Search of human proteins with 46255068

Search of human proteins with 46255068

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
         (365 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]             739   0.0  
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]             738   0.0  
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]            738   0.0  
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]            738   0.0  
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]             738   0.0  
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]             738   0.0  
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]             738   0.0  
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]             667   0.0  
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]            664   0.0  
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       328   4e-90
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      289   3e-78
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      289   3e-78
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]            254   7e-68
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]             254   7e-68
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]            252   4e-67
gi|110227631 synaptotagmin-like 3 [Homo sapiens]                      195   6e-50
gi|238550198 synaptotagmin III [Homo sapiens]                         112   7e-25
gi|238550196 synaptotagmin III [Homo sapiens]                         112   7e-25
gi|14150054 synaptotagmin III [Homo sapiens]                          112   7e-25
gi|45504376 synaptotagmin VI [Homo sapiens]                           111   9e-25
gi|211059429 synaptotagmin II [Homo sapiens]                          110   2e-24
gi|31543670 synaptotagmin II [Homo sapiens]                           110   2e-24
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            107   1e-23
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             107   1e-23
gi|39752671 synaptotagmin X [Homo sapiens]                            107   2e-23
gi|6005997 double C2-like domains, beta [Homo sapiens]                107   2e-23
gi|209447073 synaptotagmin I [Homo sapiens]                           102   7e-22
gi|5032139 synaptotagmin I [Homo sapiens]                             102   7e-22
gi|209447070 synaptotagmin I [Homo sapiens]                           102   7e-22
gi|28376627 synaptotagmin IX [Homo sapiens]                           101   9e-22

>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
          Length = 365

 Score =  739 bits (1909), Expect = 0.0
 Identities = 365/365 (100%), Positives = 365/365 (100%)

Query: 1   MSDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 60
           MSDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK
Sbjct: 1   MSDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 60

Query: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
           GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK
Sbjct: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120

Query: 121 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 180
           KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ
Sbjct: 121 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 180

Query: 181 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 240
           LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG
Sbjct: 181 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 240

Query: 241 SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 300
           SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH
Sbjct: 241 SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 300

Query: 301 YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 360
           YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI
Sbjct: 301 YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 360

Query: 361 AKISK 365
           AKISK
Sbjct: 361 AKISK 365


>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
          Length = 376

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 2   SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61
           SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 13  SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 72

Query: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
           NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 73  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 132

Query: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
           TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 133 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 192

Query: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241
           RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 193 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 252

Query: 242 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301
           HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 253 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 312

Query: 302 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361
           KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 313 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 372

Query: 362 KISK 365
           KISK
Sbjct: 373 KISK 376


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 2   SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61
           SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 572 SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 631

Query: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
           NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 632 NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 691

Query: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
           TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 692 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 751

Query: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241
           RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 752 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 811

Query: 242 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301
           HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 812 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 871

Query: 302 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361
           KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 872 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 931

Query: 362 KISK 365
           KISK
Sbjct: 932 KISK 935


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 2   SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61
           SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 571 SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 630

Query: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
           NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 631 NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 690

Query: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
           TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 691 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 750

Query: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241
           RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 751 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 810

Query: 242 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301
           HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 811 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 870

Query: 302 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361
           KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 871 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 930

Query: 362 KISK 365
           KISK
Sbjct: 931 KISK 934


>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
          Length = 376

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 2   SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61
           SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 13  SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 72

Query: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
           NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 73  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 132

Query: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
           TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 133 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 192

Query: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241
           RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 193 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 252

Query: 242 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301
           HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 253 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 312

Query: 302 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361
           KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 313 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 372

Query: 362 KISK 365
           KISK
Sbjct: 373 KISK 376


>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
          Length = 1256

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 2    SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61
            SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 893  SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 952

Query: 62   NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
            NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 953  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 1012

Query: 122  TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
            TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 1013 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 1072

Query: 182  RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241
            RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 1073 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 1132

Query: 242  HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301
            HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 1133 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 1192

Query: 302  KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361
            KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 1193 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 1252

Query: 362  KISK 365
            KISK
Sbjct: 1253 KISK 1256


>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
          Length = 1272

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 2    SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61
            SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 909  SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 968

Query: 62   NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
            NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 969  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 1028

Query: 122  TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
            TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 1029 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 1088

Query: 182  RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241
            RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 1089 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 1148

Query: 242  HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301
            HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 1149 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 1208

Query: 302  KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361
            KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 1209 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 1268

Query: 362  KISK 365
            KISK
Sbjct: 1269 KISK 1272


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score =  667 bits (1721), Expect = 0.0
 Identities = 328/342 (95%), Positives = 329/342 (96%)

Query: 24  PSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQC 83
           P  L  +S S        VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQC
Sbjct: 569 PDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQC 628

Query: 84  KDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQ 143
           KDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQ
Sbjct: 629 KDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQ 688

Query: 144 KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEM 203
           KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEM
Sbjct: 689 KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEM 748

Query: 204 KLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKT 263
           KLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKT
Sbjct: 749 KLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKT 808

Query: 264 RAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGT 323
           RAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGT
Sbjct: 809 RAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGT 868

Query: 324 EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 365
           EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Sbjct: 869 EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 910


>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
          Length = 336

 Score =  664 bits (1712), Expect = 0.0
 Identities = 324/324 (100%), Positives = 324/324 (100%)

Query: 42  VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 101
           VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK
Sbjct: 13  VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 72

Query: 102 AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 161
           AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL
Sbjct: 73  AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 132

Query: 162 GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPT 221
           GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPT
Sbjct: 133 GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPT 192

Query: 222 TGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYD 281
           TGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYD
Sbjct: 193 TGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYD 252

Query: 282 GFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKM 341
           GFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKM
Sbjct: 253 GFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKM 312

Query: 342 VNSPNTWIEATLPLRMLLIAKISK 365
           VNSPNTWIEATLPLRMLLIAKISK
Sbjct: 313 VNSPNTWIEATLPLRMLLIAKISK 336


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  328 bits (842), Expect = 4e-90
 Identities = 167/335 (49%), Positives = 229/335 (68%), Gaps = 11/335 (3%)

Query: 24  PSSLTNLSSSSGMTSLSS--VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVA 81
           PS    LSSSS ++SL+S  +SGS MS+ SGD   ++V+G++ FA+ Y     EL V V 
Sbjct: 218 PSLDRMLSSSSSVSSLNSSTLSGSQMSL-SGDAEAVQVRGSVHFALHYEPGAAELRVHVI 276

Query: 82  QCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILK 141
           QC+ LAAA  +++RSDPYVK+YLLPDK    K+KT V K+ LNPV+NE LRY + +  L+
Sbjct: 277 QCQGLAAA--RRRRSDPYVKSYLLPDK--QSKRKTAVKKRNLNPVFNETLRYSVPQAELQ 332

Query: 142 TQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRG 201
            + L+LS+WHR++  RN FLGEVE+ L+TWDW ++      W PL+ +  P   +  +RG
Sbjct: 333 GRVLSLSVWHRESLGRNIFLGEVEVPLDTWDWGSEPT----WLPLQPRVPPSPDDLPSRG 388

Query: 202 EMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQ 261
            + L+L+YVP    G  LP +GE+H WVKE  DL  LR   L+++V+C +LPD S+ SRQ
Sbjct: 389 LLALSLKYVPAGSEGAGLPPSGELHFWVKEARDLLPLRAGSLDTYVQCFVLPDDSQASRQ 448

Query: 262 KTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSY 321
           +TR V ++ +P+FNHTMVYDGF P DL +AC EL++WDH  L N+ LGG R+  GTG SY
Sbjct: 449 RTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALANRQLGGTRLSLGTGSSY 508

Query: 322 GTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 356
           G +V WMDST EE  LW+ ++  P  W++  LPLR
Sbjct: 509 GLQVPWMDSTPEEKQLWQALLEQPCEWVDGLLPLR 543


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  289 bits (739), Expect = 3e-78
 Identities = 155/364 (42%), Positives = 227/364 (62%), Gaps = 16/364 (4%)

Query: 4   DRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKG 61
           D E +   E    L +  +   + +++ S S M+++    GS+MS+YS  GDFGN+ V G
Sbjct: 303 DMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTI----GSMMSIYSEAGDFGNIFVTG 358

Query: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
            I F+++Y +  + L V V +C  LA AD  K+RS+PYVK YLLPDK + GK+KT + + 
Sbjct: 359 RIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRD 418

Query: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
           T+NP+Y+E LRY+I + +L  + L  S+WH   F RN+FLGE E+ +++W  D K +  L
Sbjct: 419 TINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCL 478

Query: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLD 234
             +      +P  L + ++GE+ ++L+Y+P    PV G +  +     GE+ +W+KE  +
Sbjct: 479 PLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 235 LPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 293
           L   + G   +SFVK  +LP  ++ S++KT  + KT NP +NHT VY+G R EDL   C+
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 294 ELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEAT 352
           ELTVWD   L +N FLGG+R+G GTG S G  VDWMDST EEV+LW+KM   P +W E T
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657

Query: 353 LPLR 356
           L LR
Sbjct: 658 LQLR 661


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  289 bits (739), Expect = 3e-78
 Identities = 155/364 (42%), Positives = 227/364 (62%), Gaps = 16/364 (4%)

Query: 4   DRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKG 61
           D E +   E    L +  +   + +++ S S M+++    GS+MS+YS  GDFGN+ V G
Sbjct: 303 DMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTI----GSMMSIYSEAGDFGNIFVTG 358

Query: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
            I F+++Y +  + L V V +C  LA AD  K+RS+PYVK YLLPDK + GK+KT + + 
Sbjct: 359 RIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRD 418

Query: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
           T+NP+Y+E LRY+I + +L  + L  S+WH   F RN+FLGE E+ +++W  D K +  L
Sbjct: 419 TINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCL 478

Query: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLD 234
             +      +P  L + ++GE+ ++L+Y+P    PV G +  +     GE+ +W+KE  +
Sbjct: 479 PLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 235 LPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 293
           L   + G   +SFVK  +LP  ++ S++KT  + KT NP +NHT VY+G R EDL   C+
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 294 ELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEAT 352
           ELTVWD   L +N FLGG+R+G GTG S G  VDWMDST EEV+LW+KM   P +W E T
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657

Query: 353 LPLR 356
           L LR
Sbjct: 658 LQLR 661


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  254 bits (650), Expect = 7e-68
 Identities = 147/379 (38%), Positives = 222/379 (58%), Gaps = 35/379 (9%)

Query: 4   DRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKG 61
           D+++   +E S       +  ++   L+S    TSL+S+    MSVYS  GD+GN++V G
Sbjct: 353 DKDSLEETEESIDALVSSQLSTNTHRLASGLSTTSLNSM----MSVYSETGDYGNVKVSG 408

Query: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
            I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+KT +   
Sbjct: 409 EILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTG 468

Query: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
           T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++W+++N  ++  
Sbjct: 469 T-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDE-- 525

Query: 182 RWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK-----------L 219
            W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K           +
Sbjct: 526 -WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPV 583

Query: 220 PTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTM 278
            + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ NP +NHT 
Sbjct: 584 ISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTF 643

Query: 279 VYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVAL 337
           ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS  EE  L
Sbjct: 644 MFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRL 703

Query: 338 WEKMVNSPNTWIEATLPLR 356
           W+KM N+P T  E  L LR
Sbjct: 704 WQKMANNPGTPFEGVLMLR 722


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  254 bits (650), Expect = 7e-68
 Identities = 147/379 (38%), Positives = 222/379 (58%), Gaps = 35/379 (9%)

Query: 4   DRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKG 61
           D+++   +E S       +  ++   L+S    TSL+S+    MSVYS  GD+GN++V G
Sbjct: 353 DKDSLEETEESIDALVSSQLSTNTHRLASGLSTTSLNSM----MSVYSETGDYGNVKVSG 408

Query: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
            I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPDK +  K+KT +   
Sbjct: 409 EILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTG 468

Query: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
           T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+  ++W+++N  ++  
Sbjct: 469 T-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDE-- 525

Query: 182 RWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPGKK-----------L 219
            W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G K           +
Sbjct: 526 -WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPV 583

Query: 220 PTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTM 278
            + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT  + K+ NP +NHT 
Sbjct: 584 ISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTF 643

Query: 279 VYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVAL 337
           ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G  VDWMDS  EE  L
Sbjct: 644 MFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRL 703

Query: 338 WEKMVNSPNTWIEATLPLR 356
           W+KM N+P T  E  L LR
Sbjct: 704 WQKMANNPGTPFEGVLMLR 722


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score =  252 bits (643), Expect = 4e-67
 Identities = 143/351 (40%), Positives = 211/351 (60%), Gaps = 35/351 (9%)

Query: 32  SSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 89
           + S  TSL+S+    MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  
Sbjct: 403 ADSDTTSLNSM----MSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIG 458

Query: 90  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 149
           D KKQR+D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+
Sbjct: 459 DEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSV 517

Query: 150 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLAL 207
           WH D F RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L
Sbjct: 518 WHYDRFGRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVL 573

Query: 208 QYV---------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSF 246
           +Y+         PE + G K           + + G + +++KE  +L  ++ G   +SF
Sbjct: 574 RYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSF 633

Query: 247 VKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TN 305
           VK  +LPD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N
Sbjct: 634 VKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN 693

Query: 306 QFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 356
            FLGG+R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 694 IFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744


>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
          Length = 542

 Score =  195 bits (495), Expect = 6e-50
 Identities = 124/348 (35%), Positives = 188/348 (54%), Gaps = 27/348 (7%)

Query: 29  NLSSSSGMTSLSSVS---GSVMSVYS-----GDFGNLEVKGNIQFAIEYVESLKELHVFV 80
           NL SS   +++ S     GS++S+ S     G+F N  V G I+FAI Y      L + +
Sbjct: 200 NLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICI 259

Query: 81  AQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQIL 140
             CK+LA  + KK++ +PYVK YLLPD+   GK+KT V + T++P + E L+Y++    L
Sbjct: 260 KACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQL 319

Query: 141 KTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-EN 199
            T++L +S+WH  T  R  FLGEV + L TWD+++   +  RW+PL+ K         ++
Sbjct: 320 VTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQS 379

Query: 200 RGEM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-C 249
            GE+    KL L   P    E   G   P+  G++ + V    +LP+     LNSFVK C
Sbjct: 380 NGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGC 439

Query: 250 TILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQF 307
             LPD  +K R K+  + K   P + H+ V+ G  P  L ++ +ELTVWD   + + ++ 
Sbjct: 440 LTLPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRL 498

Query: 308 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 355
           LGG R+G     S G      D+ S     W+K+++SPN W + TL L
Sbjct: 499 LGGTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 7e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 51  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 110
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 111 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 168
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 169 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 228
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 229 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 287
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 288 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 342
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 7e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 51  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 110
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 111 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 168
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 169 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 228
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 229 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 287
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 288 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 342
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 7e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 51  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 110
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 111 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 168
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 169 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 228
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 229 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 287
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 288 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 342
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  111 bits (278), Expect = 9e-25
 Identities = 84/295 (28%), Positives = 152/295 (51%), Gaps = 25/295 (8%)

Query: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
           G I F++ Y    + L V + +  DL A D     SDPYVK YLLPD+    K +T V +
Sbjct: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGS-SDPYVKIYLLPDR--KCKLQTRVHR 202

Query: 121 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 180
           KTLNP ++E   + +  + L  +KL+LS++  D F R+  +GEV LD   ++  +   + 
Sbjct: 203 KTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRET 261

Query: 181 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 239
             W  ++  T+    E+ + GE+  +L Y         LPT G + + V +C +L  +  
Sbjct: 262 SIWKDIQYATS----ESVDLGEIMFSLCY---------LPTAGRLTLTVIKCRNLKAMDI 308

Query: 240 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 299
             + + +VK ++L D  R  ++KT     T NP++N  +++D   PE++ +  + ++V D
Sbjct: 309 TGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSLLISVMD 367

Query: 300 HYKL-TNQFLGGLRIGF---GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIE 350
           + ++  N+ +G  R+G    G G+ +  E+  +    + +A W  +V    ++ E
Sbjct: 368 YDRVGHNEIIGVCRVGITAEGLGRDHWNEM--LAYPRKPIAHWHSLVEVKKSFKE 420


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 2e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
           G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 121 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 180
           KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 181 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 239
             W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257 --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 240 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 299
           G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303 GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 300 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 353
           + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362 YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 58  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 117
           E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 118 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 170
           V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 171 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 200
           W     N +    +W+ LK +    AL  +N+
Sbjct: 388 WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 2e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
           G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 121 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 180
           KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 181 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 239
             W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257 --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 240 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 299
           G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303 GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 300 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 353
           + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362 YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 58  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 117
           E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 118 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 170
           V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 171 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 200
           W     N +    +W+ LK +    AL  +N+
Sbjct: 388 WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)

Query: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
           G ++F++ Y +    L   + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 394 GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 452

Query: 121 KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 179
            T NP++NE L Y  I  + ++ + L +S+   D F  N F+GE    L+    + ++N 
Sbjct: 453 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 512

Query: 180 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 221
            +   R  P+KR         +AL          + E RG++ ++L Y  +         
Sbjct: 513 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 563

Query: 222 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 280
            G + + +  C+ L  +    + + FVK  + PD  +K++ KT+   KT NP FN    Y
Sbjct: 564 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 623

Query: 281 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 338
           D  +  DL +  ++++VWD+    +N ++GG ++G    G+      + + +  +++  W
Sbjct: 624 D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 682

Query: 339 EKMVN 343
            ++ N
Sbjct: 683 HQLQN 687



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 55  GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 114
           G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 546 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 604

Query: 115 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 167
           KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 605 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 664

Query: 168 LETW--DWDNKQNKQLRWYPLKRK 189
           L+ W     NK  K  RW+ L+ +
Sbjct: 665 LKHWYECLKNKDKKIERWHQLQNE 688


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)

Query: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
           G ++F++ Y +    L   + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 390 GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 448

Query: 121 KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 179
            T NP++NE L Y  I  + ++ + L +S+   D F  N F+GE    L+    + ++N 
Sbjct: 449 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 508

Query: 180 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 221
            +   R  P+KR         +AL          + E RG++ ++L Y  +         
Sbjct: 509 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 559

Query: 222 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 280
            G + + +  C+ L  +    + + FVK  + PD  +K++ KT+   KT NP FN    Y
Sbjct: 560 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 619

Query: 281 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 338
           D  +  DL +  ++++VWD+    +N ++GG ++G    G+      + + +  +++  W
Sbjct: 620 D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 678

Query: 339 EKMVN 343
            ++ N
Sbjct: 679 HQLQN 683



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 55  GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 114
           G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600

Query: 115 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 167
           KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660

Query: 168 LETW--DWDNKQNKQLRWYPLKRK 189
           L+ W     NK  K  RW+ L+ +
Sbjct: 661 LKHWYECLKNKDKKIERWHQLQNE 684


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  107 bits (266), Expect = 2e-23
 Identities = 79/276 (28%), Positives = 144/276 (52%), Gaps = 25/276 (9%)

Query: 56  NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 115
           ++++ G + F ++Y    + L V + +  DL A D     SDPYVK YLLPD+ K  K +
Sbjct: 228 DVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGT-SDPYVKMYLLPDRKK--KFQ 284

Query: 116 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDN 175
           T V +KTLNP+++E  ++ +    L  +KL+ S++  D F R+  +GEV LD   ++  +
Sbjct: 285 TRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILD-NLFEVSD 343

Query: 176 KQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 235
              +   W  +   T     E+ + GE+  +L Y         LPT G + + V +C +L
Sbjct: 344 LSREATVWKDIHCATT----ESIDLGEIMFSLCY---------LPTAGRMTLTVIKCRNL 390

Query: 236 PL--LRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 293
               + GS  + +VK +++ +  R  ++KT     T NP++N  +++D   PE++ +  +
Sbjct: 391 KAMDITGSS-DPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFD-IPPENVDQVSL 448

Query: 294 ELTVWDHYKL-TNQFLGGLRIGF---GTGKSYGTEV 325
            + V D+ ++  N+ +G  R G    G G+ +  E+
Sbjct: 449 SIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEM 484


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  107 bits (266), Expect = 2e-23
 Identities = 79/291 (27%), Positives = 133/291 (45%), Gaps = 23/291 (7%)

Query: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
           G + F++ Y +    LH  + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 128 GTLDFSLLYDQENNALHCTITKAKGLKPMD-HNGLADPYVKLHLLPGASKANKLRTKTLR 186

Query: 121 KTLNPVYNEILR-YKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 179
            TLNP +NE L  Y I  + +  + L +S+   D F+ N F+GE  + L+      K N 
Sbjct: 187 NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKL----KPNH 242

Query: 180 QLRWYPLKRKTAPV----ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 235
              +     K  PV        E RG + ++L+Y  +            + + +  C  L
Sbjct: 243 TKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQ---------KQGLLVGIVRCAHL 293

Query: 236 PLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVE 294
             +    + + +VK  + PD  +KS+ KT    KT NP FN    Y+  +  DL +  +E
Sbjct: 294 AAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLE 352

Query: 295 LTVWDH-YKLTNQFLGGLRIGF-GTGKSYGTEVDWMDSTSEEVALWEKMVN 343
           +TVWD+    +N F+GG+ +G    G+      D + +  + +  W  + +
Sbjct: 353 VTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTS 403



 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 10/140 (7%)

Query: 56  NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 115
           +LE +G I  +++Y    + L V + +C  LAA D     SDPYVK YL PD  K  K K
Sbjct: 263 SLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGY-SDPYVKTYLRPDVDKKSKHK 321

Query: 116 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD-------L 168
           T V KKTLNP +NE   Y+I+   L  + L +++W  D  K N F+G V L        L
Sbjct: 322 TAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERL 381

Query: 169 ETW--DWDNKQNKQLRWYPL 186
           + W     NK  +  RW+ L
Sbjct: 382 KHWFDCLKNKDKRIERWHTL 401


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 7e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 58  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 117
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 118 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 177
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 178 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 237
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 238 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 296
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 297 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 345
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 7e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 58  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 117
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 118 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 177
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 178 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 237
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 238 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 296
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 297 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 345
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 7e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 58  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 117
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 118 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 177
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 178 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 237
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 238 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 296
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 297 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 345
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  101 bits (252), Expect = 9e-22
 Identities = 86/347 (24%), Positives = 169/347 (48%), Gaps = 31/347 (8%)

Query: 7   TDTASESSYQLSRHKKSPS-SLTNLSSSSGMTSLSSVSGSVMSVYS-----GDFGNLEVK 60
           T +A  +S +   +  +P  ++  L     +T +  +   +    S     G   N +  
Sbjct: 162 TSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKAC 221

Query: 61  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 120
           G + F ++Y   L++L V + +  +L A D     SDPYVK YLLPD+    K +T V +
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGT-SDPYVKIYLLPDRKT--KHQTKVHR 278

Query: 121 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 180
           KTLNPV++E+  + +    L+ +KL+ S++  D F R+  +G+V +D    D  +   + 
Sbjct: 279 KTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD-HFLDLADFPREC 337

Query: 181 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 240
           + W  ++     V  +  + GE+  +L Y         LPT G + I + +  +L  +  
Sbjct: 338 ILWKDIEY----VTNDNVDLGELMFSLCY---------LPTAGRLTITIIKARNLKAMDI 384

Query: 241 SHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 299
           +  +  +VK +++ D  R  ++KT     T NP++N  +V+D   PE++ +  + + V D
Sbjct: 385 TGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFD-VPPENIDQIHLSIAVMD 443

Query: 300 HYKL-TNQFLGGLRIGFGT---GKSYGTEVDWMDSTSEEVALWEKMV 342
           + ++  N+ +G  ++G      G+ + +E+  +    + +A W  +V
Sbjct: 444 YDRVGHNEIIGVCQVGNEAERLGRDHWSEM--LSYPRKPIAHWHSLV 488


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,521,610
Number of Sequences: 37866
Number of extensions: 603539
Number of successful extensions: 2315
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 1886
Number of HSP's gapped (non-prelim): 313
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.