K+R S KE K I L A +
Sbjct: 2032 AKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKI------LKALQKLTR 2085
Query: 935 SHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESES 994
L +++++ L + ++ +K+ ++E F K ++ +KDE+ +
Sbjct: 2086 DE-RKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQR 2144
Query: 995 LQEDMLGNRLLLPTPTVKQESK----------DVEENVGLIVYN---------------- 1028
+ + + ++ESK D EE G+
Sbjct: 2145 KLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAK 2204
Query: 1029 ---------GAMVD-----------VGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKT 1068
+ VD + SLL +LEK E + +E E++ + EE+ E+E+
Sbjct: 2205 RGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEERE--EEEEREEEEV 2262
Query: 1069 ILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTV 1128
E + GE ++V+K+ + ++ K + +Q + + +M E T
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQ---EKEEVFEEKEEIMSEEET- 2318
Query: 1129 LKKDNVKNEDKDQKS 1143
+++ +E+++++S
Sbjct: 2319 ---ESLSDEEEEEES 2330
Score = 33.9 bits (76), Expect = 0.91
Identities = 82/398 (20%), Positives = 161/398 (40%), Gaps = 64/398 (16%)
Query: 799 KKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDD 858
K K K + ++R ++EE+ + E + S +++ +ED+ + +E K+ ++
Sbjct: 1476 KSWKAWKEEWEKRLLQEEEKLHQAGE-----KLSPEEEMLQEDKKLKWEEWKQVWENMLS 1530
Query: 859 DETEEDNNQDEYDPMEAEEAEDEEDDRDE---EEMTKRDDKRDINRYCKERPSKDKEK-- 913
+++E +DE + EE E +++++ EE ++ R ++R +K++
Sbjct: 1531 SKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590
Query: 914 --------------EKTQMITINRDLLMAFVYFDQSHC------GYLLEKDLEEILYTLG 953
E+ Q+ R L A+V Q G +K EE L G
Sbjct: 1591 EERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQK--EETLAQRG 1648
Query: 954 LHLS---------RAQVKKLLNKVVLRESCFYRK----------LTDTSKDEENHEESES 994
LS R ++ K KV E +K L ++ E++
Sbjct: 1649 EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD 1708
Query: 995 LQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQK 1054
QE L L +++ S EE L G +V+ +KL + E+ A +K
Sbjct: 1709 WQEKELAQELEELEWDMEELSWKEEE---LNQEEGKLVEE---KKKLAEEEEALAWQREK 1762
Query: 1055 LQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNL-----QFEN 1109
L E K ++E+ ++ + ++ E ++ L + +E L I + M L ++ N
Sbjct: 1763 LSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL-IEKKMKLAQKRERWIN 1821
Query: 1110 QMNKTIRNLSTVMDEIHTVLKKDNVKNE-DKDQKSKEN 1146
M + +N + + + +K N+ E +K + KEN
Sbjct: 1822 SMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKEN 1859
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 80.1 bits (196), Expect = 1e-14
Identities = 68/288 (23%), Positives = 137/288 (47%), Gaps = 38/288 (13%)
Query: 629 THWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKE 688
T ++K D K + +K ++ + SK K +K++K +K+++K K K+
Sbjct: 281 TKYTKKDTK----KNAKKSSDAESEDSKDAKKD-----SKKVKKNVKKDDKK---KDVKK 328
Query: 689 EDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMS 748
+ E D +S D K+E + ++++ + ++ +++ P + AK + D +
Sbjct: 329 DTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLK 388
Query: 749 LSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKK 808
+ D + +D K+ +F +EL ++ Q+D EK+DKK+ +KK
Sbjct: 389 KASKNDDKKKDAKKITFSTDSESELESKESQKD-------------EKKDKKDSKTDNKK 435
Query: 809 DERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQD 868
+ D EE D EPK +K KD+K+ + + KK+DK+KD K+ + TE +++
Sbjct: 436 SVKND--EESTDADSEPKGDSKKG--KKDEKKGKKDSKKDDKKKDAKKNAESTEMESDL- 490
Query: 869 EYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKT 916
E + ++ E++ +K+D K+D + + ++ E KT
Sbjct: 491 --------ELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKT 530
Score = 61.6 bits (148), Expect = 4e-09
Identities = 62/297 (20%), Positives = 125/297 (42%), Gaps = 27/297 (9%)
Query: 649 ESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKR 708
ES+ + + K Q A T E ++ +K SE + + + + ++++K
Sbjct: 143 ESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKD 202
Query: 709 QEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVS 768
+ ++ E + + + + CS SL+V + + + S
Sbjct: 203 SKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFD 262
Query: 769 LFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKD------KKSKKDERKDKKE-ERDDE 821
+ +++ +++ ++ K +K KK D K +KKD +K KK ++DD+
Sbjct: 263 AWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDK 322
Query: 822 TDEPKPKRR----KSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEE 877
+ K +SGD KD+++D + KK+ K+ D KD + E + + D +A
Sbjct: 323 KKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDA-- 380
Query: 878 AEDEEDDRDEEEMTKRDDKR----------DINRYCKERPS-KDKEKEKTQMITINR 923
D R+ ++ +K DDK+ D + + S KD++K+K T N+
Sbjct: 381 ---RNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNK 434
Score = 56.6 bits (135), Expect = 1e-07
Identities = 82/371 (22%), Positives = 147/371 (39%), Gaps = 54/371 (14%)
Query: 786 IYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPK-----RRKSGDDKDKKE 840
+Y S L + E KK KD+K +KD K++ P+ K + K ++ DK
Sbjct: 103 LYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTP 162
Query: 841 DRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDR---DEEEMTKRDDKR 897
+ + E +K S + E N++ ++ +D ++ + E TK + K+
Sbjct: 163 LKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKK 222
Query: 898 DINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLS 957
D+ R + S D E ++N D LM + + D E I + L
Sbjct: 223 DLKR---SKTSNDPISEICSENSLNVDFLM-----------LVGQSDDESINFDAWLRNY 268
Query: 958 RAQVKKLLNKVVLRESCFYRKLT--DTSKDEENHEESESLQEDMLGNRLLLPTPTVKQES 1015
K S Y K T DT K+ + ++ES ED + K++S
Sbjct: 269 SQNNSK-------NYSLKYTKYTKKDTKKNAKKSSDAES--ED---------SKDAKKDS 310
Query: 1016 KDVEENVGL-IVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLEN 1074
K V++NV D S + S+ R + ++ + L K D+ +K
Sbjct: 311 KKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKL--KKDDKKKDTKKYPE 368
Query: 1075 SNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNV 1134
S + SG+ ++ + D L+ K S+N + K + ++ D + K++
Sbjct: 369 STDTESGDAKDARNDSRNLK---KASKN------DDKKKDAKKITFSTDSESELESKESQ 419
Query: 1135 KNEDKDQKSKE 1145
K+E KD+K +
Sbjct: 420 KDEKKDKKDSK 430
Score = 48.5 bits (114), Expect = 4e-05
Identities = 61/275 (22%), Positives = 115/275 (41%), Gaps = 47/275 (17%)
Query: 600 KLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLK 659
K ++K+ + + + + G++K+ T K D K +K +D +K+ + S+
Sbjct: 318 KKDDKKKDVKKDTESTDAESGDSKDERKDT---KKDKKKLKKDDKKKDTKKYPESTD--- 371
Query: 660 SQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRK----SEDDKEEEERKRQEEIERQ 715
T+ ++ + + + L+K+ K +D+ D K S D + E E K ++ E++
Sbjct: 372 -------TESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKK 424
Query: 716 RRE------RRYILPDEPAIIV--HPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEV 767
++ ++ + DE + P +K GK D D + +D K+++
Sbjct: 425 DKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAEST 484
Query: 768 SLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEP-- 825
+ ++L L++D ++KK K KKD RKD E D E DE
Sbjct: 485 EMESDL---ELKKD-----------KKHSKEKKGSKKDIKKDARKD-TESTDAEFDESSK 529
Query: 826 ---KPKRRKSGDDKDKKEDRDERKKEDKRKDDSKD 857
K + G D + +E K K+K D D
Sbjct: 530 TGFKTSTKIKGSDTESEESL--YKPGAKKKIDESD 562
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/331 (18%), Positives = 133/331 (40%), Gaps = 25/331 (7%)
Query: 605 RKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQL-- 662
+K A D E +D +AK+ S K K K D++K+ ES S K +
Sbjct: 289 KKNAKKSSDAESEDSKDAKKDSKKV--KKNVKKDDKKKDVKKDTESTDAESGDSKDERKD 346
Query: 663 IARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYI 722
+ K+LK +++K++ K+ +S E D D + ++ + ++ ++ ++ +
Sbjct: 347 TKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFS 406
Query: 723 LPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDF 782
E + + +S K + S + + N E S + + ++ ++D
Sbjct: 407 TDSESELE-----SKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKD- 460
Query: 783 GVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDR 842
+ K+D K+KD K K E + + + + + D+ K +K KK+ R
Sbjct: 461 -----EKKGKKDSKKDDKKKDAK-KNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDAR 514
Query: 843 DERKKEDKRKDDSKDD--------DETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRD 894
+ + D D+S ++ ++ + Y P ++ ++ + +M +
Sbjct: 515 KDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLE 574
Query: 895 DKRDINRYCKERPSKDK-EKEKTQMITINRD 924
KR K+ +K EK T + +R+
Sbjct: 575 SKRGFRMSSKKTTFNEKGEKASTGRVPPSRE 605
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 79.0 bits (193), Expect = 2e-14
Identities = 109/516 (21%), Positives = 218/516 (42%), Gaps = 84/516 (16%)
Query: 599 EKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLR-KELESRALSSKG 657
E+ E++E EQ+E+ ++ E W + K M+ + + ++ E R
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ--EKQMREQEQKMRDQEERMWEQDE 404
Query: 658 LKSQLIARLTKQLK----VEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIE 713
+ R+ +Q K VE+ +EE+K E+ +K D+++ + E+ E E+K +EE E
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 714 RQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAEL 773
R + + E + W + ++ RL + KE +E E
Sbjct: 465 TMREQEEKMQKQEENM-----WEQEEKEWQ----------QQRLPEQKEKLWEQEKMQEQ 509
Query: 774 FNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSG 833
++ +++ +R D++E + KK R++K E++D+ E + K R
Sbjct: 510 EEKIWEQEEKIR------------DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR--- 554
Query: 834 DDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKR 893
D + K D++ER ++ ++ + K D+ E+ ++ E + E+EE R++EE +
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 894 DDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLG 953
+++ +E+ K E+E+ +Q + E+ + E
Sbjct: 615 QEEK-----MQEQEEKMWEQEEKMQ--------------EQEEKMWEQEEKMWE------ 649
Query: 954 LHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQ 1013
Q +K+ + L E KL + K +E + E QE+ + + + T +Q
Sbjct: 650 ------QEEKMWEQQRLPEQ--KEKLWEHEKMQEQEKMQE--QEEKIWEQEKMEKKTQEQ 699
Query: 1014 ESKDVEENVGLIVYNGAMVDVGSLLQ---KLEKSEKVRAEVEQKLQLLEEKTDEDEKTIL 1070
E K ++ M + S+ + K+ + E++ E E+K+Q EEK E E+ +
Sbjct: 700 EKKTWDQE--------KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Query: 1071 NLENSNKSLSGELREVKKDLSQLQENLKISENMNLQ 1106
E ++ E ++ L + +E L E M Q
Sbjct: 752 EQEEKMWEQEEKMWEQQR-LPEQKEKLWEHEKMQEQ 786
Score = 71.2 bits (173), Expect = 5e-12
Identities = 113/586 (19%), Positives = 245/586 (41%), Gaps = 109/586 (18%)
Query: 600 KLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKEL----ESRALSS 655
+LQ + A+ E+ E + + KE+ +K ++ N L++E+ E
Sbjct: 229 ELQEKLPLAESEKSEIQLN---VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 285
Query: 656 KGLKSQLIARLTKQLKVEEQ------------------KEEQKELEKSEKE-EDEDDDRK 696
K ++ Q ++ ++ EQ +E++KEL + EKE ++ + R+
Sbjct: 286 KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345
Query: 697 SEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYR 756
E+ +E+E K E+ E+ R + + E + W + + + +
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL-----WEQEKQMRE---------QEQK 391
Query: 757 LEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKE 816
+ D +E +E E ++ ++++ + + E++ +E++KK++ E K ++E
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQ--EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449
Query: 817 ERDDETDE---PKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPM 873
ER E ++ + + + ++K +K++ + ++E+K + ++ E+ Q++
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 509
Query: 874 EAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFD 933
E + E EE RD+EEM ++ K + R K R +D+ E+ + + + +D
Sbjct: 510 EEKIWEQEEKIRDQEEMWGQEKK--MWRQEKMREQEDQMWEQEEKMRDQEQKM-----WD 562
Query: 934 QSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLN-KVVLRESCFYRKLTDTSKDEEN--HE 990
Q +EK +E Q KK + + +RE R+ ++EE E
Sbjct: 563 QEE---RMEKKTQE------------QEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 991 ESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAE 1050
+ E +QE +QE K E+ +K+++ E+ E
Sbjct: 608 QEEKMQEQ--------EEKMQEQEEKMWEQE-----------------EKMQEQEEKMWE 642
Query: 1051 VEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQ 1110
E+K+ EEK E ++ E K E + ++ + + +E + E M + + Q
Sbjct: 643 QEEKMWEQEEKMWEQQRL---PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 1111 MNKT-----------IRNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
KT +R M E ++++ K +++++K +E
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Score = 70.9 bits (172), Expect = 7e-12
Identities = 98/535 (18%), Positives = 234/535 (43%), Gaps = 56/535 (10%)
Query: 613 DEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKV 672
+E +K + E +E P S+ + V +L+++LE +K L Q+ T Q ++
Sbjct: 221 EELKKKNAELQE-KLPLAESEKSEIQLNVKELKRKLER----AKFLLPQVQTN-TLQEEM 274
Query: 673 EEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVH 732
Q+EE +E EK ++++E R+ E +E+E + R++E + R+E+R L ++ +
Sbjct: 275 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR--LREQEKELRE 332
Query: 733 PNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLS 792
+ L + KE + E +M +++ +R + +
Sbjct: 333 Q--------------------EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMW 372
Query: 793 LPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRK 852
E+ +++ + +++++ +EER E DE ++ + +++K ++ E+ +E+K+
Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432
Query: 853 DDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKE 912
+ + +E+ Q+E E + E EEE T R+ + + + + ++++
Sbjct: 433 QEQEKKTRDQEEKMQEE------ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 913 KEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRE 972
+ + Q + ++ L ++Q EK E+ Q KK+ + +RE
Sbjct: 487 EWQQQRLPEQKEKL-----WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 973 SCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESK--DVEENVGLIVYNGA 1030
+ E E+ ++ M + T +QE K D EE +
Sbjct: 542 --------QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM------RE 587
Query: 1031 MVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDL 1090
+ +K+ + E++ E E+K+Q EEK E E+ + E + ++ E ++ +
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 1091 SQLQENLKISENMNLQFENQM-NKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSK 1144
+ +E + + + Q E ++ ++ + ++ + +++ ++ + ++Q+ K
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Score = 65.5 bits (158), Expect = 3e-10
Identities = 90/541 (16%), Positives = 235/541 (43%), Gaps = 46/541 (8%)
Query: 599 EKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGL 658
E+ +++E EQDE ++ E W +++ + +E ++R K
Sbjct: 389 EQKMRDQEERMWEQDERLREKEERMR-EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 659 KSQLIARLTKQLKVEEQ--KEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQR 716
+ + I K+++ EE+ +E++++++K E+ E ++++ + + E++++ E E+ +
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 717 RERRYILPDEPAIIVHPN-WAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFN 775
+ I E I W + + M + E+ + E
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 776 EMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDER--KDKKEERDDETDEPKPKRRKSG 833
E ++ + + + E+E +E++KK +++E ++++E+ ++ ++ + + K
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW 627
Query: 834 DDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPM-EAEEAEDEEDDRDEEEMTK 892
+ ++K ++++E+ E + K +++ E+ ++ + + E E+ +++E +++EE
Sbjct: 628 EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIW 687
Query: 893 RDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTL 952
+K + +E+ + D+EK + + R+ M ++ EE++
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM---------------REEEEMM--- 729
Query: 953 GLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVK 1012
R Q +K+ + K+ + ++ EE QE+ + + LP K
Sbjct: 730 -----REQEEKMQEQ--------EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Query: 1013 -QESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILN 1071
E + ++E + M D ++ E EK+R + E+K++ EEK E+ +
Sbjct: 777 LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE--EKMRGQ-EEKMRGQEEKMWGQEEKMWG 833
Query: 1072 LE----NSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHT 1127
E + + G+ ++++ + +E ++ E E +M + + ++I+
Sbjct: 834 QEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYC 893
Query: 1128 V 1128
V
Sbjct: 894 V 894
Score = 62.8 bits (151), Expect = 2e-09
Identities = 58/344 (16%), Positives = 164/344 (47%), Gaps = 23/344 (6%)
Query: 586 WETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLR 645
WE + ++QQ + + + + E + Q++EEK + ++I + K + +R
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 646 KELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK---E 702
++ + + ++ Q ++ ++E++ +EQ++ ++E+ +++R E +K E
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 703 EEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKE 762
EEE R++E + Q +E + +E + K + ++ + +E
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ--------EEKMWEQEE 652
Query: 763 HSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEK-DKKSKKDERKDKKEERDDE 821
+E E ++ + + ++ + + EK ++EK +KK+++ E+K +E+ E
Sbjct: 653 KMWEQQRLPEQKEKLWEHE-KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711
Query: 822 TDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYD---------P 872
+ + + +K ++++ +++E+ +E + K ++++ E++ E + P
Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 873 MEAEEAEDEEDDRDEEEMTKRDDK-RDINRYCKERPSKDKEKEK 915
+ E+ + E +++E++ ++++K RD + + K + +E+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815
Score = 62.0 bits (149), Expect = 3e-09
Identities = 61/328 (18%), Positives = 157/328 (47%), Gaps = 19/328 (5%)
Query: 598 VEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKG 657
VEK++ E+K Q++E+K + +++ + + K + + +E E + +
Sbjct: 423 VEKMREEKKM----QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478
Query: 658 LKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE--DDDRKSEDDKE---EEERKRQEEI 712
+ + +Q ++ EQKE+ E EK +++E++ + + K D +E +E++ ++E
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 538
Query: 713 ERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAE 772
R++ ++ + ++ W + + + + + D +E E E
Sbjct: 539 MREQEDQMWEQEEKMRDQEQKMWDQEE-----RMEKKTQEQEKKTWDQEEKMREEERMRE 593
Query: 773 LFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKS 832
+M + + +R + + E++ +++++K +++E+ ++EE+ E +E ++ +
Sbjct: 594 REKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEK 653
Query: 833 GDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAE----DEEDDRDEE 888
++ + ++ E+ E ++ + + E EE + E + +E E D+E R+EE
Sbjct: 654 MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 889 EMTKRDDK-RDINRYCKERPSKDKEKEK 915
M +R+ K R+ +E+ K +E+E+
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEE 741
Score = 56.6 bits (135), Expect = 1e-07
Identities = 57/311 (18%), Positives = 150/311 (48%), Gaps = 13/311 (4%)
Query: 591 RGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELES 650
R K + E E++E +Q+++ D E E T + + KT + +E E
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT----QEQEKKTWDQEEKMREEER 590
Query: 651 RALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQE 710
K ++ + ++ K++EQ+E+ +E E+ E++E + E E+EE+ ++
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 711 EIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSL--SVLLDYRLEDNKEHSFEVS 768
E + ++R LP++ + + K + ++ + ++ ++ +++
Sbjct: 651 EEKMWEQQR---LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707
Query: 769 LFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPK 828
E M +R+ +R + ++ E++ +++++K +++E ++EE+ E +E +
Sbjct: 708 KMREE-ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE 766
Query: 829 RRKSGDDKDKKEDRDERKKEDK-RKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDR-- 885
+++ + K+K + ++ ++++K + + K D+ E+ Q+E + E+ +E+
Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826
Query: 886 DEEEMTKRDDK 896
EE+M +++K
Sbjct: 827 QEEKMWGQEEK 837
Score = 52.4 bits (124), Expect = 2e-06
Identities = 66/339 (19%), Positives = 138/339 (40%), Gaps = 41/339 (12%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
R E R K + E++ E++E EQ EE+ + E K + + K +
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQ-EEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 643 DLRKELESRALSSKGLKSQLIA-----RLTKQLKVEEQKEEQKELEKSEKEEDEDDDR-- 695
+ E E + + L Q ++ +Q K++EQ+E+ E EK EK+ E + +
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704
Query: 696 -----KSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPN--WAAKSGKFDCSIMS 748
+ E+ E E+K +EE E R + + E + W + ++
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE---QE 761
Query: 749 LSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKK 808
+ RL + KE +E +E +Q EK ++E+ + ++
Sbjct: 762 EKMWEQQRLPEQKEKLWE--------HEKMQEQ-------------EKIWEQEEKMRDQE 800
Query: 809 DERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQD 868
++ + ++E+ + ++ + + K ++K ++E+ + K +++ E+ Q+
Sbjct: 801 EKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQE 860
Query: 869 EYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERP 907
E + E+ +E+ E+E R + I YC P
Sbjct: 861 EKMREQEEKMRGQEEKMREQEEKMRGQEEKI--YCVGSP 897
Score = 34.7 bits (78), Expect = 0.54
Identities = 29/136 (21%), Positives = 65/136 (47%), Gaps = 13/136 (9%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRAL 653
K++L E + + +E EQ+E+ +D E K+ + K+ +++ +
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMRDQEE-----------KMRGQEEKMRGQEEKMRGQEE 822
Query: 654 SSKGLKSQLIARLTKQLKVEEQK--EEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEE 711
G + ++ + K EE+ +E+K EK + +E++ +++ + +EE+ + QEE
Sbjct: 823 KMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEE 882
Query: 712 IERQRRERRYILPDEP 727
R + E+ Y + P
Sbjct: 883 KMRGQEEKIYCVGSPP 898
Score = 30.8 bits (68), Expect = 7.7
Identities = 32/169 (18%), Positives = 71/169 (42%), Gaps = 21/169 (12%)
Query: 981 DTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIV-------YNGAMVD 1033
+T +EE +++ LQE + P + E +++ NV + + V
Sbjct: 216 NTITNEELKKKNAELQEKL---------PLAESEKSEIQLNVKELKRKLERAKFLLPQVQ 266
Query: 1034 VGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQL 1093
+L +++ + E+ E E+K++ EEK E+ + E + ++ +K L +
Sbjct: 267 TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQ 326
Query: 1094 QENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQK 1142
++ L+ E E + K +R M E + + K ++++K
Sbjct: 327 EKELREQEK-----ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 79.0 bits (193), Expect = 2e-14
Identities = 83/353 (23%), Positives = 159/353 (45%), Gaps = 40/353 (11%)
Query: 585 EWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDG----EAKEISTPT--------HWS 632
E E L G K Q +K + E + + + D G ++ TPT
Sbjct: 255 EKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314
Query: 633 KLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDED 692
K D K K KE E + SK + L K LK EE++++++E E+ ++ E+ +
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAK-LKEEEERQKREEEERIKRLEELE 373
Query: 693 DDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKF---------D 743
RK E+ E+E+R+R+++ E++R+ER L E ++ A++
Sbjct: 374 AKRKEEERLEQEKRERKKQKEKERKER---LKKEGKLLTKSQREARARAEATLKLLQAQG 430
Query: 744 CSIMSLSVLLDYR--LEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKE 801
+ S L R ED K L ++ +E ++ V + + +PEKE+
Sbjct: 431 VEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQ--GVPEKEETPP 488
Query: 802 KDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDET 861
+ ++++ +D + D E + K +K E ++ ++E++ +++ ++D+E+
Sbjct: 489 PVEPEEEEDTEDAGLD-DWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEES 547
Query: 862 EEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
EE+ E EE E E + DEE+ K D++D + ++PSK+ +
Sbjct: 548 EEE---------EEEEGESEGSEGDEED-EKVSDEKDSGKTLDKKPSKEMSSD 590
Score = 75.9 bits (185), Expect = 2e-13
Identities = 123/532 (23%), Positives = 217/532 (40%), Gaps = 79/532 (14%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDD-GEAKEISTPTHWSKLDPKTMKVNDLRKELES-- 650
K+Q +K +G++K+ +QD +E D E +E+S K D +T+ V E
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFT 92
Query: 651 ----RALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDD------------ 694
+ KG K +++L+ ++ K ++ K E DDD
Sbjct: 93 SKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKG 152
Query: 695 -----RKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSL 749
K D EE+E ++ ER R DE + K + + ++
Sbjct: 153 KAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212
Query: 750 SVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKD 809
++ + SF++ A+ E +R+ R + KE KE+ + KKD
Sbjct: 213 E-----SGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKE--KEELETGKKD 265
Query: 810 ERKDKKEER--DDETDEPK--------PKRRKSGDDKDKKEDR---DERKKEDKRKDDSK 856
+ K K+ +R ++ET + K P + + ED D++KK+ K+K K
Sbjct: 266 QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEK 325
Query: 857 DDDETEEDNNQDEYDPMEAEEA------EDEEDDRDEEEMTKRDDKRDINRYCKERPSKD 910
++ E E+ + +EA E+E R+EEE KR ++ + R +ER ++
Sbjct: 326 EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQE 385
Query: 911 KEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEE--ILYTLGLHLSRAQVKKLLNKV 968
K + K Q ++ L G LL K E L L +AQ ++ +K
Sbjct: 386 KRERKKQKEKERKERL--------KKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKD 437
Query: 969 VL-RESCFY--RKLTDTSKDEENHEESESLQ--------EDMLGNRLLLPTPTVKQESKD 1017
L ++ Y +K + E+ E SES++ E + + P P +E +D
Sbjct: 438 SLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEED 497
Query: 1018 VEENVGLIVYNGAMVDVGSLLQKLEKSE--KVRAEVEQKLQLLEEKTDEDEK 1067
E+ GL + D ++ EK E KV EV++ + EE+ +E+E+
Sbjct: 498 TED-AGLDDWEAMASD-----EETEKVEGNKVHIEVKENPEEEEEEEEEEEE 543
Score = 62.0 bits (149), Expect = 3e-09
Identities = 64/305 (20%), Positives = 139/305 (45%), Gaps = 43/305 (14%)
Query: 602 QGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQ 661
+G++K+ D ++ + EK++ E ++ P SK K M+ + +L+ K + +
Sbjct: 310 EGDKKKKDKKKKKGEKEEKEKEKKKGP---SKATVKAMQ--EALAKLKEEEERQKREEEE 364
Query: 662 LIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRY 721
I RL ++L+ + ++EE+ E EK E+++ ++ +RK KE + + + R R E
Sbjct: 365 RIKRL-EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATL 423
Query: 722 ILPDEPAIIV---------HPNWAAKSGK-----FDCSIMSLSVLLDYRLE--------- 758
L + V P + K K + +S S+ L +E
Sbjct: 424 KLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEK 483
Query: 759 ---------DNKEHSFEVSLF---AELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKS 806
+ +E + + L A +E ++ G +++ + PE+E+++E++++
Sbjct: 484 EETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEE 543
Query: 807 KKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD--SKDDDETEED 864
++ ++++EE + E E + K D+KD + D++ ++ D DDD T+E+
Sbjct: 544 DEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEE 603
Query: 865 NNQDE 869
D+
Sbjct: 604 RAYDK 608
Score = 43.5 bits (101), Expect = 0.001
Identities = 69/360 (19%), Positives = 140/360 (38%), Gaps = 55/360 (15%)
Query: 804 KKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDD--DET 861
KK K K++ D + + + + +++ ++ + ++KKE K++D +DD E
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 862 EEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCK---------ERPSKDKE 912
EE + + + + E + + +EEE T +D K+ + K E KD +
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSK 122
Query: 913 KEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRE 972
+KT + + + G + D ++ ++ K ++
Sbjct: 123 SKKTAKPKV------------EMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN 170
Query: 973 SCFYRKLTDTSKDEENHEESESLQEDMLG---NRLLLPTPTVK--QESKDVEENVGLIVY 1027
S ++ + + E+ +ES+ + G N+ P P ++ E D + +
Sbjct: 171 SKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQ 230
Query: 1028 NGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVK 1087
A +K E+ K R E + KL+ L+EK EL K
Sbjct: 231 KKA--------EKKERERKKRDEEKAKLRKLKEKE-------------------ELETGK 263
Query: 1088 KDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKENG 1147
KD S+ +E+ + E ++ + ++ + S E T + DN ++ K K K+ G
Sbjct: 264 KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG 323
Score = 38.1 bits (87), Expect = 0.048
Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 36/148 (24%)
Query: 575 DVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKL 634
D W + + E E + V++ E +E + E++E+E+ + E +E
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEE---------- 553
Query: 635 DPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKS-EKEEDEDD 693
E + S+G + + KV ++K+ K L+K KE D
Sbjct: 554 --------------EGESEGSEGDE--------EDEKVSDEKDSGKTLDKKPSKEMSSDS 591
Query: 694 DRKSEDDKEEEER---KRQEEIERQRRE 718
+ S+DD+ +EER K + IE++R E
Sbjct: 592 EYDSDDDRTKEERAYDKAKRRIEKRRLE 619
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 78.2 bits (191), Expect = 4e-14
Identities = 69/333 (20%), Positives = 146/333 (43%), Gaps = 39/333 (11%)
Query: 606 KEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIAR 665
K+ADG+ E + KE + + +T + + R+E + + + Q
Sbjct: 47 KDADGDDRERNRQ----KERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE 102
Query: 666 LTKQLKVEEQKEEQKELEKS-EKEEDEDDDRKSE-------DDKEEEERKRQEEIERQRR 717
++ + + +++ Q+E E++ +KE + + +R+ E D + E ER+R E ER+R+
Sbjct: 103 KERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ 162
Query: 718 ERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEM 777
R E N + + E N++ E E N+
Sbjct: 163 TDR-----ERQRQTERNRQKERER----------------EKNRQERRERERQREKENKT 201
Query: 778 LQR--DFGVRIYKSLLSLPEKEDKK----EKDKKSKKDERKDKKEERDDETDEPKPKRRK 831
R + G + + E E K+ E+D++ K + ++K+ ER+ ++ + ++
Sbjct: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKE 261
Query: 832 SGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMT 891
++D+ DRD R+KE +R+ D K TE D + + E + E +R E
Sbjct: 262 RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321
Query: 892 KRDDKRDINRYCKERPSKDKEKEKTQMITINRD 924
+R+ +R+ R + K++E+++ + ++R+
Sbjct: 322 ERERERERQRETERDREKERERKRKRQTEMDRE 354
Score = 77.0 bits (188), Expect = 9e-14
Identities = 62/331 (18%), Positives = 147/331 (44%), Gaps = 36/331 (10%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRAL 653
K++ +K + E +GE+ + + DG+ + + D KE E +
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRER--------------ERQRDAEKERERQ-- 162
Query: 654 SSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEE-ERKRQEEI 712
+ + + Q K+ + E+ ++E++E E+ ++E++ +DR SE +E E ER+ + E
Sbjct: 163 TDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET 222
Query: 713 ERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAE 772
ER+R+ R + K+ + + E +KE E +
Sbjct: 223 ERKRQTDR-----------ERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
Query: 773 LFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKS 832
+R+ + + ++E +++++++ +++ +++ +R+ E + + + R+
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Query: 833 GDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEY--------DPMEAEEAEDEEDD 884
++D++++R+ ++K D ++ E Q E D A E E+ E D
Sbjct: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Query: 885 RDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
RD + +R+ + + +R + K +E+EK
Sbjct: 392 RDRDRQKERERQTEKDRDGQRETEKQREREK 422
Score = 77.0 bits (188), Expect = 9e-14
Identities = 61/323 (18%), Positives = 151/323 (46%), Gaps = 28/323 (8%)
Query: 602 QGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQ 661
+G ++ DG+++ E + D E KE T D + + + ++ E ++ + +
Sbjct: 137 RGRDRQTDGQRERERQRDAE-KERERQT-----DRERQRQTERNRQKEREREKNRQERRE 190
Query: 662 LIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEE-----ERKRQEEIERQR 716
+ K+ K E++ E+ + E+E + + +RK + D+E + ER+R+++ ER+R
Sbjct: 191 RERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
Query: 717 RERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNE 776
R D+ + D D + + E E E E
Sbjct: 251 ASERETERDKE----RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
Query: 777 MLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERD----DETDEPKPKRRKS 832
+ + E+E ++E++++ +++ +D+++ER+ +T+ + + R++
Sbjct: 307 RERE-------RERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359
Query: 833 GDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTK 892
G + ++ +R+ ++ ++ + +++ +E E D ++D E + +D + R+ E+ +
Sbjct: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419
Query: 893 RDDKRDINRYCKERPSKDKEKEK 915
R+ R+ R +ER +++EK+K
Sbjct: 420 REKDRESER-GRER-GREREKQK 440
Score = 77.0 bits (188), Expect = 9e-14
Identities = 70/324 (21%), Positives = 138/324 (42%), Gaps = 49/324 (15%)
Query: 591 RGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELES 650
R ++Q Q ER+ Q+ E++ KE T S+ + + + E E
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETER 224
Query: 651 RALSSKGLKSQLIARLTKQLKVEEQKEEQKELEK-SEKEEDEDDDRKSEDDKEEEERKRQ 709
K Q +Q K E ++E+Q E E+ SE+E + D +R+ E D++ + +RQ
Sbjct: 225 --------KRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
Query: 710 EEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSL 769
+E ERQ +R + D E +E E
Sbjct: 277 KERERQTDRKRQRRTER---------------------------DRETERKRERQRERER 309
Query: 770 FAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEER----------D 819
E N +R+ + E++ +KE+++K K+ D++ R +
Sbjct: 310 ERER-NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE 368
Query: 820 DETDEPKPKRRKSGDDKDKKE-DRD-ERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEE 877
E + + + R+S +++++E DRD +R+KE +R+ + D + E + ++ E+E
Sbjct: 369 RERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
Query: 878 AEDEEDDRDEEEMTKRDDKRDINR 901
+ +R++++ +RD +R +R
Sbjct: 429 GRERGREREKQKGRERDRERQTDR 452
Score = 62.8 bits (151), Expect = 2e-09
Identities = 60/301 (19%), Positives = 129/301 (42%), Gaps = 40/301 (13%)
Query: 624 EISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELE 683
E++ P +S+ P + + + R+ L + G + + ++ + E+++ E++
Sbjct: 19 EVTIPLDFSRRRPGSQE-SPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDR 77
Query: 684 KSEKEEDEDDDRKSE-------DDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWA 736
K E+ ++D RK + D ++E ER+ E +RQR + R +
Sbjct: 78 KRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER 137
Query: 737 AKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEK 796
+ + D + E ++ E + E ++ E+
Sbjct: 138 GRDRQ-----------TDGQRERERQRDAEKERERQTDRERQRQ-------------TER 173
Query: 797 EDKKEKDKKSKKDERKDKKEERDDE--TDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
+KE++++ + ER++++ +R+ E T++ +R + + + + E ERK++ R+ D
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
+ E E + E E A + E +RD+E +RD RD +R KER + K
Sbjct: 234 RQRKTEREREKQ------AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKR 287
Query: 915 K 915
+
Sbjct: 288 Q 288
Score = 50.8 bits (120), Expect = 7e-06
Identities = 25/53 (47%), Positives = 33/53 (62%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R D+ RK +R RERERER R+R+R +R+R RER +RE ER + R
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
Score = 50.1 bits (118), Expect = 1e-05
Identities = 27/64 (42%), Positives = 36/64 (56%)
Query: 293 RRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSP 352
R D R R + D+ R+ +R RE ER+R R RER +R+R+R+R RERER
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
Query: 353 RRVR 356
R R
Sbjct: 328 ERQR 331
Score = 50.1 bits (118), Expect = 1e-05
Identities = 27/64 (42%), Positives = 37/64 (57%)
Query: 293 RRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSP 352
RR R + R + +R+ +R RER+RER R RER+ +R+R RER RER+R
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 353 RRVR 356
R R
Sbjct: 334 ERDR 337
Score = 48.5 bits (114), Expect = 4e-05
Identities = 23/58 (39%), Positives = 36/58 (62%)
Query: 300 RFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R + R+ ++ R+ +R RERER R+R RER +R+R R+R R+RE+ R R+
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
Score = 47.0 bits (110), Expect = 1e-04
Identities = 51/269 (18%), Positives = 110/269 (40%), Gaps = 52/269 (19%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
++E E + +++ E+ KE + E+D + D KE T D K +
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQT-----DRKRQRRT 291
Query: 643 DLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE 702
+ +E E + + + + ++ + E ++E +++ E E D + +R
Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQ---RETERDREKER------- 341
Query: 703 EEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKE 762
E +RKRQ E++R+R + + G+ + E +E
Sbjct: 342 ERKRKRQTEMDRERNRQ----------------TGREGR-------------RQAERERE 372
Query: 763 HSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDET 822
E + E +RD + E+E + EKD+ +++ K ++ E+D E+
Sbjct: 373 RERERDRQSAREREERERD------RDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
Query: 823 DEPKPKRRKSGDDKDKKEDRDERKKEDKR 851
+ + + R+ +K K +RD ++ D++
Sbjct: 427 ERGRERGRER--EKQKGRERDRERQTDRQ 453
Score = 45.8 bits (107), Expect = 2e-04
Identities = 21/51 (41%), Positives = 31/51 (60%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R R ++ +RK DR RER+R+R + RER R+R R+R R R++ R
Sbjct: 79 RERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERER 129
Score = 45.8 bits (107), Expect = 2e-04
Identities = 22/45 (48%), Positives = 28/45 (62%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
NRK +R RERERER R RE R++ RER +R+ E R R+
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Score = 44.7 bits (104), Expect = 5e-04
Identities = 22/54 (40%), Positives = 32/54 (59%)
Query: 303 GRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
GR+ + D R+ R E+ERER+ RER Q +R+R++ RE+ R RR R
Sbjct: 138 GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Score = 44.7 bits (104), Expect = 5e-04
Identities = 21/44 (47%), Positives = 29/44 (65%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R+ +R RER R+R R RER +R+R RE RE+ER +R R+
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQ 348
Score = 44.3 bits (103), Expect = 7e-04
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 13/70 (18%)
Query: 300 RFSGRNDRGDQVPNRKDDRSRERE-------------RERRRSRERSPQRKRSRERSPRR 346
R S R D+ R+ DR R+R+ R+RR R+R +RKR R+R R
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 347 ERERSPRRVR 356
ERER+ +R R
Sbjct: 310 ERERNRKRER 319
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/58 (41%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 306 DRGDQVPNRKDDRSRER------ERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
DR + R+ DR R+R E ER+R R+R +R+R R R RERER R R+
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
Score = 43.1 bits (100), Expect = 0.002
Identities = 21/57 (36%), Positives = 34/57 (59%)
Query: 300 RFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R R+ + D+ R+ DR +ERER+ R R+R +++R+R++ RE ER R R
Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
Score = 42.7 bits (99), Expect = 0.002
Identities = 19/42 (45%), Positives = 28/42 (66%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
+RK +R RE++R R+R R R QR R +ER + +RER +R
Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117
Score = 42.4 bits (98), Expect = 0.003
Identities = 20/44 (45%), Positives = 27/44 (61%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R+ DR RER RE+ R R+R R+R R+R RER+ R R+
Sbjct: 73 RETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQ 116
Score = 42.4 bits (98), Expect = 0.003
Identities = 23/56 (41%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 304 RNDRGDQVPNRKDDRSRERERE--RRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R+ + ++ NR+ +R RE ERE R R R+ QR+R R+R +ERER R R+
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
Score = 42.4 bits (98), Expect = 0.003
Identities = 19/44 (43%), Positives = 28/44 (63%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
RK +R RE++ ER R+ ER +R + RER R+R+R R+ R
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Score = 42.4 bits (98), Expect = 0.003
Identities = 20/47 (42%), Positives = 30/47 (63%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERER 350
R + ++ R+ +R RERERER R RER + +R RE+ R+R+R
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 287 SQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERER-RRSRERSPQRKRSRERSPR 345
S+ +P + P R G+ + +R+ +R +ERER R +R ER RKR R R
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
Query: 346 RERERSPRRVRR 357
R R+R R R+
Sbjct: 87 RHRKRDRHRERQ 98
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Query: 303 GRNDRGDQVPNRKD-DRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPR 361
G+ +R Q K+ +R +RER+R+ R R +R+R + R RRERER + + R
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
Query: 362 YT 363
++
Sbjct: 205 HS 206
Score = 42.0 bits (97), Expect = 0.003
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R+ DR R+R+R+ R RE+ +R+R+ ER R++ER R R
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDR 268
Score = 41.6 bits (96), Expect = 0.004
Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 10/61 (16%)
Query: 304 RNDRGDQVPNRKDDRSRERERER----------RRSRERSPQRKRSRERSPRRERERSPR 353
+ ++ ++ +R +R RERERER + RER QRK RER + ERER+
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 354 R 354
R
Sbjct: 254 R 254
Score = 41.6 bits (96), Expect = 0.004
Identities = 21/52 (40%), Positives = 27/52 (51%)
Query: 305 NDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
N D+ R +R RERE E R+R R+R R+R RERE+ R R
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
Score = 41.2 bits (95), Expect = 0.006
Identities = 19/52 (36%), Positives = 29/52 (55%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
+R + R++ R ERE +R+R R R R R R+R R+R+R R R+
Sbjct: 57 NRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQ 108
Score = 41.2 bits (95), Expect = 0.006
Identities = 21/67 (31%), Positives = 36/67 (53%)
Query: 290 QPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERE 349
Q AR + R R+ + ++ + DR +RE E++R RE+ + +R RER RE++
Sbjct: 380 QSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQ 439
Query: 350 RSPRRVR 356
+ R R
Sbjct: 440 KGRERDR 446
Score = 40.8 bits (94), Expect = 0.007
Identities = 21/47 (44%), Positives = 31/47 (65%), Gaps = 2/47 (4%)
Query: 313 NRKDDRSR--ERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
+R+ DR R ERERE++ RER+ +R+ R++ RER+R R RR
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Score = 40.8 bits (94), Expect = 0.007
Identities = 20/44 (45%), Positives = 26/44 (59%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R+ +R RER+RE R RE+ +RKR R+ RER R R R
Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364
Score = 40.4 bits (93), Expect = 0.010
Identities = 19/47 (40%), Positives = 30/47 (63%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERER 350
+ +R + R+ +R +R+RERRR ++R +R R RER RE+ER
Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105
Score = 40.4 bits (93), Expect = 0.010
Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
++ R+ +R +ERERER R R+R +R++ RER R+R+R R R
Sbjct: 249 ERASERETERDKERERERDRDRDRD-RRQKERERQTDRKRQRRTERDR 295
Score = 40.4 bits (93), Expect = 0.010
Identities = 16/49 (32%), Positives = 30/49 (61%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
+R Q +++R R+R+R+R++ RER ++ R +R ++RER R
Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Score = 40.0 bits (92), Expect = 0.013
Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 4/54 (7%)
Query: 308 GDQVPNRKDDRSRERERERRRSRERSPQ----RKRSRERSPRRERERSPRRVRR 357
G++ +R+ D RERER+R +ER Q R+R ER+ ++ERER R R
Sbjct: 135 GERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQER 188
Score = 40.0 bits (92), Expect = 0.013
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 6/50 (12%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRE------RSPRRERERSPRRVRR 357
R+ +R RE+ERER+R R+ R+R+R+ R RERER R R+
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380
Score = 39.7 bits (91), Expect = 0.017
Identities = 20/60 (33%), Positives = 34/60 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYT 363
R + D+ R+ +R+R++ERER ++R+ +R+R RE+ + E S R R R T
Sbjct: 159 RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET 218
Score = 39.3 bits (90), Expect = 0.022
Identities = 16/49 (32%), Positives = 30/49 (61%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
D+ R+ ++ R R+R+R R R+R +++R R+ R+R+R R R+
Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQ 124
Score = 39.3 bits (90), Expect = 0.022
Identities = 18/47 (38%), Positives = 29/47 (61%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERER 350
R + D+ +R+ ++ R R++ER R ER +R R R+ +RERER
Sbjct: 105 RERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERER 151
Score = 39.3 bits (90), Expect = 0.022
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 304 RNDRGDQVPNRKDDRSRERERER---RRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R ++ R +R RER+R+R RR +ER Q R R+R R+RE +R R+
Sbjct: 248 RERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Score = 38.9 bits (89), Expect = 0.028
Identities = 18/54 (33%), Positives = 30/54 (55%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R ++ R+ +R R+R+ + +R RER ++ RER RER+R R R+
Sbjct: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ 176
Score = 38.9 bits (89), Expect = 0.028
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPR---RERERSPRRVRR 357
R D+ NR+ R R+ ER R RER R+ +RER R R+R+R R R+
Sbjct: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
Score = 38.1 bits (87), Expect = 0.048
Identities = 19/41 (46%), Positives = 24/41 (58%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R+ DR ER RER R RE+ R+R RER R+ R +R
Sbjct: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 37.7 bits (86), Expect = 0.063
Identities = 18/53 (33%), Positives = 30/53 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R+ + + R+ ++ RE ER R R RER Q+ R R+R + +R+ +R R
Sbjct: 408 RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 37.4 bits (85), Expect = 0.083
Identities = 17/49 (34%), Positives = 29/49 (59%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
D+ +R+ +R R+ E++R RE QR+R ++R R RER R ++
Sbjct: 391 DRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQ 439
Score = 37.0 bits (84), Expect = 0.11
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 303 GRNDRGDQVPNRKDDRSRERERERRRSR--ERSPQRKRSRERSPRRERERSPRRVR 356
GR ++ + +R R+ +RER R R ER +++ RER+ RE ER R R
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER 264
Score = 37.0 bits (84), Expect = 0.11
Identities = 17/51 (33%), Positives = 28/51 (54%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R D+ R+ ++ RERE++R R R R+R +++ R+RER R
Sbjct: 402 RQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDR 452
Score = 37.0 bits (84), Expect = 0.11
Identities = 16/50 (32%), Positives = 29/50 (58%)
Query: 308 GDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
G + ++ +R ++RE ER R R R ++++ RER R+ +R R R+
Sbjct: 410 GQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 36.6 bits (83), Expect = 0.14
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 7/65 (10%)
Query: 299 SRFSGRNDRGDQVPNRKDDRSRER-------ERERRRSRERSPQRKRSRERSPRRERERS 351
+R +GR R R+ +R R+R ERER R R+R +R+R E+ +RE
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415
Query: 352 PRRVR 356
+R R
Sbjct: 416 KQRER 420
Score = 36.6 bits (83), Expect = 0.14
Identities = 16/39 (41%), Positives = 25/39 (64%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERS 351
+R+ +R RER RER + + R R+R +R R+R+RS
Sbjct: 423 DRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRS 461
Score = 35.8 bits (81), Expect = 0.24
Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 12/71 (16%)
Query: 298 PSRFSGRNDRGDQVPNR-------KDDRSRERERERRRSRE-----RSPQRKRSRERSPR 345
P FS R + P R KD +RER R++ RE R +R+ R+R R
Sbjct: 23 PLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR 82
Query: 346 RERERSPRRVR 356
RE++R +R R
Sbjct: 83 REKDRHRKRDR 93
Score = 35.8 bits (81), Expect = 0.24
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R+ + R+RE+ER R R+R + R R R RE R R R
Sbjct: 329 RQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER 371
Score = 35.0 bits (79), Expect = 0.41
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 13/66 (19%)
Query: 304 RNDRGDQVPNRKDDRSRERERE-------------RRRSRERSPQRKRSRERSPRRERER 350
R ++ NR++ R RER+RE R R RER + + R+R RER+R
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 351 SPRRVR 356
+ R
Sbjct: 235 QRKTER 240
Score = 34.7 bits (78), Expect = 0.54
Identities = 17/58 (29%), Positives = 31/58 (53%)
Query: 299 SRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
+R R ++ R DR + +RER R R+ +R+R +R +R+ ER+ ++ R
Sbjct: 122 NRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKER 179
Score = 34.7 bits (78), Expect = 0.54
Identities = 19/58 (32%), Positives = 29/58 (50%)
Query: 300 RFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R + R+ ++ RK +RER R+ RE Q +R RER R+R+ + R R
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER 388
Score = 33.5 bits (75), Expect = 1.2
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 9/96 (9%)
Query: 829 RRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEE 888
RR+ G + + R KD DD E N Q E + + + E DR E
Sbjct: 28 RRRPGSQESPRR----RGLGQAHKDADGDD---RERNRQKERERRREKRQTERETDRKRE 80
Query: 889 EMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRD 924
++D R +R+ +ER +D+EKE+ + RD
Sbjct: 81 RRREKDRHRKRDRH-RER-QRDREKERERQTDRERD 114
Score = 32.7 bits (73), Expect = 2.0
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 7/64 (10%)
Query: 300 RFSGRNDRGDQVPNRKDDRSRERERERR-------RSRERSPQRKRSRERSPRRERERSP 352
R + RN + ++ + RERER+R R ER +R+R RE ER+R
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228
Query: 353 RRVR 356
R R
Sbjct: 229 DRER 232
Score = 32.0 bits (71), Expect = 3.5
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERS-PRRERERSPRRVRR 357
R+ RER ER R++ +R+R R+R RR++ER + R+
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Score = 30.8 bits (68), Expect = 7.7
Identities = 33/137 (24%), Positives = 65/137 (47%), Gaps = 26/137 (18%)
Query: 605 RKEADGEQDEE-EKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLI 663
R++A+ E++ E E+D A+E + + + + D +KE E + +
Sbjct: 364 RRQAERERERERERDRQSARE--------REERERDRDRDRQKERERQTEKDRD------ 409
Query: 664 ARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYIL 723
Q + E+Q+E +K+ E SE+ + +R+ + + E +R+RQ + + R+ +R L
Sbjct: 410 ----GQRETEKQREREKDRE-SERGRERGREREKQKGR-ERDRERQTDRQAGRQRKRSTL 463
Query: 724 PDEPAIIVHPNWAAKSG 740
P P A+SG
Sbjct: 464 YVNP-----PPRTARSG 475
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 75.9 bits (185), Expect = 2e-13
Identities = 128/611 (20%), Positives = 256/611 (41%), Gaps = 76/611 (12%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKD---DGEAKEISTPTHWSKLDPKTM 639
R+ +E L + +K + R++ E DE+ K E + IS S++ + +
Sbjct: 410 RAAFEELEKALST--AQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV 467
Query: 640 KVNDLRKELESRALSSKGLKSQLIARLTKQL--KVEEQKEEQKELEKSEKEEDEDDDRKS 697
V ++K E + + L + +AR ++L K++ ++ E +E K E+ + + K
Sbjct: 468 DV--MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKI 525
Query: 698 EDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRL 757
+KE++E EE+E Q++ IL + + A++ + I+ L L+ L
Sbjct: 526 SQEKEQQESLALEELELQKKA---ILTESENKLRDLQQEAET--YRTRILELESSLEKSL 580
Query: 758 EDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSL-----------------------P 794
++NK S ++++ E ++ V + K L
Sbjct: 581 QENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQT 640
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
E E +EK ++ K+ KDK+ +E K + D K + + + + K
Sbjct: 641 EMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR 700
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
K ++E +Q + E E DE+ + ++++ + +++ E+ KD +
Sbjct: 701 HKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKD-QIN 759
Query: 915 KTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESC 974
+ +++ RD + Q+H LE D++ S ++++ K+ + +S
Sbjct: 760 QLELLLKERD---KHLKEHQAHVEN-LEADIKR---------SEGELQQASAKLDVFQSY 806
Query: 975 FYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDV 1034
T EE + + D+ R+LL + E++ + L + + V
Sbjct: 807 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK---IQV 863
Query: 1035 GSLLQKLEKSEKVRAEVEQKLQLLEE----------KTDEDEKTILNLENSNKSL---SG 1081
L+Q+LEK +E+EQK++ L + K E K IL +E N L G
Sbjct: 864 QDLMQQLEKQ---NSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL-VEKENMILQMREG 919
Query: 1082 ELREVK---KDLSQLQENLKI-SENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNE 1137
+ +E++ + LS ++++ I +E +F+NQ K + + E+ LKK + E
Sbjct: 920 QKKEIEILTQKLSAKEDSIHILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQE 978
Query: 1138 DKDQKSKENGA 1148
K +K EN A
Sbjct: 979 AKLKKELENTA 989
Score = 52.8 bits (125), Expect = 2e-06
Identities = 128/625 (20%), Positives = 256/625 (40%), Gaps = 79/625 (12%)
Query: 579 CLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKT 638
C SE E L ++QL E+LQ K D E+ K + ++ + D K
Sbjct: 309 CTLLTSEKEAL----QEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQD-KG 363
Query: 639 MKVNDLRKE----LESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDD 694
M + + +++ LE + L+S++ T+ ++ EQKE+ + E E+
Sbjct: 364 MVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTA 423
Query: 695 RKSEDDKEEEERKRQEE---IERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSV 751
+K+E+ + + + + E+ IE+ E R L E + + + I L
Sbjct: 424 QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQK 483
Query: 752 LLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKS----LLSLPEKEDKK------- 800
L + L ++ E++ + Q V + KS L EKE ++
Sbjct: 484 LHEKELARKEQ---ELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEEL 540
Query: 801 EKDKKS--KKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDD 858
E KK+ + E K + +++ ET + +S +K +E++++ K D
Sbjct: 541 ELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSK-------DLAVH 593
Query: 859 DETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQM 918
E E++ + E M + + E + +++ + + + + + K +EK + +
Sbjct: 594 LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEK 653
Query: 919 ITINRDLLMAFVYFDQSHCGYLLEKDLEEI------LYTLGLHLSRAQVKKLLNKVVLRE 972
T+ +D + F Q+H + EK LE++ L +L LS +V K +K+ E
Sbjct: 654 ETLLKDKEIIF----QAHIEEMNEKTLEKLDVKQTELESLSSELS--EVLKARHKLE-EE 706
Query: 973 SCFYRKLTDTSKDE--------------------ENHEESESLQEDMLGNRLLLPTPTVK 1012
+ TD K E + HE S E L +++ +K
Sbjct: 707 LSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLK 766
Query: 1013 QESKDVEENVGLIVYNGAMV--DVGSLLQ---KLEKSEKVRAEVEQKLQLLEEKTDEDEK 1067
+ K ++E+ + A + G L Q KL+ + ++ ++ + EE+ + ++
Sbjct: 767 ERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQ 826
Query: 1068 TILNLENSNKSLSGELREV---KKDLSQLQENLKIS-ENMNLQFENQMNKTIRNLSTVMD 1123
+L+LE L+ ++ EV KKD+ + KI +++ Q E Q ++ + + ++
Sbjct: 827 KLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 886
Query: 1124 EIHTVLKKDNVKNEDKDQ--KSKEN 1146
+ L+ N + E Q KEN
Sbjct: 887 VYESKLEDGNKEQEQTKQILVEKEN 911
Score = 48.5 bits (114), Expect = 4e-05
Identities = 118/564 (20%), Positives = 219/564 (38%), Gaps = 70/564 (12%)
Query: 588 TLSRGYKQQLVEKLQGERKEA-----DGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
++S K+ + L+ + E D QD K D +KE + ++D + K +
Sbjct: 1386 SISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALE--QVDDWSNKFS 1443
Query: 643 DLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDD----DRKSE 698
+ +K+ +SR + +L +L + K +K+EQ L K E ++ + E
Sbjct: 1444 EWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1503
Query: 699 DDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLS-VLLDYRL 757
DDK + E+K + + I+ E I + I SL+ VL +Y
Sbjct: 1504 DDKSKMEKKESNLETELKSQTARIMELEDHIT----------QKTIEIESLNEVLKNYNQ 1553
Query: 758 EDNKEHSFEVSLFAELFNEMLQ-RDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKE 816
+ + EH EL ++ ++ G + EK E S K E + KK+
Sbjct: 1554 QKDIEHK-------ELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK 1606
Query: 817 ERDDETDEPKPKRRKSGDDKDKKEDRDERK-KEDKRKDDSKDDDETEEDNNQDEYDPMEA 875
E + K K + +D+ E K E KRK + K ++ +Q E E
Sbjct: 1607 ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQME----EK 1662
Query: 876 EEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQS 935
EE + + E+ + +R+ + E K E +++ + + R Y +Q
Sbjct: 1663 EEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQE 1722
Query: 936 HCGY--LLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRES----------CFYR-KLTDT 982
++K EE + L +L+ + +KLL +V + C Y+ +L
Sbjct: 1723 EADSQGCVQKTYEEKISVLQRNLT--EKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL 1780
Query: 983 SKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVG------- 1035
E E +S M+G+ +++E ++ + LIV + G
Sbjct: 1781 EHAEAKQHEDQS----MIGH--------LQEELEEKNKKYSLIVAQHVEKEGGKNNIQAK 1828
Query: 1036 -SLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQ 1094
+L + +K E E Q+LE+K E + ++ + ++ EL + L LQ
Sbjct: 1829 QNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQ 1888
Query: 1095 ENLKISENMNLQFENQMNKTIRNL 1118
+ ++ L EN K+ +L
Sbjct: 1889 QMDGRNKPTELLEENTEEKSKSHL 1912
Score = 48.5 bits (114), Expect = 4e-05
Identities = 55/250 (22%), Positives = 118/250 (47%), Gaps = 29/250 (11%)
Query: 583 RSEWETLSRGY-KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKV 641
R E E L+ Y K Q ++++ G K E EE ++ + P S ++ +
Sbjct: 1871 RVEMEELTSKYEKLQALQQMDGRNKPT--ELLEENTEEKSKSHLVQPKLLSNMEAQH--- 1925
Query: 642 NDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK 701
NDL +L + L +++ RL K L++ +KE Q+ELE +KE D++ + K + ++
Sbjct: 1926 NDLEFKLAGAEREKQKLGKEIV-RLQKDLRML-RKEHQQELEILKKEYDQEREEKIKQEQ 1983
Query: 702 EEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIM-SLSVLLDYRLEDN 760
E+ E K +++ RE + A K + + +I +++ + E
Sbjct: 1984 EDLELKHNSTLKQLMRE------------FNTQLAQKEQELEMTIKETINKAQEVEAELL 2031
Query: 761 KEHSFEVSLFAELFNEMLQRDFGV----RIYKSLLSLPEKE-DKKEKDKKSKKDERKDKK 815
+ H E + +L ++ ++D + + Y+ +L E+E K +D +++ +E + K
Sbjct: 2032 ESHQEETN---QLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKY 2088
Query: 816 EERDDETDEP 825
+++ ++ + P
Sbjct: 2089 QQKLEQEENP 2098
Score = 40.8 bits (94), Expect = 0.007
Identities = 119/597 (19%), Positives = 242/597 (40%), Gaps = 64/597 (10%)
Query: 592 GYKQQL-VEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDP---KTMKVNDLRKE 647
G KQ + +LQ + K+ + +D+ + K H KL+ K++K N +E
Sbjct: 1101 GVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK-----AHLEKLEVDLNKSLKENTFLQE 1155
Query: 648 --LESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKS-EKEEDEDDDRKSEDDKEEE 704
+E + L+ + + ++ LT +LK + EE + L+ S EK +D+ E K E
Sbjct: 1156 QLVELKMLAEEDKRK--VSELTSKLKTTD--EEFQSLKSSHEKSNKSLEDKSLEFKKLSE 1211
Query: 705 E---------RKRQEEIERQRRERRYILPDEPAIIV-------HPNWAAKSGKF--DCSI 746
E +K + +E + E I + I+ H K C++
Sbjct: 1212 ELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTV 1271
Query: 747 MSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKS 806
L L E+ +++ +S F + +++ +++ ++ K+ + +KE +K
Sbjct: 1272 SELEAQLRQLTEE--QNTLNIS-FQQATHQLEEKENQIKSMKA--DIESLVTEKEALQKE 1326
Query: 807 KKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNN 866
++++ E+ T K KE+ E+K E D + N+
Sbjct: 1327 GGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNS 1386
Query: 867 QDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLL 926
+ A + ++ DEE+ D +D++ + + SK+K Q+ +
Sbjct: 1387 ISLSEKEAAISSLRKQ--YDEEKCELLDQVQDLS-FKVDTLSKEKISALEQVDDWSNKFS 1443
Query: 927 ----MAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQV---KKLLNKVVLRESCFYRKL 979
A F Q H + E ++ L + + Q+ K+ L++ R C ++
Sbjct: 1444 EWKKKAQSRFTQ-HQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM 1502
Query: 980 TDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEE-NVGLIVYNGAM-VDVGSL 1037
D E E + + R++ + Q++ ++E N L YN ++ L
Sbjct: 1503 EDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKEL 1562
Query: 1038 LQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENL 1097
+QKL+ +++ E + +++ EEK IL LEN S+ EL KK+L + ++
Sbjct: 1563 VQKLQHFQELGEEKDNRVKEAEEK-------ILTLENQVYSMKAELETKKKELEHVNLSV 1615
Query: 1098 KISEN----MNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKN-EDKDQKSKENGAS 1149
K E + + E++ + L ++ +KK + E+K+++ K+ S
Sbjct: 1616 KSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTES 1672
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 75.5 bits (184), Expect = 3e-13
Identities = 111/585 (18%), Positives = 253/585 (43%), Gaps = 66/585 (11%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
+ E + L +++ +++ + + +E + Q EEE+ GE +E + K ++
Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 643 D-----LRKELESRALSSKGLKSQLIARLTKQ----LKVEEQKEEQKELEKSEKEEDEDD 693
LR+E E R + + + L ++ L+ E +K ++ELE+ +EE+E
Sbjct: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147
Query: 694 DRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSG-----KFDCSIMS 748
+ + +EE E++R++E+ERQ RE + +E ++ + + + +
Sbjct: 1148 QEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207
Query: 749 LSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIY---KSLLSLPEKEDKKEKDKK 805
YR ED + ++ E E RD ++Y + + ED + +D++
Sbjct: 1208 QKRKQRYRDEDQRS---DLKWQWEPEKENAVRD--NKVYCKGRENEQFRQLEDSQLRDRQ 1262
Query: 806 SKKDERK--DKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEE 863
S++D + +++ERD E + + ++R ++++ +R+E+K+ +R S+++ +
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
Query: 864 DNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINR 923
+ ++ + E + R+EE++ + +++ + R +ER K +E+E ++
Sbjct: 1323 EEREE-----KRRRQETDRKFREEEQLLQEREEQPLRR--QERDRKFREEELR-----HQ 1370
Query: 924 DLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTS 983
+ F+ +Q E+ + L Q+++ ++ E ++L+
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE---QQLSRQE 1427
Query: 984 KDEENHEESESLQEDMLGNRLLLPTPTVKQE--SKDVEENVGLIVYNGAMVDVGSLLQKL 1041
+D + EE + ++ + L ++QE K EE LLQ+
Sbjct: 1428 RDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE--------------QLLQER 1473
Query: 1042 EKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISE 1101
E+ + R E ++K E+E+ + E K ELR + + L+E ++
Sbjct: 1474 EEQQLHRQERDRKFL-------EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 1102 NMN----LQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQK 1142
LQ E Q+ + R D +++ ++ E ++Q+
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Score = 70.9 bits (172), Expect = 7e-12
Identities = 87/475 (18%), Positives = 210/475 (44%), Gaps = 32/475 (6%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKL--DPKTMKVNDLRKELESR 651
+QQL K + ER+E Q EE ++ E +E +L + + + LR+E E
Sbjct: 303 EQQLRRKQEEERRE----QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 652 ALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEE 711
+ + Q R +QL+ E+Q +++L + ++ E R+ + + E++ +R+++
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 712 IERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDY--RLEDNKEHSFEVSL 769
+ R+++ RR E H + + D+ R E+ + H
Sbjct: 419 LRREQQLRR-----EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE----- 468
Query: 770 FAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSK--KDERKDKKEER-DDETDEPK 826
E + L+RD + L L E+E +++++++ + + E+++++E+R + +E +
Sbjct: 469 -QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 827 PKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRD 886
++R + + ++E + R++ KR+++ + + E E + E + + + EE+ R
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR- 586
Query: 887 EEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLE 946
++ KR+ + + + K + E+E+ + + R+ ++ LL+ + +
Sbjct: 587 -QQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE------EPEEERRQQLLKSEEQ 639
Query: 947 EILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLL 1006
E L + + ++ K E ++L ++E +E +++ R+
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Query: 1007 PTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEK 1061
P + + + + VY+ G ++ ++ E+ R E +LQ EE+
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQ--RRRQEQEEKRRRRESELQWQEEE 752
Score = 70.5 bits (171), Expect = 9e-12
Identities = 108/573 (18%), Positives = 239/573 (41%), Gaps = 88/573 (15%)
Query: 580 LPTRSEWETLSRGYK-QQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKT 638
L + E E L + + +Q + + Q ER+E +++EE++ + E +E K + +
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL-----KREQEE 573
Query: 639 MKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSE 698
+ L++E E R K + + + + K+ +VE ++E++ ++ ++EE E++ R+
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 699 DDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLE 758
EE+E +RQ+++ R+++ERR + RL+
Sbjct: 634 LKSEEQEERRQQQLRREQQERR---------------------------------EQRLK 660
Query: 759 DNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEER 818
+E E + L+R+ + L+ E+E +E+ K + + E
Sbjct: 661 REEEE--------ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 819 DDETDEPKPKRRKSGDDKDKKEDRDERKKEDK----RKDDSKDDDETEEDNNQDEYDPME 874
D + + RK + ++E ++R++ + ++++ + EE+ +D +
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ 772
Query: 875 AEEAEDEEDDRDEEEMTKRDDK----RDINRYCKERPSKDKEKEKTQMITINRDLLMAFV 930
AEE + R R+ + R R +E+ +E+EK Q R+
Sbjct: 773 AEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ 832
Query: 931 YFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKV-VLRESCFYRKLTDTSKDEENH 989
+ ++ E+ L+ R + ++L + L+E R+ + +D++
Sbjct: 833 FLEE-------EEQLQR----------RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Query: 990 EESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRA 1049
+ L+E+ R L QE E+ + + + LQ+ E+ ++ R
Sbjct: 876 WQ---LEEERKRRRHTLYAKPALQEQLRKEQQL--------LQEEEEELQREEREKRRRQ 924
Query: 1050 EVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKD--LSQLQENLKISENMNLQF 1107
E E++ + EE+ ++E+ +L E + R+ +KD L Q +E L + E +
Sbjct: 925 EQERQYR-EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL-LGEEPEKRR 982
Query: 1108 ENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKD 1140
+ K R + E +L+++ K ++
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Score = 70.5 bits (171), Expect = 9e-12
Identities = 112/578 (19%), Positives = 243/578 (42%), Gaps = 122/578 (21%)
Query: 585 EWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDL 644
+W+ R ++QQ E+ +R++ + EEK + + +S + + ++ +
Sbjct: 747 QWQEEERAHRQQQEEE---QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE- 802
Query: 645 RKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEK----EEDEDDDRKSEDD 700
R++ E R L + K Q + ++ K + EE+++L++ E+ +E+ED ++ ++
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER 862
Query: 701 KEEEERKRQE----EIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYR 756
+ +E++R + ++E +R+ RR+ L +PA+
Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL--------------------------- 895
Query: 757 LEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKE-DKKEKDKKSKKDERKDKK 815
E L+++ + LL E+E ++E++K+ ++++ + +
Sbjct: 896 ------------------QEQLRKE------QQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 816 EERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDD--DETEEDNNQDEYDPM 873
EE + +E + R E+R++R+++++ + KD + EE +E +
Sbjct: 932 EEEQLQQEEEQLLR----------EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR 981
Query: 874 EAEEAE----DEEDDRDEEEMTKRDDKRDINRYCKERPSKDK---EKEKTQMITINRDLL 926
+E E +EE+ + EEE R+++ R ER + K ++E+ Q++ R+
Sbjct: 982 RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR 1041
Query: 927 MAFVYFDQSHCGYLLEKDL-EEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKD 985
+ Y E++L +E LG + ++L + YRK ++
Sbjct: 1042 R----LQERERQYREEEELQQEEEQLLGEERETRRRQELERQ--------YRK-----EE 1084
Query: 986 EENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSE 1045
E EE + L+E+ R ++E + +E L+ + E+ +
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL--------------REEREK 1130
Query: 1046 KVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNL 1105
+ R E+E++ + EE E+E+ L E K EL ++ +LQ+ E L
Sbjct: 1131 RRRQELERQYREEEEVQQEEEQ--LLREEPEKRRRQELERQYREEEELQQ-----EEEQL 1183
Query: 1106 QFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKS 1143
E Q + +E +K + D+DQ+S
Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Score = 68.6 bits (166), Expect = 3e-11
Identities = 103/563 (18%), Positives = 239/563 (42%), Gaps = 68/563 (12%)
Query: 599 EKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGL 658
++ + ER+ A+GE+ E+++ E ++ + D + + +E E R + L
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQ------RRDEELWRQRQEWQEREERRAEEEQL 193
Query: 659 KSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRE 718
+S T++ EEQ ++ LE K +E K + +E ++R QEE E++ R+
Sbjct: 194 QS-CKGHETEEFPDEEQLRRRELLELRRKGREE----KQQQRRERQDRVFQEEEEKEWRK 248
Query: 719 RRYILPDEPAIIVH--PNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNE 776
R +L E + P + + + + L R E +E E E +
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE-----RQELRRERQEE-----EQQQQ 298
Query: 777 MLQRDFGVRIYKSLLSLPEKEDKKEK-DKKSKKDERKDKKEERDDETDEPKPKRRKSGDD 835
L+R+ +R + ++E+++E+ +++ +++ER++++ R+ E + RR+ ++
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 836 KDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDD 895
+ +++ R E+++E + + ++ E + E ++ E+ R E+++ +
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 896 KR---DINRYCKERPSKDKEKEKTQMITINRDLLMAFVYF---------DQSHCGYLLEK 943
R + R +E + K +++ + + R+ + +Q L++
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
Query: 944 DLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDE-ENHEESESLQEDMLGN 1002
D EE L L + ++ + RE R+ + + + EE E LQ+ +
Sbjct: 479 DQEEERRERWLKLEEEERREQQER---REQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 1003 RLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKT 1062
+ L ++E ++ E Q L++ E+ R E E++ Q L+ +
Sbjct: 536 QQL------RREQEERRE------------------QLLKREEEKRLEQERREQRLKREQ 571
Query: 1063 DEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVM 1122
+E +L E + + R ++ +L++ LK E L+ E + + ++
Sbjct: 572 EERRDQLLKREEERR----QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627
Query: 1123 DEIHTVLKKDNVKNEDKDQKSKE 1145
+ +LK + + + Q +E
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRRE 650
Score = 68.6 bits (166), Expect = 3e-11
Identities = 115/591 (19%), Positives = 259/591 (43%), Gaps = 78/591 (13%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRAL 653
+QQ + + Q ER+E +++EEE+ + + + + + R+ ++SR
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
Query: 654 SSKG-LKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERK-RQEE 711
+ L+S+ AR Q KV + +Q+ + +++E++ R+SE +EEER RQ++
Sbjct: 703 KWQWQLESEADAR---QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ 759
Query: 712 IERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFA 771
E QRR+ + W A+ K + LS R + ++ L A
Sbjct: 760 EEEQRRDFTW------------QWQAEE-KSERGRQRLSARPPLREQRERQ------LRA 800
Query: 772 ELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRK 831
E + QR LPE+E+K+++ ++ +++ K+ + ++E + + + ++
Sbjct: 801 EERQQREQR-----------FLPEEEEKEQR-RRQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 832 SGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEY-----DPMEAEEAEDEEDDRD 886
+++D ++ ER++ +++ D K + EE+ + + ++ + ++++ ++
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 887 EEEMTKRDDKRDINRYCKERPSKDKE---KEKTQMITINRDLLMAFVYFDQSHCGYLLEK 943
EEE +R+++ R +ER +++E +E+ Q++ R+ Q L++
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 944 DLEEILYTLGLHLSRAQVKKLL---------NKVVLRESCFYRKLTD-----TSKDEENH 989
E++L R + +K + +LRE R+ + KDE
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
Query: 990 EESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRA 1049
EE + L+E+ RL ++E + +E L+ L ++ K E+++
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088
Query: 1050 EVEQKLQ---------------LLEEKTDEDEKTILNLENSNK---SLSGELREVKKDLS 1091
E EQ L+ EE+ ++E+ +L E + L + RE ++++
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE-EEEVQ 1147
Query: 1092 QLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQK 1142
Q +E L + E + ++ + R + E +L+++ K + ++
Sbjct: 1148 QEEEQL-LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Score = 65.5 bits (158), Expect = 3e-10
Identities = 93/542 (17%), Positives = 231/542 (42%), Gaps = 53/542 (9%)
Query: 585 EWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDL 644
E E L + +Q L E+ + R+E + + EEE+ + ++ + D K +
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEK 1231
Query: 645 RKELESRALSSKGLKSQLIARLT-KQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK-- 701
+ + KG +++ +L QL+ + +++ + L ++E D + +R+ +
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291
Query: 702 ---EEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLE 758
EEE+ +R+E+ E +RR+R+ ++ + + + D LL R E
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKS-QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
Query: 759 DNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEER 818
F E E+ ++ G + L ++ ++E+++K K+E++ + +ER
Sbjct: 1351 QPLRRQERDRKFRE--EELRHQEQG----RKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 819 DDETDEPKPKR---------RKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDE 869
+ + + + ++ R+ D K ++E++ R++E +RK ++ +E + +
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 870 YDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAF 929
+ +E E+++ R E + ++++ + R +ER K +E+E + L
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRR--QERDRKFREQELRSQEPERKFLEEEQ 1522
Query: 930 VYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENH 989
Q L+++ + G + + +K + LR+ ++L+ +D +
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 990 EESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRA 1049
E + ++ +QE K +E+ L++ E +++R
Sbjct: 1583 LEEQKVRRQ-------------EQERKFMEDE--------------QQLRRQEGQQQLRQ 1615
Query: 1050 EVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFEN 1109
E ++K + E+ E E+ L+ + ++ E ++++ + ++ L+ + + E
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR--QEREQQLRHDRDRKFREEE 1673
Query: 1110 QM 1111
Q+
Sbjct: 1674 QL 1675
Score = 65.5 bits (158), Expect = 3e-10
Identities = 69/340 (20%), Positives = 158/340 (46%), Gaps = 26/340 (7%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVND-LRKELESRA 652
+++ +E+ Q R+E + EEE+ E +E H + D K ++ LR++ R
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREE--QQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 653 LSSKGLKSQLIAR--------LTKQLKVEEQKEEQKELEKSEKEED--EDDDRKSEDDKE 702
+ L+SQ R L +Q + + +E+++L + E+ + +D DRK ++++
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
Query: 703 EEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKE 762
+ + ++++ RQ R+R++ L ++ + K + + + R E +++
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQK--VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 763 HSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDET 822
+ L E + L R R K L P+ ++ + + +RK ++EE+ +
Sbjct: 1621 FREDEQLLQEREEQQLHRQ--ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 823 DEPKPKRRKSGDDKDKKEDRDERKKEDKRK----DDSKDDDETEEDNNQDEYDPMEAEEA 878
E + RR+ D K ++E++ R++E +RK + E E ++E E E+
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 879 EDEEDDR-----DEEEMTKRDDKRDINRYCKERPSKDKEK 913
+ +R +EE++ +++ + R ++R +++E+
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 62.0 bits (149), Expect = 3e-09
Identities = 88/505 (17%), Positives = 220/505 (43%), Gaps = 79/505 (15%)
Query: 670 LKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEER---------KRQEEIERQRRERR 720
L+ Q+E+Q+ E +++ +E+ ++ ++E+ER ++QE +E++ R+RR
Sbjct: 110 LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRR 169
Query: 721 YILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQR 780
DE W + + + +L+ K H E F + E L+R
Sbjct: 170 ----DEELWRQRQEWQEREER---------RAEEEQLQSCKGH--ETEEFPD--EEQLRR 212
Query: 781 DFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKD--------KKEERDDETDEPKPKRRKS 832
+ + + +++ ++ +D+ +++E K+ +KEE + +EP+ +R
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Query: 833 GDDK-----DKKEDRDERKKEDKRKDDSKDDDE----TEEDNNQDEYDPMEAEEAEDEED 883
+++ +++E R ER++E++++ + + + EE+ + + + E +E ++++
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 884 DRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEK 943
+R E+++ + ++R +E+ + +++E+ + + R+ E+
Sbjct: 333 ERREQQLRREQEER------REQQLRREQEEERREQQLRRE----------------QEE 370
Query: 944 DLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNR 1003
+ E L R Q +L + LR R+ ++++ E + +E L
Sbjct: 371 ERREQQLRREQQLRREQ--QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 1004 LLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTD 1063
K E + E+ + + L++ E++E+ E +K QL ++ +
Sbjct: 429 QEEERHEQKHEQERREQRL-----KREQEERRDWLKREEETERHEQE-RRKQQLKRDQEE 482
Query: 1064 EDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMD 1123
E + L LE + E RE + L + QE + + E ++ + +R+ +
Sbjct: 483 ERRERWLKLEEEERREQQERRE--QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 1124 E----IHTVLKKDNVKNEDKDQKSK 1144
E +LK++ K +++++ +
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQ 565
Score = 60.8 bits (146), Expect = 7e-09
Identities = 97/535 (18%), Positives = 238/535 (44%), Gaps = 61/535 (11%)
Query: 632 SKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE 691
++ D K + D R+E + R + + + ++ K +EQ+ E E E+ ++++
Sbjct: 101 ARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQER 160
Query: 692 DDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKF-DCSIMSLS 750
+ R + EE R+RQE ER+ ERR + H ++ +F D +
Sbjct: 161 LEQRDRQRRDEELWRQRQEWQERE--ERRAEEEQLQSCKGH-----ETEEFPDEEQLRRR 213
Query: 751 VLLDYRLEDNKEHSFEVSLFAE-LFNEMLQRDFGVR---IYKSLLSLPEKEDKK-----E 801
LL+ R + +E + + +F E ++++ R + K L E+E ++ E
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 802 KDKKSKKDERKDKKEERDDETDEPKPKRR----KSGDDKDKKEDRDERKKEDKRKDDSKD 857
++++ +K ER++ + ER +E + + RR + +++++E ++ER+++ +R++ +
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE--QQ 331
Query: 858 DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQ 917
++ E+ +++ + E + ++E++R E+++ + ++ + + +E++ +
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 918 MITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYR 977
+ R+ L ++ + L R Q +L + LR R
Sbjct: 392 EQQLRRE--------------QQLRREQQ---------LRREQ--QLRREQQLRREQQLR 426
Query: 978 KLTDTSKDEENHEE---SESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDV 1034
+ + + E+ HE+ + L+ + R L ++ + +E + +
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKRE--EETERHEQERRKQQLKRDQEEER 484
Query: 1035 GSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELR---EVKKDLS 1091
KLE+ E+ R + E++ Q L + +E + L + + L LR +++++
Sbjct: 485 RERWLKLEEEER-REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 1092 QLQEN-LKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
+ +E LK E L+ E + + R D++ LK++ + + + ++ +E
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQL---LKREEERRQQRLKREQE 595
Score = 58.5 bits (140), Expect = 3e-08
Identities = 70/349 (20%), Positives = 155/349 (44%), Gaps = 26/349 (7%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEAD-GEQDEEEKDDGEAKEISTPTHWSKL--DPKTM 639
R + R K + E+L+ ER+E Q+ + K E +++ K D + +
Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604
Query: 640 KVNDLRKEL-ESRALSSKGLKSQLIARLTKQLKVEEQK----EEQKELEKSEKEED--ED 692
+ + +++L + R + + L R +QL +E+ EE+ +L + E+E+ D
Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD 1664
Query: 693 DDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVL 752
DRK ++++ + ++++ RQ R+R++ ++ + KF L
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL-----RRQERERKFLQEEQQLR-- 1717
Query: 753 LDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPE-KEDKKEKDKKSKKDER 811
R E ++ E L E E L+R Y+ +L + + +++E+ + ++ +R
Sbjct: 1718 ---RQELERKFREEEQLRQETEQEQLRRQ---ERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 812 KDKKEERDDETDEPKPKRRKSGDDKDKKED--RDERKKEDKRKDDSKDDDETEEDNNQDE 869
K ++EE+ + E + R + D K ++E+ R ER+++ R EE+ Q E
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 870 YDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQM 918
+ D + +E+ T+ +R+ +E K +++ + ++
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
Score = 51.2 bits (121), Expect = 6e-06
Identities = 50/257 (19%), Positives = 116/257 (45%), Gaps = 27/257 (10%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
R E + L G +QQL + + + + +Q ++ + + + +L+ K +
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 643 DLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK- 701
LR+E E L + +++ +QL+ E ++++ + E+ K +E+ R+ +++
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEE--EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 702 ---EEEERK-RQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSV-LLDYR 756
+E +RK R+EE RQ RE + + P + + GK+ L + + R
Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQ-----------RDGKYRWEEEQLQLEEQEQR 1836
Query: 757 LEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKD--ERKDK 814
L ++ + + ++ R + L E++ ++E+++K +++ R+ K
Sbjct: 1837 LRQERDRQYRAE------EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Query: 815 KEERDDETDEPKPKRRK 831
+E+R + E K + K
Sbjct: 1891 EEQRHRQVGEIKSQEGK 1907
Score = 42.0 bits (97), Expect = 0.003
Identities = 62/357 (17%), Positives = 136/357 (38%), Gaps = 47/357 (13%)
Query: 774 FNEMLQRDFGVR--IYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRK 831
FNE L F V Y +L +++K K+ +D+++E D EP+ ++ +
Sbjct: 71 FNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLE 130
Query: 832 SGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDP---MEAEEAEDEEDDRDEE 888
+ +++ R E+++E ++ + E E ++ D + +E ++ E+ R EE
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEE 190
Query: 889 EMTKRDDKRDINRYCKERPSKDKE---------KEKTQMITINRDLLMAFVYFDQSHCGY 939
E + + + E + +E +EK Q +D +
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF------------ 238
Query: 940 LLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDM 999
++ EE + + R + +KL + R+ + K E E +E+
Sbjct: 239 ---QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Query: 1000 LGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLE 1059
RL +++ ++ E ++ E+ E+ + E++ Q L
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQE---------------ERREQQERREQQEERREQQLR 340
Query: 1060 EKTDEDEKTILNLENSNKSLSGELR---EVKKDLSQLQENLKISENMNLQFENQMNK 1113
+ +E + L E + +LR E ++ QL+ ++ L+ E Q+ +
Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397
Score = 40.4 bits (93), Expect = 0.010
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 4/102 (3%)
Query: 260 LLQTQPQPLLQQPQQKAGLLQPP---VRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKD 316
+L+ + + L ++ Q+ LQ +R + + + R + R R Q+ +++
Sbjct: 252 VLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE 311
Query: 317 DRSRERERERRRSRERSPQRKRSRERSPRRER-ERSPRRVRR 357
+ RE++ ERR +ER Q++ RE+ RRE+ ER +++RR
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Score = 37.7 bits (86), Expect = 0.063
Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 1/113 (0%)
Query: 241 QPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSR 300
+ +PQ + Q + L + + + Q+ +Q+ L+ ++ + + RR R
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 301 FSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPR 353
+ +R +Q R++ + R + ERR + R Q + RE+ RRE+E R
Sbjct: 322 RE-QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Score = 34.7 bits (78), Expect = 0.54
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 262 QTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRE 321
+ Q Q L++ QQ L+ + Q R + R + +R +Q R+ + RE
Sbjct: 293 EEQQQQRLRREQQ----LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 322 RERERRRSRERSPQRKRSRERSPRRERE-RSPRRVRR 357
++ R + ER Q+ R + RRE++ R +++RR
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Score = 33.5 bits (75), Expect = 1.2
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 288 QPQPARRLDPPSRFSGRNDRGDQVPNR---KDDRSRERERERRRSRERSPQRKRSRERSP 344
+ QP RR + +F R + + ++ R R +ERER+ +E R + RE+
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 345 RRERERSPRRVRRVVPR 361
R++R+R R + + R
Sbjct: 1409 RQDRDRKFREEEQQLSR 1425
Score = 32.0 bits (71), Expect = 3.5
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R R + + D+ +RE ERR+ R + Q +R +R R E ER + RR
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Score = 32.0 bits (71), Expect = 3.5
Identities = 13/43 (30%), Positives = 26/43 (60%)
Query: 312 PNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
P +++ + R +E+E +R R S + + ER+ R+++E RR
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
Score = 31.2 bits (69), Expect = 5.9
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 14/134 (10%)
Query: 264 QPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRK-------- 315
+ Q L ++ +Q+ + + + + Q RR + +F + R Q P RK
Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS-QEPERKFLEEEQQL 1524
Query: 316 --DDRSRE--RERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSL 371
R R+ +E ++ R +ER QR++ R+R R E + R + + R + KF L
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE-RDRKFRL 1583
Query: 372 DCPSCDMMELRRRY 385
+ E R++
Sbjct: 1584 EEQKVRRQEQERKF 1597
Score = 30.8 bits (68), Expect = 7.7
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 10/62 (16%)
Query: 307 RGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRE----------RERSPRRVR 356
R +Q R+ RE+E ERR + R Q + RE+ RRE RE+ RR +
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
Query: 357 RV 358
++
Sbjct: 400 QL 401
Score = 30.8 bits (68), Expect = 7.7
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 314 RKDDRSRERERERRRSRERSPQR-KRSRERSPRRERERSPRRVRR 357
R++ + R ++ RR ER QR KR E ++R RS +++RR
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Score = 30.8 bits (68), Expect = 7.7
Identities = 18/63 (28%), Positives = 37/63 (58%), Gaps = 9/63 (14%)
Query: 304 RNDRGDQVPNRKDDRSRERER-ERRRSRERSPQR--------KRSRERSPRRERERSPRR 354
+ +R +Q+ R++++ E+ER E+R RE+ +R +R ++R R + ER +R
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 355 VRR 357
++R
Sbjct: 602 LKR 604
Score = 30.8 bits (68), Expect = 7.7
Identities = 20/92 (21%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 273 QQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDR----GDQVPNRKDDRSRERERERRR 328
+QK + + + Q RR + + DR +Q+ ++++ R+ R+
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 329 SRERSPQ-RKRSRERSPRRERERSPRRVRRVV 359
E PQ R++ RE+ R +R+R R +++
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 74.7 bits (182), Expect = 5e-13
Identities = 121/565 (21%), Positives = 234/565 (41%), Gaps = 109/565 (19%)
Query: 674 EQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILP--------- 724
E KE+ E E+EE+EDD+++ ED+ EEE EEIE ER L
Sbjct: 268 ELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEE----EEIEPFPEERENFLQQLYKFMEDR 323
Query: 725 ----DEPAIIVHPN--------WAAKSGKFDCSIMSLSV-----------LLDYRLEDNK 761
++ ++ + N K G FD +I S +V +L+ N
Sbjct: 324 GTPINKRPVLGYRNLNLFKLFRLVHKLGGFD-NIESGAVWKQVYQDLGIPVLNSAAGYNV 382
Query: 762 EHSFEVSLFA-ELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDD 820
+ +++ L+ E + +F + + + +++ KE + K+ K K++ + KE + +
Sbjct: 383 KCAYKKYLYGFEEYCRSANIEFQMALPEKVVNKQCKECENVKEIKVKEENETEIKEIKME 442
Query: 821 ETDEPKPKRRKSGDDK-------------------------DKKEDRDERKKEDKRKDDS 855
E P+ K +D+ D++++ + +K ED D
Sbjct: 443 EERNIIPREEKPIEDEIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDD 502
Query: 856 KDDDET--------------------EEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDD 895
KDDD T +E N +++ D EAEE E+EE++ ++E+ ++
Sbjct: 503 KDDDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEEEEEEDEDDDDNNE 562
Query: 896 KRDINRY-----CKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILY 950
+ + Y + R + K ++ + + D+ V + +CG+ + D E I
Sbjct: 563 EEEFECYPPGMKVQVRYGRGKNQKMYEASIKDSDVEGGEVLYLVHYCGWNVRYD-EWIKA 621
Query: 951 TLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPT 1010
+ + V K+ ++ ++ D KD++ ++ + L P+
Sbjct: 622 DKIVRPADKNVPKIKHRKKIKNK------LDKEKDKDEKYSPKNCKLRRLSKPPFQTNPS 675
Query: 1011 VKQESK-DVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTD---EDE 1066
+ SK D+ + + +++ S+L L+ SE + EQ+ + + D ++E
Sbjct: 676 PEMVSKLDLTDAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDERGAQDMDNNGKEE 735
Query: 1067 KTILNLENSNKSLSGELREVKKDLSQLQEN-----LKISENMNLQFENQMNKTIRNLS-- 1119
I +L N+ L +E + S L+EN L IS+ ++ E ++ K I LS
Sbjct: 736 SKIDHLTNNRNDLIS--KEEQNSSSLLEENKVHADLVISKPVSKSPE-RLRKDIEVLSED 792
Query: 1120 TVMDEIHTVLKKDNVKNEDKDQKSK 1144
T +E K+ +VK + D+ SK
Sbjct: 793 TDYEEDEVTKKRKDVKKDTTDKSSK 817
Score = 63.5 bits (153), Expect = 1e-09
Identities = 105/518 (20%), Positives = 199/518 (38%), Gaps = 72/518 (13%)
Query: 605 RKEADGEQDEEEKDD-----GEAKEI--STPTHWSKLDPKTMKVNDLRKELESRALSSKG 657
R+E E + E K++ G K + S PTH + +K + + L+ + +
Sbjct: 450 REEKPIEDEIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 509
Query: 658 LKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRR 717
+ L +KVE ++E+ K +++ KEEDEDD+ E+++EEEE + +++ +
Sbjct: 510 VDESL------NIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEEEEEEDEDDDDNNEE 563
Query: 718 ERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEM 777
E P + V ++ SI +D+ EV
Sbjct: 564 EEFECYPPGMKVQVRYGRGKNQKMYEASI-----------KDSDVEGGEVLYLVHYCGWN 612
Query: 778 LQRDFGVRIYKSLLSLPEKEDKK-EKDKKSKKDERKDKKEERDDETDEPK--PKRRKSGD 834
++ D ++ K + DK K K KK + K KE+ DE PK RR S
Sbjct: 613 VRYDEWIKADK----IVRPADKNVPKIKHRKKIKNKLDKEKDKDEKYSPKNCKLRRLSKP 668
Query: 835 DKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRD 894
+ K D + D + + ++A E+ E+ ++++E
Sbjct: 669 PFQTNPSPEMVSKLDLTDAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDE------ 722
Query: 895 DKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGL 954
R ++ + KE+ K +T NR+ L++ ++ + LLE++ +
Sbjct: 723 ------RGAQDMDNNGKEESKIDHLTNNRNDLIS---KEEQNSSSLLEENKVHADLVISK 773
Query: 955 HLSRAQVKKLLNKVVLRESCFY------RKLTDTSKDEENHEESESLQED---MLGNRLL 1005
+S++ + + VL E Y +K D KD + ++
Sbjct: 774 PVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKRRYCNTEEC 833
Query: 1006 LPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEK---- 1061
L T + ++ + + L + N + S + E+ K + +K LEEK
Sbjct: 834 LKTGSPGKKEEKAKNKESLCMENSS----NSSSDEDEEETKAKMTPTKKYNGLEEKRKSL 889
Query: 1062 ---------TDEDEKTILNLENSNKSLSGELREVKKDL 1090
++ EK I L NS++ L + +KD+
Sbjct: 890 RTTGFYSGFSEVAEKRIKLLNNSDERLQNSRAKDRKDV 927
Score = 40.0 bits (92), Expect = 0.013
Identities = 78/386 (20%), Positives = 147/386 (38%), Gaps = 94/386 (24%)
Query: 802 KDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDET 861
KD K RKD E D PKP + E R K + K+D +
Sbjct: 218 KDGKFTSVPRKDVHEITSDTA--PKPDAVLKQAFEQALEFHKSRTIPANWKTELKEDSSS 275
Query: 862 EEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK---TQM 918
E AEE E+EEDD E+E +++ +I + +ER + ++ K +
Sbjct: 276 SE-----------AEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRG 324
Query: 919 ITINRDLLMAF-----------------------------VYFD------QSHCGYLLEK 943
IN+ ++ + VY D S GY ++
Sbjct: 325 TPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKC 384
Query: 944 DLEEILYTLGLHLSRAQVK---KLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDML 1000
++ LY + A ++ L KVV ++ + + EEN E + ++ M
Sbjct: 385 AYKKYLYGFEEYCRSANIEFQMALPEKVVNKQCKECENVKEIKVKEENETEIKEIK--ME 442
Query: 1001 GNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEE 1060
R ++P +E K +E+ ++E+ E ++ + K LLE
Sbjct: 443 EERNIIP-----REEKPIED-------------------EIERKENIKPSLGSKKNLLES 478
Query: 1061 -KTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLS 1119
T D++ +N++ K E + K D + ++ E++N++ E + K
Sbjct: 479 IPTHSDQEKEVNIK---KPEDNENLDDKDD-----DTTRVDESLNIKVEAEEEKAKSG-- 528
Query: 1120 TVMDEIHTVLKKDNVKNEDKDQKSKE 1145
DE + +D+ + E+++++ +E
Sbjct: 529 ---DETNKEEDEDDEEAEEEEEEEEE 551
Score = 32.7 bits (73), Expect = 2.0
Identities = 62/345 (17%), Positives = 132/345 (38%), Gaps = 49/345 (14%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRAL 653
K++ + + E +E + E++E+E DD +E + P MKV +++ +
Sbjct: 533 KEEDEDDEEAEEEEEEEEEEEDEDDDDNNEEEEFECY-----PPGMKVQVRYGRGKNQKM 587
Query: 654 SSKGLKSQ---------LIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEE 704
+K L+ ++ +E + K + ++K + RK +K ++
Sbjct: 588 YEASIKDSDVEGGEVLYLVHYCGWNVRYDEWIKADKIVRPADKNVPKIKHRKKIKNKLDK 647
Query: 705 ERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKE-H 763
E+ + E+ + + R + +P +P+ ++S L D + D
Sbjct: 648 EKDKDEKYSPKNCKLRRL--SKPPFQTNPS---------PEMVSKLDLTDAKNSDTAHIK 696
Query: 764 SFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKK---EKDKKSKKDERKDK-KEERD 819
S E++ G++ +S E+ED++ + D K++ + D R+
Sbjct: 697 SIEITSILN----------GLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRN 746
Query: 820 DETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAE 879
D + + ++ D K K + + D E ++ E D + + +
Sbjct: 747 DLISKEEQNSSSLLEENKVHADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKD 806
Query: 880 DEEDDRDEEEMTKRDDKRDINRYCKER-------PSKDKEKEKTQ 917
++D D+ +K KR RYC P K +EK K +
Sbjct: 807 VKKDTTDKS--SKPQIKRGKRRYCNTEECLKTGSPGKKEEKAKNK 849
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 73.9 bits (180), Expect = 8e-13
Identities = 56/235 (23%), Positives = 109/235 (46%), Gaps = 39/235 (16%)
Query: 673 EEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEE------RKRQEEIERQRRERRYILPDE 726
+ Q+E + EK+EKE D D R E ++E+E R++Q EIER R +
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK------ 129
Query: 727 PAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEM-LQRDFGVR 785
+ G+ D E +E E + E +RD
Sbjct: 130 -----------QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD---- 174
Query: 786 IYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDER 845
E+E +KE++ + +D ++D ++ER+ +TD + ++RK+ ++ ++ DR+
Sbjct: 175 --------REREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE 226
Query: 846 KKEDKRKDDSKDDDE-TEEDNNQDEYDPMEAEEAEDEEDDRDE--EEMTKRDDKR 897
++ D+R++ +D D E D +D + + E ++ + +R E +E +R+DK+
Sbjct: 227 RETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Score = 62.8 bits (151), Expect = 2e-09
Identities = 31/120 (25%), Positives = 64/120 (53%), Gaps = 3/120 (2%)
Query: 799 KKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRD---ERKKEDKRKDDS 855
+KEK+ +D K + ERD E ++ K + R+ ++++ DRD ER+++ ++ D
Sbjct: 104 RKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDG 163
Query: 856 KDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
+ + ETE + +++ E E D + RD E+ +R R+ +R K + + +E ++
Sbjct: 164 QRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
Score = 60.8 bits (146), Expect = 7e-09
Identities = 57/258 (22%), Positives = 104/258 (40%), Gaps = 53/258 (20%)
Query: 606 KEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIAR 665
K+ADG+ + E+D ++ KT K D ++ + R
Sbjct: 70 KDADGDDRQRERD--------------RVREKTEKERDRDRKRDRER-----------RR 104
Query: 666 LTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPD 725
K+ +E+Q E+E+ + E + + D E ER R E ER+R+ +
Sbjct: 105 KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEK----- 159
Query: 726 EPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEM-------L 778
+ G+ + D E KE E + E
Sbjct: 160 -----------DRDGQRETETERER---DREREKQKERETERDRDRQRDTEKERERQTDR 205
Query: 779 QRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDK 838
+RD + ++E ++E D++ ++ +D+ +ERD E D + + RK K++
Sbjct: 206 ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERD--RKEERKKERKKER 263
Query: 839 KEDRDERKKEDKRKDDSK 856
K++R E+KKE+KR++D K
Sbjct: 264 KKERKEKKKEEKRREDKK 281
Score = 60.8 bits (146), Expect = 7e-09
Identities = 31/127 (24%), Positives = 67/127 (52%), Gaps = 7/127 (5%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
E E +E++K+ ++ +D+ ER+ + D K + R++ D+D + + + ++ D+ ++
Sbjct: 120 EIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREK 179
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDR------DEEEMTKRDDKRDINRYCKERPS 908
K + ETE D ++ E E D E DR + + T R+ +R+ +R + +
Sbjct: 180 QK-ERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD 238
Query: 909 KDKEKEK 915
+D+ KE+
Sbjct: 239 RDRGKER 245
Score = 56.6 bits (135), Expect = 1e-07
Identities = 33/135 (24%), Positives = 71/135 (52%), Gaps = 11/135 (8%)
Query: 795 EKEDKKEKDKK----SKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDK 850
E++ +EK +K +K +R+ +++E++ + + K+ + D+++++ + ++ D+
Sbjct: 80 ERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDR 139
Query: 851 RKDDSKDDDETEEDNNQDEYDPMEAEEAEDE-EDDRDEEEMTKRDDKRDINRYCKERPSK 909
++ +D D +E Q E D E E E E DR+ E+ +R+ +RD +R +
Sbjct: 140 GRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR------QR 193
Query: 910 DKEKEKTQMITINRD 924
D EKE+ + RD
Sbjct: 194 DTEKERERQTDRERD 208
Score = 52.0 bits (123), Expect = 3e-06
Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 14/128 (10%)
Query: 805 KSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDK--RKDDSKDDDETE 862
++ KD D ++ D E K R D+D+K DR+ R+KE + R D + E E
Sbjct: 67 QAHKDADGDDRQRERDRVREKTEKER----DRDRKRDRERRRKEKETNRNRDREKQTEIE 122
Query: 863 EDNNQDEYDPMEAEEAEDEEDDRDE------EEMTKRDDKRDINRYCKERPSKDKEKEKT 916
D +++ E E E +RD E T++D RD R + +D+E+EK
Sbjct: 123 RDREREKQKGRERERDRGRERERDRDREKERERQTEKD--RDGQRETETERERDREREKQ 180
Query: 917 QMITINRD 924
+ RD
Sbjct: 181 KERETERD 188
Score = 48.5 bits (114), Expect = 4e-05
Identities = 52/245 (21%), Positives = 93/245 (37%), Gaps = 58/245 (23%)
Query: 605 RKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN---------------DLRKELE 649
R++ + E+D + K D E + T+ ++ K ++ D +E E
Sbjct: 85 REKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERE 144
Query: 650 SRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQ 709
K + Q Q + E ++E +E EK ++ E E D + D ++E ER+
Sbjct: 145 RDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTD 204
Query: 710 EEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSL 769
E +RQR+ + + + E ++E E
Sbjct: 205 RERDRQRKTQ---------------------------------TERQRETDREGERETDR 231
Query: 770 FAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKR 829
E RD G + D+KE+ KK +K ERK +++E+ E + K+
Sbjct: 232 RRE---RQRDRDRG-------KERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Query: 830 RKSGD 834
RK G+
Sbjct: 282 RKWGE 286
Score = 44.7 bits (104), Expect = 5e-04
Identities = 22/52 (42%), Positives = 30/52 (57%)
Query: 303 GRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
GR D+ R+ DR RE+ERER+ ++R QR+ ER RERE+ R
Sbjct: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
Score = 44.7 bits (104), Expect = 5e-04
Identities = 21/53 (39%), Positives = 30/53 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R D+ R+ + RER+RER + +ER +R R R+R +ERER R R
Sbjct: 155 RQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRER 207
Score = 44.3 bits (103), Expect = 7e-04
Identities = 21/51 (41%), Positives = 29/51 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R D+ R+ DR RER+R+R R +ER +R R ER R++ER R
Sbjct: 217 RQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKER 267
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/125 (19%), Positives = 61/125 (48%), Gaps = 3/125 (2%)
Query: 599 EKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGL 658
E+ + K+ DG+++ E + + + + ++ D + + +E ++ +
Sbjct: 152 ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQR 211
Query: 659 KSQLIARLTKQLKVEEQKEEQKELEKSE---KEEDEDDDRKSEDDKEEEERKRQEEIERQ 715
K+Q + + E + + ++E ++ KE D + DRK E KE ++ +++E E++
Sbjct: 212 KTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKK 271
Query: 716 RRERR 720
+ E+R
Sbjct: 272 KEEKR 276
Score = 41.6 bits (96), Expect = 0.004
Identities = 20/50 (40%), Positives = 29/50 (58%)
Query: 307 RGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R ++ NR DR ++ E ER R RE+ R+R R+R RER+R + R
Sbjct: 104 RKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKER 153
Score = 41.6 bits (96), Expect = 0.004
Identities = 20/52 (38%), Positives = 30/52 (57%)
Query: 305 NDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
N D+ + +R RERE+++ R RER R+R R+R +ERER + R
Sbjct: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDR 161
Score = 41.2 bits (95), Expect = 0.006
Identities = 16/47 (34%), Positives = 31/47 (65%)
Query: 308 GDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
G++ +R+ +R R+R+R + R RER + +R +ER R++ER ++
Sbjct: 225 GERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKK 271
Score = 40.8 bits (94), Expect = 0.007
Identities = 31/132 (23%), Positives = 62/132 (46%), Gaps = 12/132 (9%)
Query: 591 RGYKQQLVEKLQGERKEADGEQDEE-EKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELE 649
R K++ + + K+ + E+D E EK G +E D + D +E E
Sbjct: 102 RRRKEKETNRNRDREKQTEIERDREREKQKGRERE---------RDRGRERERDRDREKE 152
Query: 650 SRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKS-EKEEDEDDDRKSEDDKEEEERKR 708
+ K Q ++ E +K++++E E+ +++ D + +R+ + D+E + R+R
Sbjct: 153 RERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD-RQR 211
Query: 709 QEEIERQRRERR 720
+ + ERQR R
Sbjct: 212 KTQTERQRETDR 223
Score = 39.7 bits (91), Expect = 0.017
Identities = 18/51 (35%), Positives = 30/51 (58%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R+ + + R+ DR RE+++ER R+R QR +ER + +RER +R
Sbjct: 161 RDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQR 211
Score = 39.7 bits (91), Expect = 0.017
Identities = 17/51 (33%), Positives = 30/51 (58%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R+ ++ R+ +R R+R+R+ + RER R+R R+R + ER+R R
Sbjct: 173 RDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
Score = 39.7 bits (91), Expect = 0.017
Identities = 20/54 (37%), Positives = 28/54 (51%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R D+ R ++ RER+ +R R R+R Q +R RE ERE RR R+
Sbjct: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ 236
Score = 38.9 bits (89), Expect = 0.028
Identities = 18/53 (33%), Positives = 30/53 (56%)
Query: 302 SGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
+ RN ++ + DR RE+++ R R R+R +R+R R+R RER+ R
Sbjct: 109 TNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDR 161
Score = 38.9 bits (89), Expect = 0.028
Identities = 16/41 (39%), Positives = 26/41 (63%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R DR +ER+RER R ER +RK+ R++ + +++ RR
Sbjct: 237 RDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
Score = 38.5 bits (88), Expect = 0.037
Identities = 16/36 (44%), Positives = 24/36 (66%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERE 349
R+ + RERER+R R RER R++ RER ++R+
Sbjct: 127 REKQKGRERERDRGRERERDRDREKERERQTEKDRD 162
Score = 38.5 bits (88), Expect = 0.037
Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSR--ERSPRRERERSPRRVRR 357
R+ DR RERER+R R +ER Q ++ R +R ERER R ++
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
Score = 38.5 bits (88), Expect = 0.037
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 293 RRLDPPSRFSGRNDRG-DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERS 351
R+ D + DR D+ + +R RE +RE R +R +R+R R+R R+RER
Sbjct: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERD 250
Query: 352 PRRVRR 357
+ R+
Sbjct: 251 RKEERK 256
Score = 38.1 bits (87), Expect = 0.048
Identities = 19/53 (35%), Positives = 30/53 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R+ ++ R+ +R R RERER R RE+ +R+ ++R +RE E R R
Sbjct: 123 RDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDR 175
Score = 37.7 bits (86), Expect = 0.063
Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 11/62 (17%)
Query: 306 DRGDQVPNRKDDRSRERERERRR-------SRERSPQ----RKRSRERSPRRERERSPRR 354
DR + ++ DR R+R+RERRR +R+R Q R R RE+ RERER R
Sbjct: 82 DRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGR 141
Query: 355 VR 356
R
Sbjct: 142 ER 143
Score = 37.7 bits (86), Expect = 0.063
Identities = 16/54 (29%), Positives = 32/54 (59%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R ++ +R+ ++ +ERE ER R R+R +++R R+ R+R+R + R+
Sbjct: 165 RETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQ 218
Score = 37.4 bits (85), Expect = 0.083
Identities = 32/138 (23%), Positives = 64/138 (46%), Gaps = 18/138 (13%)
Query: 599 EKLQGERKEADGEQDEE-----EKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRAL 653
E+ +G +E D ++++E EKD +E T + + + K + ++ + +
Sbjct: 136 ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDR-EREKQKERETERDRDRQRD 194
Query: 654 SSKGLKSQLIARLTKQLKV--EEQKEEQKELEKS---EKEEDEDDDRKSEDDKEEE---- 704
+ K + Q +Q K E Q+E +E E+ +E D DR E D+E +
Sbjct: 195 TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
Query: 705 ---ERKRQEEIERQRRER 719
ERK++ + ER+ +++
Sbjct: 255 RKKERKKERKKERKEKKK 272
Score = 37.4 bits (85), Expect = 0.083
Identities = 14/42 (33%), Positives = 26/42 (61%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
+R +R RER+R+ R +ER +RK+ R+ + E+ R ++
Sbjct: 240 DRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Score = 37.0 bits (84), Expect = 0.11
Identities = 21/42 (50%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
Query: 316 DDRSRERERERRRS-RERSPQRKRSRERSPRRERERSPRRVR 356
DDR RER+R R ++ +ER RKR RER R+E+E + R R
Sbjct: 75 DDRQRERDRVREKTEKERDRDRKRDRERR-RKEKETNRNRDR 115
Score = 35.8 bits (81), Expect = 0.24
Identities = 17/53 (32%), Positives = 31/53 (58%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
+ DR + ++ +R+R+RE++ R+R ++++ RER R RER R R
Sbjct: 97 KRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDR 149
Score = 35.8 bits (81), Expect = 0.24
Identities = 16/50 (32%), Positives = 27/50 (54%)
Query: 308 GDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
G + + +R RERE+++ R ER R+R E+ R+ +R R R+
Sbjct: 163 GQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRK 212
Score = 35.8 bits (81), Expect = 0.24
Identities = 17/44 (38%), Positives = 25/44 (56%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R+ + RE ERE R RER R R +ER R+R+ ++ R+
Sbjct: 217 RQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERK 260
Score = 34.7 bits (78), Expect = 0.54
Identities = 25/110 (22%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Query: 604 ERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLI 663
++KE + E+D + + D E + KT + E + + + Q
Sbjct: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD 238
Query: 664 ARLTKQLKVE-EQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEI 712
K+ E ++KEE+K+ K E++++ + +K E +E+++RK E I
Sbjct: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGI 288
Score = 34.7 bits (78), Expect = 0.54
Identities = 19/53 (35%), Positives = 26/53 (49%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R+ + D R+ RER+R+R+ ER + R ER R RER R R
Sbjct: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241
Score = 34.7 bits (78), Expect = 0.54
Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 3/45 (6%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERER 350
DRG + R +R R+ ER++ R +ER +RK ++ RRE ++
Sbjct: 240 DRGKE---RDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Score = 33.9 bits (76), Expect = 0.91
Identities = 13/51 (25%), Positives = 30/51 (58%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R + D+ ++ DR R+R+ ER++ R++ +++R ++ + RE R+
Sbjct: 233 RERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 33.5 bits (75), Expect = 1.2
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Query: 315 KDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
KD +R+RER R RE++ +++R R+R RER R + R
Sbjct: 70 KDADGDDRQRERDRVREKT-EKERDRDRKRDRERRRKEKETNR 111
Score = 33.5 bits (75), Expect = 1.2
Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 305 NDRGDQVPNRKDDRSRERERERRRSRERSPQRK---RSRERSPRRERERSPRRVRR 357
+DR + ++ +ER+R+R+R RER + K R+R+R + E ER R ++
Sbjct: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQ 130
>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
isoform 1 [Homo sapiens]
Length = 483
Score = 72.4 bits (176), Expect = 2e-12
Identities = 73/272 (26%), Positives = 133/272 (48%), Gaps = 29/272 (10%)
Query: 647 ELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEER 706
E ++R L +K L KQ EE++EE++ E K + E++ RK KEEE+R
Sbjct: 186 EAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKW---KEEEKR 242
Query: 707 KRQEEIERQRRER---RYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEH 763
KR++ + ++ +R R L DEP I VH +F ++ LL + +++
Sbjct: 243 KRKDIEKLKKIDRIPERDKLKDEPKIKVH--------RFLLQAVNQKNLLKKPEKGDEKE 294
Query: 764 SFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDE----RKDKKEERD 819
+ +L E L + R +LP++ D + KD+K K+ E R ++ ER+
Sbjct: 295 LDKREKAKKLDKENLSDE---RASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERERE 351
Query: 820 DETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDE--TEEDNNQDEYDPMEAEE 877
E D+ + R + + ++E R ++++ +K K + ++E E+D +D+ E+ E
Sbjct: 352 YERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTE 411
Query: 878 A-EDEEDDRDEEEMTKRDDKRDINRYCKERPS 908
+ E +EE+ KRD R+ K+RP+
Sbjct: 412 SIGSSEKTEKKEEVVKRDRIRN-----KDRPA 438
Score = 37.7 bits (86), Expect = 0.063
Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 17/106 (16%)
Query: 268 LLQQPQQKAGLLQPPV---RIVSQPQPARRLDPPS----RFSGRN---------DRGDQV 311
LLQ QK L +P + + + + A++LD + R SG++ + D+
Sbjct: 274 LLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEK 333
Query: 312 PNRKDDRSRERERERRRSRERSPQR-KRSRERSPRRERERSPRRVR 356
P R +D S RER R ER +R R RER R+E ER ++ R
Sbjct: 334 PKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKER 379
Score = 33.9 bits (76), Expect = 0.91
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
+ R RE +RE RR RE +R+R ER +E E+ R+
Sbjct: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRK 245
Score = 31.2 bits (69), Expect = 5.9
Identities = 17/68 (25%), Positives = 38/68 (55%), Gaps = 8/68 (11%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRE------RSPRRERERSPRRVRR 357
R ++ ++ R+ +R R+RE ERR+ +E ++++ E R P R++ + +++
Sbjct: 211 REEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIK- 269
Query: 358 VVPRYTVQ 365
V R+ +Q
Sbjct: 270 -VHRFLLQ 276
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 71.2 bits (173), Expect = 5e-12
Identities = 104/531 (19%), Positives = 238/531 (44%), Gaps = 69/531 (12%)
Query: 600 KLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKL----DPKTMKVNDLRKELESRA--L 653
KLQ + + + E+ E + + KE+ +KL + + L KEL+S + L
Sbjct: 225 KLQEKLQLVESEKSEIQLN---VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
Query: 654 SSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK---EEEERKRQE 710
++ +++L RL +Q + + ++E+K E EK +++++ + +++K +EE+ +RQE
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 711 EI-----ERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSF 765
E+ E+ RR+ + E + + + ++ +E +
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK--------------EEKMRRQEEMMW 387
Query: 766 EVS-LFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDE 824
E EL +M +++ +I + E+E +E++K+ +++ + ++EE+ E +E
Sbjct: 388 EKEEKIRELEEKMHEQE---KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 825 P-KPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEED 883
+ + +K ++K ++++ ++E+KR++ + + E+ + Q+E + + E EE
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
Query: 884 DRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEK 943
R +EE R +++ + K R ++K + + I ++ + + EK
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEK 564
Query: 944 DLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESL---QEDML 1000
E+ ++ + K+ +E +R+ + EE +E E QE+ +
Sbjct: 565 RQEQ----------EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 1001 GNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEE 1060
+ ++++ + + E I M E+ EK+ E E+K+ EE
Sbjct: 615 REQ----EEKIQEQEEKIREQEEKIREQEEMTQ--------EQEEKM-GEQEEKMCEQEE 661
Query: 1061 KTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQM 1111
K E E+T+ E ++RE +K + + +E ++ E M + E +M
Sbjct: 662 KMQEQEETMWRQEE-------KIREQEKKIREQEEKIREQEEMMQEQEEKM 705
Score = 70.9 bits (172), Expect = 7e-12
Identities = 78/357 (21%), Positives = 170/357 (47%), Gaps = 28/357 (7%)
Query: 575 DVWHCLPTRSEWETLSRGYK-QQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSK 633
++W+ L + E + + K Q+ EK+Q E++E EQ+E+ ++ E W K
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
Query: 634 LDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQ-KELEKSEKEED-- 690
+ K + ++ E E + + + + ++ +Q ++ +KEE+ +ELE+ E++
Sbjct: 348 -EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 406
Query: 691 -EDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSL 749
E ++++ E++K E+ KRQE+ + R+ I E I K + + I
Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK---KMWRQEEKIHEQ 463
Query: 750 SVLLDYRLEDNKEHSFEVSLFAELFNE----------MLQRDFGVRIYKSLLSLPEKEDK 799
+ R E+ ++ E+ E +E M +++ +R + + E++ +
Sbjct: 464 EKI---REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIR 520
Query: 800 KEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDD 859
++++K +++E+ ++EE+ E +E + K + + E+ +++EDK +
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 860 ETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDK-RDINRYCKERPSKDKEKEK 915
E EE + E E EE E+ EE+M K+++K R+ +E+ K +E+E+
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQ----EEKMWKQEEKIREQEEKIQEQEEKIREQEE 633
Score = 68.9 bits (167), Expect = 3e-11
Identities = 130/634 (20%), Positives = 264/634 (41%), Gaps = 81/634 (12%)
Query: 551 HRPEETHKG---------RTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKL 601
H PE+ K R + A V T+ + C T + ++ Y Q V++L
Sbjct: 105 HSPEDEQKASHQHQEALRRELEAQVHTIRILT-----CQKTELQ---MALYYSQHAVKQL 156
Query: 602 QGERKEADGEQDEEEKDDGEAKEI--STPTHWSKLDPKTMKVNDLRKELESRALSSKGLK 659
+GE ++ + K GE ++ + T K D + +L KE ++ +L
Sbjct: 157 EGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD---RYIEELTKERDALSLE----- 208
Query: 660 SQLIARLTKQLKVEEQKEEQKEL-EKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRE 718
+ R T + EE KE+ +L EK + E E + E + +E++R+
Sbjct: 209 ---LYRNT--ITDEELKEKNAKLQEKLQLVESE----------KSEIQLNVKELKRKLER 253
Query: 719 RRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEML 778
+ +LP + A++ + S+S L ++E+N+ + L + +M
Sbjct: 254 AKLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWN---RLNQQQEEKMW 303
Query: 779 QRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDK 838
+++ ++ ++ + E++ +++++K +++E+ ++EE E +E ++ + +K++
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 839 KEDRDER---KKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDD 895
K R E +KE+K + + E EE + E E E+ ++E+ R EEE + +
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 896 KRDINRY--------CKERPSKDKEKEKT-----QMITINRDLLMAFVYFDQSHCGYLLE 942
KR +E+ K +E+EK + I + +Q E
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483
Query: 943 K--DLEEILYTLG-LHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEEN---HEESESLQ 996
K + EEI +H +++K KV +E + + EE EE Q
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 543
Query: 997 EDMLGNRLLL-PTPTVKQESKDVEENVGLIVYNGAMVD----VGSLLQKLEKSEKVRAEV 1051
E+M + + +E K E+ + + + V +K+ + E+ R E
Sbjct: 544 EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603
Query: 1052 EQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQM 1111
E+K+ EEK E E+ I E + ++RE ++ + +E + E + E +M
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 663
Query: 1112 NKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
+ + ++I KK + E+K ++ +E
Sbjct: 664 QEQEETMWRQEEKIREQEKKIR-EQEEKIREQEE 696
Score = 61.2 bits (147), Expect = 5e-09
Identities = 62/329 (18%), Positives = 148/329 (44%), Gaps = 50/329 (15%)
Query: 599 EKLQGERK--EADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSK 656
EK+ + K E + Q++EE E K W + + + +RK+ E +
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517
Query: 657 GLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE---DDDRKSEDDKEEEERKRQEEIE 713
++ Q + K+ EQ+E+ E+ +E++E ++++ E +K EE KRQE+ +
Sbjct: 518 KIREQ-------EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 714 RQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAEL 773
+ R+ I E + W + R ++ K E
Sbjct: 571 KMWRQEEKIREQEEKV-----WRQEE--------------KIREQEEKRQEQE------- 604
Query: 774 FNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSG 833
+M +++ +R + + +++++K ++++ K E+++ +E++++ E + K +
Sbjct: 605 -EKMWKQEEKIREQEEKI---QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
Query: 834 DDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEE--------AEDEEDDR 885
+ ++E+ R++E R+ + K ++ E+ Q+E + E+ E EE +
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
Query: 886 DEEEMTKRDDKRDINRYCKERPSKDKEKE 914
++EE +R +++ + + R ++K +E
Sbjct: 721 EQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 60.1 bits (144), Expect = 1e-08
Identities = 64/347 (18%), Positives = 161/347 (46%), Gaps = 46/347 (13%)
Query: 593 YKQQLVEKLQGERKEADGEQDEEEKDDGEAK-----------EISTPTHWSKLDPKTMKV 641
++Q+ + + + +R+E + +++E++ + EAK E K+ + K+
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 642 NDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK 701
++ K E + + ++ +Q ++ QKE+ E E+ ++++E R+ E +
Sbjct: 461 HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIR 520
Query: 702 EEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNK 761
E+EE+ R++E + R+E + +E W + + + E+ K
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEM-------WREEEKMHEQEKI---------WEEEK 564
Query: 762 EHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKK-EKDKKSKKDERK-----DKK 815
E ++ + E R+ ++++ + E+E+K+ E+++K K E K +K
Sbjct: 565 RQEQEDKMWRQ---EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Query: 816 EERDDETDEPKPKRRK----SGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYD 871
+E++++ E + K R+ + + ++K +++E+ E + K +++ ++ E
Sbjct: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE-- 679
Query: 872 PMEAEEAEDEEDDRDEEEMTKRDDKR---DINRYCKERPSKDKEKEK 915
E + E EE R++EEM + +++ + C++ +++EK
Sbjct: 680 -QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Score = 37.7 bits (86), Expect = 0.063
Identities = 66/391 (16%), Positives = 147/391 (37%), Gaps = 69/391 (17%)
Query: 804 KKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEE 863
K++++ + + KE+ D + P + D KK+ + E ++ ++
Sbjct: 53 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 112
Query: 864 DNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINR 923
++Q + EA E E +T + + + Y + K E E +I+
Sbjct: 113 ASHQHQ----EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS--- 165
Query: 924 DLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQ--VKKLLNKVVLRESCFYRKLTD 981
+ H + +LE+ L + +A +++L + R++ +
Sbjct: 166 ----------RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE---RDALSLELYRN 212
Query: 982 TSKDEENHEESESLQEDML---------------------GNRLLLPTPTVKQESKDVEE 1020
T DEE E++ LQE + +LLLP ++ E+ + +
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 272
Query: 1021 NVGLIVYN-GAMVDVGSLLQKLEKSEKVRA---------------EVEQKLQLLEEKTDE 1064
+ + A V+ L +L + ++ + E E+K++ EEK E
Sbjct: 273 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 1065 DEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNK----------T 1114
E+ + E ++R ++ + + +E ++ E M + E +M +
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Query: 1115 IRNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
IR L M E + +++ + E++ + +E
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 71.2 bits (173), Expect = 5e-12
Identities = 99/511 (19%), Positives = 204/511 (39%), Gaps = 73/511 (14%)
Query: 668 KQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRER-------- 719
++ ++ QK E+ LE +DD + E +E R RQE + +++ E
Sbjct: 6 RRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQ 65
Query: 720 -----RYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELF 774
+ +PDE A N + + L+ R E+ ++ + +L
Sbjct: 66 VEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLA-----RREERRQKRLQEAL----- 115
Query: 775 NEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGD 834
Q++F I + LSLP + + + +++ E+++K E R + + + +
Sbjct: 116 --ERQKEFDPTITDASLSLPSRRMQND-TAENETTEKEEKSESRQERYEIEETETVTKSY 172
Query: 835 DKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAE---EAEDE---------- 881
K+ D +E KKEDK K++ +++ +++ + M E E+++E
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQ 232
Query: 882 ---EDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCG 938
E+ + EEE + D+ + +E + E E+ ++ R+ + A
Sbjct: 233 ISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKA---------- 282
Query: 939 YLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENH--EESESLQ 996
E+D + + RA+++ + + ++EE EE + ++
Sbjct: 283 ---EQDKK-------IADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIK 332
Query: 997 EDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQ 1056
E+ R +K+E K E I + E+ EK + E +++ +
Sbjct: 333 EE--EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNK 390
Query: 1057 LLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIR 1116
LEEK ++T + E + + G+ KK QE+ + + Q E + K ++
Sbjct: 391 QLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK----AQEDKLQTAVLKKQGEEKGTK-VQ 445
Query: 1117 NLSTVMDEIHTVLKKDNVKNE--DKDQKSKE 1145
+ E KK+ +K+E KD++ KE
Sbjct: 446 AKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476
Score = 66.2 bits (160), Expect = 2e-10
Identities = 65/282 (23%), Positives = 136/282 (48%), Gaps = 27/282 (9%)
Query: 641 VNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSE---KEEDEDDDRKS 697
+ D L SR + + +++ T++ + E ++E+ E+E++E K ++D R +
Sbjct: 125 ITDASLSLPSRRMQNDTAENET----TEKEEKSESRQERYEIEETETVTKSYQKNDWRDA 180
Query: 698 EDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSL-----SVL 752
E++K+E++ K +EE E+ +R I ++ ++V + + +MSL S
Sbjct: 181 EENKKEDKEKEEEEEEKPKRGS--IGENQVEVMVEEK--TTESQEETVVMSLKNGQISSE 236
Query: 753 LDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDER- 811
+ E+ ++ S E+S ++ E +R ++ L E+E K + K DER
Sbjct: 237 EPKQEEEREQGSDEISHHEKMEEEDKER---AEAERARLEAEERERIKAEQDKKIADERA 293
Query: 812 ----KDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQ 867
++K ++ E E + + R ++K E+R K+E+KR + + + EE
Sbjct: 294 RIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 353
Query: 868 DEYDPMEAEE---AEDEEDDRDEEEMTKRDDKRDINRYCKER 906
+E ++ EE AE+ + R EEE + +++ N+ +E+
Sbjct: 354 EERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Score = 57.8 bits (138), Expect = 6e-08
Identities = 98/455 (21%), Positives = 189/455 (41%), Gaps = 50/455 (10%)
Query: 585 EWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDD------GEAK-EISTPTHWSKLDPK 637
E ET+++ Y++ + +KE D E++EEE++ GE + E+ ++ +
Sbjct: 164 ETETVTKSYQKNDWRDAEENKKE-DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEE 222
Query: 638 TMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKS 697
T+ ++ ++ S + + Q ++ K+EE+ +E+ E E++ E +E + K+
Sbjct: 223 TVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKA 282
Query: 698 EDDK-----------------EEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSG 740
E DK +E ER+ EE ER R E + + I AA+
Sbjct: 283 EQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEER 342
Query: 741 KFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEK---- 796
+ + R+++ ++ + E A E + V K L EK
Sbjct: 343 QRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAK---VEEQKRNKQLEEKKHAM 399
Query: 797 -EDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKK-EDRDERKKEDK---R 851
E K + +K +K E K E++ E +K G++K K + + E+ +EDK +
Sbjct: 400 QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFK 459
Query: 852 KDDSKDDDETEEDNNQDEYDP-MEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKE--RPS 908
K++ KD+ ++ ++E M+ ++ E ++ E MT + K N + + R S
Sbjct: 460 KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHK-LKHTENTFSRPGGRAS 518
Query: 909 KD-KEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEI---LYTLGLHLSRAQVKKL 964
D KE E + + L + G ++ E++ L L + K+
Sbjct: 519 VDTKEAEGAPQVEAGKRLEEL-----RRRRGETESEEFEKLKQKQQEAALELEELKKKRE 573
Query: 965 LNKVVLRESCFYRKLTDTSKDEENHEESESLQEDM 999
+ VL E RK + + EE L+E++
Sbjct: 574 ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEI 608
Score = 48.1 bits (113), Expect = 5e-05
Identities = 62/272 (22%), Positives = 126/272 (46%), Gaps = 27/272 (9%)
Query: 604 ERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLI 663
ER+ A E++E+ K + + + + +K + +++E + ++ K + +
Sbjct: 369 ERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKL 428
Query: 664 --ARLTKQ-----LKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEE-------RKRQ 709
A L KQ KV+ ++E+ +E + + K+E+ D++ +D + +EE +K
Sbjct: 429 QTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGF 488
Query: 710 EEIERQRRE-RRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVS 768
E++ Q E + L P A + + V RLE+ + E
Sbjct: 489 TEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAE-GAPQVEAGKRLEELRRRRGETE 547
Query: 769 LFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKK-SKKDERKDKKEERDDETDEPKP 827
+E F ++ Q+ ++ L L E + K+E+ +K +++E++ K+EE D + E +
Sbjct: 548 --SEEFEKLKQKQ-----QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 600
Query: 828 KRR-KSGDDKDKKEDRDERKK--EDKRKDDSK 856
KRR K ++ + E ++R+K ED DD K
Sbjct: 601 KRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Score = 47.4 bits (111), Expect = 8e-05
Identities = 70/357 (19%), Positives = 149/357 (41%), Gaps = 63/357 (17%)
Query: 604 ERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGL---KS 660
ER+ EQD++ D+ E + + + + + +E E RA + +
Sbjct: 276 ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE 335
Query: 661 QLIARLTKQLKVEEQK--EEQKELEKSEKEEDEDDDRKSEDDKEE---EERKRQEEIERQ 715
+ A +++K EE++ EE++ +++ EK E+ R +++E+ EE+KR +++E +
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Query: 716 RR--ERRYILPDEPAIIVHPNWA----AKSGKFDCSIMSLS------------------- 750
+ + I ++ + W A+ K +++
Sbjct: 396 KHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDK 455
Query: 751 ------VLLDYRLEDNKEHSFEVSLFAEL---FNEMLQRDFGVRIYK-----SLLSLP-- 794
+ D +++ +KE EV F + F E+ ++ +K + S P
Sbjct: 456 PTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGG 515
Query: 795 -EKEDKKEKDK-------KSKKDERKDKKEERDDETDEPKPKRRKSGDDKDK-KEDRDER 845
D KE + K ++ R+ + E +E ++ K K++++ + ++ K+ R+ER
Sbjct: 516 RASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER 575
Query: 846 KK-----EDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKR 897
+K E +RK + D EE+ + + +E AE E + E DDK+
Sbjct: 576 RKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Score = 44.3 bits (103), Expect = 7e-04
Identities = 49/187 (26%), Positives = 83/187 (44%), Gaps = 28/187 (14%)
Query: 645 RKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSE-KEEDEDDDRKSEDDKEE 703
R E ES K Q A ++LK ++++E +K LE+ E + + E+ DRK + EE
Sbjct: 543 RGETESEEFEKLKQKQQEAALELEELK-KKREERRKVLEEEEQRRKQEEADRKLRE--EE 599
Query: 704 EERKRQEEIERQR---RERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDN 760
E+R+ +EEIER+R E+R +P++ + F C
Sbjct: 600 EKRRLKEEIERRRAEAAEKRQKMPED-------GLSDDKKPFKCF-------------TP 639
Query: 761 KEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDD 820
K S ++ AE N+ +Q+ GV+ ++ K D + + S + K K +
Sbjct: 640 KGSSLKIEERAEFLNKSVQKSSGVKSTHQ-AAIVSKIDSRLEQYTSAIEGTKSAKPTKPA 698
Query: 821 ETDEPKP 827
+D P P
Sbjct: 699 ASDLPVP 705
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 70.9 bits (172), Expect = 7e-12
Identities = 70/337 (20%), Positives = 158/337 (46%), Gaps = 29/337 (8%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKEL-ESRA 652
K + E++ E++E Q+E + E W K + K+ +L +++ E
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE----KIRELEEKMHEQEK 391
Query: 653 LSSKGLKSQLIARLTKQLKVEEQ-----------KEEQKELEKSEKEEDEDDDRKSEDDK 701
+ + K Q ++ +Q K +EQ +E+++++ + EK+ +++ E +K
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 451
Query: 702 EEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNK 761
EE KRQE+ E R+E + +E W K + + +R E+ K
Sbjct: 452 IREEEKRQEQEEMWRQEEKIREQEE-------IWRQKEKMHEQEKIRKQEEKVWRQEE-K 503
Query: 762 EHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDE 821
H E + E +M +++ +R + + E++ +++++ +++E+ ++EE+ E
Sbjct: 504 MHDQEEKI-REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562
Query: 822 TDEPKPKRRKSGDDKDKKEDRDE--RKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEE-- 877
++ + + K + ++K ++ E R++E+K + + E EE + E E EE
Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622
Query: 878 AEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
E EE +++EE +R +++ + + R ++K +E
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 65.5 bits (158), Expect = 3e-10
Identities = 109/589 (18%), Positives = 255/589 (43%), Gaps = 81/589 (13%)
Query: 551 HRPEETHKG---------RTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKL 601
H PE+ K R + A V T+ + C T + ++ Y Q V++L
Sbjct: 105 HSPEDEQKASHQHQEALRRELEAQVHTIRILT-----CQKTELQ---MALYYSQHAVKQL 156
Query: 602 QGERKEADGEQDEEEKDDGEAKEI--STPTHWSKLDPKTMKVNDLRKELESRALSSKGLK 659
+GE ++ + K GE ++ + T K D + +L KE ++ +L
Sbjct: 157 EGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD---RYIEELTKERDALSLE----- 208
Query: 660 SQLIARLTKQLKVEEQKEEQKEL-EKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRE 718
+ R T + EE KE+ +L EK + E E + E + +E++R+
Sbjct: 209 ---LYRNT--ITDEELKEKNAKLQEKLQLVESE----------KSEIQLNVKELKRKLER 253
Query: 719 RRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEML 778
+ +LP + A++ + S+S L ++E+N+ + L + +M
Sbjct: 254 AKLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWN---RLNQQQEEKMW 303
Query: 779 QRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDK 838
+++ ++ ++ + E++ +++++K +++E+ ++EE E +E ++ + +K++
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 839 KEDRDER---KKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDD 895
K R E +KE+K ++ + E E+ Q+E E + E E+ E +M ++++
Sbjct: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 423
Query: 896 KRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLH 955
K +E+ K +E+EK + + ++ ++ EE+
Sbjct: 424 K------IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR------QEQEEMWRQEEKI 471
Query: 956 LSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQES 1015
+ ++ + K+ +E ++ ++E+ H++ E ++E ++ ++++
Sbjct: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE--EKMWRQEEKIREQE 529
Query: 1016 KDVEENVGLIVYNGAMVD-----VGSLLQKLEKSEKVRA------EVEQKLQLLEEKTDE 1064
+ + E I M+ +G +K+++ EK+R E E+K++ +EK E
Sbjct: 530 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE 589
Query: 1065 DEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNK 1113
E+ I E + ++E ++ + + +E + E + E +M +
Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 638
Score = 58.9 bits (141), Expect = 3e-08
Identities = 92/514 (17%), Positives = 218/514 (42%), Gaps = 88/514 (17%)
Query: 600 KLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKL----DPKTMKVNDLRKELESRA--L 653
KLQ + + + E+ E + + KE+ +KL + + L KEL+S + L
Sbjct: 225 KLQEKLQLVESEKSEIQLN---VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
Query: 654 SSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK---EEEERKRQE 710
++ +++L RL +Q + + ++E+K E EK +++++ + +++K +EE+ +RQE
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 711 EIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLF 770
E+ ++ E ++ +E +E
Sbjct: 342 EMMWEKEE-------------------------------------KMRRQEEMMWEKEEK 364
Query: 771 AELFNEMLQRDFGVRIYKSLLSLPEKEDK-KEKDKKSKKDER-KDKKEERDDETDEPKPK 828
EM+ EKE+K +E ++K + E+ ++++E+R +E + +
Sbjct: 365 MRRLEEMMW---------------EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 409
Query: 829 RRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEE 888
+R+ + K +++ R++E+K ++ K EE ++ E E + E EE R EE
Sbjct: 410 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 469
Query: 889 EMTKRDD----KRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKD 944
++ ++++ K ++ K R ++K + + + + + +Q + E+
Sbjct: 470 KIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR-----EQEEKMWRQEEK 524
Query: 945 LEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRL 1004
+ E ++++ K+ +E + + EE +E E ++ ++
Sbjct: 525 IRE---------QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ--EEKI 573
Query: 1005 LLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDE 1064
++++ + + E I + + +++ E+ E E+K+ EEK E
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQE--EMMQEQEEKMWEQEEKMCEQEEKMQE 631
Query: 1065 DEKTILNLENSNKSLSGELREVKKDLSQLQENLK 1098
E+ + E LR+ ++ + + QE+L+
Sbjct: 632 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 46.6 bits (109), Expect = 1e-04
Identities = 67/377 (17%), Positives = 147/377 (38%), Gaps = 55/377 (14%)
Query: 804 KKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEE 863
K++++ + + KE+ D + P + D KK+ + E ++ ++
Sbjct: 53 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 112
Query: 864 DNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINR 923
++Q + EA E E +T + + + Y + K E E +I+
Sbjct: 113 ASHQHQ----EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS--- 165
Query: 924 DLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQ--VKKLLNKVVLRESCFYRKLTD 981
+ H + +LE+ L + +A +++L + R++ +
Sbjct: 166 ----------RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE---RDALSLELYRN 212
Query: 982 TSKDEENHEESESLQEDML---------------------GNRLLLPTPTVKQESKDVEE 1020
T DEE E++ LQE + +LLLP ++ E+ + +
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 272
Query: 1021 NVGLIVYN-GAMVDVGSLLQKLEKSEKVRA-EVEQKLQLLEEKTDEDEKTILNLENSNKS 1078
+ + A V+ L +L + ++ + E+K+Q EEK E E+ I E +
Sbjct: 273 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 1079 LSGELREVKKDLSQLQENLKISENMNLQFENQMNK----------TIRNLSTVMDEIHTV 1128
++R ++ + + +E ++ E M + E +M + IR L M E +
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392
Query: 1129 LKKDNVKNEDKDQKSKE 1145
+++ + E++ + +E
Sbjct: 393 REQEEKRQEEEKIREQE 409
Score = 32.0 bits (71), Expect = 3.5
Identities = 22/117 (18%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 1034 VGSLLQKLEKSEKVRAEVEQKLQ----LLEEKTDEDEKTILNLENSNKSLSGELREVKKD 1089
+ L +K+ + EK+R + E++ + +EK E E + E + ++RE +K
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438
Query: 1090 LSQLQENLKISENMNLQFENQMNKTI-RNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
+ + +E + E + + + Q + + R + ++ +K+ + ++K +K +E
Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE 495
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 70.9 bits (172), Expect = 7e-12
Identities = 110/576 (19%), Positives = 250/576 (43%), Gaps = 85/576 (14%)
Query: 551 HRPEETHKG---------RTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKL 601
H PE+ K R + A V T+ + C T + ++ Y Q V++L
Sbjct: 166 HSPEDEQKASHQHQEALRRELEAQVHTIRILT-----CQKTELQ---MALYYSQHAVKQL 217
Query: 602 QGERKEADGEQDEEEKDDGEAKEI--STPTHWSKLDPKTMKVNDLRKELESRALSSKGLK 659
+GE ++ + K GE ++ + T K D + +L KE ++ +L
Sbjct: 218 EGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD---RYIEELTKERDALSLE----- 269
Query: 660 SQLIARLTKQLKVEEQKEEQKEL-EKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRE 718
+ R T + EE KE+ +L EK + E E + E + +E++R+
Sbjct: 270 ---LYRNT--ITDEELKEKNAKLQEKLQLVESE----------KSEIQLNVKELKRKLER 314
Query: 719 RRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEML 778
+ +LP + A++ + S+S L ++E+N+ + L + +M
Sbjct: 315 AKLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWN---RLNQQQEEKMW 364
Query: 779 QRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDK 838
+++ ++ ++ + E++ +++++K +++E+ ++EE E +E ++ + +K++
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 839 KEDRDER---KKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDD 895
K R E +KE+K ++ + E E+ Q+E E + E E+ E +M ++++
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 896 KRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLH 955
K R +E+ + +EK Q I+ + Q + + E+I +
Sbjct: 485 KI---REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIW 539
Query: 956 LSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQES 1015
+ ++ + K+ +E +R+ +E+ H++ E ++E ++ ++++
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQ------EEKMHDQEEKIREQE--EKVWRQEEKIREQE 591
Query: 1016 KDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENS 1075
+ + E +K+ + E++ E E+K+ EEK E E+ + E
Sbjct: 592 EKIREQE----------------EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK 635
Query: 1076 NKSLSGELREVKKDLSQLQENLKISENMNLQFENQM 1111
+ ++RE +K + + +E ++ E M + E +M
Sbjct: 636 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Score = 63.5 bits (153), Expect = 1e-09
Identities = 98/514 (19%), Positives = 219/514 (42%), Gaps = 93/514 (18%)
Query: 600 KLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKL----DPKTMKVNDLRKELESRA--L 653
KLQ + + + E+ E + + KE+ +KL + + L KEL+S + L
Sbjct: 286 KLQEKLQLVESEKSEIQLN---VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 342
Query: 654 SSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK---EEEERKRQE 710
++ +++L RL +Q + + ++E+K E EK +++++ + +++K +EE+ +RQE
Sbjct: 343 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 402
Query: 711 EIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLF 770
E+ ++ E+ M + + E+ E+
Sbjct: 403 EMMWEKEEK---------------------------MRRQEEMMWEKEEKMRRQEEM--- 432
Query: 771 AELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRR 830
M +++ +R E E+K + +K ++ E K ++EE+ E ++ + +
Sbjct: 433 ------MWEKEEKIR---------ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Query: 831 KSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEA-EDEEDDRDEEE 889
K ++K +++E+ +E + K +++ E++ ++E E EE EE R++EE
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 537
Query: 890 MTKRDDK----RDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDL 945
+ ++ +K + R +E+ + +EK Q I +Q + E+ +
Sbjct: 538 IWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR----------EQEEKVWRQEEKI 587
Query: 946 EEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENH-EESESLQEDMLGNRL 1004
E ++++ K+ +E + + EE E+ E +QE ++
Sbjct: 588 RE---------QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ--EEKM 636
Query: 1005 LLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDE 1064
++++ K + E I M +++ E+ E E+K+ EEK E
Sbjct: 637 RRQEEKIREQEKKIREQEEKIREQEEM---------MQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 1065 DEKTILNLENSNKSLSGELREVKKDLSQLQENLK 1098
E+ + E LR+ ++ + + QE+L+
Sbjct: 688 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 46.6 bits (109), Expect = 1e-04
Identities = 67/377 (17%), Positives = 147/377 (38%), Gaps = 55/377 (14%)
Query: 804 KKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEE 863
K++++ + + KE+ D + P + D KK+ + E ++ ++
Sbjct: 114 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 173
Query: 864 DNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINR 923
++Q + EA E E +T + + + Y + K E E +I+
Sbjct: 174 ASHQHQ----EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS--- 226
Query: 924 DLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQ--VKKLLNKVVLRESCFYRKLTD 981
+ H + +LE+ L + +A +++L + R++ +
Sbjct: 227 ----------RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE---RDALSLELYRN 273
Query: 982 TSKDEENHEESESLQEDML---------------------GNRLLLPTPTVKQESKDVEE 1020
T DEE E++ LQE + +LLLP ++ E+ + +
Sbjct: 274 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 333
Query: 1021 NVGLIVYN-GAMVDVGSLLQKLEKSEKVRA-EVEQKLQLLEEKTDEDEKTILNLENSNKS 1078
+ + A V+ L +L + ++ + E+K+Q EEK E E+ I E +
Sbjct: 334 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 393
Query: 1079 LSGELREVKKDLSQLQENLKISENMNLQFENQMNK----------TIRNLSTVMDEIHTV 1128
++R ++ + + +E ++ E M + E +M + IR L M E +
Sbjct: 394 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 453
Query: 1129 LKKDNVKNEDKDQKSKE 1145
+++ + E++ + +E
Sbjct: 454 REQEEKRQEEEKIREQE 470
Score = 34.7 bits (78), Expect = 0.54
Identities = 23/118 (19%), Positives = 62/118 (52%), Gaps = 4/118 (3%)
Query: 599 EKLQGERKEADGEQDE---EEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSS 655
E++ E++E GEQ+E E+++ + +E K+ + K+ + +++ +
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Query: 656 KGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIE 713
+ + ++ + K + EE+ +EQ+E + ++E+ + + + +EE+ ++ QE +E
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR-QQEEKMQEHQEHLE 721
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 70.5 bits (171), Expect = 9e-12
Identities = 107/525 (20%), Positives = 224/525 (42%), Gaps = 76/525 (14%)
Query: 601 LQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKS 660
LQ E + E E+EK + +E W + + + +R++ E K L+
Sbjct: 232 LQEEMWRQEEELREQEKKIRKQEE----KMWRQEERLREQEGKMREQEEKMRRQEKRLRE 287
Query: 661 QLIARLTKQLKVEEQK-EEQKELEKSEKEEDEDDDRKSEDDK----EEEERKRQEEI--- 712
Q K+L+ +E++ EQK+L + E++ E +++ E ++ +EE+ RQEE
Sbjct: 288 Q-----EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 342
Query: 713 -ERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFA 771
E+Q RE+ + D+ + W D RL + +E E
Sbjct: 343 QEKQMREQEQKMRDQEERM----WEQ----------------DERLREKEERMREQEKMW 382
Query: 772 ELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRK 831
E +M + + RI + EK+ ++E++ +++E+ K+EE E +E + ++++
Sbjct: 383 EQEEKMQEEE---RIRER-----EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Query: 832 SGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMT 891
+ K+K ++++ ++++++ + ++ +E+ E E+ ++ED E+E
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 892 KRDDKR---DINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEI 948
RD ++ D E+ + +EKE+ +Q EK EE
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMR--------------EQKKMWQQEEKMREEK 540
Query: 949 LYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPT 1008
+ Q +K+ + +RE R+ ++E E+ E +QE R
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMRE----REKKMREEEEMMREQEEKMQEQEEKMR----- 591
Query: 1009 PTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKT 1068
+QE K E+ + M + + + E+ +K++ E E+ + EEK E E+
Sbjct: 592 ---EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ-EQEEMMWEQEEKMQEQEEK 647
Query: 1069 ILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNK 1113
+ E + ++RE ++ + +E ++ E E +M +
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692
Score = 69.7 bits (169), Expect = 2e-11
Identities = 103/531 (19%), Positives = 219/531 (41%), Gaps = 113/531 (21%)
Query: 592 GYKQQLVEKLQGERK---EADGEQDEEEKDDGEAKEISTPTH---------WSKLDPKTM 639
G ++ EK++ + K E + E E+EK+ E K++ W + +
Sbjct: 269 GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328
Query: 640 KVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEED---EDDDRK 696
+ + ++ E K ++ Q ++ ++ EQ E +E E+ +E++ E +++
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388
Query: 697 SEDDK-EEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDY 755
E+++ E E+K +EE E R + + E + W + ++
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENM-----WEQEEKEWQ----------QQ 433
Query: 756 RLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKK 815
RL + KE +E E ++ +++ +R D++E + KK R++K
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIR------------DQEEMWGQEKKMWRQEKM 481
Query: 816 EERDDETDEPKPKRR----KSGDDKDKKEDRDE--RKKEDKRKDDSKDDDETEEDNNQDE 869
E++D+ E + K R K D +++ ++DE R+KE++ ++ K + E+ + +
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK 541
Query: 870 YDPMEAEEAEDEEDDRDEEEMTKRDDK-RDINRYCKERPSKDKEKEKTQMITINRDLLMA 928
E + + EE R+EE M +R+ K R+ +E+ K +E+E+
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR---------- 591
Query: 929 FVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEEN 988
+Q + E+ ++E Q +K+ + E + ++ D +++E
Sbjct: 592 ----EQEEKMWEQEEKMQE------------QEEKMWEQ---EEKMWEQEEEDKMQEQEE 632
Query: 989 --HEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEK 1046
E+ E +QE QE K E+ +K+ + E+
Sbjct: 633 MMWEQEEKMQE---------------QEEKMWEQE-----------------EKMREQEE 660
Query: 1047 VRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENL 1097
E E+K+Q EEK E E+ + E + ++R ++ + +E +
Sbjct: 661 KMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
Score = 65.5 bits (158), Expect = 3e-10
Identities = 108/600 (18%), Positives = 248/600 (41%), Gaps = 99/600 (16%)
Query: 572 FFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHW 631
F ++ L S W + Y ++L ++ E E+ + E+
Sbjct: 139 FAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRL 198
Query: 632 SKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE 691
++ + +++N KEL+ + +K L Q+ T Q ++ Q+EE +E EK ++++E
Sbjct: 199 AESEKSEIQLNV--KELKRKLERAKFLLPQVQTN-TLQEEMWRQEEELREQEKKIRKQEE 255
Query: 692 DDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSV 751
R+ E +E+E + R++E + +R+E+R
Sbjct: 256 KMWRQEERLREQEGKMREQEEKMRRQEKR------------------------------- 284
Query: 752 LLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLS----LPEKEDK--KEKDKK 805
E E+ +++ +R K L + E+E+K ++++K
Sbjct: 285 ------------------LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKM 326
Query: 806 SKKDERKDKKEERDDETDEP-KPKRRKSGDDKDKKEDRDER--KKEDKRKDDSKDDDETE 862
+++E+ ++EER E ++ + + +K D +++ ++DER +KE++ ++ K ++ E
Sbjct: 327 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE 386
Query: 863 EDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITIN 922
+ ++ E + E+EE R++EE ++ ++ + KE + ++K ++
Sbjct: 387 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL---- 442
Query: 923 RDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFY-----R 977
++Q EK E+ Q KK+ + +RE
Sbjct: 443 ---------WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 493
Query: 978 KLTDT------------SKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLI 1025
K+ D +DE E+ E ++E ++ +++E K E+
Sbjct: 494 KMRDQEQKMWDQEERMWEQDERLREKEERMREQ---KKMWQQEEKMREEKKTQEQEKKTW 550
Query: 1026 VYNGAMVDVGSLLQ---KLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGE 1082
M + + + K+ + E++ E E+K+Q EEK E E+ + E + +
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Query: 1083 LREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQK 1142
+ E ++ + + +E K+ E + +E + + ++ M E +++ K ++++K
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQE--EKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Score = 63.2 bits (152), Expect = 1e-09
Identities = 66/353 (18%), Positives = 165/353 (46%), Gaps = 24/353 (6%)
Query: 576 VWHCLPTRSEWETLSRGYKQQLVEKLQGER-KEADGEQDEEEKDDGEAKEISTPTHWSKL 634
+W E E R ++++ E Q ER +E + E+EK + +++ +
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWE--QDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 635 DPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE--D 692
+ K + + +E E + + + + +Q ++ EQKE+ E EK +++E++ +
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457
Query: 693 DDRKSEDDKE---EEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSL 749
+ K D +E +E++ ++E R++ ++ + ++ W + ++
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE------ 511
Query: 750 SVLLDYRLEDNKEHSFEVSLFAELFNEMLQ----RDFGVRIYKSLLSLPEKEDKKEKDKK 805
D RL + +E E + +M + ++ + + + E+E +E++KK
Sbjct: 512 ---QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 806 SKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDN 865
+++E + E++++ E + K R+ + ++E++ + ++E + + K ++ EED
Sbjct: 569 MREEE--EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626
Query: 866 NQDEYDPM-EAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQ 917
Q++ + M E EE E++++ E+ K ++ + R +E+ +EK + Q
Sbjct: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Score = 57.4 bits (137), Expect = 8e-08
Identities = 57/331 (17%), Positives = 149/331 (45%), Gaps = 6/331 (1%)
Query: 586 WETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLR 645
WE + ++QQ + + + + E + Q++EEK + ++I + K + +R
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
Query: 646 KELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEE----DEDDDRKSEDDK 701
++ + + ++ Q ++ ++ EQ E +E E+ +E+ +++ + E
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 702 EEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNK 761
+E+E+K ++ E+ R E R ++ + K + + E +
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Query: 762 EHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDE 821
+ + E +M +++ ++ + + E+E+K + +++ K E+++K E++++
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ-EQEEKMWEQEEKMREQEEK 661
Query: 822 TDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDE 881
E + K + + ++E++ + ++E R+ + K + E+ Q+E + E+ +
Sbjct: 662 MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ 721
Query: 882 EDDRDEEEMTKRDDKRDINRYCKERPSKDKE 912
E+ R++EE RD K + E + E
Sbjct: 722 EEMREKEERI-RDQKEKMQERLPEHEERCSE 751
Score = 57.0 bits (136), Expect = 1e-07
Identities = 113/568 (19%), Positives = 237/568 (41%), Gaps = 66/568 (11%)
Query: 593 YKQQLVEKLQ----GERKEADGEQDEEEKDDGEAKE-ISTPTHWSK-----LDPKTMKVN 642
Y Q K + GE K+ G GE + +S + W K ++ T + +
Sbjct: 110 YSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERD 169
Query: 643 DLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE 702
L EL ++++ LK + A L ++L++ E E+ E++ + KE +R +
Sbjct: 170 ALSLELYRNTITNEELKKKN-AELQEKLRLAES--EKSEIQLNVKELKRKLERAKFLLPQ 226
Query: 703 EEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKE 762
+ QEE+ RQ E R E I R ++ K
Sbjct: 227 VQTNTLQEEMWRQEEELR---EQEKKI--------------------------RKQEEKM 257
Query: 763 HSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKE----DKKEKDKKSKKDERKDKKEER 818
E L E +M +++ +R + L EKE +K+ +++K K E++++ +E+
Sbjct: 258 WRQEERL-REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK-KLREQEEQMQEQ 315
Query: 819 DDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEA 878
+++ E + K R+ + ++E+R +++ R+ + K D+ E QDE
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE------RLR 369
Query: 879 EDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCG 938
E EE R++E+M ++++K +ER K +E+E+T + ++Q
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 429
Query: 939 Y---LLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCF--YRKLTDTSKDEENHEESE 993
+ L + E++ + ++ + K+ +E + +K+ K E ++
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 994 SLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEK--SEKVRAEV 1051
+E M + QE + E++ L M + + Q+ EK EK E
Sbjct: 490 EQEEKMRDQEQKM----WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Query: 1052 EQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQM 1111
E+K EEK E+E+ + E + +RE ++ + + +E ++ E + E +M
Sbjct: 546 EKKTWDQEEKMREEER-MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM 604
Query: 1112 NKTIRNLSTVMDEIHTVLKKDNVKNEDK 1139
+ + +++ ++D ++ +++
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
Score = 54.7 bits (130), Expect = 5e-07
Identities = 68/344 (19%), Positives = 154/344 (44%), Gaps = 38/344 (11%)
Query: 586 WETLSRGYKQQLV---EKLQGERKEADGEQDEE---------EKDDGEAKEISTPTHWSK 633
WE + +++ + EK E +E EQ+E+ E+++ E ++ P K
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Query: 634 L--DPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE 691
L K + + E E + + + Q ++ +Q K+ EQ+++ E E EK D+
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE-KKMWRQEKMREQEDQMWEQE--EKMRDQ 498
Query: 692 DDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSV 751
+ ++++ E+ +R E E + RE++ + E + + K
Sbjct: 499 EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK---------- 548
Query: 752 LLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDER 811
D +E E E +M + + +R + + E+E+K ++++ K E+
Sbjct: 549 -----TWDQEEKMREEERMREREKKMREEEEMMREQEE--KMQEQEEKM-REQEEKMWEQ 600
Query: 812 KDKKEERDDETDEPKPKRRKSGDDKDKKEDRDER--KKEDKRKDDSKDDDETEEDNNQDE 869
++K +E++++ E + K + +++DK ++++E ++E+K ++ + E EE + E
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQ-EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
Query: 870 YDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEK 913
E EE ++++ E+ K + + R +E+ +EK
Sbjct: 660 EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Score = 37.0 bits (84), Expect = 0.11
Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 27/277 (9%)
Query: 884 DRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEK 943
DR EE+TK D + Y R + E+ K + + L +A + L K
Sbjct: 158 DRYIEELTKERDALSLELY---RNTITNEELKKKNAELQEKLRLAESEKSEIQ---LNVK 211
Query: 944 DLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGN- 1002
+L+ L L + Q L ++ +E + K EE E + G
Sbjct: 212 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
Query: 1003 ------------RLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAE 1050
RL ++++ K++ E L M + + E+ EK+R E
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW--EQEEKMR-E 328
Query: 1051 VEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFEN- 1109
E+K+ EE+ E EK + E + + E + L + +E ++ E M Q E
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388
Query: 1110 QMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKEN 1146
Q + IR M E ++ + E+K QK +EN
Sbjct: 389 QEEERIREREKKMREEEETMR----EQEEKMQKQEEN 421
Score = 32.0 bits (71), Expect = 3.5
Identities = 56/310 (18%), Positives = 123/310 (39%), Gaps = 35/310 (11%)
Query: 828 KRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDE 887
K R++ + KK+ D R+ D + ++ NN + +E ED++
Sbjct: 16 KTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKKA 75
Query: 888 EEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEE 947
+ +R+I + + +++T + L +Y+ Q + +L E
Sbjct: 76 SHQHQEALRREI----------EAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGE 125
Query: 948 ILYTLG-LHLS---RAQVKKLLNKVVL---------------RESCFYRKLTDTSKDEEN 988
G LH S ++++ L+ V R++ +T +EE
Sbjct: 126 SKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEEL 185
Query: 989 HEESESLQEDML-----GNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEK 1043
+++ LQE + + + L +K++ + + + + N ++ ++L +
Sbjct: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 1044 SEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENM 1103
EK + E+K+ EE+ E E + E + LRE +K+L + ++ L+ + +
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKL 305
Query: 1104 NLQFENQMNK 1113
Q E QM +
Sbjct: 306 REQ-EEQMQE 314
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 70.1 bits (170), Expect = 1e-11
Identities = 63/269 (23%), Positives = 127/269 (47%), Gaps = 64/269 (23%)
Query: 640 KVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSED 699
++ + +E+E+R K +S E+K+E++E EK ++E ++ +RK E
Sbjct: 37 EIREREREIETRKEGKKERES-------------ERKKERREREKRKREREK--ERKRER 81
Query: 700 DKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLED 759
K+E++ +R++E ER+R++RR R ++
Sbjct: 82 GKKEKKGERKKE-ERERKKRR-----------------------------------REKE 105
Query: 760 NKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKE-DKKEKDKKSKKDERKDKKEER 818
NKE E +R + + S KE ++KE+ K+ ++ ER+ KKEER
Sbjct: 106 NKEG-----------EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 819 DDETDEPKPKRRKSGDDKDKKEDRDER-KKEDKRKDDSKDDDETEEDNNQDEYDPMEAEE 877
+ E + + K+R+ +K+E+R E+ +KE K+++ ++ + + E + + E ++
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 878 AEDEEDDRDEEEMTKRDDKRDINRYCKER 906
E+ + +R ++ T +K R KER
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKER 243
Score = 68.9 bits (167), Expect = 3e-11
Identities = 59/253 (23%), Positives = 119/253 (47%), Gaps = 56/253 (22%)
Query: 674 EQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHP 733
E +E ++E+E ++ + E + + ++ +E E+RKR+ E ER+R +
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK------------- 83
Query: 734 NWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSL 793
K K + R ++NKE E +R
Sbjct: 84 ----KEKKGERKKEERERKKRRREKENKEGE-----------EKEKR------------- 115
Query: 794 PEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKK------ 847
+K++KKE+ + SK+ + +++KEER E E K + RK ++++K+ +R ERKK
Sbjct: 116 -KKKEKKERGRTSKEGKERERKEERKRE--ERKERERKK-EEREKERERKERKKRERKQV 171
Query: 848 ---EDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRD--INRY 902
E++RK+ + + + E N ++ E +E + + +R ++E K++ ++D N
Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWR 231
Query: 903 CKERPSKDKEKEK 915
KER +++++ K
Sbjct: 232 EKERGKRERKERK 244
Score = 68.9 bits (167), Expect = 3e-11
Identities = 41/143 (28%), Positives = 78/143 (54%), Gaps = 20/143 (13%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEER-------DDETDEPKPKRRKS-----------GDDK 836
EKE K+E+ KK KK ERK ++ ER +++ E K KR+K G ++
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 837 DKKEDR--DERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRD 894
++KE+R +ERK+ +++K++ + + E +E ++ E EE E++ ++ ++ +
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
Query: 895 DKRDINRYCKERPSKDKEKEKTQ 917
+R R KER + KE++K +
Sbjct: 194 KERKKERERKERRERKKERKKKE 216
Score = 65.5 bits (158), Expect = 3e-10
Identities = 44/146 (30%), Positives = 79/146 (54%), Gaps = 26/146 (17%)
Query: 795 EKEDKKEKDKKSKKDER--KDKKEERDDETDEPKPKRR----KSGDDKDKKE-------- 840
E+E +K + +K +K ER K+KK ER E E K +RR K G++K+K++
Sbjct: 65 EREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERG 124
Query: 841 ---------DRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMT 891
+R E +K ++RK+ + +E E++ + E E ++ ++E++R E+E
Sbjct: 125 RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184
Query: 892 KRDDKRDINRYCKERPSKDKEKEKTQ 917
+R KR+ NR KER + + KE+ +
Sbjct: 185 ER-KKRERNR--KERKKERERKERRE 207
Score = 65.1 bits (157), Expect = 4e-10
Identities = 35/126 (27%), Positives = 72/126 (57%), Gaps = 5/126 (3%)
Query: 796 KEDKKEKDKKSKKD--ERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKD 853
KE KKE++ + KK+ ER+ +K ER+ E + K+ K G+ K ++ +R +R++E + K+
Sbjct: 49 KEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKE 108
Query: 854 DSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEK 913
+ + +++ + E +E E +E +R EE +R+ K++ KER K+++K
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKE-ERKREERKERERKKEERE--KERERKERKK 165
Query: 914 EKTQMI 919
+ + +
Sbjct: 166 RERKQV 171
Score = 60.5 bits (145), Expect = 9e-09
Identities = 63/265 (23%), Positives = 111/265 (41%), Gaps = 65/265 (24%)
Query: 585 EWETLSRGYKQQLVE--KLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
E ET G K++ E K + ER++ E+++E K + KE + + K +
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 643 DLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE 702
KE E + K K + R +K+ K E+KEE+K E+ E+E RK E+ ++
Sbjct: 104 KENKEGEEKEKRKKKEKKER-GRTSKEGKERERKEERKREERKERE------RKKEEREK 156
Query: 703 EEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKE 762
E ERK ER++RER+ + E E+ KE
Sbjct: 157 ERERK-----ERKKRERKQVGEKE-------------------------------EERKE 180
Query: 763 HSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDET 822
R + KE KKE+++K +++ +K++K++ + +
Sbjct: 181 KE--------------------RKERKKRERNRKERKKERERKERRERKKERKKKEERKK 220
Query: 823 DEPKPKRRKSGDDKDKKEDRDERKK 847
+ K ++ + + K +R ERKK
Sbjct: 221 ERQKDRQTNWREKERGKRERKERKK 245
Score = 59.7 bits (143), Expect = 2e-08
Identities = 29/123 (23%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Query: 796 KEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDS 855
+ +K+ K+ + K+ +K +K+ER + E K + RK ++++++R+ +K+E +++ +
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
Query: 856 KDDDETEEDN-NQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
K+ + E + E + E E E ++ +R+ +E K ++++ KER K++ K+
Sbjct: 161 KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKK 220
Query: 915 KTQ 917
+ Q
Sbjct: 221 ERQ 223
Score = 57.8 bits (138), Expect = 6e-08
Identities = 55/228 (24%), Positives = 111/228 (48%), Gaps = 37/228 (16%)
Query: 668 KQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEP 727
K+ + E+K+E++E EK ++E +++ RK E K+E++ +R++E ER+R++RR +
Sbjct: 52 KKERESERKKERREREKRKREREKE--RKRERGKKEKKGERKKE-ERERKKRRREKEN-- 106
Query: 728 AIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIY 787
K G+ E K E E +R+ +
Sbjct: 107 ----------KEGE----------------EKEKRKKKEKKERGRTSKEGKERER--KEE 138
Query: 788 KSLLSLPEKEDKKE-KDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERK 846
+ E+E KKE ++K+ ++ ERK ++ ++ E +E + K ++ + K ++ +R ERK
Sbjct: 139 RKREERKERERKKEEREKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERK 197
Query: 847 KEDKRKD--DSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTK 892
KE +RK+ + K + + +E+ ++ + E E R+ +E K
Sbjct: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 53.5 bits (127), Expect = 1e-06
Identities = 55/245 (22%), Positives = 111/245 (45%), Gaps = 44/245 (17%)
Query: 611 EQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQL 670
E++ E + +G+ + S + K + + ++ E KG + + R K+
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK-EERERKKR 100
Query: 671 KVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE---EEERKRQEEIERQRRERRYILPDEP 727
+ E++ +E +E EK +K+E ++ R S++ KE +EERKR+E ER+R++ E
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE- 159
Query: 728 AIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIY 787
R E K +V E E +++ R
Sbjct: 160 ----------------------------RKERKKRERKQV---GEKEEERKEKERKERKK 188
Query: 788 KSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKK 847
+ K++++ K+++ +K ERK KKEER K +R+K ++++R +R++
Sbjct: 189 RERNRKERKKERERKERRERKKERK-KKEER-------KKERQKDRQTNWREKERGKRER 240
Query: 848 EDKRK 852
++++K
Sbjct: 241 KERKK 245
Score = 50.8 bits (120), Expect = 7e-06
Identities = 36/141 (25%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
R E E K++ +K + ER E E E+ + +E K + + +
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
Query: 643 DLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE 702
RK+ E + + K + + R ++ + +KE +KE E+ E+ E + + +K E+ K+
Sbjct: 161 KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKK 220
Query: 703 EEERKRQ---EEIERQRRERR 720
E ++ RQ E ER +RER+
Sbjct: 221 ERQKDRQTNWREKERGKRERK 241
Score = 40.4 bits (93), Expect = 0.010
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 279 LQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKR 338
L +++VS ++ P S +R ++ RK+ + +ERE ER++ R +RKR
Sbjct: 13 LNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGK-KERESERKKERREREKRKR 71
Query: 339 SRERSPRRERERSPRRVRR 357
RE+ +RER + ++ R
Sbjct: 72 EREKERKRERGKKEKKGER 90
Score = 40.4 bits (93), Expect = 0.010
Identities = 19/48 (39%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 303 GRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERER 350
GR + + RK++R RE +ER R +E +R++ RER R++RER
Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKE---EREKERERKERKKRER 168
Score = 40.4 bits (93), Expect = 0.010
Identities = 19/52 (36%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERS-PQRKRSRERSPRRERERSPRR 354
R R + K++ +E+ER+ R+ RER+ +RK+ RER RRER++ ++
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Score = 40.0 bits (92), Expect = 0.013
Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 303 GRNDRGDQVPNRKDDRSRERER-ERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
G + + RK+ + RER R ER++ RER +R+R +ER + ER++ ++ R+
Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQ 227
Score = 39.3 bits (90), Expect = 0.022
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 293 RRLDPPSRFSGRNDR-GDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERS 351
R + +R G+ +R ++ R++ R+RERE+ R RER + K+ + RER++
Sbjct: 41 REREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKR 100
Query: 352 PR 353
R
Sbjct: 101 RR 102
Score = 38.5 bits (88), Expect = 0.037
Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 6/60 (10%)
Query: 304 RNDRGDQVPNRKDDRSRERER-----ERRRSRERSPQRKRSRERSPR-RERERSPRRVRR 357
+ + ++ RK+ + RER++ E R+ +ER ++KR R R R +ERER RR R+
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
Score = 38.1 bits (87), Expect = 0.048
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
Query: 286 VSQP--QPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSR--- 340
+S+P QP + + R R + R+ +R +ER +R RER +RKR R
Sbjct: 25 ISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK 84
Query: 341 ERSPRRERERSPRRVRR 357
E+ R++E R+ RR
Sbjct: 85 EKKGERKKEERERKKRR 101
Score = 37.4 bits (85), Expect = 0.083
Identities = 17/53 (32%), Positives = 26/53 (49%)
Query: 305 NDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
N G++ RK +ER R + +ER + +R RE RER++ R R
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Score = 36.6 bits (83), Expect = 0.14
Identities = 20/72 (27%), Positives = 34/72 (47%)
Query: 280 QPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRS 339
Q +R + R+ R S R + RK +R +ER+RER + ++ ++K
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 340 RERSPRRERERS 351
RER RR + +
Sbjct: 95 RERKKRRREKEN 106
Score = 35.8 bits (81), Expect = 0.24
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVV 359
+ ++ ++ K+ + RER+ ER+R ER + ++ ER RER+ +R R+ V
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKR-EERKERERKKEEREKERERKERKKRERKQV 171
Score = 34.3 bits (77), Expect = 0.70
Identities = 15/65 (23%), Positives = 33/65 (50%)
Query: 293 RRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSP 352
R+ + R R ++ ++ K+ R ++ ++ER R+ + +R+R ER +ER
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 353 RRVRR 357
++ R
Sbjct: 150 KKEER 154
Score = 34.3 bits (77), Expect = 0.70
Identities = 19/60 (31%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 303 GRNDRGDQVPNRKDDRSRERER-ERRRSRERSPQRKRSRER-----SPRRERERSPRRVR 356
G+ + R++ + RER++ ER + RER ++KR R++ R+E+ER R+ R
Sbjct: 130 GKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR 189
Score = 33.5 bits (75), Expect = 1.2
Identities = 16/48 (33%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPR 353
+R ++ R+ RER++ER++ ER +R++ R+ + RE+ER R
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTN-WREKERGKR 238
Score = 32.3 bits (72), Expect = 2.7
Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 11/58 (18%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSR-----------ERSPRRERER 350
R R RK +R R+ RER++ R++ +RK+ R ER R +ER
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
Score = 31.6 bits (70), Expect = 4.5
Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 304 RNDRGDQVPNRKDDRSRER---ERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R +R + R+ +R RER E++ R +E ++KR RE+ + E+ R+
Sbjct: 63 RREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116
Score = 30.8 bits (68), Expect = 7.7
Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 314 RKDDRSRERERERR--RSRERSPQRKRSRERSPRRERERSPRR 354
RK+ R R++ER+++ R +ER R+ + R +RER R+
Sbjct: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 70.1 bits (170), Expect = 1e-11
Identities = 76/369 (20%), Positives = 165/369 (44%), Gaps = 41/369 (11%)
Query: 581 PTRSEWETLSRGYKQQLVEKLQGER------------KEADGEQDEEEKDDGEAKEISTP 628
P S ET S G ++ ++ G R K+A E DEE+ + E +
Sbjct: 417 PAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRS 476
Query: 629 THWSKLDPKTMKVNDLR---------KELESRALSSKGLKSQLIARLTKQLKVEEQKEEQ 679
S P + V LR + L + + + + I R T L+++ +++E+
Sbjct: 477 KTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTP-LRMDPKEKER 535
Query: 680 KELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRER-RYILPDEPAIIVHPNWAAK 738
+ LE ++E+ + R+ + EE++R+R EE++ +R ER R +L + K
Sbjct: 536 QRLENLRRKEEAEQLRRQK--VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK 593
Query: 739 SGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKED 798
I +D + E KE L E ++ + + + + ++E+
Sbjct: 594 Q------IEQKFAQIDEKTEKAKEE--------RLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 799 KKEKDKKSKKDERKDKKEERDDETDEPKPKR-RKSGDDKDKKEDRD-ERKKEDKRKDDSK 856
+ + + +++E + + +E + E + +R RK+ + K E R+ ER+++++R+ + +
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
Query: 857 DDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKT 916
+ + E++ + E E E ++E + E E+ +R+ + + +R ++K+K++
Sbjct: 700 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759
Query: 917 QMITINRDL 925
Q R L
Sbjct: 760 QQRLAERQL 768
Score = 48.5 bits (114), Expect = 4e-05
Identities = 56/298 (18%), Positives = 127/298 (42%), Gaps = 53/298 (17%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRAL 653
K++ ++L+ R++ + EQ +K + E K K + + KV R+ +E
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVE-EDKRRRLEEVKLKREERLRKVLQARERVEQMKE 589
Query: 654 SSKGLKSQLIARL---TKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQE 710
K Q A++ T++ K E EE+ + + + K+ +E + R+ K+EEE +R
Sbjct: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR----KQEEEARRLR 645
Query: 711 EIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLF 770
++++ ERR+ LL + E+ +E + +
Sbjct: 646 WLQQEEEERRH----------------------------QELLQKKKEEEQERLRKAAEA 677
Query: 771 AELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRR 830
L + Q E+ +++ ++++ ++ ER++ +E R+ E + +RR
Sbjct: 678 KRLAEQREQ---------------ERREQERREQERREQERRE-QERREQERQLAEQERR 721
Query: 831 KSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEE 888
+ + + + ER+K R + E EE ++E + + ++E++ + +E
Sbjct: 722 REQERLQAERELQEREKA-LRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 34.3 bits (77), Expect = 0.70
Identities = 15/45 (33%), Positives = 27/45 (60%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERER 350
++ +Q ++ R +ER + RR +ER Q ++ E+ RRE+ER
Sbjct: 682 EQREQERREQERREQERREQERREQERREQERQLAEQERRREQER 726
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 69.3 bits (168), Expect = 2e-11
Identities = 76/340 (22%), Positives = 152/340 (44%), Gaps = 67/340 (19%)
Query: 605 RKEADGEQDEEEKDDGEAKEIST--PTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQL 662
+++ + + EE+K D ++EIS TH KL+ + K R+E+E + + +
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTH-KKLEEEKGKKEKERQEIEKERRERERERERE 319
Query: 663 IARLTKQLKVEEQKEEQKELEKS-EKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRY 721
R ++ + E ++E +KE E+ E+E D D DR E D+ + +R+R + +R+R
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERDR-DRDRERDRDRDRER----- 373
Query: 722 ILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRD 781
S + S D E +E E E E
Sbjct: 374 ----------------SSDRNKDRSRSREKSRDRERERERERERERERERERERER---- 413
Query: 782 FGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKED 841
E+E ++E++++ +KD+++D++E+ +D + K +R+ ++K+
Sbjct: 414 -------------EREREREREREREKDKKRDREEDEEDAYERRKLERKL----REKEAA 456
Query: 842 RDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEA-------EDEEDDRDEEEMTK-- 892
ER K + ++ K + +E ++E A+EA ED +DDRD+ + +
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGS 516
Query: 893 ------RDDKRDINRYCKERPSKDKEKEKTQMITINRDLL 926
RD ++++ E +D+++EK ++ I + LL
Sbjct: 517 ALQKRLRDREKEM-----EADERDRKREKEELEEIRQRLL 551
Score = 68.2 bits (165), Expect = 4e-11
Identities = 70/298 (23%), Positives = 140/298 (46%), Gaps = 33/298 (11%)
Query: 646 KELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRK---SEDDKE 702
KE ES + + L I +KV+ + + Q + K++K+ + R + DD+E
Sbjct: 135 KEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEE 194
Query: 703 --EEERKRQEEIERQRRE---RRYI----LPDEPAIIVHPNWAAKSGKFDC-SIMSLSVL 752
+EE KR++++ + E R Y P + + HP K K D ++ L
Sbjct: 195 ALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDS-HPRKKKKEKKEDIFRRFPVAPL 253
Query: 753 LDYRLEDNKE-HSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDER 811
+ Y L ++ ++ E+ E +++ R+ + + L E++ KKEK+++ + ER
Sbjct: 254 IPYPLITKEDINAIEME---EDKRDLISREIS-KFRDTHKKLEEEKGKKEKERQEIEKER 309
Query: 812 KDKKEERDDETDEPKPKRRKSGDDKDKKE-----------DRDERKKEDKRKDDSKD--- 857
++++ ER+ E + + +R + + + +KE DRD K+ D+ +D +D
Sbjct: 310 RERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369
Query: 858 DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
D E D N+D E + E +R+ E +R+ +R+ R + +++E+EK
Sbjct: 370 DRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREK 427
Score = 63.5 bits (153), Expect = 1e-09
Identities = 61/312 (19%), Positives = 142/312 (45%), Gaps = 21/312 (6%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDE-EEKDDGEAKEISTPTHWSKLDPKTMKV 641
R E E +++ EK + +E D ++D +E+D +E D +
Sbjct: 322 RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR-------DRDRERS 374
Query: 642 NDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKS-EKEEDEDDDRKSEDD 700
+D K+ S+ + + ++ + E ++E ++E E+ E+E + + D+K + +
Sbjct: 375 SDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDRE 434
Query: 701 KEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDN 760
++EE+ + ++ER+ RE+ + NW + K + + R +
Sbjct: 435 EDEEDAYERRKLERKLREKEAAYQERLK-----NWEIRERKKTREYEKEAEREEERRREM 489
Query: 761 KEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDD 820
+ + + F E +++ RD S L ++ ++++K+ + DER D+K E+++
Sbjct: 490 AKEAKRLKEFLEDYDD--DRDDPKYYRGSAL----QKRLRDREKEMEADER-DRKREKEE 542
Query: 821 ETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAED 880
+ + + D D + R E++ E +R+ K + E+EE+ + + + EE +
Sbjct: 543 LEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPME 602
Query: 881 EEDDRDEEEMTK 892
EE++ +++ K
Sbjct: 603 EEEEPEQKPCLK 614
Score = 62.0 bits (149), Expect = 3e-09
Identities = 53/278 (19%), Positives = 136/278 (48%), Gaps = 13/278 (4%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
E+E ++E++++ +K++ ++++ ERD + D + K R D+++ DRD + D+ KD
Sbjct: 324 EREREREREREREKEKERERERERDRDRD--RTKERDRDRDRERDRDRDRERSSDRNKDR 381
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
S+ +++ + + E + E E + E +R+ E +R+ +R+ + K+R ++ E++
Sbjct: 382 SRSREKSRDRERERERE-REREREREREREREREREREREREREREK-DKKRDREEDEED 439
Query: 915 KTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVV-LRES 973
+ + R L + + + + + + Y + +++ + L+E
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE- 498
Query: 974 CFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTP--TVKQESKDVEENVGLIVYNGAM 1031
+ + D +D+ + +LQ+ + + K+E +++EE ++ G
Sbjct: 499 --FLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEG-H 555
Query: 1032 VDVGSLLQKLEKSEKVR--AEVEQKLQLLEEKTDEDEK 1067
D + LQ++E+ + R +++Q+ + EE+ ++ EK
Sbjct: 556 PDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEK 593
Score = 52.8 bits (125), Expect = 2e-06
Identities = 27/58 (46%), Positives = 34/58 (58%)
Query: 300 RFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R S RN + + DR RERERER R RER +R+R RER RERER + ++
Sbjct: 373 RSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKK 430
Score = 52.4 bits (124), Expect = 2e-06
Identities = 54/234 (23%), Positives = 108/234 (46%), Gaps = 50/234 (21%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKE--DKRK 852
EK +E++++ +++ ++++ ER+ E + + + R+ +KDKK DR+E +++ ++RK
Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445
Query: 853 DDSK------------DDDETEEDNNQDEYDPMEAEEAEDEEDDRDE---------EEMT 891
+ K + E E EY+ +EAE EE+ R E E +
Sbjct: 446 LERKLREKEAAYQERLKNWEIRERKKTREYE----KEAEREEERRREMAKEAKRLKEFLE 501
Query: 892 KRDDKRDINRYCK----ERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEE 947
DD RD +Y + ++ +D+EKE M RD +++LEE
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKE---MEADERDRKRE-------------KEELEE 545
Query: 948 I---LYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQED 998
I L G A+++++ + R ++ ++ ++EE +E E +E+
Sbjct: 546 IRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREE 599
Score = 51.6 bits (122), Expect = 4e-06
Identities = 26/57 (45%), Positives = 36/57 (63%)
Query: 300 RFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R R+ ++ +R+ +R RERERER R RER +R+R RER RERE+ +R R
Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDR 433
Score = 48.5 bits (114), Expect = 4e-05
Identities = 23/51 (45%), Positives = 33/51 (64%)
Query: 299 SRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERE 349
SR R+ ++ R+ +R RERERER R RER +R+R RE+ +R+RE
Sbjct: 384 SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDRE 434
Score = 48.1 bits (113), Expect = 5e-05
Identities = 24/53 (45%), Positives = 30/53 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R D+ +R R + R+RER R RER +R+R RER RERER R R
Sbjct: 371 RERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERER 423
Score = 47.8 bits (112), Expect = 6e-05
Identities = 23/44 (52%), Positives = 30/44 (68%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
+R DR R+R+R+R RS +R+ R RSRE+S RERER R R
Sbjct: 358 DRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER 401
Score = 47.4 bits (111), Expect = 8e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
D+ R DR+++R R R +SR+R +R+R RER RERER R R
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERER 415
Score = 46.6 bits (109), Expect = 1e-04
Identities = 24/48 (50%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
Query: 310 QVPNRKDDRSRERERER-RRSRERSPQRKRSRERSPRRERERSPRRVR 356
++ + +R RERERER RR RER +R+R RE+ RERER R R
Sbjct: 304 EIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Score = 46.6 bits (109), Expect = 1e-04
Identities = 23/53 (43%), Positives = 33/53 (62%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R D+ +R+ DR R+RER R+++RS R++SR+R RERER R R
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER 405
Score = 45.1 bits (105), Expect = 4e-04
Identities = 23/53 (43%), Positives = 33/53 (62%), Gaps = 2/53 (3%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R +R + ++ R RERERER R RE+ +R+R RER R+R+R+ R R
Sbjct: 309 RRERERERERERERREREREREREREREKEKERERERERD--RDRDRTKERDR 359
Score = 45.1 bits (105), Expect = 4e-04
Identities = 22/51 (43%), Positives = 32/51 (62%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
+R ++ R+ +R RE+E+ER R RER R R++ER R+RER R R
Sbjct: 321 ERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDR 371
Score = 44.7 bits (104), Expect = 5e-04
Identities = 21/51 (41%), Positives = 32/51 (62%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
+R + R+ +R RERERER + +ER +R+R R+R +ER+R R R
Sbjct: 315 ERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 365
Score = 44.3 bits (103), Expect = 7e-04
Identities = 22/48 (45%), Positives = 27/48 (56%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
D+ R DR RER +R + R RS ++ R RER RERER R R
Sbjct: 360 DRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER 407
Score = 43.9 bits (102), Expect = 9e-04
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 259 PLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDR 318
P+ P PL+ + A ++ R + + ++ D + + ++ +
Sbjct: 249 PVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKE 308
Query: 319 SRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
RERERER R RER R+R RER RERE+ R R
Sbjct: 309 RRERERERERERER---REREREREREREREKEKERER 343
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/57 (42%), Positives = 29/57 (50%)
Query: 300 RFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R R+ D+ +R DR R +R + RSR R R R RER RERER R R
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 409
Score = 42.4 bits (98), Expect = 0.003
Identities = 20/48 (41%), Positives = 29/48 (60%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPR 361
R+ +R RERERER R RER +R+R +++ RE + RR + R
Sbjct: 401 REREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/51 (41%), Positives = 29/51 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R ++ R+ DR R+R +ER R R+R R R RERS R ++RS R
Sbjct: 335 REKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Score = 41.2 bits (95), Expect = 0.006
Identities = 20/51 (39%), Positives = 30/51 (58%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
+R + + +R RERERER R +E+ +R+R R+R R +ER R R
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDR 363
Score = 41.2 bits (95), Expect = 0.006
Identities = 19/43 (44%), Positives = 27/43 (62%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R+ +R +E+ERER R R+R R + R+R RER+R R R
Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRER 373
Score = 40.8 bits (94), Expect = 0.007
Identities = 19/58 (32%), Positives = 30/58 (51%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSL 371
R+ +R RERERER R RE+ +R R + ER + R++R Y + + +
Sbjct: 409 REREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI 466
Score = 40.0 bits (92), Expect = 0.013
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Query: 784 VRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKED-- 841
+R Y S L+ P +E KK KK++++D P P K + + E+
Sbjct: 215 IREYSSELNAPSQESDSHPRKK-KKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDK 273
Query: 842 RDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINR 901
RD +E + D+ E E+ + E +E E E E + E E +R+ +R+ R
Sbjct: 274 RDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERER 333
Query: 902 YCKERPSKDKEKEKTQMITINRD 924
ER K+KE+E+ + +RD
Sbjct: 334 ---ER-EKEKERERERERDRDRD 352
Score = 39.7 bits (91), Expect = 0.017
Identities = 20/56 (35%), Positives = 31/56 (55%)
Query: 299 SRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
SR R ++ R+ +R RERERER R RER +R++ ++R + E + R
Sbjct: 388 SRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Score = 39.7 bits (91), Expect = 0.017
Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 22/163 (13%)
Query: 599 EKLQGERKEADGEQD---EEEKDDGEAKEISTPTHWSKLDPK-------TMKVNDLRKEL 648
+K + KEA+ E++ E K+ KE + DPK ++ D KE+
Sbjct: 470 KKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEM 529
Query: 649 ESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSE-----------KEEDEDDDRKS 697
E+ K K +L + ++L E + EL++ E K+E E ++ +
Sbjct: 530 EADERDRKREKEEL-EEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEE 588
Query: 698 EDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSG 740
E ++EE+R+ E E + ++ + P I P+ ++ SG
Sbjct: 589 EKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASG 631
Score = 38.9 bits (89), Expect = 0.028
Identities = 21/51 (41%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R ++ ++ +R RER+R+R R++ER R R RER R+RERS R
Sbjct: 329 REREREREKEKERERERERDRDRDRTKER--DRDRDRERDRDRDRERSSDR 377
Score = 38.1 bits (87), Expect = 0.048
Identities = 17/53 (32%), Positives = 30/53 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R ++ R+ +R R+R+R+R + R+R R+R R+R R +R+ R R
Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSR 383
Score = 31.6 bits (70), Expect = 4.5
Identities = 15/48 (31%), Positives = 23/48 (47%)
Query: 310 QVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
++ +D + E + ++ +ER K RER RERER R R
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 69.3 bits (168), Expect = 2e-11
Identities = 34/123 (27%), Positives = 71/123 (57%), Gaps = 10/123 (8%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
E E+ +E ++ +++E++ K++E+ E + K K++K+ + + +KE +E KK +++
Sbjct: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
K+++E EE E EE E+E+++ ++EE +R K+ R +E K K +
Sbjct: 69 KKEEEEREE----------EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Query: 915 KTQ 917
KT+
Sbjct: 119 KTK 121
Score = 67.0 bits (162), Expect = 1e-10
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 8/127 (6%)
Query: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRAL 653
K++ +K + E E E +EEE+ +G+ KE K K K + RKE E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 654 SSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIE 713
K R K+ K EE++EE++E E+ EKEE+E ++ + K++ RK +EE +
Sbjct: 61 KRK--------RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Query: 714 RQRRERR 720
+++R R+
Sbjct: 113 KKKRRRK 119
Score = 65.5 bits (158), Expect = 3e-10
Identities = 33/112 (29%), Positives = 65/112 (58%), Gaps = 3/112 (2%)
Query: 807 KKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDR---DERKKEDKRKDDSKDDDETEE 863
KK ++K K+ E +ET+E + + K G K+K++++ E+KK+ K + K+ +E E+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 864 DNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
+ E EE E+EE++ +EE+ + ++ + K+R K++E+EK
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Score = 65.1 bits (157), Expect = 4e-10
Identities = 30/116 (25%), Positives = 69/116 (59%), Gaps = 2/116 (1%)
Query: 800 KEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDD 859
K+K KK K+ E ++ EE ++E ++ ++ K + + +KE + + K+ +KRK+ +++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 860 ETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
+ + + + + EE E+EE++++EEE K + +R + + R +++EK+K
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEE--KEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 30.8 bits (68), Expect = 7.7
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 26/78 (33%)
Query: 846 KKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKE 905
KK+ K+K ++++ +ETEE EE E++E R E KR +KR
Sbjct: 1 KKKKKKKKETEETEETEE-----------TEEEEEKEGKRKE----KRKEKR-------- 37
Query: 906 RPSKDKEKEKTQMITINR 923
K+KEK+K T R
Sbjct: 38 ---KEKEKKKKTKETEKR 52
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 68.9 bits (167), Expect = 3e-11
Identities = 114/564 (20%), Positives = 234/564 (41%), Gaps = 104/564 (18%)
Query: 551 HRPEETHKG---------RTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKL 601
H PE+ K R + A V+T+ + C T + ++ Y Q V++L
Sbjct: 93 HSPEDEQKASHQHQEALRRELEAQVQTIRILT-----CQKTELQ---MALYYSQHAVKQL 144
Query: 602 QGERKEADGEQDEEEKDDGEAKEI--STPTHWSKLDPKTMKVNDLRKELESRALSSKGLK 659
+GE ++ + K GE ++ + T K D + +L KE ++ +L
Sbjct: 145 EGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD---RYIEELTKERDALSLE----- 196
Query: 660 SQLIARLTKQLKVEEQKEEQKEL-EKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRE 718
+ R T + EE KE+ +L EK + E E + E + +E++R+
Sbjct: 197 ---LYRNT--ITDEELKEKNAKLQEKLQLVESE----------KSEIQLNVKELKRKLER 241
Query: 719 RRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEML 778
+ +LP + A++ + S+S L ++E+N EL+N +
Sbjct: 242 AKLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEEN-----------ELWNRLN 283
Query: 779 QRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDK 838
Q+ +++K ++ K ER++K +E++++ E + K R+ + +
Sbjct: 284 QQ----------------QEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWE 327
Query: 839 KEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRD 898
KE++ R++E E EE + E E E+ ++E+ R EEE + +KR
Sbjct: 328 KEEKMRRQEEMMW--------EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 379
Query: 899 INRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSR 958
+ K ++K +E+ + I +++ + G + EE ++ +
Sbjct: 380 -EQEAKMWRQEEKIREQEEKIREQEEMMQE----QEEKMG-----EQEEKMWEQEEEMQE 429
Query: 959 AQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDV 1018
+ K + +RE +K+ + + EE QE+ +G + +QE+K
Sbjct: 430 QEEKMRRQEEKIREQ--EKKIREQEEKIREQEEMMQEQEEKMGEQ---EGKMCEQEAKMQ 484
Query: 1019 EENVGLIVYNGAMVDVGSLL----QKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLEN 1074
E+ + + + + +K+ + E++ E E+K+ EEK E E+ + E
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544
Query: 1075 SNKSLSGELREVKKDLSQLQENLK 1098
+ ++RE + L Q +E ++
Sbjct: 545 KMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 67.4 bits (163), Expect = 7e-11
Identities = 68/337 (20%), Positives = 157/337 (46%), Gaps = 54/337 (16%)
Query: 586 WETLSRGYKQQL---VEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
W L++ ++++ EK+Q ER+E EQ+E+ ++ E W K + K +
Sbjct: 279 WNRLNQQQEEKMWRQEEKIQ-EREEKIQEQEEKIREQEEKMRRQEEMMWEK-EEKMRRQE 336
Query: 643 DLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE 702
++ E E + +L ++ +Q K+ EQ+E+++E EK ++E + +E
Sbjct: 337 EMMWEKEEKI-------RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 703 EEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKE 762
E+ R+++E+I RE+ ++ ++ + ++ + +E
Sbjct: 390 EKIREQEEKI----REQEEMMQEQ---------------------------EEKMGEQEE 418
Query: 763 HSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDET 822
+E EM +++ +R + + EK+ +++++K +++E ++EE+ E
Sbjct: 419 KMWEQE------EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Query: 823 DEPKPKRRKSGDDKDKKEDRDE---RKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEE-- 877
+ ++ ++++K R E R++E K ++ + E EE + E E EE
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 532
Query: 878 AEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
E EE +++EE +R +++ + + R ++K +E
Sbjct: 533 CEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 44.3 bits (103), Expect = 7e-04
Identities = 69/360 (19%), Positives = 144/360 (40%), Gaps = 42/360 (11%)
Query: 804 KKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEE 863
K++++ + + KE+ D + P + D KK+ + E + + E
Sbjct: 41 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPE----TTTSGGCHSPE 96
Query: 864 DNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINR 923
D + + EA E E + +T + + + Y + K E E R
Sbjct: 97 DEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEA-------R 149
Query: 924 DLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQ--VKKLLNKVVLRESCFYRKLTD 981
DL+ + H + +LE+ L + +A +++L + R++ +
Sbjct: 150 DLI------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE---RDALSLELYRN 200
Query: 982 TSKDEENHEESESLQE--DMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQ 1039
T DEE E++ LQE ++ + VK+ + +E L+ + L +
Sbjct: 201 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 260
Query: 1040 KLEK-SEKVRAEV-------------EQKLQLLEEKTDEDEKTILNLENSNKSLSGELRE 1085
+L+ S K++A+V E+K+ EEK E E+ I E + ++R
Sbjct: 261 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 1086 VKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
++ + + +E ++ E M + E + IR L M E + +++ + E++ + +E
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEK----IRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Score = 40.0 bits (92), Expect = 0.013
Identities = 66/363 (18%), Positives = 140/363 (38%), Gaps = 75/363 (20%)
Query: 798 DKKEKDKKSKKDERKDKKEERDDETD------EPKPKRRKSGDDKDKKEDRDERKKEDKR 851
D++ K+K +K E+ E E + K +R K + + + + ++ +
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 263
Query: 852 KDDSKDDDETEED------NNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKE 905
+K + EE+ N Q E EE E +++ +E+ K ++ + R +E
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEE 323
Query: 906 RPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLL 965
+ +EK + Q EE+++ ++++L
Sbjct: 324 MMWEKEEKMRRQ----------------------------EEMMWE-----KEEKIRELE 350
Query: 966 NKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLI 1025
K+ +E R+ + ++EE E E QE +QE K E+
Sbjct: 351 EKMHEQEKI--REQEEKRQEEEKIREQEKRQEQ--------EAKMWRQEEKIREQE---- 396
Query: 1026 VYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELRE 1085
+K+ + E++ E E+K+ EEK E E+ + E + ++RE
Sbjct: 397 -------------EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443
Query: 1086 VKKDLSQLQENLKISENMNLQFENQMNKTIRNL---STVMDEIHTVLKKDNVKNEDKDQK 1142
+K + + +E ++ E M + E +M + + M E +++ K ++++K
Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK 503
Query: 1143 SKE 1145
+E
Sbjct: 504 IRE 506
Score = 34.7 bits (78), Expect = 0.54
Identities = 35/161 (21%), Positives = 72/161 (44%), Gaps = 27/161 (16%)
Query: 599 EKLQGERKEADGEQDEEEKDDGEA---KEISTPTHWSKLDPKTMKVND---LRKELESRA 652
E+ GE++E EQ+EE ++ E +E K+ + K+ + + +E E +
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 653 LSSKGLKSQLIARLTKQ---------------LKVEEQKE---EQKELEKSEKE---EDE 691
+G + A++ +Q K+ EQ+E EQ+E+ + ++E E E
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Query: 692 DDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVH 732
+ + E+ +E+E K + + E+ R + + E + H
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 68.9 bits (167), Expect = 3e-11
Identities = 125/597 (20%), Positives = 247/597 (41%), Gaps = 96/597 (16%)
Query: 575 DVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEE--KDDGEAKEISTPTHWS 632
++ H L +R E E Q +K+Q ++ + + DEEE + + ++++
Sbjct: 922 EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIK 981
Query: 633 KLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEK-SEKEEDE 691
K++ + + L ++ S+ + K L IA + QL EE+K K L K K+E
Sbjct: 982 KMEEEIL----LLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEK--AKNLAKIRNKQEVM 1035
Query: 692 DDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSV 751
D + KEE+ R+ E+ +R+ L D+ A + I L +
Sbjct: 1036 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA------------ELQAQIDELKL 1083
Query: 752 LLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSL-LSLPEKEDKKEKDKKSKKDE 810
L KE + +L A +E L ++ +++ + L + E ++ E +K S+
Sbjct: 1084 QL-----AKKEEELQGAL-ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA 1137
Query: 811 RKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDE-RKKEDKRKDDSKDDDETEEDNNQDE 869
K K+ D ++E + + + D D + E R K ++ + K E E N++ +
Sbjct: 1138 EKQKR----DLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193
Query: 870 YDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDL---- 925
M A E+ ++ E KR + EK K + T N++L
Sbjct: 1194 IQDMRQRHATALEELSEQLEQAKRF-------------KANLEKNKQGLETDNKELACEV 1240
Query: 926 -LMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSK 984
++ V + H L+ ++E LH ++ +L ++ + S +L + S
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQVQE------LHAKVSEGDRLRVELAEKASKLQNELDNVST 1294
Query: 985 DEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKS 1044
E E+ G + +++ + +D +E + QKL S
Sbjct: 1295 LLEEAEKK--------GIKFAKDAASLESQLQDTQELL-----------QEETRQKLNLS 1335
Query: 1045 EKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKK----DLSQLQ------ 1094
++R ++E++ L+E+ +E+E+ NLE +L +L + KK DL ++
Sbjct: 1336 SRIR-QLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAK 1394
Query: 1095 -ENLKISENMNLQFE------NQMNKTIRNLSTVMDEIHTVL--KKDNVKNEDKDQK 1142
+ LK +E ++ + E +++ KT L +D++ L ++ N +K QK
Sbjct: 1395 KKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQK 1451
Score = 64.7 bits (156), Expect = 5e-10
Identities = 126/593 (21%), Positives = 245/593 (41%), Gaps = 79/593 (13%)
Query: 595 QQLVEKLQGERKEADGEQDE--EEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRA 652
QQ+ + + +RK+ D + E + +G+ + SKL + V+ L +E E +
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 653 LS----SKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKR 708
+ + L+SQL + T++L Q+E +++L S + ++++ S +++EEE +
Sbjct: 1304 IKFAKDAASLESQL--QDTQELL---QEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEA 1358
Query: 709 QEEIER-------QRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNK 761
++ +E+ Q + + + D+ I A K D +S L + L +K
Sbjct: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALS-QRLEEKALAYDK 1417
Query: 762 EHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDK---KEKDKKSKKDERKDKKEER 818
+ L EL + + D ++ +L +K D+ +EK ++ E +D+ E
Sbjct: 1418 LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAE 1477
Query: 819 DDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKD-----DSKDD-----DETEED---- 864
E + ++ ++ + ++ ER+ + R D SKDD E E+
Sbjct: 1478 AREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL 1537
Query: 865 NNQDEYDPMEAEEAEDE----EDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMIT 920
Q E + EE EDE ED + E+ + K R + R +++EK++ +
Sbjct: 1538 EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ 1597
Query: 921 INRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLT 980
+ Q +K +E L L + A K ++V+ + RKL
Sbjct: 1598 VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAA--NKARDEVIKQ----LRKLQ 1651
Query: 981 DTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQK 1040
KD + E D + +SK+ E+ + ++ L ++
Sbjct: 1652 AQMKDYQRELEEARASRD-----------EIFAQSKESEKKL-----KSLEAEILQLQEE 1695
Query: 1041 LEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKIS 1100
L SE+ R EQ + DE I N + +L E R ++ ++QL+E L+
Sbjct: 1696 LASSERARRHAEQ-------ERDELADEITNSASGKSALLDEKRRLEARIAQLEEELE-E 1747
Query: 1101 ENMNLQFEN-QMNKTIRNLSTVMDEI----HTVLKKDN----VKNEDKDQKSK 1144
E N++ N + KT + T+ E+ K DN ++ ++K+ K+K
Sbjct: 1748 EQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800
Score = 47.4 bits (111), Expect = 8e-05
Identities = 53/245 (21%), Positives = 112/245 (45%), Gaps = 31/245 (12%)
Query: 873 MEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKE--KEKTQMITINRDLLMAFV 930
++ E+E +DEE + ++ + + +E K ++ +EK + + F
Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904
Query: 931 YFDQSHCGYLLEK-DLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKD-EEN 988
++ +K +LEEIL+ L SR + ++ N+++ E +K+ +D EE
Sbjct: 905 EAEEMRARLAAKKQELEEILHDLE---SRVEEEEERNQILQNEK---KKMQAHIQDLEEQ 958
Query: 989 HEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLI------------VYNGAMVDVGS 1036
+E E ++ +L L T + + K +EE + L+ + + + S
Sbjct: 959 LDEEEGARQ-----KLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013
Query: 1037 LLQKLEKSEKVRAEVEQKLQL----LEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQ 1092
L + E+ K A++ K ++ LEE+ ++EKT LE + + L GE +++ +++
Sbjct: 1014 QLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE 1073
Query: 1093 LQENL 1097
LQ +
Sbjct: 1074 LQAQI 1078
Score = 46.2 bits (108), Expect = 2e-04
Identities = 90/470 (19%), Positives = 188/470 (40%), Gaps = 72/470 (15%)
Query: 668 KQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEP 727
K L ++EE+ + + E + ++ K E + EE ERK Q+ +E +
Sbjct: 842 KPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEK------------ 889
Query: 728 AIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIY 787
N A+ + + + + + + RL K+ E I
Sbjct: 890 ------NILAEQLQAETELFAEAEEMRARLAAKKQELEE-------------------IL 924
Query: 788 KSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKK 847
L S E+E+++ + +++K + + ++ +++ DE + R+K +K E + ++ +
Sbjct: 925 HDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKME 984
Query: 848 ED-KRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDD------RDEEEMTKRDDKRDIN 900
E+ +D E+ +D ++ AE+EE R+++E+ D + +
Sbjct: 985 EEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLK 1044
Query: 901 RYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLG------L 954
+ K R +K K K T + +A + L K EE+ L L
Sbjct: 1045 KEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETL 1104
Query: 955 HLSRA--QVKKLLNKVV-LRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTV 1011
H + A V++L ++ L+E K + +++ + SE L+ L T
Sbjct: 1105 HKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAA 1164
Query: 1012 KQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEK--------VRAEVEQKLQLLEEKTD 1063
+QE + E +V L + LE+ K +R L+ L E+ +
Sbjct: 1165 QQELRTKREQ-----------EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE 1213
Query: 1064 EDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNK 1113
+ ++ NLE + + L + +E+ ++ LQ+ SE+ + + Q+ +
Sbjct: 1214 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQE 1263
Score = 42.4 bits (98), Expect = 0.003
Identities = 68/348 (19%), Positives = 141/348 (40%), Gaps = 59/348 (16%)
Query: 834 DDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQ--DEYDPMEAEEAEDEEDDRDEEEMT 891
+++ + +D + K ++K+ + +E E + Q +E + + + + E + EEM
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 892 KR--DDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEIL 949
R K+++ + S+ +E+E+ I N M Q+H L E+ EE
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKM------QAHIQDLEEQLDEEEG 964
Query: 950 YTLGLHLSR----AQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLL 1005
L L + A++KK+ +++L E + S+ ++E L +
Sbjct: 965 ARQKLQLEKVTAEAKIKKMEEEILLLED----------------QNSKFIKEKKLMEDRI 1008
Query: 1006 LPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDED 1065
+ E ++ +N+ I N V + L ++L+K EK R E+E+ + L+ +T +
Sbjct: 1009 AECSSQLAEEEEKAKNLAKI-RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDL 1067
Query: 1066 EKTI-----------LNLENSNKSLSGEL-----------------REVKKDLSQLQENL 1097
+ I L L + L G L RE++ +++LQE+
Sbjct: 1068 QDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1127
Query: 1098 KISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
+ + + E Q L + E+ L + E + ++ +E
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQE 1175
Score = 40.0 bits (92), Expect = 0.013
Identities = 72/325 (22%), Positives = 132/325 (40%), Gaps = 48/325 (14%)
Query: 600 KLQGERK-EADGEQDEEEKD---------DGEAKEISTPTHWSKLDPKTMKVNDLRKELE 649
K Q ER + EQ+EE+K + E ++ + K M+++ K+LE
Sbjct: 1573 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEID--LKDLE 1630
Query: 650 SRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK-----EEE 704
++ ++ + ++I +L K + K+ Q+ELE++ DE + E +K E E
Sbjct: 1631 AQIEAANKARDEVIKQLRKLQA--QMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688
Query: 705 ERKRQEEIERQRRERRYILP--DEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKE 762
+ QEE+ R RR+ DE A + + + KS D L + E+ +E
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLD-EKRRLEARIAQLEEELEE 1747
Query: 763 HSFEVSLFAELFNEM-LQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDD- 820
+ L + F + LQ D + S +K D + + + E K K +E +
Sbjct: 1748 EQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGA 1807
Query: 821 -----------------ETDEPKPKRRKSGDDKDKKEDRDERKK-------EDKRKDDSK 856
+ +E + K +K R E+K ED+R+ +
Sbjct: 1808 VKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQ 1867
Query: 857 DDDETEEDNNQDEYDPMEAEEAEDE 881
++ E+ N + + + EEAE+E
Sbjct: 1868 YKEQMEKANARMKQLKRQLEEAEEE 1892
Score = 32.7 bits (73), Expect = 2.0
Identities = 53/283 (18%), Positives = 108/283 (38%), Gaps = 43/283 (15%)
Query: 595 QQLVEKLQGERKEADGEQDEEEKD--DGEAKEISTPTHWSKLDPKTMKVNDLRKELESRA 652
Q+ +E+ + R E + E EK EA+ + + + R EL
Sbjct: 1658 QRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEI 1717
Query: 653 LSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKS-------------ED 699
+S KS L+ + Q EE+ E E+S E D RK+ E
Sbjct: 1718 TNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAER 1777
Query: 700 DKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLED 759
++ ++++ERQ +E + L + + KF +I +L + +LE+
Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGAV--------KSKFKATISALEAKIG-QLEE 1828
Query: 760 NKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERD 819
E + A N++++R +KK K+ + ++ + ++
Sbjct: 1829 QLEQEAKERAAA---NKLVRRT----------------EKKLKEIFMQVEDERRHADQYK 1869
Query: 820 DETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETE 862
++ ++ + ++ ++ E+ R +RK + DD TE
Sbjct: 1870 EQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATE 1912
Score = 32.3 bits (72), Expect = 2.7
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 1043 KSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISEN 1102
++E++RA + K Q LEE + E + E N+ L E ++++ + L+E L E
Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG 964
Query: 1103 MNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKEN 1146
+ Q+ K E +L +D K++K E+
Sbjct: 965 ARQKL--QLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMED 1006
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 67.8 bits (164), Expect = 6e-11
Identities = 58/235 (24%), Positives = 113/235 (48%), Gaps = 21/235 (8%)
Query: 646 KELESRALSSKGLKSQLIA--RLTKQL--KVEEQKEEQKELEKS--EKEEDEDDDRKSED 699
K + SRA + Q+++ ++K + E+K+E++E EK E+E++ +R ++
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKE 62
Query: 700 DKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLED 759
K+ ++R+R +E ER+R+ER + K + R +
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKR-------------ERKQR 109
Query: 760 NKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDK-KSKKDERKDKKEER 818
+ + E E QR R K KE K+EK++ K ++ +K KKEER
Sbjct: 110 GRRERKKKKERKERERENKQRRERKR-KKRRKKKRRKERKREKERGKRERKRKKRKKEER 168
Query: 819 DDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPM 873
+ + + + +R+K + K+++E + ERKKE ++K + K D +T+ + + P+
Sbjct: 169 EKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPL 223
Score = 60.5 bits (145), Expect = 9e-09
Identities = 34/111 (30%), Positives = 61/111 (54%), Gaps = 7/111 (6%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDE------TDEPKPKRRKSGDDKDKKEDRDERKKE 848
+KE KK + K+ + ERK KKE ++ E + + KRRK K++K +++ K+E
Sbjct: 98 KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157
Query: 849 DKRKDDSKDDDETEEDNNQDE-YDPMEAEEAEDEEDDRDEEEMTKRDDKRD 898
KRK K++ E + + N+ E E +E + + +R +E K++ K+D
Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Score = 58.9 bits (141), Expect = 3e-08
Identities = 40/134 (29%), Positives = 71/134 (52%), Gaps = 14/134 (10%)
Query: 795 EKEDKKEKDKKSKK--------DERKDKKEERDDETDEPKPK-RRKSGDDKDKKE----D 841
EKE K+E+ KK KK ER+ K++ER+ + E + K RRK +K K+E
Sbjct: 51 EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
Query: 842 RDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINR 901
R ERKK+ +RK+ +++ + E + +E + E +R + E ++ K++
Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK-REKERGKRERKRKKRKKEERE 169
Query: 902 YCKERPSKDKEKEK 915
+ER K+++KE+
Sbjct: 170 KKRERNRKERKKER 183
Score = 57.4 bits (137), Expect = 8e-08
Identities = 28/122 (22%), Positives = 70/122 (57%), Gaps = 2/122 (1%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERD-DETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKD 853
E E KKE+ ++ K+ ++K+ +R+ + ++ K K+R+ G ++++K E++++++R+
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 854 DSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEK 913
+ + + ++ + + E ++ + E +R+ E +R+ KR R K R + +EK
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKK-KKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 914 EK 915
E+
Sbjct: 152 ER 153
Score = 57.0 bits (136), Expect = 1e-07
Identities = 38/135 (28%), Positives = 73/135 (54%), Gaps = 13/135 (9%)
Query: 796 KEDKKEKDKKSKKDERKDKKEERDDETDEPKPK-RRKSGDDKDKKE----DRDERKKEDK 850
K++KK++ K+ + ER+ K++ER+ + E + K RRK +K K+E R ERKK+ +
Sbjct: 60 KKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE 119
Query: 851 RKDDSKDDDETEEDNNQDEYDPMEAEEAEDEED------DRDEEEMTKRDDKRDINRY-- 902
RK+ +++ + E + +E + E++ R + + +R+ KR+ NR
Sbjct: 120 RKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKER 179
Query: 903 CKERPSKDKEKEKTQ 917
KER K++ + K +
Sbjct: 180 KKERERKERRERKKE 194
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/123 (22%), Positives = 71/123 (57%), Gaps = 5/123 (4%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
++ ++K K+++ ++ ER++K+ + + + + ++++ ++ KK++R ER++E+K++ +
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
K ++ ++ E + E + R +EE R+ KR+ NR KER + + KE
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE---REKKRERNR--KERKKERERKE 187
Query: 915 KTQ 917
+ +
Sbjct: 188 RRE 190
Score = 55.1 bits (131), Expect = 4e-07
Identities = 30/126 (23%), Positives = 71/126 (56%), Gaps = 4/126 (3%)
Query: 795 EKEDKKEKDKK---SKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKR 851
+++ ++EK++K KK+++K KK ER E + + +R K ++ +KE R +K++ KR
Sbjct: 45 KRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKR 104
Query: 852 KDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDK 911
+ + E ++ + E + E ++ + + + ++ +++ KR+ R +ER K +
Sbjct: 105 ERKQRGRRERKKKKERKERE-RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR 163
Query: 912 EKEKTQ 917
+KE+ +
Sbjct: 164 KKEERE 169
Score = 50.8 bits (120), Expect = 7e-06
Identities = 26/122 (21%), Positives = 66/122 (54%), Gaps = 3/122 (2%)
Query: 796 KEDKKEKDKKSKKDERKDKK--EERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKD 853
++ +KE+ +K ++ +K+KK E + E K K+ + +++ K+ R+ ++K+ ++K
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
Query: 854 DSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEK 913
K+ +E ++ +E +++ +R+ +E K ++++ KER K++ K
Sbjct: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER-KKERRK 201
Query: 914 EK 915
+K
Sbjct: 202 KK 203
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/127 (21%), Positives = 71/127 (55%), Gaps = 8/127 (6%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERD------DETDEPKPKRRKSGDDKDKKEDRDERKKE 848
EK+ K+ ++K+ +K RK +K++R+ E + K ++ + ++K ++E + +++++
Sbjct: 83 EKQRKERREKERRK--RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK 140
Query: 849 DKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPS 908
KR+ + K + E + + + E E + E + ++ ++ +R ++R+ + K+
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
Query: 909 KDKEKEK 915
K KE++K
Sbjct: 201 KKKERKK 207
Score = 48.9 bits (115), Expect = 3e-05
Identities = 45/240 (18%), Positives = 106/240 (44%), Gaps = 42/240 (17%)
Query: 584 SEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVND 643
+E + +S + + + + ERK+ E+++ +++ +E K + K K +
Sbjct: 15 TELQMVSCSHISKPCTQRESERKKERREREKRKRE----REKERKRERGKKEKKKRKKRE 70
Query: 644 LRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEE 703
KE E + + + + + ++ K E++K E+K+ + E+++ ++ + ++K+
Sbjct: 71 RGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR 130
Query: 704 EERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEH 763
ERKR++ +++RR+ R + GK + R ++ +E
Sbjct: 131 RERKRKKRRKKKRRKER-------------KREKERGKRERKRKK-------RKKEEREK 170
Query: 764 SFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETD 823
E R K E+++++E+ K+ KK+ RK K+ ++D +TD
Sbjct: 171 KRE------------------RNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212
Score = 44.7 bits (104), Expect = 5e-04
Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 304 RNDRGDQVPNRKDDRS-RERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R RG + +K +R RERE ++RR R+R +RK+ R + +RE+ER R +R
Sbjct: 106 RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKR 160
Score = 43.1 bits (100), Expect = 0.002
Identities = 21/52 (40%), Positives = 34/52 (65%), Gaps = 3/52 (5%)
Query: 306 DRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
+RG + RK + ERE++R R+R+ +RK+ RER RRER++ ++ RR
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNRK---ERKKERERKERRERKKERKKERR 200
Score = 41.2 bits (95), Expect = 0.006
Identities = 19/54 (35%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
+ +RG + ++ R R +ERER+R +ER QRK RE+ R+ ++ +R R+
Sbjct: 55 KRERGKKEKKKRKKRERGKERERKR-KEREKQRKERREKERRKRKKEKKKRERK 107
Score = 40.4 bits (93), Expect = 0.010
Identities = 19/45 (42%), Positives = 30/45 (66%), Gaps = 1/45 (2%)
Query: 314 RKDDRSRERERERRRSRERSPQRK-RSRERSPRRERERSPRRVRR 357
+K+ + RER++ RR R++ +RK R RE RRER+R RR ++
Sbjct: 98 KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
Score = 40.0 bits (92), Expect = 0.013
Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSR---ERSPRRERERSPRRVRR 357
R+ +R +ER +R RER +RKR R E+ R++RER R R+
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK 78
Score = 40.0 bits (92), Expect = 0.013
Identities = 15/54 (27%), Positives = 31/54 (57%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
+ +RG + ++ +R ++R+ R + R + + K+ RER R RER ++ R+
Sbjct: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK 121
Score = 40.0 bits (92), Expect = 0.013
Identities = 18/41 (43%), Positives = 31/41 (75%), Gaps = 1/41 (2%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R++ + RER+R++RR ++R +RKR +ER +RER+R R+
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERG-KRERKRKKRK 164
Score = 39.7 bits (91), Expect = 0.017
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 11/77 (14%)
Query: 286 VSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRER---ERERRRSRERSPQRKRSR-- 340
+S+P R + R R +R + R+ +R RER E+++R+ RER +R+R R
Sbjct: 25 ISKPCTQRESE---RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKE 81
Query: 341 ---ERSPRRERERSPRR 354
+R RRE+ER R+
Sbjct: 82 REKQRKERREKERRKRK 98
Score = 39.7 bits (91), Expect = 0.017
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 314 RKDDRSRERERERRRSRERSPQRK---RSRERSPRRERERSPRRVRR 357
R++ R+RERE+ R RER + K + RER RER+R R +R
Sbjct: 40 RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Score = 39.3 bits (90), Expect = 0.022
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 314 RKDDRSRERERERRRS-RERSPQRKRSRERSPRRERERSPRRVRR 357
RK R +ER+RE+ R RER ++++ ER +RER R R+ R
Sbjct: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183
Score = 38.9 bits (89), Expect = 0.028
Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 6/50 (12%)
Query: 314 RKDDRSRERE---RERRRSRERSPQRKRSRERS---PRRERERSPRRVRR 357
R+ +R RE+E RER+R + + +R++ RER+ ++ERER RR R+
Sbjct: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Score = 37.7 bits (86), Expect = 0.063
Identities = 31/141 (21%), Positives = 65/141 (46%), Gaps = 3/141 (2%)
Query: 583 RSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVN 642
R E E R +++ E+ Q R+E +++ +E++ E K+ + K K
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERER-ENKQRRERKRKKRRKKKRRKER 147
Query: 643 DLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE 702
KE R K K + + ++ + E +KE +++ + K+E + + RK ++ K+
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
Query: 703 EEERKRQ--EEIERQRRERRY 721
+ + RQ ++ R RE +
Sbjct: 208 DRKTDRQTDSQVFRPLRESAF 228
Score = 37.4 bits (85), Expect = 0.083
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R ++ + RK R ++R +ER+R +ER KR R+R R++ ER +R R
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERG---KRERKRKKRKKEEREKKRER 174
Score = 37.0 bits (84), Expect = 0.11
Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 3/42 (7%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
NRK+ R++ERER+ RER +RK+ R + R+++R R
Sbjct: 175 NRKE---RKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
Score = 35.0 bits (79), Expect = 0.41
Identities = 14/37 (37%), Positives = 24/37 (64%)
Query: 321 ERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
+RE ER++ R +RKR RE+ +RER + ++ R+
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRK 67
Score = 35.0 bits (79), Expect = 0.41
Identities = 14/53 (26%), Positives = 31/53 (58%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R +R Q R++ R+R++E+++ + R+ +++ R+ERER ++ R
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRR 131
Score = 35.0 bits (79), Expect = 0.41
Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 304 RNDRGDQVPNRKDDRSR-ERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
R R + +K +R+R ER++ER R R +++R +ER ++ER++ + R+
Sbjct: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
Score = 30.8 bits (68), Expect = 7.7
Identities = 11/46 (23%), Positives = 27/46 (58%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERE 349
+ +R + ++ +R RER++ R +ER +++R ++R R+ +
Sbjct: 171 KRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTD 216
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 67.0 bits (162), Expect = 1e-10
Identities = 72/342 (21%), Positives = 148/342 (43%), Gaps = 42/342 (12%)
Query: 585 EWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTH-----WSKLDPKTM 639
E +TL + + + + +KE +GE+++ + D AKE+ W + K+
Sbjct: 623 EGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDS-AKELQRSVEFDREFWKENFFKSD 681
Query: 640 KVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQ-KEEQKELEKSEKEEDEDDDRKSE 698
+ DL +E +L+ L K+ K+E+ K+++ EK +E + + +
Sbjct: 682 ETEDLFLNMEHESLT-----------LEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDK 730
Query: 699 DDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLE 758
KE E+ R+E+I+ + ER I D+ + +A ++ + +E
Sbjct: 731 IKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEI----DIE 786
Query: 759 DNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKK--EKDKKSKKDERKDK-K 815
++H E E +++ ++D EK ++K EK+KK K + + +K K
Sbjct: 787 KQEKHIKESKEKPEKRSQIKEKDI------------EKMERKTFEKEKKIKHEHKSEKDK 834
Query: 816 EERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDK--RKDDSKDDDETEEDNNQDEYDPM 873
+ + D+ K K + +K E+ K +K D ++ + D D+ P
Sbjct: 835 LDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKP- 893
Query: 874 EAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
E+ + +++ M K++ + D + Y K K+KEK++
Sbjct: 894 --EKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDR 933
Score = 60.5 bits (145), Expect = 9e-09
Identities = 92/366 (25%), Positives = 156/366 (42%), Gaps = 45/366 (12%)
Query: 580 LPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTM 639
+PT + E S G + E + E + + +++EK E+KE P S++ K +
Sbjct: 754 IPTDKDSEFTSLGMSA-IEESIGLHLVEKEIDIEKQEKHIKESKE--KPEKRSQIKEKDI 810
Query: 640 KVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQK----ELEKSEKEEDEDDDR 695
+ + RK E KS+ +L V++ KE+ K EK KE ++ +
Sbjct: 811 EKME-RKTFEKEKKIKHEHKSEK-DKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNT 868
Query: 696 ---KSEDDKEEEERK--RQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLS 750
K DD+E+ K R+ + E+ +ER E ++ N + + ++ S +
Sbjct: 869 AAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKN 928
Query: 751 VLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRI-------YKSLLSLPEKE------ 797
D L D KE S + ++ +Q + I ++ LSL EK
Sbjct: 929 KEKDREL-DKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLK 987
Query: 798 --DKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKE----DRDERKKEDKR 851
D KEKDKK K +R ++++ D+ + KS DK K + +D R KE +
Sbjct: 988 TPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRL 1047
Query: 852 KDDSKDDDETEEDNNQDEYDPM-EAEEAEDEEDDRDEEEMTKRDDKRDI-NRYCKERPSK 909
+D D Q ++ M ++ E E+ + +E K+ +K + NR C E K
Sbjct: 1048 VND---------DLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIK 1098
Query: 910 DKEKEK 915
DKEK K
Sbjct: 1099 DKEKTK 1104
Score = 58.9 bits (141), Expect = 3e-08
Identities = 104/588 (17%), Positives = 223/588 (37%), Gaps = 63/588 (10%)
Query: 593 YKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPT----HWSKLDPKTMKVNDLRKEL 648
Y + K Q + + +++ + K+IST S D +T K + E
Sbjct: 384 YPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEH 443
Query: 649 ESRALSSKGLKSQLIARLTKQLKVEEQKEEQKE---------LEKSEKEEDEDDDRKSED 699
+ + + LK+Q + ++LK E++ +E L+ SEK +E + RKS
Sbjct: 444 KQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFS 503
Query: 700 DKEEEE------------------RKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGK 741
K++ ++Q +Q + + P + + P+
Sbjct: 504 PKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNT 563
Query: 742 FDCSIMSLSVLLDYRLEDNKEHSFEVSL-FAELFNEMLQRDFGVRIYKS---LLSLPEKE 797
+ S + + ++ +H + L F E N ++ + +++ L +KE
Sbjct: 564 ESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKE 623
Query: 798 DKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKD 857
K K K K ER+ +K +++ E ++ K K + S + + + D + K++
Sbjct: 624 GKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDR----EFWKENFFK 679
Query: 858 DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQ 917
DETE+ E++ + E+ E + +++ TK + +ER KE EK+
Sbjct: 680 SDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSF 739
Query: 918 MITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYR 977
+DL + I ++GLHL ++ + ++ES
Sbjct: 740 REEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKES---- 795
Query: 978 KLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSL 1037
+ E + + + + + +K E K ++ +D+
Sbjct: 796 -----KEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDK----------LDLSEC 840
Query: 1038 LQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENL 1097
+ K+++ +K+ + +K EK+ + T + ++ S E + K D + ++
Sbjct: 841 VDKIKEKDKLYSHHTEKCHKEGEKS---KNTAAIKKTDDREKSREKMDRKHDKEKPEKER 897
Query: 1098 KISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
++E+ + NK N E +KD + DK +KS++
Sbjct: 898 HLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKD--RELDKKEKSRD 943
Score = 54.3 bits (129), Expect = 7e-07
Identities = 101/477 (21%), Positives = 184/477 (38%), Gaps = 68/477 (14%)
Query: 585 EWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDL 644
E E+L+ K +L + ++ ++ + +E E +I + S + K + +
Sbjct: 691 EHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEE 750
Query: 645 R------KELESRALSSKGLKSQLIARLT-KQLKVEEQKEEQKELEKSEKEEDEDDDRKS 697
R K+ E +L ++ + L K++ +E+Q++ KE KE+ E +
Sbjct: 751 RENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKE----SKEKPEKRSQIK 806
Query: 698 EDDKEEEERKRQEEIERQRRERRY-------------ILPDEPAIIVHPNWAAKSGKFDC 744
E D E+ ERK E+ ++ + E + I + H K G+
Sbjct: 807 EKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSK 866
Query: 745 SIMSLSVLLDYRL-------EDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKE 797
+ ++ D + +KE + AE + L + S S EK
Sbjct: 867 NTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKG 926
Query: 798 DKKEKDKK-SKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDS- 855
KEKD++ KK++ +DK+ + + +++ S D +K + ++K KD+
Sbjct: 927 KNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPL 986
Query: 856 KDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
K D E+D +D++ DR +E K DK IN K + DK K K
Sbjct: 987 KTPDGKEKDK-------------KDKDIDR-YKERDKHKDKIQINSLLKLKSEADKPKPK 1032
Query: 916 TQMIT----------INRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLL 965
+ + +N DL+ S L KDLE + H + K
Sbjct: 1033 SSPASKDTRPKEKRLVNDDLMQT------SFERMLSLKDLEIEQW----HKKHKEKIKQK 1082
Query: 966 NKVVLR-ESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEEN 1021
K LR +C K+ D K + ES++ + + + T +++ KD N
Sbjct: 1083 EKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN 1139
Score = 37.7 bits (86), Expect = 0.063
Identities = 55/266 (20%), Positives = 111/266 (41%), Gaps = 20/266 (7%)
Query: 606 KEADGEQDEEEKDDGEAKEI---------STPTHWSKLDPKTMKVND--LRKELESRALS 654
++ D E+ E+E+ E+KE S + +SK + K D L K+ +SR
Sbjct: 886 RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE 945
Query: 655 SKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIER 714
S + + + K+ + + + Q E S KE+ +D+ K+ D KE++ K+ ++I+R
Sbjct: 946 SINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKD--KKDKDIDR 1003
Query: 715 QRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNK---EHSFEVSLFA 771
+ ++ + I ++ KS S D R ++ + + + S
Sbjct: 1004 YKERDKH----KDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFER 1059
Query: 772 ELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRK 831
L + L+ + + +K + EKE + ++ K + K+K + E+ + R K
Sbjct: 1060 MLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSK 1119
Query: 832 SGDDKDKKEDRDERKKEDKRKDDSKD 857
S + D + K + S D
Sbjct: 1120 SSEVTDAYTKEKQPKDAVSNRSQSVD 1145
Score = 37.0 bits (84), Expect = 0.11
Identities = 67/315 (21%), Positives = 119/315 (37%), Gaps = 71/315 (22%)
Query: 834 DDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDE-------YDPMEAEEAEDEEDDRD 886
DD + D +E + + D D ETE+D+ E P+ + E E D D
Sbjct: 285 DDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDD 344
Query: 887 EEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLE 946
+EE+ K D R I R ++R + E EKT
Sbjct: 345 DEEINKMIDDRHILRK-EQRKENEPEAEKT------------------------------ 373
Query: 947 EILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEEN---HEESESLQEDMLGNR 1003
HL Q E FY K + K + + + +ES E+ L N+
Sbjct: 374 --------HLFAKQ-----------EKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNK 414
Query: 1004 LLLPTPTVKQESKDVE-ENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKT 1062
+ + +V E+ + + + V +G G + +KL+ K + E K +EK
Sbjct: 415 KISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELK----QEKE 470
Query: 1063 DEDEKTILNLE-NSNKSLSGELREVKKDLSQLQENLKISENMNLQ-FENQMNKTIRNLST 1120
++ I NL N+ S + RE +++ ++ +L F K+ ++
Sbjct: 471 GKENTRITNLTVNTGLDCSEKTREE----GNFRKSFSPKDDTSLHLFHISTGKSPKHSCG 526
Query: 1121 VMDEIHTVLKKDNVK 1135
+ ++ T LK+++ K
Sbjct: 527 LSEKQSTPLKQEHTK 541
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 67.0 bits (162), Expect = 1e-10
Identities = 72/342 (21%), Positives = 148/342 (43%), Gaps = 42/342 (12%)
Query: 585 EWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTH-----WSKLDPKTM 639
E +TL + + + + +KE +GE+++ + D AKE+ W + K+
Sbjct: 646 EGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDS-AKELQRSVEFDREFWKENFFKSD 704
Query: 640 KVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQ-KEEQKELEKSEKEEDEDDDRKSE 698
+ DL +E +L+ L K+ K+E+ K+++ EK +E + + +
Sbjct: 705 ETEDLFLNMEHESLT-----------LEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDK 753
Query: 699 DDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLE 758
KE E+ R+E+I+ + ER I D+ + +A ++ + +E
Sbjct: 754 IKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEI----DIE 809
Query: 759 DNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKK--EKDKKSKKDERKDK-K 815
++H E E +++ ++D EK ++K EK+KK K + + +K K
Sbjct: 810 KQEKHIKESKEKPEKRSQIKEKDI------------EKMERKTFEKEKKIKHEHKSEKDK 857
Query: 816 EERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDK--RKDDSKDDDETEEDNNQDEYDPM 873
+ + D+ K K + +K E+ K +K D ++ + D D+ P
Sbjct: 858 LDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKP- 916
Query: 874 EAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
E+ + +++ M K++ + D + Y K K+KEK++
Sbjct: 917 --EKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDR 956
Score = 60.5 bits (145), Expect = 9e-09
Identities = 92/366 (25%), Positives = 156/366 (42%), Gaps = 45/366 (12%)
Query: 580 LPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTM 639
+PT + E S G + E + E + + +++EK E+KE P S++ K +
Sbjct: 777 IPTDKDSEFTSLGMSA-IEESIGLHLVEKEIDIEKQEKHIKESKE--KPEKRSQIKEKDI 833
Query: 640 KVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQK----ELEKSEKEEDEDDDR 695
+ + RK E KS+ +L V++ KE+ K EK KE ++ +
Sbjct: 834 EKME-RKTFEKEKKIKHEHKSEK-DKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNT 891
Query: 696 ---KSEDDKEEEERK--RQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLS 750
K DD+E+ K R+ + E+ +ER E ++ N + + ++ S +
Sbjct: 892 AAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKN 951
Query: 751 VLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRI-------YKSLLSLPEKE------ 797
D L D KE S + ++ +Q + I ++ LSL EK
Sbjct: 952 KEKDREL-DKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLK 1010
Query: 798 --DKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKE----DRDERKKEDKR 851
D KEKDKK K +R ++++ D+ + KS DK K + +D R KE +
Sbjct: 1011 TPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRL 1070
Query: 852 KDDSKDDDETEEDNNQDEYDPM-EAEEAEDEEDDRDEEEMTKRDDKRDI-NRYCKERPSK 909
+D D Q ++ M ++ E E+ + +E K+ +K + NR C E K
Sbjct: 1071 VND---------DLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIK 1121
Query: 910 DKEKEK 915
DKEK K
Sbjct: 1122 DKEKTK 1127
Score = 58.9 bits (141), Expect = 3e-08
Identities = 104/588 (17%), Positives = 223/588 (37%), Gaps = 63/588 (10%)
Query: 593 YKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPT----HWSKLDPKTMKVNDLRKEL 648
Y + K Q + + +++ + K+IST S D +T K + E
Sbjct: 407 YPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEH 466
Query: 649 ESRALSSKGLKSQLIARLTKQLKVEEQKEEQKE---------LEKSEKEEDEDDDRKSED 699
+ + + LK+Q + ++LK E++ +E L+ SEK +E + RKS
Sbjct: 467 KQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFS 526
Query: 700 DKEEEE------------------RKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGK 741
K++ ++Q +Q + + P + + P+
Sbjct: 527 PKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNT 586
Query: 742 FDCSIMSLSVLLDYRLEDNKEHSFEVSL-FAELFNEMLQRDFGVRIYKS---LLSLPEKE 797
+ S + + ++ +H + L F E N ++ + +++ L +KE
Sbjct: 587 ESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKE 646
Query: 798 DKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKD 857
K K K K ER+ +K +++ E ++ K K + S + + + D + K++
Sbjct: 647 GKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDR----EFWKENFFK 702
Query: 858 DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQ 917
DETE+ E++ + E+ E + +++ TK + +ER KE EK+
Sbjct: 703 SDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSF 762
Query: 918 MITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYR 977
+DL + I ++GLHL ++ + ++ES
Sbjct: 763 REEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKES---- 818
Query: 978 KLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSL 1037
+ E + + + + + +K E K ++ +D+
Sbjct: 819 -----KEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDK----------LDLSEC 863
Query: 1038 LQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENL 1097
+ K+++ +K+ + +K EK+ + T + ++ S E + K D + ++
Sbjct: 864 VDKIKEKDKLYSHHTEKCHKEGEKS---KNTAAIKKTDDREKSREKMDRKHDKEKPEKER 920
Query: 1098 KISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKE 1145
++E+ + NK N E +KD + DK +KS++
Sbjct: 921 HLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKD--RELDKKEKSRD 966
Score = 54.3 bits (129), Expect = 7e-07
Identities = 101/477 (21%), Positives = 184/477 (38%), Gaps = 68/477 (14%)
Query: 585 EWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDL 644
E E+L+ K +L + ++ ++ + +E E +I + S + K + +
Sbjct: 714 EHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEE 773
Query: 645 R------KELESRALSSKGLKSQLIARLT-KQLKVEEQKEEQKELEKSEKEEDEDDDRKS 697
R K+ E +L ++ + L K++ +E+Q++ KE KE+ E +
Sbjct: 774 RENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKE----SKEKPEKRSQIK 829
Query: 698 EDDKEEEERKRQEEIERQRRERRY-------------ILPDEPAIIVHPNWAAKSGKFDC 744
E D E+ ERK E+ ++ + E + I + H K G+
Sbjct: 830 EKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSK 889
Query: 745 SIMSLSVLLDYRL-------EDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKE 797
+ ++ D + +KE + AE + L + S S EK
Sbjct: 890 NTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKG 949
Query: 798 DKKEKDKK-SKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDS- 855
KEKD++ KK++ +DK+ + + +++ S D +K + ++K KD+
Sbjct: 950 KNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPL 1009
Query: 856 KDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEK 915
K D E+D +D++ DR +E K DK IN K + DK K K
Sbjct: 1010 KTPDGKEKDK-------------KDKDIDR-YKERDKHKDKIQINSLLKLKSEADKPKPK 1055
Query: 916 TQMIT----------INRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLL 965
+ + +N DL+ S L KDLE + H + K
Sbjct: 1056 SSPASKDTRPKEKRLVNDDLMQT------SFERMLSLKDLEIEQW----HKKHKEKIKQK 1105
Query: 966 NKVVLR-ESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEEN 1021
K LR +C K+ D K + ES++ + + + T +++ KD N
Sbjct: 1106 EKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN 1162
Score = 37.7 bits (86), Expect = 0.063
Identities = 55/266 (20%), Positives = 111/266 (41%), Gaps = 20/266 (7%)
Query: 606 KEADGEQDEEEKDDGEAKEI---------STPTHWSKLDPKTMKVND--LRKELESRALS 654
++ D E+ E+E+ E+KE S + +SK + K D L K+ +SR
Sbjct: 909 RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE 968
Query: 655 SKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIER 714
S + + + K+ + + + Q E S KE+ +D+ K+ D KE++ K+ ++I+R
Sbjct: 969 SINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKD--KKDKDIDR 1026
Query: 715 QRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNK---EHSFEVSLFA 771
+ ++ + I ++ KS S D R ++ + + + S
Sbjct: 1027 YKERDKH----KDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFER 1082
Query: 772 ELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRK 831
L + L+ + + +K + EKE + ++ K + K+K + E+ + R K
Sbjct: 1083 MLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSK 1142
Query: 832 SGDDKDKKEDRDERKKEDKRKDDSKD 857
S + D + K + S D
Sbjct: 1143 SSEVTDAYTKEKQPKDAVSNRSQSVD 1168
Score = 37.0 bits (84), Expect = 0.11
Identities = 67/315 (21%), Positives = 119/315 (37%), Gaps = 71/315 (22%)
Query: 834 DDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDE-------YDPMEAEEAEDEEDDRD 886
DD + D +E + + D D ETE+D+ E P+ + E E D D
Sbjct: 308 DDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDD 367
Query: 887 EEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLE 946
+EE+ K D R I R ++R + E EKT
Sbjct: 368 DEEINKMIDDRHILRK-EQRKENEPEAEKT------------------------------ 396
Query: 947 EILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEEN---HEESESLQEDMLGNR 1003
HL Q E FY K + K + + + +ES E+ L N+
Sbjct: 397 --------HLFAKQ-----------EKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNK 437
Query: 1004 LLLPTPTVKQESKDVE-ENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKT 1062
+ + +V E+ + + + V +G G + +KL+ K + E K +EK
Sbjct: 438 KISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELK----QEKE 493
Query: 1063 DEDEKTILNLE-NSNKSLSGELREVKKDLSQLQENLKISENMNLQ-FENQMNKTIRNLST 1120
++ I NL N+ S + RE +++ ++ +L F K+ ++
Sbjct: 494 GKENTRITNLTVNTGLDCSEKTREE----GNFRKSFSPKDDTSLHLFHISTGKSPKHSCG 549
Query: 1121 VMDEIHTVLKKDNVK 1135
+ ++ T LK+++ K
Sbjct: 550 LSEKQSTPLKQEHTK 564
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 66.2 bits (160), Expect = 2e-10
Identities = 61/262 (23%), Positives = 118/262 (45%), Gaps = 35/262 (13%)
Query: 667 TKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDE 726
T+ ++V+ + E + + + + + D +SE + +++ K+ ++IE+ + E+ D
Sbjct: 102 TRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKD- 160
Query: 727 PAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRI 786
+K GK D + +D+ S + A+ N+ ++D
Sbjct: 161 ----------SKKGKKDAE----------KGKDSATESEDEKGGAKKDNKKDKKDSNKGK 200
Query: 787 YKSLLSLPEKEDKKEKDKKSKKDERKDKKE-------ERDDETDEPKPKRRKSGDD-KDK 838
+ S EK ++ KK KKD +K K + D++ DE K GD+ KD
Sbjct: 201 DSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDA 260
Query: 839 KEDRDERKK--EDKRKDDSKD----DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTK 892
K+D E KK +DK+K S D DD +E D + + + E++ D ++ K
Sbjct: 261 KKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAK 320
Query: 893 RDDKRDINRYCKERPSKDKEKE 914
++ K+D + K+ KD++K+
Sbjct: 321 KNAKKDAKKDAKKNAKKDEKKD 342
Score = 56.2 bits (134), Expect = 2e-07
Identities = 39/147 (26%), Positives = 79/147 (53%), Gaps = 20/147 (13%)
Query: 788 KSLLSLPEKEDKKEKD----KKSKKDERKDKKEERDDETDEPKPKRRKSGDDKD--KKED 841
+S L +K+ KK KD K+ K D +KD K+ + D ++ K +S D+K KK++
Sbjct: 131 ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD-AEKGKDSATESEDEKGGAKKDN 189
Query: 842 RDERKKEDKRKDDSKDDD----ETEEDNNQDEYD---------PMEAEEAEDEEDDRDEE 888
+ ++K +K KD + + + TE+D+ + + D ++A +A++++D+ ++
Sbjct: 190 KKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK 249
Query: 889 EMTKRDDKRDINRYCKERPSKDKEKEK 915
+ K D+ +D + KE K+K+K
Sbjct: 250 DANKGDESKDAKKDAKEIKKGKKDKKK 276
Score = 55.1 bits (131), Expect = 4e-07
Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 14/120 (11%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
EK+D+ K +K DE KD K++ + K K++ S D D K+D + K+D KD
Sbjct: 241 EKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDA 300
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
K ++D E E + +D ++ K+D K+D + K+ KD +K+
Sbjct: 301 KK---VAKKDT-----------EKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
Score = 42.0 bits (97), Expect = 0.003
Identities = 43/220 (19%), Positives = 93/220 (42%), Gaps = 27/220 (12%)
Query: 599 EKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGL 658
EKL ++ G++D E+ D + K + K K ++ K+ + + KG
Sbjct: 153 EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGG 212
Query: 659 KSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDR-KSEDDKEEEERKRQEEIERQRR 717
+ + K K + + + K+++++DED + ++ D+ ++ +K +EI++ ++
Sbjct: 213 TEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKK 272
Query: 718 ERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEM 777
+++ P+ K D + E K+ + + A+ E
Sbjct: 273 DKK-----------KPSSTDSDSKD-----------DVKKESKKDATKDAKKVAKKDTEK 310
Query: 778 LQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEE 817
D K +K+ KK+ K +KKDE+KD K++
Sbjct: 311 ESAD----SKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
Score = 40.8 bits (94), Expect = 0.007
Identities = 57/256 (22%), Positives = 106/256 (41%), Gaps = 37/256 (14%)
Query: 610 GEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKE--LESRALSSKGLKSQLIARLT 667
G++ E++ + + + K D K K + KE L+++ S KG K
Sbjct: 115 GKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDA-----E 169
Query: 668 KQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEP 727
K + E++K K + ++D+ D K +D E E ++ + ++ ++
Sbjct: 170 KGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKK------- 222
Query: 728 AIIVHPNWAAKSGKFDCSIMSLSVLLDYRL-EDNKEHSFEVSLFAELFNEMLQRDFGVRI 786
+K GK D +I +V D + ED K+ + + + + + G +
Sbjct: 223 --------DSKKGK-DSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKD 273
Query: 787 YKSLLSLP-------EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKD-- 837
K S +KE KK+ K +KK +KD ++E D + K K K KD
Sbjct: 274 KKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAK-KNAKKDAKKDAK 332
Query: 838 ---KKEDRDERKKEDK 850
KK+++ + KK+ K
Sbjct: 333 KNAKKDEKKDAKKKGK 348
Score = 40.8 bits (94), Expect = 0.007
Identities = 24/123 (19%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 799 KKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDD 858
KK +DK ++KD + E + + D K K + G K+E D +K K K D++
Sbjct: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKG----KEEKLDAKKDSKKGKKDAEKG 171
Query: 859 DETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQM 918
++ ++ ++ + + + ++ ++ ++ T+ + ++ ++ KD +K K
Sbjct: 172 KDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSA 231
Query: 919 ITI 921
I +
Sbjct: 232 IEL 234
Score = 38.1 bits (87), Expect = 0.048
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Query: 801 EKDKKSKKDERK-DKKEERDDETD-EPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDD 858
E D K+ + +K + K + D TD E + K+ K K K ++ + +K D +KD K
Sbjct: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK 165
Query: 859 DETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQ 917
+ E+ + A + ED++ + + DK+D N+ + EK T+
Sbjct: 166 KDAEKGK----------DSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTE 214
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 65.9 bits (159), Expect = 2e-10
Identities = 32/121 (26%), Positives = 67/121 (55%), Gaps = 10/121 (8%)
Query: 796 KEDKKEKDKKSKKDERKDKKE---------ERDDETDEPKPKRRKSGDDKDKKEDRDERK 846
+E +K + + +D+RKD +E E+D E + + K R+ ++ K +DRD+ +
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421
Query: 847 KEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKER 906
++D+ KD KD + E ++ + D E E+ +D+E +R+++ + D+KR ++ +
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRD-KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 480
Query: 907 P 907
P
Sbjct: 481 P 481
Score = 65.1 bits (157), Expect = 4e-10
Identities = 34/124 (27%), Positives = 71/124 (57%), Gaps = 6/124 (4%)
Query: 794 PEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKD 853
P K+ K ++++ K R +++R D ++ K K R D++K+ +R++ ++++K +
Sbjct: 354 PHKKRSKSRERR-KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG 412
Query: 854 DSKD-DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDD----KRDINRYCKERPS 908
+KD D E E+D +D+ E E ++ E DRD+E+ ++D ++D ++ E+
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 909 KDKE 912
KDK+
Sbjct: 473 KDKK 476
Score = 62.4 bits (150), Expect = 2e-09
Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 13/134 (9%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
E+E +KE+ K +D+ ++K E+D E D + + ++ D+DK++++++ K++++ KD
Sbjct: 404 EREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 463
Query: 855 SKDDDETEEDNNQD-----EYDPMEAEEAEDEEDDRDEEEMTKRDDK--RDINRYCKERP 907
SK+ DE + + + Y+ + E R + R + + I R P
Sbjct: 464 SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 523
Query: 908 S------KDKEKEK 915
S KDK++EK
Sbjct: 524 SPRSRNKKDKKREK 537
Score = 61.2 bits (147), Expect = 5e-09
Identities = 31/123 (25%), Positives = 66/123 (53%), Gaps = 9/123 (7%)
Query: 793 LPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRK 852
+ EKE KEKD++ +++ K++++E++ ++ + K R+ +KDK++DR+ ++++ K
Sbjct: 384 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 443
Query: 853 DDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKE 912
D K E++ QD+ E E +D + DE+ + + Y R S+
Sbjct: 444 DRDK-----EKEKEQDK----EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 494
Query: 913 KEK 915
+E+
Sbjct: 495 RER 497
Score = 58.5 bits (140), Expect = 3e-08
Identities = 64/325 (19%), Positives = 135/325 (41%), Gaps = 33/325 (10%)
Query: 582 TRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKV 641
+RS ++ SR + Q + + + ++D K + + +
Sbjct: 316 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR--SKSRERRKSRSRSHS 373
Query: 642 NDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSE-KEEDEDDDRKSEDD 700
D RK+ + + +K + ++ + E +KE +KE E+ + K+ D++ ++ E D
Sbjct: 374 RDKRKDTREKIKEKERVKEK-----DREKEREREKEREKEKERGKNKDRDKEREKDREKD 428
Query: 701 KEEE-ERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLED 759
KE++ ER+R++E E+ R + + D+ K + D S + + R +D
Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDK----------EKEREKDRS----KEIDEKRKKD 474
Query: 760 NKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEK----EDKKEKDKKSKKDERKDKK 815
K + S A + R+ R +S P + K + + +KDKK
Sbjct: 475 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 534
Query: 816 EERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEA 875
E++ + + +R +S + DRD ++K +K K+ + +E D +
Sbjct: 535 REKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEP------DSSVS 588
Query: 876 EEAEDEEDDRDEEEMTKRDDKRDIN 900
+E +D++ R EE + + +N
Sbjct: 589 KEVDDKDAPRTEENKIQHNGNCQLN 613
Score = 56.2 bits (134), Expect = 2e-07
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 10/132 (7%)
Query: 802 KDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKR---KDDSKD- 857
+ + +KD R+ K + + K R +DK++D E+ KE +R KD K+
Sbjct: 340 RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER 399
Query: 858 ------DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDK 911
+ E E N+D E + +D+E DR+ E + + RD + ++ K++
Sbjct: 400 EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Query: 912 EKEKTQMITINR 923
EK++++ I R
Sbjct: 460 EKDRSKEIDEKR 471
Score = 51.6 bits (122), Expect = 4e-06
Identities = 27/124 (21%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERK---KEDKR 851
++ K + + + + K R + + K R+ + + RD+RK ++ K
Sbjct: 327 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 386
Query: 852 KDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDK 911
K+ K+ D +E + E + E E ++++ D++ E+ ++D ++D R ++ KD+
Sbjct: 387 KERVKEKDREKEREREKERE-KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR 445
Query: 912 EKEK 915
+KEK
Sbjct: 446 DKEK 449
Score = 48.9 bits (115), Expect = 3e-05
Identities = 54/273 (19%), Positives = 109/273 (39%), Gaps = 57/273 (20%)
Query: 649 ESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKR 708
+ R+ S + KS+ + + K +K ++KE K EK+ +++ +R+ E +KE+E K
Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK-EKDREKEREREKEREKEKERGKN 414
Query: 709 QEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVS 768
++ + + ++R D+ D E KEH +
Sbjct: 415 KDRDKEREKDRE---KDKEK-------------------------DREREREKEHEKD-- 444
Query: 769 LFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPK 828
RD EKE +++K+K+ +KD K+ E+R + P
Sbjct: 445 -----------RD------------KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 829 RRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDE-EDDRDE 887
R + + + R+ R++ + S +T + + P + + + E +RD
Sbjct: 482 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH 541
Query: 888 -EEMTKRDDKRDINRYCKERPSKDK-EKEKTQM 918
E +R+ + + +R K+K EK T +
Sbjct: 542 ISERRERERSTSMRKSSNDRDGKEKLEKNSTSL 574
Score = 47.0 bits (110), Expect = 1e-04
Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 2/121 (1%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
+ + + K+ + K + + K +RR K + + R+ RK +
Sbjct: 315 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSR 374
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
K D E+ ++ + E+ + E +R++E+ ++ RD R K+R KDKEK+
Sbjct: 375 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE-KDR-EKDKEKD 432
Query: 915 K 915
+
Sbjct: 433 R 433
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/280 (18%), Positives = 107/280 (38%), Gaps = 42/280 (15%)
Query: 632 SKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE 691
SK K + R++ SR+ S K K+ E+ +E+++E EK ++E E
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 410
Query: 692 DDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSV 751
K D + E++R++ +E +R+R + D
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK----------------------- 447
Query: 752 LLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDER 811
+ E +KE E E+ +E ++D K + P + + + S ++ R
Sbjct: 448 --EKEKEQDKEKEREKDRSKEI-DEKRKKD------KKSRTPPRSYNASRRSRSSSRERR 498
Query: 812 KDKKEERDDETDEPKP-KRRKSGDDKDKKEDRDERKKE------DKRKDDSKDDDETEED 864
+ + K KR+ S + ++ ++K+E +R++ + +
Sbjct: 499 RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSS 558
Query: 865 NNQDEYDPMEAEEA---EDEEDDRDEEEMTKRDDKRDINR 901
N++D + +E E E + + ++K D +D R
Sbjct: 559 NDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 598
Score = 42.4 bits (98), Expect = 0.003
Identities = 21/45 (46%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
+R +RSR R+++RRRS+ SP +KRS+ R R+ R RS R +R
Sbjct: 335 SRSHNRSRSRQKDRRRSK--SPHKKRSKSRERRKSRSRSHSRDKR 377
Score = 39.3 bits (90), Expect = 0.022
Identities = 16/48 (33%), Positives = 29/48 (60%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
++V + ++ RERE+ER + +ER + R +ER RE+++ R R
Sbjct: 388 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435
Score = 38.5 bits (88), Expect = 0.037
Identities = 15/56 (26%), Positives = 31/56 (55%)
Query: 303 GRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRV 358
G+N D+ + ++ +E++RER R +E R + +E+ +E+ER R + +
Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 467
Score = 37.7 bits (86), Expect = 0.063
Identities = 14/53 (26%), Positives = 31/53 (58%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R D+ R+ DR +++E++R R RE+ ++ R +E+ +++E+ + R
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 463
Score = 37.4 bits (85), Expect = 0.083
Identities = 28/146 (19%), Positives = 66/146 (45%), Gaps = 7/146 (4%)
Query: 771 AELFNEMLQRDFGVRIYKSLLSLP-EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKR 829
A+ E+++R VR +S +S E E K ++K + + + R + KR
Sbjct: 272 AKELEEVMKR---VREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKR 328
Query: 830 RKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEE 889
+S + + +R +++D+R+ SK + + + + + +D R++ +
Sbjct: 329 SQS-KHRSRSHNRSRSRQKDRRR--SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 385
Query: 890 MTKRDDKRDINRYCKERPSKDKEKEK 915
+R ++D + + ++KEKE+
Sbjct: 386 EKERVKEKDREKEREREKEREKEKER 411
Score = 37.0 bits (84), Expect = 0.11
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 266 QPLLQQPQQKAGLLQPPVRIVSQPQP--ARRLDPPS-----RFSGRNDRGDQVPNRKDDR 318
+P PQ A L+ ++ V + Q + ++P S R GR+ + +R +
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 321
Query: 319 SRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
S R R+R +S+ RS RSR R R R +SP + R
Sbjct: 322 SHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 358
Score = 37.0 bits (84), Expect = 0.11
Identities = 13/47 (27%), Positives = 30/47 (63%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERER 350
R D +++ ++ + ++RE+ER R +ER +++R + + +ERE+
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK 423
Score = 37.0 bits (84), Expect = 0.11
Identities = 15/41 (36%), Positives = 27/41 (65%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
RKD R + +E+ER + ++R +R+R +ER +ER ++ R
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 417
Score = 37.0 bits (84), Expect = 0.11
Identities = 14/44 (31%), Positives = 28/44 (63%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
+R+ +R RE+ERE+ + R ++ R + RE+ +++E+ R R
Sbjct: 394 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437
Score = 36.6 bits (83), Expect = 0.14
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 15/83 (18%)
Query: 287 SQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRS---------------RE 331
SQ + R SR ++ R + P++K +SRER + R RS +E
Sbjct: 329 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKE 388
Query: 332 RSPQRKRSRERSPRRERERSPRR 354
R ++ R +ER +ERE+ R
Sbjct: 389 RVKEKDREKEREREKEREKEKER 411
Score = 35.4 bits (80), Expect = 0.31
Identities = 17/58 (29%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 299 SRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
SR R+ R D K+ + R +E++R + RER +R++ +ER ++R++ + R
Sbjct: 369 SRSHSRDKRKDTREKIKE-KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 425
Score = 35.4 bits (80), Expect = 0.31
Identities = 14/61 (22%), Positives = 32/61 (52%)
Query: 294 RLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPR 353
R+ R R ++ ++ ++++R++ER + RE+ ++ R RER E++R
Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 448
Query: 354 R 354
+
Sbjct: 449 K 449
Score = 35.4 bits (80), Expect = 0.31
Identities = 16/52 (30%), Positives = 32/52 (61%), Gaps = 4/52 (7%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPR----RERERSPRRVR 356
D+ R+ ++ RE+E+ER ++++R +R++ RE+ RERE+ + R
Sbjct: 394 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR 445
Score = 35.4 bits (80), Expect = 0.31
Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 17/85 (20%)
Query: 293 RRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQ------RKRSRERSPR- 345
R+ D SR R+ + R SRER R R RS RSP+ RK SR SPR
Sbjct: 471 RKKDKKSRTPPRSYNASR---RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS 527
Query: 346 -------RERERSPRRVRRVVPRYT 363
RE+ER RR R T
Sbjct: 528 RNKKDKKREKERDHISERRERERST 552
Score = 33.9 bits (76), Expect = 0.91
Identities = 15/60 (25%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 293 RRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRR--SRERSPQRKRSRERSPRRERER 350
+R D + + ++ ++ +R +ERE+E+ R +++R +R++ RE+ ++RER
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435
Score = 33.9 bits (76), Expect = 0.91
Identities = 12/51 (23%), Positives = 29/51 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R ++ R ++ R++ERE+ R +++ R+R RE+ ++R++ +
Sbjct: 401 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 451
Score = 33.1 bits (74), Expect = 1.6
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 309 DQVPNRKDDRSRERERERRRSRE-RSPQRKRS---RERSPRRERERSPRRVRRVVPRYTV 364
D+ R+ DRS+E + +R++ ++ R+P R + R RS RER R R PR +
Sbjct: 454 DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 513
Query: 365 QFSKFSLDCPS 375
+ S PS
Sbjct: 514 TIKRKSSRSPS 524
Score = 32.7 bits (73), Expect = 2.0
Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 6/55 (10%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRE-RSPRR-----ERERSPRRVRR 357
D+ ++ ++ +E+ERE+ RS+E +RK+ ++ R+P R R RS R RR
Sbjct: 444 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 498
Score = 32.0 bits (71), Expect = 3.5
Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Query: 309 DQVPNRKDDRSRERE--RERRRSRERSPQRKRSRERSPRRERERSPRR 354
D+ +++ DR RERE E+ R +E+ ++ + +ER R +E +R
Sbjct: 424 DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 471
Score = 31.6 bits (70), Expect = 4.5
Identities = 9/40 (22%), Positives = 28/40 (70%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPR 353
++ ++ R++E+E+ + +E+ ++ RS+E +R++++ R
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 65.9 bits (159), Expect = 2e-10
Identities = 32/121 (26%), Positives = 67/121 (55%), Gaps = 10/121 (8%)
Query: 796 KEDKKEKDKKSKKDERKDKKE---------ERDDETDEPKPKRRKSGDDKDKKEDRDERK 846
+E +K + + +D+RKD +E E+D E + + K R+ ++ K +DRD+ +
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305
Query: 847 KEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKER 906
++D+ KD KD + E ++ + D E E+ +D+E +R+++ + D+KR ++ +
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRD-KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 364
Query: 907 P 907
P
Sbjct: 365 P 365
Score = 65.1 bits (157), Expect = 4e-10
Identities = 34/124 (27%), Positives = 71/124 (57%), Gaps = 6/124 (4%)
Query: 794 PEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKD 853
P K+ K ++++ K R +++R D ++ K K R D++K+ +R++ ++++K +
Sbjct: 238 PHKKRSKSRERR-KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG 296
Query: 854 DSKD-DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDD----KRDINRYCKERPS 908
+KD D E E+D +D+ E E ++ E DRD+E+ ++D ++D ++ E+
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 909 KDKE 912
KDK+
Sbjct: 357 KDKK 360
Score = 62.4 bits (150), Expect = 2e-09
Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 13/134 (9%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
E+E +KE+ K +D+ ++K E+D E D + + ++ D+DK++++++ K++++ KD
Sbjct: 288 EREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 347
Query: 855 SKDDDETEEDNNQD-----EYDPMEAEEAEDEEDDRDEEEMTKRDDK--RDINRYCKERP 907
SK+ DE + + + Y+ + E R + R + + I R P
Sbjct: 348 SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 407
Query: 908 S------KDKEKEK 915
S KDK++EK
Sbjct: 408 SPRSRNKKDKKREK 421
Score = 61.2 bits (147), Expect = 5e-09
Identities = 31/123 (25%), Positives = 66/123 (53%), Gaps = 9/123 (7%)
Query: 793 LPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRK 852
+ EKE KEKD++ +++ K++++E++ ++ + K R+ +KDK++DR+ ++++ K
Sbjct: 268 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 327
Query: 853 DDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKE 912
D K E++ QD+ E E +D + DE+ + + Y R S+
Sbjct: 328 DRDK-----EKEKEQDK----EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 378
Query: 913 KEK 915
+E+
Sbjct: 379 RER 381
Score = 58.5 bits (140), Expect = 3e-08
Identities = 64/325 (19%), Positives = 135/325 (41%), Gaps = 33/325 (10%)
Query: 582 TRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKV 641
+RS ++ SR + Q + + + ++D K + + +
Sbjct: 200 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR--SKSRERRKSRSRSHS 257
Query: 642 NDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSE-KEEDEDDDRKSEDD 700
D RK+ + + +K + ++ + E +KE +KE E+ + K+ D++ ++ E D
Sbjct: 258 RDKRKDTREKIKEKERVKEK-----DREKEREREKEREKEKERGKNKDRDKEREKDREKD 312
Query: 701 KEEE-ERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLED 759
KE++ ER+R++E E+ R + + D+ K + D S + + R +D
Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDK----------EKEREKDRS----KEIDEKRKKD 358
Query: 760 NKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEK----EDKKEKDKKSKKDERKDKK 815
K + S A + R+ R +S P + K + + +KDKK
Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 418
Query: 816 EERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEA 875
E++ + + +R +S + DRD ++K +K K+ + +E D +
Sbjct: 419 REKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEP------DSSVS 472
Query: 876 EEAEDEEDDRDEEEMTKRDDKRDIN 900
+E +D++ R EE + + +N
Sbjct: 473 KEVDDKDAPRTEENKIQHNGNCQLN 497
Score = 56.2 bits (134), Expect = 2e-07
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 10/132 (7%)
Query: 802 KDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKR---KDDSKD- 857
+ + +KD R+ K + + K R +DK++D E+ KE +R KD K+
Sbjct: 224 RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER 283
Query: 858 ------DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDK 911
+ E E N+D E + +D+E DR+ E + + RD + ++ K++
Sbjct: 284 EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343
Query: 912 EKEKTQMITINR 923
EK++++ I R
Sbjct: 344 EKDRSKEIDEKR 355
Score = 51.6 bits (122), Expect = 4e-06
Identities = 27/124 (21%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERK---KEDKR 851
++ K + + + + K R + + K R+ + + RD+RK ++ K
Sbjct: 211 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 270
Query: 852 KDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDK 911
K+ K+ D +E + E + E E ++++ D++ E+ ++D ++D R ++ KD+
Sbjct: 271 KERVKEKDREKEREREKERE-KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR 329
Query: 912 EKEK 915
+KEK
Sbjct: 330 DKEK 333
Score = 48.9 bits (115), Expect = 3e-05
Identities = 54/273 (19%), Positives = 109/273 (39%), Gaps = 57/273 (20%)
Query: 649 ESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKR 708
+ R+ S + KS+ + + K +K ++KE K EK+ +++ +R+ E +KE+E K
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK-EKDREKEREREKEREKEKERGKN 298
Query: 709 QEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVS 768
++ + + ++R D+ D E KEH +
Sbjct: 299 KDRDKEREKDRE---KDKEK-------------------------DREREREKEHEKD-- 328
Query: 769 LFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPK 828
RD EKE +++K+K+ +KD K+ E+R + P
Sbjct: 329 -----------RD------------KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 829 RRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDE-EDDRDE 887
R + + + R+ R++ + S +T + + P + + + E +RD
Sbjct: 366 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH 425
Query: 888 -EEMTKRDDKRDINRYCKERPSKDK-EKEKTQM 918
E +R+ + + +R K+K EK T +
Sbjct: 426 ISERRERERSTSMRKSSNDRDGKEKLEKNSTSL 458
Score = 47.0 bits (110), Expect = 1e-04
Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 2/121 (1%)
Query: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
+ + + K+ + K + + K +RR K + + R+ RK +
Sbjct: 199 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSR 258
Query: 855 SKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
K D E+ ++ + E+ + E +R++E+ ++ RD R K+R KDKEK+
Sbjct: 259 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE-KDR-EKDKEKD 316
Query: 915 K 915
+
Sbjct: 317 R 317
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/280 (18%), Positives = 107/280 (38%), Gaps = 42/280 (15%)
Query: 632 SKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE 691
SK K + R++ SR+ S K K+ E+ +E+++E EK ++E E
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 294
Query: 692 DDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSV 751
K D + E++R++ +E +R+R + D
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK----------------------- 331
Query: 752 LLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDER 811
+ E +KE E E+ +E ++D K + P + + + S ++ R
Sbjct: 332 --EKEKEQDKEKEREKDRSKEI-DEKRKKD------KKSRTPPRSYNASRRSRSSSRERR 382
Query: 812 KDKKEERDDETDEPKP-KRRKSGDDKDKKEDRDERKKE------DKRKDDSKDDDETEED 864
+ + K KR+ S + ++ ++K+E +R++ + +
Sbjct: 383 RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSS 442
Query: 865 NNQDEYDPMEAEEA---EDEEDDRDEEEMTKRDDKRDINR 901
N++D + +E E E + + ++K D +D R
Sbjct: 443 NDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 482
Score = 42.4 bits (98), Expect = 0.003
Identities = 21/45 (46%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRR 357
+R +RSR R+++RRRS+ SP +KRS+ R R+ R RS R +R
Sbjct: 219 SRSHNRSRSRQKDRRRSK--SPHKKRSKSRERRKSRSRSHSRDKR 261
Score = 39.3 bits (90), Expect = 0.022
Identities = 16/48 (33%), Positives = 29/48 (60%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
++V + ++ RERE+ER + +ER + R +ER RE+++ R R
Sbjct: 272 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319
Score = 38.5 bits (88), Expect = 0.037
Identities = 15/56 (26%), Positives = 31/56 (55%)
Query: 303 GRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRV 358
G+N D+ + ++ +E++RER R +E R + +E+ +E+ER R + +
Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 351
Score = 37.7 bits (86), Expect = 0.063
Identities = 14/53 (26%), Positives = 31/53 (58%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
R D+ R+ DR +++E++R R RE+ ++ R +E+ +++E+ + R
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 347
Score = 37.4 bits (85), Expect = 0.083
Identities = 28/146 (19%), Positives = 66/146 (45%), Gaps = 7/146 (4%)
Query: 771 AELFNEMLQRDFGVRIYKSLLSLP-EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKR 829
A+ E+++R VR +S +S E E K ++K + + + R + KR
Sbjct: 156 AKELEEVMKR---VREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKR 212
Query: 830 RKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEE 889
+S + + +R +++D+R+ SK + + + + + +D R++ +
Sbjct: 213 SQS-KHRSRSHNRSRSRQKDRRR--SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 269
Query: 890 MTKRDDKRDINRYCKERPSKDKEKEK 915
+R ++D + + ++KEKE+
Sbjct: 270 EKERVKEKDREKEREREKEREKEKER 295
Score = 37.0 bits (84), Expect = 0.11
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 266 QPLLQQPQQKAGLLQPPVRIVSQPQP--ARRLDPPS-----RFSGRNDRGDQVPNRKDDR 318
+P PQ A L+ ++ V + Q + ++P S R GR+ + +R +
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 205
Query: 319 SRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
S R R+R +S+ RS RSR R R R +SP + R
Sbjct: 206 SHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 242
Score = 37.0 bits (84), Expect = 0.11
Identities = 13/47 (27%), Positives = 30/47 (63%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERER 350
R D +++ ++ + ++RE+ER R +ER +++R + + +ERE+
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK 307
Score = 37.0 bits (84), Expect = 0.11
Identities = 15/41 (36%), Positives = 27/41 (65%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
RKD R + +E+ER + ++R +R+R +ER +ER ++ R
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 301
Score = 37.0 bits (84), Expect = 0.11
Identities = 14/44 (31%), Positives = 28/44 (63%)
Query: 313 NRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
+R+ +R RE+ERE+ + R ++ R + RE+ +++E+ R R
Sbjct: 278 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321
Score = 36.6 bits (83), Expect = 0.14
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 15/83 (18%)
Query: 287 SQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRS---------------RE 331
SQ + R SR ++ R + P++K +SRER + R RS +E
Sbjct: 213 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKE 272
Query: 332 RSPQRKRSRERSPRRERERSPRR 354
R ++ R +ER +ERE+ R
Sbjct: 273 RVKEKDREKEREREKEREKEKER 295
Score = 35.4 bits (80), Expect = 0.31
Identities = 17/58 (29%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 299 SRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVR 356
SR R+ R D K+ + R +E++R + RER +R++ +ER ++R++ + R
Sbjct: 253 SRSHSRDKRKDTREKIKE-KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 309
Score = 35.4 bits (80), Expect = 0.31
Identities = 14/61 (22%), Positives = 32/61 (52%)
Query: 294 RLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPR 353
R+ R R ++ ++ ++++R++ER + RE+ ++ R RER E++R
Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 332
Query: 354 R 354
+
Sbjct: 333 K 333
Score = 35.4 bits (80), Expect = 0.31
Identities = 16/52 (30%), Positives = 32/52 (61%), Gaps = 4/52 (7%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPR----RERERSPRRVR 356
D+ R+ ++ RE+E+ER ++++R +R++ RE+ RERE+ + R
Sbjct: 278 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR 329
Score = 35.4 bits (80), Expect = 0.31
Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 17/85 (20%)
Query: 293 RRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQ------RKRSRERSPR- 345
R+ D SR R+ + R SRER R R RS RSP+ RK SR SPR
Sbjct: 355 RKKDKKSRTPPRSYNASR---RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS 411
Query: 346 -------RERERSPRRVRRVVPRYT 363
RE+ER RR R T
Sbjct: 412 RNKKDKKREKERDHISERRERERST 436
Score = 33.9 bits (76), Expect = 0.91
Identities = 15/60 (25%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 293 RRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRR--SRERSPQRKRSRERSPRRERER 350
+R D + + ++ ++ +R +ERE+E+ R +++R +R++ RE+ ++RER
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319
Score = 33.9 bits (76), Expect = 0.91
Identities = 12/51 (23%), Positives = 29/51 (56%)
Query: 304 RNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRR 354
R ++ R ++ R++ERE+ R +++ R+R RE+ ++R++ +
Sbjct: 285 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 335
Score = 33.1 bits (74), Expect = 1.6
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 309 DQVPNRKDDRSRERERERRRSRE-RSPQRKRS---RERSPRRERERSPRRVRRVVPRYTV 364
D+ R+ DRS+E + +R++ ++ R+P R + R RS RER R R PR +
Sbjct: 338 DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 397
Query: 365 QFSKFSLDCPS 375
+ S PS
Sbjct: 398 TIKRKSSRSPS 408
Score = 32.7 bits (73), Expect = 2.0
Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 6/55 (10%)
Query: 309 DQVPNRKDDRSRERERERRRSRERSPQRKRSRE-RSPRR-----ERERSPRRVRR 357
D+ ++ ++ +E+ERE+ RS+E +RK+ ++ R+P R R RS R RR
Sbjct: 328 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 382
Score = 32.0 bits (71), Expect = 3.5
Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Query: 309 DQVPNRKDDRSRERE--RERRRSRERSPQRKRSRERSPRRERERSPRR 354
D+ +++ DR RERE E+ R +E+ ++ + +ER R +E +R
Sbjct: 308 DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 355
Score = 31.6 bits (70), Expect = 4.5
Identities = 9/40 (22%), Positives = 28/40 (70%)
Query: 314 RKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPR 353
++ ++ R++E+E+ + +E+ ++ RS+E +R++++ R
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 362
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,280,876
Number of Sequences: 37866
Number of extensions: 2599097
Number of successful extensions: 92020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1155
Number of HSP's successfully gapped in prelim test: 1153
Number of HSP's that attempted gapping in prelim test: 21387
Number of HSP's gapped (non-prelim): 32535
length of query: 1150
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1037
effective length of database: 13,968,660
effective search space: 14485500420
effective search space used: 14485500420
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.