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Search of human proteins with 46391075
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46391075 hypothetical protein LOC79949 [Homo sapiens]
(363 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46391075 hypothetical protein LOC79949 [Homo sapiens] 729 0.0
gi|126091130 Gab3 protein isoform 1 [Homo sapiens] 47 3e-05
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa... 45 1e-04
gi|83716021 GRB2-associated binding protein family, member 4 [Ho... 44 2e-04
gi|18079323 Gab3 protein isoform 2 [Homo sapiens] 44 2e-04
gi|15718680 IL2-inducible T-cell kinase [Homo sapiens] 41 0.002
gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens] 37 0.036
gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens] 37 0.036
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] 37 0.036
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] 37 0.036
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 36 0.062
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 35 0.080
gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo sap... 35 0.080
gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo sap... 35 0.080
gi|50980301 myosin phosphatase-Rho interacting protein isoform 2... 35 0.10
gi|50980307 myosin phosphatase-Rho interacting protein isoform 1... 35 0.10
gi|221219024 pleckstrin homology-like domain, family B, member 1... 35 0.14
gi|38424073 pleckstrin homology-like domain, family B, member 1 ... 35 0.14
gi|239735519 SET binding factor 1 [Homo sapiens] 35 0.14
gi|50234893 pleckstrin homology domain containing, family A (pho... 34 0.18
gi|31377720 pleckstrin homology domain containing, family A (pho... 34 0.18
gi|221219026 pleckstrin homology-like domain, family B, member 1... 34 0.23
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 33 0.31
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 33 0.52
gi|6912460 GRB2-associated binding protein 2 isoform b [Homo sap... 32 0.68
gi|7706457 A-kinase anchor protein 11 [Homo sapiens] 32 0.68
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 32 0.89
gi|197313732 pleckstrin homology-like domain, family B, member 2... 32 0.89
gi|197313730 pleckstrin homology-like domain, family B, member 2... 32 0.89
gi|197313728 pleckstrin homology-like domain, family B, member 2... 32 0.89
>gi|46391075 hypothetical protein LOC79949 [Homo sapiens]
Length = 363
Score = 729 bits (1883), Expect = 0.0
Identities = 363/363 (100%), Positives = 363/363 (100%)
Query: 1 MEPKPQKSPGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLS 60
MEPKPQKSPGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLS
Sbjct: 1 MEPKPQKSPGKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLS 60
Query: 61 YYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDR 120
YYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDR
Sbjct: 61 YYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDR 120
Query: 121 EKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNG 180
EKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNG
Sbjct: 121 EKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNG 180
Query: 181 LQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIET 240
LQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIET
Sbjct: 181 LQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIET 240
Query: 241 DGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWC 300
DGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWC
Sbjct: 241 DGPDQVSGRIECHYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWC 300
Query: 301 LSPADVEAQTTNDQKGSASLTVVQLSILINNIPDESQVEKLNVFLSPPDVINYLALTEAT 360
LSPADVEAQTTNDQKGSASLTVVQLSILINNIPDESQVEKLNVFLSPPDVINYLALTEAT
Sbjct: 301 LSPADVEAQTTNDQKGSASLTVVQLSILINNIPDESQVEKLNVFLSPPDVINYLALTEAT 360
Query: 361 GRI 363
GRI
Sbjct: 361 GRI 363
>gi|126091130 Gab3 protein isoform 1 [Homo sapiens]
Length = 587
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 20/162 (12%)
Query: 26 YFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFS---LSYYKDHHHRGSIEIDQNSSVEVG 82
+ +KSPP + +W+KR+F+L + G S + L YY++ H I + S E
Sbjct: 11 WLVKSPPERKLQRY-AWRKRWFVLRR-GRMSGNPDVLEYYRNKHSSKPIRVIDLS--ECA 66
Query: 83 ISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQ 142
+ V+K F+ + V ++TT+R ++L+ ++++ WV +S +
Sbjct: 67 VWKHVGPSFVRKEFQ--NNFVFIVKTTSRTFYLVAKTEQEMQVWVHSIS------QVCNL 118
Query: 143 NTEEELSLGNKRTLFYSSPLLGPSS-----TSEAVGSSSPRN 179
E+ + + +L Y+ L PSS T+ A SS PR+
Sbjct: 119 GHLEDGAADSMESLSYTPSSLQPSSASSLLTAHAASSSLPRD 160
>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
sapiens]
Length = 676
Score = 44.7 bits (104), Expect = 1e-04
Identities = 46/154 (29%), Positives = 69/154 (44%), Gaps = 25/154 (16%)
Query: 29 KSPPSQLFSSVTSWKKRFFILSKAGEKSFS---LSYYKDHHHRGSIEIDQNS---SVEVG 82
KSPP + +WKKR+FIL ++G S L YYK+ H + + I + V+ G
Sbjct: 15 KSPPEKKLRRY-AWKKRWFIL-RSGRMSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAG 72
Query: 83 ISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQ 142
++ +K +Q F V I+T+ R ++L+ E + WV + I Q
Sbjct: 73 LTFNKK--ELQDSF------VFDIKTSERTFYLVAETEEDMNKWVQSIC----QICGFNQ 120
Query: 143 NTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSS 176
E SL N SS GP S+ + SSS
Sbjct: 121 AEESTDSLRN-----VSSAGHGPRSSPAELSSSS 149
>gi|83716021 GRB2-associated binding protein family, member 4 [Homo
sapiens]
Length = 574
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 35/172 (20%)
Query: 29 KSPPSQLFSSVTSWKKRFFILSKAGEKSFS--LSYYKDHHHRG---SIEIDQNSSVEVGI 83
KSPP + + +W+KR+FIL + S L YYK+ + +I ++ ++V +
Sbjct: 48 KSPPEKKLR-LFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDV 106
Query: 84 SSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSF---MSSFRQDIKAT 140
+ + +QK + + I+T+ R ++L+ RE + +WV + FRQ+
Sbjct: 107 TLNFNKKEIQKGY------MFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQE---- 156
Query: 141 QQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSP 192
E LGN SS S + SS +HL ++ P
Sbjct: 157 ----ESTGFLGN------------ISSASHGLCSSPAEPSCSHQHLPQEQEP 192
>gi|18079323 Gab3 protein isoform 2 [Homo sapiens]
Length = 586
Score = 43.9 bits (102), Expect = 2e-04
Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 21/162 (12%)
Query: 26 YFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFS---LSYYKDHHHRGSIEIDQNSSVEVG 82
+ +KSPP + +W+KR+F+L + G S + L YY++ H I + S E
Sbjct: 11 WLVKSPPERKLQRY-AWRKRWFVLRR-GRMSGNPDVLEYYRNKHSSKPIRVIDLS--ECA 66
Query: 83 ISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQ 142
+ V+K F+ + V ++TT+R ++L+ ++++ WV I
Sbjct: 67 VWKHVGPSFVRKEFQ--NNFVFIVKTTSRTFYLVAKTEQEMQVWV-------HSISQVCN 117
Query: 143 NTEEELSLGNKRTLFYSSPLLGPSS-----TSEAVGSSSPRN 179
E + +L Y+ L PSS T+ A SS PR+
Sbjct: 118 LGHLEDGADSMESLSYTPSSLQPSSASSLLTAHAASSSLPRD 159
>gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]
Length = 620
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 18/114 (15%)
Query: 19 NEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHH-----RGSIEI 73
N + ++ IK + +S +++K RFF+L+KA SL+Y++D H +GSIE+
Sbjct: 3 NFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKA-----SLAYFEDRHGKKRTLKGSIEL 57
Query: 74 DQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWV 127
+ VE+ S CH + N ++ DRE + WV
Sbjct: 58 SRIKCVEIVKSDIS--------IPCHYKYPFQVVHDNYLLYVFAPDRESRQRWV 103
>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
Length = 1253
Score = 36.6 bits (83), Expect = 0.036
Identities = 27/126 (21%), Positives = 61/126 (48%), Gaps = 20/126 (15%)
Query: 16 SYENEVCKQDYFIKSPPSQLFS-SVTSWKKRFFILSKAGEKSFSLSYYKDH----HHRGS 70
S + + K + K + S ++ S+K+RFF L + G+ S++L++YKD +GS
Sbjct: 169 SQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGS 228
Query: 71 IEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDRE-KIKDWVSF 129
I +D +G+ K++ ++ ++ +L+ D E ++++W++
Sbjct: 229 IFLDSC----MGVVQNNKVRRF----------AFELKMQDKSSYLLAADSEVEMEEWITI 274
Query: 130 MSSFRQ 135
++ Q
Sbjct: 275 LNKILQ 280
>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
Length = 1254
Score = 36.6 bits (83), Expect = 0.036
Identities = 27/126 (21%), Positives = 61/126 (48%), Gaps = 20/126 (15%)
Query: 16 SYENEVCKQDYFIKSPPSQLFS-SVTSWKKRFFILSKAGEKSFSLSYYKDH----HHRGS 70
S + + K + K + S ++ S+K+RFF L + G+ S++L++YKD +GS
Sbjct: 170 SQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGS 229
Query: 71 IEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDRE-KIKDWVSF 129
I +D +G+ K++ ++ ++ +L+ D E ++++W++
Sbjct: 230 IFLDSC----MGVVQNNKVRRF----------AFELKMQDKSSYLLAADSEVEMEEWITI 275
Query: 130 MSSFRQ 135
++ Q
Sbjct: 276 LNKILQ 281
>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
Length = 2068
Score = 36.6 bits (83), Expect = 0.036
Identities = 27/126 (21%), Positives = 61/126 (48%), Gaps = 20/126 (15%)
Query: 16 SYENEVCKQDYFIKSPPSQLFS-SVTSWKKRFFILSKAGEKSFSLSYYKDH----HHRGS 70
S + + K + K + S ++ S+K+RFF L + G+ S++L++YKD +GS
Sbjct: 169 SQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGS 228
Query: 71 IEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDRE-KIKDWVSF 129
I +D +G+ K++ ++ ++ +L+ D E ++++W++
Sbjct: 229 IFLDSC----MGVVQNNKVRRF----------AFELKMQDKSSYLLAADSEVEMEEWITI 274
Query: 130 MSSFRQ 135
++ Q
Sbjct: 275 LNKILQ 280
>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
Length = 2069
Score = 36.6 bits (83), Expect = 0.036
Identities = 27/126 (21%), Positives = 61/126 (48%), Gaps = 20/126 (15%)
Query: 16 SYENEVCKQDYFIKSPPSQLFS-SVTSWKKRFFILSKAGEKSFSLSYYKDH----HHRGS 70
S + + K + K + S ++ S+K+RFF L + G+ S++L++YKD +GS
Sbjct: 170 SQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGS 229
Query: 71 IEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDRE-KIKDWVSF 129
I +D +G+ K++ ++ ++ +L+ D E ++++W++
Sbjct: 230 IFLDSC----MGVVQNNKVRRF----------AFELKMQDKSSYLLAADSEVEMEEWITI 275
Query: 130 MSSFRQ 135
++ Q
Sbjct: 276 LNKILQ 281
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 35.8 bits (81), Expect = 0.062
Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 25/168 (14%)
Query: 136 DIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSS---PRNGLQDKHLMEQSSP 192
D +++ + E ELS + R SS SE G S PR G E+ S
Sbjct: 186 DFQSSLERPELELSRHSPRK---------SSSISEEKGDSDDEKPRKG-------ERRSS 229
Query: 193 GFRQTHLQDLSEATQDVKEENHYLTP-RSVLLELD-NIIASSDSGESIETDGPDQVSGRI 250
RQ LSE +Q +EE TP R++ + D N+ + E E + D+
Sbjct: 230 RVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGD 289
Query: 251 ECHYEPMESYFFKETSHESVDSSKEEPQTL----PETQDGDLHLQEQG 294
+ + E+ KE E + + +P+ + P+T+ + + E+G
Sbjct: 290 DEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERG 337
Score = 30.4 bits (67), Expect = 2.6
Identities = 35/161 (21%), Positives = 63/161 (39%), Gaps = 10/161 (6%)
Query: 137 IKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQ 196
+++ Q++ + + N R P +G STSE+ S R+ + + SPG +
Sbjct: 607 LRSKQRDVAQARTHANPR----GRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSR 662
Query: 197 THLQDLSEATQDVKEENHYLTPRSVLLEL----DNIIASSDSGESIETDGPDQVSGRIEC 252
+E T+D TP L++ + SS S ++ P+ +
Sbjct: 663 DSSTSYTE-TKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQ 721
Query: 253 HYEPMESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQ 293
+P K + E+ + +PQT ETQ L E+
Sbjct: 722 RLQPERGSPKKCEAEEAEPPAATQPQT-SETQTSHLPESER 761
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
Length = 2365
Score = 35.4 bits (80), Expect = 0.080
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 23/154 (14%)
Query: 32 PSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQS 91
PS +S + WKK +F+L+ + SL YY+D + E+D +++ + +
Sbjct: 1797 PSLTTTSTSQWKKHWFVLTDS-----SLKYYRDSTAEEADELD--GEIDLRSCTDVTEYA 1849
Query: 92 VQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLG 151
VQ+ + I T + Y L ++W+ + R+ ++ T +LS
Sbjct: 1850 VQRNYG------FQIHTKDAVYTLSAMTSGIRRNWI---EALRKTVRPTSAPDVTKLSDS 1900
Query: 152 NKRTLFYS-SPLLGP------SSTSEAVGSSSPR 178
NK +S S GP + SE + PR
Sbjct: 1901 NKENALHSYSTQKGPLKAGEQRAGSEVISRGGPR 1934
>gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo
sapiens]
Length = 431
Score = 35.4 bits (80), Expect = 0.080
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 23/154 (14%)
Query: 32 PSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQS 91
PS +S + WKK +F+L+ + SL YY+D + E+D +++ + +
Sbjct: 84 PSLTTTSTSQWKKHWFVLTDS-----SLKYYRDSTAEEADELD--GEIDLRSCTDVTEYA 136
Query: 92 VQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLG 151
VQ+ + I T + Y L ++W+ + R+ ++ T +LS
Sbjct: 137 VQRNYG------FQIHTKDAVYTLSAMTSGIRRNWI---EALRKTVRPTSAPDVTKLSDS 187
Query: 152 NKRTLFYS-SPLLGP------SSTSEAVGSSSPR 178
NK +S S GP + SE + PR
Sbjct: 188 NKENALHSYSTQKGPLKAGEQRAGSEVISRGGPR 221
>gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo
sapiens]
Length = 652
Score = 35.4 bits (80), Expect = 0.080
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 23/154 (14%)
Query: 32 PSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQS 91
PS +S + WKK +F+L+ + SL YY+D + E+D +++ + +
Sbjct: 84 PSLTTTSTSQWKKHWFVLTDS-----SLKYYRDSTAEEADELD--GEIDLRSCTDVTEYA 136
Query: 92 VQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLG 151
VQ+ + I T + Y L ++W+ + R+ ++ T +LS
Sbjct: 137 VQRNYG------FQIHTKDAVYTLSAMTSGIRRNWI---EALRKTVRPTSAPDVTKLSDS 187
Query: 152 NKRTLFYS-SPLLGP------SSTSEAVGSSSPR 178
NK +S S GP + SE + PR
Sbjct: 188 NKENALHSYSTQKGPLKAGEQRAGSEVISRGGPR 221
>gi|50980301 myosin phosphatase-Rho interacting protein isoform 2
[Homo sapiens]
Length = 1025
Score = 35.0 bits (79), Expect = 0.10
Identities = 54/243 (22%), Positives = 98/243 (40%), Gaps = 29/243 (11%)
Query: 42 WKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPD 101
W++RFFIL + G ++L +G+I ++Q + V G + ++ QK C
Sbjct: 69 WQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDG-----EGRTGQKFSLC--- 120
Query: 102 EVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSP 161
I T +E+F+ +E + W+ + + + K Q+ KR + +P
Sbjct: 121 ----ILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQK---------KKRKVEPPTP 167
Query: 162 LLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSV 221
P AV SSS + + P + T Q+ E + + L+P
Sbjct: 168 -QEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTTKSTLWQE--EMRTKDQPDGSSLSPAQS 224
Query: 222 LLELDNIIASSDSGESIETDGPDQV--SGRIECHYE-PMESYFFKETSHESVDSSKEEPQ 278
+ ASS +E+ + S R++C + +ES +F + ++ K E Q
Sbjct: 225 PSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYF--SLEKTKQDLKAEEQ 282
Query: 279 TLP 281
LP
Sbjct: 283 QLP 285
>gi|50980307 myosin phosphatase-Rho interacting protein isoform 1
[Homo sapiens]
Length = 1038
Score = 35.0 bits (79), Expect = 0.10
Identities = 54/243 (22%), Positives = 98/243 (40%), Gaps = 29/243 (11%)
Query: 42 WKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPD 101
W++RFFIL + G ++L +G+I ++Q + V G + ++ QK C
Sbjct: 69 WQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDG-----EGRTGQKFSLC--- 120
Query: 102 EVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSP 161
I T +E+F+ +E + W+ + + + K Q+ KR + +P
Sbjct: 121 ----ILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQK---------KKRKVEPPTP 167
Query: 162 LLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQDVKEENHYLTPRSV 221
P AV SSS + + P + T Q+ E + + L+P
Sbjct: 168 -QEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTTKSTLWQE--EMRTKDQPDGSSLSPAQS 224
Query: 222 LLELDNIIASSDSGESIETDGPDQV--SGRIECHYE-PMESYFFKETSHESVDSSKEEPQ 278
+ ASS +E+ + S R++C + +ES +F + ++ K E Q
Sbjct: 225 PSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYF--SLEKTKQDLKAEEQ 282
Query: 279 TLP 281
LP
Sbjct: 283 QLP 285
>gi|221219024 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 34.7 bits (78), Expect = 0.14
Identities = 24/116 (20%), Positives = 52/116 (44%), Gaps = 16/116 (13%)
Query: 19 NEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSS 78
++VC+ Y +K + + SWKKR+F+ + +LSYY D H + +
Sbjct: 1256 SKVCR-GYLVK-----MGGKIKSWKKRWFVFDRLKR---TLSYYVDKHETKLKGVIYFQA 1306
Query: 79 VEVGISSQEKMQSVQKMFKC-------HPDEVMSIRTTNREYFLIGHDREKIKDWV 127
+E + + ++ F+ +P ++T +R Y+++ E ++ W+
Sbjct: 1307 IEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWM 1362
>gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 34.7 bits (78), Expect = 0.14
Identities = 24/116 (20%), Positives = 52/116 (44%), Gaps = 16/116 (13%)
Query: 19 NEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSS 78
++VC+ Y +K + + SWKKR+F+ + +LSYY D H + +
Sbjct: 1256 SKVCR-GYLVK-----MGGKIKSWKKRWFVFDRLKR---TLSYYVDKHETKLKGVIYFQA 1306
Query: 79 VEVGISSQEKMQSVQKMFKC-------HPDEVMSIRTTNREYFLIGHDREKIKDWV 127
+E + + ++ F+ +P ++T +R Y+++ E ++ W+
Sbjct: 1307 IEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWM 1362
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 34.7 bits (78), Expect = 0.14
Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 19/122 (15%)
Query: 16 SYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQ 75
SYE + K+ F+K WK R+F+L K + + D +G I++ +
Sbjct: 1789 SYEGTLYKKGAFMKP-----------WKARWFVLDKTKHQLRYYDHRVDTECKGVIDLAE 1837
Query: 76 NSSVEVGISSQEKMQSV-QKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFR 134
+V G + ++V +K F ++TT R Y D + WV + S
Sbjct: 1838 VEAVAPGTPTMGAPKTVDEKAF-------FDVKTTRRVYNFCAQDVPSAQQWVDRIQSCL 1890
Query: 135 QD 136
D
Sbjct: 1891 SD 1892
>gi|50234893 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1 [Homo
sapiens]
Length = 404
Score = 34.3 bits (77), Expect = 0.18
Identities = 33/172 (19%), Positives = 70/172 (40%), Gaps = 19/172 (11%)
Query: 18 ENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNS 77
++ V K Y +K + + +WK+R+F L + ++ Y+K E+++
Sbjct: 189 DSAVIKAGYCVKQG-----AVMKNWKRRYFQLDEN-----TIGYFKS-------ELEKEP 231
Query: 78 SVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDI 137
+ + K+Q ++ D + I TT+R +++ E++ W+ +S
Sbjct: 232 LRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQ 291
Query: 138 KATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQ 189
+ ++ E G + P ++TS + S S N L ME+
Sbjct: 292 RGPGRSASSEHPPGPSESKHAFRPTNAATATSHSTASRS--NSLVSTFTMEK 341
>gi|31377720 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1 [Homo
sapiens]
Length = 404
Score = 34.3 bits (77), Expect = 0.18
Identities = 33/172 (19%), Positives = 70/172 (40%), Gaps = 19/172 (11%)
Query: 18 ENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNS 77
++ V K Y +K + + +WK+R+F L + ++ Y+K E+++
Sbjct: 189 DSAVIKAGYCVKQG-----AVMKNWKRRYFQLDEN-----TIGYFKS-------ELEKEP 231
Query: 78 SVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDI 137
+ + K+Q ++ D + I TT+R +++ E++ W+ +S
Sbjct: 232 LRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQ 291
Query: 138 KATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQ 189
+ ++ E G + P ++TS + S S N L ME+
Sbjct: 292 RGPGRSASSEHPPGPSESKHAFRPTNAATATSHSTASRS--NSLVSTFTMEK 341
>gi|221219026 pleckstrin homology-like domain, family B, member 1
isoform b [Homo sapiens]
Length = 1319
Score = 33.9 bits (76), Expect = 0.23
Identities = 25/118 (21%), Positives = 51/118 (43%), Gaps = 31/118 (26%)
Query: 19 NEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSS 78
++VC+ Y +K + + SWKKR+F+ + +LSYY D H
Sbjct: 1209 SKVCR-GYLVK-----MGGKIKSWKKRWFVFDRLKR---TLSYYVDKH------------ 1247
Query: 79 VEVGISSQEKMQSVQKMFKCH---------PDEVMSIRTTNREYFLIGHDREKIKDWV 127
E + Q++++++ H P ++T +R Y+++ E ++ W+
Sbjct: 1248 -ETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWM 1304
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 33.5 bits (75), Expect = 0.31
Identities = 30/88 (34%), Positives = 44/88 (50%), Gaps = 11/88 (12%)
Query: 155 TLFYSSPLLG-PSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQDVKEEN 213
+L SSP+ PSSTS ++ SSP + LQ + SS T L SE + +E
Sbjct: 824 SLSQSSPVSSFPSSTSSSLSKSSPESPLQSPVISFSSS-----TSLSPFSEESSSPVDE- 877
Query: 214 HYLTPRSVLLELDNIIASSDSGESIETD 241
Y + LLE D++ +DS IE++
Sbjct: 878 -YTSSSDTLLESDSL---TDSESLIESE 901
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 32.7 bits (73), Expect = 0.52
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 9/99 (9%)
Query: 149 SLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQD 208
SL K T FY+SP ++ S A +SS G+ ++ S PG TH ++T
Sbjct: 2518 SLSEKSTTFYTSPRSPDATLSPATTTSS---GVSEESSTSHSQPG--STHTTAFPDSTTT 2572
Query: 209 VKEENHYLTPRSVLLELDNIIASSDSGESIETDGPDQVS 247
H T S D + + S T GP Q S
Sbjct: 2573 PGLSRHSTTSHSSPGSTDTTLLPA----STTTSGPSQES 2607
Score = 32.0 bits (71), Expect = 0.89
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 149 SLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQD 208
SL K T FY+SP ++ S A +SS G+ ++ S PG T S T D
Sbjct: 1435 SLSEKSTTFYTSPRSPDATLSPATTTSS---GVSEESSTSHSQPGSTHTTAFPDSTTTSD 1491
Query: 209 VKEE 212
+ +E
Sbjct: 1492 LSQE 1495
Score = 29.3 bits (64), Expect = 5.8
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 149 SLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQD 208
SL K T FY+SP ++ S A +SS G+ ++ S PG T S T
Sbjct: 2992 SLSEKSTTFYTSPRSPDATLSPATTTSS---GVSEESSTSHSQPGSTHTTAFPDSTTTSG 3048
Query: 209 VKEE 212
+ +E
Sbjct: 3049 LSQE 3052
Score = 29.3 bits (64), Expect = 5.8
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 149 SLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQD 208
SL K T FY+SP ++ S A +SS G+ ++ S PG T S T
Sbjct: 4075 SLSEKSTTFYTSPRSPDATLSPATTTSS---GVSEESSTSHSQPGSTHTTAFPDSTTTSG 4131
Query: 209 VKEE 212
+ +E
Sbjct: 4132 LSQE 4135
>gi|6912460 GRB2-associated binding protein 2 isoform b [Homo
sapiens]
Length = 638
Score = 32.3 bits (72), Expect = 0.68
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 20/121 (16%)
Query: 59 LSYYKDHHHRGSIEIDQNS---SVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFL 115
L YYK+ H + + I + V+ G++ +K +Q F V I+T+ R ++L
Sbjct: 8 LEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKK--ELQDSF------VFDIKTSERTFYL 59
Query: 116 IGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSS 175
+ E + WV + I Q E SL N SS GP S+ + SS
Sbjct: 60 VAETEEDMNKWVQSIC----QICGFNQAEESTDSLRN-----VSSAGHGPRSSPAELSSS 110
Query: 176 S 176
S
Sbjct: 111 S 111
>gi|7706457 A-kinase anchor protein 11 [Homo sapiens]
Length = 1901
Score = 32.3 bits (72), Expect = 0.68
Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 2/122 (1%)
Query: 202 LSEATQDVKEENHYLTPRSVLLELDNIIASSDSGESIETDGPDQVSGRIECHYEPMESYF 261
LSE Q+ E+ ++ ++ L + SS+SGE E D + SG+ E + ++
Sbjct: 1149 LSENEQNTIEKEEFML--KLMRSLSEEVESSESGELPEVDVKSEHSGKKVQFAEALATHI 1206
Query: 262 FKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWCLSPADVEAQTTNDQKGSASLT 321
+ + + P+ ++ L++Q Q S L+P+D +T + G +
Sbjct: 1207 LSLATEMAASHLDNKIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLKTLCNFAGDLAAE 1266
Query: 322 VV 323
V+
Sbjct: 1267 VI 1268
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 32.0 bits (71), Expect = 0.89
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 149 SLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQDLSEATQD 208
SL K T FY+SP ++ S A +SS G+ ++ S PG T S T D
Sbjct: 922 SLSEKSTTFYTSPRSPDATLSPATTTSS---GVSEESSTSHSQPGSTHTTAFPDSTTTSD 978
Query: 209 VKEE 212
+ +E
Sbjct: 979 LSQE 982
>gi|197313732 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 32.0 bits (71), Expect = 0.89
Identities = 21/98 (21%), Positives = 45/98 (45%), Gaps = 25/98 (25%)
Query: 39 VTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKC 98
+ +WKKR+F+ + +++FS YY D H E + Q++++++
Sbjct: 1157 IKTWKKRWFVFDR-NKRTFS--YYADKH-------------ETKLKGVIYFQAIEEVYYD 1200
Query: 99 H---------PDEVMSIRTTNREYFLIGHDREKIKDWV 127
H P S++T +R Y+++ E ++ W+
Sbjct: 1201 HLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWM 1238
>gi|197313730 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 32.0 bits (71), Expect = 0.89
Identities = 21/98 (21%), Positives = 45/98 (45%), Gaps = 25/98 (25%)
Query: 39 VTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKC 98
+ +WKKR+F+ + +++FS YY D H E + Q++++++
Sbjct: 1157 IKTWKKRWFVFDR-NKRTFS--YYADKH-------------ETKLKGVIYFQAIEEVYYD 1200
Query: 99 H---------PDEVMSIRTTNREYFLIGHDREKIKDWV 127
H P S++T +R Y+++ E ++ W+
Sbjct: 1201 HLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWM 1238
>gi|197313728 pleckstrin homology-like domain, family B, member 2
isoform b [Homo sapiens]
Length = 1237
Score = 32.0 bits (71), Expect = 0.89
Identities = 21/98 (21%), Positives = 45/98 (45%), Gaps = 25/98 (25%)
Query: 39 VTSWKKRFFILSKAGEKSFSLSYYKDHHHRGSIEIDQNSSVEVGISSQEKMQSVQKMFKC 98
+ +WKKR+F+ + +++FS YY D H E + Q++++++
Sbjct: 1141 IKTWKKRWFVFDR-NKRTFS--YYADKH-------------ETKLKGVIYFQAIEEVYYD 1184
Query: 99 H---------PDEVMSIRTTNREYFLIGHDREKIKDWV 127
H P S++T +R Y+++ E ++ W+
Sbjct: 1185 HLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWM 1222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,694,139
Number of Sequences: 37866
Number of extensions: 673422
Number of successful extensions: 1868
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 1816
Number of HSP's gapped (non-prelim): 126
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.