BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|46487911 zinc finger protein 406 isoform ZFAT-1 [Homo sapiens] (1243 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|46487911 zinc finger protein 406 isoform ZFAT-1 [Homo sapiens] 2548 0.0 gi|71480169 zinc finger protein 406 isoform TR-ZFAT [Homo sapiens] 1673 0.0 gi|156627573 zinc finger protein 836 [Homo sapiens] 145 3e-34 gi|239747149 PREDICTED: hypothetical protein XP_002343926 isofor... 143 9e-34 gi|239747147 PREDICTED: hypothetical protein XP_002343925 isofor... 143 9e-34 gi|239747145 PREDICTED: hypothetical protein XP_002343927 isofor... 143 9e-34 gi|188497655 zinc finger protein 84 [Homo sapiens] 143 9e-34 gi|188497653 zinc finger protein 84 [Homo sapiens] 143 9e-34 gi|157167158 zinc finger protein 808 [Homo sapiens] 143 9e-34 gi|57165428 zinc finger protein 28 [Homo sapiens] 143 1e-33 gi|169213999 PREDICTED: similar to hCG1778601 isoform 1 [Homo sa... 142 2e-33 gi|169214410 PREDICTED: similar to hCG1778601 isoform 1 [Homo sa... 142 2e-33 gi|169213416 PREDICTED: hypothetical protein LOC388559 [Homo sap... 142 2e-33 gi|72384365 zinc finger protein 816A [Homo sapiens] 141 4e-33 gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi... 140 8e-33 gi|38708324 zinc finger protein 93 [Homo sapiens] 140 8e-33 gi|148727251 zinc finger protein 81 [Homo sapiens] 140 8e-33 gi|48717244 zinc finger protein 782 [Homo sapiens] 140 1e-32 gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens] 139 1e-32 gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens] 139 1e-32 gi|162417982 zinc finger protein 64 isoform d [Homo sapiens] 139 2e-32 gi|210031219 zinc finger protein 845 [Homo sapiens] 139 2e-32 gi|61676195 zinc finger protein 320 [Homo sapiens] 137 6e-32 gi|34303941 zinc finger protein 567 [Homo sapiens] 137 8e-32 gi|57165430 zinc finger protein ZNF468 isoform 1 [Homo sapiens] 136 1e-31 gi|57165432 zinc finger protein ZNF468 isoform 2 [Homo sapiens] 136 1e-31 gi|48717241 zinc finger protein 425 [Homo sapiens] 136 1e-31 gi|221307571 zinc finger protein 234 [Homo sapiens] 135 2e-31 gi|24307913 zinc finger protein 234 [Homo sapiens] 135 2e-31 gi|209954795 zinc finger protein 761 [Homo sapiens] 135 2e-31 >gi|46487911 zinc finger protein 406 isoform ZFAT-1 [Homo sapiens] Length = 1243 Score = 2548 bits (6605), Expect = 0.0 Identities = 1243/1243 (100%), Positives = 1243/1243 (100%) Query: 1 METRAAENTAIFMCKCCNLFSPNQSELLSHVSEKHMEEGVNVDEIIIPLRPLSTPEPPNS 60 METRAAENTAIFMCKCCNLFSPNQSELLSHVSEKHMEEGVNVDEIIIPLRPLSTPEPPNS Sbjct: 1 METRAAENTAIFMCKCCNLFSPNQSELLSHVSEKHMEEGVNVDEIIIPLRPLSTPEPPNS 60 Query: 61 SKTGDEFLVMKRKRGRPKGSTKKSSTEEELAENIVSPTEDSPLAPEEGNSLPPSSLECSK 120 SKTGDEFLVMKRKRGRPKGSTKKSSTEEELAENIVSPTEDSPLAPEEGNSLPPSSLECSK Sbjct: 61 SKTGDEFLVMKRKRGRPKGSTKKSSTEEELAENIVSPTEDSPLAPEEGNSLPPSSLECSK 120 Query: 121 CCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELEKKCKEDDREKASKRPRSQKTEK 180 CCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELEKKCKEDDREKASKRPRSQKTEK Sbjct: 121 CCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELEKKCKEDDREKASKRPRSQKTEK 180 Query: 181 VQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSADLVP 240 VQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSADLVP Sbjct: 181 VQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSADLVP 240 Query: 241 RRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYK 300 RRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYK Sbjct: 241 RRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYK 300 Query: 301 CPQCSYASAIKANLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCK 360 CPQCSYASAIKANLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCK Sbjct: 301 CPQCSYASAIKANLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCK 360 Query: 361 KKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRD 420 KKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRD Sbjct: 361 KKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRD 420 Query: 421 RHMLVHGDKWPFACELCGHGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEV 480 RHMLVHGDKWPFACELCGHGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEV Sbjct: 421 RHMLVHGDKWPFACELCGHGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEV 480 Query: 481 HGAAQEALVFTSSINQSFCLLEPGGDIQQEALGDQLQLVEEEFALQGVNALKEEACPGDT 540 HGAAQEALVFTSSINQSFCLLEPGGDIQQEALGDQLQLVEEEFALQGVNALKEEACPGDT Sbjct: 481 HGAAQEALVFTSSINQSFCLLEPGGDIQQEALGDQLQLVEEEFALQGVNALKEEACPGDT 540 Query: 541 QLEEGRKEPEAPGEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLK 600 QLEEGRKEPEAPGEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLK Sbjct: 541 QLEEGRKEPEAPGEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLK 600 Query: 601 NDTSSAEAHAAPEKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNM 660 NDTSSAEAHAAPEKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNM Sbjct: 601 NDTSSAEAHAAPEKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNM 660 Query: 661 AVLSAGDPDPSRCLRSNPAEASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLN 720 AVLSAGDPDPSRCLRSNPAEASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLN Sbjct: 661 AVLSAGDPDPSRCLRSNPAEASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLN 720 Query: 721 SLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSI 780 SLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSI Sbjct: 721 SLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSI 780 Query: 781 TKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFS 840 TKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFS Sbjct: 781 TKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFS 840 Query: 841 EDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHI 900 EDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHI Sbjct: 841 EDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHI 900 Query: 901 WAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHT 960 WAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHT Sbjct: 901 WAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHT 960 Query: 961 ADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE 1020 ADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE Sbjct: 961 ADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE 1020 Query: 1021 EYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPKWETA 1080 EYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPKWETA Sbjct: 1021 EYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPKWETA 1080 Query: 1081 TEAPEEPSTQYLHITEAEEDVQGTQAAVAALQDLRYTSESGDRLDPTAVNILQQIIELGA 1140 TEAPEEPSTQYLHITEAEEDVQGTQAAVAALQDLRYTSESGDRLDPTAVNILQQIIELGA Sbjct: 1081 TEAPEEPSTQYLHITEAEEDVQGTQAAVAALQDLRYTSESGDRLDPTAVNILQQIIELGA 1140 Query: 1141 ETHDATALASVVAMAPGTVTVVKQVTEEEPSSNHTVMIQETVQQASVELAEQHHLVVSSD 1200 ETHDATALASVVAMAPGTVTVVKQVTEEEPSSNHTVMIQETVQQASVELAEQHHLVVSSD Sbjct: 1141 ETHDATALASVVAMAPGTVTVVKQVTEEEPSSNHTVMIQETVQQASVELAEQHHLVVSSD 1200 Query: 1201 DVEGIETVTVYTQGGEASEFIVYVQEAMQPVEEQAVEQPAQEL 1243 DVEGIETVTVYTQGGEASEFIVYVQEAMQPVEEQAVEQPAQEL Sbjct: 1201 DVEGIETVTVYTQGGEASEFIVYVQEAMQPVEEQAVEQPAQEL 1243 >gi|71480169 zinc finger protein 406 isoform TR-ZFAT [Homo sapiens] Length = 846 Score = 1673 bits (4332), Expect = 0.0 Identities = 813/813 (100%), Positives = 813/813 (100%) Query: 13 MCKCCNLFSPNQSELLSHVSEKHMEEGVNVDEIIIPLRPLSTPEPPNSSKTGDEFLVMKR 72 MCKCCNLFSPNQSELLSHVSEKHMEEGVNVDEIIIPLRPLSTPEPPNSSKTGDEFLVMKR Sbjct: 1 MCKCCNLFSPNQSELLSHVSEKHMEEGVNVDEIIIPLRPLSTPEPPNSSKTGDEFLVMKR 60 Query: 73 KRGRPKGSTKKSSTEEELAENIVSPTEDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLR 132 KRGRPKGSTKKSSTEEELAENIVSPTEDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLR Sbjct: 61 KRGRPKGSTKKSSTEEELAENIVSPTEDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLR 120 Query: 133 KHICIIVLNLGEEEGEAGNESDLELEKKCKEDDREKASKRPRSQKTEKVQKISGKEARQL 192 KHICIIVLNLGEEEGEAGNESDLELEKKCKEDDREKASKRPRSQKTEKVQKISGKEARQL Sbjct: 121 KHICIIVLNLGEEEGEAGNESDLELEKKCKEDDREKASKRPRSQKTEKVQKISGKEARQL 180 Query: 193 SGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQT 252 SGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQT Sbjct: 181 SGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQT 240 Query: 253 PYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKA 312 PYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKA Sbjct: 241 PYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKA 300 Query: 313 NLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH 372 NLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH Sbjct: 301 NLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH 360 Query: 373 IRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPF 432 IRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPF Sbjct: 361 IRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPF 420 Query: 433 ACELCGHGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEVHGAAQEALVFTS 492 ACELCGHGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEVHGAAQEALVFTS Sbjct: 421 ACELCGHGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEVHGAAQEALVFTS 480 Query: 493 SINQSFCLLEPGGDIQQEALGDQLQLVEEEFALQGVNALKEEACPGDTQLEEGRKEPEAP 552 SINQSFCLLEPGGDIQQEALGDQLQLVEEEFALQGVNALKEEACPGDTQLEEGRKEPEAP Sbjct: 481 SINQSFCLLEPGGDIQQEALGDQLQLVEEEFALQGVNALKEEACPGDTQLEEGRKEPEAP 540 Query: 553 GEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLKNDTSSAEAHAAP 612 GEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLKNDTSSAEAHAAP Sbjct: 541 GEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLKNDTSSAEAHAAP 600 Query: 613 EKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNMAVLSAGDPDPSR 672 EKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNMAVLSAGDPDPSR Sbjct: 601 EKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNMAVLSAGDPDPSR 660 Query: 673 CLRSNPAEASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLC 732 CLRSNPAEASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLC Sbjct: 661 CLRSNPAEASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLC 720 Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK Sbjct: 721 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 780 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTAL 825 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTAL Sbjct: 781 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTAL 813 Score = 108 bits (270), Expect = 3e-23 Identities = 103/420 (24%), Positives = 177/420 (42%), Gaps = 29/420 (6%) Query: 548 EPEAPGEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLKNDTSSAE 607 E E + +P E +LPP LE + +++++ ++ + E Sbjct: 75 EEELAENIVSPTEDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEE 134 Query: 608 AHAAPEKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNMAVLSAGD 667 A E +++ + + KA Q++ Q G+ + + A Sbjct: 135 GEAGNESDLELEKKCKEDDR--------EKASKRPRSQKTEKVQKISGK-EARQLSGAKK 185 Query: 668 PDPSRCLRSNPA--EASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLNSLQKK 725 P S L ++ A A+ ++P AG +T ++ A R G + ++ Sbjct: 186 PIISVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQP 245 Query: 726 QMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCL 785 ++ L K++ CEYC K+F ++ H+R HT E Y C QC Y+S K L Sbjct: 246 MKSSRLGPTQLKIF---TCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANL 302 Query: 786 KRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHL-KVHTALDKRSYSCPVCEKSFSEDRL 844 H ++KH+ C D C ++ K L+ H+ +VH + + C C+K +S+ + Sbjct: 303 NVH-LRKHTGEKFAC--DYCSFTCLSKGHLKVHIERVHKKIKQH---CRFCKKKYSDVKN 356 Query: 845 IKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAM--KCPYCDFYFMKNGSDLQRHIWA 902 + HI+ H + + E L + L GKR + C C+ F KN D RH+ Sbjct: 357 LIKHIRDAH-DPQDKKVKEALDE-LCLMTREGKRQLLYDCHICERKF-KNELDRDRHMLV 413 Query: 903 HEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSH-KLLHTA 961 H PF C LC + L+ H+ +H ++C +C KKF S L++H K +H A Sbjct: 414 HGDKWPFACELCGHGATKYQALELHVRKHPF--VYVCAVCRKKFVSSIRLRTHIKEVHGA 471 Score = 67.4 bits (163), Expect = 8e-11 Identities = 60/233 (25%), Positives = 81/233 (34%), Gaps = 72/233 (30%) Query: 882 CPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDM 941 C YC+ F K LQ H+ H KP+KC C YA+ K+NL H+ +H+ EK CD Sbjct: 261 CEYCNKVF-KFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDY 318 Query: 942 CGKKFKSKGTLKSH---------------------------------------------- 955 C SKG LK H Sbjct: 319 CSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDE 378 Query: 956 KLLHTADGKQ---FKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L T +GK+ + C +C+ + RHM H PF C C + +L+ H Sbjct: 379 LCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELH 438 Query: 1013 YNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHG 1065 RKHP + V C VC + + H+K HG Sbjct: 439 V-RKHP---FVYV-----------------CAVCRKKFVSSIRLRTHIKEVHG 470 Score = 66.6 bits (161), Expect = 1e-10 Identities = 83/391 (21%), Positives = 146/391 (37%), Gaps = 36/391 (9%) Query: 1 METRAAENTAIFMCKCCNLFSPNQSELLSHVSEKH---MEEGVNVDEIIIPLRPLSTPEP 57 +E ++ +++C C + L +H+ E H E V I L Sbjct: 435 LELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEVHGAAQEALVFTSSINQSFCLLEPGGD 494 Query: 58 PNSSKTGDEFLVMKR----------KRGRPKGST--KKSSTEEELAENIVSPTEDSPLAP 105 GD+ +++ K G T ++ E E + +P Sbjct: 495 IQQEALGDQLQLVEEEFALQGVNALKEEACPGDTQLEEGRKEPEAPGEMPAPAVHLASPQ 554 Query: 106 EEGNSLPPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELEKKCKEDD 165 E +LPP LE + +++++ ++ + E A E +++ + Sbjct: 555 AESTALPPCELETTVVSSSDLHSQEVVSDDFLLKNDTSSAEAHAAPEKPPDMQHRSSVQT 614 Query: 166 R--------EKASKRPRSQKTEKVQKISGK-EARQLSGAKKPIISVVLTAHEAIPGATKI 216 + KA Q++ Q G+ + + A P S L ++ A A+ + Sbjct: 615 QGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNMAVLSAGDPDPSRCLRSNPA--EASDL 672 Query: 217 VPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIF---TC 273 +P AG +T ++ A R G + ++ ++ L K++ C Sbjct: 673 LPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLCERIRKVYGDLEC 732 Query: 274 EYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVH-LRKHTGEKFAC--DY 330 EYC K+F ++ H+R HT E Y C QC Y+S K L H ++KH+ C D Sbjct: 733 EYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDG 792 Query: 331 CSFTCLSK----GHLKVHIERVHKKIKQHCR 357 C ++ K HLKVH V K K+ R Sbjct: 793 CDYSTPDKYKLQAHLKVHTALVSSKPKRQPR 823 Score = 64.3 bits (155), Expect = 7e-10 Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 21/192 (10%) Query: 906 VKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQ 965 +K F C C + K +L+AH+ H+ EK + C C K L H HT G++ Sbjct: 256 LKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHT--GEK 313 Query: 966 FKCTVCDYTAAQKPQLLRHMEQ-HVSFKPFRCAHCHYSCNISGSLKRHYNRKH-PNEEYA 1023 F C C +T K L H+E+ H K C C + +L +H H P ++ Sbjct: 314 FACDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKKV 372 Query: 1024 NVGTGELAAEVLIQQGGLK----CPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPKWET 1079 EL ++ ++G + C +C + + + +RH+ + GD KW Sbjct: 373 KEALDELC--LMTREGKRQLLYDCHICERKFKNELDRDRHML---------VHGD-KWPF 420 Query: 1080 ATEAPEEPSTQY 1091 A E +T+Y Sbjct: 421 ACELCGHGATKY 432 Score = 37.7 bits (86), Expect = 0.069 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 6/91 (6%) Query: 910 KCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCT 969 +C C + + H+ H+ E + C C +K LK H ++ KC Sbjct: 731 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRH-VIQKHSNILLKCP 789 Query: 970 V--CDYTAAQKPQLLRHMEQH---VSFKPFR 995 CDY+ K +L H++ H VS KP R Sbjct: 790 TDGCDYSTPDKYKLQAHLKVHTALVSSKPKR 820 Score = 37.7 bits (86), Expect = 0.069 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 21/97 (21%) Query: 967 KCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVG 1026 +C C + H+ H + C+ CHYS LKRH +KH N Sbjct: 731 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSN------- 783 Query: 1027 TGELAAEVLIQQGGLKCPV--CSFVYGTKWEFNRHLK 1061 +L LKCP C + K++ HLK Sbjct: 784 -------IL-----LKCPTDGCDYSTPDKYKLQAHLK 808 Score = 37.0 bits (84), Expect = 0.12 Identities = 35/161 (21%), Positives = 59/161 (36%), Gaps = 38/161 (23%) Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 D C + + + A +KV +L K+ + +CE+ I Sbjct: 688 DSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLCER-----------------------IR 724 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 +V G ++C YC F H+ H + CS C Y++ +K+ Sbjct: 725 KVYGD------------LECEYCGKLFWYQ-VHFDMHVRTHTREHLYYCSQCHYSSITKN 771 Query: 923 NLKAHMNRHSTEKTHLC--DMCGKKFKSKGTLKSHKLLHTA 961 LK H+ + + C D C K L++H +HTA Sbjct: 772 CLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTA 812 Score = 34.7 bits (78), Expect = 0.58 Identities = 34/126 (26%), Positives = 49/126 (38%), Gaps = 24/126 (19%) Query: 889 FMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKS 948 FMK + LQ+ K SLCE + +L+ C+ CGK F Sbjct: 703 FMKVLNSLQK--------KQMNTSLCERIRKVYGDLE-------------CEYCGKLFWY 741 Query: 949 KGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCA--HCHYSCNIS 1006 + H HT + + C+ C Y++ K L RH+ Q S +C C YS Sbjct: 742 QVHFDMHVRTHTREHLYY-CSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDK 800 Query: 1007 GSLKRH 1012 L+ H Sbjct: 801 YKLQAH 806 >gi|156627573 zinc finger protein 836 [Homo sapiens] Length = 936 Score = 145 bits (365), Expect = 3e-34 Identities = 106/403 (26%), Positives = 167/403 (41%), Gaps = 39/403 (9%) Query: 696 THQPDSCKAAPE--HRSGITAFMKVLNSLQKKQMNTSLCERIRKVYGDL----------- 742 T +P C + HR + +++++ + K +C +I + DL Sbjct: 242 TEKPYKCNECGKAFHRGSLLTIHQIVHT-RGKPYQCGVCGKIFRQNSDLVNHRRSHTGEK 300 Query: 743 --ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKC 800 +C CGK F + +H R HT E Y C++C + +CL H I +C Sbjct: 301 PYKCNECGKSFSQSYNLAIHQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIHTGEKPYQC 360 Query: 801 PTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSM 858 D C L H ++HT ++ Y C +C KSFS+ + +H + + + Sbjct: 361 --DICGKVFRQNSNLVNHQRIHTG--EKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKC 416 Query: 859 STISEVLGRRVQLKGL----IGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLC 914 + R L G++ C CD F + S L RH +H G KP+KC+ C Sbjct: 417 DECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQR-SQLARHQRSHTGEKPYKCNEC 475 Query: 915 EYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYT 974 S+L H H+ EK + CD CGK FK L HK++HT + K+++C C Sbjct: 476 GKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTRE-KRYQCGECGKV 534 Query: 975 AAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE----------YAN 1024 ++ L+RH+ H +P++C C N SG+L H R H E+ + N Sbjct: 535 FSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIH-KRIHTGEKPFQCNECGTVFRN 593 Query: 1025 VGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 + Q KC VC V+ + H + G K Sbjct: 594 YSCLARHLRIHTGQKPYKCNVCGKVFNDSGNLSNHKRIHTGEK 636 Score = 132 bits (333), Expect = 2e-30 Identities = 93/327 (28%), Positives = 135/327 (41%), Gaps = 43/327 (13%) Query: 695 ITHQPDSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQ 754 I +P CK G +V +SL +N + K Y +C CGK F Sbjct: 213 IREKPYMCK-------GCGKAFRVSSSL----INHQMVHTTEKPY---KCNECGKAFHRG 258 Query: 755 VHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYK 814 +H HTR Y C C + L H KC + C S Y Sbjct: 259 SLLTIHQIVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKC--NECGKSFSQSYN 316 Query: 815 LQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGL 874 L H ++HT ++ Y C C K+F + + +H + Sbjct: 317 LAIHQRIHTG--EKPYKCNECGKTFKQGSCLTTHQIIH---------------------- 352 Query: 875 IGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTE 934 G++ +C C F +N S+L H H G KP+KC++C + SNL H HS Sbjct: 353 TGEKPYQCDICGKVFRQN-SNLVNHQRIHTGEKPYKCNICGKSFSQSSNLATHQTVHSGN 411 Query: 935 KTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPF 994 K + CD CGK FK +L +H+++HT + K + C VCD +Q+ QL RH H KP+ Sbjct: 412 KPYKCDECGKTFKRSSSLTTHQIIHTGE-KPYTCDVCDKVFSQRSQLARHQRSHTGEKPY 470 Query: 995 RCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +C C + + L H R H E+ Sbjct: 471 KCNECGKVFSQTSHLVGH-RRIHTGEK 496 Score = 124 bits (312), Expect = 4e-28 Identities = 77/276 (27%), Positives = 123/276 (44%), Gaps = 12/276 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F + H R HT E + C++C +CL RH KC Sbjct: 611 KCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARHRKIHTGEKPYKC-- 668 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMS--- 859 + C + + L HL +HT ++ Y+C +F + + + + E Sbjct: 669 NDCGKAYTQRSSLTKHLIIHTG--EKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHKCSH 726 Query: 860 ---TISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 T S + G + G+ KC C F + S+L RH H G KP+KC+ C Sbjct: 727 CGRTFSHITGLTYHQRRHTGEMPYKCIECGQVF-NSTSNLARHRRIHTGEKPYKCNECGK 785 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 R +S L H + H+ EK ++C+ CGK F+ + L +H+ +HT D K +KC C Sbjct: 786 VFRHQSTLARHRSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGD-KPYKCNECGKAFI 844 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 ++ +L+ H H KP++C C + L +H Sbjct: 845 ERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKH 880 Score = 118 bits (295), Expect = 4e-26 Identities = 75/254 (29%), Positives = 109/254 (42%), Gaps = 28/254 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F H H R HT E Y C +C + + L RH I +C Sbjct: 471 KCNECGKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGE 530 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 G +S + L HL++HT ++ Y C VC K F+ + H + + Sbjct: 531 CGKVFS--ENSCLVRHLRIHTG--EQPYKCNVCGKVFNYSGNLSIHKRIH---------- 576 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 G++ +C C F +N S L RH+ H G KP+KC++C Sbjct: 577 ------------TGEKPFQCNECGTVF-RNYSCLARHLRIHTGQKPYKCNVCGKVFNDSG 623 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 NL H H+ EK C+ CGK F L H+ +HT + K +KC C Q+ L Sbjct: 624 NLSNHKRIHTGEKPFQCNECGKVFSYYSCLARHRKIHTGE-KPYKCNDCGKAYTQRSSLT 682 Query: 983 RHMEQHVSFKPFRC 996 +H+ H KP+ C Sbjct: 683 KHLIIHTGEKPYNC 696 Score = 117 bits (294), Expect = 5e-26 Identities = 96/359 (26%), Positives = 132/359 (36%), Gaps = 73/359 (20%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C+ CGK+F + H R HT E Y C+ C S + L H N KC Sbjct: 359 QCDICGKVFRQNSNLVNHQRIHTGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKC-- 416 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH---------IKTNH 853 D C + L H +HT ++ Y+C VC+K FS+ + H K N Sbjct: 417 DECGKTFKRSSSLTTHQIIHTG--EKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNE 474 Query: 854 PEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNG-------------------- 893 S S ++G R + G++ KC C F + Sbjct: 475 CGKVFSQTSHLVGHR---RIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGEC 531 Query: 894 -------SDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKF 946 S L RH+ H G +P+KC++C NL H H+ EK C+ CG F Sbjct: 532 GKVFSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGEKPFQCNECGTVF 591 Query: 947 KSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHC-----HY 1001 ++ L H +HT K +KC VC L H H KPF+C C +Y Sbjct: 592 RNYSCLARHLRIHTGQ-KPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYY 650 Query: 1002 SCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHL 1060 SC L RH + TGE KC C Y + +HL Sbjct: 651 SC-----LARH----------RKIHTGEKP---------YKCNDCGKAYTQRSSLTKHL 685 Score = 113 bits (282), Expect = 1e-24 Identities = 91/341 (26%), Positives = 142/341 (41%), Gaps = 25/341 (7%) Query: 700 DSCKAAPEHRSGITAFMKVLNSLQKKQM----------NTSLCERIRKVYGD--LECEYC 747 D C A + S +T K++++ +K+ N+ L +R G+ +C C Sbjct: 501 DKCGKAFKQGSLLTRH-KIIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQPYKCNVC 559 Query: 748 GKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDY 807 GK+F Y + +H R HT E + C++C +CL RH+ KC G + Sbjct: 560 GKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCLARHLRIHTGQKPYKCNVCGKVF 619 Query: 808 STPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMSTISEVL 865 + D L H ++HT ++ + C C K FS + H I T + + Sbjct: 620 N--DSGNLSNHKRIHTG--EKPFQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAY 675 Query: 866 GRRVQL-KGLI---GKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSK 921 +R L K LI G++ C F+++ S L R+ G KP KCS C Sbjct: 676 TQRSSLTKHLIIHTGEKPYNCNEFGGAFIQS-SKLARYHRNPTGEKPHKCSHCGRTFSHI 734 Query: 922 SNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQL 981 + L H RH+ E + C CG+ F S L H+ +HT + K +KC C + L Sbjct: 735 TGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGE-KPYKCNECGKVFRHQSTL 793 Query: 982 LRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEY 1022 RH H KP+ C C + + L H ++ Y Sbjct: 794 ARHRSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPY 834 Score = 106 bits (264), Expect = 2e-22 Identities = 69/217 (31%), Positives = 97/217 (44%), Gaps = 28/217 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K +TC+ C+KVF + L H R HT EKPYKC +C + ++L H R HTGEK + Sbjct: 440 KPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPYK 499 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 CD C +G L + +H + K++ C C K +S+ L++H+R Q Sbjct: 500 CDKCG-KAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQP----- 553 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 Y C++C + F + H +H + PF C CG Y Sbjct: 554 -----------------YKCNVCGKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSC 596 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 L H+R H Y C VC K F S L H K +H Sbjct: 597 LARHLRIHTGQKPYKCNVCGKVFNDSGNLSNH-KRIH 632 Score = 98.2 bits (243), Expect = 4e-20 Identities = 64/215 (29%), Positives = 90/215 (41%), Gaps = 27/215 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ K + C C K+F+ L H R HT EKPYKC +C + + NL +H R HTGEK Sbjct: 269 TRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTGEK 328 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 + C+ C T L H + +H K + C C K + NL+ H R Sbjct: 329 PYKCNECGKTFKQGSCLTTH-QIIHTGEKPYQCDICGKVFRQNSNLVNHQR--------- 378 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 G++ Y C+IC + F + H VH P+ C+ CG + Sbjct: 379 -----------IHTGEKP--YKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKR 425 Query: 444 YQALELH--VRKHPFVYVCAVCRKKFVSSIRLRTH 476 +L H + Y C VC K F +L H Sbjct: 426 SSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARH 460 Score = 95.1 bits (235), Expect = 4e-19 Identities = 65/226 (28%), Positives = 90/226 (39%), Gaps = 32/226 (14%) Query: 262 RLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKH 321 R T K + C C K F ++L H RIHT EKPYKC +C + L H H Sbjct: 293 RRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIH 352 Query: 322 TGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAH 377 TGEK + CD C +L H +R+H K + C C K +S NL H + + Sbjct: 353 TGEKPYQCDICGKVFRQNSNLVNH-QRIHTGEKPYKCNICGKSFSQSSNLATHQTVHSGN 411 Query: 378 DPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 P Y C C + FK H ++H + P+ C++C Sbjct: 412 KP------------------------YKCDECGKTFKRSSSLTTHQIIHTGEKPYTCDVC 447 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 ++ L H R H Y C C K F + L H + +H Sbjct: 448 DKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGH-RRIH 492 Score = 95.1 bits (235), Expect = 4e-19 Identities = 73/259 (28%), Positives = 107/259 (41%), Gaps = 50/259 (19%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ K + C C KVF L HLRIHT E+PYKC C NL++H R HTGEK Sbjct: 521 TREKRYQCGECGKVFSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGEK 580 Query: 326 -FACDYC-----SFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH--IRDAH 377 F C+ C +++CL++ HL++H + K C C K ++D NL H I Sbjct: 581 PFQCNECGTVFRNYSCLAR-HLRIHTGQKPYK----CNVCGKVFNDSGNLSNHKRIHTGE 635 Query: 378 DP-QDKKVKEALDELCLMTREGK---RQLLYDCHICERKFKNELDRDRHMLVH------- 426 P Q + + + R K + Y C+ C + + +H+++H Sbjct: 636 KPFQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRSSLTKHLIIHTGEKPYN 695 Query: 427 ----------------------GDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAV 462 G+K P C CG + L H R+H Y C Sbjct: 696 CNEFGGAFIQSSKLARYHRNPTGEK-PHKCSHCGRTFSHITGLTYHQRRHTGEMPYKCIE 754 Query: 463 CRKKFVSSIRLRTHIKEVH 481 C + F S+ L H + +H Sbjct: 755 CGQVFNSTSNLARH-RRIH 772 Score = 94.0 bits (232), Expect = 8e-19 Identities = 71/231 (30%), Positives = 95/231 (41%), Gaps = 22/231 (9%) Query: 265 PTQL-------KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVH 317 PTQL K + C+ C K F+ SL H +HT EKPYKC +C A + L +H Sbjct: 205 PTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIH 264 Query: 318 LRKHT-GEKFACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRD 375 HT G+ + C C L H R H K + C C K +S NL H R Sbjct: 265 QIVHTRGKPYQCGVCGKIFRQNSDLVNH-RRSHTGEKPYKCNECGKSFSQSYNLAIHQRI 323 Query: 376 AHDPQDKKVKEA----LDELCLMTRE----GKRQLLYDCHICERKFKNELDRDRHMLVHG 427 + K E CL T + G++ Y C IC + F+ + H +H Sbjct: 324 HTGEKPYKCNECGKTFKQGSCLTTHQIIHTGEKP--YQCDICGKVFRQNSNLVNHQRIHT 381 Query: 428 DKWPFACELCGHGATKYQALELHVRKHP--FVYVCAVCRKKFVSSIRLRTH 476 + P+ C +CG ++ L H H Y C C K F S L TH Sbjct: 382 GEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTH 432 Score = 86.7 bits (213), Expect = 1e-16 Identities = 65/228 (28%), Positives = 92/228 (40%), Gaps = 27/228 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C +CG+ F + H R HT E Y C +C + + L RH KC Sbjct: 723 KCSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKC-- 780 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + C + L H +HT ++ Y C C K+F ++ +H K + Sbjct: 781 NECGKVFRHQSTLARHRSIHTG--EKPYVCNECGKAFRVRSILVNHQKMH---------- 828 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 G + KC C F++ S L H H G KP+KC C A S Sbjct: 829 ------------TGDKPYKCNECGKAFIER-SKLVYHQRNHTGEKPYKCIECGKAFGRFS 875 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTV 970 L H HS EK + C+ CGK F S+ L H+ HTA+ + K V Sbjct: 876 CLNKHQMIHSGEKPYKCNECGKSFISRSGLTKHQTKHTAESLKTKFNV 923 Score = 79.3 bits (194), Expect = 2e-14 Identities = 57/211 (27%), Positives = 83/211 (39%), Gaps = 25/211 (11%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K + + SL HL IHT EKPY C + A + L + R TGEK Sbjct: 664 KPYKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHK 723 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEA 387 C +C T L H R ++ C C + ++ NL +H R Sbjct: 724 CSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRR------------- 770 Query: 388 LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQAL 447 G++ Y C+ C + F+++ RH +H + P+ C CG L Sbjct: 771 -------IHTGEKP--YKCNECGKVFRHQSTLARHRSIHTGEKPYVCNECGKAFRVRSIL 821 Query: 448 ELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 H + H Y C C K F+ +L H Sbjct: 822 VNHQKMHTGDKPYKCNECGKAFIERSKLVYH 852 Score = 79.0 bits (193), Expect = 3e-14 Identities = 55/198 (27%), Positives = 77/198 (38%), Gaps = 9/198 (4%) Query: 265 PTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGE 324 PT K C +C + F L H R HT E PYKC +C +NL H R HTGE Sbjct: 716 PTGEKPHKCSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGE 775 Query: 325 K-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDK 382 K + C+ C + L H +H K + C C K + L+ H + + Sbjct: 776 KPYKCNECGKVFRHQSTLARH-RSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPY 834 Query: 383 KVKEA------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACEL 436 K E +L R + Y C C + F ++H ++H + P+ C Sbjct: 835 KCNECGKAFIERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNE 894 Query: 437 CGHGATKYQALELHVRKH 454 CG L H KH Sbjct: 895 CGKSFISRSGLTKHQTKH 912 Score = 78.2 bits (191), Expect = 5e-14 Identities = 43/119 (36%), Positives = 59/119 (49%), Gaps = 2/119 (1%) Query: 903 HEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTAD 962 H KP+ C C A R S+L H H+TEK + C+ CGK F L H+++HT Sbjct: 212 HIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTR- 270 Query: 963 GKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 GK ++C VC Q L+ H H KP++C C S + S +L H R H E+ Sbjct: 271 GKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIH-QRIHTGEK 328 Score = 70.5 bits (171), Expect = 1e-11 Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 14/124 (11%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ + L H ++HT +KPYKC +C A ++ L H R HTGEK + Sbjct: 804 KPYVCNECGKAFRVRSILVNHQKMHTGDKPYKCNECGKAFIERSKLVYHQRNHTGEKPYK 863 Query: 328 CDYCS-----FTCLSKGHLKVHI-ERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQD 381 C C F+CL+K H +H E+ +K C C K + L KH + H + Sbjct: 864 CIECGKAFGRFSCLNK-HQMIHSGEKPYK-----CNECGKSFISRSGLTKH-QTKHTAES 916 Query: 382 KKVK 385 K K Sbjct: 917 LKTK 920 >gi|239747149 PREDICTED: hypothetical protein XP_002343926 isoform 2 [Homo sapiens] Length = 738 Score = 143 bits (361), Expect = 9e-34 Identities = 106/343 (30%), Positives = 147/343 (42%), Gaps = 23/343 (6%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + F H RTHT E Y CSQC + K+ L H +C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMSTI 861 G +S K L +H + HT ++ Y C C ++FSE + +H I T Sbjct: 297 GKAFSR--KSHLISHWRTHTG--EKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + R+ QL + G + C C F + S+L RH H G KP++CS C A Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK-SELIRHQTIHTGEKPYECSECRKA 411 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 R +S+L H H+ EK H C CGK F K L SH++ HT + K F C+ C ++ Sbjct: 412 FRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGE-KPFICSKCGKAFSR 470 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE---YANVGTGELAAEV 1034 K QL+RH H KP+ C+ C + + SL H R H E+ + G Sbjct: 471 KSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNH-QRIHTGEKPYVCSECGKAFCQKSH 529 Query: 1035 LIQ-------QGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 LI + +C C +G K H + G K E Sbjct: 530 LISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Score = 138 bits (347), Expect = 4e-32 Identities = 87/284 (30%), Positives = 134/284 (47%), Gaps = 13/284 (4%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H THT E + CS+C + K+ L RH +C Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE--VSMSTI 861 G +S +K L H ++HT ++ Y C C K+F + + SH +T+ E S Sbjct: 493 GKAFS--EKLSLTNHQRIHTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + G + L + G++ +C C+ F + S L H H G KP++CSLC A Sbjct: 549 GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK-SQLNTHQRIHTGEKPYECSLCRKA 607 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 KS L H+ H+ EK + C+ C K F+ K +L +H+ +HT + K F+C+ C ++ Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE-KPFECSECGKAFSR 666 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 K L+ H H KP+ C+ C + + L H R H E+ Sbjct: 667 KSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH-QRIHTGEK 709 Score = 134 bits (336), Expect = 7e-31 Identities = 104/344 (30%), Positives = 140/344 (40%), Gaps = 23/344 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H H RTHT E Y C++C + K+ L H +C Sbjct: 292 ECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 G +S K +L H + HT + + C C K+F E + H I T S Sbjct: 352 CGKAFSR--KSQLVTHHRTHTG--TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSE 407 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R L + G++ C C F + S L H H G KPF CS C Sbjct: 408 CRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQK-SHLISHQMTHTGEKPFICSKCGK 466 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A KS L H H+ EK + C CGK F K +L +H+ +HT + K + C+ C Sbjct: 467 AFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGE-KPYVCSECGKAFC 525 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE--------EYANVGTG 1028 QK L+ H H KP+ C+ C + SL H R H E E A Sbjct: 526 QKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH-QRTHTGEKPYECRDCEKAFSQKS 584 Query: 1029 ELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 +L I G +C +C + K E RHL+ G K E Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYE 628 Score = 133 bits (335), Expect = 9e-31 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 32/272 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F ++ H R HT E Y CS+C + C K H+I + P Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF----CQKSHLISHQRTHTGEKPY 543 Query: 803 D--GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMST 860 + C + +K L H + HT ++ Y C CEK+FS+ + +H + + Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTG--EKPYECRDCEKAFSQKSQLNTHQRIH-------- 593 Query: 861 ISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRS 920 G++ +C C F + S+L RH+ H G KP++C+ C A R Sbjct: 594 --------------TGEKPYECSLCRKAFFEK-SELIRHLRTHTGEKPYECNECRKAFRE 638 Query: 921 KSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQ 980 KS+L H H+ EK C CGK F K L H+ HT + K + C+ C +QK Q Sbjct: 639 KSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGE-KPYGCSECRKAFSQKSQ 697 Query: 981 LLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L+ H H KP+RC C + + L H Sbjct: 698 LVNHQRIHTGEKPYRCIECGKAFSQKSQLINH 729 Score = 127 bits (319), Expect = 7e-29 Identities = 90/295 (30%), Positives = 131/295 (44%), Gaps = 13/295 (4%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H RTHT + CS C + K+ L RH Sbjct: 338 QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH 397 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +C C + ++ L H + HT ++ + C C K+FS+ + SH T+ Sbjct: 398 TGEKPYEC--SECRKAFRERSSLINHQRTHTG--EKPHGCIQCGKAFSQKSHLISHQMTH 453 Query: 853 HPEVSM--STISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGV 906 E S + R+ QL + G++ +C C F + S L H H G Sbjct: 454 TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS-LTNHQRIHTGE 512 Query: 907 KPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQF 966 KP+ CS C A KS+L +H H+ EK + C CGK F K +L +H+ HT + K + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGE-KPY 571 Query: 967 KCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +C C+ +QK QL H H KP+ C+ C + L RH R H E+ Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHL-RTHTGEK 625 Score = 122 bits (306), Expect = 2e-27 Identities = 75/245 (30%), Positives = 109/245 (44%), Gaps = 28/245 (11%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H RTHT E Y CS+C + K+ L H +C Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRD- 575 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C+ + K +L H ++HT ++ Y C +C K+F E + H++T+ Sbjct: 576 -CEKAFSQKSQLNTHQRIHTG--EKPYECSLCRKAFFEKSELIRHLRTH----------- 621 Query: 864 VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSN 923 G++ +C C F + S L H H G KPF+CS C A KS+ Sbjct: 622 -----------TGEKPYECNECRKAFREKSS-LINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 924 LKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLR 983 L H H+ EK + C C K F K L +H+ +HT + K ++C C +QK QL+ Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGE-KPYRCIECGKAFSQKSQLIN 728 Query: 984 HMEQH 988 H H Sbjct: 729 HQRTH 733 Score = 115 bits (288), Expect = 3e-25 Identities = 86/318 (27%), Positives = 125/318 (39%), Gaps = 37/318 (11%) Query: 762 RTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKV 821 R E LY CS+C K L +H + +I C C + P K + H + Sbjct: 199 RNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGC--GNCGKTFPQKSQFITHHRT 256 Query: 822 HTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMK 881 HT ++ Y+C C K+FS+ + SH +T+ G++ + Sbjct: 257 HTG--EKPYNCSQCGKAFSQKSQLTSHQRTH----------------------TGEKPYE 292 Query: 882 CPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDM 941 C C F + S L H H G KP+ C+ C A KSNL H H+ EK C Sbjct: 293 CGECGKAFSRK-SHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 942 CGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHY 1001 CGK F K L +H HT K F C+ C +K +L+RH H KP+ C+ C Sbjct: 352 CGKAFSRKSQLVTHHRTHTGT-KPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRK 410 Query: 1002 SCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG--GLKCPVCSFVYGT 1052 + SL H + + + G+ L + + G C C + Sbjct: 411 AFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSR 470 Query: 1053 KWEFNRHLKNKHGLKVVE 1070 K + RH + G K E Sbjct: 471 KSQLVRHQRTHTGEKPYE 488 Score = 110 bits (275), Expect = 8e-24 Identities = 67/212 (31%), Positives = 95/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A K++L H R HTGEK + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R+H K + C C+K + + LI+H+R Sbjct: 573 CRDCEKAFSQKSQLNTH-QRIHTGEKPYECSLCRKAFFEKSELIRHLR------------ 619 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y+C+ C + F+ + H +H + PF C CG ++ Sbjct: 620 --------THTGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 447 LELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ CRK F +L H Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH 701 Score = 105 bits (263), Expect = 2e-22 Identities = 70/221 (31%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 260 SSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLR 319 S ++ T K F C C K F K L H R HT EKPY+C +C A + K +L H R Sbjct: 448 SHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQR 507 Query: 320 KHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAH 377 HTGEK + C C K HL H +R H K + C C K + + +L H R Sbjct: 508 IHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECGKAFGEKSSLATHQR--- 563 Query: 378 DPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 T G++ Y+C CE+ F + + H +H + P+ C LC Sbjct: 564 -----------------THTGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + L H+R H Y C CRK F L H Sbjct: 605 RKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINH 645 Score = 97.8 bits (242), Expect = 6e-20 Identities = 60/214 (28%), Positives = 94/214 (43%), Gaps = 8/214 (3%) Query: 805 CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSM--STIS 862 CD K Q + L ++ Y C C K FS+ + H + +++ Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241 Query: 863 EVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYAT 918 + ++ Q + G++ C C F + S L H H G KP++C C A Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQK-SQLTSHQRTHTGEKPYECGECGKAF 300 Query: 919 RSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQK 978 KS+L +H H+ EK + C+ CG+ F K L +H+ +HT + K F+C C ++K Sbjct: 301 SRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGE-KPFECRECGKAFSRK 359 Query: 979 PQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 QL+ H H KPF C+ C + L RH Sbjct: 360 SQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 97.4 bits (241), Expect = 7e-20 Identities = 70/227 (30%), Positives = 96/227 (42%), Gaps = 19/227 (8%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A + K++L H R HTGEK + Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQD----- 381 C+ C K +L H +R+H K CR C K +S L+ H R + Sbjct: 321 CNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSD 379 Query: 382 -KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 +K EL + Y+C C + F+ H H + P C CG Sbjct: 380 CRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439 Query: 441 ATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRL----RTHIKE 479 ++ L H H PF +C+ C K F +L RTH E Sbjct: 440 FSQKSHLISHQMTHTGEKPF--ICSKCGKAFSRKSQLVRHQRTHTGE 484 Score = 97.1 bits (240), Expect = 1e-19 Identities = 68/215 (31%), Positives = 87/215 (40%), Gaps = 27/215 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K F C C K F K L H IHT EKPY+C +C A +++L H R HTGEK Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 C C K HL H + H K C C K +S L++H R Sbjct: 430 PHGCIQCGKAFSQKSHLISH-QMTHTGEKPFICSKCGKAFSRKSQLVRHQR--------- 479 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 T G++ Y+C C + F +L H +H + P+ C CG + Sbjct: 480 -----------THTGEKP--YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQ 526 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ C K F L TH Sbjct: 527 KSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561 Score = 95.9 bits (237), Expect = 2e-19 Identities = 62/194 (31%), Positives = 82/194 (42%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K SL H R HT EKPY+C C A + K+ LN H R HTGEK + Sbjct: 541 KPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----Q 380 C C K L H+ R H K + C C+K + + +LI H I P + Sbjct: 601 CSLCRKAFFEKSELIRHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 K L R + Y C C + F + H +H + P+ C CG Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719 Query: 441 ATKYQALELHVRKH 454 ++ L H R H Sbjct: 720 FSQKSQLINHQRTH 733 Score = 95.5 bits (236), Expect = 3e-19 Identities = 66/220 (30%), Positives = 92/220 (41%), Gaps = 11/220 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ + SL H R HT EKP+ C QC A + K++L H HTGEK F Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R H K + C C K +S+ +L H R + E Sbjct: 461 CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE 519 Query: 387 ALDELCLMT------REGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 C + R + Y+C C + F + H H + P+ C C Sbjct: 520 CGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKA 579 Query: 441 ATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTHIK 478 ++ L H R H Y C++CRK F L H++ Sbjct: 580 FSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLR 619 Score = 94.7 bits (234), Expect = 5e-19 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 21/221 (9%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 F C C K F K H R HT EKPY C QC A + K+ L H R HTGEK + C Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG 294 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEAL 388 C K HL H R H K + C C + +S+ NLI H R + + +E Sbjct: 295 ECGKAFSRKSHLISH-WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE-- 351 Query: 389 DELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 C K QL+ + C C + F + + RH +H + P+ C C Sbjct: 352 ---CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + +L H R H + C C K F L +H Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH 449 Score = 84.7 bits (208), Expect = 5e-16 Identities = 64/220 (29%), Positives = 86/220 (39%), Gaps = 30/220 (13%) Query: 261 SRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRK 320 +RLG K++ C C K F K SL H H + + C C K+ H R Sbjct: 200 NRLGE---KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRT 256 Query: 321 HTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHD 378 HTGEK + C C K L H +R H K + C C K +S +LI H R Sbjct: 257 HTGEKPYNCSQCGKAFSQKSQLTSH-QRTHTGEKPYECGECGKAFSRKSHLISHWR---- 311 Query: 379 PQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG 438 T G++ Y C+ C R F + + H +H + PF C CG Sbjct: 312 ----------------THTGEKP--YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECG 353 Query: 439 HGATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 ++ L H R H + C+ CRK F L H Sbjct: 354 KAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 79.0 bits (193), Expect = 3e-14 Identities = 58/200 (29%), Positives = 82/200 (41%), Gaps = 11/200 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H RTHT E Y C C + K+ L H +C Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 C + +K +L HL+ HT ++ Y C C K+F E + +H I T S Sbjct: 604 --CRKAFFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R+ L + G++ C C F + S L H H G KP++C C Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQK-SQLVNHQRIHTGEKPYRCIECGK 718 Query: 917 ATRSKSNLKAHMNRHSTEKT 936 A KS L H H+ +K+ Sbjct: 719 AFSQKSQLINHQRTHTVKKS 738 Score = 55.5 bits (132), Expect = 3e-07 Identities = 65/229 (28%), Positives = 87/229 (37%), Gaps = 47/229 (20%) Query: 99 EDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELE 158 E S LA + EC C + FS QL H I GE E L Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI-------HTGEKPYECSL--- 603 Query: 159 KKCKEDDREKAS--KRPRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKI 216 C++ EK+ + R+ EK + + E R+ K +I+ H+ I K Sbjct: 604 --CRKAFFEKSELIRHLRTHTGEKPYECN--ECRKAFREKSSLIN-----HQRIHTGEK- 653 Query: 217 VPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYC 276 P E E G S + L+P +Q + PY C C Sbjct: 654 -PFECS--ECGKAFSR--KSHLIP---HQRTHTGEKPYG-----------------CSEC 688 Query: 277 NKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K F K L H RIHT EKPY+C +C A + K+ L H R HT +K Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737 Score = 48.1 bits (113), Expect = 5e-05 Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 14/191 (7%) Query: 297 KPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH 355 K Y C + S K+ + ++ R GEK + C C K L H R + I Sbjct: 178 KYYDCDKYK-ESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236 Query: 356 CRFCKKKYSDVKNLIKHIR------DAHDPQDKKVKEALDELCLMTREGKRQLLYDCHIC 409 C C K + I H R + Q K +L R + Y+C C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 410 ERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH----PFVYVCAVCRK 465 + F + H H + P+ C CG ++ L H R H PF C C K Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPF--ECRECGK 354 Query: 466 KFVSSIRLRTH 476 F +L TH Sbjct: 355 AFSRKSQLVTH 365 Score = 46.6 bits (109), Expect = 1e-04 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 32/120 (26%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H H RTHT E Y CS+C + K+ Sbjct: 646 QRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKS--------- 696 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +L H ++HT ++ Y C C K+FS+ + +H +T+ Sbjct: 697 ---------------------QLVNHQRIHTG--EKPYRCIECGKAFSQKSQLINHQRTH 733 Score = 37.4 bits (85), Expect = 0.090 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 6/121 (4%) Query: 358 FCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNEL 417 F K D +K+ +D K ++ + R + LY+C C ++F + Sbjct: 165 FLHSKPEDTDTWLKY----YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKP 220 Query: 418 DRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRT 475 +H H F C CG + H R H Y C+ C K F +L + Sbjct: 221 SLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTS 280 Query: 476 H 476 H Sbjct: 281 H 281 >gi|239747147 PREDICTED: hypothetical protein XP_002343925 isoform 1 [Homo sapiens] Length = 738 Score = 143 bits (361), Expect = 9e-34 Identities = 106/343 (30%), Positives = 147/343 (42%), Gaps = 23/343 (6%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + F H RTHT E Y CSQC + K+ L H +C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMSTI 861 G +S K L +H + HT ++ Y C C ++FSE + +H I T Sbjct: 297 GKAFSR--KSHLISHWRTHTG--EKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + R+ QL + G + C C F + S+L RH H G KP++CS C A Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK-SELIRHQTIHTGEKPYECSECRKA 411 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 R +S+L H H+ EK H C CGK F K L SH++ HT + K F C+ C ++ Sbjct: 412 FRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGE-KPFICSKCGKAFSR 470 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE---YANVGTGELAAEV 1034 K QL+RH H KP+ C+ C + + SL H R H E+ + G Sbjct: 471 KSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNH-QRIHTGEKPYVCSECGKAFCQKSH 529 Query: 1035 LIQ-------QGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 LI + +C C +G K H + G K E Sbjct: 530 LISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Score = 138 bits (347), Expect = 4e-32 Identities = 87/284 (30%), Positives = 134/284 (47%), Gaps = 13/284 (4%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H THT E + CS+C + K+ L RH +C Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE--VSMSTI 861 G +S +K L H ++HT ++ Y C C K+F + + SH +T+ E S Sbjct: 493 GKAFS--EKLSLTNHQRIHTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + G + L + G++ +C C+ F + S L H H G KP++CSLC A Sbjct: 549 GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK-SQLNTHQRIHTGEKPYECSLCRKA 607 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 KS L H+ H+ EK + C+ C K F+ K +L +H+ +HT + K F+C+ C ++ Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE-KPFECSECGKAFSR 666 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 K L+ H H KP+ C+ C + + L H R H E+ Sbjct: 667 KSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH-QRIHTGEK 709 Score = 134 bits (336), Expect = 7e-31 Identities = 104/344 (30%), Positives = 140/344 (40%), Gaps = 23/344 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H H RTHT E Y C++C + K+ L H +C Sbjct: 292 ECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 G +S K +L H + HT + + C C K+F E + H I T S Sbjct: 352 CGKAFSR--KSQLVTHHRTHTG--TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSE 407 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R L + G++ C C F + S L H H G KPF CS C Sbjct: 408 CRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQK-SHLISHQMTHTGEKPFICSKCGK 466 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A KS L H H+ EK + C CGK F K +L +H+ +HT + K + C+ C Sbjct: 467 AFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGE-KPYVCSECGKAFC 525 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE--------EYANVGTG 1028 QK L+ H H KP+ C+ C + SL H R H E E A Sbjct: 526 QKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH-QRTHTGEKPYECRDCEKAFSQKS 584 Query: 1029 ELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 +L I G +C +C + K E RHL+ G K E Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYE 628 Score = 133 bits (335), Expect = 9e-31 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 32/272 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F ++ H R HT E Y CS+C + C K H+I + P Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF----CQKSHLISHQRTHTGEKPY 543 Query: 803 D--GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMST 860 + C + +K L H + HT ++ Y C CEK+FS+ + +H + + Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTG--EKPYECRDCEKAFSQKSQLNTHQRIH-------- 593 Query: 861 ISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRS 920 G++ +C C F + S+L RH+ H G KP++C+ C A R Sbjct: 594 --------------TGEKPYECSLCRKAFFEK-SELIRHLRTHTGEKPYECNECRKAFRE 638 Query: 921 KSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQ 980 KS+L H H+ EK C CGK F K L H+ HT + K + C+ C +QK Q Sbjct: 639 KSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGE-KPYGCSECRKAFSQKSQ 697 Query: 981 LLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L+ H H KP+RC C + + L H Sbjct: 698 LVNHQRIHTGEKPYRCIECGKAFSQKSQLINH 729 Score = 127 bits (319), Expect = 7e-29 Identities = 90/295 (30%), Positives = 131/295 (44%), Gaps = 13/295 (4%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H RTHT + CS C + K+ L RH Sbjct: 338 QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH 397 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +C C + ++ L H + HT ++ + C C K+FS+ + SH T+ Sbjct: 398 TGEKPYEC--SECRKAFRERSSLINHQRTHTG--EKPHGCIQCGKAFSQKSHLISHQMTH 453 Query: 853 HPEVSM--STISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGV 906 E S + R+ QL + G++ +C C F + S L H H G Sbjct: 454 TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS-LTNHQRIHTGE 512 Query: 907 KPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQF 966 KP+ CS C A KS+L +H H+ EK + C CGK F K +L +H+ HT + K + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGE-KPY 571 Query: 967 KCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +C C+ +QK QL H H KP+ C+ C + L RH R H E+ Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHL-RTHTGEK 625 Score = 122 bits (306), Expect = 2e-27 Identities = 75/245 (30%), Positives = 109/245 (44%), Gaps = 28/245 (11%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H RTHT E Y CS+C + K+ L H +C Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRD- 575 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C+ + K +L H ++HT ++ Y C +C K+F E + H++T+ Sbjct: 576 -CEKAFSQKSQLNTHQRIHTG--EKPYECSLCRKAFFEKSELIRHLRTH----------- 621 Query: 864 VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSN 923 G++ +C C F + S L H H G KPF+CS C A KS+ Sbjct: 622 -----------TGEKPYECNECRKAFREKSS-LINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 924 LKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLR 983 L H H+ EK + C C K F K L +H+ +HT + K ++C C +QK QL+ Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGE-KPYRCIECGKAFSQKSQLIN 728 Query: 984 HMEQH 988 H H Sbjct: 729 HQRTH 733 Score = 115 bits (288), Expect = 3e-25 Identities = 86/318 (27%), Positives = 125/318 (39%), Gaps = 37/318 (11%) Query: 762 RTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKV 821 R E LY CS+C K L +H + +I C C + P K + H + Sbjct: 199 RNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGC--GNCGKTFPQKSQFITHHRT 256 Query: 822 HTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMK 881 HT ++ Y+C C K+FS+ + SH +T+ G++ + Sbjct: 257 HTG--EKPYNCSQCGKAFSQKSQLTSHQRTH----------------------TGEKPYE 292 Query: 882 CPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDM 941 C C F + S L H H G KP+ C+ C A KSNL H H+ EK C Sbjct: 293 CGECGKAFSRK-SHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 942 CGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHY 1001 CGK F K L +H HT K F C+ C +K +L+RH H KP+ C+ C Sbjct: 352 CGKAFSRKSQLVTHHRTHTGT-KPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRK 410 Query: 1002 SCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG--GLKCPVCSFVYGT 1052 + SL H + + + G+ L + + G C C + Sbjct: 411 AFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSR 470 Query: 1053 KWEFNRHLKNKHGLKVVE 1070 K + RH + G K E Sbjct: 471 KSQLVRHQRTHTGEKPYE 488 Score = 110 bits (275), Expect = 8e-24 Identities = 67/212 (31%), Positives = 95/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A K++L H R HTGEK + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R+H K + C C+K + + LI+H+R Sbjct: 573 CRDCEKAFSQKSQLNTH-QRIHTGEKPYECSLCRKAFFEKSELIRHLR------------ 619 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y+C+ C + F+ + H +H + PF C CG ++ Sbjct: 620 --------THTGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 447 LELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ CRK F +L H Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH 701 Score = 105 bits (263), Expect = 2e-22 Identities = 70/221 (31%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 260 SSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLR 319 S ++ T K F C C K F K L H R HT EKPY+C +C A + K +L H R Sbjct: 448 SHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQR 507 Query: 320 KHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAH 377 HTGEK + C C K HL H +R H K + C C K + + +L H R Sbjct: 508 IHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECGKAFGEKSSLATHQR--- 563 Query: 378 DPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 T G++ Y+C CE+ F + + H +H + P+ C LC Sbjct: 564 -----------------THTGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + L H+R H Y C CRK F L H Sbjct: 605 RKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINH 645 Score = 97.8 bits (242), Expect = 6e-20 Identities = 60/214 (28%), Positives = 94/214 (43%), Gaps = 8/214 (3%) Query: 805 CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSM--STIS 862 CD K Q + L ++ Y C C K FS+ + H + +++ Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241 Query: 863 EVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYAT 918 + ++ Q + G++ C C F + S L H H G KP++C C A Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQK-SQLTSHQRTHTGEKPYECGECGKAF 300 Query: 919 RSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQK 978 KS+L +H H+ EK + C+ CG+ F K L +H+ +HT + K F+C C ++K Sbjct: 301 SRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGE-KPFECRECGKAFSRK 359 Query: 979 PQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 QL+ H H KPF C+ C + L RH Sbjct: 360 SQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 97.4 bits (241), Expect = 7e-20 Identities = 70/227 (30%), Positives = 96/227 (42%), Gaps = 19/227 (8%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A + K++L H R HTGEK + Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQD----- 381 C+ C K +L H +R+H K CR C K +S L+ H R + Sbjct: 321 CNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSD 379 Query: 382 -KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 +K EL + Y+C C + F+ H H + P C CG Sbjct: 380 CRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439 Query: 441 ATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRL----RTHIKE 479 ++ L H H PF +C+ C K F +L RTH E Sbjct: 440 FSQKSHLISHQMTHTGEKPF--ICSKCGKAFSRKSQLVRHQRTHTGE 484 Score = 97.1 bits (240), Expect = 1e-19 Identities = 68/215 (31%), Positives = 87/215 (40%), Gaps = 27/215 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K F C C K F K L H IHT EKPY+C +C A +++L H R HTGEK Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 C C K HL H + H K C C K +S L++H R Sbjct: 430 PHGCIQCGKAFSQKSHLISH-QMTHTGEKPFICSKCGKAFSRKSQLVRHQR--------- 479 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 T G++ Y+C C + F +L H +H + P+ C CG + Sbjct: 480 -----------THTGEKP--YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQ 526 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ C K F L TH Sbjct: 527 KSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561 Score = 95.9 bits (237), Expect = 2e-19 Identities = 62/194 (31%), Positives = 82/194 (42%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K SL H R HT EKPY+C C A + K+ LN H R HTGEK + Sbjct: 541 KPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----Q 380 C C K L H+ R H K + C C+K + + +LI H I P + Sbjct: 601 CSLCRKAFFEKSELIRHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 K L R + Y C C + F + H +H + P+ C CG Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719 Query: 441 ATKYQALELHVRKH 454 ++ L H R H Sbjct: 720 FSQKSQLINHQRTH 733 Score = 95.5 bits (236), Expect = 3e-19 Identities = 66/220 (30%), Positives = 92/220 (41%), Gaps = 11/220 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ + SL H R HT EKP+ C QC A + K++L H HTGEK F Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R H K + C C K +S+ +L H R + E Sbjct: 461 CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE 519 Query: 387 ALDELCLMT------REGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 C + R + Y+C C + F + H H + P+ C C Sbjct: 520 CGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKA 579 Query: 441 ATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTHIK 478 ++ L H R H Y C++CRK F L H++ Sbjct: 580 FSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLR 619 Score = 94.7 bits (234), Expect = 5e-19 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 21/221 (9%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 F C C K F K H R HT EKPY C QC A + K+ L H R HTGEK + C Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG 294 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEAL 388 C K HL H R H K + C C + +S+ NLI H R + + +E Sbjct: 295 ECGKAFSRKSHLISH-WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE-- 351 Query: 389 DELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 C K QL+ + C C + F + + RH +H + P+ C C Sbjct: 352 ---CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + +L H R H + C C K F L +H Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH 449 Score = 84.7 bits (208), Expect = 5e-16 Identities = 64/220 (29%), Positives = 86/220 (39%), Gaps = 30/220 (13%) Query: 261 SRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRK 320 +RLG K++ C C K F K SL H H + + C C K+ H R Sbjct: 200 NRLGE---KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRT 256 Query: 321 HTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHD 378 HTGEK + C C K L H +R H K + C C K +S +LI H R Sbjct: 257 HTGEKPYNCSQCGKAFSQKSQLTSH-QRTHTGEKPYECGECGKAFSRKSHLISHWR---- 311 Query: 379 PQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG 438 T G++ Y C+ C R F + + H +H + PF C CG Sbjct: 312 ----------------THTGEKP--YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECG 353 Query: 439 HGATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 ++ L H R H + C+ CRK F L H Sbjct: 354 KAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 79.0 bits (193), Expect = 3e-14 Identities = 58/200 (29%), Positives = 82/200 (41%), Gaps = 11/200 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H RTHT E Y C C + K+ L H +C Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 C + +K +L HL+ HT ++ Y C C K+F E + +H I T S Sbjct: 604 --CRKAFFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R+ L + G++ C C F + S L H H G KP++C C Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQK-SQLVNHQRIHTGEKPYRCIECGK 718 Query: 917 ATRSKSNLKAHMNRHSTEKT 936 A KS L H H+ +K+ Sbjct: 719 AFSQKSQLINHQRTHTVKKS 738 Score = 55.5 bits (132), Expect = 3e-07 Identities = 65/229 (28%), Positives = 87/229 (37%), Gaps = 47/229 (20%) Query: 99 EDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELE 158 E S LA + EC C + FS QL H I GE E L Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI-------HTGEKPYECSL--- 603 Query: 159 KKCKEDDREKAS--KRPRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKI 216 C++ EK+ + R+ EK + + E R+ K +I+ H+ I K Sbjct: 604 --CRKAFFEKSELIRHLRTHTGEKPYECN--ECRKAFREKSSLIN-----HQRIHTGEK- 653 Query: 217 VPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYC 276 P E E G S + L+P +Q + PY C C Sbjct: 654 -PFECS--ECGKAFSR--KSHLIP---HQRTHTGEKPYG-----------------CSEC 688 Query: 277 NKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K F K L H RIHT EKPY+C +C A + K+ L H R HT +K Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737 Score = 48.1 bits (113), Expect = 5e-05 Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 14/191 (7%) Query: 297 KPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH 355 K Y C + S K+ + ++ R GEK + C C K L H R + I Sbjct: 178 KYYDCDKYK-ESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236 Query: 356 CRFCKKKYSDVKNLIKHIR------DAHDPQDKKVKEALDELCLMTREGKRQLLYDCHIC 409 C C K + I H R + Q K +L R + Y+C C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 410 ERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH----PFVYVCAVCRK 465 + F + H H + P+ C CG ++ L H R H PF C C K Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPF--ECRECGK 354 Query: 466 KFVSSIRLRTH 476 F +L TH Sbjct: 355 AFSRKSQLVTH 365 Score = 46.6 bits (109), Expect = 1e-04 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 32/120 (26%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H H RTHT E Y CS+C + K+ Sbjct: 646 QRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKS--------- 696 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +L H ++HT ++ Y C C K+FS+ + +H +T+ Sbjct: 697 ---------------------QLVNHQRIHTG--EKPYRCIECGKAFSQKSQLINHQRTH 733 Score = 37.4 bits (85), Expect = 0.090 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 6/121 (4%) Query: 358 FCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNEL 417 F K D +K+ +D K ++ + R + LY+C C ++F + Sbjct: 165 FLHSKPEDTDTWLKY----YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKP 220 Query: 418 DRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRT 475 +H H F C CG + H R H Y C+ C K F +L + Sbjct: 221 SLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTS 280 Query: 476 H 476 H Sbjct: 281 H 281 >gi|239747145 PREDICTED: hypothetical protein XP_002343927 isoform 3 [Homo sapiens] Length = 738 Score = 143 bits (361), Expect = 9e-34 Identities = 106/343 (30%), Positives = 147/343 (42%), Gaps = 23/343 (6%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + F H RTHT E Y CSQC + K+ L H +C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMSTI 861 G +S K L +H + HT ++ Y C C ++FSE + +H I T Sbjct: 297 GKAFSR--KSHLISHWRTHTG--EKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + R+ QL + G + C C F + S+L RH H G KP++CS C A Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK-SELIRHQTIHTGEKPYECSECRKA 411 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 R +S+L H H+ EK H C CGK F K L SH++ HT + K F C+ C ++ Sbjct: 412 FRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGE-KPFICSKCGKAFSR 470 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE---YANVGTGELAAEV 1034 K QL+RH H KP+ C+ C + + SL H R H E+ + G Sbjct: 471 KSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNH-QRIHTGEKPYVCSECGKAFCQKSH 529 Query: 1035 LIQ-------QGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 LI + +C C +G K H + G K E Sbjct: 530 LISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Score = 138 bits (347), Expect = 4e-32 Identities = 87/284 (30%), Positives = 134/284 (47%), Gaps = 13/284 (4%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H THT E + CS+C + K+ L RH +C Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE--VSMSTI 861 G +S +K L H ++HT ++ Y C C K+F + + SH +T+ E S Sbjct: 493 GKAFS--EKLSLTNHQRIHTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + G + L + G++ +C C+ F + S L H H G KP++CSLC A Sbjct: 549 GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK-SQLNTHQRIHTGEKPYECSLCRKA 607 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 KS L H+ H+ EK + C+ C K F+ K +L +H+ +HT + K F+C+ C ++ Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE-KPFECSECGKAFSR 666 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 K L+ H H KP+ C+ C + + L H R H E+ Sbjct: 667 KSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH-QRIHTGEK 709 Score = 134 bits (336), Expect = 7e-31 Identities = 104/344 (30%), Positives = 140/344 (40%), Gaps = 23/344 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H H RTHT E Y C++C + K+ L H +C Sbjct: 292 ECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 G +S K +L H + HT + + C C K+F E + H I T S Sbjct: 352 CGKAFSR--KSQLVTHHRTHTG--TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSE 407 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R L + G++ C C F + S L H H G KPF CS C Sbjct: 408 CRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQK-SHLISHQMTHTGEKPFICSKCGK 466 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A KS L H H+ EK + C CGK F K +L +H+ +HT + K + C+ C Sbjct: 467 AFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGE-KPYVCSECGKAFC 525 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE--------EYANVGTG 1028 QK L+ H H KP+ C+ C + SL H R H E E A Sbjct: 526 QKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH-QRTHTGEKPYECRDCEKAFSQKS 584 Query: 1029 ELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 +L I G +C +C + K E RHL+ G K E Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYE 628 Score = 133 bits (335), Expect = 9e-31 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 32/272 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F ++ H R HT E Y CS+C + C K H+I + P Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF----CQKSHLISHQRTHTGEKPY 543 Query: 803 D--GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMST 860 + C + +K L H + HT ++ Y C CEK+FS+ + +H + + Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTG--EKPYECRDCEKAFSQKSQLNTHQRIH-------- 593 Query: 861 ISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRS 920 G++ +C C F + S+L RH+ H G KP++C+ C A R Sbjct: 594 --------------TGEKPYECSLCRKAFFEK-SELIRHLRTHTGEKPYECNECRKAFRE 638 Query: 921 KSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQ 980 KS+L H H+ EK C CGK F K L H+ HT + K + C+ C +QK Q Sbjct: 639 KSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGE-KPYGCSECRKAFSQKSQ 697 Query: 981 LLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L+ H H KP+RC C + + L H Sbjct: 698 LVNHQRIHTGEKPYRCIECGKAFSQKSQLINH 729 Score = 127 bits (319), Expect = 7e-29 Identities = 90/295 (30%), Positives = 131/295 (44%), Gaps = 13/295 (4%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H RTHT + CS C + K+ L RH Sbjct: 338 QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH 397 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +C C + ++ L H + HT ++ + C C K+FS+ + SH T+ Sbjct: 398 TGEKPYEC--SECRKAFRERSSLINHQRTHTG--EKPHGCIQCGKAFSQKSHLISHQMTH 453 Query: 853 HPEVSM--STISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGV 906 E S + R+ QL + G++ +C C F + S L H H G Sbjct: 454 TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS-LTNHQRIHTGE 512 Query: 907 KPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQF 966 KP+ CS C A KS+L +H H+ EK + C CGK F K +L +H+ HT + K + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGE-KPY 571 Query: 967 KCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +C C+ +QK QL H H KP+ C+ C + L RH R H E+ Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHL-RTHTGEK 625 Score = 122 bits (306), Expect = 2e-27 Identities = 75/245 (30%), Positives = 109/245 (44%), Gaps = 28/245 (11%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H RTHT E Y CS+C + K+ L H +C Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRD- 575 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C+ + K +L H ++HT ++ Y C +C K+F E + H++T+ Sbjct: 576 -CEKAFSQKSQLNTHQRIHTG--EKPYECSLCRKAFFEKSELIRHLRTH----------- 621 Query: 864 VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSN 923 G++ +C C F + S L H H G KPF+CS C A KS+ Sbjct: 622 -----------TGEKPYECNECRKAFREKSS-LINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 924 LKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLR 983 L H H+ EK + C C K F K L +H+ +HT + K ++C C +QK QL+ Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGE-KPYRCIECGKAFSQKSQLIN 728 Query: 984 HMEQH 988 H H Sbjct: 729 HQRTH 733 Score = 115 bits (288), Expect = 3e-25 Identities = 86/318 (27%), Positives = 125/318 (39%), Gaps = 37/318 (11%) Query: 762 RTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKV 821 R E LY CS+C K L +H + +I C C + P K + H + Sbjct: 199 RNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGC--GNCGKTFPQKSQFITHHRT 256 Query: 822 HTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMK 881 HT ++ Y+C C K+FS+ + SH +T+ G++ + Sbjct: 257 HTG--EKPYNCSQCGKAFSQKSQLTSHQRTH----------------------TGEKPYE 292 Query: 882 CPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDM 941 C C F + S L H H G KP+ C+ C A KSNL H H+ EK C Sbjct: 293 CGECGKAFSRK-SHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 942 CGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHY 1001 CGK F K L +H HT K F C+ C +K +L+RH H KP+ C+ C Sbjct: 352 CGKAFSRKSQLVTHHRTHTGT-KPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRK 410 Query: 1002 SCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG--GLKCPVCSFVYGT 1052 + SL H + + + G+ L + + G C C + Sbjct: 411 AFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSR 470 Query: 1053 KWEFNRHLKNKHGLKVVE 1070 K + RH + G K E Sbjct: 471 KSQLVRHQRTHTGEKPYE 488 Score = 110 bits (275), Expect = 8e-24 Identities = 67/212 (31%), Positives = 95/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A K++L H R HTGEK + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R+H K + C C+K + + LI+H+R Sbjct: 573 CRDCEKAFSQKSQLNTH-QRIHTGEKPYECSLCRKAFFEKSELIRHLR------------ 619 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y+C+ C + F+ + H +H + PF C CG ++ Sbjct: 620 --------THTGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 447 LELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ CRK F +L H Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH 701 Score = 105 bits (263), Expect = 2e-22 Identities = 70/221 (31%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 260 SSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLR 319 S ++ T K F C C K F K L H R HT EKPY+C +C A + K +L H R Sbjct: 448 SHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQR 507 Query: 320 KHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAH 377 HTGEK + C C K HL H +R H K + C C K + + +L H R Sbjct: 508 IHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECGKAFGEKSSLATHQR--- 563 Query: 378 DPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 T G++ Y+C CE+ F + + H +H + P+ C LC Sbjct: 564 -----------------THTGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + L H+R H Y C CRK F L H Sbjct: 605 RKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINH 645 Score = 97.8 bits (242), Expect = 6e-20 Identities = 60/214 (28%), Positives = 94/214 (43%), Gaps = 8/214 (3%) Query: 805 CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSM--STIS 862 CD K Q + L ++ Y C C K FS+ + H + +++ Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241 Query: 863 EVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYAT 918 + ++ Q + G++ C C F + S L H H G KP++C C A Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQK-SQLTSHQRTHTGEKPYECGECGKAF 300 Query: 919 RSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQK 978 KS+L +H H+ EK + C+ CG+ F K L +H+ +HT + K F+C C ++K Sbjct: 301 SRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGE-KPFECRECGKAFSRK 359 Query: 979 PQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 QL+ H H KPF C+ C + L RH Sbjct: 360 SQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 97.4 bits (241), Expect = 7e-20 Identities = 70/227 (30%), Positives = 96/227 (42%), Gaps = 19/227 (8%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A + K++L H R HTGEK + Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQD----- 381 C+ C K +L H +R+H K CR C K +S L+ H R + Sbjct: 321 CNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSD 379 Query: 382 -KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 +K EL + Y+C C + F+ H H + P C CG Sbjct: 380 CRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439 Query: 441 ATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRL----RTHIKE 479 ++ L H H PF +C+ C K F +L RTH E Sbjct: 440 FSQKSHLISHQMTHTGEKPF--ICSKCGKAFSRKSQLVRHQRTHTGE 484 Score = 97.1 bits (240), Expect = 1e-19 Identities = 68/215 (31%), Positives = 87/215 (40%), Gaps = 27/215 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K F C C K F K L H IHT EKPY+C +C A +++L H R HTGEK Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 C C K HL H + H K C C K +S L++H R Sbjct: 430 PHGCIQCGKAFSQKSHLISH-QMTHTGEKPFICSKCGKAFSRKSQLVRHQR--------- 479 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 T G++ Y+C C + F +L H +H + P+ C CG + Sbjct: 480 -----------THTGEKP--YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQ 526 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ C K F L TH Sbjct: 527 KSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561 Score = 95.9 bits (237), Expect = 2e-19 Identities = 62/194 (31%), Positives = 82/194 (42%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K SL H R HT EKPY+C C A + K+ LN H R HTGEK + Sbjct: 541 KPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----Q 380 C C K L H+ R H K + C C+K + + +LI H I P + Sbjct: 601 CSLCRKAFFEKSELIRHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 K L R + Y C C + F + H +H + P+ C CG Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719 Query: 441 ATKYQALELHVRKH 454 ++ L H R H Sbjct: 720 FSQKSQLINHQRTH 733 Score = 95.5 bits (236), Expect = 3e-19 Identities = 66/220 (30%), Positives = 92/220 (41%), Gaps = 11/220 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ + SL H R HT EKP+ C QC A + K++L H HTGEK F Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R H K + C C K +S+ +L H R + E Sbjct: 461 CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE 519 Query: 387 ALDELCLMT------REGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 C + R + Y+C C + F + H H + P+ C C Sbjct: 520 CGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKA 579 Query: 441 ATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTHIK 478 ++ L H R H Y C++CRK F L H++ Sbjct: 580 FSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLR 619 Score = 94.7 bits (234), Expect = 5e-19 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 21/221 (9%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 F C C K F K H R HT EKPY C QC A + K+ L H R HTGEK + C Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG 294 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEAL 388 C K HL H R H K + C C + +S+ NLI H R + + +E Sbjct: 295 ECGKAFSRKSHLISH-WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE-- 351 Query: 389 DELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 C K QL+ + C C + F + + RH +H + P+ C C Sbjct: 352 ---CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + +L H R H + C C K F L +H Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH 449 Score = 84.7 bits (208), Expect = 5e-16 Identities = 64/220 (29%), Positives = 86/220 (39%), Gaps = 30/220 (13%) Query: 261 SRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRK 320 +RLG K++ C C K F K SL H H + + C C K+ H R Sbjct: 200 NRLGE---KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRT 256 Query: 321 HTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHD 378 HTGEK + C C K L H +R H K + C C K +S +LI H R Sbjct: 257 HTGEKPYNCSQCGKAFSQKSQLTSH-QRTHTGEKPYECGECGKAFSRKSHLISHWR---- 311 Query: 379 PQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG 438 T G++ Y C+ C R F + + H +H + PF C CG Sbjct: 312 ----------------THTGEKP--YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECG 353 Query: 439 HGATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 ++ L H R H + C+ CRK F L H Sbjct: 354 KAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 79.0 bits (193), Expect = 3e-14 Identities = 58/200 (29%), Positives = 82/200 (41%), Gaps = 11/200 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H RTHT E Y C C + K+ L H +C Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 C + +K +L HL+ HT ++ Y C C K+F E + +H I T S Sbjct: 604 --CRKAFFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R+ L + G++ C C F + S L H H G KP++C C Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQK-SQLVNHQRIHTGEKPYRCIECGK 718 Query: 917 ATRSKSNLKAHMNRHSTEKT 936 A KS L H H+ +K+ Sbjct: 719 AFSQKSQLINHQRTHTVKKS 738 Score = 55.5 bits (132), Expect = 3e-07 Identities = 65/229 (28%), Positives = 87/229 (37%), Gaps = 47/229 (20%) Query: 99 EDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELE 158 E S LA + EC C + FS QL H I GE E L Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI-------HTGEKPYECSL--- 603 Query: 159 KKCKEDDREKAS--KRPRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKI 216 C++ EK+ + R+ EK + + E R+ K +I+ H+ I K Sbjct: 604 --CRKAFFEKSELIRHLRTHTGEKPYECN--ECRKAFREKSSLIN-----HQRIHTGEK- 653 Query: 217 VPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYC 276 P E E G S + L+P +Q + PY C C Sbjct: 654 -PFECS--ECGKAFSR--KSHLIP---HQRTHTGEKPYG-----------------CSEC 688 Query: 277 NKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K F K L H RIHT EKPY+C +C A + K+ L H R HT +K Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737 Score = 48.1 bits (113), Expect = 5e-05 Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 14/191 (7%) Query: 297 KPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH 355 K Y C + S K+ + ++ R GEK + C C K L H R + I Sbjct: 178 KYYDCDKYK-ESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236 Query: 356 CRFCKKKYSDVKNLIKHIR------DAHDPQDKKVKEALDELCLMTREGKRQLLYDCHIC 409 C C K + I H R + Q K +L R + Y+C C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 410 ERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH----PFVYVCAVCRK 465 + F + H H + P+ C CG ++ L H R H PF C C K Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPF--ECRECGK 354 Query: 466 KFVSSIRLRTH 476 F +L TH Sbjct: 355 AFSRKSQLVTH 365 Score = 46.6 bits (109), Expect = 1e-04 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 32/120 (26%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H H RTHT E Y CS+C + K+ Sbjct: 646 QRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKS--------- 696 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +L H ++HT ++ Y C C K+FS+ + +H +T+ Sbjct: 697 ---------------------QLVNHQRIHTG--EKPYRCIECGKAFSQKSQLINHQRTH 733 Score = 37.4 bits (85), Expect = 0.090 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 6/121 (4%) Query: 358 FCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNEL 417 F K D +K+ +D K ++ + R + LY+C C ++F + Sbjct: 165 FLHSKPEDTDTWLKY----YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKP 220 Query: 418 DRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRT 475 +H H F C CG + H R H Y C+ C K F +L + Sbjct: 221 SLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTS 280 Query: 476 H 476 H Sbjct: 281 H 281 >gi|188497655 zinc finger protein 84 [Homo sapiens] Length = 738 Score = 143 bits (361), Expect = 9e-34 Identities = 106/343 (30%), Positives = 147/343 (42%), Gaps = 23/343 (6%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + F H RTHT E Y CSQC + K+ L H +C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMSTI 861 G +S K L +H + HT ++ Y C C ++FSE + +H I T Sbjct: 297 GKAFSR--KSHLISHWRTHTG--EKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + R+ QL + G + C C F + S+L RH H G KP++CS C A Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK-SELIRHQTIHTGEKPYECSECRKA 411 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 R +S+L H H+ EK H C CGK F K L SH++ HT + K F C+ C ++ Sbjct: 412 FRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGE-KPFICSKCGKAFSR 470 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE---YANVGTGELAAEV 1034 K QL+RH H KP+ C+ C + + SL H R H E+ + G Sbjct: 471 KSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNH-QRIHTGEKPYVCSECGKAFCQKSH 529 Query: 1035 LIQ-------QGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 LI + +C C +G K H + G K E Sbjct: 530 LISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Score = 138 bits (347), Expect = 4e-32 Identities = 87/284 (30%), Positives = 134/284 (47%), Gaps = 13/284 (4%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H THT E + CS+C + K+ L RH +C Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE--VSMSTI 861 G +S +K L H ++HT ++ Y C C K+F + + SH +T+ E S Sbjct: 493 GKAFS--EKLSLTNHQRIHTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + G + L + G++ +C C+ F + S L H H G KP++CSLC A Sbjct: 549 GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK-SQLNTHQRIHTGEKPYECSLCRKA 607 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 KS L H+ H+ EK + C+ C K F+ K +L +H+ +HT + K F+C+ C ++ Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE-KPFECSECGKAFSR 666 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 K L+ H H KP+ C+ C + + L H R H E+ Sbjct: 667 KSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH-QRIHTGEK 709 Score = 134 bits (336), Expect = 7e-31 Identities = 104/344 (30%), Positives = 140/344 (40%), Gaps = 23/344 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H H RTHT E Y C++C + K+ L H +C Sbjct: 292 ECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 G +S K +L H + HT + + C C K+F E + H I T S Sbjct: 352 CGKAFSR--KSQLVTHHRTHTG--TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSE 407 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R L + G++ C C F + S L H H G KPF CS C Sbjct: 408 CRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQK-SHLISHQMTHTGEKPFICSKCGK 466 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A KS L H H+ EK + C CGK F K +L +H+ +HT + K + C+ C Sbjct: 467 AFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGE-KPYVCSECGKAFC 525 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE--------EYANVGTG 1028 QK L+ H H KP+ C+ C + SL H R H E E A Sbjct: 526 QKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH-QRTHTGEKPYECRDCEKAFSQKS 584 Query: 1029 ELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 +L I G +C +C + K E RHL+ G K E Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYE 628 Score = 133 bits (335), Expect = 9e-31 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 32/272 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F ++ H R HT E Y CS+C + C K H+I + P Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF----CQKSHLISHQRTHTGEKPY 543 Query: 803 D--GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMST 860 + C + +K L H + HT ++ Y C CEK+FS+ + +H + + Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTG--EKPYECRDCEKAFSQKSQLNTHQRIH-------- 593 Query: 861 ISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRS 920 G++ +C C F + S+L RH+ H G KP++C+ C A R Sbjct: 594 --------------TGEKPYECSLCRKAFFEK-SELIRHLRTHTGEKPYECNECRKAFRE 638 Query: 921 KSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQ 980 KS+L H H+ EK C CGK F K L H+ HT + K + C+ C +QK Q Sbjct: 639 KSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGE-KPYGCSECRKAFSQKSQ 697 Query: 981 LLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L+ H H KP+RC C + + L H Sbjct: 698 LVNHQRIHTGEKPYRCIECGKAFSQKSQLINH 729 Score = 127 bits (319), Expect = 7e-29 Identities = 90/295 (30%), Positives = 131/295 (44%), Gaps = 13/295 (4%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H RTHT + CS C + K+ L RH Sbjct: 338 QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH 397 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +C C + ++ L H + HT ++ + C C K+FS+ + SH T+ Sbjct: 398 TGEKPYEC--SECRKAFRERSSLINHQRTHTG--EKPHGCIQCGKAFSQKSHLISHQMTH 453 Query: 853 HPEVSM--STISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGV 906 E S + R+ QL + G++ +C C F + S L H H G Sbjct: 454 TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS-LTNHQRIHTGE 512 Query: 907 KPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQF 966 KP+ CS C A KS+L +H H+ EK + C CGK F K +L +H+ HT + K + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGE-KPY 571 Query: 967 KCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +C C+ +QK QL H H KP+ C+ C + L RH R H E+ Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHL-RTHTGEK 625 Score = 122 bits (306), Expect = 2e-27 Identities = 75/245 (30%), Positives = 109/245 (44%), Gaps = 28/245 (11%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H RTHT E Y CS+C + K+ L H +C Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRD- 575 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C+ + K +L H ++HT ++ Y C +C K+F E + H++T+ Sbjct: 576 -CEKAFSQKSQLNTHQRIHTG--EKPYECSLCRKAFFEKSELIRHLRTH----------- 621 Query: 864 VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSN 923 G++ +C C F + S L H H G KPF+CS C A KS+ Sbjct: 622 -----------TGEKPYECNECRKAFREKSS-LINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 924 LKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLR 983 L H H+ EK + C C K F K L +H+ +HT + K ++C C +QK QL+ Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGE-KPYRCIECGKAFSQKSQLIN 728 Query: 984 HMEQH 988 H H Sbjct: 729 HQRTH 733 Score = 115 bits (288), Expect = 3e-25 Identities = 86/318 (27%), Positives = 125/318 (39%), Gaps = 37/318 (11%) Query: 762 RTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKV 821 R E LY CS+C K L +H + +I C C + P K + H + Sbjct: 199 RNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGC--GNCGKTFPQKSQFITHHRT 256 Query: 822 HTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMK 881 HT ++ Y+C C K+FS+ + SH +T+ G++ + Sbjct: 257 HTG--EKPYNCSQCGKAFSQKSQLTSHQRTH----------------------TGEKPYE 292 Query: 882 CPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDM 941 C C F + S L H H G KP+ C+ C A KSNL H H+ EK C Sbjct: 293 CGECGKAFSRK-SHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 942 CGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHY 1001 CGK F K L +H HT K F C+ C +K +L+RH H KP+ C+ C Sbjct: 352 CGKAFSRKSQLVTHHRTHTGT-KPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRK 410 Query: 1002 SCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG--GLKCPVCSFVYGT 1052 + SL H + + + G+ L + + G C C + Sbjct: 411 AFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSR 470 Query: 1053 KWEFNRHLKNKHGLKVVE 1070 K + RH + G K E Sbjct: 471 KSQLVRHQRTHTGEKPYE 488 Score = 110 bits (275), Expect = 8e-24 Identities = 67/212 (31%), Positives = 95/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A K++L H R HTGEK + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R+H K + C C+K + + LI+H+R Sbjct: 573 CRDCEKAFSQKSQLNTH-QRIHTGEKPYECSLCRKAFFEKSELIRHLR------------ 619 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y+C+ C + F+ + H +H + PF C CG ++ Sbjct: 620 --------THTGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 447 LELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ CRK F +L H Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH 701 Score = 105 bits (263), Expect = 2e-22 Identities = 70/221 (31%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 260 SSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLR 319 S ++ T K F C C K F K L H R HT EKPY+C +C A + K +L H R Sbjct: 448 SHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQR 507 Query: 320 KHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAH 377 HTGEK + C C K HL H +R H K + C C K + + +L H R Sbjct: 508 IHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECGKAFGEKSSLATHQR--- 563 Query: 378 DPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 T G++ Y+C CE+ F + + H +H + P+ C LC Sbjct: 564 -----------------THTGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + L H+R H Y C CRK F L H Sbjct: 605 RKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINH 645 Score = 97.8 bits (242), Expect = 6e-20 Identities = 60/214 (28%), Positives = 94/214 (43%), Gaps = 8/214 (3%) Query: 805 CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSM--STIS 862 CD K Q + L ++ Y C C K FS+ + H + +++ Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241 Query: 863 EVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYAT 918 + ++ Q + G++ C C F + S L H H G KP++C C A Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQK-SQLTSHQRTHTGEKPYECGECGKAF 300 Query: 919 RSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQK 978 KS+L +H H+ EK + C+ CG+ F K L +H+ +HT + K F+C C ++K Sbjct: 301 SRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGE-KPFECRECGKAFSRK 359 Query: 979 PQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 QL+ H H KPF C+ C + L RH Sbjct: 360 SQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 97.4 bits (241), Expect = 7e-20 Identities = 70/227 (30%), Positives = 96/227 (42%), Gaps = 19/227 (8%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A + K++L H R HTGEK + Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQD----- 381 C+ C K +L H +R+H K CR C K +S L+ H R + Sbjct: 321 CNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSD 379 Query: 382 -KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 +K EL + Y+C C + F+ H H + P C CG Sbjct: 380 CRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439 Query: 441 ATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRL----RTHIKE 479 ++ L H H PF +C+ C K F +L RTH E Sbjct: 440 FSQKSHLISHQMTHTGEKPF--ICSKCGKAFSRKSQLVRHQRTHTGE 484 Score = 97.1 bits (240), Expect = 1e-19 Identities = 68/215 (31%), Positives = 87/215 (40%), Gaps = 27/215 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K F C C K F K L H IHT EKPY+C +C A +++L H R HTGEK Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 C C K HL H + H K C C K +S L++H R Sbjct: 430 PHGCIQCGKAFSQKSHLISH-QMTHTGEKPFICSKCGKAFSRKSQLVRHQR--------- 479 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 T G++ Y+C C + F +L H +H + P+ C CG + Sbjct: 480 -----------THTGEKP--YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQ 526 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ C K F L TH Sbjct: 527 KSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561 Score = 95.9 bits (237), Expect = 2e-19 Identities = 62/194 (31%), Positives = 82/194 (42%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K SL H R HT EKPY+C C A + K+ LN H R HTGEK + Sbjct: 541 KPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----Q 380 C C K L H+ R H K + C C+K + + +LI H I P + Sbjct: 601 CSLCRKAFFEKSELIRHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 K L R + Y C C + F + H +H + P+ C CG Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719 Query: 441 ATKYQALELHVRKH 454 ++ L H R H Sbjct: 720 FSQKSQLINHQRTH 733 Score = 95.5 bits (236), Expect = 3e-19 Identities = 66/220 (30%), Positives = 92/220 (41%), Gaps = 11/220 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ + SL H R HT EKP+ C QC A + K++L H HTGEK F Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R H K + C C K +S+ +L H R + E Sbjct: 461 CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE 519 Query: 387 ALDELCLMT------REGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 C + R + Y+C C + F + H H + P+ C C Sbjct: 520 CGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKA 579 Query: 441 ATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTHIK 478 ++ L H R H Y C++CRK F L H++ Sbjct: 580 FSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLR 619 Score = 94.7 bits (234), Expect = 5e-19 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 21/221 (9%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 F C C K F K H R HT EKPY C QC A + K+ L H R HTGEK + C Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG 294 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEAL 388 C K HL H R H K + C C + +S+ NLI H R + + +E Sbjct: 295 ECGKAFSRKSHLISH-WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE-- 351 Query: 389 DELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 C K QL+ + C C + F + + RH +H + P+ C C Sbjct: 352 ---CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + +L H R H + C C K F L +H Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH 449 Score = 84.7 bits (208), Expect = 5e-16 Identities = 64/220 (29%), Positives = 86/220 (39%), Gaps = 30/220 (13%) Query: 261 SRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRK 320 +RLG K++ C C K F K SL H H + + C C K+ H R Sbjct: 200 NRLGE---KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRT 256 Query: 321 HTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHD 378 HTGEK + C C K L H +R H K + C C K +S +LI H R Sbjct: 257 HTGEKPYNCSQCGKAFSQKSQLTSH-QRTHTGEKPYECGECGKAFSRKSHLISHWR---- 311 Query: 379 PQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG 438 T G++ Y C+ C R F + + H +H + PF C CG Sbjct: 312 ----------------THTGEKP--YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECG 353 Query: 439 HGATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 ++ L H R H + C+ CRK F L H Sbjct: 354 KAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 79.0 bits (193), Expect = 3e-14 Identities = 58/200 (29%), Positives = 82/200 (41%), Gaps = 11/200 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H RTHT E Y C C + K+ L H +C Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 C + +K +L HL+ HT ++ Y C C K+F E + +H I T S Sbjct: 604 --CRKAFFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R+ L + G++ C C F + S L H H G KP++C C Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQK-SQLVNHQRIHTGEKPYRCIECGK 718 Query: 917 ATRSKSNLKAHMNRHSTEKT 936 A KS L H H+ +K+ Sbjct: 719 AFSQKSQLINHQRTHTVKKS 738 Score = 55.5 bits (132), Expect = 3e-07 Identities = 65/229 (28%), Positives = 87/229 (37%), Gaps = 47/229 (20%) Query: 99 EDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELE 158 E S LA + EC C + FS QL H I GE E L Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI-------HTGEKPYECSL--- 603 Query: 159 KKCKEDDREKAS--KRPRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKI 216 C++ EK+ + R+ EK + + E R+ K +I+ H+ I K Sbjct: 604 --CRKAFFEKSELIRHLRTHTGEKPYECN--ECRKAFREKSSLIN-----HQRIHTGEK- 653 Query: 217 VPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYC 276 P E E G S + L+P +Q + PY C C Sbjct: 654 -PFECS--ECGKAFSR--KSHLIP---HQRTHTGEKPYG-----------------CSEC 688 Query: 277 NKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K F K L H RIHT EKPY+C +C A + K+ L H R HT +K Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737 Score = 48.1 bits (113), Expect = 5e-05 Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 14/191 (7%) Query: 297 KPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH 355 K Y C + S K+ + ++ R GEK + C C K L H R + I Sbjct: 178 KYYDCDKYK-ESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236 Query: 356 CRFCKKKYSDVKNLIKHIR------DAHDPQDKKVKEALDELCLMTREGKRQLLYDCHIC 409 C C K + I H R + Q K +L R + Y+C C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 410 ERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH----PFVYVCAVCRK 465 + F + H H + P+ C CG ++ L H R H PF C C K Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPF--ECRECGK 354 Query: 466 KFVSSIRLRTH 476 F +L TH Sbjct: 355 AFSRKSQLVTH 365 Score = 46.6 bits (109), Expect = 1e-04 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 32/120 (26%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H H RTHT E Y CS+C + K+ Sbjct: 646 QRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKS--------- 696 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +L H ++HT ++ Y C C K+FS+ + +H +T+ Sbjct: 697 ---------------------QLVNHQRIHTG--EKPYRCIECGKAFSQKSQLINHQRTH 733 Score = 37.4 bits (85), Expect = 0.090 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 6/121 (4%) Query: 358 FCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNEL 417 F K D +K+ +D K ++ + R + LY+C C ++F + Sbjct: 165 FLHSKPEDTDTWLKY----YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKP 220 Query: 418 DRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRT 475 +H H F C CG + H R H Y C+ C K F +L + Sbjct: 221 SLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTS 280 Query: 476 H 476 H Sbjct: 281 H 281 >gi|188497653 zinc finger protein 84 [Homo sapiens] Length = 738 Score = 143 bits (361), Expect = 9e-34 Identities = 106/343 (30%), Positives = 147/343 (42%), Gaps = 23/343 (6%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + F H RTHT E Y CSQC + K+ L H +C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMSTI 861 G +S K L +H + HT ++ Y C C ++FSE + +H I T Sbjct: 297 GKAFSR--KSHLISHWRTHTG--EKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + R+ QL + G + C C F + S+L RH H G KP++CS C A Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK-SELIRHQTIHTGEKPYECSECRKA 411 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 R +S+L H H+ EK H C CGK F K L SH++ HT + K F C+ C ++ Sbjct: 412 FRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGE-KPFICSKCGKAFSR 470 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE---YANVGTGELAAEV 1034 K QL+RH H KP+ C+ C + + SL H R H E+ + G Sbjct: 471 KSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNH-QRIHTGEKPYVCSECGKAFCQKSH 529 Query: 1035 LIQ-------QGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 LI + +C C +G K H + G K E Sbjct: 530 LISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Score = 138 bits (347), Expect = 4e-32 Identities = 87/284 (30%), Positives = 134/284 (47%), Gaps = 13/284 (4%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H THT E + CS+C + K+ L RH +C Sbjct: 433 CIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSEC 492 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE--VSMSTI 861 G +S +K L H ++HT ++ Y C C K+F + + SH +T+ E S Sbjct: 493 GKAFS--EKLSLTNHQRIHTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSEC 548 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 + G + L + G++ +C C+ F + S L H H G KP++CSLC A Sbjct: 549 GKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK-SQLNTHQRIHTGEKPYECSLCRKA 607 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 KS L H+ H+ EK + C+ C K F+ K +L +H+ +HT + K F+C+ C ++ Sbjct: 608 FFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE-KPFECSECGKAFSR 666 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 K L+ H H KP+ C+ C + + L H R H E+ Sbjct: 667 KSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH-QRIHTGEK 709 Score = 134 bits (336), Expect = 7e-31 Identities = 104/344 (30%), Positives = 140/344 (40%), Gaps = 23/344 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H H RTHT E Y C++C + K+ L H +C Sbjct: 292 ECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 G +S K +L H + HT + + C C K+F E + H I T S Sbjct: 352 CGKAFSR--KSQLVTHHRTHTG--TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSE 407 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R L + G++ C C F + S L H H G KPF CS C Sbjct: 408 CRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQK-SHLISHQMTHTGEKPFICSKCGK 466 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A KS L H H+ EK + C CGK F K +L +H+ +HT + K + C+ C Sbjct: 467 AFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGE-KPYVCSECGKAFC 525 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE--------EYANVGTG 1028 QK L+ H H KP+ C+ C + SL H R H E E A Sbjct: 526 QKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH-QRTHTGEKPYECRDCEKAFSQKS 584 Query: 1029 ELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLKNKHGLKVVE 1070 +L I G +C +C + K E RHL+ G K E Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYE 628 Score = 133 bits (335), Expect = 9e-31 Identities = 83/272 (30%), Positives = 121/272 (44%), Gaps = 32/272 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F ++ H R HT E Y CS+C + C K H+I + P Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF----CQKSHLISHQRTHTGEKPY 543 Query: 803 D--GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMST 860 + C + +K L H + HT ++ Y C CEK+FS+ + +H + + Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTG--EKPYECRDCEKAFSQKSQLNTHQRIH-------- 593 Query: 861 ISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRS 920 G++ +C C F + S+L RH+ H G KP++C+ C A R Sbjct: 594 --------------TGEKPYECSLCRKAFFEK-SELIRHLRTHTGEKPYECNECRKAFRE 638 Query: 921 KSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQ 980 KS+L H H+ EK C CGK F K L H+ HT + K + C+ C +QK Q Sbjct: 639 KSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGE-KPYGCSECRKAFSQKSQ 697 Query: 981 LLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L+ H H KP+RC C + + L H Sbjct: 698 LVNHQRIHTGEKPYRCIECGKAFSQKSQLINH 729 Score = 127 bits (319), Expect = 7e-29 Identities = 90/295 (30%), Positives = 131/295 (44%), Gaps = 13/295 (4%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H RTHT + CS C + K+ L RH Sbjct: 338 QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH 397 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +C C + ++ L H + HT ++ + C C K+FS+ + SH T+ Sbjct: 398 TGEKPYEC--SECRKAFRERSSLINHQRTHTG--EKPHGCIQCGKAFSQKSHLISHQMTH 453 Query: 853 HPEVSM--STISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGV 906 E S + R+ QL + G++ +C C F + S L H H G Sbjct: 454 TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLS-LTNHQRIHTGE 512 Query: 907 KPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQF 966 KP+ CS C A KS+L +H H+ EK + C CGK F K +L +H+ HT + K + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGE-KPY 571 Query: 967 KCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +C C+ +QK QL H H KP+ C+ C + L RH R H E+ Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHL-RTHTGEK 625 Score = 122 bits (306), Expect = 2e-27 Identities = 75/245 (30%), Positives = 109/245 (44%), Gaps = 28/245 (11%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F + H H RTHT E Y CS+C + K+ L H +C Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRD- 575 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C+ + K +L H ++HT ++ Y C +C K+F E + H++T+ Sbjct: 576 -CEKAFSQKSQLNTHQRIHTG--EKPYECSLCRKAFFEKSELIRHLRTH----------- 621 Query: 864 VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSN 923 G++ +C C F + S L H H G KPF+CS C A KS+ Sbjct: 622 -----------TGEKPYECNECRKAFREKSS-LINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 924 LKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLR 983 L H H+ EK + C C K F K L +H+ +HT + K ++C C +QK QL+ Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGE-KPYRCIECGKAFSQKSQLIN 728 Query: 984 HMEQH 988 H H Sbjct: 729 HQRTH 733 Score = 115 bits (288), Expect = 3e-25 Identities = 86/318 (27%), Positives = 125/318 (39%), Gaps = 37/318 (11%) Query: 762 RTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKV 821 R E LY CS+C K L +H + +I C C + P K + H + Sbjct: 199 RNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGC--GNCGKTFPQKSQFITHHRT 256 Query: 822 HTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMK 881 HT ++ Y+C C K+FS+ + SH +T+ G++ + Sbjct: 257 HTG--EKPYNCSQCGKAFSQKSQLTSHQRTH----------------------TGEKPYE 292 Query: 882 CPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDM 941 C C F + S L H H G KP+ C+ C A KSNL H H+ EK C Sbjct: 293 CGECGKAFSRK-SHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE 351 Query: 942 CGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHY 1001 CGK F K L +H HT K F C+ C +K +L+RH H KP+ C+ C Sbjct: 352 CGKAFSRKSQLVTHHRTHTGT-KPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRK 410 Query: 1002 SCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG--GLKCPVCSFVYGT 1052 + SL H + + + G+ L + + G C C + Sbjct: 411 AFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSR 470 Query: 1053 KWEFNRHLKNKHGLKVVE 1070 K + RH + G K E Sbjct: 471 KSQLVRHQRTHTGEKPYE 488 Score = 110 bits (275), Expect = 8e-24 Identities = 67/212 (31%), Positives = 95/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A K++L H R HTGEK + Sbjct: 513 KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYE 572 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R+H K + C C+K + + LI+H+R Sbjct: 573 CRDCEKAFSQKSQLNTH-QRIHTGEKPYECSLCRKAFFEKSELIRHLR------------ 619 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y+C+ C + F+ + H +H + PF C CG ++ Sbjct: 620 --------THTGEKP--YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSH 669 Query: 447 LELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ CRK F +L H Sbjct: 670 LIPHQRTHTGEKPYGCSECRKAFSQKSQLVNH 701 Score = 105 bits (263), Expect = 2e-22 Identities = 70/221 (31%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 260 SSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLR 319 S ++ T K F C C K F K L H R HT EKPY+C +C A + K +L H R Sbjct: 448 SHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQR 507 Query: 320 KHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAH 377 HTGEK + C C K HL H +R H K + C C K + + +L H R Sbjct: 508 IHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECGKAFGEKSSLATHQR--- 563 Query: 378 DPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 T G++ Y+C CE+ F + + H +H + P+ C LC Sbjct: 564 -----------------THTGEKP--YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLC 604 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + L H+R H Y C CRK F L H Sbjct: 605 RKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINH 645 Score = 97.8 bits (242), Expect = 6e-20 Identities = 60/214 (28%), Positives = 94/214 (43%), Gaps = 8/214 (3%) Query: 805 CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSM--STIS 862 CD K Q + L ++ Y C C K FS+ + H + +++ Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241 Query: 863 EVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYAT 918 + ++ Q + G++ C C F + S L H H G KP++C C A Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQK-SQLTSHQRTHTGEKPYECGECGKAF 300 Query: 919 RSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQK 978 KS+L +H H+ EK + C+ CG+ F K L +H+ +HT + K F+C C ++K Sbjct: 301 SRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGE-KPFECRECGKAFSRK 359 Query: 979 PQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 QL+ H H KPF C+ C + L RH Sbjct: 360 SQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 97.4 bits (241), Expect = 7e-20 Identities = 70/227 (30%), Positives = 96/227 (42%), Gaps = 19/227 (8%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L +H R HT EKPY+C +C A + K++L H R HTGEK + Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQD----- 381 C+ C K +L H +R+H K CR C K +S L+ H R + Sbjct: 321 CNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSD 379 Query: 382 -KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 +K EL + Y+C C + F+ H H + P C CG Sbjct: 380 CRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKA 439 Query: 441 ATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRL----RTHIKE 479 ++ L H H PF +C+ C K F +L RTH E Sbjct: 440 FSQKSHLISHQMTHTGEKPF--ICSKCGKAFSRKSQLVRHQRTHTGE 484 Score = 97.1 bits (240), Expect = 1e-19 Identities = 68/215 (31%), Positives = 87/215 (40%), Gaps = 27/215 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K F C C K F K L H IHT EKPY+C +C A +++L H R HTGEK Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 C C K HL H + H K C C K +S L++H R Sbjct: 430 PHGCIQCGKAFSQKSHLISH-QMTHTGEKPFICSKCGKAFSRKSQLVRHQR--------- 479 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 T G++ Y+C C + F +L H +H + P+ C CG + Sbjct: 480 -----------THTGEKP--YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQ 526 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 L H R H Y C+ C K F L TH Sbjct: 527 KSHLISHQRTHTGEKPYECSECGKAFGEKSSLATH 561 Score = 95.9 bits (237), Expect = 2e-19 Identities = 62/194 (31%), Positives = 82/194 (42%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K SL H R HT EKPY+C C A + K+ LN H R HTGEK + Sbjct: 541 KPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----Q 380 C C K L H+ R H K + C C+K + + +LI H I P + Sbjct: 601 CSLCRKAFFEKSELIRHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 K L R + Y C C + F + H +H + P+ C CG Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719 Query: 441 ATKYQALELHVRKH 454 ++ L H R H Sbjct: 720 FSQKSQLINHQRTH 733 Score = 95.5 bits (236), Expect = 3e-19 Identities = 66/220 (30%), Positives = 92/220 (41%), Gaps = 11/220 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ + SL H R HT EKP+ C QC A + K++L H HTGEK F Sbjct: 401 KPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFI 460 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L H +R H K + C C K +S+ +L H R + E Sbjct: 461 CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE 519 Query: 387 ALDELCLMT------REGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 C + R + Y+C C + F + H H + P+ C C Sbjct: 520 CGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKA 579 Query: 441 ATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTHIK 478 ++ L H R H Y C++CRK F L H++ Sbjct: 580 FSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLR 619 Score = 94.7 bits (234), Expect = 5e-19 Identities = 68/221 (30%), Positives = 90/221 (40%), Gaps = 21/221 (9%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 F C C K F K H R HT EKPY C QC A + K+ L H R HTGEK + C Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG 294 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEAL 388 C K HL H R H K + C C + +S+ NLI H R + + +E Sbjct: 295 ECGKAFSRKSHLISH-WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRE-- 351 Query: 389 DELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 C K QL+ + C C + F + + RH +H + P+ C C Sbjct: 352 ---CGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + +L H R H + C C K F L +H Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISH 449 Score = 84.7 bits (208), Expect = 5e-16 Identities = 64/220 (29%), Positives = 86/220 (39%), Gaps = 30/220 (13%) Query: 261 SRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRK 320 +RLG K++ C C K F K SL H H + + C C K+ H R Sbjct: 200 NRLGE---KLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRT 256 Query: 321 HTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHD 378 HTGEK + C C K L H +R H K + C C K +S +LI H R Sbjct: 257 HTGEKPYNCSQCGKAFSQKSQLTSH-QRTHTGEKPYECGECGKAFSRKSHLISHWR---- 311 Query: 379 PQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG 438 T G++ Y C+ C R F + + H +H + PF C CG Sbjct: 312 ----------------THTGEKP--YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECG 353 Query: 439 HGATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 ++ L H R H + C+ CRK F L H Sbjct: 354 KAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH 393 Score = 79.0 bits (193), Expect = 3e-14 Identities = 58/200 (29%), Positives = 82/200 (41%), Gaps = 11/200 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H RTHT E Y C C + K+ L H +C Sbjct: 544 ECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSL 603 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 C + +K +L HL+ HT ++ Y C C K+F E + +H I T S Sbjct: 604 --CRKAFFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R+ L + G++ C C F + S L H H G KP++C C Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQK-SQLVNHQRIHTGEKPYRCIECGK 718 Query: 917 ATRSKSNLKAHMNRHSTEKT 936 A KS L H H+ +K+ Sbjct: 719 AFSQKSQLINHQRTHTVKKS 738 Score = 55.5 bits (132), Expect = 3e-07 Identities = 65/229 (28%), Positives = 87/229 (37%), Gaps = 47/229 (20%) Query: 99 EDSPLAPEEGNSLPPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELE 158 E S LA + EC C + FS QL H I GE E L Sbjct: 554 EKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI-------HTGEKPYECSL--- 603 Query: 159 KKCKEDDREKAS--KRPRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKI 216 C++ EK+ + R+ EK + + E R+ K +I+ H+ I K Sbjct: 604 --CRKAFFEKSELIRHLRTHTGEKPYECN--ECRKAFREKSSLIN-----HQRIHTGEK- 653 Query: 217 VPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYC 276 P E E G S + L+P +Q + PY C C Sbjct: 654 -PFECS--ECGKAFSR--KSHLIP---HQRTHTGEKPYG-----------------CSEC 688 Query: 277 NKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K F K L H RIHT EKPY+C +C A + K+ L H R HT +K Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737 Score = 48.1 bits (113), Expect = 5e-05 Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 14/191 (7%) Query: 297 KPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH 355 K Y C + S K+ + ++ R GEK + C C K L H R + I Sbjct: 178 KYYDCDKYK-ESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236 Query: 356 CRFCKKKYSDVKNLIKHIR------DAHDPQDKKVKEALDELCLMTREGKRQLLYDCHIC 409 C C K + I H R + Q K +L R + Y+C C Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296 Query: 410 ERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH----PFVYVCAVCRK 465 + F + H H + P+ C CG ++ L H R H PF C C K Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPF--ECRECGK 354 Query: 466 KFVSSIRLRTH 476 F +L TH Sbjct: 355 AFSRKSQLVTH 365 Score = 46.6 bits (109), Expect = 1e-04 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 32/120 (26%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + H H RTHT E Y CS+C + K+ Sbjct: 646 QRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKS--------- 696 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 +L H ++HT ++ Y C C K+FS+ + +H +T+ Sbjct: 697 ---------------------QLVNHQRIHTG--EKPYRCIECGKAFSQKSQLINHQRTH 733 Score = 37.4 bits (85), Expect = 0.090 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 6/121 (4%) Query: 358 FCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNEL 417 F K D +K+ +D K ++ + R + LY+C C ++F + Sbjct: 165 FLHSKPEDTDTWLKY----YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKP 220 Query: 418 DRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRT 475 +H H F C CG + H R H Y C+ C K F +L + Sbjct: 221 SLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTS 280 Query: 476 H 476 H Sbjct: 281 H 281 >gi|157167158 zinc finger protein 808 [Homo sapiens] Length = 903 Score = 143 bits (361), Expect = 9e-34 Identities = 101/350 (28%), Positives = 143/350 (40%), Gaps = 35/350 (10%) Query: 718 VLNSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHY 777 V N + + ++ RI +C CGK F Q H H R HT E Y C C Sbjct: 543 VCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDK 602 Query: 778 SSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEK 837 K+ L+ H +C CD + +L H ++HT +++Y C C K Sbjct: 603 VFGQKSALESHKRIHTGEKPYRCQV--CDTAFTWNSQLARHTRIHTG--EKTYKCNECGK 658 Query: 838 SFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGK--------RAMKCPYCDFYF 889 +FS + H + + E S +V + + + K + KC C F Sbjct: 659 TFSYKSSLVWHRRLHGGEKSYKC--KVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTF 716 Query: 890 MKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSK 949 N S L H H G KP+KCS C K+ L H HS EK + C+ CG F+ Sbjct: 717 -SNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHW 775 Query: 950 GTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSL 1009 +L H+ LHT + K +KCTVCD + L RH+ H + KP++C C + N L Sbjct: 776 SSLVYHRRLHTGE-KSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHL 834 Query: 1010 KRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRH 1059 RH+ + TGE KC C V+ K RH Sbjct: 835 SRHH----------RIHTGEKP---------YKCEACDKVFSRKSHLKRH 865 Score = 132 bits (333), Expect = 2e-30 Identities = 99/377 (26%), Positives = 151/377 (40%), Gaps = 59/377 (15%) Query: 725 KQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNC 784 +Q + S +R+ +C+ C K F + H R H+ E Y C++C + ++ Sbjct: 354 QQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSS 413 Query: 785 LKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRL 844 L RH I KC + CD K L+ H ++HT ++ Y C VC+ +F+ + Sbjct: 414 LARHHILHTGEKPYKC--EECDKVFSQKSTLERHKRIHTG--EKPYKCKVCDTAFTCNSQ 469 Query: 845 IKSH--IKTNHPEVSMSTISEVLGRRVQL-------------------------KGLIGK 877 + H I T + + RR L L+ Sbjct: 470 LARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQCGNTFRHRASLVYH 529 Query: 878 RAM-------KCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNR 930 R + KC C+ FM+N S L H H KP+KC+ C A +S+L H Sbjct: 530 RRLHTLEKSYKCTVCNKVFMRN-SVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRL 588 Query: 931 HSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVS 990 H+ EK + C+ C K F K L+SHK +HT + K ++C VCD QL RH H Sbjct: 589 HTGEKPYKCEACDKVFGQKSALESHKRIHTGE-KPYRCQVCDTAFTWNSQLARHTRIHTG 647 Query: 991 FKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVY 1050 K ++C C + + SL H R H E+ KC VC + Sbjct: 648 EKTYKCNECGKTFSYKSSLVWH-RRLHGGEK------------------SYKCKVCDKAF 688 Query: 1051 GTKWEFNRHLKNKHGLK 1067 + +H + G+K Sbjct: 689 VCRSYVAKHTRIHSGMK 705 Score = 129 bits (325), Expect = 1e-29 Identities = 97/382 (25%), Positives = 157/382 (41%), Gaps = 77/382 (20%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRH-------------- 788 +C+ CGKLF ++ + H R HT E Y C +C S K+ L H Sbjct: 260 KCDVCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNE 319 Query: 789 ---VIQKHSNILL-----------KCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPV 834 V +++S +++ KC + C + + L H ++HT + + Y C + Sbjct: 320 CGKVFRQNSALVIHKAIHTGEKPYKC--NECGKAFNQQSHLSRHQRLHTGV--KPYKCKI 375 Query: 835 CEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLI--------GKRAMKCPYCD 886 CEK+F+ + +H + + E + G+ + + G++ KC CD Sbjct: 376 CEKAFACHSYLANHTRIHSGEKTYKC--NECGKAFNHQSSLARHHILHTGEKPYKCEECD 433 Query: 887 FYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKF 946 F + S L+RH H G KP+KC +C+ A S L H H+ EKT+ C+ C K F Sbjct: 434 KVFSQK-STLERHKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTF 492 Query: 947 KSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCH------ 1000 + +L H+ LH+ + K +KC C T + L+ H H K ++C C+ Sbjct: 493 SRRSSLLCHRRLHSGE-KPYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRN 551 Query: 1001 ---------------YSCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPV 1045 Y CN G + +N++ + + TGE KC Sbjct: 552 SVLAVHTRIHTAKKPYKCNECG---KAFNQQSHLSRHRRLHTGEKP---------YKCEA 599 Query: 1046 CSFVYGTKWEFNRHLKNKHGLK 1067 C V+G K H + G K Sbjct: 600 CDKVFGQKSALESHKRIHTGEK 621 Score = 127 bits (320), Expect = 5e-29 Identities = 87/265 (32%), Positives = 120/265 (45%), Gaps = 15/265 (5%) Query: 764 HTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHT 823 H RE + C++ + + L++H I + KC D C K L H + HT Sbjct: 225 HMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKC--DVCGKLFNHKQYLACHRRCHT 282 Query: 824 ALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLI-------G 876 ++ Y C C KSFS + H + H V +E Q L+ G Sbjct: 283 G--EKPYKCKECGKSFSYKSSLTCHHRL-HTGVKPYKCNECGKVFRQNSALVIHKAIHTG 339 Query: 877 KRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKT 936 ++ KC C F + S L RH H GVKP+KC +CE A S L H HS EKT Sbjct: 340 EKPYKCNECGKAFNQQ-SHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKT 398 Query: 937 HLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRC 996 + C+ CGK F + +L H +LHT + K +KC CD +QK L RH H KP++C Sbjct: 399 YKCNECGKAFNHQSSLARHHILHTGE-KPYKCEECDKVFSQKSTLERHKRIHTGEKPYKC 457 Query: 997 AHCHYSCNISGSLKRHYNRKHPNEE 1021 C + + L RH R H E+ Sbjct: 458 KVCDTAFTCNSQLARH-RRIHTGEK 481 Score = 126 bits (317), Expect = 1e-28 Identities = 94/348 (27%), Positives = 148/348 (42%), Gaps = 34/348 (9%) Query: 696 THQPDSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLCERIRKVYGD-------------- 741 T++ + C A H+S + A +L++ +K CE KV+ Sbjct: 398 TYKCNECGKAFNHQSSL-ARHHILHTGEKPYK----CEECDKVFSQKSTLERHKRIHTGE 452 Query: 742 --LECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLK 799 +C+ C F H R HT E Y C++C + ++ L H K Sbjct: 453 KPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPYK 512 Query: 800 CPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVS 857 C + C + + L H ++HT ++SY C VC K F + ++ H I T Sbjct: 513 C--NQCGNTFRHRASLVYHRRLHTL--EKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYK 568 Query: 858 MSTISEVLGRRVQLKGL----IGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSL 913 + + ++ L G++ KC CD F + S L+ H H G KP++C + Sbjct: 569 CNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQK-SALESHKRIHTGEKPYRCQV 627 Query: 914 CEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDY 973 C+ A S L H H+ EKT+ C+ CGK F K +L H+ LH + K +KC VCD Sbjct: 628 CDTAFTWNSQLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGE-KSYKCKVCDK 686 Query: 974 TAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 + + +H H KP++C C + + SL H R H E+ Sbjct: 687 AFVCRSYVAKHTRIHSGMKPYKCNECSKTFSNRSSLVCH-RRIHSGEK 733 Score = 122 bits (306), Expect = 2e-27 Identities = 80/274 (29%), Positives = 127/274 (46%), Gaps = 24/274 (8%) Query: 728 NTSLCERIRKVYGD--LECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCL 785 N+ L R G+ +C CGK F Y+ H R H E Y C C + + ++ + Sbjct: 635 NSQLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYV 694 Query: 786 KRHVIQKHSNIL-LKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRL 844 +H + HS + KC + C + ++ L H ++H+ ++ Y C C K+FS+ Sbjct: 695 AKHT-RIHSGMKPYKC--NECSKTFSNRSSLVCHRRIHSG--EKPYKCSECSKTFSQKAT 749 Query: 845 IKSHIKTNHPEVSMST----------ISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGS 894 + H + + E S V RR+ G+++ KC CD F++N S Sbjct: 750 LLCHRRLHSGEKPYKCNDCGNTFRHWSSLVYHRRLHT----GEKSYKCTVCDKAFVRN-S 804 Query: 895 DLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKS 954 L RHI H KP+KC+ C A +S+L H H+ EK + C+ C K F K LK Sbjct: 805 YLARHIRIHTAEKPYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKR 864 Query: 955 HKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQH 988 H+++HT + K +KC C + + L+ H H Sbjct: 865 HRIIHTGE-KPYKCNECGKAFSDRSTLIHHQAIH 897 Score = 122 bits (305), Expect = 3e-27 Identities = 77/275 (28%), Positives = 121/275 (44%), Gaps = 12/275 (4%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C+ C F + H R HT E Y C++C + K+ L H KC Sbjct: 625 CQVCDTAFTWNSQLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKV- 683 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMSTI 861 CD + + + H ++H+ + + Y C C K+FS + H I + S Sbjct: 684 -CDKAFVCRSYVAKHTRIHSGM--KPYKCNECSKTFSNRSSLVCHRRIHSGEKPYKCSEC 740 Query: 862 SEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 S+ ++ L + G++ KC C F ++ S L H H G K +KC++C+ A Sbjct: 741 SKTFSQKATLLCHRRLHSGEKPYKCNDCGNTF-RHWSSLVYHRRLHTGEKSYKCTVCDKA 799 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQ 977 S L H+ H+ EK + C+ CGK F + L H +HT + K +KC CD ++ Sbjct: 800 FVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHLSRHHRIHTGE-KPYKCEACDKVFSR 858 Query: 978 KPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 K L RH H KP++C C + + +L H Sbjct: 859 KSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHH 893 Score = 107 bits (267), Expect = 7e-23 Identities = 75/230 (32%), Positives = 103/230 (44%), Gaps = 22/230 (9%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C+KVF K +L++H RIHT EKPY+C C A + L H R HTGEK + Sbjct: 593 KPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYK 652 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C T K L H R+H K + C+ C K + + KH R + K E Sbjct: 653 CNECGKTFSYKSSLVWH-RRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNE 711 Query: 387 ALDELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 C T + L+ Y C C + F + H +H + P+ C Sbjct: 712 -----CSKTFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCN 766 Query: 436 LCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVHGA 483 CG+ + +L H R H Y C VC K FV + L HI+ +H A Sbjct: 767 DCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIR-IHTA 815 Score = 106 bits (264), Expect = 2e-22 Identities = 68/233 (29%), Positives = 102/233 (43%), Gaps = 11/233 (4%) Query: 254 YEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKAN 313 ++Q + R T K + C+ C K F +K SL H R+HT KPYKC +C + Sbjct: 270 HKQYLACHRRCHTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSA 329 Query: 314 LNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIK 371 L +H HTGEK + C+ C + HL H +R+H +K + C+ C+K ++ L Sbjct: 330 LVIHKAIHTGEKPYKCNECGKAFNQQSHLSRH-QRLHTGVKPYKCKICEKAFACHSYLAN 388 Query: 372 HIRDAHDPQDKKVKEALDELCLMTREGKRQLL------YDCHICERKFKNELDRDRHMLV 425 H R + K E + + +L Y C C++ F + +RH + Sbjct: 389 HTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKCEECDKVFSQKSTLERHKRI 448 Query: 426 HGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 H + P+ C++C T L H R H Y C CRK F L H Sbjct: 449 HTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCH 501 Score = 105 bits (262), Expect = 3e-22 Identities = 73/221 (33%), Positives = 99/221 (44%), Gaps = 13/221 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C+KVF K +L+ H RIHT EKPYKC C A + L H R HTGEK + Sbjct: 425 KPYKCEECDKVFSQKSTLERHKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYK 484 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQD----- 381 C+ C T + L H R+H K + C C + +L+ H R H + Sbjct: 485 CNECRKTFSRRSSLLCH-RRLHSGEKPYKCNQCGNTFRHRASLVYH-RRLHTLEKSYKCT 542 Query: 382 --KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 KV L + TR + Y C+ C + F + RH +H + P+ CE C Sbjct: 543 VCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDK 602 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIK 478 + ALE H R H Y C VC F + +L H + Sbjct: 603 VFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTR 643 Score = 105 bits (261), Expect = 4e-22 Identities = 67/223 (30%), Positives = 102/223 (45%), Gaps = 12/223 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C K+F K L H R HT EKPYKC +C + + K++L H R HTG K + Sbjct: 257 KQYKCDVCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYK 316 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQDKKV 384 C+ C L +H + +H K + C C K ++ +L +H + P K+ Sbjct: 317 CNECGKVFRQNSALVIH-KAIHTGEKPYKCNECGKAFNQQSHLSRHQRLHTGVKPYKCKI 375 Query: 385 KEAL----DELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 E L TR + Y C+ C + F ++ RH ++H + P+ CE C Sbjct: 376 CEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKCEECDKV 435 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 ++ LE H R H Y C VC F + +L H + +H Sbjct: 436 FSQKSTLERHKRIHTGEKPYKCKVCDTAFTCNSQLARH-RRIH 477 Score = 97.1 bits (240), Expect = 1e-19 Identities = 62/195 (31%), Positives = 90/195 (46%), Gaps = 9/195 (4%) Query: 268 LKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-F 326 +K + C C+K F + SL H RIH+ EKPYKC +CS + KA L H R H+GEK + Sbjct: 704 MKPYKCNECSKTFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPY 763 Query: 327 ACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVK 385 C+ C T L H R+H K + C C K + L +HIR + K Sbjct: 764 KCNDCGNTFRHWSSLVYH-RRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCN 822 Query: 386 E---ALDELCLMTREGK---RQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 E A +E ++R + + Y C C++ F + RH ++H + P+ C CG Sbjct: 823 ECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGK 882 Query: 440 GATKYQALELHVRKH 454 + L H H Sbjct: 883 AFSDRSTLIHHQAIH 897 Score = 82.0 bits (201), Expect = 3e-15 Identities = 52/168 (30%), Positives = 77/168 (45%), Gaps = 11/168 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C+K F K +L H R+H+ EKPYKC C ++L H R HTGEK + Sbjct: 733 KPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVYHRRLHTGEKSYK 792 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C + +L HI R+H K + C C K +++ +L +H R H + E Sbjct: 793 CTVCDKAFVRNSYLARHI-RIHTAEKPYKCNECGKAFNEQSHLSRHHR-IHTGEKPYKCE 850 Query: 387 ALDELCLMTREGKRQLL-------YDCHICERKFKNELDRDRHMLVHG 427 A D++ KR + Y C+ C + F + H +HG Sbjct: 851 ACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQAIHG 898 Score = 75.5 bits (184), Expect = 3e-13 Identities = 58/208 (27%), Positives = 85/208 (40%), Gaps = 11/208 (5%) Query: 734 RIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKH 793 RI +C C K F + H R H+ E Y CS+C + K L H Sbjct: 699 RIHSGMKPYKCNECSKTFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHS 758 Query: 794 SNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNH 853 KC + C + L H ++HT ++SY C VC+K+F + + HI+ + Sbjct: 759 GEKPYKC--NDCGNTFRHWSSLVYHRRLHTG--EKSYKCTVCDKAFVRNSYLARHIRIHT 814 Query: 854 PE--VSMSTISEVLGRRVQLKGL----IGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVK 907 E + + + L G++ KC CD F + S L+RH H G K Sbjct: 815 AEKPYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRK-SHLKRHRIIHTGEK 873 Query: 908 PFKCSLCEYATRSKSNLKAHMNRHSTEK 935 P+KC+ C A +S L H H K Sbjct: 874 PYKCNECGKAFSDRSTLIHHQAIHGIGK 901 Score = 67.0 bits (162), Expect = 1e-10 Identities = 48/176 (27%), Positives = 69/176 (39%), Gaps = 20/176 (11%) Query: 892 NGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGT 951 N S L + H K F C+ A S L+ H H +K + CD+CGK F K Sbjct: 214 NSSLLPQKQEVHMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQY 273 Query: 952 LKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKR 1011 L H+ HT + K +KC C + + K L H H KP++C C + +L Sbjct: 274 LACHRRCHTGE-KPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVI 332 Query: 1012 HYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 H + TGE KC C + + +RH + G+K Sbjct: 333 H----------KAIHTGEKP---------YKCNECGKAFNQQSHLSRHQRLHTGVK 369 Score = 60.8 bits (146), Expect = 8e-09 Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K + C C K F + L H RIHT EKPYKC C + K++L H HTGEK Sbjct: 814 TAEKPYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEK 873 Query: 326 -FACDYCSFTCLSKGHLKVHIERVH 349 + C+ C + L +H + +H Sbjct: 874 PYKCNECGKAFSDRSTL-IHHQAIH 897 Score = 52.4 bits (124), Expect = 3e-06 Identities = 26/58 (44%), Positives = 33/58 (56%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEKF 326 K + CE C+KVF K L+ H IHT EKPYKC +C A + ++ L H H KF Sbjct: 845 KPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQAIHGIGKF 902 Score = 34.7 bits (78), Expect = 0.58 Identities = 19/64 (29%), Positives = 29/64 (45%) Query: 725 KQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNC 784 +Q + S RI +CE C K+F + H H HT E Y C++C + ++ Sbjct: 830 EQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRST 889 Query: 785 LKRH 788 L H Sbjct: 890 LIHH 893 >gi|57165428 zinc finger protein 28 [Homo sapiens] Length = 665 Score = 143 bits (360), Expect = 1e-33 Identities = 87/285 (30%), Positives = 132/285 (46%), Gaps = 13/285 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C+ C K F Y + H HT E Y C++C ++ L RH + KC Sbjct: 359 KCKVCDKAFAYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARHHRLHTAEKPYKC-- 416 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 + CD K L+ H ++HT ++ Y C VC+K+F D + H + T + Sbjct: 417 EECDKVFRCKSHLERHRRIHTG--EKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNE 474 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V + L K ++ KC C+ F + S ++RH H G KP+KC +C+ Sbjct: 475 CGKVFSTKANLACHHKLHTAEKPYKCEECEKVFSRK-SHMERHRRIHTGEKPYKCKVCDK 533 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A R S+L H H+ EK + C+ CGK F+ +L H+ LHT + K +KC C T + Sbjct: 534 AFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTGE-KPYKCNECGKTFS 592 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 Q L+ H H KP++C C N L +H R H E+ Sbjct: 593 QMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQH-QRVHTGEK 636 Score = 138 bits (348), Expect = 3e-32 Identities = 86/285 (30%), Positives = 133/285 (46%), Gaps = 13/285 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C+ C K F + H HT E Y C++C + L RH +C Sbjct: 275 KCKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECGKVFNRLSTLARHRRLHTGEKPYEC-- 332 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 + C+ K L+ H ++HT ++ Y C VC+K+F+ + + H I T + Sbjct: 333 EECEKVFSRKSHLERHKRIHTG--EKPYKCKVCDKAFAYNSYLAKHSIIHTGEKPYKCNE 390 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V ++ L + ++ KC CD F + S L+RH H G KP+KC +C+ Sbjct: 391 CGKVFNQQSTLARHHRLHTAEKPYKCEECDKVF-RCKSHLERHRRIHTGEKPYKCKVCDK 449 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A RS S L H H+ EK ++C+ CGK F +K L H LHTA+ K +KC C+ + Sbjct: 450 AFRSDSCLTEHQRVHTGEKPYMCNECGKVFSTKANLACHHKLHTAE-KPYKCEECEKVFS 508 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +K + RH H KP++C C + L +H R H E+ Sbjct: 509 RKSHMERHRRIHTGEKPYKCKVCDKAFRRDSHLAQH-QRVHTGEK 552 Score = 136 bits (342), Expect = 1e-31 Identities = 89/279 (31%), Positives = 128/279 (45%), Gaps = 29/279 (10%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +CE C K+F + H + H R HT E Y C C + + +CL H C Sbjct: 415 KCEECDKVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNE 474 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 G +ST K L H K+HTA ++ Y C CEK FS KSH++ + Sbjct: 475 CGKVFST--KANLACHHKLHTA--EKPYKCEECEKVFSR----KSHMERH---------- 516 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 RR+ G++ KC CD F ++ S L +H H G KP+KC+ C R S Sbjct: 517 ----RRIHT----GEKPYKCKVCDKAFRRD-SHLAQHQRVHTGEKPYKCNECGKTFRQTS 567 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 +L H H+ EK + C+ CGK F +L H LH+ + K +KC C Q+ L Sbjct: 568 SLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYHHRLHSGE-KPYKCNECGKVFNQQAHLA 626 Query: 983 RHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +H H KP++C C + + +L H+ R H E+ Sbjct: 627 QHQRVHTGEKPYKCNECGKTFSQMSNLVYHH-RLHSGEK 664 Score = 132 bits (331), Expect = 3e-30 Identities = 90/331 (27%), Positives = 130/331 (39%), Gaps = 31/331 (9%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F + +H HT + Y C +C K+ L+ H I KC Sbjct: 219 KCNECGKIFGHNTSLFLHKALHTADKPYECEECDKVFSRKSHLETHKIIYTGGKPYKCKV 278 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 CD + L H +HT ++ Y C C K F+ + H + T Sbjct: 279 --CDKAFTCNSYLAKHTIIHTG--EKPYKCNECGKVFNRLSTLARHRRLHTGEKPYECEE 334 Query: 861 ISEVLGRRVQLKG----LIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V R+ L+ G++ KC CD F N S L +H H G KP+KC+ C Sbjct: 335 CEKVFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYN-SYLAKHSIIHTGEKPYKCNECGK 393 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 +S L H H+ EK + C+ C K F+ K L+ H+ +HT + K +KC VCD Sbjct: 394 VFNQQSTLARHHRLHTAEKPYKCEECDKVFRCKSHLERHRRIHTGE-KPYKCKVCDKAFR 452 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLI 1036 L H H KP+ C C + +L H+ + Y Sbjct: 453 SDSCLTEHQRVHTGEKPYMCNECGKVFSTKANLACHHKLHTAEKPY-------------- 498 Query: 1037 QQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 KC C V+ K RH + G K Sbjct: 499 -----KCEECEKVFSRKSHMERHRRIHTGEK 524 Score = 103 bits (258), Expect = 8e-22 Identities = 81/313 (25%), Positives = 122/313 (38%), Gaps = 37/313 (11%) Query: 764 HTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHT 823 H RE + C + S + LK+H I KC G ++ K L H + H Sbjct: 156 HMREKSFQCIESGKSFNCSSLLKKHQITHLEEKQCKCDVYGKVFN--QKRYLACHRRSH- 212 Query: 824 ALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCP 883 +D++ Y C C K F + + H K H + +C Sbjct: 213 -IDEKPYKCNECGKIFGHNTSLFLH-KALHT---------------------ADKPYECE 249 Query: 884 YCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCG 943 CD F + S L+ H + G KP+KC +C+ A S L H H+ EK + C+ CG Sbjct: 250 ECDKVFSRK-SHLETHKIIYTGGKPYKCKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECG 308 Query: 944 KKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSC 1003 K F TL H+ LHT + K ++C C+ ++K L RH H KP++C C + Sbjct: 309 KVFNRLSTLARHRRLHTGE-KPYECEECEKVFSRKSHLERHKRIHTGEKPYKCKVCDKAF 367 Query: 1004 NISGSLKRH---------YNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKW 1054 + L +H Y + + T + + KC C V+ K Sbjct: 368 AYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARHHRLHTAEKPYKCEECDKVFRCKS 427 Query: 1055 EFNRHLKNKHGLK 1067 RH + G K Sbjct: 428 HLERHRRIHTGEK 440 Score = 102 bits (255), Expect = 2e-21 Identities = 67/215 (31%), Positives = 97/215 (45%), Gaps = 27/215 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K + CE C+KVF+ K L+ H RIHT EKPYKC C A + L H R HTGEK Sbjct: 409 TAEKPYKCEECDKVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEK 468 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 + C+ C +K +L H ++H K + C C+K +S ++ +H R Sbjct: 469 PYMCNECGKVFSTKANLACH-HKLHTAEKPYKCEECEKVFSRKSHMERHRR--------- 518 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 G++ Y C +C++ F+ + +H VH + P+ C CG + Sbjct: 519 -----------IHTGEKP--YKCKVCDKAFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQ 565 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 +L +H R H Y C C K F L H Sbjct: 566 TSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYH 600 Score = 97.4 bits (241), Expect = 7e-20 Identities = 61/194 (31%), Positives = 86/194 (44%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C KVF K +L H ++HT EKPYKC +C + K+++ H R HTGEK + Sbjct: 468 KPYMCNECGKVFSTKANLACHHKLHTAEKPYKCEECEKVFSRKSHMERHRRIHTGEKPYK 527 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C HL H +RVH K + C C K + +LI H R + K E Sbjct: 528 CKVCDKAFRRDSHLAQH-QRVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTGEKPYKCNE 586 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 + L R + Y C+ C + F + +H VH + P+ C CG Sbjct: 587 CGKTFSQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVHTGEKPYKCNECGKT 646 Query: 441 ATKYQALELHVRKH 454 ++ L H R H Sbjct: 647 FSQMSNLVYHHRLH 660 Score = 96.7 bits (239), Expect = 1e-19 Identities = 65/224 (29%), Positives = 98/224 (43%), Gaps = 14/224 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C KVF +L H R+HT EKPY+C +C + K++L H R HTGEK + Sbjct: 300 KPYKCNECGKVFNRLSTLARHRRLHTGEKPYECEECEKVFSRKSHLERHKRIHTGEKPYK 359 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C +L H +H K + C C K ++ L +H R H + E Sbjct: 360 CKVCDKAFAYNSYLAKH-SIIHTGEKPYKCNECGKVFNQQSTLARHHR-LHTAEKPYKCE 417 Query: 387 ALDEL--CLMTREGKRQL-----LYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 D++ C E R++ Y C +C++ F+++ H VH + P+ C CG Sbjct: 418 ECDKVFRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNECGK 477 Query: 440 GATKYQALELHVRKHPF--VYVCAVCRKKFVSSIRLRTHIKEVH 481 + L H + H Y C C K F + H + +H Sbjct: 478 VFSTKANLACHHKLHTAEKPYKCEECEKVFSRKSHMERH-RRIH 520 Score = 95.5 bits (236), Expect = 3e-19 Identities = 74/223 (33%), Positives = 98/223 (43%), Gaps = 12/223 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C KVF K L+ H RIHT EKPYKC C A A + L H HTGEK + Sbjct: 328 KPYECEECEKVFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYNSYLAKHSIIHTGEKPYK 387 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQDKKV 384 C+ C + L H R+H K + C C K + +L +H I P KV Sbjct: 388 CNECGKVFNQQSTLARH-HRLHTAEKPYKCEECDKVFRCKSHLERHRRIHTGEKPYKCKV 446 Query: 385 --KEALDELCLM--TREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 K + CL R + Y C+ C + F + + H +H + P+ CE C Sbjct: 447 CDKAFRSDSCLTEHQRVHTGEKPYMCNECGKVFSTKANLACHHKLHTAEKPYKCEECEKV 506 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 ++ +E H R H Y C VC K F L H + VH Sbjct: 507 FSRKSHMERHRRIHTGEKPYKCKVCDKAFRRDSHLAQH-QRVH 548 Score = 89.7 bits (221), Expect = 2e-17 Identities = 69/248 (27%), Positives = 97/248 (39%), Gaps = 39/248 (15%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK--- 325 K + CE C+KVF K L+ H I+T KPYKC C A + L H HTGEK Sbjct: 244 KPYECEECDKVFSRKSHLETHKIIYTGGKPYKCKVCDKAFTCNSYLAKHTIIHTGEKPYK 303 Query: 326 --------------------------FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRF 358 + C+ C K HL+ H +R+H K + C+ Sbjct: 304 CNECGKVFNRLSTLARHRRLHTGEKPYECEECEKVFSRKSHLERH-KRIHTGEKPYKCKV 362 Query: 359 CKKKYSDVKNLIKH--IRDAHDP----QDKKVKEALDELCLMTREGKRQLLYDCHICERK 412 C K ++ L KH I P + KV L R + Y C C++ Sbjct: 363 CDKAFAYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARHHRLHTAEKPYKCEECDKV 422 Query: 413 FKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSS 470 F+ + +RH +H + P+ C++C L H R H Y+C C K F + Sbjct: 423 FRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTEHQRVHTGEKPYMCNECGKVFSTK 482 Query: 471 IRLRTHIK 478 L H K Sbjct: 483 ANLACHHK 490 Score = 89.4 bits (220), Expect = 2e-17 Identities = 64/232 (27%), Positives = 94/232 (40%), Gaps = 17/232 (7%) Query: 258 MKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVH 317 +K ++ + K C+ KVF K L H R H +EKPYKC +C +L +H Sbjct: 177 LKKHQITHLEEKQCKCDVYGKVFNQKRYLACHRRSHIDEKPYKCNECGKIFGHNTSLFLH 236 Query: 318 LRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH--IR 374 HT +K + C+ C K HL+ H C+ C K ++ L KH I Sbjct: 237 KALHTADKPYECEECDKVFSRKSHLETHKIIYTGGKPYKCKVCDKAFTCNSYLAKHTIIH 296 Query: 375 DAHDP----QDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKW 430 P + KV L L R + Y+C CE+ F + +RH +H + Sbjct: 297 TGEKPYKCNECGKVFNRLSTLARHRRLHTGEKPYECEECEKVFSRKSHLERHKRIHTGEK 356 Query: 431 PFACELCGHGATKYQALELHVRKHPFV------YVCAVCRKKFVSSIRLRTH 476 P+ C++C K A ++ KH + Y C C K F L H Sbjct: 357 PYKCKVC----DKAFAYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARH 404 Score = 86.3 bits (212), Expect = 2e-16 Identities = 67/250 (26%), Positives = 104/250 (41%), Gaps = 22/250 (8%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K+F SL H +HT +KPY+C +C + K++L H +TG K + Sbjct: 216 KPYKCNECGKIFGHNTSLFLHKALHTADKPYECEECDKVFSRKSHLETHKIIYTGGKPYK 275 Query: 328 CDYC--SFTCLS--KGHLKVHI-ERVHKKIKQHCRFCKKKYSDVKNLIKH--IRDAHDPQ 380 C C +FTC S H +H E+ +K C C K ++ + L +H + P Sbjct: 276 CKVCDKAFTCNSYLAKHTIIHTGEKPYK-----CNECGKVFNRLSTLARHRRLHTGEKPY 330 Query: 381 D----KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACEL 436 + +KV L R + Y C +C++ F +H ++H + P+ C Sbjct: 331 ECEECEKVFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYNSYLAKHSIIHTGEKPYKCNE 390 Query: 437 CGHGATKYQALELHVRKHPF--VYVCAVCRKKFVSSIRLRTHIKEVHGAAQ--EALVFTS 492 CG + L H R H Y C C K F L H + +H + + V Sbjct: 391 CGKVFNQQSTLARHHRLHTAEKPYKCEECDKVFRCKSHLERH-RRIHTGEKPYKCKVCDK 449 Query: 493 SINQSFCLLE 502 + CL E Sbjct: 450 AFRSDSCLTE 459 Score = 72.8 bits (177), Expect = 2e-12 Identities = 42/119 (35%), Positives = 60/119 (50%), Gaps = 3/119 (2%) Query: 258 MKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVH 317 M+ R T K + C+ C+K F+ L H R+HT EKPYKC +C ++L +H Sbjct: 513 MERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIH 572 Query: 318 LRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIR 374 R HTGEK + C+ C T L H R+H K + C C K ++ +L +H R Sbjct: 573 RRLHTGEKPYKCNECGKTFSQMSSLVYH-HRLHSGEKPYKCNECGKVFNQQAHLAQHQR 630 Score = 58.2 bits (139), Expect = 5e-08 Identities = 26/57 (45%), Positives = 33/57 (57%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K + C C KVF + L H R+HT EKPYKC +C + +NL H R H+GEK Sbjct: 608 KPYKCNECGKVFNQQAHLAQHQRVHTGEKPYKCNECGKTFSQMSNLVYHHRLHSGEK 664 Score = 53.9 bits (128), Expect = 9e-07 Identities = 53/203 (26%), Positives = 78/203 (38%), Gaps = 18/203 (8%) Query: 292 IHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHK 350 +H EK ++C + + + L H H EK CD K +L H R H Sbjct: 155 VHMREKSFQCIESGKSFNCSSLLKKHQITHLEEKQCKCDVYGKVFNQKRYLACH-RRSHI 213 Query: 351 KIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQD----KKV---KEALDELCLMTREGKR 400 K + C C K + +L H + A P + KV K L+ ++ GK Sbjct: 214 DEKPYKCNECGKIFGHNTSLFLHKALHTADKPYECEECDKVFSRKSHLETHKIIYTGGKP 273 Query: 401 QLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVY 458 Y C +C++ F +H ++H + P+ C CG + L H R H Y Sbjct: 274 ---YKCKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECGKVFNRLSTLARHRRLHTGEKPY 330 Query: 459 VCAVCRKKFVSSIRLRTHIKEVH 481 C C K F L H K +H Sbjct: 331 ECEECEKVFSRKSHLERH-KRIH 352 Score = 53.5 bits (127), Expect = 1e-06 Identities = 42/134 (31%), Positives = 55/134 (41%), Gaps = 10/134 (7%) Query: 922 SNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQL 981 S L N H EK+ C GK F LK H++ H + KQ KC V QK L Sbjct: 147 SLLTQKRNVHMREKSFQCIESGKSFNCSSLLKKHQITHLEE-KQCKCDVYGKVFNQKRYL 205 Query: 982 LRHMEQHVSFKPFRCAHCHYSCNISGSLKRH-----YNRKHPNEEYANVGT--GELAAEV 1034 H H+ KP++C C + SL H ++ + EE V + L Sbjct: 206 ACHRRSHIDEKPYKCNECGKIFGHNTSLFLHKALHTADKPYECEECDKVFSRKSHLETHK 265 Query: 1035 LIQQGG--LKCPVC 1046 +I GG KC VC Sbjct: 266 IIYTGGKPYKCKVC 279 Score = 45.8 bits (107), Expect = 3e-04 Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 4/125 (3%) Query: 717 KVLNSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCH 776 KV + ++ + + +R+ +C CGK F +H R HT E Y C++C Sbjct: 529 KVCDKAFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTGEKPYKCNECG 588 Query: 777 YSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCE 836 + + L H KC + C + L H +VHT ++ Y C C Sbjct: 589 KTFSQMSSLVYHHRLHSGEKPYKC--NECGKVFNQQAHLAQHQRVHTG--EKPYKCNECG 644 Query: 837 KSFSE 841 K+FS+ Sbjct: 645 KTFSQ 649 >gi|169213999 PREDICTED: similar to hCG1778601 isoform 1 [Homo sapiens] Length = 700 Score = 142 bits (359), Expect = 2e-33 Identities = 100/341 (29%), Positives = 148/341 (43%), Gaps = 23/341 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F Q + H R HT E Y C +C K+ L+RH KC Sbjct: 309 KCNECGKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYKCKV 368 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 CD + L H+ +HT ++ Y C C K+F E+ + H I T + Sbjct: 369 --CDKAFRHDSHLAQHIVIHTR--EKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNE 424 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V ++ L + G++ KC CD F + S L+RH H G KP+KC +C+ Sbjct: 425 CGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRK-SHLERHRRIHTGEKPYKCKVCDK 483 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A R S+L H H+ EK + C+ CGK F +L HK++HT + K++KC C + Sbjct: 484 AFRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGE-KRYKCNECGKSFN 542 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE---------EYANVGT 1027 K L H H KP++C C L H+ R H E + N+ + Sbjct: 543 HKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHH-RLHTGEKPYKCEECDKVFNIKS 601 Query: 1028 G-ELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 E+ V + KC VC +G +H + G K Sbjct: 602 HLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEK 642 Score = 135 bits (340), Expect = 2e-31 Identities = 92/302 (30%), Positives = 132/302 (43%), Gaps = 35/302 (11%) Query: 720 NSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSS 779 +SL KK L E+ K C+ CGK F + + H R HT E Y C++C Sbjct: 208 SSLFKKHQIIHLGEKQYK------CDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVF 261 Query: 780 ITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSF 839 K L RH + KC + C + DK L H +HT ++ Y C C K F Sbjct: 262 NKKAYLARHYRRHTGEKPYKC--NECGKTFSDKSALLVHKTIHTG--EKPYKCNECGKVF 317 Query: 840 SEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRH 899 ++ + H + + G++ +C CD F + S L+RH Sbjct: 318 NQQSNLARHHRVH----------------------TGEKPYQCKECDKVFSRK-SYLERH 354 Query: 900 IWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLH 959 H G KP+KC +C+ A R S+L H+ H+ EK + C+ CGK F L HK +H Sbjct: 355 RRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNECGKTFGENSALLVHKTIH 414 Query: 960 TADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPN 1019 T + K +KC C Q+ L RH H KP++C C + L+RH R H Sbjct: 415 TGE-KPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERH-RRIHTG 472 Query: 1020 EE 1021 E+ Sbjct: 473 EK 474 Score = 131 bits (330), Expect = 3e-30 Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 47/366 (12%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK+F + + H R HT E Y C++C + K+ L H KC Sbjct: 254 CNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNEC 313 Query: 804 G--------------------------CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEK 837 G CD K L+ H ++HT ++ Y C VC+K Sbjct: 314 GKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTG--EKPYKCKVCDK 371 Query: 838 SFSEDRLIKSHIKTNHPEVSM------STISEVLGRRVQLKGLIGKRAMKCPYCDFYFMK 891 +F D + HI + E T E V G++ KC C F + Sbjct: 372 AFRHDSHLAQHIVIHTREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQ 431 Query: 892 NGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGT 951 S+L RH H G KP+KC C+ KS+L+ H H+ EK + C +C K F+ Sbjct: 432 Q-SNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSH 490 Query: 952 LKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKR 1011 L H ++HT + K +KC C T Q L+ H H K ++C C S N SL Sbjct: 491 LAQHTVIHTGE-KPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAY 549 Query: 1012 HYNRKHPNEEYANVG--------TGELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLK 1061 H+ R H E+ +LA + G KC C V+ K H + Sbjct: 550 HH-RLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRR 608 Query: 1062 NKHGLK 1067 G K Sbjct: 609 VHTGEK 614 Score = 123 bits (308), Expect = 1e-27 Identities = 81/276 (29%), Positives = 118/276 (42%), Gaps = 12/276 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F Q + H R HT E Y C +C K+ L+RH KC Sbjct: 421 KCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKV 480 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 CD + L H +HT ++ Y C C K+F ++ + H I T + Sbjct: 481 --CDKAFRRDSHLAQHTVIHTG--EKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNE 536 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + + L + G++ KC C F + S L H H G KP+KC C+ Sbjct: 537 CGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVF-RTQSQLACHHRLHTGEKPYKCEECDK 595 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 KS+L+ H H+ EK + C +C K F L H+ +HT + K +KC VCD Sbjct: 596 VFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGE-KPYKCKVCDKAFK 654 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L +H H KPF+C+ C + +L H Sbjct: 655 CYSHLAQHTRIHTGEKPFKCSECGKAFRAQSTLIHH 690 Score = 110 bits (274), Expect = 1e-23 Identities = 76/270 (28%), Positives = 114/270 (42%), Gaps = 12/270 (4%) Query: 725 KQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNC 784 +Q N + R+ +C+ C K+F + H + H R HT E Y C C + + Sbjct: 431 QQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSH 490 Query: 785 LKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRL 844 L +H + KC + C + L H +HT ++ Y C C KSF+ Sbjct: 491 LAQHTVIHTGEKPYKC--NECGKTFVQNSSLVMHKVIHTG--EKRYKCNECGKSFNHKSS 546 Query: 845 IKSH--IKTNHPEVSMSTISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQR 898 + H + T + +V + QL + G++ KC CD F S L+ Sbjct: 547 LAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIK-SHLEI 605 Query: 899 HIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLL 958 H H G KP+KC +C+ A S L H H+ EK + C +C K FK L H + Sbjct: 606 HRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEKPYKCKVCDKAFKCYSHLAQHTRI 665 Query: 959 HTADGKQFKCTVCDYTAAQKPQLLRHMEQH 988 HT + K FKC+ C + L+ H H Sbjct: 666 HTGE-KPFKCSECGKAFRAQSTLIHHQAIH 694 Score = 102 bits (253), Expect = 3e-21 Identities = 67/218 (30%), Positives = 99/218 (45%), Gaps = 11/218 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C K F K L H R HT EKPY C +C KA L H R+HTGEK + Sbjct: 222 KQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYK 281 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP-QDKK 383 C+ C T K L VH + +H K + C C K ++ NL +H + P Q K+ Sbjct: 282 CNECGKTFSDKSALLVH-KTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQCKE 340 Query: 384 VKEALDELCLMTREGK---RQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 + + R + + Y C +C++ F+++ +H+++H + P+ C CG Sbjct: 341 CDKVFSRKSYLERHRRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNECGKT 400 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + AL +H H Y C C K F L H Sbjct: 401 FGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARH 438 Score = 98.6 bits (244), Expect = 3e-20 Identities = 68/223 (30%), Positives = 97/223 (43%), Gaps = 12/223 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C KVF + +L H R+HT EKPY+C +C + K+ L H R HTGEK + Sbjct: 306 KPYKCNECGKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYK 365 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----Q 380 C C HL HI +H + K + C C K + + L+ H I P + Sbjct: 366 CKVCDKAFRHDSHLAQHIV-IHTREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNE 424 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 KV L R + Y C C++ F + +RH +H + P+ C++C Sbjct: 425 CGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKA 484 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 + L H H Y C C K FV + L H K +H Sbjct: 485 FRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMH-KVIH 526 Score = 97.1 bits (240), Expect = 1e-19 Identities = 70/223 (31%), Positives = 95/223 (42%), Gaps = 21/223 (9%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K +L H IHT EKPYKC +C ++NL H R HTGEK + Sbjct: 278 KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQ 337 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K +L+ H R+H K + C+ C K + +L +HI + K E Sbjct: 338 CKECDKVFSRKSYLERH-RRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNE 396 Query: 387 ALDELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 C T LL Y C+ C + F + + RH +H + P+ C+ Sbjct: 397 -----CGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCK 451 Query: 436 LCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 C ++ LE H R H Y C VC K F L H Sbjct: 452 ECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQH 494 Score = 93.2 bits (230), Expect = 1e-18 Identities = 67/229 (29%), Positives = 99/229 (43%), Gaps = 16/229 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C+K F+ L H IHT EKPYKC +C ++L +H HTGEK + Sbjct: 474 KPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYK 533 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + K L H R+H K + C C K + L H R + K +E Sbjct: 534 CNECGKSFNHKSSLAYH-HRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEE 592 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 L + R + Y C +C++ F + +H VH + P+ C++C Sbjct: 593 CDKVFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEKPYKCKVCDKA 652 Query: 441 ATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRLRTHIKEVHGAAQ 485 Y L H R H PF C+ C K F + L H + +HG + Sbjct: 653 FKCYSHLAQHTRIHTGEKPF--KCSECGKAFRAQSTL-IHHQAIHGVGK 698 Score = 92.8 bits (229), Expect = 2e-18 Identities = 68/224 (30%), Positives = 95/224 (42%), Gaps = 14/224 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C KVF + +L H R+HT EKPYKC +C + K++L H R HTGEK + Sbjct: 418 KPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYK 477 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDK---- 382 C C HL H +H K + C C K + +L+ H + H + + Sbjct: 478 CKVCDKAFRRDSHLAQHTV-IHTGEKPYKCNECGKTFVQNSSLVMH-KVIHTGEKRYKCN 535 Query: 383 ---KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 K L R + Y C+ C + F+ + H +H + P+ CE C Sbjct: 536 ECGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDK 595 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 LE+H R H Y C VC K F L H + VH Sbjct: 596 VFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQH-QRVH 638 Score = 91.7 bits (226), Expect = 4e-18 Identities = 68/228 (29%), Positives = 97/228 (42%), Gaps = 16/228 (7%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ K + C C K F +L H IHT EKPYKC +C ++NL H R HTGEK Sbjct: 387 TREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEK 446 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQD 381 + C C K HL+ H R+H K + C+ C K + +L +H I P Sbjct: 447 PYKCKECDKVFSRKSHLERH-RRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYK 505 Query: 382 KK------VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 V+ + + + G+++ Y C+ C + F ++ H +H + P+ C Sbjct: 506 CNECGKTFVQNSSLVMHKVIHTGEKR--YKCNECGKSFNHKSSLAYHHRLHTGEKPYKCN 563 Query: 436 LCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 CG L H R H Y C C K F L H + VH Sbjct: 564 ECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIH-RRVH 610 Score = 84.7 bits (208), Expect = 5e-16 Identities = 60/193 (31%), Positives = 82/193 (42%), Gaps = 27/193 (13%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F ++ H R HT E Y C++C T++ L H KC Sbjct: 533 KCNECGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKC-- 590 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + CD K L+ H +VHT ++ Y C VC+K+F D + H + + Sbjct: 591 EECDKVFNIKSHLEIHRRVHTG--EKPYKCRVCDKAFGRDSYLAQHQRVH---------- 638 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 G++ KC CD F K S L +H H G KPFKCS C A R++S Sbjct: 639 ------------TGEKPYKCKVCDKAF-KCYSHLAQHTRIHTGEKPFKCSECGKAFRAQS 685 Query: 923 NLKAHMNRHSTEK 935 L H H K Sbjct: 686 TLIHHQAIHGVGK 698 Score = 83.6 bits (205), Expect = 1e-15 Identities = 65/224 (29%), Positives = 89/224 (39%), Gaps = 14/224 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F K F + H IH EK YKC C K L H R HTGEK + Sbjct: 194 KSFQFNESGKSFNCSSLFKKHQIIHLGEKQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYM 253 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH--IRDAHDP----QD 381 C+ C K +L H R + C C K +SD L+ H I P + Sbjct: 254 CNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNEC 313 Query: 382 KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG--- 438 KV L R + Y C C++ F + +RH +H + P+ C++C Sbjct: 314 GKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYKCKVCDKAF 373 Query: 439 -HGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEVH 481 H + Q + +H R+ P Y C C K F + L H K +H Sbjct: 374 RHDSHLAQHIVIHTREKP--YKCNECGKTFGENSALLVH-KTIH 414 Score = 83.6 bits (205), Expect = 1e-15 Identities = 53/171 (30%), Positives = 71/171 (41%), Gaps = 20/171 (11%) Query: 897 QRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHK 956 ++H H G K +KC +C K L H H+ EK ++C+ CGK F K L H Sbjct: 212 KKHQIIHLGEKQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHY 271 Query: 957 LLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRK 1016 HT + K +KC C T + K LL H H KP++C C N +L RH+ Sbjct: 272 RRHTGE-KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHH--- 327 Query: 1017 HPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 V TGE +C C V+ K RH + G K Sbjct: 328 -------RVHTGEKP---------YQCKECDKVFSRKSYLERHRRIHTGEK 362 Score = 60.8 bits (146), Expect = 8e-09 Identities = 43/146 (29%), Positives = 56/146 (38%), Gaps = 10/146 (6%) Query: 931 HSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVS 990 H EK+ + GK F K H+++H + KQ+KC VC QK L H H Sbjct: 190 HRKEKSFQFNESGKSFNCSSLFKKHQIIHLGE-KQYKCDVCGKDFNQKRYLAHHRRCHTG 248 Query: 991 FKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG--GL 1041 KP+ C C N L RHY R + Y G+ L I G Sbjct: 249 EKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPY 308 Query: 1042 KCPVCSFVYGTKWEFNRHLKNKHGLK 1067 KC C V+ + RH + G K Sbjct: 309 KCNECGKVFNQQSNLARHHRVHTGEK 334 >gi|169214410 PREDICTED: similar to hCG1778601 isoform 1 [Homo sapiens] Length = 700 Score = 142 bits (359), Expect = 2e-33 Identities = 100/341 (29%), Positives = 148/341 (43%), Gaps = 23/341 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F Q + H R HT E Y C +C K+ L+RH KC Sbjct: 309 KCNECGKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYKCKV 368 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 CD + L H+ +HT ++ Y C C K+F E+ + H I T + Sbjct: 369 --CDKAFRHDSHLAQHIVIHTR--EKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNE 424 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V ++ L + G++ KC CD F + S L+RH H G KP+KC +C+ Sbjct: 425 CGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRK-SHLERHRRIHTGEKPYKCKVCDK 483 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A R S+L H H+ EK + C+ CGK F +L HK++HT + K++KC C + Sbjct: 484 AFRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGE-KRYKCNECGKSFN 542 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE---------EYANVGT 1027 K L H H KP++C C L H+ R H E + N+ + Sbjct: 543 HKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHH-RLHTGEKPYKCEECDKVFNIKS 601 Query: 1028 G-ELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 E+ V + KC VC +G +H + G K Sbjct: 602 HLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEK 642 Score = 135 bits (340), Expect = 2e-31 Identities = 92/302 (30%), Positives = 132/302 (43%), Gaps = 35/302 (11%) Query: 720 NSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSS 779 +SL KK L E+ K C+ CGK F + + H R HT E Y C++C Sbjct: 208 SSLFKKHQIIHLGEKQYK------CDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVF 261 Query: 780 ITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSF 839 K L RH + KC + C + DK L H +HT ++ Y C C K F Sbjct: 262 NKKAYLARHYRRHTGEKPYKC--NECGKTFSDKSALLVHKTIHTG--EKPYKCNECGKVF 317 Query: 840 SEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRH 899 ++ + H + + G++ +C CD F + S L+RH Sbjct: 318 NQQSNLARHHRVH----------------------TGEKPYQCKECDKVFSRK-SYLERH 354 Query: 900 IWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLH 959 H G KP+KC +C+ A R S+L H+ H+ EK + C+ CGK F L HK +H Sbjct: 355 RRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNECGKTFGENSALLVHKTIH 414 Query: 960 TADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPN 1019 T + K +KC C Q+ L RH H KP++C C + L+RH R H Sbjct: 415 TGE-KPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERH-RRIHTG 472 Query: 1020 EE 1021 E+ Sbjct: 473 EK 474 Score = 131 bits (330), Expect = 3e-30 Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 47/366 (12%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK+F + + H R HT E Y C++C + K+ L H KC Sbjct: 254 CNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNEC 313 Query: 804 G--------------------------CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEK 837 G CD K L+ H ++HT ++ Y C VC+K Sbjct: 314 GKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTG--EKPYKCKVCDK 371 Query: 838 SFSEDRLIKSHIKTNHPEVSM------STISEVLGRRVQLKGLIGKRAMKCPYCDFYFMK 891 +F D + HI + E T E V G++ KC C F + Sbjct: 372 AFRHDSHLAQHIVIHTREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQ 431 Query: 892 NGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGT 951 S+L RH H G KP+KC C+ KS+L+ H H+ EK + C +C K F+ Sbjct: 432 Q-SNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSH 490 Query: 952 LKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKR 1011 L H ++HT + K +KC C T Q L+ H H K ++C C S N SL Sbjct: 491 LAQHTVIHTGE-KPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAY 549 Query: 1012 HYNRKHPNEEYANVG--------TGELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLK 1061 H+ R H E+ +LA + G KC C V+ K H + Sbjct: 550 HH-RLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRR 608 Query: 1062 NKHGLK 1067 G K Sbjct: 609 VHTGEK 614 Score = 123 bits (308), Expect = 1e-27 Identities = 81/276 (29%), Positives = 118/276 (42%), Gaps = 12/276 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F Q + H R HT E Y C +C K+ L+RH KC Sbjct: 421 KCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKV 480 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 CD + L H +HT ++ Y C C K+F ++ + H I T + Sbjct: 481 --CDKAFRRDSHLAQHTVIHTG--EKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNE 536 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + + L + G++ KC C F + S L H H G KP+KC C+ Sbjct: 537 CGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVF-RTQSQLACHHRLHTGEKPYKCEECDK 595 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 KS+L+ H H+ EK + C +C K F L H+ +HT + K +KC VCD Sbjct: 596 VFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGE-KPYKCKVCDKAFK 654 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L +H H KPF+C+ C + +L H Sbjct: 655 CYSHLAQHTRIHTGEKPFKCSECGKAFRAQSTLIHH 690 Score = 110 bits (274), Expect = 1e-23 Identities = 76/270 (28%), Positives = 114/270 (42%), Gaps = 12/270 (4%) Query: 725 KQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNC 784 +Q N + R+ +C+ C K+F + H + H R HT E Y C C + + Sbjct: 431 QQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSH 490 Query: 785 LKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRL 844 L +H + KC + C + L H +HT ++ Y C C KSF+ Sbjct: 491 LAQHTVIHTGEKPYKC--NECGKTFVQNSSLVMHKVIHTG--EKRYKCNECGKSFNHKSS 546 Query: 845 IKSH--IKTNHPEVSMSTISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQR 898 + H + T + +V + QL + G++ KC CD F S L+ Sbjct: 547 LAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIK-SHLEI 605 Query: 899 HIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLL 958 H H G KP+KC +C+ A S L H H+ EK + C +C K FK L H + Sbjct: 606 HRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEKPYKCKVCDKAFKCYSHLAQHTRI 665 Query: 959 HTADGKQFKCTVCDYTAAQKPQLLRHMEQH 988 HT + K FKC+ C + L+ H H Sbjct: 666 HTGE-KPFKCSECGKAFRAQSTLIHHQAIH 694 Score = 102 bits (253), Expect = 3e-21 Identities = 67/218 (30%), Positives = 99/218 (45%), Gaps = 11/218 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C K F K L H R HT EKPY C +C KA L H R+HTGEK + Sbjct: 222 KQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYK 281 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP-QDKK 383 C+ C T K L VH + +H K + C C K ++ NL +H + P Q K+ Sbjct: 282 CNECGKTFSDKSALLVH-KTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQCKE 340 Query: 384 VKEALDELCLMTREGK---RQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 + + R + + Y C +C++ F+++ +H+++H + P+ C CG Sbjct: 341 CDKVFSRKSYLERHRRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNECGKT 400 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + AL +H H Y C C K F L H Sbjct: 401 FGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARH 438 Score = 98.6 bits (244), Expect = 3e-20 Identities = 68/223 (30%), Positives = 97/223 (43%), Gaps = 12/223 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C KVF + +L H R+HT EKPY+C +C + K+ L H R HTGEK + Sbjct: 306 KPYKCNECGKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYK 365 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----Q 380 C C HL HI +H + K + C C K + + L+ H I P + Sbjct: 366 CKVCDKAFRHDSHLAQHIV-IHTREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNE 424 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 KV L R + Y C C++ F + +RH +H + P+ C++C Sbjct: 425 CGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKA 484 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 + L H H Y C C K FV + L H K +H Sbjct: 485 FRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMH-KVIH 526 Score = 97.1 bits (240), Expect = 1e-19 Identities = 70/223 (31%), Positives = 95/223 (42%), Gaps = 21/223 (9%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K +L H IHT EKPYKC +C ++NL H R HTGEK + Sbjct: 278 KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQ 337 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K +L+ H R+H K + C+ C K + +L +HI + K E Sbjct: 338 CKECDKVFSRKSYLERH-RRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNE 396 Query: 387 ALDELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 C T LL Y C+ C + F + + RH +H + P+ C+ Sbjct: 397 -----CGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCK 451 Query: 436 LCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 C ++ LE H R H Y C VC K F L H Sbjct: 452 ECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQH 494 Score = 93.2 bits (230), Expect = 1e-18 Identities = 67/229 (29%), Positives = 99/229 (43%), Gaps = 16/229 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C+K F+ L H IHT EKPYKC +C ++L +H HTGEK + Sbjct: 474 KPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYK 533 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + K L H R+H K + C C K + L H R + K +E Sbjct: 534 CNECGKSFNHKSSLAYH-HRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEE 592 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 L + R + Y C +C++ F + +H VH + P+ C++C Sbjct: 593 CDKVFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEKPYKCKVCDKA 652 Query: 441 ATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRLRTHIKEVHGAAQ 485 Y L H R H PF C+ C K F + L H + +HG + Sbjct: 653 FKCYSHLAQHTRIHTGEKPF--KCSECGKAFRAQSTL-IHHQAIHGVGK 698 Score = 92.8 bits (229), Expect = 2e-18 Identities = 68/224 (30%), Positives = 95/224 (42%), Gaps = 14/224 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C KVF + +L H R+HT EKPYKC +C + K++L H R HTGEK + Sbjct: 418 KPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYK 477 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDK---- 382 C C HL H +H K + C C K + +L+ H + H + + Sbjct: 478 CKVCDKAFRRDSHLAQHTV-IHTGEKPYKCNECGKTFVQNSSLVMH-KVIHTGEKRYKCN 535 Query: 383 ---KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 K L R + Y C+ C + F+ + H +H + P+ CE C Sbjct: 536 ECGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDK 595 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 LE+H R H Y C VC K F L H + VH Sbjct: 596 VFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQH-QRVH 638 Score = 91.7 bits (226), Expect = 4e-18 Identities = 68/228 (29%), Positives = 97/228 (42%), Gaps = 16/228 (7%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ K + C C K F +L H IHT EKPYKC +C ++NL H R HTGEK Sbjct: 387 TREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEK 446 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQD 381 + C C K HL+ H R+H K + C+ C K + +L +H I P Sbjct: 447 PYKCKECDKVFSRKSHLERH-RRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYK 505 Query: 382 KK------VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 V+ + + + G+++ Y C+ C + F ++ H +H + P+ C Sbjct: 506 CNECGKTFVQNSSLVMHKVIHTGEKR--YKCNECGKSFNHKSSLAYHHRLHTGEKPYKCN 563 Query: 436 LCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 CG L H R H Y C C K F L H + VH Sbjct: 564 ECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIH-RRVH 610 Score = 84.7 bits (208), Expect = 5e-16 Identities = 60/193 (31%), Positives = 82/193 (42%), Gaps = 27/193 (13%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F ++ H R HT E Y C++C T++ L H KC Sbjct: 533 KCNECGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKC-- 590 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + CD K L+ H +VHT ++ Y C VC+K+F D + H + + Sbjct: 591 EECDKVFNIKSHLEIHRRVHTG--EKPYKCRVCDKAFGRDSYLAQHQRVH---------- 638 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 G++ KC CD F K S L +H H G KPFKCS C A R++S Sbjct: 639 ------------TGEKPYKCKVCDKAF-KCYSHLAQHTRIHTGEKPFKCSECGKAFRAQS 685 Query: 923 NLKAHMNRHSTEK 935 L H H K Sbjct: 686 TLIHHQAIHGVGK 698 Score = 83.6 bits (205), Expect = 1e-15 Identities = 65/224 (29%), Positives = 89/224 (39%), Gaps = 14/224 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F K F + H IH EK YKC C K L H R HTGEK + Sbjct: 194 KSFQFNESGKSFNCSSLFKKHQIIHLGEKQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYM 253 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH--IRDAHDP----QD 381 C+ C K +L H R + C C K +SD L+ H I P + Sbjct: 254 CNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNEC 313 Query: 382 KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG--- 438 KV L R + Y C C++ F + +RH +H + P+ C++C Sbjct: 314 GKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYKCKVCDKAF 373 Query: 439 -HGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEVH 481 H + Q + +H R+ P Y C C K F + L H K +H Sbjct: 374 RHDSHLAQHIVIHTREKP--YKCNECGKTFGENSALLVH-KTIH 414 Score = 83.6 bits (205), Expect = 1e-15 Identities = 53/171 (30%), Positives = 71/171 (41%), Gaps = 20/171 (11%) Query: 897 QRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHK 956 ++H H G K +KC +C K L H H+ EK ++C+ CGK F K L H Sbjct: 212 KKHQIIHLGEKQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHY 271 Query: 957 LLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRK 1016 HT + K +KC C T + K LL H H KP++C C N +L RH+ Sbjct: 272 RRHTGE-KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHH--- 327 Query: 1017 HPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 V TGE +C C V+ K RH + G K Sbjct: 328 -------RVHTGEKP---------YQCKECDKVFSRKSYLERHRRIHTGEK 362 Score = 60.8 bits (146), Expect = 8e-09 Identities = 43/146 (29%), Positives = 56/146 (38%), Gaps = 10/146 (6%) Query: 931 HSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVS 990 H EK+ + GK F K H+++H + KQ+KC VC QK L H H Sbjct: 190 HRKEKSFQFNESGKSFNCSSLFKKHQIIHLGE-KQYKCDVCGKDFNQKRYLAHHRRCHTG 248 Query: 991 FKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG--GL 1041 KP+ C C N L RHY R + Y G+ L I G Sbjct: 249 EKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPY 308 Query: 1042 KCPVCSFVYGTKWEFNRHLKNKHGLK 1067 KC C V+ + RH + G K Sbjct: 309 KCNECGKVFNQQSNLARHHRVHTGEK 334 >gi|169213416 PREDICTED: hypothetical protein LOC388559 [Homo sapiens] Length = 700 Score = 142 bits (359), Expect = 2e-33 Identities = 100/341 (29%), Positives = 148/341 (43%), Gaps = 23/341 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F Q + H R HT E Y C +C K+ L+RH KC Sbjct: 309 KCNECGKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYKCKV 368 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 CD + L H+ +HT ++ Y C C K+F E+ + H I T + Sbjct: 369 --CDKAFRHDSHLAQHIVIHTR--EKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNE 424 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V ++ L + G++ KC CD F + S L+RH H G KP+KC +C+ Sbjct: 425 CGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRK-SHLERHRRIHTGEKPYKCKVCDK 483 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A R S+L H H+ EK + C+ CGK F +L HK++HT + K++KC C + Sbjct: 484 AFRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGE-KRYKCNECGKSFN 542 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE---------EYANVGT 1027 K L H H KP++C C L H+ R H E + N+ + Sbjct: 543 HKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHH-RLHTGEKPYKCEECDKVFNIKS 601 Query: 1028 G-ELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 E+ V + KC VC +G +H + G K Sbjct: 602 HLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEK 642 Score = 135 bits (340), Expect = 2e-31 Identities = 92/302 (30%), Positives = 132/302 (43%), Gaps = 35/302 (11%) Query: 720 NSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSS 779 +SL KK L E+ K C+ CGK F + + H R HT E Y C++C Sbjct: 208 SSLFKKHQIIHLGEKQYK------CDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVF 261 Query: 780 ITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSF 839 K L RH + KC + C + DK L H +HT ++ Y C C K F Sbjct: 262 NKKAYLARHYRRHTGEKPYKC--NECGKTFSDKSALLVHKTIHTG--EKPYKCNECGKVF 317 Query: 840 SEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRH 899 ++ + H + + G++ +C CD F + S L+RH Sbjct: 318 NQQSNLARHHRVH----------------------TGEKPYQCKECDKVFSRK-SYLERH 354 Query: 900 IWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLH 959 H G KP+KC +C+ A R S+L H+ H+ EK + C+ CGK F L HK +H Sbjct: 355 RRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNECGKTFGENSALLVHKTIH 414 Query: 960 TADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPN 1019 T + K +KC C Q+ L RH H KP++C C + L+RH R H Sbjct: 415 TGE-KPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERH-RRIHTG 472 Query: 1020 EE 1021 E+ Sbjct: 473 EK 474 Score = 131 bits (330), Expect = 3e-30 Identities = 101/366 (27%), Positives = 142/366 (38%), Gaps = 47/366 (12%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK+F + + H R HT E Y C++C + K+ L H KC Sbjct: 254 CNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNEC 313 Query: 804 G--------------------------CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEK 837 G CD K L+ H ++HT ++ Y C VC+K Sbjct: 314 GKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTG--EKPYKCKVCDK 371 Query: 838 SFSEDRLIKSHIKTNHPEVSM------STISEVLGRRVQLKGLIGKRAMKCPYCDFYFMK 891 +F D + HI + E T E V G++ KC C F + Sbjct: 372 AFRHDSHLAQHIVIHTREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQ 431 Query: 892 NGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGT 951 S+L RH H G KP+KC C+ KS+L+ H H+ EK + C +C K F+ Sbjct: 432 Q-SNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSH 490 Query: 952 LKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKR 1011 L H ++HT + K +KC C T Q L+ H H K ++C C S N SL Sbjct: 491 LAQHTVIHTGE-KPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNECGKSFNHKSSLAY 549 Query: 1012 HYNRKHPNEEYANVG--------TGELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLK 1061 H+ R H E+ +LA + G KC C V+ K H + Sbjct: 550 HH-RLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIHRR 608 Query: 1062 NKHGLK 1067 G K Sbjct: 609 VHTGEK 614 Score = 123 bits (308), Expect = 1e-27 Identities = 81/276 (29%), Positives = 118/276 (42%), Gaps = 12/276 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK+F Q + H R HT E Y C +C K+ L+RH KC Sbjct: 421 KCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKV 480 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 CD + L H +HT ++ Y C C K+F ++ + H I T + Sbjct: 481 --CDKAFRRDSHLAQHTVIHTG--EKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYKCNE 536 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + + L + G++ KC C F + S L H H G KP+KC C+ Sbjct: 537 CGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVF-RTQSQLACHHRLHTGEKPYKCEECDK 595 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 KS+L+ H H+ EK + C +C K F L H+ +HT + K +KC VCD Sbjct: 596 VFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGE-KPYKCKVCDKAFK 654 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L +H H KPF+C+ C + +L H Sbjct: 655 CYSHLAQHTRIHTGEKPFKCSECGKAFRAQSTLIHH 690 Score = 110 bits (274), Expect = 1e-23 Identities = 76/270 (28%), Positives = 114/270 (42%), Gaps = 12/270 (4%) Query: 725 KQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNC 784 +Q N + R+ +C+ C K+F + H + H R HT E Y C C + + Sbjct: 431 QQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSH 490 Query: 785 LKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRL 844 L +H + KC + C + L H +HT ++ Y C C KSF+ Sbjct: 491 LAQHTVIHTGEKPYKC--NECGKTFVQNSSLVMHKVIHTG--EKRYKCNECGKSFNHKSS 546 Query: 845 IKSH--IKTNHPEVSMSTISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQR 898 + H + T + +V + QL + G++ KC CD F S L+ Sbjct: 547 LAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIK-SHLEI 605 Query: 899 HIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLL 958 H H G KP+KC +C+ A S L H H+ EK + C +C K FK L H + Sbjct: 606 HRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEKPYKCKVCDKAFKCYSHLAQHTRI 665 Query: 959 HTADGKQFKCTVCDYTAAQKPQLLRHMEQH 988 HT + K FKC+ C + L+ H H Sbjct: 666 HTGE-KPFKCSECGKAFRAQSTLIHHQAIH 694 Score = 102 bits (253), Expect = 3e-21 Identities = 67/218 (30%), Positives = 99/218 (45%), Gaps = 11/218 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C K F K L H R HT EKPY C +C KA L H R+HTGEK + Sbjct: 222 KQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYK 281 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP-QDKK 383 C+ C T K L VH + +H K + C C K ++ NL +H + P Q K+ Sbjct: 282 CNECGKTFSDKSALLVH-KTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQCKE 340 Query: 384 VKEALDELCLMTREGK---RQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 + + R + + Y C +C++ F+++ +H+++H + P+ C CG Sbjct: 341 CDKVFSRKSYLERHRRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNECGKT 400 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + AL +H H Y C C K F L H Sbjct: 401 FGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARH 438 Score = 98.6 bits (244), Expect = 3e-20 Identities = 68/223 (30%), Positives = 97/223 (43%), Gaps = 12/223 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C KVF + +L H R+HT EKPY+C +C + K+ L H R HTGEK + Sbjct: 306 KPYKCNECGKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYK 365 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----Q 380 C C HL HI +H + K + C C K + + L+ H I P + Sbjct: 366 CKVCDKAFRHDSHLAQHIV-IHTREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNE 424 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 KV L R + Y C C++ F + +RH +H + P+ C++C Sbjct: 425 CGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKA 484 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 + L H H Y C C K FV + L H K +H Sbjct: 485 FRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMH-KVIH 526 Score = 97.1 bits (240), Expect = 1e-19 Identities = 70/223 (31%), Positives = 95/223 (42%), Gaps = 21/223 (9%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K +L H IHT EKPYKC +C ++NL H R HTGEK + Sbjct: 278 KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRVHTGEKPYQ 337 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K +L+ H R+H K + C+ C K + +L +HI + K E Sbjct: 338 CKECDKVFSRKSYLERH-RRIHTGEKPYKCKVCDKAFRHDSHLAQHIVIHTREKPYKCNE 396 Query: 387 ALDELCLMTREGKRQLL-----------YDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 C T LL Y C+ C + F + + RH +H + P+ C+ Sbjct: 397 -----CGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCK 451 Query: 436 LCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 C ++ LE H R H Y C VC K F L H Sbjct: 452 ECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRRDSHLAQH 494 Score = 93.2 bits (230), Expect = 1e-18 Identities = 67/229 (29%), Positives = 99/229 (43%), Gaps = 16/229 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C+K F+ L H IHT EKPYKC +C ++L +H HTGEK + Sbjct: 474 KPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYKCNECGKTFVQNSSLVMHKVIHTGEKRYK 533 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + K L H R+H K + C C K + L H R + K +E Sbjct: 534 CNECGKSFNHKSSLAYH-HRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEE 592 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 L + R + Y C +C++ F + +H VH + P+ C++C Sbjct: 593 CDKVFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQHQRVHTGEKPYKCKVCDKA 652 Query: 441 ATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRLRTHIKEVHGAAQ 485 Y L H R H PF C+ C K F + L H + +HG + Sbjct: 653 FKCYSHLAQHTRIHTGEKPF--KCSECGKAFRAQSTL-IHHQAIHGVGK 698 Score = 92.8 bits (229), Expect = 2e-18 Identities = 68/224 (30%), Positives = 95/224 (42%), Gaps = 14/224 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C KVF + +L H R+HT EKPYKC +C + K++L H R HTGEK + Sbjct: 418 KPYKCNECGKVFNQQSNLARHHRLHTGEKPYKCKECDKVFSRKSHLERHRRIHTGEKPYK 477 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDK---- 382 C C HL H +H K + C C K + +L+ H + H + + Sbjct: 478 CKVCDKAFRRDSHLAQHTV-IHTGEKPYKCNECGKTFVQNSSLVMH-KVIHTGEKRYKCN 535 Query: 383 ---KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 K L R + Y C+ C + F+ + H +H + P+ CE C Sbjct: 536 ECGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKCEECDK 595 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 LE+H R H Y C VC K F L H + VH Sbjct: 596 VFNIKSHLEIHRRVHTGEKPYKCRVCDKAFGRDSYLAQH-QRVH 638 Score = 91.7 bits (226), Expect = 4e-18 Identities = 68/228 (29%), Positives = 97/228 (42%), Gaps = 16/228 (7%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ K + C C K F +L H IHT EKPYKC +C ++NL H R HTGEK Sbjct: 387 TREKPYKCNECGKTFGENSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHHRLHTGEK 446 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQD 381 + C C K HL+ H R+H K + C+ C K + +L +H I P Sbjct: 447 PYKCKECDKVFSRKSHLERH-RRIHTGEKPYKCKVCDKAFRRDSHLAQHTVIHTGEKPYK 505 Query: 382 KK------VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 V+ + + + G+++ Y C+ C + F ++ H +H + P+ C Sbjct: 506 CNECGKTFVQNSSLVMHKVIHTGEKR--YKCNECGKSFNHKSSLAYHHRLHTGEKPYKCN 563 Query: 436 LCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 CG L H R H Y C C K F L H + VH Sbjct: 564 ECGKVFRTQSQLACHHRLHTGEKPYKCEECDKVFNIKSHLEIH-RRVH 610 Score = 84.7 bits (208), Expect = 5e-16 Identities = 60/193 (31%), Positives = 82/193 (42%), Gaps = 27/193 (13%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F ++ H R HT E Y C++C T++ L H KC Sbjct: 533 KCNECGKSFNHKSSLAYHHRLHTGEKPYKCNECGKVFRTQSQLACHHRLHTGEKPYKC-- 590 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + CD K L+ H +VHT ++ Y C VC+K+F D + H + + Sbjct: 591 EECDKVFNIKSHLEIHRRVHTG--EKPYKCRVCDKAFGRDSYLAQHQRVH---------- 638 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 G++ KC CD F K S L +H H G KPFKCS C A R++S Sbjct: 639 ------------TGEKPYKCKVCDKAF-KCYSHLAQHTRIHTGEKPFKCSECGKAFRAQS 685 Query: 923 NLKAHMNRHSTEK 935 L H H K Sbjct: 686 TLIHHQAIHGVGK 698 Score = 83.6 bits (205), Expect = 1e-15 Identities = 65/224 (29%), Positives = 89/224 (39%), Gaps = 14/224 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F K F + H IH EK YKC C K L H R HTGEK + Sbjct: 194 KSFQFNESGKSFNCSSLFKKHQIIHLGEKQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYM 253 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH--IRDAHDP----QD 381 C+ C K +L H R + C C K +SD L+ H I P + Sbjct: 254 CNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNEC 313 Query: 382 KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG--- 438 KV L R + Y C C++ F + +RH +H + P+ C++C Sbjct: 314 GKVFNQQSNLARHHRVHTGEKPYQCKECDKVFSRKSYLERHRRIHTGEKPYKCKVCDKAF 373 Query: 439 -HGATKYQALELHVRKHPFVYVCAVCRKKFVSSIRLRTHIKEVH 481 H + Q + +H R+ P Y C C K F + L H K +H Sbjct: 374 RHDSHLAQHIVIHTREKP--YKCNECGKTFGENSALLVH-KTIH 414 Score = 83.6 bits (205), Expect = 1e-15 Identities = 53/171 (30%), Positives = 71/171 (41%), Gaps = 20/171 (11%) Query: 897 QRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHK 956 ++H H G K +KC +C K L H H+ EK ++C+ CGK F K L H Sbjct: 212 KKHQIIHLGEKQYKCDVCGKDFNQKRYLAHHRRCHTGEKPYMCNKCGKVFNKKAYLARHY 271 Query: 957 LLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRK 1016 HT + K +KC C T + K LL H H KP++C C N +L RH+ Sbjct: 272 RRHTGE-KPYKCNECGKTFSDKSALLVHKTIHTGEKPYKCNECGKVFNQQSNLARHH--- 327 Query: 1017 HPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 V TGE +C C V+ K RH + G K Sbjct: 328 -------RVHTGEKP---------YQCKECDKVFSRKSYLERHRRIHTGEK 362 Score = 60.8 bits (146), Expect = 8e-09 Identities = 43/146 (29%), Positives = 56/146 (38%), Gaps = 10/146 (6%) Query: 931 HSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVS 990 H EK+ + GK F K H+++H + KQ+KC VC QK L H H Sbjct: 190 HRKEKSFQFNESGKSFNCSSLFKKHQIIHLGE-KQYKCDVCGKDFNQKRYLAHHRRCHTG 248 Query: 991 FKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG--GL 1041 KP+ C C N L RHY R + Y G+ L I G Sbjct: 249 EKPYMCNKCGKVFNKKAYLARHYRRHTGEKPYKCNECGKTFSDKSALLVHKTIHTGEKPY 308 Query: 1042 KCPVCSFVYGTKWEFNRHLKNKHGLK 1067 KC C V+ + RH + G K Sbjct: 309 KCNECGKVFNQQSNLARHHRVHTGEK 334 >gi|72384365 zinc finger protein 816A [Homo sapiens] Length = 651 Score = 141 bits (355), Expect = 4e-33 Identities = 88/276 (31%), Positives = 125/276 (45%), Gaps = 12/276 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F + H HT E Y C +C I ++ L+RH KC Sbjct: 370 KCNECGKTFSQKSSLQCHHILHTGEKPYKCEECDNVYIRRSHLERHRKIHTGEGSYKCKV 429 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 CD L H +VHT ++ Y C C +SFS ++ H + T + + Sbjct: 430 --CDKVFRSDSYLAEHQRVHTG--EKPYKCNKCGRSFSRKSSLQYHHTLHTGEKPYTCNE 485 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V RR L + G++ KC CD F + S L+RH H G KP+KC +C+ Sbjct: 486 CGKVFSRRENLARHHRLHAGEKPYKCEECDKVFSRR-SHLERHRRIHTGEKPYKCKVCDK 544 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A RS S L H H+ EK + C+ C K F KG L H+ +HT + K +KC C Sbjct: 545 AFRSDSCLANHTRVHTGEKPYKCNKCAKVFNQKGILAQHQRVHTGE-KPYKCNECGKVFN 603 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 QK L +H H + KP++C C + +L H Sbjct: 604 QKASLAKHQRVHTAEKPYKCNECGKAFTGQSTLIHH 639 Score = 120 bits (302), Expect = 6e-27 Identities = 122/510 (23%), Positives = 189/510 (37%), Gaps = 60/510 (11%) Query: 577 LETTVVSSSDLHS--QEVVSDDFLLKNDTSSAEAHAAPEKPPDMQHRS----SVQTQGEV 630 L++ + SS HS EV+ L ++ + PE D+ H V+ G Sbjct: 67 LKSMMEFSSTRHSITGEVIHTGTLQRHKSHHIGDFCFPEMKKDIHHFEFQWQEVERNGHE 126 Query: 631 ITLLLSKAQSAGSDQESH--GAQSPLGEGQNMAVLSAGDPDPSRCLRSNPAEASDLLPPV 688 + K + +D+ H P+ ++ LS P + + S+ L Sbjct: 127 APMTKIKKLTGSTDRSDHRHAGNKPI---KDQLGLSFHSHLPELHMFQTKGKISNQLDKS 183 Query: 689 AGGGDTITHQPDSCKAAPEHRSGITAFMKVLNSLQKKQMNTSLCERIRKVYGDLECEY-- 746 G Q SC+ + N K +++S + + C+ Sbjct: 184 IGASSASESQRISCRLKTH----------ISNKYGKNFLHSSFTQIQEICMREKPCQSNE 233 Query: 747 CGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCD 806 CGK F Y H TH+RE Y C C K + H KC + C Sbjct: 234 CGKAFNYSSLLRRHHITHSREREYKCDVCGKIFNQKQYIVYHHRCHTGEKTYKC--NECG 291 Query: 807 YSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLG 866 + L H ++HT ++ Y C C K+FSE ++ H Sbjct: 292 KTFTQMSSLVCHRRLHTG--EKPYKCNECGKTFSEKSSLRCH------------------ 331 Query: 867 RRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKA 926 RR+ G++ KC C F +N S L H H G KP+KC+ C KS+L+ Sbjct: 332 RRLHT----GEKPYKCNECGKTFGRN-SALVIHKAIHTGEKPYKCNECGKTFSQKSSLQC 386 Query: 927 HMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHME 986 H H+ EK + C+ C + + L+ H+ +HT +G +KC VCD L H Sbjct: 387 HHILHTGEKPYKCEECDNVYIRRSHLERHRKIHTGEGS-YKCKVCDKVFRSDSYLAEHQR 445 Query: 987 QHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLIQQG 1039 H KP++C C S + SL+ H+ + Y G+ LA + G Sbjct: 446 VHTGEKPYKCNKCGRSFSRKSSLQYHHTLHTGEKPYTCNECGKVFSRRENLARHHRLHAG 505 Query: 1040 --GLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 KC C V+ + RH + G K Sbjct: 506 EKPYKCEECDKVFSRRSHLERHRRIHTGEK 535 Score = 102 bits (254), Expect = 2e-21 Identities = 69/258 (26%), Positives = 108/258 (41%), Gaps = 58/258 (22%) Query: 733 ERIRKVY---GDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRH- 788 ER RK++ G +C+ C K+F + H R HT E Y C++C S K+ L+ H Sbjct: 413 ERHRKIHTGEGSYKCKVCDKVFRSDSYLAEHQRVHTGEKPYKCNKCGRSFSRKSSLQYHH 472 Query: 789 ----------------VIQKHSNIL-----------LKCPTDGCDYSTPDKYKLQAHLKV 821 V + N+ KC + CD + L+ H ++ Sbjct: 473 TLHTGEKPYTCNECGKVFSRRENLARHHRLHAGEKPYKC--EECDKVFSRRSHLERHRRI 530 Query: 822 HTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMK 881 HT ++ Y C VC+K+F D + +H + + G++ K Sbjct: 531 HTG--EKPYKCKVCDKAFRSDSCLANHTRVH----------------------TGEKPYK 566 Query: 882 CPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDM 941 C C F + G L +H H G KP+KC+ C K++L H H+ EK + C+ Sbjct: 567 CNKCAKVFNQKGI-LAQHQRVHTGEKPYKCNECGKVFNQKASLAKHQRVHTAEKPYKCNE 625 Query: 942 CGKKFKSKGTLKSHKLLH 959 CGK F + TL H+ +H Sbjct: 626 CGKAFTGQSTLIHHQAIH 643 Score = 99.8 bits (247), Expect = 1e-20 Identities = 65/219 (29%), Positives = 96/219 (43%), Gaps = 13/219 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F SL H R+HT EKPYKC +C + K++L H R HTGEK + Sbjct: 283 KTYKCNECGKTFTQMSSLVCHRRLHTGEKPYKCNECGKTFSEKSSLRCHRRLHTGEKPYK 342 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C T L +H + +H K + C C K +S +L H H + E Sbjct: 343 CNECGKTFGRNSALVIH-KAIHTGEKPYKCNECGKTFSQKSSLQCH-HILHTGEKPYKCE 400 Query: 387 ALDELCLMTREGKR-------QLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 D + + +R + Y C +C++ F+++ H VH + P+ C CG Sbjct: 401 ECDNVYIRRSHLERHRKIHTGEGSYKCKVCDKVFRSDSYLAEHQRVHTGEKPYKCNKCGR 460 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 ++ +L+ H H Y C C K F L H Sbjct: 461 SFSRKSSLQYHHTLHTGEKPYTCNECGKVFSRRENLARH 499 Score = 93.2 bits (230), Expect = 1e-18 Identities = 64/221 (28%), Positives = 90/221 (40%), Gaps = 28/221 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C + F K SLQ H +HT EKPY C +C + + NL H R H GEK + Sbjct: 451 KPYKCNKCGRSFSRKSSLQYHHTLHTGEKPYTCNECGKVFSRRENLARHHRLHAGEKPYK 510 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + HL+ H R+H K + C+ C K + L H Sbjct: 511 CEECDKVFSRRSHLERH-RRIHTGEKPYKCKVCDKAFRSDSCLANH-------------- 555 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 TR + Y C+ C + F + +H VH + P+ C CG + + Sbjct: 556 --------TRVHTGEKPYKCNKCAKVFNQKGILAQHQRVHTGEKPYKCNECGKVFNQKAS 607 Query: 447 LELHVRKHPF--VYVCAVCRKKFVSSIRLRTHIKEVHGAAQ 485 L H R H Y C C K F L H + +HG + Sbjct: 608 LAKHQRVHTAEKPYKCNECGKAFTGQSTL-IHHQAIHGCRE 647 Score = 89.7 bits (221), Expect = 2e-17 Identities = 65/234 (27%), Positives = 96/234 (41%), Gaps = 32/234 (13%) Query: 254 YEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKAN 313 Y ++ + ++ + + C+ C K+F K + H R HT EK YKC +C ++ Sbjct: 240 YSSLLRRHHITHSREREYKCDVCGKIFNQKQYIVYHHRCHTGEKTYKCNECGKTFTQMSS 299 Query: 314 LNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIK 371 L H R HTGEK + C+ C T K L+ H R+H K + C C K + L+ Sbjct: 300 LVCHRRLHTGEKPYKCNECGKTFSEKSSLRCH-RRLHTGEKPYKCNECGKTFGRNSALVI 358 Query: 372 H--IRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDK 429 H I P Y C+ C + F + H ++H + Sbjct: 359 HKAIHTGEKP------------------------YKCNECGKTFSQKSSLQCHHILHTGE 394 Query: 430 WPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 P+ CE C + + LE H + H Y C VC K F S L H + VH Sbjct: 395 KPYKCEECDNVYIRRSHLERHRKIHTGEGSYKCKVCDKVFRSDSYLAEH-QRVH 447 >gi|167234429 zinc finger and BTB domain containing 17 [Homo sapiens] Length = 803 Score = 140 bits (353), Expect = 8e-33 Identities = 138/572 (24%), Positives = 227/572 (39%), Gaps = 71/572 (12%) Query: 484 AQEALVFTSSINQSFCLLEPGGDIQQEALGDQLQLVEEEFALQGVNALKEEACPGDTQLE 543 A+E V TS++++ LE G + +G L EE +G A + T+ Sbjct: 137 AKEEKVATSTLSR----LEQAG--RSTPIGPSRDLKEE----RGGQAQSAASGAEQTEKA 186 Query: 544 EGRKEPEAPGEMPAPAVHLASPQAESTALPPCELETTVVSSSDLHSQEVVSDDFLLKNDT 603 + +EP P P +A+ +AE+ E E V + ++ K Sbjct: 187 DAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEEQ--------KEQE 238 Query: 604 SSAEAHAAPEKPPDMQHRSSVQTQGEVITLLLSKAQSAGSDQESHGAQSPLGEGQNMAVL 663 E A P +++ S GE A ++ES G S GQ + Sbjct: 239 EQEEEGAGPA---EVKEEGSQLENGE--------APEENENEESAGTDS----GQELG-- 281 Query: 664 SAGDPDPSRCLRSNPAEASDLLPPVAGGGDTITHQPDSCKAAPEHRSGITAFMKV----- 718 +R LRS D A G ++ H+ + C H +++ Sbjct: 282 -----SEARGLRSGTY--GDRTESKAYG--SVIHKCEDCGKEFTHTGNFKRHIRIHTGEK 332 Query: 719 ---LNSLQKKQMNTSLCERIRKVYGDLE---CEYCGKLFWYQVHFDMHVRTHTREHLYYC 772 K + + C+ K + L+ CE CGK + ++H + H+ E Y C Sbjct: 333 PFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRC 392 Query: 773 SQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSC 832 C T LKRH + +C D C S D HL+ H + + C Sbjct: 393 EDCGKLFTTSGNLKRHQLVHSGEKPYQC--DYCGRSFSDPTSKMRHLETHDT--DKEHKC 448 Query: 833 PVCEKSFSEDRLIKSHIKTNHPEVSMS--------TISEVLGRRVQLKGLIGKRAMKCPY 884 P C+K F++ +K+H+K + + + T S L R +++ G++ C + Sbjct: 449 PHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHS--GEKPYVCIH 506 Query: 885 CDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGK 944 C F G+ LQRH+ H G KP +C +C A S+L AH+ +H+ EK ++C+ CGK Sbjct: 507 CQRQFADPGA-LQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGK 565 Query: 945 KFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCN 1004 +F L +H + H + + KC+VC L +H+ H KP+ C C N Sbjct: 566 RFVQSSQLANH-IRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFN 624 Query: 1005 ISGSLKRHYNRKHPNEEYANVGTGELAAEVLI 1036 +L+ H H + + E +EV + Sbjct: 625 RVDNLRSHVKTVHQGKAGIKILEPEEGSEVSV 656 Score = 108 bits (270), Expect = 3e-23 Identities = 70/223 (31%), Positives = 102/223 (45%), Gaps = 15/223 (6%) Query: 268 LKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-F 326 LK + CE C K ++ L H + H+ E Y+C C NL H H+GEK + Sbjct: 359 LKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPY 418 Query: 327 ACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVK 385 CDYC + H+E H K+H C C KK++ V NL H++ K + Sbjct: 419 QCDYCGRSFSDPTSKMRHLE-THDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCR 477 Query: 386 EALDELC--------LMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 E + L G++ Y C C+R+F + RH+ +H + P C +C Sbjct: 478 ECGKQFTTSGNLKRHLRIHSGEKP--YVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMC 535 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIK 478 G T+ +L HVR+H YVC C K+FV S +L HI+ Sbjct: 536 GKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIR 578 Score = 100 bits (248), Expect = 1e-20 Identities = 58/189 (30%), Positives = 89/189 (47%), Gaps = 11/189 (5%) Query: 273 CEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYC 331 C +C+K F +L+AHL+IH + P KC +C NL HLR H+GEK + C +C Sbjct: 448 CPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHC 507 Query: 332 SFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEAL-- 388 G L+ H+ R+H K C C K ++ +LI H+R H + V E Sbjct: 508 QRQFADPGALQRHV-RIHTGEKPCQCVMCGKAFTQASSLIAHVRQ-HTGEKPYVCERCGK 565 Query: 389 -----DELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 +L R + C +C + F N D +H+++H + P+ C+ CG G + Sbjct: 566 RFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNR 625 Query: 444 YQALELHVR 452 L HV+ Sbjct: 626 VDNLRSHVK 634 Score = 98.2 bits (243), Expect = 4e-20 Identities = 64/238 (26%), Positives = 96/238 (40%), Gaps = 43/238 (18%) Query: 830 YSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYF 889 + C C K F+ K HI+ + G++ C C F Sbjct: 306 HKCEDCGKEFTHTGNFKRHIRIH----------------------TGEKPFSCRECSKAF 343 Query: 890 MKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSK 949 + + + H H +KP+ C C + R S L H RHS E + C+ CGK F + Sbjct: 344 -SDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTS 402 Query: 950 GTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSL 1009 G LK H+L+H+ + K ++C C + + +RH+E H + K +C HC N G+L Sbjct: 403 GNLKRHQLVHSGE-KPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNL 461 Query: 1010 KRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 K H ++ I G LKC C + T RHL+ G K Sbjct: 462 KAHL-------------------KIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEK 500 Score = 90.1 bits (222), Expect = 1e-17 Identities = 62/224 (27%), Positives = 96/224 (42%), Gaps = 27/224 (12%) Query: 258 MKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVH 317 +K +L + K + C+YC + F S HL H +K +KCP C NL H Sbjct: 405 LKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAH 464 Query: 318 LRKHTGE-KFACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRD 375 L+ H + C C + G+LK H+ R+H K + C C+++++D L +H+R Sbjct: 465 LKIHIADGPLKCRECGKQFTTSGNLKRHL-RIHSGEKPYVCIHCQRQFADPGALQRHVR- 522 Query: 376 AHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 + T E Q C +C + F H+ H + P+ CE Sbjct: 523 -----------------IHTGEKPCQ----CVMCGKAFTQASSLIAHVRQHTGEKPYVCE 561 Query: 436 LCGHGATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTHI 477 CG + L H+R H + + C+VC K FV+ L HI Sbjct: 562 RCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHI 605 Score = 60.8 bits (146), Expect = 8e-09 Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 14/192 (7%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C K F L H+R H N +P+KC CS A +L+ H+ HTGEK + Sbjct: 556 KPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYL 615 Query: 328 CDYCSFTCLSKGHLKVHIERVHK-----KIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDK 382 CD C +L+ H++ VH+ KI + + V +++ +A Sbjct: 616 CDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGSEVSVVTVDDMVTLATEALAATAV 675 Query: 383 KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGAT 442 + +T + L + ++ + E D + H+L +AC+ CG Sbjct: 676 TQLTVVPVGAAVTADETEVLKAEISKAVKQVQEE-DPNTHIL-------YACDSCGDKFL 727 Query: 443 KYQALELHVRKH 454 +L HVR H Sbjct: 728 DANSLAQHVRIH 739 Score = 36.2 bits (82), Expect = 0.20 Identities = 43/184 (23%), Positives = 70/184 (38%), Gaps = 36/184 (19%) Query: 117 ECSKCCRKFSNTRQLRKHICIIVLNLGEEE------GEAGNESDLELEKKCKEDDREKAS 170 +CS C + F N L KHI +++ GE+ G N D L K + KA Sbjct: 587 KCSVCSKAFVNVGDLSKHI---IIHTGEKPYLCDKCGRGFNRVD-NLRSHVKTVHQGKAG 642 Query: 171 KRPRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATN 230 ++ + +E ++S + + T A T++ V G T A Sbjct: 643 ----------IKILEPEEGSEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVT-ADE 691 Query: 231 SETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHL 290 +E A++ A++Q E P ++ C+ C F +SL H+ Sbjct: 692 TEVLKAEI-------SKAVKQVQEEDPNTHI--------LYACDSCGDKFLDANSLAQHV 736 Query: 291 RIHT 294 RIHT Sbjct: 737 RIHT 740 >gi|38708324 zinc finger protein 93 [Homo sapiens] Length = 620 Score = 140 bits (353), Expect = 8e-33 Identities = 93/303 (30%), Positives = 131/303 (43%), Gaps = 40/303 (13%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 CE CGK F Y + H R HT E Y C +C + I + L +H I KC Sbjct: 203 CEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCEEC 262 Query: 804 GCDY---STPDKYK-----------------------LQAHLKVHTALDKRSYSCPVCEK 837 G + ST K+K L H K+HT ++ Y C C K Sbjct: 263 GKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTG--EKPYVCEECGK 320 Query: 838 SFSEDRLIKSHIKTNHPEVSMST--------ISEVLGRRVQLKGLIGKRAMKCPYCDFYF 889 +F R++ +H + + E S L R + +GK+ KC C F Sbjct: 321 AFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIH--MGKKHYKCEECGKAF 378 Query: 890 MKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSK 949 + + S L RH H G KP+KC C A + S L +H H+ EK + C+ CGK F + Sbjct: 379 IWS-SVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVAS 437 Query: 950 GTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSL 1009 TL H+++HT K +KC C Q L +H + H KP++C C + N S SL Sbjct: 438 STLSKHEIIHTGK-KPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSSL 496 Query: 1010 KRH 1012 +H Sbjct: 497 TKH 499 Score = 135 bits (339), Expect = 3e-31 Identities = 90/283 (31%), Positives = 123/283 (43%), Gaps = 28/283 (9%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 CE CGK F Y H R HT E Y C++C + I + L RH KC + Sbjct: 315 CEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKHYKC--E 372 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE-------- 855 C + L H +VHT ++ Y C C K+F + SH +++ E Sbjct: 373 ECGKAFIWSSVLTRHKRVHTG--EKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEEC 430 Query: 856 ----VSMSTIS--EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPF 909 V+ ST+S E++ GK+ KC C F ++ S L +H H G KP+ Sbjct: 431 GKAFVASSTLSKHEIIHT--------GKKPYKCEECGKAFNQSSS-LTKHKKIHTGEKPY 481 Query: 910 KCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCT 969 KC C A S+L H H+ EK + C+ CGK F TL HK +HT + K +KC Sbjct: 482 KCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIKHKKIHTRE-KPYKCE 540 Query: 970 VCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 C L H H KP+RC C + N S +L H Sbjct: 541 ECGKAFHLSTHLTTHKILHTGEKPYRCRECGKAFNHSATLSSH 583 Score = 119 bits (298), Expect = 2e-26 Identities = 81/274 (29%), Positives = 111/274 (40%), Gaps = 36/274 (13%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQC----HYSSITKNCLKRHVIQKHSNILL 798 +CE CGK F + H R HT E Y C +C YSS + + H +K Sbjct: 370 KCEECGKAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKP----Y 425 Query: 799 KCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSM 858 KC + C + L H +HT K+ Y C C K+F++ + H K + Sbjct: 426 KC--EECGKAFVASSTLSKHEIIHTG--KKPYKCEECGKAFNQSSSLTKHKKIH------ 475 Query: 859 STISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYAT 918 G++ KC C F S L +H H G KP+KC C A Sbjct: 476 ----------------TGEKPYKCEECGKAF-NQSSSLTKHKKIHTGEKPYKCEECGKAF 518 Query: 919 RSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQK 978 S L H H+ EK + C+ CGK F L +HK+LHT + K ++C C Sbjct: 519 NQSSTLIKHKKIHTREKPYKCEECGKAFHLSTHLTTHKILHTGE-KPYRCRECGKAFNHS 577 Query: 979 PQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L H + H KP+ C C + SL RH Sbjct: 578 ATLSSHKKIHSGEKPYECDKCGKAFISPSSLSRH 611 Score = 107 bits (268), Expect = 5e-23 Identities = 86/341 (25%), Positives = 129/341 (37%), Gaps = 23/341 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C+ GK+F + + H HT + + C +C + + L H C Sbjct: 146 QCDKYGKVFHKFSNSNRHNIRHTEKKPFKCIECGKAFNQFSTLITHKKIHTGEKPYIC-- 203 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 + C + L H ++HT ++ Y C C+K+F + H I T Sbjct: 204 EECGKAFKYSSALNTHKRIHTG--EKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCEE 261 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + + L K G++ KC C F S L +H H G KP+ C C Sbjct: 262 CGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAF-NQSSTLTKHKKIHTGEKPYVCEECGK 320 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A + L H H+ EK + C+ CGK F + TL H+ +H K +KC C Sbjct: 321 AFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGK-KHYKCEECGKAFI 379 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE--------YANVGTG 1028 L RH H KP++C C + S +L H R H E+ A V + Sbjct: 380 WSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSH-KRSHTGEKPYKCEECGKAFVASS 438 Query: 1029 ELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 L+ +I G KC C + +H K G K Sbjct: 439 TLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKKIHTGEK 479 Score = 107 bits (268), Expect = 5e-23 Identities = 67/228 (29%), Positives = 99/228 (43%), Gaps = 15/228 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +CE CGK F Y H R+HT E Y C +C + + + L +H I KC Sbjct: 398 KCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVASSTLSKHEIIHTGKKPYKC-- 455 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + C + L H K+HT ++ Y C C K+F++ + H K + E Sbjct: 456 EECGKAFNQSSSLTKHKKIHTG--EKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKC-- 511 Query: 863 EVLGRRVQLKGLIGK--------RAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLC 914 E G+ + K + KC C F + + L H H G KP++C C Sbjct: 512 EECGKAFNQSSTLIKHKKIHTREKPYKCEECGKAFHLS-THLTTHKILHTGEKPYRCREC 570 Query: 915 EYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTAD 962 A + L +H HS EK + CD CGK F S +L H+++HT + Sbjct: 571 GKAFNHSATLSSHKKIHSGEKPYECDKCGKAFISPSSLSRHEIIHTGE 618 Score = 104 bits (260), Expect = 5e-22 Identities = 102/381 (26%), Positives = 144/381 (37%), Gaps = 76/381 (19%) Query: 117 ECSKCCRKFSNTRQLRKHICIIVLNLG------EEEGEAGNESDLELEKKCKEDDREKAS 170 +C KC + F + L KH +++ G EE G+A N+S L K K EK Sbjct: 230 KCDKCDKAFIASSTLSKHE---IIHTGKKPYKCEECGKAFNQSST-LTKHKKIHTGEKPY 285 Query: 171 KRPRSQKTEKVQKISGKEARQLSGAKKPII---------SVVLTAHEAIPGATKIVPVEA 221 K K K + +G K + S +LT H+ I K P + Sbjct: 286 KCEECGKAFNQSSTLTKHKKIHTGEKPYVCEECGKAFKYSRILTTHKRIHTGEK--PYKC 343 Query: 222 GPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFK 281 S T S G + Y CE C K F Sbjct: 344 NKCGKAFIASSTLSRHEFIHMGKKHYK------------------------CEECGKAFI 379 Query: 282 FKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGH 340 + L H R+HT EKPYKC +C A + L+ H R HTGEK + C+ C ++ Sbjct: 380 WSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVASST 439 Query: 341 LKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGK 399 L H E +H K + C C K ++ +L KH KK+ G+ Sbjct: 440 LSKH-EIIHTGKKPYKCEECGKAFNQSSSLTKH---------KKI-----------HTGE 478 Query: 400 RQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG----HGATKYQALELHVRKHP 455 + Y C C + F +H +H + P+ CE CG +T + ++H R+ P Sbjct: 479 KP--YKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIKHKKIHTREKP 536 Query: 456 FVYVCAVCRKKFVSSIRLRTH 476 Y C C K F S L TH Sbjct: 537 --YKCEECGKAFHLSTHLTTH 555 Score = 102 bits (254), Expect = 2e-21 Identities = 104/383 (27%), Positives = 147/383 (38%), Gaps = 52/383 (13%) Query: 117 ECSKCCRKFSNTRQLRKHICIIVLNLG---EEEGEAGNESD-LELEKKCKEDDRE----- 167 +C +C + F+ + L KH I EE G+A N+S L KK ++ Sbjct: 258 KCEECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEE 317 Query: 168 --KASKRPRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKIVPVEAGPPE 225 KA K R T K K + K I S L+ HE I K E E Sbjct: 318 CGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKHYKCE----E 373 Query: 226 TGATN--SETTSADLVPRRGYQEYAIQQT----PYEQPMKSSRLGPTQLKIFTCEYCNKV 279 G S + G + Y ++ Y + S + T K + CE C K Sbjct: 374 CGKAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKA 433 Query: 280 FKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSK 338 F +L H IHT +KPYKC +C A ++L H + HTGEK + C+ C Sbjct: 434 FVASSTLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQS 493 Query: 339 GHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTRE 397 L H +++H K + C C K ++ LIKH KK+ Sbjct: 494 SSLTKH-KKIHTGEKPYKCEECGKAFNQSSTLIKH---------KKIH------------ 531 Query: 398 GKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG----HGATKYQALELHVRK 453 R+ Y C C + F H ++H + P+ C CG H AT ++H + Sbjct: 532 -TREKPYKCEECGKAFHLSTHLTTHKILHTGEKPYRCRECGKAFNHSATLSSHKKIHSGE 590 Query: 454 HPFVYVCAVCRKKFVSSIRLRTH 476 P Y C C K F+S L H Sbjct: 591 KP--YECDKCGKAFISPSSLSRH 611 Score = 100 bits (250), Expect = 7e-21 Identities = 73/229 (31%), Positives = 99/229 (43%), Gaps = 18/229 (7%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ K F C C K F +L H +IHT EKPY C +C A + LN H R HTGEK Sbjct: 168 TEKKPFKCIECGKAFNQFSTLITHKKIHTGEKPYICEECGKAFKYSSALNTHKRIHTGEK 227 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 + CD C ++ L H E +H K + C C K ++ L KH + + K Sbjct: 228 PYKCDKCDKAFIASSTLSKH-EIIHTGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYK 286 Query: 384 VKE---ALDELCLMTREGK---RQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 +E A ++ +T+ K + Y C C + FK H +H + P+ C C Sbjct: 287 CEECGKAFNQSSTLTKHKKIHTGEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKC 346 Query: 438 GHGATKYQALELHV-----RKHPFVYVCAVCRKKFVSSIRLRTHIKEVH 481 G L H +KH Y C C K F+ S L H K VH Sbjct: 347 GKAFIASSTLSRHEFIHMGKKH---YKCEECGKAFIWSSVLTRH-KRVH 391 Score = 97.4 bits (241), Expect = 7e-20 Identities = 68/219 (31%), Positives = 92/219 (42%), Gaps = 13/219 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C K FK+ +L H RIHT EKPYKC +C A + L+ H HTG+K + Sbjct: 199 KPYICEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYK 258 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C L H +++H K + C C K ++ L KH + H + V E Sbjct: 259 CEECGKAFNQSSTLTKH-KKIHTGEKPYKCEECGKAFNQSSTLTKH-KKIHTGEKPYVCE 316 Query: 387 ALDE-------LCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 + L R + Y C+ C + F RH +H K + CE CG Sbjct: 317 ECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKHYKCEECGK 376 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 L H R H Y C C K F S L +H Sbjct: 377 AFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSH 415 Score = 94.7 bits (234), Expect = 5e-19 Identities = 72/235 (30%), Positives = 99/235 (42%), Gaps = 15/235 (6%) Query: 254 YEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKAN 313 Y + + + T K + C+ C+K F +L H IHT +KPYKC +C A + Sbjct: 212 YSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCEECGKAFNQSST 271 Query: 314 LNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKK--KYSDVKNL 369 L H + HTGEK + C+ C L H +++H K + C C K KYS + Sbjct: 272 LTKHKKIHTGEKPYKCEECGKAFNQSSTLTKH-KKIHTGEKPYVCEECGKAFKYSRILTT 330 Query: 370 IKHIRDAHDP-QDKKVKEALDELCLMTRE-----GKRQLLYDCHICERKFKNELDRDRHM 423 K I P + K +A ++R GK+ Y C C + F RH Sbjct: 331 HKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKH--YKCEECGKAFIWSSVLTRHK 388 Query: 424 LVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 VH + P+ CE CG L H R H Y C C K FV+S L H Sbjct: 389 RVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVASSTLSKH 443 Score = 92.0 bits (227), Expect = 3e-18 Identities = 68/222 (30%), Positives = 102/222 (45%), Gaps = 13/222 (5%) Query: 266 TQLKIFTCEYCNKVF-KFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGE 324 TQ K+F C+ KVF KF +S + ++R HT +KP+KC +C A + L H + HTGE Sbjct: 140 TQSKVFQCDKYGKVFHKFSNSNRHNIR-HTEKKPFKCIECGKAFNQFSTLITHKKIHTGE 198 Query: 325 K-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP- 379 K + C+ C L H +R+H K + C C K + L KH I P Sbjct: 199 KPYICEECGKAFKYSSALNTH-KRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPY 257 Query: 380 QDKKVKEALDELCLMTREGK---RQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACEL 436 + ++ +A ++ +T+ K + Y C C + F +H +H + P+ CE Sbjct: 258 KCEECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEE 317 Query: 437 CGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 CG + L H R H Y C C K F++S L H Sbjct: 318 CGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRH 359 >gi|148727251 zinc finger protein 81 [Homo sapiens] Length = 661 Score = 140 bits (353), Expect = 8e-33 Identities = 90/286 (31%), Positives = 131/286 (45%), Gaps = 17/286 (5%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CGK F MH +THTRE Y C++C S + L RH L +C Sbjct: 332 CTKCGKAFIQNSELIMHEKTHTREKPYKCNECGKSFFQVSSLLRHQTTHTGEKLFECSEC 391 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 G +S L H K+HT +R + C C K+F++ ++ H + + E S I Sbjct: 392 GKGFSLNSA--LNIHQKIHTG--ERHHKCSECGKAFTQKSTLRMHQRIHTGE--RSYICT 445 Query: 864 VLGRR-VQLKGLI-------GKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCE 915 G+ +Q LI G++ +C C F S LQ H H G KP+ C+ C Sbjct: 446 QCGQAFIQKAHLIAHQRIHTGEKPYECSDCGKSFPSK-SQLQMHKRIHTGEKPYICTECG 504 Query: 916 YATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTA 975 A ++SNL H H+ EK+++C CGK F + H+ +HT + K + C C Sbjct: 505 KAFTNRSNLNTHQKSHTGEKSYICAECGKAFTDRSNFNKHQTIHTGE-KPYVCADCGRAF 563 Query: 976 AQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 QK +L+ H H + KP++C C S + LK H R H E+ Sbjct: 564 IQKSELITHQRIHTTEKPYKCPDCEKSFSKKPHLKVH-QRIHTGEK 608 Score = 123 bits (309), Expect = 1e-27 Identities = 79/272 (29%), Positives = 113/272 (41%), Gaps = 28/272 (10%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F + MH R HT E Y C+QC + I K L H +C Sbjct: 415 KCSECGKAFTQKSTLRMHQRIHTGERSYICTQCGQAFIQKAHLIAHQRIHTGEKPYEC-- 472 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 C S P K +LQ H ++HT ++ Y C C K+F+ + +H K++ Sbjct: 473 SDCGKSFPSKSQLQMHKRIHTG--EKPYICTECGKAFTNRSNLNTHQKSH---------- 520 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 G+++ C C F S+ +H H G KP+ C+ C A KS Sbjct: 521 ------------TGEKSYICAECGKAFTDR-SNFNKHQTIHTGEKPYVCADCGRAFIQKS 567 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 L H H+TEK + C C K F K LK H+ +HT + K + C C + Sbjct: 568 ELITHQRIHTTEKPYKCPDCEKSFSKKPHLKVHQRIHTGE-KPYICAECGKAFTDRSNFN 626 Query: 983 RHMEQHVSFKPFRCAHCHYSCNISGSLKRHYN 1014 +H H KP++C+ C L H N Sbjct: 627 KHQTIHTGDKPYKCSDCGKGFTQKSVLSMHRN 658 Score = 117 bits (293), Expect = 7e-26 Identities = 75/270 (27%), Positives = 116/270 (42%), Gaps = 28/270 (10%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F ++H + HT E + CS+C + K+ L+ H C Sbjct: 387 ECSECGKGFSLNSALNIHQKIHTGERHHKCSECGKAFTQKSTLRMHQRIHTGERSYICTQ 446 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 C + K L AH ++HT ++ Y C C KSF ++ H + + Sbjct: 447 --CGQAFIQKAHLIAHQRIHTG--EKPYECSDCGKSFPSKSQLQMHKRIH---------- 492 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 G++ C C F N S+L H +H G K + C+ C A +S Sbjct: 493 ------------TGEKPYICTECGKAF-TNRSNLNTHQKSHTGEKSYICAECGKAFTDRS 539 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 N H H+ EK ++C CG+ F K L +H+ +HT + K +KC C+ + ++KP L Sbjct: 540 NFNKHQTIHTGEKPYVCADCGRAFIQKSELITHQRIHTTE-KPYKCPDCEKSFSKKPHLK 598 Query: 983 RHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 H H KP+ CA C + + +H Sbjct: 599 VHQRIHTGEKPYICAECGKAFTDRSNFNKH 628 Score = 100 bits (250), Expect = 7e-21 Identities = 76/278 (27%), Positives = 114/278 (41%), Gaps = 29/278 (10%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C GK+F + HF + HT E + S+C K L ++ L C Sbjct: 276 CTEFGKIFTQRSHFFAPQKIHTVEKPHELSKCVNVFTQKPLLSIYLRVHRDEKLYICTK- 334 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C + +L H K HT ++ Y C C KSF + + H +T H Sbjct: 335 -CGKAFIQNSELIMHEKTHTR--EKPYKCNECGKSFFQVSSLLRH-QTTHT--------- 381 Query: 864 VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSN 923 G++ +C C F N S L H H G + KCS C A KS Sbjct: 382 ------------GEKLFECSECGKGFSLN-SALNIHQKIHTGERHHKCSECGKAFTQKST 428 Query: 924 LKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLR 983 L+ H H+ E++++C CG+ F K L +H+ +HT + K ++C+ C + K QL Sbjct: 429 LRMHQRIHTGERSYICTQCGQAFIQKAHLIAHQRIHTGE-KPYECSDCGKSFPSKSQLQM 487 Query: 984 HMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 H H KP+ C C + +L H + H E+ Sbjct: 488 HKRIHTGEKPYICTECGKAFTNRSNLNTH-QKSHTGEK 524 Score = 98.6 bits (244), Expect = 3e-20 Identities = 64/219 (29%), Positives = 94/219 (42%), Gaps = 13/219 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K+F C C K F +L H +IHT E+ +KC +C A K+ L +H R HTGE+ + Sbjct: 384 KLFECSECGKGFSLNSALNIHQKIHTGERHHKCSECGKAFTQKSTLRMHQRIHTGERSYI 443 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKV-- 384 C C + K HL H +R+H K + C C K + L H R H + + Sbjct: 444 CTQCGQAFIQKAHLIAH-QRIHTGEKPYECSDCGKSFPSKSQLQMHKR-IHTGEKPYICT 501 Query: 385 ---KEALDELCLMTREGKR--QLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 K + L T + + Y C C + F + + ++H +H + P+ C CG Sbjct: 502 ECGKAFTNRSNLNTHQKSHTGEKSYICAECGKAFTDRSNFNKHQTIHTGEKPYVCADCGR 561 Query: 440 GATKYQALELHVRKHPF--VYVCAVCRKKFVSSIRLRTH 476 + L H R H Y C C K F L+ H Sbjct: 562 AFIQKSELITHQRIHTTEKPYKCPDCEKSFSKKPHLKVH 600 Score = 95.5 bits (236), Expect = 3e-19 Identities = 59/194 (30%), Positives = 84/194 (43%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K LQ H RIHT EKPY C +C A ++NLN H + HTGEK + Sbjct: 468 KPYECSDCGKSFPSKSQLQMHKRIHTGEKPYICTECGKAFTNRSNLNTHQKSHTGEKSYI 527 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIR------DAHDPQ 380 C C + + H + +H K + C C + + LI H R P Sbjct: 528 CAECGKAFTDRSNFNKH-QTIHTGEKPYVCADCGRAFIQKSELITHQRIHTTEKPYKCPD 586 Query: 381 DKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 +K L + R + Y C C + F + + ++H +H P+ C CG G Sbjct: 587 CEKSFSKKPHLKVHQRIHTGEKPYICAECGKAFTDRSNFNKHQTIHTGDKPYKCSDCGKG 646 Query: 441 ATKYQALELHVRKH 454 T+ L +H H Sbjct: 647 FTQKSVLSMHRNIH 660 Score = 94.0 bits (232), Expect = 8e-19 Identities = 63/212 (29%), Positives = 87/212 (41%), Gaps = 31/212 (14%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 + C C + F K L AH RIHT EKPY+C C + K+ L +H R HTGEK + C Sbjct: 442 YICTQCGQAFIQKAHLIAHQRIHTGEKPYECSDCGKSFPSKSQLQMHKRIHTGEKPYICT 501 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQDKKVKE 386 C ++ +L H ++ H K + C C K ++D N KH I P Sbjct: 502 ECGKAFTNRSNLNTH-QKSHTGEKSYICAECGKAFTDRSNFNKHQTIHTGEKP------- 553 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 Y C C R F + + H +H + P+ C C +K Sbjct: 554 -----------------YVCADCGRAFIQKSELITHQRIHTTEKPYKCPDCEKSFSKKPH 596 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 L++H R H Y+CA C K F H Sbjct: 597 LKVHQRIHTGEKPYICAECGKAFTDRSNFNKH 628 Score = 92.4 bits (228), Expect = 2e-18 Identities = 61/228 (26%), Positives = 91/228 (39%), Gaps = 27/228 (11%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +RI EC CGK F + MH R HT E Y C++C + ++ L H Sbjct: 461 QRIHTGEKPYECSDCGKSFPSKSQLQMHKRIHTGEKPYICTECGKAFTNRSNLNTHQKSH 520 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 C C + D+ H +HT ++ Y C C ++F + + +H + + Sbjct: 521 TGEKSYICAE--CGKAFTDRSNFNKHQTIHTG--EKPYVCADCGRAFIQKSELITHQRIH 576 Query: 853 HPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCS 912 E + KCP C+ F K L+ H H G KP+ C+ Sbjct: 577 TTE----------------------KPYKCPDCEKSFSKK-PHLKVHQRIHTGEKPYICA 613 Query: 913 LCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHT 960 C A +SN H H+ +K + C CGK F K L H+ +HT Sbjct: 614 ECGKAFTDRSNFNKHQTIHTGDKPYKCSDCGKGFTQKSVLSMHRNIHT 661 Score = 89.0 bits (219), Expect = 3e-17 Identities = 60/219 (27%), Positives = 87/219 (39%), Gaps = 13/219 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K++ C C K F L H + HT EKPYKC +C + ++L H HTGEK F Sbjct: 328 KLYICTKCGKAFIQNSELIMHEKTHTREKPYKCNECGKSFFQVSSLLRHQTTHTGEKLFE 387 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C L +H +++H + H C C K ++ L H R H + + Sbjct: 388 CSECGKGFSLNSALNIH-QKIHTGERHHKCSECGKAFTQKSTLRMHQR-IHTGERSYICT 445 Query: 387 ALDE-------LCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 + L R + Y+C C + F ++ H +H + P+ C CG Sbjct: 446 QCGQAFIQKAHLIAHQRIHTGEKPYECSDCGKSFPSKSQLQMHKRIHTGEKPYICTECGK 505 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 T L H + H Y+CA C K F H Sbjct: 506 AFTNRSNLNTHQKSHTGEKSYICAECGKAFTDRSNFNKH 544 Score = 77.8 bits (190), Expect = 6e-14 Identities = 56/216 (25%), Positives = 88/216 (40%), Gaps = 27/216 (12%) Query: 265 PTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGE 324 P K TC K+F + A +IHT EKP++ +C K L+++LR H E Sbjct: 268 PIGEKANTCTEFGKIFTQRSHFFAPQKIHTVEKPHELSKCVNVFTQKPLLSIYLRVHRDE 327 Query: 325 K-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDK 382 K + C C + L +H E+ H + K + C C K + V +L++H Sbjct: 328 KLYICTKCGKAFIQNSELIMH-EKTHTREKPYKCNECGKSFFQVSSLLRH---------- 376 Query: 383 KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGAT 442 T G++ L++C C + F + H +H + C CG T Sbjct: 377 ----------QTTHTGEK--LFECSECGKGFSLNSALNIHQKIHTGERHHKCSECGKAFT 424 Query: 443 KYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + L +H R H Y+C C + F+ L H Sbjct: 425 QKSTLRMHQRIHTGERSYICTQCGQAFIQKAHLIAH 460 Score = 72.4 bits (176), Expect = 3e-12 Identities = 60/217 (27%), Positives = 85/217 (39%), Gaps = 11/217 (5%) Query: 276 CNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFT 334 C VF K L +LR+H +EK Y C +C A + L +H + HT EK + C+ C + Sbjct: 307 CVNVFTQKPLLSIYLRVHRDEKLYICTKCGKAFIQNSELIMHEKTHTREKPYKCNECGKS 366 Query: 335 CLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEA------ 387 L H + H K C C K +S L H + + K E Sbjct: 367 FFQVSSLLRH-QTTHTGEKLFECSECGKGFSLNSALNIHQKIHTGERHHKCSECGKAFTQ 425 Query: 388 LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQAL 447 L + R + Y C C + F + H +H + P+ C CG L Sbjct: 426 KSTLRMHQRIHTGERSYICTQCGQAFIQKAHLIAHQRIHTGEKPYECSDCGKSFPSKSQL 485 Query: 448 ELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVHG 482 ++H R H Y+C C K F + L TH K G Sbjct: 486 QMHKRIHTGEKPYICTECGKAFTNRSNLNTHQKSHTG 522 Score = 67.0 bits (162), Expect = 1e-10 Identities = 44/152 (28%), Positives = 64/152 (42%), Gaps = 11/152 (7%) Query: 875 IGKRAMKCPYCDFYFMKNGSDLQRHIWA----HEGVKPFKCSLCEYATRSKSNLKAHMNR 930 IG++A C F + H +A H KP + S C K L ++ Sbjct: 269 IGEKANTCTEFGKIFTQRS-----HFFAPQKIHTVEKPHELSKCVNVFTQKPLLSIYLRV 323 Query: 931 HSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVS 990 H EK ++C CGK F L H+ HT + K +KC C + Q LLRH H Sbjct: 324 HRDEKLYICTKCGKAFIQNSELIMHEKTHTRE-KPYKCNECGKSFFQVSSLLRHQTTHTG 382 Query: 991 FKPFRCAHCHYSCNISGSLKRHYNRKHPNEEY 1022 K F C+ C +++ +L H + H E + Sbjct: 383 EKLFECSECGKGFSLNSALNIH-QKIHTGERH 413 Score = 62.4 bits (150), Expect = 3e-09 Identities = 32/80 (40%), Positives = 40/80 (50%), Gaps = 1/80 (1%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K + C C K F K L+ H RIHT EKPY C +C A ++N N H HTG+K Sbjct: 577 TTEKPYKCPDCEKSFSKKPHLKVHQRIHTGEKPYICAECGKAFTDRSNFNKHQTIHTGDK 636 Query: 326 -FACDYCSFTCLSKGHLKVH 344 + C C K L +H Sbjct: 637 PYKCSDCGKGFTQKSVLSMH 656 Score = 60.1 bits (144), Expect = 1e-08 Identities = 46/182 (25%), Positives = 72/182 (39%), Gaps = 12/182 (6%) Query: 896 LQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSH 955 L ++ H K + C+ C A S L H H+ EK + C+ CGK F +L H Sbjct: 317 LSIYLRVHRDEKLYICTKCGKAFIQNSELIMHEKTHTREKPYKCNECGKSFFQVSSLLRH 376 Query: 956 KLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNR 1015 + HT + K F+C+ C + L H + H + +C+ C + +L+ H R Sbjct: 377 QTTHTGE-KLFECSECGKGFSLNSALNIHQKIHTGERHHKCSECGKAFTQKSTLRMH-QR 434 Query: 1016 KHPNEE--------YANVGTGELAAEVLIQQG--GLKCPVCSFVYGTKWEFNRHLKNKHG 1065 H E A + L A I G +C C + +K + H + G Sbjct: 435 IHTGERSYICTQCGQAFIQKAHLIAHQRIHTGEKPYECSDCGKSFPSKSQLQMHKRIHTG 494 Query: 1066 LK 1067 K Sbjct: 495 EK 496 Score = 52.4 bits (124), Expect = 3e-06 Identities = 53/213 (24%), Positives = 84/213 (39%), Gaps = 19/213 (8%) Query: 278 KVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEKF-ACDYCSFTCL 336 +VF S H HT K + QC ++K +L+ +++ GEK C Sbjct: 225 QVFTQNSSYSHHENTHTGVKFCERNQCGKVLSLKHSLSQNVKFPIGEKANTCTEFGKIFT 284 Query: 337 SKGHL----KVH-IERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQ---DKKVKEAL 388 + H K+H +E+ H+ K C ++ L ++R D + K +A Sbjct: 285 QRSHFFAPQKIHTVEKPHELSK-----CVNVFTQKPLLSIYLRVHRDEKLYICTKCGKAF 339 Query: 389 ---DELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQ 445 EL + + R+ Y C+ C + F RH H + F C CG G + Sbjct: 340 IQNSELIMHEKTHTREKPYKCNECGKSFFQVSSLLRHQTTHTGEKLFECSECGKGFSLNS 399 Query: 446 ALELHVRKHPFV--YVCAVCRKKFVSSIRLRTH 476 AL +H + H + C+ C K F LR H Sbjct: 400 ALNIHQKIHTGERHHKCSECGKAFTQKSTLRMH 432 Score = 47.0 bits (110), Expect = 1e-04 Identities = 20/54 (37%), Positives = 27/54 (50%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHT 322 K + C C K F + + H IHT +KPYKC C K+ L++H HT Sbjct: 608 KPYICAECGKAFTDRSNFNKHQTIHTGDKPYKCSDCGKGFTQKSVLSMHRNIHT 661 >gi|48717244 zinc finger protein 782 [Homo sapiens] Length = 699 Score = 140 bits (352), Expect = 1e-32 Identities = 99/342 (28%), Positives = 142/342 (41%), Gaps = 29/342 (8%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 E CGK H ++HT E Y C +C + K+ L++H KC Sbjct: 367 EYNECGKSCSMNSHLIWPQKSHTGEKPYECPECGKAFSEKSRLRKHQRTHTGEKPYKC-- 424 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSM---- 858 DGCD + K L+ H + HT ++ + C C KSF+ ++ H +T+ E Sbjct: 425 DGCDKAFSAKSGLRIHQRTHTG--EKPFECHECGKSFNYKSILIVHQRTHTGEKPFECNE 482 Query: 859 --STISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + S + G R + G+R KC C F K S L++H H G KP+KC+ C Sbjct: 483 CGKSFSHMSGLRNHRRTHTGERPYKCDECGKAF-KLKSGLRKHHRTHTGEKPYKCNQCGK 541 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A KS L+ H H+ EK + C+ CG+ F K L+ H HT + K ++C C T Sbjct: 542 AFGQKSQLRGHHRIHTGEKPYKCNHCGEAFSQKSNLRVHHRTHTGE-KPYQCEECGKTFR 600 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLI 1036 QK L H H KP+ C C + + L++H R H E+ N E Sbjct: 601 QKSNLRGHQRTHTGEKPYECNECGKAFSEKSVLRKH-QRTHTGEKPYNCNQ---CGEAFS 656 Query: 1037 QQGGL-------------KCPVCSFVYGTKWEFNRHLKNKHG 1065 Q+ L KC C + K H K G Sbjct: 657 QKSNLRVHQRTHTGEKPYKCDKCGRTFSQKSSLREHQKAHPG 698 Score = 115 bits (287), Expect = 3e-25 Identities = 68/226 (30%), Positives = 108/226 (47%), Gaps = 11/226 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + H RTHT E Y C +C + K+ L++H KC Sbjct: 479 ECNECGKSFSHMSGLRNHRRTHTGERPYKCDECGKAFKLKSGLRKHHRTHTGEKPYKC-- 536 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE--VSMST 860 + C + K +L+ H ++HT ++ Y C C ++FS+ ++ H +T+ E Sbjct: 537 NQCGKAFGQKSQLRGHHRIHTG--EKPYKCNHCGEAFSQKSNLRVHHRTHTGEKPYQCEE 594 Query: 861 ISEVLGRRVQLKGL----IGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + ++ L+G G++ +C C F + S L++H H G KP+ C+ C Sbjct: 595 CGKTFRQKSNLRGHQRTHTGEKPYECNECGKAFSEK-SVLRKHQRTHTGEKPYNCNQCGE 653 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTAD 962 A KSNL+ H H+ EK + CD CG+ F K +L+ H+ H D Sbjct: 654 AFSQKSNLRVHQRTHTGEKPYKCDKCGRTFSQKSSLREHQKAHPGD 699 Score = 110 bits (275), Expect = 8e-24 Identities = 71/225 (31%), Positives = 99/225 (44%), Gaps = 27/225 (12%) Query: 258 MKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVH 317 +++ R T + + C+ C K FK K L+ H R HT EKPYKC QC A K+ L H Sbjct: 493 LRNHRRTHTGERPYKCDECGKAFKLKSGLRKHHRTHTGEKPYKCNQCGKAFGQKSQLRGH 552 Query: 318 LRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRD 375 R HTGEK + C++C K +L+VH R H K + C C K + NL H R Sbjct: 553 HRIHTGEKPYKCNHCGEAFSQKSNLRVH-HRTHTGEKPYQCEECGKTFRQKSNLRGHQR- 610 Query: 376 AHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACE 435 T G++ Y+C+ C + F + +H H + P+ C Sbjct: 611 -------------------THTGEKP--YECNECGKAFSEKSVLRKHQRTHTGEKPYNCN 649 Query: 436 LCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIK 478 CG ++ L +H R H Y C C + F LR H K Sbjct: 650 QCGEAFSQKSNLRVHQRTHTGEKPYKCDKCGRTFSQKSSLREHQK 694 Score = 106 bits (265), Expect = 1e-22 Identities = 80/254 (31%), Positives = 105/254 (41%), Gaps = 22/254 (8%) Query: 244 YQEYAIQQTPYEQ-------PMKSSRLGP----TQLKIFTCEYCNKVFKFKHSLQAHLRI 292 +Q+ I+ PYE M S + P T K + C C K F K L+ H R Sbjct: 356 HQKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEKPYECPECGKAFSEKSRLRKHQRT 415 Query: 293 HTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKK 351 HT EKPYKC C A + K+ L +H R HTGEK F C C + K L VH +R H Sbjct: 416 HTGEKPYKCDGCDKAFSAKSGLRIHQRTHTGEKPFECHECGKSFNYKSILIVH-QRTHTG 474 Query: 352 IKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMT------REGKRQLLY 404 K C C K +S + L H R + K E L + R + Y Sbjct: 475 EKPFECNECGKSFSHMSGLRNHRRTHTGERPYKCDECGKAFKLKSGLRKHHRTHTGEKPY 534 Query: 405 DCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAV 462 C+ C + F + H +H + P+ C CG ++ L +H R H Y C Sbjct: 535 KCNQCGKAFGQKSQLRGHHRIHTGEKPYKCNHCGEAFSQKSNLRVHHRTHTGEKPYQCEE 594 Query: 463 CRKKFVSSIRLRTH 476 C K F LR H Sbjct: 595 CGKTFRQKSNLRGH 608 Score = 106 bits (265), Expect = 1e-22 Identities = 64/189 (33%), Positives = 89/189 (47%), Gaps = 25/189 (13%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F K L+ H RIHT EKPYKC C A + K+NL VH R HTGEK + Sbjct: 532 KPYKCNQCGKAFGQKSQLRGHHRIHTGEKPYKCNHCGEAFSQKSNLRVHHRTHTGEKPYQ 591 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C T K +L+ H +R H K + C C K +S+ L KH R Sbjct: 592 CEECGKTFRQKSNLRGH-QRTHTGEKPYECNECGKAFSEKSVLRKHQR------------ 638 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y+C+ C F + + H H + P+ C+ CG ++ + Sbjct: 639 --------THTGEKP--YNCNQCGEAFSQKSNLRVHQRTHTGEKPYKCDKCGRTFSQKSS 688 Query: 447 LELHVRKHP 455 L H + HP Sbjct: 689 LREHQKAHP 697 Score = 85.9 bits (211), Expect = 2e-16 Identities = 76/257 (29%), Positives = 105/257 (40%), Gaps = 35/257 (13%) Query: 776 HYS-SITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPV 834 HY + T NC R I K T G +S K ++ H +VH + Y Sbjct: 270 HYEFNDTGNCFCR--------ITHKTLTGGKSFS--QKSHIREHHRVHIGVKPFEYG--- 316 Query: 835 CEKSFSEDRLIKSHIKTN--------HPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCD 886 KSF+ + + H +T+ HP T S V K I + + C Sbjct: 317 --KSFNRNSTLPVHQRTHATDKYSDYHP--CTETFSYQSTFSVHQKVHIRAKPYEYNECG 372 Query: 887 FYFMKNGSDLQRHIW---AHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCG 943 K+ S IW +H G KP++C C A KS L+ H H+ EK + CD C Sbjct: 373 ----KSCSMNSHLIWPQKSHTGEKPYECPECGKAFSEKSRLRKHQRTHTGEKPYKCDGCD 428 Query: 944 KKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSC 1003 K F +K L+ H+ HT + K F+C C + K L+ H H KPF C C S Sbjct: 429 KAFSAKSGLRIHQRTHTGE-KPFECHECGKSFNYKSILIVHQRTHTGEKPFECNECGKSF 487 Query: 1004 NISGSLKRHYNRKHPNE 1020 + L+ H R H E Sbjct: 488 SHMSGLRNH-RRTHTGE 503 Score = 81.3 bits (199), Expect = 5e-15 Identities = 64/241 (26%), Positives = 91/241 (37%), Gaps = 43/241 (17%) Query: 276 CNKVFKFKHSLQAHLRIHT----------------------------NEKPYKCPQCSYA 307 C + F ++ + H ++H EKPY+CP+C A Sbjct: 343 CTETFSYQSTFSVHQKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEKPYECPECGKA 402 Query: 308 SAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSD 365 + K+ L H R HTGEK + CD C +K L++H +R H K C C K ++ Sbjct: 403 FSEKSRLRKHQRTHTGEKPYKCDGCDKAFSAKSGLRIH-QRTHTGEKPFECHECGKSFNY 461 Query: 366 VKNLIKHIRDAHDPQDKKVKEALDELCLM--------TREGKRQLLYDCHICERKFKNEL 417 LI H R + + E M T G+R Y C C + FK + Sbjct: 462 KSILIVHQRTHTGEKPFECNECGKSFSHMSGLRNHRRTHTGERP--YKCDECGKAFKLKS 519 Query: 418 DRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRT 475 +H H + P+ C CG + L H R H Y C C + F LR Sbjct: 520 GLRKHHRTHTGEKPYKCNQCGKAFGQKSQLRGHHRIHTGEKPYKCNHCGEAFSQKSNLRV 579 Query: 476 H 476 H Sbjct: 580 H 580 Score = 57.8 bits (138), Expect = 6e-08 Identities = 61/241 (25%), Positives = 87/241 (36%), Gaps = 50/241 (20%) Query: 278 KVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKAN--LNVHLRKHTGEKFACDY--CSF 333 K F K ++ H R+H KP++ Y + N L VH R H +K++ DY C+ Sbjct: 292 KSFSQKSHIREHHRVHIGVKPFE-----YGKSFNRNSTLPVHQRTHATDKYS-DYHPCTE 345 Query: 334 TCLSKGHLKVHIERVHKKIKQH-----------------------------CRFCKKKYS 364 T + VH ++VH + K + C C K +S Sbjct: 346 TFSYQSTFSVH-QKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEKPYECPECGKAFS 404 Query: 365 DVKNLIKHIRDAHDPQD-------KKVKEALDELCLMTREGKRQLLYDCHICERKFKNEL 417 + L KH R H + K A L + R + ++CH C + F + Sbjct: 405 EKSRLRKHQR-THTGEKPYKCDGCDKAFSAKSGLRIHQRTHTGEKPFECHECGKSFNYKS 463 Query: 418 DRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRT 475 H H + PF C CG + L H R H Y C C K F LR Sbjct: 464 ILIVHQRTHTGEKPFECNECGKSFSHMSGLRNHRRTHTGERPYKCDECGKAFKLKSGLRK 523 Query: 476 H 476 H Sbjct: 524 H 524 Score = 57.0 bits (136), Expect = 1e-07 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 11/94 (11%) Query: 242 RGYQEYAIQQTPYE-----------QPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHL 290 RG+Q + PYE ++ + T K + C C + F K +L+ H Sbjct: 606 RGHQRTHTGEKPYECNECGKAFSEKSVLRKHQRTHTGEKPYNCNQCGEAFSQKSNLRVHQ 665 Query: 291 RIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGE 324 R HT EKPYKC +C + K++L H + H G+ Sbjct: 666 RTHTGEKPYKCDKCGRTFSQKSSLREHQKAHPGD 699 Score = 42.7 bits (99), Expect = 0.002 Identities = 39/156 (25%), Positives = 57/156 (36%), Gaps = 23/156 (14%) Query: 921 KSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQ 980 KS+++ H H K GK F TL H+ H D K C T + + Sbjct: 297 KSHIREHHRVHIGVKPF---EYGKSFNRNSTLPVHQRTHATD-KYSDYHPCTETFSYQST 352 Query: 981 LLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQGG 1040 H + H+ KP+ C SC+++ L P + + TGE E Sbjct: 353 FSVHQKVHIRAKPYEYNECGKSCSMNSHLI------WPQKSH----TGEKPYE------- 395 Query: 1041 LKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDGDPK 1076 CP C + K +H + G K + DG K Sbjct: 396 --CPECGKAFSEKSRLRKHQRTHTGEKPYKCDGCDK 429 >gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens] Length = 620 Score = 139 bits (351), Expect = 1e-32 Identities = 92/287 (32%), Positives = 134/287 (46%), Gaps = 17/287 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + + +H +THT E Y C++C S I K L H HS K P Sbjct: 300 ECNECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIH----HSTHTGKKPH 355 Query: 803 D--GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE----- 855 + C + DK L H + HT ++ + C C KSF+E + H +T+ E Sbjct: 356 ECNECKKTFSDKSTLIIHQRTHTG--EKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYEC 413 Query: 856 -VSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLC 914 V T ++ V + G++ +C C+ F + S L H H G KP++C+ C Sbjct: 414 DVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQK-SYLMLHQRGHTGEKPYECNEC 472 Query: 915 EYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYT 974 E A KS L H H+ EK + C+ CGK F+ K L H+ +HT + K ++C VC Sbjct: 473 EKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGE-KPYECPVCWKA 531 Query: 975 AAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +QK QL+ H H KP+ C C + + H R H E+ Sbjct: 532 FSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVH-QRTHTGEK 577 Score = 134 bits (337), Expect = 5e-31 Identities = 98/359 (27%), Positives = 153/359 (42%), Gaps = 21/359 (5%) Query: 724 KKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKN 783 +++ SL +RI+ EC C K F + H +H RTHT E + C++C + K+ Sbjct: 197 RRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHTGEKPFGCTECGKAFSQKS 256 Query: 784 CLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDR 843 L H+ +CP C + +K + H + HT ++ Y C C K+F++ Sbjct: 257 QLIIHLRTHTGERPFECPE--CGKAFREKSTVIIHYRTHTG--EKPYECNECGKAFTQKS 312 Query: 844 LIKSHIKTNHPEVSM------STISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQ 897 + H KT+ E + + + L + GK+ +C C F + S L Sbjct: 313 NLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECNECKKTF-SDKSTLI 371 Query: 898 RHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKL 957 H H G KP KC+ C + KS L H H+ EK + CD+CGK F K L H+ Sbjct: 372 IHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVHQR 431 Query: 958 LHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKH 1017 H+ + K F+C C+ +QK L+ H H KP+ C C + + L H Sbjct: 432 THSGE-KPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSYLIIHQRTHT 490 Query: 1018 PNEEYANVGTGELAAE---VLIQQ------GGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 + Y G+ E ++I Q +CPVC + K + H + G K Sbjct: 491 EEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIHQRTHTGEK 549 Score = 113 bits (283), Expect = 1e-24 Identities = 78/260 (30%), Positives = 107/260 (41%), Gaps = 28/260 (10%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F + +H RTHT E Y C C + K+ L H +C Sbjct: 384 KCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVHQRTHSGEKPFEC-- 441 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + C+ + K L H + HT ++ Y C CEK+FS+ + H +T+ E Sbjct: 442 NECEKAFSQKSYLMLHQRGHTG--EKPYECNECEKAFSQKSYLIIHQRTHTEE------- 492 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 + KC C F + S L H H G KP++C +C A KS Sbjct: 493 ---------------KPYKCNECGKAFREK-SKLIIHQRIHTGEKPYECPVCWKAFSQKS 536 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 L H H+ EK + C CGK F+ K T H+ HT + K +KCT C QK L+ Sbjct: 537 QLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGE-KPYKCTECGKAFTQKSNLI 595 Query: 983 RHMEQHVSFKPFRCAHCHYS 1002 H H K H S Sbjct: 596 VHQRTHAGKKAHGRGHTRKS 615 Score = 105 bits (263), Expect = 2e-22 Identities = 72/228 (31%), Positives = 101/228 (44%), Gaps = 15/228 (6%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K C C K F K +L H R HT EKP+KC +C + K+ L VH R HTGEK Sbjct: 350 TGKKPHECNECKKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRTHTGEK 409 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIR--DAHDPQD 381 + CD C T K +L VH +R H K C C+K +S L+ H R P + Sbjct: 410 PYECDVCGKTFTQKSNLGVH-QRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYE 468 Query: 382 ----KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 +K L + R + Y C+ C + F+ + H +H + P+ C +C Sbjct: 469 CNECEKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPVC 528 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVC----RKKFVSSIRLRTHIKE 479 ++ L +H R H Y C C R+K ++ RTH E Sbjct: 529 WKAFSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGE 576 Score = 103 bits (258), Expect = 8e-22 Identities = 76/252 (30%), Positives = 102/252 (40%), Gaps = 41/252 (16%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F C C K F K L HLR HT E+P++CP+C A K+ + +H R HTGEK + Sbjct: 241 KPFGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHYRTHTGEKPYE 300 Query: 328 CDYCSFTCLSKGHLKVH-------------------IERV--------HKKIKQH-CRFC 359 C+ C K +L VH I+++ H K H C C Sbjct: 301 CNECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECNEC 360 Query: 360 KKKYSDVKNLIKHIRDAHDPQDKKVKEA------LDELCLMTREGKRQLLYDCHICERKF 413 KK +SD LI H R + K E L + R + Y+C +C + F Sbjct: 361 KKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTF 420 Query: 414 KNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSS- 470 + + H H + PF C C ++ L LH R H Y C C K F Sbjct: 421 TQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKS 480 Query: 471 ---IRLRTHIKE 479 I RTH +E Sbjct: 481 YLIIHQRTHTEE 492 Score = 100 bits (248), Expect = 1e-20 Identities = 70/221 (31%), Positives = 98/221 (44%), Gaps = 17/221 (7%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F C C K F K L H R HT EKP+ C +C A + K+ L +HLR HTGE+ F Sbjct: 213 KPFECTACRKTFSKKSHLIVHWRTHTGEKPFGCTECGKAFSQKSQLIIHLRTHTGERPFE 272 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQ-----D 381 C C K + +H R H K + C C K ++ NLI H + H + Sbjct: 273 CPECGKAFREKSTVIIHY-RTHTGEKPYECNECGKAFTQKSNLIVH-QKTHTGEKTYECT 330 Query: 382 KKVKEALDELCLM----TREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 K + + +L L+ T GK+ ++C+ C++ F ++ H H + P C C Sbjct: 331 KCGESFIQKLDLIIHHSTHTGKKP--HECNECKKTFSDKSTLIIHQRTHTGEKPHKCTEC 388 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 G + L +H R H Y C VC K F L H Sbjct: 389 GKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVH 429 Score = 94.7 bits (234), Expect = 5e-19 Identities = 59/194 (30%), Positives = 89/194 (45%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C K F K +L H R H+ EKP++C +C A + K+ L +H R HTGEK + Sbjct: 409 KPYECDVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYE 468 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQDK-- 382 C+ C K +L +H +R H + K + C C K + + LI H I P + Sbjct: 469 CNECEKAFSQKSYLIIH-QRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPV 527 Query: 383 --KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 K +L + R + Y C C + F+ + H H + P+ C CG Sbjct: 528 CWKAFSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGEKPYKCTECGKA 587 Query: 441 ATKYQALELHVRKH 454 T+ L +H R H Sbjct: 588 FTQKSNLIVHQRTH 601 Score = 90.5 bits (223), Expect = 9e-18 Identities = 60/217 (27%), Positives = 90/217 (41%), Gaps = 27/217 (12%) Query: 805 CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEV 864 C K L H ++ ++ + C C K+FS+ + H +T+ Sbjct: 192 CGKGLRRKKGLSLHQRIKNG--EKPFECTACRKTFSKKSHLIVHWRTH------------ 237 Query: 865 LGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNL 924 G++ C C F + S L H+ H G +PF+C C A R KS + Sbjct: 238 ----------TGEKPFGCTECGKAFSQK-SQLIIHLRTHTGERPFECPECGKAFREKSTV 286 Query: 925 KAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRH 984 H H+ EK + C+ CGK F K L H+ HT + K ++CT C + QK L+ H Sbjct: 287 IIHYRTHTGEKPYECNECGKAFTQKSNLIVHQKTHTGE-KTYECTKCGESFIQKLDLIIH 345 Query: 985 MEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 H KP C C + + +L H R H E+ Sbjct: 346 HSTHTGKKPHECNECKKTFSDKSTLIIH-QRTHTGEK 381 Score = 85.1 bits (209), Expect = 4e-16 Identities = 59/213 (27%), Positives = 89/213 (41%), Gaps = 27/213 (12%) Query: 725 KQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNC 784 ++ N + +R EC C K F + + +H R HT E Y C++C + K+ Sbjct: 422 QKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSY 481 Query: 785 LKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRL 844 L H KC + C + +K KL H ++HT ++ Y CPVC K+FS+ Sbjct: 482 LIIHQRTHTEEKPYKC--NECGKAFREKSKLIIHQRIHTG--EKPYECPVCWKAFSQKSQ 537 Query: 845 IKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHE 904 + H +T+ G++ C C F + S H H Sbjct: 538 LIIHQRTH----------------------TGEKPYACTECGKAFREK-STFTVHQRTHT 574 Query: 905 GVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTH 937 G KP+KC+ C A KSNL H H+ +K H Sbjct: 575 GEKPYKCTECGKAFTQKSNLIVHQRTHAGKKAH 607 Score = 84.0 bits (206), Expect = 8e-16 Identities = 47/111 (42%), Positives = 59/111 (53%), Gaps = 3/111 (2%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ K + C C K F+ K L H RIHT EKPY+CP C A + K+ L +H R HTGEK Sbjct: 490 TEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIHQRTHTGEK 549 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIR 374 +AC C K VH +R H K + C C K ++ NLI H R Sbjct: 550 PYACTECGKAFREKSTFTVH-QRTHTGEKPYKCTECGKAFTQKSNLIVHQR 599 Score = 82.8 bits (203), Expect = 2e-15 Identities = 59/218 (27%), Positives = 84/218 (38%), Gaps = 9/218 (4%) Query: 268 LKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-F 326 +K + + C K + K L H RI EKP++C C + K++L VH R HTGEK F Sbjct: 184 MKPYGYKECGKGLRRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHTGEKPF 243 Query: 327 ACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L +H+ + C C K + + +I H R + + E Sbjct: 244 GCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHYRTHTGEKPYECNE 303 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 L + + + Y+C C F +LD H H K P C C Sbjct: 304 CGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECNECKKT 363 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + L +H R H + C C K F L H Sbjct: 364 FSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVH 401 Score = 72.8 bits (177), Expect = 2e-12 Identities = 52/168 (30%), Positives = 67/168 (39%), Gaps = 25/168 (14%) Query: 264 GPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTG 323 G T K + C C K F K L H R HT EKPYKC +C A K+ L +H R HTG Sbjct: 460 GHTGEKPYECNECEKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTG 519 Query: 324 EK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQD 381 EK + C C K L +H +R H K + C C K + + H R Sbjct: 520 EKPYECPVCWKAFSQKSQLIIH-QRTHTGEKPYACTECGKAFREKSTFTVHQR------- 571 Query: 382 KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDK 429 T G++ Y C C + F + + H H K Sbjct: 572 -------------THTGEKP--YKCTECGKAFTQKSNLIVHQRTHAGK 604 Score = 68.6 bits (166), Expect = 4e-11 Identities = 39/117 (33%), Positives = 51/117 (43%), Gaps = 2/117 (1%) Query: 905 GVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGK 964 G+KP+ C R K L H + EK C C K F K L H HT + K Sbjct: 183 GMKPYGYKECGKGLRRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHTGE-K 241 Query: 965 QFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 F CT C +QK QL+ H+ H +PF C C + ++ HY R H E+ Sbjct: 242 PFGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHY-RTHTGEK 297 Score = 62.0 bits (149), Expect = 3e-09 Identities = 27/57 (47%), Positives = 33/57 (57%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K + C C K F+ K + H R HT EKPYKC +C A K+NL VH R H G+K Sbjct: 549 KPYACTECGKAFREKSTFTVHQRTHTGEKPYKCTECGKAFTQKSNLIVHQRTHAGKK 605 Score = 37.0 bits (84), Expect = 0.12 Identities = 39/156 (25%), Positives = 56/156 (35%), Gaps = 32/156 (20%) Query: 345 IERVHKKIKQHCRFCKKKYSDVKNLI-KHIRDAH-------------------DPQDKKV 384 IER H+ + C + +SD K +I K RD H D + Sbjct: 86 IERQHQDDQDKCLLMQVGFSDKKTIITKSARDCHEFGNILHLSTNLVASIQRPDKHESFG 145 Query: 385 KEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKY 444 +D L L +R YD + F E ++ + P+ + CG G + Sbjct: 146 NNMVDNLDLFSRSSAEN-KYDNGCAKLFFHTEYEK-----TNPGMKPYGYKECGKGLRRK 199 Query: 445 QALELHVR----KHPFVYVCAVCRKKFVSSIRLRTH 476 + L LH R + PF C CRK F L H Sbjct: 200 KGLSLHQRIKNGEKPF--ECTACRKTFSKKSHLIVH 233 >gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens] Length = 639 Score = 139 bits (351), Expect = 1e-32 Identities = 92/287 (32%), Positives = 134/287 (46%), Gaps = 17/287 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC CGK F + + +H +THT E Y C++C S I K L H HS K P Sbjct: 319 ECNECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIH----HSTHTGKKPH 374 Query: 803 D--GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPE----- 855 + C + DK L H + HT ++ + C C KSF+E + H +T+ E Sbjct: 375 ECNECKKTFSDKSTLIIHQRTHTG--EKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYEC 432 Query: 856 -VSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLC 914 V T ++ V + G++ +C C+ F + S L H H G KP++C+ C Sbjct: 433 DVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQK-SYLMLHQRGHTGEKPYECNEC 491 Query: 915 EYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYT 974 E A KS L H H+ EK + C+ CGK F+ K L H+ +HT + K ++C VC Sbjct: 492 EKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGE-KPYECPVCWKA 550 Query: 975 AAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +QK QL+ H H KP+ C C + + H R H E+ Sbjct: 551 FSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVH-QRTHTGEK 596 Score = 134 bits (337), Expect = 5e-31 Identities = 98/359 (27%), Positives = 153/359 (42%), Gaps = 21/359 (5%) Query: 724 KKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKN 783 +++ SL +RI+ EC C K F + H +H RTHT E + C++C + K+ Sbjct: 216 RRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHTGEKPFGCTECGKAFSQKS 275 Query: 784 CLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDR 843 L H+ +CP C + +K + H + HT ++ Y C C K+F++ Sbjct: 276 QLIIHLRTHTGERPFECPE--CGKAFREKSTVIIHYRTHTG--EKPYECNECGKAFTQKS 331 Query: 844 LIKSHIKTNHPEVSM------STISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQ 897 + H KT+ E + + + L + GK+ +C C F + S L Sbjct: 332 NLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECNECKKTF-SDKSTLI 390 Query: 898 RHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKL 957 H H G KP KC+ C + KS L H H+ EK + CD+CGK F K L H+ Sbjct: 391 IHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVHQR 450 Query: 958 LHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKH 1017 H+ + K F+C C+ +QK L+ H H KP+ C C + + L H Sbjct: 451 THSGE-KPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSYLIIHQRTHT 509 Query: 1018 PNEEYANVGTGELAAE---VLIQQ------GGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 + Y G+ E ++I Q +CPVC + K + H + G K Sbjct: 510 EEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIHQRTHTGEK 568 Score = 113 bits (283), Expect = 1e-24 Identities = 78/260 (30%), Positives = 107/260 (41%), Gaps = 28/260 (10%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F + +H RTHT E Y C C + K+ L H +C Sbjct: 403 KCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVHQRTHSGEKPFEC-- 460 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + C+ + K L H + HT ++ Y C CEK+FS+ + H +T+ E Sbjct: 461 NECEKAFSQKSYLMLHQRGHTG--EKPYECNECEKAFSQKSYLIIHQRTHTEE------- 511 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 + KC C F + S L H H G KP++C +C A KS Sbjct: 512 ---------------KPYKCNECGKAFREK-SKLIIHQRIHTGEKPYECPVCWKAFSQKS 555 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 L H H+ EK + C CGK F+ K T H+ HT + K +KCT C QK L+ Sbjct: 556 QLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGE-KPYKCTECGKAFTQKSNLI 614 Query: 983 RHMEQHVSFKPFRCAHCHYS 1002 H H K H S Sbjct: 615 VHQRTHAGKKAHGRGHTRKS 634 Score = 105 bits (263), Expect = 2e-22 Identities = 72/228 (31%), Positives = 101/228 (44%), Gaps = 15/228 (6%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K C C K F K +L H R HT EKP+KC +C + K+ L VH R HTGEK Sbjct: 369 TGKKPHECNECKKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRTHTGEK 428 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIR--DAHDPQD 381 + CD C T K +L VH +R H K C C+K +S L+ H R P + Sbjct: 429 PYECDVCGKTFTQKSNLGVH-QRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYE 487 Query: 382 ----KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 +K L + R + Y C+ C + F+ + H +H + P+ C +C Sbjct: 488 CNECEKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPVC 547 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVC----RKKFVSSIRLRTHIKE 479 ++ L +H R H Y C C R+K ++ RTH E Sbjct: 548 WKAFSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGE 595 Score = 103 bits (258), Expect = 8e-22 Identities = 76/252 (30%), Positives = 102/252 (40%), Gaps = 41/252 (16%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F C C K F K L HLR HT E+P++CP+C A K+ + +H R HTGEK + Sbjct: 260 KPFGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHYRTHTGEKPYE 319 Query: 328 CDYCSFTCLSKGHLKVH-------------------IERV--------HKKIKQH-CRFC 359 C+ C K +L VH I+++ H K H C C Sbjct: 320 CNECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECNEC 379 Query: 360 KKKYSDVKNLIKHIRDAHDPQDKKVKEA------LDELCLMTREGKRQLLYDCHICERKF 413 KK +SD LI H R + K E L + R + Y+C +C + F Sbjct: 380 KKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTF 439 Query: 414 KNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSS- 470 + + H H + PF C C ++ L LH R H Y C C K F Sbjct: 440 TQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKS 499 Query: 471 ---IRLRTHIKE 479 I RTH +E Sbjct: 500 YLIIHQRTHTEE 511 Score = 100 bits (248), Expect = 1e-20 Identities = 70/221 (31%), Positives = 98/221 (44%), Gaps = 17/221 (7%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F C C K F K L H R HT EKP+ C +C A + K+ L +HLR HTGE+ F Sbjct: 232 KPFECTACRKTFSKKSHLIVHWRTHTGEKPFGCTECGKAFSQKSQLIIHLRTHTGERPFE 291 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQ-----D 381 C C K + +H R H K + C C K ++ NLI H + H + Sbjct: 292 CPECGKAFREKSTVIIHY-RTHTGEKPYECNECGKAFTQKSNLIVH-QKTHTGEKTYECT 349 Query: 382 KKVKEALDELCLM----TREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELC 437 K + + +L L+ T GK+ ++C+ C++ F ++ H H + P C C Sbjct: 350 KCGESFIQKLDLIIHHSTHTGKKP--HECNECKKTFSDKSTLIIHQRTHTGEKPHKCTEC 407 Query: 438 GHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 G + L +H R H Y C VC K F L H Sbjct: 408 GKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVH 448 Score = 94.7 bits (234), Expect = 5e-19 Identities = 59/194 (30%), Positives = 89/194 (45%), Gaps = 9/194 (4%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C K F K +L H R H+ EKP++C +C A + K+ L +H R HTGEK + Sbjct: 428 KPYECDVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYE 487 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDPQDK-- 382 C+ C K +L +H +R H + K + C C K + + LI H I P + Sbjct: 488 CNECEKAFSQKSYLIIH-QRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPV 546 Query: 383 --KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 K +L + R + Y C C + F+ + H H + P+ C CG Sbjct: 547 CWKAFSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGEKPYKCTECGKA 606 Query: 441 ATKYQALELHVRKH 454 T+ L +H R H Sbjct: 607 FTQKSNLIVHQRTH 620 Score = 90.5 bits (223), Expect = 9e-18 Identities = 60/217 (27%), Positives = 90/217 (41%), Gaps = 27/217 (12%) Query: 805 CDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEV 864 C K L H ++ ++ + C C K+FS+ + H +T+ Sbjct: 211 CGKGLRRKKGLSLHQRIKNG--EKPFECTACRKTFSKKSHLIVHWRTH------------ 256 Query: 865 LGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNL 924 G++ C C F + S L H+ H G +PF+C C A R KS + Sbjct: 257 ----------TGEKPFGCTECGKAFSQK-SQLIIHLRTHTGERPFECPECGKAFREKSTV 305 Query: 925 KAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRH 984 H H+ EK + C+ CGK F K L H+ HT + K ++CT C + QK L+ H Sbjct: 306 IIHYRTHTGEKPYECNECGKAFTQKSNLIVHQKTHTGE-KTYECTKCGESFIQKLDLIIH 364 Query: 985 MEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 H KP C C + + +L H R H E+ Sbjct: 365 HSTHTGKKPHECNECKKTFSDKSTLIIH-QRTHTGEK 400 Score = 85.1 bits (209), Expect = 4e-16 Identities = 59/213 (27%), Positives = 89/213 (41%), Gaps = 27/213 (12%) Query: 725 KQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNC 784 ++ N + +R EC C K F + + +H R HT E Y C++C + K+ Sbjct: 441 QKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSY 500 Query: 785 LKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRL 844 L H KC + C + +K KL H ++HT ++ Y CPVC K+FS+ Sbjct: 501 LIIHQRTHTEEKPYKC--NECGKAFREKSKLIIHQRIHTG--EKPYECPVCWKAFSQKSQ 556 Query: 845 IKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHE 904 + H +T+ G++ C C F + S H H Sbjct: 557 LIIHQRTH----------------------TGEKPYACTECGKAFREK-STFTVHQRTHT 593 Query: 905 GVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTH 937 G KP+KC+ C A KSNL H H+ +K H Sbjct: 594 GEKPYKCTECGKAFTQKSNLIVHQRTHAGKKAH 626 Score = 84.0 bits (206), Expect = 8e-16 Identities = 47/111 (42%), Positives = 59/111 (53%), Gaps = 3/111 (2%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ K + C C K F+ K L H RIHT EKPY+CP C A + K+ L +H R HTGEK Sbjct: 509 TEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIHQRTHTGEK 568 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIR 374 +AC C K VH +R H K + C C K ++ NLI H R Sbjct: 569 PYACTECGKAFREKSTFTVH-QRTHTGEKPYKCTECGKAFTQKSNLIVHQR 618 Score = 82.8 bits (203), Expect = 2e-15 Identities = 59/218 (27%), Positives = 84/218 (38%), Gaps = 9/218 (4%) Query: 268 LKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-F 326 +K + + C K + K L H RI EKP++C C + K++L VH R HTGEK F Sbjct: 203 MKPYGYKECGKGLRRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHTGEKPF 262 Query: 327 ACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K L +H+ + C C K + + +I H R + + E Sbjct: 263 GCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHYRTHTGEKPYECNE 322 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 L + + + Y+C C F +LD H H K P C C Sbjct: 323 CGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECNECKKT 382 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + L +H R H + C C K F L H Sbjct: 383 FSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVH 420 Score = 72.8 bits (177), Expect = 2e-12 Identities = 52/168 (30%), Positives = 67/168 (39%), Gaps = 25/168 (14%) Query: 264 GPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTG 323 G T K + C C K F K L H R HT EKPYKC +C A K+ L +H R HTG Sbjct: 479 GHTGEKPYECNECEKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTG 538 Query: 324 EK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQD 381 EK + C C K L +H +R H K + C C K + + H R Sbjct: 539 EKPYECPVCWKAFSQKSQLIIH-QRTHTGEKPYACTECGKAFREKSTFTVHQR------- 590 Query: 382 KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDK 429 T G++ Y C C + F + + H H K Sbjct: 591 -------------THTGEKP--YKCTECGKAFTQKSNLIVHQRTHAGK 623 Score = 68.6 bits (166), Expect = 4e-11 Identities = 39/117 (33%), Positives = 51/117 (43%), Gaps = 2/117 (1%) Query: 905 GVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGK 964 G+KP+ C R K L H + EK C C K F K L H HT + K Sbjct: 202 GMKPYGYKECGKGLRRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHTGE-K 260 Query: 965 QFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 F CT C +QK QL+ H+ H +PF C C + ++ HY R H E+ Sbjct: 261 PFGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHY-RTHTGEK 316 Score = 62.0 bits (149), Expect = 3e-09 Identities = 27/57 (47%), Positives = 33/57 (57%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K + C C K F+ K + H R HT EKPYKC +C A K+NL VH R H G+K Sbjct: 568 KPYACTECGKAFREKSTFTVHQRTHTGEKPYKCTECGKAFTQKSNLIVHQRTHAGKK 624 Score = 37.0 bits (84), Expect = 0.12 Identities = 39/156 (25%), Positives = 56/156 (35%), Gaps = 32/156 (20%) Query: 345 IERVHKKIKQHCRFCKKKYSDVKNLI-KHIRDAH-------------------DPQDKKV 384 IER H+ + C + +SD K +I K RD H D + Sbjct: 105 IERQHQDDQDKCLLMQVGFSDKKTIITKSARDCHEFGNILHLSTNLVASIQRPDKHESFG 164 Query: 385 KEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKY 444 +D L L +R YD + F E ++ + P+ + CG G + Sbjct: 165 NNMVDNLDLFSRSSAEN-KYDNGCAKLFFHTEYEK-----TNPGMKPYGYKECGKGLRRK 218 Query: 445 QALELHVR----KHPFVYVCAVCRKKFVSSIRLRTH 476 + L LH R + PF C CRK F L H Sbjct: 219 KGLSLHQRIKNGEKPF--ECTACRKTFSKKSHLIVH 252 >gi|162417982 zinc finger protein 64 isoform d [Homo sapiens] Length = 645 Score = 139 bits (350), Expect = 2e-32 Identities = 91/328 (27%), Positives = 134/328 (40%), Gaps = 38/328 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +CE CGK F + H+R HT Y C C Y++ + L +H+ KC Sbjct: 176 KCEVCGKCFSRKDKLKTHMRCHTGVKPYKCKTCDYAAADSSSLNKHLRIHSDERPFKCQI 235 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH-IKTNHPEVSMSTI 861 C Y++ + +L HL+ HTA S +D + K++ + T + + + Sbjct: 236 --CPYASRNSSQLTVHLRSHTA-------------SELDDDVPKANCLSTESTDTPKAPV 280 Query: 862 SEVLGRRVQLKGLIGKRAMKC--PYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATR 919 + + +G+R C P C F + DL RH+ H G KP KC C+ Sbjct: 281 ITLPSEAREQMATLGERTFNCCYPGCHFKTVHGMKDLDRHLRIHTGDKPHKCEFCDKCFS 340 Query: 920 SKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKP 979 K NL HM H++ K H C +C +LK H +H +D + +KC +C Y + Sbjct: 341 RKDNLTMHMRCHTSVKPHKCHLCDYAAVDSSSLKKHLRIH-SDERPYKCQLCPYASRNSS 399 Query: 980 QLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQG 1039 QL H+ H PF+C C IS LKRH V +GE Sbjct: 400 QLTVHLRSHTGDTPFQCWLCSAKFKISSDLKRH----------MIVHSGEKP-------- 441 Query: 1040 GLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 KC C K H++ KH K Sbjct: 442 -FKCEFCDVRCTMKANLKSHIRIKHTFK 468 Score = 111 bits (277), Expect = 5e-24 Identities = 85/317 (26%), Positives = 125/317 (39%), Gaps = 81/317 (25%) Query: 798 LKCPTDGCDYSTPDKYK-LQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEV 856 L C GC + T K ++ HLK+HT + + C VC K FS +K+H++ + Sbjct: 144 LNCCYPGCQFKTAYGMKDMERHLKIHTG--DKPHKCEVCGKCFSRKDKLKTHMRCH---- 197 Query: 857 SMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 G + KC CD Y + S L +H+ H +PFKC +C Y Sbjct: 198 ------------------TGVKPYKCKTCD-YAAADSSSLNKHLRIHSDERPFKCQICPY 238 Query: 917 ATRSKSNLKAHMNRHST----------------------------------------EKT 936 A+R+ S L H+ H+ E+T Sbjct: 239 ASRNSSQLTVHLRSHTASELDDDVPKANCLSTESTDTPKAPVITLPSEAREQMATLGERT 298 Query: 937 HLCDMCGKKFKSKGTLKS---HKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKP 993 C G FK+ +K H +HT D K KC CD ++K L HM H S KP Sbjct: 299 FNCCYPGCHFKTVHGMKDLDRHLRIHTGD-KPHKCEFCDKCFSRKDNLTMHMRCHTSVKP 357 Query: 994 FRCAHCHYSCNISGSLKRHYNRKHPNEE--------YANVGTGELAAEVLIQQGG--LKC 1043 +C C Y+ S SLK+H R H +E YA+ + +L + G +C Sbjct: 358 HKCHLCDYAAVDSSSLKKHL-RIHSDERPYKCQLCPYASRNSSQLTVHLRSHTGDTPFQC 416 Query: 1044 PVCSFVYGTKWEFNRHL 1060 +CS + + RH+ Sbjct: 417 WLCSAKFKISSDLKRHM 433 Score = 97.1 bits (240), Expect = 1e-19 Identities = 72/288 (25%), Positives = 118/288 (40%), Gaps = 14/288 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +CE+C K F + + MH+R HT + C C Y+++ + LK+H+ KC Sbjct: 331 KCEFCDKCFSRKDNLTMHMRCHTSVKPHKCHLCDYAAVDSSSLKKHLRIHSDERPYKCQL 390 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 C Y++ + +L HL+ HT + C +C F +K H+ + E Sbjct: 391 --CPYASRNSSQLTVHLRSHTG--DTPFQCWLCSAKFKISSDLKRHMIVHSGEKPFK--C 444 Query: 863 EVLGRRVQLKGLIG-----KRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYA 917 E R +K + K KC +C F ++ +DL H H+ P KC C Y+ Sbjct: 445 EFCDVRCTMKANLKSHIRIKHTFKCLHCAFQ-GRDRADLLEHSRLHQADHPEKCPECSYS 503 Query: 918 TRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSH-KLLHTADGKQFKCTVCDYTAA 976 S + L+ H H ++ CD C K +L H +H + K Sbjct: 504 CSSAAALRVHSRVHCKDRPFKCDFCSFDTKRPSSLAKHVDKVHRDEAKTENRAPLGKEGL 563 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYAN 1024 ++ +H+ + V+ + FRC C S SL+ H + E N Sbjct: 564 REGS-SQHVAKIVTQRAFRCETCGASFVRDDSLRCHKKQHSDQSENKN 610 Score = 96.3 bits (238), Expect = 2e-19 Identities = 66/238 (27%), Positives = 101/238 (42%), Gaps = 28/238 (11%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T +K + C+ C+ SL HLRIH++E+P+KC C YAS + L VHLR HT + Sbjct: 198 TGVKPYKCKTCDYAAADSSSLNKHLRIHSDERPFKCQICPYASRNSSQLTVHLRSHTASE 257 Query: 326 FACDYCSFTCLS------------------KGHLKVHIERVHKKIKQHCRFCKKKYSDVK 367 D CLS + + ER C F K +K Sbjct: 258 LDDDVPKANCLSTESTDTPKAPVITLPSEAREQMATLGERTFNCCYPGCHF--KTVHGMK 315 Query: 368 NLIKHIR-DAHDPQDK-----KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDR 421 +L +H+R D K K D L + R + CH+C+ + + Sbjct: 316 DLDRHLRIHTGDKPHKCEFCDKCFSRKDNLTMHMRCHTSVKPHKCHLCDYAAVDSSSLKK 375 Query: 422 HMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHI 477 H+ +H D+ P+ C+LC + + L +H+R H + C +C KF S L+ H+ Sbjct: 376 HLRIHSDERPYKCQLCPYASRNSSQLTVHLRSHTGDTPFQCWLCSAKFKISSDLKRHM 433 Score = 85.9 bits (211), Expect = 2e-16 Identities = 80/292 (27%), Positives = 119/292 (40%), Gaps = 40/292 (13%) Query: 226 TGATNSETTSA-DLVPRRGYQEYAIQQTPYEQ-------PMKSSRLGPTQ---LKIFTCE 274 T T + T SA + V GYQ Y ++ Q P KS PT K C Sbjct: 88 TSETQTITVSAPEFVFEHGYQTYLPTESNENQTATVISLPAKSRTKKPTTPPAQKRLNCC 147 Query: 275 YCNKVFKFKHSL---QAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDY 330 Y FK + + + HL+IHT +KP+KC C + K L H+R HTG K + C Sbjct: 148 YPGCQFKTAYGMKDMERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHMRCHTGVKPYKCKT 207 Query: 331 CSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRD--AHDPQDKKVK-- 385 C + L H+ R+H + C+ C + L H+R A + D K Sbjct: 208 CDYAAADSSSLNKHL-RIHSDERPFKCQICPYASRNSSQLTVHLRSHTASELDDDVPKAN 266 Query: 386 ----EALD----ELCLMTREGKRQL------LYDCHICERKFK---NELDRDRHMLVHGD 428 E+ D + + E + Q+ ++C FK D DRH+ +H Sbjct: 267 CLSTESTDTPKAPVITLPSEAREQMATLGERTFNCCYPGCHFKTVHGMKDLDRHLRIHTG 326 Query: 429 KWPFACELCGHGATKYQALELHVRKHPFV--YVCAVCRKKFVSSIRLRTHIK 478 P CE C ++ L +H+R H V + C +C V S L+ H++ Sbjct: 327 DKPHKCEFCDKCFSRKDNLTMHMRCHTSVKPHKCHLCDYAAVDSSSLKKHLR 378 Score = 76.6 bits (187), Expect = 1e-13 Identities = 69/275 (25%), Positives = 102/275 (37%), Gaps = 59/275 (21%) Query: 214 TKIVPVEAGPPETGATNSETTSADLVPRRGYQEYAIQQTPYEQPMKS-------SRLGPT 266 T + P + + A +S + L + Y Q PY S S G T Sbjct: 353 TSVKPHKCHLCDYAAVDSSSLKKHLRIHSDERPYKCQLCPYASRNSSQLTVHLRSHTGDT 412 Query: 267 QLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLR-KHTGEK 325 F C C+ FK L+ H+ +H+ EKP+KC C +KANL H+R KHT + Sbjct: 413 P---FQCWLCSAKFKISSDLKRHMIVHSGEKPFKCEFCDVRCTMKANLKSHIRIKHTFKC 469 Query: 326 FACDY-------------------------CSFTCLSKGHLKVHIERVHKKIKQ-HCRFC 359 C + CS++C S L+VH RVH K + C FC Sbjct: 470 LHCAFQGRDRADLLEHSRLHQADHPEKCPECSYSCSSAAALRVH-SRVHCKDRPFKCDFC 528 Query: 360 KKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDR 419 +L KH+ H + K A + +EG R+ Sbjct: 529 SFDTKRPSSLAKHVDKVHRDEAKTENRA-----PLGKEGLRE----------------GS 567 Query: 420 DRHMLVHGDKWPFACELCGHGATKYQALELHVRKH 454 +H+ + F CE CG + +L H ++H Sbjct: 568 SQHVAKIVTQRAFRCETCGASFVRDDSLRCHKKQH 602 Score = 75.1 bits (183), Expect = 4e-13 Identities = 38/115 (33%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Query: 877 KRAMKC-PYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEK 935 KR C P C F D++RH+ H G KP KC +C K LK HM H+ K Sbjct: 142 KRLNCCYPGCQFKTAYGMKDMERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHMRCHTGVK 201 Query: 936 THLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVS 990 + C C +L H +H +D + FKC +C Y + QL H+ H + Sbjct: 202 PYKCKTCDYAAADSSSLNKHLRIH-SDERPFKCQICPYASRNSSQLTVHLRSHTA 255 Score = 69.3 bits (168), Expect = 2e-11 Identities = 57/246 (23%), Positives = 89/246 (36%), Gaps = 52/246 (21%) Query: 871 LKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNR 930 LK G + KC C F + L+ H+ H GVKP+KC C+YA S+L H+ Sbjct: 166 LKIHTGDKPHKCEVCGKCFSRKDK-LKTHMRCHTGVKPYKCKTCDYAAADSSSLNKHLRI 224 Query: 931 HSTEKTHLCDMCGKKFKSKGTLKSHKLLHTA-----DGKQFKCTVCDYTAAQKPQLL--- 982 HS E+ C +C ++ L H HTA D + C + T K ++ Sbjct: 225 HSDERPFKCQICPYASRNSSQLTVHLRSHTASELDDDVPKANCLSTESTDTPKAPVITLP 284 Query: 983 ----------------------------------RHMEQHVSFKPFRCAHCHYSCNISGS 1008 RH+ H KP +C C + + Sbjct: 285 SEAREQMATLGERTFNCCYPGCHFKTVHGMKDLDRHLRIHTGDKPHKCEFCDKCFSRKDN 344 Query: 1009 LKRH---YNRKHPNE----EYANVGTGELAAEVLI--QQGGLKCPVCSFVYGTKWEFNRH 1059 L H + P++ +YA V + L + I + KC +C + + H Sbjct: 345 LTMHMRCHTSVKPHKCHLCDYAAVDSSSLKKHLRIHSDERPYKCQLCPYASRNSSQLTVH 404 Query: 1060 LKNKHG 1065 L++ G Sbjct: 405 LRSHTG 410 Score = 32.3 bits (72), Expect = 2.9 Identities = 37/151 (24%), Positives = 59/151 (39%), Gaps = 21/151 (13%) Query: 963 GKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYN-------R 1015 G QFK TA + RH++ H KP +C C + LK H Sbjct: 150 GCQFK------TAYGMKDMERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHMRCHTGVKPY 203 Query: 1016 KHPNEEYANVGTGELAAEVLI--QQGGLKCPVCSFVYGTKWEFNRHLKNKHGLKVVEIDG 1073 K +YA + L + I + KC +C + + HL++ E+D Sbjct: 204 KCKTCDYAAADSSSLNKHLRIHSDERPFKCQICPYASRNSSQLTVHLRSH---TASELDD 260 Query: 1074 D-PKWE-TATEAPEEPSTQYLHI-TEAEEDV 1101 D PK +TE+ + P + + +EA E + Sbjct: 261 DVPKANCLSTESTDTPKAPVITLPSEAREQM 291 >gi|210031219 zinc finger protein 845 [Homo sapiens] Length = 970 Score = 139 bits (350), Expect = 2e-32 Identities = 92/316 (29%), Positives = 140/316 (44%), Gaps = 16/316 (5%) Query: 734 RIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKH 793 RI +C CGK F ++ + +H RTH+ E Y C +C + K+ L+RH Sbjct: 599 RIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHT 658 Query: 794 SNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKT 851 +C G +S K L H ++HT ++ Y C C K+F + + H I T Sbjct: 659 GEKPYRCNECGKTFSR--KSYLTCHRRLHTG--EKPYKCNECGKTFGRNSALIIHKAIHT 714 Query: 852 NHPEVSMSTISEVLGRRVQLKGLI----GKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVK 907 + + ++ L + G++ KC CD F + S L++H H G K Sbjct: 715 GEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSS-LEKHRRIHTGEK 773 Query: 908 PFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFK 967 P+KC +C+ A S+L H H+ EK + C+ CGK F+ L HK +H+ + K +K Sbjct: 774 PYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVIHKAIHSGE-KPYK 832 Query: 968 CTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGT 1027 C C T L H H KP++C+ C N +L RH+ R H E+ Sbjct: 833 CNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHH-RLHTGEKPYKCNK 891 Query: 1028 GELAAEVLIQQGGLKC 1043 +V QQ L C Sbjct: 892 ---CGKVFNQQAHLAC 904 Score = 136 bits (343), Expect = 1e-31 Identities = 105/366 (28%), Positives = 152/366 (41%), Gaps = 50/366 (13%) Query: 733 ERIRKVYGD---LECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHV 789 ER R+++ +C CGK F H R HT E Y C +C + K+ L+RH Sbjct: 455 ERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHR 514 Query: 790 IQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH- 848 I L KC G +S K L H ++HT ++ Y C C K+F + H Sbjct: 515 IIHTGEKLYKCNECGKTFSR--KSSLTRHCRLHTG--EKPYQCNECGKAFRGQSALIYHQ 570 Query: 849 --------IKTNHPEVSMSTISEVLGR-RVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRH 899 K N S + + R+ + +R+ KC C +F ++ S L H Sbjct: 571 AIHGIGKLYKCNDCHQVFSNATTIANHWRIHNE----ERSYKCNRCGKFF-RHRSYLAVH 625 Query: 900 IWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLH 959 H G KP+KC C+ A KSNL+ H H+ EK + C+ CGK F K L H+ LH Sbjct: 626 WRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLH 685 Query: 960 TADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH------- 1012 T + K +KC C T + L+ H H KP++C C + + SL H Sbjct: 686 TGE-KPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGE 744 Query: 1013 -----------YNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLK 1061 ++RK E++ + TGE KC VC +G +H + Sbjct: 745 KPYKCEECDKVFSRKSSLEKHRRIHTGEKP---------YKCKVCDKAFGRDSHLAQHTR 795 Query: 1062 NKHGLK 1067 G K Sbjct: 796 IHTGEK 801 Score = 132 bits (332), Expect = 2e-30 Identities = 102/339 (30%), Positives = 144/339 (42%), Gaps = 47/339 (13%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYS---SITKNCLKR-HVIQKHSNILL 798 +C+ CGK+F + + H R HT + Y C+ C + +T C R H +KH Sbjct: 244 KCDVCGKVFNQKRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKH----Y 299 Query: 799 KCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSM 858 KC G +S L H +HT ++SY C C K+FS+ + H Sbjct: 300 KCSECGKTFSRNSA--LVIHKAIHTG--EKSYKCNECGKTFSQTSYLVYH---------- 345 Query: 859 STISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYAT 918 RR+ G++ KC CD F S+L+RH H G KP+KC+ C Sbjct: 346 --------RRLHT----GEKPYKCEECDKAFSFK-SNLERHRKIHTGEKPYKCNECSRTF 392 Query: 919 RSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQK 978 KS+L H H+ EK + C+ CGK F +L H+ LHT + K +KC CD + K Sbjct: 393 SRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGE-KPYKCEECDEAFSFK 451 Query: 979 PQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE--------EYANVGTGEL 1030 L RH H KP++C C + + + SL H R H E + A L Sbjct: 452 SNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYH-RRLHTGEKPYKCEECDEAFSFKSNL 510 Query: 1031 AAEVLIQQGG--LKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 +I G KC C + K RH + G K Sbjct: 511 ERHRIIHTGEKLYKCNECGKTFSRKSSLTRHCRLHTGEK 549 Score = 132 bits (332), Expect = 2e-30 Identities = 85/288 (29%), Positives = 125/288 (43%), Gaps = 17/288 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F +H HT E Y C++C + K+ L H+ KC Sbjct: 692 KCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKC-- 749 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + CD K L+ H ++HT ++ Y C VC+K+F D + H + + E Sbjct: 750 EECDKVFSRKSSLEKHRRIHTG--EKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKC-- 805 Query: 863 EVLGRRVQLKGLI--------GKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLC 914 G+ + + G++ KC C F N S L+ H H G KP+KCS C Sbjct: 806 NECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHN-SALEIHKAIHTGEKPYKCSEC 864 Query: 915 EYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYT 974 K+NL H H+ EK + C+ CGK F + L H +HT + K +KC C T Sbjct: 865 GKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGE-KPYKCNECGKT 923 Query: 975 AAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEY 1022 L+ H H KP++C C N L RH+ R H +++ Sbjct: 924 FRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHH-RIHTGKKH 970 Score = 108 bits (270), Expect = 3e-23 Identities = 71/224 (31%), Positives = 103/224 (45%), Gaps = 12/224 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C+K F FK +L+ H +IHT EKPYKC +CS + K++L H R HTGEK + Sbjct: 353 KPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYK 412 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C T L H R+H K + C C + +S NL +H R + K + Sbjct: 413 CNDCGKTFSQMSSLVYH-RRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCND 471 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 L R + Y C C+ F + + +RH ++H + + C CG Sbjct: 472 CGKTFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKT 531 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVHG 482 ++ +L H R H Y C C K F L H + +HG Sbjct: 532 FSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYH-QAIHG 574 Score = 107 bits (268), Expect = 5e-23 Identities = 69/223 (30%), Positives = 102/223 (45%), Gaps = 12/223 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C++ F FK +LQ H RIHT EKPY+C +C + K+ L H R HTGEK + Sbjct: 633 KPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYK 692 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C T L +H + +H K + C C K +S +L H+R + K +E Sbjct: 693 CNECGKTFGRNSALIIH-KAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEE 751 Query: 387 ALDELCLMTREGKRQLL------YDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 + K + + Y C +C++ F + +H +H + P+ C CG Sbjct: 752 CDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKN 811 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 AL +H H Y C C K F + L H K +H Sbjct: 812 FRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIH-KAIH 853 Score = 102 bits (254), Expect = 2e-21 Identities = 68/212 (32%), Positives = 93/212 (43%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F L H R+HT EKPYKC +C A + K+NL H + HTGEK + Sbjct: 325 KSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYK 384 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ CS T K L H R+H K + C C K +S + +L+ H R Sbjct: 385 CNECSRTFSRKSSLTRH-RRLHTGEKPYKCNDCGKTFSQMSSLVYHRR------------ 431 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 L T E Y C C+ F + + +RH +H + P+ C CG ++ + Sbjct: 432 ------LHTGEKP----YKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSS 481 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 L H R H Y C C + F L H Sbjct: 482 LVYHRRLHTGEKPYKCEECDEAFSFKSNLERH 513 Score = 100 bits (250), Expect = 7e-21 Identities = 68/221 (30%), Positives = 96/221 (43%), Gaps = 12/221 (5%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 + C C K F+ + L H R H+ EKPYKC +C A + K+NL H R HTGEK + C+ Sbjct: 607 YKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCN 666 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----QDK 382 C T K +L H R+H K + C C K + LI H I P + Sbjct: 667 ECGKTFSRKSYLTCH-RRLHTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECG 725 Query: 383 KVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGAT 442 K L R + Y C C++ F + ++H +H + P+ C++C Sbjct: 726 KAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFG 785 Query: 443 KYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 + L H R H Y C C K F + L H K +H Sbjct: 786 RDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVIH-KAIH 825 Score = 99.8 bits (247), Expect = 1e-20 Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 12/238 (5%) Query: 254 YEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKAN 313 Y ++ ++ K + C+ C KVF K L H R HT +KPYKC C + + Sbjct: 226 YSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRRCHTGKKPYKCNDCGKTFSQELT 285 Query: 314 LNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIK 371 L H R HTGEK + C C T L +H + +H K + C C K +S L+ Sbjct: 286 LTCHHRLHTGEKHYKCSECGKTFSRNSALVIH-KAIHTGEKSYKCNECGKTFSQTSYLVY 344 Query: 372 HIRDAHDPQDKKVKEALDELCLMTREGKRQLL------YDCHICERKFKNELDRDRHMLV 425 H R + K +E + + + + Y C+ C R F + RH + Sbjct: 345 HRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNECSRTFSRKSSLTRHRRL 404 Query: 426 HGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 H + P+ C CG ++ +L H R H Y C C + F L H + +H Sbjct: 405 HTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERH-RRIH 461 Score = 83.6 bits (205), Expect = 1e-15 Identities = 76/272 (27%), Positives = 109/272 (40%), Gaps = 44/272 (16%) Query: 225 ETGATNSETTSADLVPRR----GYQEYAIQQTPYEQPMKSS----RLGPTQLKIFTCEYC 276 + G T S+T+S LV R G + Y ++ KS+ R+ T K++ C C Sbjct: 471 DCGKTFSQTSS--LVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNEC 528 Query: 277 NKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKH-TGEKFACDYC---- 331 K F K SL H R+HT EKPY+C +C A ++ L H H G+ + C+ C Sbjct: 529 GKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVF 588 Query: 332 SFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDEL 391 S H ++H E K C C K + L H R Sbjct: 589 SNATTIANHWRIHNEERSYK----CNRCGKFFRHRSYLAVHWR----------------- 627 Query: 392 CLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHV 451 T G++ Y C C+ F + + RH +H + P+ C CG ++ L H Sbjct: 628 ---THSGEKP--YKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHR 682 Query: 452 RKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 R H Y C C K F + L H K +H Sbjct: 683 RLHTGEKPYKCNECGKTFGRNSALIIH-KAIH 713 Score = 81.3 bits (199), Expect = 5e-15 Identities = 62/267 (23%), Positives = 110/267 (41%), Gaps = 15/267 (5%) Query: 810 PDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRV 869 P+ + Q K+ ++K S + S K+HI N+ +++ + V Sbjct: 149 PELHMFQTEGKIGNQVEKSINSASLVSTSQRISCRPKTHISKNYGNNFLNSSLLTQKQEV 208 Query: 870 QLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMN 929 ++ +++ +C F S L++H H G K +KC +C K L H Sbjct: 209 HMR----EKSFQCNESGKAF-NYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRR 263 Query: 930 RHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHV 989 H+ +K + C+ CGK F + TL H LHT + K +KC+ C T ++ L+ H H Sbjct: 264 CHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGE-KHYKCSECGKTFSRNSALVIHKAIHT 322 Query: 990 SFKPFRCAHCHYSCNISGSLKRH---------YNRKHPNEEYANVGTGELAAEVLIQQGG 1040 K ++C C + + + L H Y + ++ ++ E ++ + Sbjct: 323 GEKSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKP 382 Query: 1041 LKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 KC CS + K RH + G K Sbjct: 383 YKCNECSRTFSRKSSLTRHRRLHTGEK 409 Score = 77.8 bits (190), Expect = 6e-14 Identities = 50/163 (30%), Positives = 69/163 (42%), Gaps = 25/163 (15%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ +L+ H IHT EKPYKC +C KANL+ H R HTGEK + Sbjct: 829 KPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYK 888 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + HL H R+H K + C C K + L+ H + H + Sbjct: 889 CNKCGKVFNQQAHLACH-HRIHTGEKPYKCNECGKTFRHNSVLVIH-KTIHTGEKP---- 942 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDK 429 Y C+ C + F + RH +H K Sbjct: 943 -----------------YKCNECGKVFNRKAKLARHHRIHTGK 968 Score = 76.3 bits (186), Expect = 2e-13 Identities = 61/218 (27%), Positives = 84/218 (38%), Gaps = 11/218 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F C K F + L+ H IH K YKC C K L H R HTG+K + Sbjct: 213 KSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRRCHTGKKPYK 272 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C T + L H R+H K + C C K +S L+ H + K E Sbjct: 273 CNDCGKTFSQELTLTCH-HRLHTGEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYKCNE 331 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 L R + Y C C++ F + + +RH +H + P+ C C Sbjct: 332 CGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNECSRT 391 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 ++ +L H R H Y C C K F L H Sbjct: 392 FSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYH 429 Score = 75.1 bits (183), Expect = 4e-13 Identities = 52/188 (27%), Positives = 76/188 (40%), Gaps = 25/188 (13%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ +L H IH+ EKPYKC +C + L +H HTGEK + Sbjct: 801 KPYKCNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYK 860 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C C K +L H R+H K + C C K ++ +L H R Sbjct: 861 CSECGKVFNRKANLSRH-HRLHTGEKPYKCNKCGKVFNQQAHLACHHR------------ 907 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 G++ Y C+ C + F++ H +H + P+ C CG + Sbjct: 908 --------IHTGEKP--YKCNECGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAK 957 Query: 447 LELHVRKH 454 L H R H Sbjct: 958 LARHHRIH 965 Score = 54.7 bits (130), Expect = 5e-07 Identities = 26/57 (45%), Positives = 30/57 (52%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K + C C K F+ L H IHT EKPYKC +C KA L H R HTG+K Sbjct: 913 KPYKCNECGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGKK 969 Score = 51.2 bits (121), Expect = 6e-06 Identities = 49/195 (25%), Positives = 69/195 (35%), Gaps = 11/195 (5%) Query: 292 IHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHK 350 +H EK ++C + A + L H H G K + CD C K +L H R H Sbjct: 208 VHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACH-RRCHT 266 Query: 351 KIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEA------LDELCLMTREGKRQLL 403 K + C C K +S L H R + K E L + + Sbjct: 267 GKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHTGEKS 326 Query: 404 YDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCA 461 Y C+ C + F H +H + P+ CE C + LE H + H Y C Sbjct: 327 YKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCN 386 Query: 462 VCRKKFVSSIRLRTH 476 C + F L H Sbjct: 387 ECSRTFSRKSSLTRH 401 Score = 43.9 bits (102), Expect = 0.001 Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 2/99 (2%) Query: 725 KQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNC 784 ++ N S R+ +C CGK+F Q H H R HT E Y C++C + + Sbjct: 870 RKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKPYKCNECGKTFRHNSV 929 Query: 785 LKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHT 823 L H KC + C K KL H ++HT Sbjct: 930 LVIHKTIHTGEKPYKC--NECGKVFNRKAKLARHHRIHT 966 >gi|61676195 zinc finger protein 320 [Homo sapiens] Length = 509 Score = 137 bits (345), Expect = 6e-32 Identities = 85/276 (30%), Positives = 125/276 (45%), Gaps = 12/276 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C+ C K F + H H R H + Y C++C K L H KC Sbjct: 190 KCKVCDKAFKHDSHLAKHTRIHRGDKHYTCNECGKVFDQKATLACHHRSHTGEKPYKCNE 249 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 G +S L H ++HT ++ Y C C K+F+ + ++ H + T + Sbjct: 250 CGKTFSQTSH--LVYHHRLHTG--EKPYKCNECGKTFARNSVLVIHKAVHTAEKPYKCNE 305 Query: 861 ISEVLGRRVQLKGL----IGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V +R L G G++ +C CD F + S L+RH H G KP+KC +C+ Sbjct: 306 CGKVFKQRATLAGHRRVHTGEKPYRCEECDKVFSRK-SHLERHRRIHTGEKPYKCKVCDK 364 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A RS S L H H+ E+ + C+ CGK F +K L H+ LHT + K ++C CD Sbjct: 365 AFRSDSRLAEHQRVHTGERPYTCNECGKVFSTKAYLACHQKLHTGE-KLYECEECDKVYI 423 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 +K L RH H KP +C C + N L RH Sbjct: 424 RKSHLERHRRIHTGEKPHKCGDCGKAFNSPSHLIRH 459 Score = 119 bits (297), Expect = 2e-26 Identities = 100/373 (26%), Positives = 149/373 (39%), Gaps = 53/373 (14%) Query: 707 EHRSGITAFMKVLNSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTR 766 +H + +T K+ +S + + + I+ G LE + +H H R HT Sbjct: 108 DHEAPMTEIKKLTSSTDRYDQRHAGNKPIK---GQLESRF-------HLHLRRHRRIHTG 157 Query: 767 EHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALD 826 E Y C +C K+ L+ H I KC CD + +K +HL HT + Sbjct: 158 EKPYKCEECEKVFSCKSHLEIHRIIHTGEKPYKCKV--CDKA----FKHDSHLAKHTRIH 211 Query: 827 K--RSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPY 884 + + Y+C C K F + + H +++ G++ KC Sbjct: 212 RGDKHYTCNECGKVFDQKATLACHHRSH----------------------TGEKPYKCNE 249 Query: 885 CDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGK 944 C F + S L H H G KP+KC+ C S L H H+ EK + C+ CGK Sbjct: 250 CGKTFSQT-SHLVYHHRLHTGEKPYKCNECGKTFARNSVLVIHKAVHTAEKPYKCNECGK 308 Query: 945 KFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCN 1004 FK + TL H+ +HT + K ++C CD ++K L RH H KP++C C + Sbjct: 309 VFKQRATLAGHRRVHTGE-KPYRCEECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFR 367 Query: 1005 ISGSLKRHYNRKHPNEE-YANVGTGE-------LAAEVLIQQGG--LKCPVCSFVYGTKW 1054 L H R H E Y G+ LA + G +C C VY K Sbjct: 368 SDSRLAEH-QRVHTGERPYTCNECGKVFSTKAYLACHQKLHTGEKLYECEECDKVYIRKS 426 Query: 1055 EFNRHLKNKHGLK 1067 RH + G K Sbjct: 427 HLERHRRIHTGEK 439 Score = 101 bits (251), Expect = 5e-21 Identities = 67/232 (28%), Positives = 102/232 (43%), Gaps = 12/232 (5%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C CGK F +H HT E Y C++C + L H +C Sbjct: 274 KCNECGKTFARNSVLVIHKAVHTAEKPYKCNECGKVFKQRATLAGHRRVHTGEKPYRC-- 331 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 + CD K L+ H ++HT ++ Y C VC+K+F D + H + T + + Sbjct: 332 EECDKVFSRKSHLERHRRIHTG--EKPYKCKVCDKAFRSDSRLAEHQRVHTGERPYTCNE 389 Query: 861 ISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 +V + L K G++ +C CD +++ S L+RH H G KP KC C Sbjct: 390 CGKVFSTKAYLACHQKLHTGEKLYECEECDKVYIRK-SHLERHRRIHTGEKPHKCGDCGK 448 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKC 968 A S S+L H H+ +K++ C CGK F + L H+ + D FKC Sbjct: 449 AFNSPSHLIRHQRIHTGQKSYKCHQCGKVFSLRSLLAEHQKIPFGD-NCFKC 499 Score = 100 bits (250), Expect = 7e-21 Identities = 74/223 (33%), Positives = 95/223 (42%), Gaps = 12/223 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C KVF K L+ H IHT EKPYKC C A ++L H R H G+K + Sbjct: 159 KPYKCEECEKVFSCKSHLEIHRIIHTGEKPYKCKVCDKAFKHDSHLAKHTRIHRGDKHYT 218 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C K L H R H K + C C K +S +L+ H R + K E Sbjct: 219 CNECGKVFDQKATLACH-HRSHTGEKPYKCNECGKTFSQTSHLVYHHRLHTGEKPYKCNE 277 Query: 387 A------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 L + + Y C+ C + FK H VH + P+ CE C Sbjct: 278 CGKTFARNSVLVIHKAVHTAEKPYKCNECGKVFKQRATLAGHRRVHTGEKPYRCEECDKV 337 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 ++ LE H R H Y C VC K F S RL H + VH Sbjct: 338 FSRKSHLERHRRIHTGEKPYKCKVCDKAFRSDSRLAEH-QRVH 379 Score = 99.4 bits (246), Expect = 2e-20 Identities = 67/224 (29%), Positives = 99/224 (44%), Gaps = 14/224 (6%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K +TC C KVF K +L H R HT EKPYKC +C + ++L H R HTGEK + Sbjct: 215 KHYTCNECGKVFDQKATLACHHRSHTGEKPYKCNECGKTFSQTSHLVYHHRLHTGEKPYK 274 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C T L +H + VH K + C C K + L H R H + E Sbjct: 275 CNECGKTFARNSVLVIH-KAVHTAEKPYKCNECGKVFKQRATLAGH-RRVHTGEKPYRCE 332 Query: 387 ALDELCLMTREGKR-------QLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 D++ +R + Y C +C++ F+++ H VH + P+ C CG Sbjct: 333 ECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRSDSRLAEHQRVHTGERPYTCNECGK 392 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 + L H + H +Y C C K ++ L H + +H Sbjct: 393 VFSTKAYLACHQKLHTGEKLYECEECDKVYIRKSHLERH-RRIH 435 Score = 92.4 bits (228), Expect = 2e-18 Identities = 68/217 (31%), Positives = 91/217 (41%), Gaps = 27/217 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K + C C KVFK + +L H R+HT EKPY+C +C + K++L H R HTGEK Sbjct: 296 TAEKPYKCNECGKVFKQRATLAGHRRVHTGEKPYRCEECDKVFSRKSHLERHRRIHTGEK 355 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 + C C S L H +RVH + + C C K +S L H + Sbjct: 356 PYKCKVCDKAFRSDSRLAEH-QRVHTGERPYTCNECGKVFSTKAYLACHQK--------- 405 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 L T E LY+C C++ + + +RH +H + P C CG Sbjct: 406 ---------LHTGE----KLYECEECDKVYIRKSHLERHRRIHTGEKPHKCGDCGKAFNS 452 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIK 478 L H R H Y C C K F L H K Sbjct: 453 PSHLIRHQRIHTGQKSYKCHQCGKVFSLRSLLAEHQK 489 Score = 42.0 bits (97), Expect = 0.004 Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 273 CEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 C C K F L H RIHT +K YKC QC ++++ L H + G+ F C+ Sbjct: 443 CGDCGKAFNSPSHLIRHQRIHTGQKSYKCHQCGKVFSLRSLLAEHQKIPFGDNCFKCN 500 Score = 32.0 bits (71), Expect = 3.8 Identities = 15/45 (33%), Positives = 22/45 (48%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAI 310 T K + C C KVF + L H +I + +KC + S S+I Sbjct: 464 TGQKSYKCHQCGKVFSLRSLLAEHQKIPFGDNCFKCNEYSKPSSI 508 >gi|34303941 zinc finger protein 567 [Homo sapiens] Length = 616 Score = 137 bits (344), Expect = 8e-32 Identities = 87/284 (30%), Positives = 129/284 (45%), Gaps = 18/284 (6%) Query: 726 QMNTSLCERIRKVYGD--LECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKN 783 ++ T+L + R G+ EC C F + H H RTHT E Y C+ C S K Sbjct: 288 RLKTALTDHQRTHTGEKSYECLQCRNAFRLKSHLIRHQRTHTGEKPYECNDCGKSFRQKT 347 Query: 784 CLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDR 843 L H C C S K L H + HT ++ Y C C KSFS+ Sbjct: 348 TLSLHQRIHTGEKPYICKE--CGKSFHQKANLTVHQRTHTG--EKPYICNECGKSFSQKT 403 Query: 844 LIKSHIKTNHPEVSMSTISEVLGRRVQLKGLI--------GKRAMKCPYCDFYFMKNGSD 895 + H KT++ E I G+ + K + G+++ +CP+C F S Sbjct: 404 TLALHEKTHNEEKPY--ICSECGKSFRQKTTLVAHQRTHTGEKSYECPHCGKAFRMK-SY 460 Query: 896 LQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSH 955 L H H G KP++C+ C + K+NL H H+ EK ++C+ CGK F+ K TL H Sbjct: 461 LIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPYVCNECGKSFRQKATLTVH 520 Query: 956 KLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHC 999 + +HT K ++C C ++K L+ H H KP++C+ C Sbjct: 521 QKIHTGQ-KSYECPQCGKAFSRKSYLIHHQRTHTGEKPYKCSEC 563 Score = 130 bits (327), Expect = 8e-30 Identities = 88/297 (29%), Positives = 128/297 (43%), Gaps = 29/297 (9%) Query: 724 KKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKN 783 +++ SL +RI C+ CGK F + + +H RTHT E Y C++C S K Sbjct: 344 RQKTTLSLHQRIHTGEKPYICKECGKSFHQKANLTVHQRTHTGEKPYICNECGKSFSQKT 403 Query: 784 CLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDR 843 L H +K N C S K L AH + HT ++SY CP C K+F Sbjct: 404 TLALH--EKTHNEEKPYICSECGKSFRQKTTLVAHQRTHTG--EKSYECPHCGKAFRMKS 459 Query: 844 LIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAH 903 + H +T+ G++ +C C F + ++L H H Sbjct: 460 YLIDHHRTH----------------------TGEKPYECNECGKSFSQK-TNLNLHQRIH 496 Query: 904 EGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADG 963 G KP+ C+ C + R K+ L H H+ +K++ C CGK F K L H+ HT + Sbjct: 497 TGEKPYVCNECGKSFRQKATLTVHQKIHTGQKSYECPQCGKAFSRKSYLIHHQRTHTGE- 555 Query: 964 KQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNE 1020 K +KC+ C QK L+ H H KP+ C C S + +L H R H E Sbjct: 556 KPYKCSECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVH-QRTHKGE 611 Score = 104 bits (260), Expect = 5e-22 Identities = 70/214 (32%), Positives = 94/214 (43%), Gaps = 27/214 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F+ K +L H RIHT EKPY C +C + KANL VH R HTGEK + Sbjct: 332 KPYECNDCGKSFRQKTTLSLHQRIHTGEKPYICKECGKSFHQKANLTVHQRTHTGEKPYI 391 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + K L +H E+ H + K + C C K + L+ H R Sbjct: 392 CNECGKSFSQKTTLALH-EKTHNEEKPYICSECGKSFRQKTTLVAHQR------------ 438 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y+C C + F+ + H H + P+ C CG ++ Sbjct: 439 --------THTGEKS--YECPHCGKAFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTN 488 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIK 478 L LH R H YVC C K F L H K Sbjct: 489 LNLHQRIHTGEKPYVCNECGKSFRQKATLTVHQK 522 Score = 97.4 bits (241), Expect = 7e-20 Identities = 66/217 (30%), Positives = 96/217 (44%), Gaps = 31/217 (14%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F C C K F+ K +L H R HT EK Y+C QC A +K++L H R HTGEK + Sbjct: 276 KPFVCNECGKSFRLKTALTDHQRTHTGEKSYECLQCRNAFRLKSHLIRHQRTHTGEKPYE 335 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + K L +H +R+H K + C+ C K + NL H R Sbjct: 336 CNDCGKSFRQKTTLSLH-QRIHTGEKPYICKECGKSFHQKANLTVHQR------------ 382 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y C+ C + F + H H ++ P+ C CG + Sbjct: 383 --------THTGEKP--YICNECGKSFSQKTTLALHEKTHNEEKPYICSECGKSFRQKTT 432 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 L H R H Y C C K F R+++++ + H Sbjct: 433 LVAHQRTHTGEKSYECPHCGKAF----RMKSYLIDHH 465 Score = 97.4 bits (241), Expect = 7e-20 Identities = 60/188 (31%), Positives = 87/188 (46%), Gaps = 25/188 (13%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C +C K F+ K L H R HT EKPY+C +C + + K NLN+H R HTGEK + Sbjct: 444 KSYECPHCGKAFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPYV 503 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + K L VH +++H K + C C K +S LI H R Sbjct: 504 CNECGKSFRQKATLTVH-QKIHTGQKSYECPQCGKAFSRKSYLIHHQR------------ 550 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y C C + F+ + + H H + P+ C CG + + Sbjct: 551 --------THTGEKP--YKCSECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRN 600 Query: 447 LELHVRKH 454 L +H R H Sbjct: 601 LIVHQRTH 608 Score = 95.5 bits (236), Expect = 3e-19 Identities = 67/214 (31%), Positives = 92/214 (42%), Gaps = 27/214 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K TC C K F K L H IH+ EKPY+C QC A K+ L H R HTGEK F Sbjct: 220 KKHTCNECGKSFCRKSVLILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQRTHTGEKPFV 279 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + K L H +R H K + C C+ + +LI+H R Sbjct: 280 CNECGKSFRLKTALTDH-QRTHTGEKSYECLQCRNAFRLKSHLIRHQR------------ 326 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 T G++ Y+C+ C + F+ + H +H + P+ C+ CG + Sbjct: 327 --------THTGEKP--YECNDCGKSFRQKTTLSLHQRIHTGEKPYICKECGKSFHQKAN 376 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIK 478 L +H R H Y+C C K F L H K Sbjct: 377 LTVHQRTHTGEKPYICNECGKSFSQKTTLALHEK 410 Score = 82.0 bits (201), Expect = 3e-15 Identities = 59/199 (29%), Positives = 84/199 (42%), Gaps = 10/199 (5%) Query: 823 TALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKC 882 T +S+ CEKSF + + +H + E V ++ + + K C Sbjct: 172 TETPAQSFGYNDCEKSFLQRGGLITHSRPYKGENP-----SVYNKKRRATNIEKKHT--C 224 Query: 883 PYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMC 942 C F + S L H H KP++C C A R KS L H H+ EK +C+ C Sbjct: 225 NECGKSFCRK-SVLILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQRTHTGEKPFVCNEC 283 Query: 943 GKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYS 1002 GK F+ K L H+ HT + K ++C C K L+RH H KP+ C C S Sbjct: 284 GKSFRLKTALTDHQRTHTGE-KSYECLQCRNAFRLKSHLIRHQRTHTGEKPYECNDCGKS 342 Query: 1003 CNISGSLKRHYNRKHPNEE 1021 +L H R H E+ Sbjct: 343 FRQKTTLSLH-QRIHTGEK 360 Score = 79.7 bits (195), Expect = 2e-14 Identities = 57/196 (29%), Positives = 79/196 (40%), Gaps = 27/196 (13%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 EC +CGK F + + H RTHT E Y C++C S K L H C Sbjct: 447 ECPHCGKAFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPYVC-- 504 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 + C S K L H K+HT ++SY CP C K+FS + H +T+ Sbjct: 505 NECGKSFRQKATLTVHQKIHTG--QKSYECPQCGKAFSRKSYLIHHQRTH---------- 552 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 G++ KC C F + ++L H H G KP+ C+ C + K Sbjct: 553 ------------TGEKPYKCSECGKCFRQK-TNLIVHQRTHTGEKPYVCNECGKSFSYKR 599 Query: 923 NLKAHMNRHSTEKTHL 938 NL H H E + Sbjct: 600 NLIVHQRTHKGENIEM 615 Score = 71.6 bits (174), Expect = 4e-12 Identities = 39/86 (45%), Positives = 46/86 (53%), Gaps = 2/86 (2%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K + C C K F K L H R HT EKPYKC +C K NL VH R HTGEK Sbjct: 525 TGQKSYECPQCGKAFSRKSYLIHHQRTHTGEKPYKCSECGKCFRQKTNLIVHQRTHTGEK 584 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHK 350 + C+ C + K +L VH +R HK Sbjct: 585 PYVCNECGKSFSYKRNLIVH-QRTHK 609 Score = 57.4 bits (137), Expect = 8e-08 Identities = 26/56 (46%), Positives = 32/56 (57%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGE 324 K + C C K F+ K +L H R HT EKPY C +C + + K NL VH R H GE Sbjct: 556 KPYKCSECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVHQRTHKGE 611 Score = 57.0 bits (136), Expect = 1e-07 Identities = 41/137 (29%), Positives = 55/137 (40%), Gaps = 20/137 (14%) Query: 934 EKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKP 993 EK H C+ CGK F K L H+ +H+ + K ++C C +K L+ H H KP Sbjct: 219 EKKHTCNECGKSFCRKSVLILHQGIHSEE-KPYQCHQCGNAFRRKSYLIDHQRTHTGEKP 277 Query: 994 FRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTK 1053 F C C S + +L H R H TGE + E C C + K Sbjct: 278 FVCNECGKSFRLKTALTDH-QRTH---------TGEKSYE---------CLQCRNAFRLK 318 Query: 1054 WEFNRHLKNKHGLKVVE 1070 RH + G K E Sbjct: 319 SHLIRHQRTHTGEKPYE 335 >gi|57165430 zinc finger protein ZNF468 isoform 1 [Homo sapiens] Length = 469 Score = 136 bits (343), Expect = 1e-31 Identities = 91/308 (29%), Positives = 141/308 (45%), Gaps = 19/308 (6%) Query: 720 NSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSS 779 +SL KK L E+ +C+ CGK+F + + H R HT E Y C++C + Sbjct: 174 SSLLKKHQIIHLEEK------QCKCDVCGKVFNQKRYLACHRRCHTGEKPYKCNECGKTF 227 Query: 780 ITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSF 839 + L H +C + CD K L+ H ++HT ++ Y C VC+++F Sbjct: 228 GHNSSLFIHKALHTGEKPYEC--EECDKVFSRKSHLERHKRIHTG--EKPYKCKVCDEAF 283 Query: 840 SEDRLIKSH--IKTNHPEVSMSTISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNG 893 + + + H + T + + +V R L + G++ KC CD F + Sbjct: 284 AYNSYLAKHTILHTGEKPYTCNECGKVFNRLSTLARHHRLHTGEKPYKCEECDKVFSRK- 342 Query: 894 SDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLK 953 S L+RH H G KP+KC C KSNL+ H H+ EK + C +C K F+ L Sbjct: 343 SHLERHRRIHSGEKPYKCEECCKVFSRKSNLERHRRIHTGEKPYKCKVCDKAFQRDSHLA 402 Query: 954 SHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHY 1013 H+ +HT + K +KC C T Q L+ H H KP++C C + + SL H+ Sbjct: 403 QHQRVHTGE-KPYKCNECGKTFGQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYHH 461 Query: 1014 NRKHPNEE 1021 R H E+ Sbjct: 462 -RLHSGEK 468 Score = 121 bits (303), Expect = 5e-27 Identities = 79/251 (31%), Positives = 115/251 (45%), Gaps = 28/251 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 ECE C K+F + H + H R HT E Y C C + + L +H I C Sbjct: 247 ECEECDKVFSRKSHLERHKRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYTCNE 306 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 G ++ L H ++HT ++ Y C C+K FS KSH++ + Sbjct: 307 CGKVFNRLST--LARHHRLHTG--EKPYKCEECDKVFSR----KSHLERH---------- 348 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 RR+ G++ KC C F + S+L+RH H G KP+KC +C+ A + S Sbjct: 349 ----RRIHS----GEKPYKCEECCKVFSRK-SNLERHRRIHTGEKPYKCKVCDKAFQRDS 399 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 +L H H+ EK + C+ CGK F +L H+ LHT + K +KC C T +Q L+ Sbjct: 400 HLAQHQRVHTGEKPYKCNECGKTFGQTSSLIIHRRLHTGE-KPYKCNECGKTFSQMSSLV 458 Query: 983 RHMEQHVSFKP 993 H H KP Sbjct: 459 YHHRLHSGEKP 469 Score = 119 bits (297), Expect = 2e-26 Identities = 89/304 (29%), Positives = 123/304 (40%), Gaps = 47/304 (15%) Query: 764 HTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHT 823 H RE + C Q S + LK+H I KC D C K L H + HT Sbjct: 156 HMREKSFECIQSFKSFNCSSLLKKHQIIHLEEKQCKC--DVCGKVFNQKRYLACHRRCHT 213 Query: 824 ALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCP 883 ++ Y C C K+F + + H K H G++ +C Sbjct: 214 G--EKPYKCNECGKTFGHNSSLFIH-KALH---------------------TGEKPYECE 249 Query: 884 YCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCG 943 CD F + S L+RH H G KP+KC +C+ A S L H H+ EK + C+ CG Sbjct: 250 ECDKVFSRK-SHLERHKRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYTCNECG 308 Query: 944 KKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSC 1003 K F TL H LHT + K +KC CD ++K L RH H KP++C C C Sbjct: 309 KVFNRLSTLARHHRLHTGE-KPYKCEECDKVFSRKSHLERHRRIHSGEKPYKCEEC---C 364 Query: 1004 NISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNK 1063 + ++RK E + + TGE KC VC + +H + Sbjct: 365 KV-------FSRKSNLERHRRIHTGEKP---------YKCKVCDKAFQRDSHLAQHQRVH 408 Query: 1064 HGLK 1067 G K Sbjct: 409 TGEK 412 Score = 107 bits (267), Expect = 7e-23 Identities = 71/219 (32%), Positives = 99/219 (45%), Gaps = 12/219 (5%) Query: 273 CEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYC 331 C+ C KVF K L H R HT EKPYKC +C ++L +H HTGEK + C+ C Sbjct: 192 CDVCGKVFNQKRYLACHRRCHTGEKPYKCNECGKTFGHNSSLFIHKALHTGEKPYECEEC 251 Query: 332 SFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----QDKKV 384 K HL+ H +R+H K + C+ C + ++ L KH + P + KV Sbjct: 252 DKVFSRKSHLERH-KRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYTCNECGKV 310 Query: 385 KEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKY 444 L L R + Y C C++ F + +RH +H + P+ CE C ++ Sbjct: 311 FNRLSTLARHHRLHTGEKPYKCEECDKVFSRKSHLERHRRIHSGEKPYKCEECCKVFSRK 370 Query: 445 QALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 LE H R H Y C VC K F L H + VH Sbjct: 371 SNLERHRRIHTGEKPYKCKVCDKAFQRDSHLAQH-QRVH 408 Score = 100 bits (248), Expect = 1e-20 Identities = 68/218 (31%), Positives = 96/218 (44%), Gaps = 11/218 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C+KVF K L+ H RIHT EKPYKC C A A + L H HTGEK + Sbjct: 244 KPYECEECDKVFSRKSHLERHKRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYT 303 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C L H R+H K + C C K +S +L +H R + K +E Sbjct: 304 CNECGKVFNRLSTLARH-HRLHTGEKPYKCEECDKVFSRKSHLERHRRIHSGEKPYKCEE 362 Query: 387 ALDELCLMTREGKRQLL------YDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 + + + + Y C +C++ F+ + +H VH + P+ C CG Sbjct: 363 CCKVFSRKSNLERHRRIHTGEKPYKCKVCDKAFQRDSHLAQHQRVHTGEKPYKCNECGKT 422 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + +L +H R H Y C C K F L H Sbjct: 423 FGQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYH 460 Score = 90.5 bits (223), Expect = 9e-18 Identities = 58/188 (30%), Positives = 87/188 (46%), Gaps = 25/188 (13%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K +TC C KVF +L H R+HT EKPYKC +C + K++L H R H+GEK + Sbjct: 300 KPYTCNECGKVFNRLSTLARHHRLHTGEKPYKCEECDKVFSRKSHLERHRRIHSGEKPYK 359 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C K +L+ H R+H K + C+ C K + RD+H Q ++V Sbjct: 360 CEECCKVFSRKSNLERH-RRIHTGEKPYKCKVCDKAFQ---------RDSHLAQHQRV-- 407 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 G++ Y C+ C + F H +H + P+ C CG ++ + Sbjct: 408 ---------HTGEKP--YKCNECGKTFGQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSS 456 Query: 447 LELHVRKH 454 L H R H Sbjct: 457 LVYHHRLH 464 Score = 68.2 bits (165), Expect = 5e-11 Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 23/162 (14%) Query: 894 SDLQRHIW-AHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTL 952 S L W H K F+C + S LK H H EK CD+CGK F K L Sbjct: 146 SSLLTQKWEVHMREKSFECIQSFKSFNCSSLLKKHQIIHLEEKQCKCDVCGKVFNQKRYL 205 Query: 953 KSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 H+ HT + K +KC C T L H H KP+ C C + Sbjct: 206 ACHRRCHTGE-KPYKCNECGKTFGHNSSLFIHKALHTGEKPYECEEC----------DKV 254 Query: 1013 YNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVC--SFVYGT 1052 ++RK E + + TGE KC VC +F Y + Sbjct: 255 FSRKSHLERHKRIHTGEKP---------YKCKVCDEAFAYNS 287 Score = 54.3 bits (129), Expect = 7e-07 Identities = 25/57 (43%), Positives = 32/57 (56%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K + C C K F SL H R+HT EKPYKC +C + ++L H R H+GEK Sbjct: 412 KPYKCNECGKTFGQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYHHRLHSGEK 468 Score = 33.1 bits (74), Expect = 1.7 Identities = 16/59 (27%), Positives = 27/59 (45%) Query: 717 KVLNSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQC 775 KV + ++ + + +R+ +C CGK F +H R HT E Y C++C Sbjct: 389 KVCDKAFQRDSHLAQHQRVHTGEKPYKCNECGKTFGQTSSLIIHRRLHTGEKPYKCNEC 447 Score = 30.8 bits (68), Expect = 8.4 Identities = 13/30 (43%), Positives = 16/30 (53%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKP 298 K + C C K F SL H R+H+ EKP Sbjct: 440 KPYKCNECGKTFSQMSSLVYHHRLHSGEKP 469 >gi|57165432 zinc finger protein ZNF468 isoform 2 [Homo sapiens] Length = 522 Score = 136 bits (343), Expect = 1e-31 Identities = 91/308 (29%), Positives = 141/308 (45%), Gaps = 19/308 (6%) Query: 720 NSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSS 779 +SL KK L E+ +C+ CGK+F + + H R HT E Y C++C + Sbjct: 227 SSLLKKHQIIHLEEK------QCKCDVCGKVFNQKRYLACHRRCHTGEKPYKCNECGKTF 280 Query: 780 ITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSF 839 + L H +C + CD K L+ H ++HT ++ Y C VC+++F Sbjct: 281 GHNSSLFIHKALHTGEKPYEC--EECDKVFSRKSHLERHKRIHTG--EKPYKCKVCDEAF 336 Query: 840 SEDRLIKSH--IKTNHPEVSMSTISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNG 893 + + + H + T + + +V R L + G++ KC CD F + Sbjct: 337 AYNSYLAKHTILHTGEKPYTCNECGKVFNRLSTLARHHRLHTGEKPYKCEECDKVFSRK- 395 Query: 894 SDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLK 953 S L+RH H G KP+KC C KSNL+ H H+ EK + C +C K F+ L Sbjct: 396 SHLERHRRIHSGEKPYKCEECCKVFSRKSNLERHRRIHTGEKPYKCKVCDKAFQRDSHLA 455 Query: 954 SHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHY 1013 H+ +HT + K +KC C T Q L+ H H KP++C C + + SL H+ Sbjct: 456 QHQRVHTGE-KPYKCNECGKTFGQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYHH 514 Query: 1014 NRKHPNEE 1021 R H E+ Sbjct: 515 -RLHSGEK 521 Score = 121 bits (303), Expect = 5e-27 Identities = 79/251 (31%), Positives = 115/251 (45%), Gaps = 28/251 (11%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 ECE C K+F + H + H R HT E Y C C + + L +H I C Sbjct: 300 ECEECDKVFSRKSHLERHKRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYTCNE 359 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 G ++ L H ++HT ++ Y C C+K FS KSH++ + Sbjct: 360 CGKVFNRLST--LARHHRLHTG--EKPYKCEECDKVFSR----KSHLERH---------- 401 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 RR+ G++ KC C F + S+L+RH H G KP+KC +C+ A + S Sbjct: 402 ----RRIHS----GEKPYKCEECCKVFSRK-SNLERHRRIHTGEKPYKCKVCDKAFQRDS 452 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 +L H H+ EK + C+ CGK F +L H+ LHT + K +KC C T +Q L+ Sbjct: 453 HLAQHQRVHTGEKPYKCNECGKTFGQTSSLIIHRRLHTGE-KPYKCNECGKTFSQMSSLV 511 Query: 983 RHMEQHVSFKP 993 H H KP Sbjct: 512 YHHRLHSGEKP 522 Score = 119 bits (297), Expect = 2e-26 Identities = 89/304 (29%), Positives = 123/304 (40%), Gaps = 47/304 (15%) Query: 764 HTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHT 823 H RE + C Q S + LK+H I KC D C K L H + HT Sbjct: 209 HMREKSFECIQSFKSFNCSSLLKKHQIIHLEEKQCKC--DVCGKVFNQKRYLACHRRCHT 266 Query: 824 ALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCP 883 ++ Y C C K+F + + H K H G++ +C Sbjct: 267 G--EKPYKCNECGKTFGHNSSLFIH-KALH---------------------TGEKPYECE 302 Query: 884 YCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCG 943 CD F + S L+RH H G KP+KC +C+ A S L H H+ EK + C+ CG Sbjct: 303 ECDKVFSRK-SHLERHKRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYTCNECG 361 Query: 944 KKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSC 1003 K F TL H LHT + K +KC CD ++K L RH H KP++C C C Sbjct: 362 KVFNRLSTLARHHRLHTGE-KPYKCEECDKVFSRKSHLERHRRIHSGEKPYKCEEC---C 417 Query: 1004 NISGSLKRHYNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNK 1063 + ++RK E + + TGE KC VC + +H + Sbjct: 418 KV-------FSRKSNLERHRRIHTGEKP---------YKCKVCDKAFQRDSHLAQHQRVH 461 Query: 1064 HGLK 1067 G K Sbjct: 462 TGEK 465 Score = 107 bits (267), Expect = 7e-23 Identities = 71/219 (32%), Positives = 99/219 (45%), Gaps = 12/219 (5%) Query: 273 CEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYC 331 C+ C KVF K L H R HT EKPYKC +C ++L +H HTGEK + C+ C Sbjct: 245 CDVCGKVFNQKRYLACHRRCHTGEKPYKCNECGKTFGHNSSLFIHKALHTGEKPYECEEC 304 Query: 332 SFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKH--IRDAHDP----QDKKV 384 K HL+ H +R+H K + C+ C + ++ L KH + P + KV Sbjct: 305 DKVFSRKSHLERH-KRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYTCNECGKV 363 Query: 385 KEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKY 444 L L R + Y C C++ F + +RH +H + P+ CE C ++ Sbjct: 364 FNRLSTLARHHRLHTGEKPYKCEECDKVFSRKSHLERHRRIHSGEKPYKCEECCKVFSRK 423 Query: 445 QALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 LE H R H Y C VC K F L H + VH Sbjct: 424 SNLERHRRIHTGEKPYKCKVCDKAFQRDSHLAQH-QRVH 461 Score = 100 bits (248), Expect = 1e-20 Identities = 68/218 (31%), Positives = 96/218 (44%), Gaps = 11/218 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + CE C+KVF K L+ H RIHT EKPYKC C A A + L H HTGEK + Sbjct: 297 KPYECEECDKVFSRKSHLERHKRIHTGEKPYKCKVCDEAFAYNSYLAKHTILHTGEKPYT 356 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C L H R+H K + C C K +S +L +H R + K +E Sbjct: 357 CNECGKVFNRLSTLARH-HRLHTGEKPYKCEECDKVFSRKSHLERHRRIHSGEKPYKCEE 415 Query: 387 ALDELCLMTREGKRQLL------YDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 + + + + Y C +C++ F+ + +H VH + P+ C CG Sbjct: 416 CCKVFSRKSNLERHRRIHTGEKPYKCKVCDKAFQRDSHLAQHQRVHTGEKPYKCNECGKT 475 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + +L +H R H Y C C K F L H Sbjct: 476 FGQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYH 513 Score = 90.5 bits (223), Expect = 9e-18 Identities = 58/188 (30%), Positives = 87/188 (46%), Gaps = 25/188 (13%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K +TC C KVF +L H R+HT EKPYKC +C + K++L H R H+GEK + Sbjct: 353 KPYTCNECGKVFNRLSTLARHHRLHTGEKPYKCEECDKVFSRKSHLERHRRIHSGEKPYK 412 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C K +L+ H R+H K + C+ C K + RD+H Q ++V Sbjct: 413 CEECCKVFSRKSNLERH-RRIHTGEKPYKCKVCDKAFQ---------RDSHLAQHQRV-- 460 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 G++ Y C+ C + F H +H + P+ C CG ++ + Sbjct: 461 ---------HTGEKP--YKCNECGKTFGQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSS 509 Query: 447 LELHVRKH 454 L H R H Sbjct: 510 LVYHHRLH 517 Score = 68.2 bits (165), Expect = 5e-11 Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 23/162 (14%) Query: 894 SDLQRHIW-AHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTL 952 S L W H K F+C + S LK H H EK CD+CGK F K L Sbjct: 199 SSLLTQKWEVHMREKSFECIQSFKSFNCSSLLKKHQIIHLEEKQCKCDVCGKVFNQKRYL 258 Query: 953 KSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 H+ HT + K +KC C T L H H KP+ C C + Sbjct: 259 ACHRRCHTGE-KPYKCNECGKTFGHNSSLFIHKALHTGEKPYECEEC----------DKV 307 Query: 1013 YNRKHPNEEYANVGTGELAAEVLIQQGGLKCPVC--SFVYGT 1052 ++RK E + + TGE KC VC +F Y + Sbjct: 308 FSRKSHLERHKRIHTGEKP---------YKCKVCDEAFAYNS 340 Score = 54.3 bits (129), Expect = 7e-07 Identities = 25/57 (43%), Positives = 32/57 (56%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K + C C K F SL H R+HT EKPYKC +C + ++L H R H+GEK Sbjct: 465 KPYKCNECGKTFGQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYHHRLHSGEK 521 Score = 33.1 bits (74), Expect = 1.7 Identities = 16/59 (27%), Positives = 27/59 (45%) Query: 717 KVLNSLQKKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQC 775 KV + ++ + + +R+ +C CGK F +H R HT E Y C++C Sbjct: 442 KVCDKAFQRDSHLAQHQRVHTGEKPYKCNECGKTFGQTSSLIIHRRLHTGEKPYKCNEC 500 Score = 30.8 bits (68), Expect = 8.4 Identities = 13/30 (43%), Positives = 16/30 (53%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKP 298 K + C C K F SL H R+H+ EKP Sbjct: 493 KPYKCNECGKTFSQMSSLVYHHRLHSGEKP 522 >gi|48717241 zinc finger protein 425 [Homo sapiens] Length = 752 Score = 136 bits (342), Expect = 1e-31 Identities = 86/331 (25%), Positives = 140/331 (42%), Gaps = 37/331 (11%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CG+ F Y++ D H+R HT E + C +C+ S K LK H +Q +CP Sbjct: 388 CGECGRKFIYKIKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPE- 446 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C + ++AH ++H+ +++ + C C K F+ + H + + + Sbjct: 447 -CSRGFFWRNAMRAHQRLHS--EQKPFPCAECGKRFTRPSKLACHTRVHDRQ-------- 495 Query: 864 VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSN 923 + C C F + S L +H+ H KPF C+ C + R +++ Sbjct: 496 --------------KEFPCGECKKTFSQQ-SRLTQHLKVHTTEKPFSCAECGRSFRRRAH 540 Query: 924 LKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLR 983 L H HS E+ C C K F K ++K H+ +H D K F C CD T + QL Sbjct: 541 LTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHR-DEKPFACGECDKTYTHQSQLTE 599 Query: 984 HMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGTGE-------LAAEVLI 1036 H+ H KP++C C + + G+LK H + + ++ V G+ L + + Sbjct: 600 HLRLHSGEKPYQCPECEKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRV 659 Query: 1037 QQG--GLKCPVCSFVYGTKWEFNRHLKNKHG 1065 G +CP C Y + HL G Sbjct: 660 HSGEKPFQCPECDKSYCIRGSLKVHLYKHSG 690 Score = 124 bits (310), Expect = 7e-28 Identities = 81/290 (27%), Positives = 125/290 (43%), Gaps = 20/290 (6%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +R+ C CGK F H R H R+ + C +C + ++ L +H+ Sbjct: 461 QRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLTQHLKVH 520 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALD--KRSYSCPVCEKSFSEDRLIKSHIK 850 + C G ++ +AHL HT L + + CP C+KSFS +K H + Sbjct: 521 TTEKPFSCAECG------RSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQR 574 Query: 851 TNHPEVSMS--------TISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWA 902 + E + T L ++L G++ +CP C+ F G+ L+ H+ Sbjct: 575 MHRDEKPFACGECDKTYTHQSQLTEHLRLHS--GEKPYQCPECEKTFRLKGN-LKSHLLQ 631 Query: 903 HEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTAD 962 H G KPF C +C + + L H+ HS EK C C K + +G+LK H H+ + Sbjct: 632 HSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQCPECDKSYCIRGSLKVHLYKHSGE 691 Query: 963 GKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 + F+C C QK L H+ H +PF C C S G+LK H Sbjct: 692 -RPFQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTH 740 Score = 119 bits (299), Expect = 1e-26 Identities = 93/340 (27%), Positives = 129/340 (37%), Gaps = 70/340 (20%) Query: 723 QKKQMNTSLCERIRKVYGDL-------------ECEYCGKLFWYQVHFDMHVRTHTREHL 769 QKK+ S CE+ + G L C C K F Y+ + H+ H E Sbjct: 242 QKKRFQCSECEKSYFLKGSLVTHQVVHTGQRPYPCPECDKTFRYRANLKKHLCLHRGERP 301 Query: 770 YYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRS 829 + C +C + + + L H+ +CP CD K ++ HL H+ KR Sbjct: 302 FCCGECGRAFVQQCELTEHLRLHSGEKPFQCPQ--CDRCFRLKRGMKVHLTQHSG--KRP 357 Query: 830 YSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYF 889 + CP C +SFS +K+H +T+ E S C C F Sbjct: 358 FHCPECGRSFSRKAALKTHQRTHSEEKPFS----------------------CGECGRKF 395 Query: 890 MKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLK------------------------ 925 + L HI H G KPF C C + R K +LK Sbjct: 396 IYK-IKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWR 454 Query: 926 ----AHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQL 981 AH HS +K C CGK+F L H +H K+F C C T +Q+ +L Sbjct: 455 NAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQ-KEFPCGECKKTFSQQSRL 513 Query: 982 LRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 +H++ H + KPF CA C S L H R H EE Sbjct: 514 TQHLKVHTTEKPFSCAECGRSFRRRAHLTEH-TRLHSGEE 552 Score = 116 bits (290), Expect = 2e-25 Identities = 75/272 (27%), Positives = 115/272 (42%), Gaps = 34/272 (12%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILL---KC 800 C C K+F + H R+H++ L C Y + + +++ +L + Sbjct: 192 CYVCRKVFQVRRDLLKHKRSHSKSQL-----CRYPKYKNSSRGKSELRRTQRLLCQKKRF 246 Query: 801 PTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMST 860 C+ S K L H VHT +R Y CP C+K+F +K H+ + Sbjct: 247 QCSECEKSYFLKGSLVTHQVVHTG--QRPYPCPECDKTFRYRANLKKHLCLHR------- 297 Query: 861 ISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRS 920 G+R C C F++ +L H+ H G KPF+C C+ R Sbjct: 298 ---------------GERPFCCGECGRAFVQQ-CELTEHLRLHSGEKPFQCPQCDRCFRL 341 Query: 921 KSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQ 980 K +K H+ +HS ++ C CG+ F K LK+H+ H+ + K F C C K + Sbjct: 342 KRGMKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQRTHSEE-KPFSCGECGRKFIYKIK 400 Query: 981 LLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 L H+ H KPF C C+ S + SLK H Sbjct: 401 LDEHIRVHTGEKPFSCPECNKSFRLKRSLKAH 432 Score = 114 bits (285), Expect = 6e-25 Identities = 71/250 (28%), Positives = 107/250 (42%), Gaps = 28/250 (11%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 C CG+ F + H H R H+ E + C +C S K +K H C Sbjct: 528 CAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPFACGE- 586 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 CD + + +L HL++H+ ++ Y CP CEK+F +KSH+ + Sbjct: 587 -CDKTYTHQSQLTEHLRLHSG--EKPYQCPECEKTFRLKGNLKSHLLQHS---------- 633 Query: 864 VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSN 923 G++ C C F + L HI H G KPF+C C+ + + + Sbjct: 634 ------------GQKPFSCVMCGKSFTQQYR-LTEHIRVHSGEKPFQCPECDKSYCIRGS 680 Query: 924 LKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLR 983 LK H+ +HS E+ C CGK F K +LK+H LH+ + + F C C + L Sbjct: 681 LKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGE-RPFSCDECGRSFTYVGALKT 739 Query: 984 HMEQHVSFKP 993 H+ H KP Sbjct: 740 HIAVHAKEKP 749 Score = 103 bits (257), Expect = 1e-21 Identities = 90/379 (23%), Positives = 154/379 (40%), Gaps = 70/379 (18%) Query: 118 CSKCCRKFSNTRQLRKHICIIVLNLGEEE---GEAGNE--SDLELEKKCKEDDREKASKR 172 C +C + F L+KH+C L+ GE GE G EL + + EK + Sbjct: 276 CPECDKTFRYRANLKKHLC---LHRGERPFCCGECGRAFVQQCELTEHLRLHSGEKPFQC 332 Query: 173 PRSQKTEKVQKISGKEARQLSGAKKPIISVVLTAHEAIPGATKIVPVEAGPPETGATNSE 232 P+ + ++++ Q SG K+P PE G + S Sbjct: 333 PQCDRCFRLKRGMKVHLTQHSG-KRPFHC----------------------PECGRSFSR 369 Query: 233 TTSADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRI 292 + +K+ + ++ K F+C C + F +K L H+R+ Sbjct: 370 KAA----------------------LKTHQRTHSEEKPFSCGECGRKFIYKIKLDEHIRV 407 Query: 293 HTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKK 351 HT EKP+ CP+C+ + +K +L H +H G++ F C CS + ++ H +R+H + Sbjct: 408 HTGEKPFSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRAH-QRLHSE 466 Query: 352 IKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDK----KVKEALDELCLMTREGK---RQLL 403 K C C K+++ L H R HD Q + + K+ + +T+ K + Sbjct: 467 QKPFPCAECGKRFTRPSKLACHTR-VHDRQKEFPCGECKKTFSQQSRLTQHLKVHTTEKP 525 Query: 404 YDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH----PFVYV 459 + C C R F+ H +H + PF C C + +++ H R H PF Sbjct: 526 FSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPF--A 583 Query: 460 CAVCRKKFVSSIRLRTHIK 478 C C K + +L H++ Sbjct: 584 CGECDKTYTHQSQLTEHLR 602 Score = 101 bits (251), Expect = 5e-21 Identities = 58/193 (30%), Positives = 90/193 (46%), Gaps = 11/193 (5%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 F C C+K F +K S++ H R+H +EKP+ C +C ++ L HLR H+GEK + C Sbjct: 554 FQCPECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQCP 613 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEALD 389 C T KG+LK H+ + + C C K ++ L +HIR + + E Sbjct: 614 ECEKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQCPECDK 673 Query: 390 ELC--------LMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGA 441 C L G+R + C C + F + H+ +H + PF+C+ CG Sbjct: 674 SYCIRGSLKVHLYKHSGERP--FQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSF 731 Query: 442 TKYQALELHVRKH 454 T AL+ H+ H Sbjct: 732 TYVGALKTHIAVH 744 Score = 99.8 bits (247), Expect = 1e-20 Identities = 73/249 (29%), Positives = 109/249 (43%), Gaps = 21/249 (8%) Query: 828 RSYSCPVCEKSFSEDRLI----KSHIKT---NHPEVSMSTISEVLGRRVQLKGLIGKRAM 880 R YSC VC K F R + +SH K+ +P+ S+ + RR Q + L K+ Sbjct: 188 RCYSCYVCRKVFQVRRDLLKHKRSHSKSQLCRYPKYKNSSRGKSELRRTQ-RLLCQKKRF 246 Query: 881 KCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCD 940 +C C+ + GS L H H G +P+ C C+ R ++NLK H+ H E+ C Sbjct: 247 QCSECEKSYFLKGS-LVTHQVVHTGQRPYPCPECDKTFRYRANLKKHLCLHRGERPFCCG 305 Query: 941 MCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCH 1000 CG+ F + L H LH+ + K F+C CD K + H+ QH +PF C C Sbjct: 306 ECGRAFVQQCELTEHLRLHSGE-KPFQCPQCDRCFRLKRGMKVHLTQHSGKRPFHCPECG 364 Query: 1001 YSCNISGSLKRHYNRKHPNEEYANVGTG--------ELAAEVLIQQG--GLKCPVCSFVY 1050 S + +LK H R H E+ + G +L + + G CP C+ + Sbjct: 365 RSFSRKAALKTH-QRTHSEEKPFSCGECGRKFIYKIKLDEHIRVHTGEKPFSCPECNKSF 423 Query: 1051 GTKWEFNRH 1059 K H Sbjct: 424 RLKRSLKAH 432 Score = 93.2 bits (230), Expect = 1e-18 Identities = 64/222 (28%), Positives = 95/222 (42%), Gaps = 15/222 (6%) Query: 267 QLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK- 325 Q K F C C K + K SL H +HT ++PY CP+C +ANL HL H GE+ Sbjct: 242 QKKRFQCSECEKSYFLKGSLVTHQVVHTGQRPYPCPECDKTFRYRANLKKHLCLHRGERP 301 Query: 326 FACDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHI------RDAHD 378 F C C + + L H+ R+H K C C + + + + H+ R H Sbjct: 302 FCCGECGRAFVQQCELTEHL-RLHSGEKPFQCPQCDRCFRLKRGMKVHLTQHSGKRPFHC 360 Query: 379 PQDKKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCG 438 P+ + L R + + C C RKF ++ D H+ VH + PF+C C Sbjct: 361 PECGRSFSRKAALKTHQRTHSEEKPFSCGECGRKFIYKIKLDEHIRVHTGEKPFSCPECN 420 Query: 439 HGATKYQALEL----HVRKHPFVYVCAVCRKKFVSSIRLRTH 476 ++L+ H+ K PF C C + F +R H Sbjct: 421 KSFRLKRSLKAHGLQHIGKRPF--QCPECSRGFFWRNAMRAH 460 Score = 91.7 bits (226), Expect = 4e-18 Identities = 63/240 (26%), Positives = 101/240 (42%), Gaps = 13/240 (5%) Query: 254 YEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKAN 313 + M++ + ++ K F C C K F L H R+H +K + C +C + ++ Sbjct: 453 WRNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSR 512 Query: 314 LNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKH 372 L HL+ HT EK F+C C + + HL H + C C K +S ++ H Sbjct: 513 LTQHLKVHTTEKPFSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFH 572 Query: 373 IRDAHDPQD------KKVKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVH 426 R D + K +L R + Y C CE+ F+ + + H+L H Sbjct: 573 QRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQCPECEKTFRLKGNLKSHLLQH 632 Query: 427 GDKWPFACELCGHGATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRLRTHIKEVHG 482 + PF+C +CG T+ L H+R H PF C C K + L+ H+ + G Sbjct: 633 SGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPF--QCPECDKSYCIRGSLKVHLYKHSG 690 Score = 83.6 bits (205), Expect = 1e-15 Identities = 70/262 (26%), Positives = 109/262 (41%), Gaps = 26/262 (9%) Query: 118 CSKCCRKFSNTRQLRKHICIIVLNLGEEEGEAGNESDLELEKKCKEDDREKASKRPRSQK 177 C +C + FS +L +H+ + E C E R S R R+ Sbjct: 500 CGECKKTFSQQSRLTQHLKV---------------HTTEKPFSCAECGR---SFRRRAHL 541 Query: 178 TEKVQKISGKEARQLSGAKKPII-SVVLTAHEAIPGATKIVPVEAGPPETGATNSETTSA 236 TE + SG+E Q K + H+ + K P G + T+ + Sbjct: 542 TEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEK--PFACGECDKTYTHQSQLTE 599 Query: 237 DLVPRRGYQEYAIQQTP----YEQPMKSSRLGPTQLKIFTCEYCNKVFKFKHSLQAHLRI 292 L G + Y + + +KS L + K F+C C K F ++ L H+R+ Sbjct: 600 HLRLHSGEKPYQCPECEKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRV 659 Query: 293 HTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKK 351 H+ EKP++CP+C + I+ +L VHL KH+GE+ F C C L K LK H+ + Sbjct: 660 HSGEKPFQCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGE 719 Query: 352 IKQHCRFCKKKYSDVKNLIKHI 373 C C + ++ V L HI Sbjct: 720 RPFSCDECGRSFTYVGALKTHI 741 Score = 81.3 bits (199), Expect = 5e-15 Identities = 65/226 (28%), Positives = 99/226 (43%), Gaps = 15/226 (6%) Query: 265 PTQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGE 324 PT + ++C C KVF+ + L H R H+ + + P+ +S K+ L R + Sbjct: 184 PTGPRCYSCYVCRKVFQVRRDLLKHKRSHSKSQLCRYPKYKNSSRGKSELRRTQRLLCQK 243 Query: 325 K-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHI---RDAHDP 379 K F C C + KG L H + VH + + C C K + NL KH+ R Sbjct: 244 KRFQCSECEKSYFLKGSLVTH-QVVHTGQRPYPCPECDKTFRYRANLKKHLCLHRGERPF 302 Query: 380 QDKKVKEALDELCLMT---REGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACEL 436 + A + C +T R + + C C+R F+ + H+ H K PF C Sbjct: 303 CCGECGRAFVQQCELTEHLRLHSGEKPFQCPQCDRCFRLKRGMKVHLTQHSGKRPFHCPE 362 Query: 437 CGHGATKYQALELHVRKH----PFVYVCAVCRKKFVSSIRLRTHIK 478 CG ++ AL+ H R H PF C C +KF+ I+L HI+ Sbjct: 363 CGRSFSRKAALKTHQRTHSEEKPF--SCGECGRKFIYKIKLDEHIR 406 Score = 49.3 bits (116), Expect = 2e-05 Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 4/54 (7%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQC----SYASAIKANLNVHLRK 320 F C C K F K SL+AHL +H+ E+P+ C +C +Y A+K ++ VH ++ Sbjct: 694 FQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTHIAVHAKE 747 Score = 32.3 bits (72), Expect = 2.9 Identities = 10/28 (35%), Positives = 18/28 (64%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKP 298 F+C+ C + F + +L+ H+ +H EKP Sbjct: 722 FSCDECGRSFTYVGALKTHIAVHAKEKP 749 Score = 31.2 bits (69), Expect = 6.4 Identities = 14/47 (29%), Positives = 21/47 (44%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHV 789 +C CGK F + H+ H+ E + C +C S LK H+ Sbjct: 695 QCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTHI 741 >gi|221307571 zinc finger protein 234 [Homo sapiens] Length = 700 Score = 135 bits (341), Expect = 2e-31 Identities = 100/348 (28%), Positives = 142/348 (40%), Gaps = 35/348 (10%) Query: 728 NTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKR 787 N + +R+ +CE CGK F F H R HT E Y C C I + + Sbjct: 330 NLRIHQRVHTGEKPYKCEECGKCFIQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQA 389 Query: 788 HVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKS 847 H KC + C S K Q HL VHT ++ Y C VC K+F + +K Sbjct: 390 HQGVHTGEKPYKC--NECGKSFRMKIHYQVHLVVHTG--EKPYKCEVCGKAFRQSSYLKI 445 Query: 848 HIKTNHPEVSMSTISEVLGR------RVQLKGLI--GKRAMKCPYCDFYFMKNGSDLQRH 899 H+K + V E G+ R+Q+ LI G++ KC C F + +DL+ H Sbjct: 446 HLKAH--SVQKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRR-ADLKIH 502 Query: 900 IWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLH 959 H G KP+ C C S+L H HS EK C+ CGK F L++H+ +H Sbjct: 503 CRIHTGEKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEECGKSFSRSAHLQAHQKVH 562 Query: 960 TADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPN 1019 T + K +KC C L H H KP+ C C +H+++ Sbjct: 563 TGE-KPYKCGECGKGFKWSLNLDMHQRVHTGEKPYTCGEC----------GKHFSQASSL 611 Query: 1020 EEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 + + +V TGE KC VC V+ + H + G K Sbjct: 612 QLHQSVHTGEKP---------YKCDVCGKVFSRSSQLQYHRRVHTGEK 650 Score = 134 bits (338), Expect = 4e-31 Identities = 88/292 (30%), Positives = 127/292 (43%), Gaps = 20/292 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQC----HYSSITKNCLKRHVIQKHSNILL 798 +C CGK F ++H+ +H+ HT E Y C C SS K LK H +QK Sbjct: 401 KCNECGKSFRMKIHYQVHLVVHTGEKPYKCEVCGKAFRQSSYLKIHLKAHSVQKP----F 456 Query: 799 KCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEV 856 KC + C +LQ H +HT ++ Y C C K FS +K H I T Sbjct: 457 KC--EECGQGFNQSSRLQIHQLIHTG--EKPYKCEECGKGFSRRADLKIHCRIHTGEKPY 512 Query: 857 SMSTISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCS 912 + +V + L + G++ KC C F ++ + LQ H H G KP+KC Sbjct: 513 NCEECGKVFSQASHLLTHQRVHSGEKPFKCEECGKSFSRS-AHLQAHQKVHTGEKPYKCG 571 Query: 913 LCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCD 972 C + NL H H+ EK + C CGK F +L+ H+ +HT + K +KC VC Sbjct: 572 ECGKGFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQLHQSVHTGE-KPYKCDVCG 630 Query: 973 YTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYAN 1024 ++ QL H H KP++C C + +L H+ Y N Sbjct: 631 KVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSNLVSHHKIHAAGTFYEN 682 Score = 124 bits (312), Expect = 4e-28 Identities = 83/291 (28%), Positives = 123/291 (42%), Gaps = 27/291 (9%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 CE CG+ F + H H R HT E + C C + ++ L H + KC + Sbjct: 262 CEECGRAFIHASHLQEHQRIHTGEKPFKCDTCGKNFRRRSALNNHCMVHTGEKPYKC--E 319 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C L+ H +VHT ++ Y C C K F + ++H + + E + + Sbjct: 320 DCGKCFTCSSNLRIHQRVHTG--EKPYKCEECGKCFIQPSQFQAHRRIHTGEKPY--VCK 375 Query: 864 VLGRRVQLKGLI-------------GKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFK 910 V G KG I G++ KC C F Q H+ H G KP+K Sbjct: 376 VCG-----KGFIYSSSFQAHQGVHTGEKPYKCNECGKSFRMK-IHYQVHLVVHTGEKPYK 429 Query: 911 CSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTV 970 C +C A R S LK H+ HS +K C+ CG+ F L+ H+L+HT + K +KC Sbjct: 430 CEVCGKAFRQSSYLKIHLKAHSVQKPFKCEECGQGFNQSSRLQIHQLIHTGE-KPYKCEE 488 Query: 971 CDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 C +++ L H H KP+ C C + + L H R H E+ Sbjct: 489 CGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASHLLTH-QRVHSGEK 538 Score = 118 bits (295), Expect = 4e-26 Identities = 78/280 (27%), Positives = 120/280 (42%), Gaps = 28/280 (10%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +R+ V +C CGK F + +H + H+ E Y C +C + I + L+ H Sbjct: 223 QRVHTVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYNCEECGRAFIHASHLQEHQRIH 282 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 KC T G ++ + L H VHT ++ Y C C K F+ ++ H + + Sbjct: 283 TGEKPFKCDTCGKNFRR--RSALNNHCMVHTG--EKPYKCEDCGKCFTCSSNLRIHQRVH 338 Query: 853 HPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCS 912 G++ KC C F++ S Q H H G KP+ C Sbjct: 339 ----------------------TGEKPYKCEECGKCFIQ-PSQFQAHRRIHTGEKPYVCK 375 Query: 913 LCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCD 972 +C S+ +AH H+ EK + C+ CGK F+ K + H ++HT + K +KC VC Sbjct: 376 VCGKGFIYSSSFQAHQGVHTGEKPYKCNECGKSFRMKIHYQVHLVVHTGE-KPYKCEVCG 434 Query: 973 YTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 Q L H++ H KPF+C C N S L+ H Sbjct: 435 KAFRQSSYLKIHLKAHSVQKPFKCEECGQGFNQSSRLQIH 474 Score = 110 bits (274), Expect = 1e-23 Identities = 76/217 (35%), Positives = 100/217 (46%), Gaps = 28/217 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F CE C + F LQ H IHT EKPYKC +C + +A+L +H R HTGEK + Sbjct: 454 KPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYN 513 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C HL H +RVH K C C K +S R AH +KV Sbjct: 514 CEECGKVFSQASHLLTH-QRVHSGEKPFKCEECGKSFS---------RSAHLQAHQKV-- 561 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 G++ Y C C + FK L+ D H VH + P+ C CG ++ + Sbjct: 562 ---------HTGEKP--YKCGECGKGFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASS 610 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 L+LH H Y C VC K F S +L+ H + VH Sbjct: 611 LQLHQSVHTGEKPYKCDVCGKVFSRSSQLQYH-RRVH 646 Score = 102 bits (255), Expect = 2e-21 Identities = 59/212 (27%), Positives = 95/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F C+ C K F+ + +L H +HT EKPYKC C +NL +H R HTGEK + Sbjct: 286 KPFKCDTCGKNFRRRSALNNHCMVHTGEKPYKCEDCGKCFTCSSNLRIHQRVHTGEKPYK 345 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + + H R+H K + C+ C K + + H + H + Sbjct: 346 CEECGKCFIQPSQFQAH-RRIHTGEKPYVCKVCGKGFIYSSSFQAH-QGVHTGEKP---- 399 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 Y C+ C + F+ ++ H++VH + P+ CE+CG + Sbjct: 400 -----------------YKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEVCGKAFRQSSY 442 Query: 447 LELHVRKHPF--VYVCAVCRKKFVSSIRLRTH 476 L++H++ H + C C + F S RL+ H Sbjct: 443 LKIHLKAHSVQKPFKCEECGQGFNQSSRLQIH 474 Score = 100 bits (249), Expect = 9e-21 Identities = 73/279 (26%), Positives = 109/279 (39%), Gaps = 57/279 (20%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C+ K F +FD+H + H+ E + C +C S Sbjct: 149 QCDEYKKSFTDVFNFDLHQQLHSGEKSHTCDECGKSF----------------------- 185 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 C S L H +VH + ++ Y C VC K FS+ +++H + + E Sbjct: 186 --CYISA-----LHIHQRVH--MGEKCYKCDVCGKEFSQSSHLQTHQRVHTVE------- 229 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 + KC C F + S L H H G KP+ C C A S Sbjct: 230 ---------------KPFKCVECGKGFSRR-STLTVHCKLHSGEKPYNCEECGRAFIHAS 273 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 +L+ H H+ EK CD CGK F+ + L +H ++HT + K +KC C L Sbjct: 274 HLQEHQRIHTGEKPFKCDTCGKNFRRRSALNNHCMVHTGE-KPYKCEDCGKCFTCSSNLR 332 Query: 983 RHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 H H KP++C C C I S + + R H E+ Sbjct: 333 IHQRVHTGEKPYKCEECG-KCFIQPSQFQAHRRIHTGEK 370 Score = 98.6 bits (244), Expect = 3e-20 Identities = 64/212 (30%), Positives = 94/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C K F LQ H R+HT EKP+KC +C + ++ L VH + H+GEK + Sbjct: 202 KCYKCDVCGKEFSQSSHLQTHQRVHTVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYN 261 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + HL+ H +R+H K C C K + + + Sbjct: 262 CEECGRAFIHASHLQEH-QRIHTGEKPFKCDTCGKNF-------------------RRRS 301 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 AL+ C M G++ Y C C + F + H VH + P+ CE CG + Sbjct: 302 ALNNHC-MVHTGEKP--YKCEDCGKCFTCSSNLRIHQRVHTGEKPYKCEECGKCFIQPSQ 358 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + H R H YVC VC K F+ S + H Sbjct: 359 FQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAH 390 Score = 90.5 bits (223), Expect = 9e-18 Identities = 67/212 (31%), Positives = 95/212 (44%), Gaps = 20/212 (9%) Query: 259 KSSRLGPTQL-----KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKAN 313 +SSRL QL K + CE C K F + L+ H RIHT EKPY C +C + ++ Sbjct: 467 QSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASH 526 Query: 314 LNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIK 371 L H R H+GEK F C+ C + HL+ H ++VH K + C C K + NL Sbjct: 527 LLTHQRVHSGEKPFKCEECGKSFSRSAHLQAH-QKVHTGEKPYKCGECGKGFKWSLNLDM 585 Query: 372 HIRDAHDPQD--------KKVKEALD-ELCLMTREGKRQLLYDCHICERKFKNELDRDRH 422 H R H + K +A +L G++ Y C +C + F H Sbjct: 586 HQR-VHTGEKPYTCGECGKHFSQASSLQLHQSVHTGEKP--YKCDVCGKVFSRSSQLQYH 642 Query: 423 MLVHGDKWPFACELCGHGATKYQALELHVRKH 454 VH + P+ CE+CG + L H + H Sbjct: 643 RRVHTGEKPYKCEICGKRFSWRSNLVSHHKIH 674 Score = 85.9 bits (211), Expect = 2e-16 Identities = 62/220 (28%), Positives = 88/220 (40%), Gaps = 28/220 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K + C+ K F + H ++H+ EK + C +C + + L++H R H GEK Sbjct: 143 TGQKFYQCDEYKKSFTDVFNFDLHQQLHSGEKSHTCDECGKSFCYISALHIHQRVHMGEK 202 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 + CD C HL+ H +RVH K C C K +S L H + Sbjct: 203 CYKCDVCGKEFSQSSHLQTH-QRVHTVEKPFKCVECGKGFSRRSTLTVHCK--------- 252 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 G++ Y+C C R F + H +H + PF C+ CG + Sbjct: 253 -----------LHSGEKP--YNCEECGRAFIHASHLQEHQRIHTGEKPFKCDTCGKNFRR 299 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 AL H H Y C C K F S LR H + VH Sbjct: 300 RSALNNHCMVHTGEKPYKCEDCGKCFTCSSNLRIH-QRVH 338 Score = 53.5 bits (127), Expect = 1e-06 Identities = 24/58 (41%), Positives = 31/58 (53%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEKF 326 K + C+ C KVF LQ H R+HT EKPYKC C + ++NL H + H F Sbjct: 622 KPYKCDVCGKVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSNLVSHHKIHAAGTF 679 Score = 38.1 bits (87), Expect = 0.053 Identities = 32/127 (25%), Positives = 44/127 (34%), Gaps = 32/127 (25%) Query: 724 KKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKN 783 K +N + +R+ C CGK F +H HT E Y C C Sbjct: 578 KWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQLHQSVHTGEKPYKCDVC-------- 629 Query: 784 CLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDR 843 V + S +LQ H +VHT ++ Y C +C K FS Sbjct: 630 ---GKVFSRSS-------------------QLQYHRRVHTG--EKPYKCEICGKRFSWRS 665 Query: 844 LIKSHIK 850 + SH K Sbjct: 666 NLVSHHK 672 >gi|24307913 zinc finger protein 234 [Homo sapiens] Length = 700 Score = 135 bits (341), Expect = 2e-31 Identities = 100/348 (28%), Positives = 142/348 (40%), Gaps = 35/348 (10%) Query: 728 NTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKR 787 N + +R+ +CE CGK F F H R HT E Y C C I + + Sbjct: 330 NLRIHQRVHTGEKPYKCEECGKCFIQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQA 389 Query: 788 HVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKS 847 H KC + C S K Q HL VHT ++ Y C VC K+F + +K Sbjct: 390 HQGVHTGEKPYKC--NECGKSFRMKIHYQVHLVVHTG--EKPYKCEVCGKAFRQSSYLKI 445 Query: 848 HIKTNHPEVSMSTISEVLGR------RVQLKGLI--GKRAMKCPYCDFYFMKNGSDLQRH 899 H+K + V E G+ R+Q+ LI G++ KC C F + +DL+ H Sbjct: 446 HLKAH--SVQKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRR-ADLKIH 502 Query: 900 IWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLH 959 H G KP+ C C S+L H HS EK C+ CGK F L++H+ +H Sbjct: 503 CRIHTGEKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEECGKSFSRSAHLQAHQKVH 562 Query: 960 TADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPN 1019 T + K +KC C L H H KP+ C C +H+++ Sbjct: 563 TGE-KPYKCGECGKGFKWSLNLDMHQRVHTGEKPYTCGEC----------GKHFSQASSL 611 Query: 1020 EEYANVGTGELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 + + +V TGE KC VC V+ + H + G K Sbjct: 612 QLHQSVHTGEKP---------YKCDVCGKVFSRSSQLQYHRRVHTGEK 650 Score = 134 bits (338), Expect = 4e-31 Identities = 88/292 (30%), Positives = 127/292 (43%), Gaps = 20/292 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQC----HYSSITKNCLKRHVIQKHSNILL 798 +C CGK F ++H+ +H+ HT E Y C C SS K LK H +QK Sbjct: 401 KCNECGKSFRMKIHYQVHLVVHTGEKPYKCEVCGKAFRQSSYLKIHLKAHSVQKP----F 456 Query: 799 KCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEV 856 KC + C +LQ H +HT ++ Y C C K FS +K H I T Sbjct: 457 KC--EECGQGFNQSSRLQIHQLIHTG--EKPYKCEECGKGFSRRADLKIHCRIHTGEKPY 512 Query: 857 SMSTISEVLGRRVQL----KGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCS 912 + +V + L + G++ KC C F ++ + LQ H H G KP+KC Sbjct: 513 NCEECGKVFSQASHLLTHQRVHSGEKPFKCEECGKSFSRS-AHLQAHQKVHTGEKPYKCG 571 Query: 913 LCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCD 972 C + NL H H+ EK + C CGK F +L+ H+ +HT + K +KC VC Sbjct: 572 ECGKGFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQLHQSVHTGE-KPYKCDVCG 630 Query: 973 YTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYAN 1024 ++ QL H H KP++C C + +L H+ Y N Sbjct: 631 KVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSNLVSHHKIHAAGTFYEN 682 Score = 124 bits (312), Expect = 4e-28 Identities = 83/291 (28%), Positives = 123/291 (42%), Gaps = 27/291 (9%) Query: 744 CEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTD 803 CE CG+ F + H H R HT E + C C + ++ L H + KC + Sbjct: 262 CEECGRAFIHASHLQEHQRIHTGEKPFKCDTCGKNFRRRSALNNHCMVHTGEKPYKC--E 319 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C L+ H +VHT ++ Y C C K F + ++H + + E + + Sbjct: 320 DCGKCFTCSSNLRIHQRVHTG--EKPYKCEECGKCFIQPSQFQAHRRIHTGEKPY--VCK 375 Query: 864 VLGRRVQLKGLI-------------GKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFK 910 V G KG I G++ KC C F Q H+ H G KP+K Sbjct: 376 VCG-----KGFIYSSSFQAHQGVHTGEKPYKCNECGKSFRMK-IHYQVHLVVHTGEKPYK 429 Query: 911 CSLCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTV 970 C +C A R S LK H+ HS +K C+ CG+ F L+ H+L+HT + K +KC Sbjct: 430 CEVCGKAFRQSSYLKIHLKAHSVQKPFKCEECGQGFNQSSRLQIHQLIHTGE-KPYKCEE 488 Query: 971 CDYTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 C +++ L H H KP+ C C + + L H R H E+ Sbjct: 489 CGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASHLLTH-QRVHSGEK 538 Score = 118 bits (295), Expect = 4e-26 Identities = 78/280 (27%), Positives = 120/280 (42%), Gaps = 28/280 (10%) Query: 733 ERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQK 792 +R+ V +C CGK F + +H + H+ E Y C +C + I + L+ H Sbjct: 223 QRVHTVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYNCEECGRAFIHASHLQEHQRIH 282 Query: 793 HSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTN 852 KC T G ++ + L H VHT ++ Y C C K F+ ++ H + + Sbjct: 283 TGEKPFKCDTCGKNFRR--RSALNNHCMVHTG--EKPYKCEDCGKCFTCSSNLRIHQRVH 338 Query: 853 HPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCS 912 G++ KC C F++ S Q H H G KP+ C Sbjct: 339 ----------------------TGEKPYKCEECGKCFIQ-PSQFQAHRRIHTGEKPYVCK 375 Query: 913 LCEYATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCD 972 +C S+ +AH H+ EK + C+ CGK F+ K + H ++HT + K +KC VC Sbjct: 376 VCGKGFIYSSSFQAHQGVHTGEKPYKCNECGKSFRMKIHYQVHLVVHTGE-KPYKCEVCG 434 Query: 973 YTAAQKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH 1012 Q L H++ H KPF+C C N S L+ H Sbjct: 435 KAFRQSSYLKIHLKAHSVQKPFKCEECGQGFNQSSRLQIH 474 Score = 110 bits (274), Expect = 1e-23 Identities = 76/217 (35%), Positives = 100/217 (46%), Gaps = 28/217 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F CE C + F LQ H IHT EKPYKC +C + +A+L +H R HTGEK + Sbjct: 454 KPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYN 513 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C HL H +RVH K C C K +S R AH +KV Sbjct: 514 CEECGKVFSQASHLLTH-QRVHSGEKPFKCEECGKSFS---------RSAHLQAHQKV-- 561 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 G++ Y C C + FK L+ D H VH + P+ C CG ++ + Sbjct: 562 ---------HTGEKP--YKCGECGKGFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASS 610 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 L+LH H Y C VC K F S +L+ H + VH Sbjct: 611 LQLHQSVHTGEKPYKCDVCGKVFSRSSQLQYH-RRVH 646 Score = 102 bits (255), Expect = 2e-21 Identities = 59/212 (27%), Positives = 95/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K F C+ C K F+ + +L H +HT EKPYKC C +NL +H R HTGEK + Sbjct: 286 KPFKCDTCGKNFRRRSALNNHCMVHTGEKPYKCEDCGKCFTCSSNLRIHQRVHTGEKPYK 345 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + + H R+H K + C+ C K + + H + H + Sbjct: 346 CEECGKCFIQPSQFQAH-RRIHTGEKPYVCKVCGKGFIYSSSFQAH-QGVHTGEKP---- 399 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 Y C+ C + F+ ++ H++VH + P+ CE+CG + Sbjct: 400 -----------------YKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEVCGKAFRQSSY 442 Query: 447 LELHVRKHPF--VYVCAVCRKKFVSSIRLRTH 476 L++H++ H + C C + F S RL+ H Sbjct: 443 LKIHLKAHSVQKPFKCEECGQGFNQSSRLQIH 474 Score = 100 bits (249), Expect = 9e-21 Identities = 73/279 (26%), Positives = 109/279 (39%), Gaps = 57/279 (20%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +C+ K F +FD+H + H+ E + C +C S Sbjct: 149 QCDEYKKSFTDVFNFDLHQQLHSGEKSHTCDECGKSF----------------------- 185 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTIS 862 C S L H +VH + ++ Y C VC K FS+ +++H + + E Sbjct: 186 --CYISA-----LHIHQRVH--MGEKCYKCDVCGKEFSQSSHLQTHQRVHTVE------- 229 Query: 863 EVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKS 922 + KC C F + S L H H G KP+ C C A S Sbjct: 230 ---------------KPFKCVECGKGFSRR-STLTVHCKLHSGEKPYNCEECGRAFIHAS 273 Query: 923 NLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLL 982 +L+ H H+ EK CD CGK F+ + L +H ++HT + K +KC C L Sbjct: 274 HLQEHQRIHTGEKPFKCDTCGKNFRRRSALNNHCMVHTGE-KPYKCEDCGKCFTCSSNLR 332 Query: 983 RHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 H H KP++C C C I S + + R H E+ Sbjct: 333 IHQRVHTGEKPYKCEECG-KCFIQPSQFQAHRRIHTGEK 370 Score = 98.6 bits (244), Expect = 3e-20 Identities = 64/212 (30%), Positives = 94/212 (44%), Gaps = 27/212 (12%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C+ C K F LQ H R+HT EKP+KC +C + ++ L VH + H+GEK + Sbjct: 202 KCYKCDVCGKEFSQSSHLQTHQRVHTVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYN 261 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ C + HL+ H +R+H K C C K + + + Sbjct: 262 CEECGRAFIHASHLQEH-QRIHTGEKPFKCDTCGKNF-------------------RRRS 301 Query: 387 ALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQA 446 AL+ C M G++ Y C C + F + H VH + P+ CE CG + Sbjct: 302 ALNNHC-MVHTGEKP--YKCEDCGKCFTCSSNLRIHQRVHTGEKPYKCEECGKCFIQPSQ 358 Query: 447 LELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + H R H YVC VC K F+ S + H Sbjct: 359 FQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAH 390 Score = 90.5 bits (223), Expect = 9e-18 Identities = 67/212 (31%), Positives = 95/212 (44%), Gaps = 20/212 (9%) Query: 259 KSSRLGPTQL-----KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKAN 313 +SSRL QL K + CE C K F + L+ H RIHT EKPY C +C + ++ Sbjct: 467 QSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASH 526 Query: 314 LNVHLRKHTGEK-FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIK 371 L H R H+GEK F C+ C + HL+ H ++VH K + C C K + NL Sbjct: 527 LLTHQRVHSGEKPFKCEECGKSFSRSAHLQAH-QKVHTGEKPYKCGECGKGFKWSLNLDM 585 Query: 372 HIRDAHDPQD--------KKVKEALD-ELCLMTREGKRQLLYDCHICERKFKNELDRDRH 422 H R H + K +A +L G++ Y C +C + F H Sbjct: 586 HQR-VHTGEKPYTCGECGKHFSQASSLQLHQSVHTGEKP--YKCDVCGKVFSRSSQLQYH 642 Query: 423 MLVHGDKWPFACELCGHGATKYQALELHVRKH 454 VH + P+ CE+CG + L H + H Sbjct: 643 RRVHTGEKPYKCEICGKRFSWRSNLVSHHKIH 674 Score = 85.9 bits (211), Expect = 2e-16 Identities = 62/220 (28%), Positives = 88/220 (40%), Gaps = 28/220 (12%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T K + C+ K F + H ++H+ EK + C +C + + L++H R H GEK Sbjct: 143 TGQKFYQCDEYKKSFTDVFNFDLHQQLHSGEKSHTCDECGKSFCYISALHIHQRVHMGEK 202 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQ-HCRFCKKKYSDVKNLIKHIRDAHDPQDKK 383 + CD C HL+ H +RVH K C C K +S L H + Sbjct: 203 CYKCDVCGKEFSQSSHLQTH-QRVHTVEKPFKCVECGKGFSRRSTLTVHCK--------- 252 Query: 384 VKEALDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATK 443 G++ Y+C C R F + H +H + PF C+ CG + Sbjct: 253 -----------LHSGEKP--YNCEECGRAFIHASHLQEHQRIHTGEKPFKCDTCGKNFRR 299 Query: 444 YQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 AL H H Y C C K F S LR H + VH Sbjct: 300 RSALNNHCMVHTGEKPYKCEDCGKCFTCSSNLRIH-QRVH 338 Score = 53.5 bits (127), Expect = 1e-06 Identities = 24/58 (41%), Positives = 31/58 (53%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEKF 326 K + C+ C KVF LQ H R+HT EKPYKC C + ++NL H + H F Sbjct: 622 KPYKCDVCGKVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSNLVSHHKIHAAGTF 679 Score = 38.1 bits (87), Expect = 0.053 Identities = 32/127 (25%), Positives = 44/127 (34%), Gaps = 32/127 (25%) Query: 724 KKQMNTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKN 783 K +N + +R+ C CGK F +H HT E Y C C Sbjct: 578 KWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQLHQSVHTGEKPYKCDVC-------- 629 Query: 784 CLKRHVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDR 843 V + S +LQ H +VHT ++ Y C +C K FS Sbjct: 630 ---GKVFSRSS-------------------QLQYHRRVHTG--EKPYKCEICGKRFSWRS 665 Query: 844 LIKSHIK 850 + SH K Sbjct: 666 NLVSHHK 672 >gi|209954795 zinc finger protein 761 [Homo sapiens] Length = 746 Score = 135 bits (341), Expect = 2e-31 Identities = 97/340 (28%), Positives = 141/340 (41%), Gaps = 21/340 (6%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +CE C K F ++ + H HT E Y C++C + K+ L RH KC Sbjct: 299 KCEECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNE 358 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSH--IKTNHPEVSMST 860 G +S K L H ++HT ++ Y C C K+FS + H + T Sbjct: 359 CGKTFS--HKSSLTCHHRLHTG--EKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYKCEE 414 Query: 861 ISEVLGRR----VQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 + R + K A KC C F + S L H H G +P+KC C+ Sbjct: 415 CDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSS-LTCHRRRHTGEQPYKCEECDK 473 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A R KSNL+ H H+ EK + C+ CGK F K L H LHT + K +KC C T + Sbjct: 474 AFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGE-KAYKCNECGKTFS 532 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRH---------YNRKHPNEEYANVGT 1027 K L H H KP++C C + N +LKRH Y + ++ Y+ Sbjct: 533 WKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSN 592 Query: 1028 GELAAEVLIQQGGLKCPVCSFVYGTKWEFNRHLKNKHGLK 1067 E+ ++ ++ KC C + H + G K Sbjct: 593 LEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEK 632 Score = 131 bits (330), Expect = 3e-30 Identities = 87/285 (30%), Positives = 127/285 (44%), Gaps = 13/285 (4%) Query: 743 ECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPT 802 +CE C K F ++ + + H R HT E Y C++C + K+ L H KC Sbjct: 467 KCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNE 526 Query: 803 DGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEV------ 856 G +S K L H ++H+ ++ Y C C K+F++ +K H + + E Sbjct: 527 CGKTFSW--KSSLTCHRRLHSG--EKPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCED 582 Query: 857 SMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEY 916 S S + K + KC C F + S L H H G KP+KC C+ Sbjct: 583 SDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSS-LTCHRRLHTGEKPYKCEECDK 641 Query: 917 ATRSKSNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAA 976 A R KSNL+ H H+ EK + C+ CGK F K H LHT + K +KC C + Sbjct: 642 AFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGE-KPYKCNECGKNFS 700 Query: 977 QKPQLLRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEE 1021 QK L+ H H KP++C C + + +L H R H E+ Sbjct: 701 QKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCH-RRLHTGEK 744 Score = 113 bits (283), Expect = 1e-24 Identities = 84/282 (29%), Positives = 118/282 (41%), Gaps = 43/282 (15%) Query: 748 GKLFWYQVHFDMHVRTHTREHLYYCSQC----HYSSITKNCLKRHVIQKHSNILLKCPTD 803 G FW H RE + C++ +YSS+ + H+ K+ KC D Sbjct: 193 GNNFWNSSLLTQKQEVHMREKSFQCNESGKAFNYSSLLRKHQIIHLADKY-----KC--D 245 Query: 804 GCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISE 863 C K L H + HT + Y C C K+FS+ + H Sbjct: 246 VCGKLFNQKRNLACHRRCHTG--ENPYKCNECGKTFSQTSSLTCH--------------- 288 Query: 864 VLGRRVQLKGLIGKRAMKCPYCD--FYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSK 921 RR+ G++ KC CD F+F S L+RH H KP+KC+ C R K Sbjct: 289 ---RRLH----TGEKPYKCEECDKAFHFK---SILERHRIIHTEEKPYKCNECGKTFRQK 338 Query: 922 SNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQL 981 S L H H+ EK + C+ CGK F K +L H LHT + K +KC C T + K L Sbjct: 339 SILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGE-KPYKCNECGKTFSHKSSL 397 Query: 982 LRHMEQHVSFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYA 1023 H H KP++C C + + + + H RK E+ A Sbjct: 398 TCHRRLHTGEKPYKCEECDKAYSFRSNFEIH--RKIHTEDNA 437 Score = 110 bits (274), Expect = 1e-23 Identities = 80/268 (29%), Positives = 116/268 (43%), Gaps = 17/268 (6%) Query: 225 ETGATNSETTSADLVPR--RGYQEYAIQQTP----YEQPMKSSRLGPTQLKIFTCEYCNK 278 E G T S+T+S R G + Y ++ ++ ++ R+ T+ K + C C K Sbjct: 274 ECGKTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECGK 333 Query: 279 VFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLS 337 F+ K L H R+HT EKPYKC +C + K++L H R HTGEK + C+ C T Sbjct: 334 TFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSH 393 Query: 338 KGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEA------LDE 390 K L H R+H K + C C K YS N H + + K E Sbjct: 394 KSSLTCH-RRLHTGEKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSS 452 Query: 391 LCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELH 450 L R + Y C C++ F+ + + +RH +H + P+ C CG ++ L H Sbjct: 453 LTCHRRRHTGEQPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCH 512 Query: 451 VRKH--PFVYVCAVCRKKFVSSIRLRTH 476 R H Y C C K F L H Sbjct: 513 HRLHTGEKAYKCNECGKTFSWKSSLTCH 540 Score = 101 bits (252), Expect = 4e-21 Identities = 72/260 (27%), Positives = 105/260 (40%), Gaps = 36/260 (13%) Query: 815 LQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMSTISEVLGRRVQLKGL 874 L+ H +H A DK Y C VC K F++ R + H + + Sbjct: 230 LRKHQIIHLA-DK--YKCDVCGKLFNQKRNLACHRRCH---------------------- 264 Query: 875 IGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSKSNLKAHMNRHSTE 934 G+ KC C F + S L H H G KP+KC C+ A KS L+ H H+ E Sbjct: 265 TGENPYKCNECGKTFSQTSS-LTCHRRLHTGEKPYKCEECDKAFHFKSILERHRIIHTEE 323 Query: 935 KTHLCDMCGKKFKSKGTLKSHKLLHTADGKQFKCTVCDYTAAQKPQLLRHMEQHVSFKPF 994 K + C+ CGK F+ K L H LHT + K +KC C T + K L H H KP+ Sbjct: 324 KPYKCNECGKTFRQKSILTRHHRLHTGE-KPYKCNECGKTFSHKSSLTCHHRLHTGEKPY 382 Query: 995 RCAHCHYSCNISGSLKRH---------YNRKHPNEEYANVGTGELAAEVLIQQGGLKCPV 1045 +C C + + SL H Y + ++ Y+ E+ ++ + KC Sbjct: 383 KCNECGKTFSHKSSLTCHRRLHTGEKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNE 442 Query: 1046 CSFVYGTKWEFNRHLKNKHG 1065 C + H + G Sbjct: 443 CGKTFSRTSSLTCHRRRHTG 462 Score = 101 bits (252), Expect = 4e-21 Identities = 65/215 (30%), Positives = 98/215 (45%), Gaps = 28/215 (13%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 + CE C+K F+FK +L+ H RIHT EKPYKC +C + K+ L H R HTGEK + C+ Sbjct: 466 YKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCN 525 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEAL 388 C T K L H R+H K + C+ C K ++ L +H R H ++ Sbjct: 526 ECGKTFSWKSSLTCH-RRLHSGEKPYKCKECGKTFNQQLTLKRH-RRLHSGENP------ 577 Query: 389 DELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALE 448 Y C ++ + + + + H +H ++ P+ C CG ++ +L Sbjct: 578 ---------------YKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLT 622 Query: 449 LHVRKH--PFVYVCAVCRKKFVSSIRLRTHIKEVH 481 H R H Y C C K F L H + +H Sbjct: 623 CHRRLHTGEKPYKCEECDKAFRVKSNLEGH-RRIH 656 Score = 94.0 bits (232), Expect = 8e-19 Identities = 77/268 (28%), Positives = 109/268 (40%), Gaps = 17/268 (6%) Query: 225 ETGATNSETTSADLVPRR--GYQEYAIQQTP----YEQPMKSSRLGPTQLKIFTCEYCNK 278 E G T S T+S RR G Q Y ++ ++ ++ R T K + C C K Sbjct: 442 ECGKTFSRTSSLTCHRRRHTGEQPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGK 501 Query: 279 VFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACDYCSFTCLS 337 F K L H R+HT EK YKC +C + K++L H R H+GEK + C C T Sbjct: 502 TFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLHSGEKPYKCKECGKTFNQ 561 Query: 338 KGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEA------LDE 390 + LK H R+H + C K YS NL H + + K E Sbjct: 562 QLTLKRH-RRLHSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSS 620 Query: 391 LCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELH 450 L R + Y C C++ F+ + + + H +H + P+ C CG ++ H Sbjct: 621 LTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICH 680 Query: 451 VRKH--PFVYVCAVCRKKFVSSIRLRTH 476 R H Y C C K F L H Sbjct: 681 HRLHTGEKPYKCNECGKNFSQKSSLICH 708 Score = 91.3 bits (225), Expect = 5e-18 Identities = 62/218 (28%), Positives = 96/218 (44%), Gaps = 11/218 (5%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FA 327 K + C C K F +K SL H R+H+ EKPYKC +C + L H R H+GE + Sbjct: 520 KAYKCNECGKTFSWKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENPYK 579 Query: 328 CDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKE 386 C+ K +L++H +++H + + C C K +S +L H R + K +E Sbjct: 580 CEDSDKAYSFKSNLEIH-QKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEE 638 Query: 387 ALDELCLMTR-EGKRQL-----LYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHG 440 + + EG R++ Y C+ C + F + H +H + P+ C CG Sbjct: 639 CDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNECGKN 698 Query: 441 ATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 ++ +L H R H Y C C K F L H Sbjct: 699 FSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCH 736 Score = 89.4 bits (220), Expect = 2e-17 Identities = 61/219 (27%), Positives = 89/219 (40%), Gaps = 17/219 (7%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 + C+ C K+F K +L H R HT E PYKC +C + ++L H R HTGEK + C+ Sbjct: 242 YKCDVCGKLFNQKRNLACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLHTGEKPYKCE 301 Query: 330 YCS----FTCLSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDAHDPQDKKVK 385 C F + + H +H E K C C K + L +H R + K Sbjct: 302 ECDKAFHFKSILERHRIIHTEEKPYK----CNECGKTFRQKSILTRHHRLHTGEKPYKCN 357 Query: 386 EA------LDELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGH 439 E L R + Y C+ C + F ++ H +H + P+ CE C Sbjct: 358 ECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYKCEECDK 417 Query: 440 GATKYQALELHVRKH--PFVYVCAVCRKKFVSSIRLRTH 476 + E+H + H Y C C K F + L H Sbjct: 418 AYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCH 456 Score = 84.3 bits (207), Expect = 6e-16 Identities = 56/186 (30%), Positives = 81/186 (43%), Gaps = 25/186 (13%) Query: 271 FTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK-FACD 329 + CE +K + FK +L+ H +IHT E PYKC +C + ++L H R HTGEK + C+ Sbjct: 578 YKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCE 637 Query: 330 YCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEAL 388 C K +L+ H R+H K + C C K +S I H R Sbjct: 638 ECDKAFRVKSNLEGH-RRIHTGEKPYKCNECGKTFSRKSYFICHHR-------------- 682 Query: 389 DELCLMTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALE 448 L T E Y C+ C + F + H +H + P+ C CG ++ L Sbjct: 683 ----LHTGEKP----YKCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLT 734 Query: 449 LHVRKH 454 H R H Sbjct: 735 CHRRLH 740 Score = 82.4 bits (202), Expect = 2e-15 Identities = 45/111 (40%), Positives = 58/111 (52%), Gaps = 3/111 (2%) Query: 266 TQLKIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 T+ + C C K F SL H R+HT EKPYKC +C A +K+NL H R HTGEK Sbjct: 601 TEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEK 660 Query: 326 -FACDYCSFTCLSKGHLKVHIERVHKKIKQH-CRFCKKKYSDVKNLIKHIR 374 + C+ C T K + H R+H K + C C K +S +LI H R Sbjct: 661 PYKCNECGKTFSRKSYFICH-HRLHTGEKPYKCNECGKNFSQKSSLICHHR 710 Score = 63.5 bits (153), Expect = 1e-09 Identities = 29/57 (50%), Positives = 34/57 (59%) Query: 269 KIFTCEYCNKVFKFKHSLQAHLRIHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEK 325 K + C C K F K SL H R+HT EKPYKC +C + K+NL H R HTGEK Sbjct: 688 KPYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCHRRLHTGEK 744 Score = 62.4 bits (150), Expect = 3e-09 Identities = 48/194 (24%), Positives = 75/194 (38%), Gaps = 10/194 (5%) Query: 292 IHTNEKPYKCPQCSYASAIKANLNVHLRKHTGEKFACDYCSFTCLSKGHLKVHIERVHKK 351 +H EK ++C + A + L H H +K+ CD C K +L H R H Sbjct: 208 VHMREKSFQCNESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACH-RRCHTG 266 Query: 352 IKQH-CRFCKKKYSDVKNLIKHIRDAHDPQDKKVKEALDELCLMTREGKRQLL------Y 404 + C C K +S +L H R + K +E + + +++ Y Sbjct: 267 ENPYKCNECGKTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSILERHRIIHTEEKPY 326 Query: 405 DCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHVRKH--PFVYVCAV 462 C+ C + F+ + RH +H + P+ C CG + +L H R H Y C Sbjct: 327 KCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCNE 386 Query: 463 CRKKFVSSIRLRTH 476 C K F L H Sbjct: 387 CGKTFSHKSSLTCH 400 Score = 62.4 bits (150), Expect = 3e-09 Identities = 53/208 (25%), Positives = 74/208 (35%), Gaps = 55/208 (26%) Query: 728 NTSLCERIRKVYGDLECEYCGKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKR 787 N + ++I +C CGK F H R HT E Y C + Sbjct: 592 NLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEE------------- 638 Query: 788 HVIQKHSNILLKCPTDGCDYSTPDKYKLQAHLKVHTALDKRSYSCPVCEKSFSEDRLIKS 847 CD + K L+ H ++HT ++ Y C C K+FS KS Sbjct: 639 -----------------CDKAFRVKSNLEGHRRIHTG--EKPYKCNECGKTFSR----KS 675 Query: 848 HIKTNHPEVSMSTISEVLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVK 907 + +H + G++ KC C F + S L H H G K Sbjct: 676 YFICHH------------------RLHTGEKPYKCNECGKNFSQK-SSLICHHRLHTGEK 716 Query: 908 PFKCSLCEYATRSKSNLKAHMNRHSTEK 935 P+KC+ C KSNL H H+ EK Sbjct: 717 PYKCNECGKTFSQKSNLTCHRRLHTGEK 744 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.130 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 52,375,580 Number of Sequences: 37866 Number of extensions: 2654792 Number of successful extensions: 76105 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1050 Number of HSP's successfully gapped in prelim test: 147 Number of HSP's that attempted gapping in prelim test: 10668 Number of HSP's gapped (non-prelim): 19268 length of query: 1243 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1129 effective length of database: 13,930,794 effective search space: 15727866426 effective search space used: 15727866426 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.