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Search of human proteins with 4557421
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2
isoform 2 [Homo sapiens]
(472 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isof... 958 0.0
gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2 iso... 945 0.0
gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8 is... 382 e-106
gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [H... 369 e-102
gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8 is... 363 e-100
gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1 is... 335 5e-92
gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1 iso... 335 5e-92
gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4 is... 130 2e-30
gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isof... 130 3e-30
gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Hom... 124 2e-28
gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Hom... 111 1e-24
gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 is... 94 3e-19
gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 is... 94 3e-19
gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo ... 30 6.2
gi|239743315 PREDICTED: hypothetical protein XP_002342820 [Homo ... 30 6.2
gi|239508997 PREDICTED: hypothetical protein [Homo sapiens] 30 6.2
gi|5032105 small optic lobes [Homo sapiens] 30 6.2
>gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isoform
2 [Homo sapiens]
Length = 472
Score = 958 bits (2476), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA 60
MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
Sbjct: 1 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA 60
Query: 61 DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG 120
DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
Sbjct: 61 DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG 120
Query: 121 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF 180
ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
Sbjct: 121 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF 180
Query: 181 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF 240
IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
Sbjct: 181 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF 240
Query: 241 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS 300
LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS
Sbjct: 241 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS 300
Query: 301 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG 360
LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
Sbjct: 301 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG 360
Query: 361 LPVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLN 420
LPVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLN
Sbjct: 361 LPVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLN 420
Query: 421 LTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI 472
LTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
Sbjct: 421 LTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI 472
>gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2
isoform 1 [Homo sapiens]
Length = 495
Score = 945 bits (2442), Expect = 0.0
Identities = 472/495 (95%), Positives = 472/495 (95%), Gaps = 23/495 (4%)
Query: 1 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA 60
MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
Sbjct: 1 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA 60
Query: 61 DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG 120
DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
Sbjct: 61 DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG 120
Query: 121 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF 180
ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
Sbjct: 121 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF 180
Query: 181 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF 240
IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
Sbjct: 181 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF 240
Query: 241 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS 300
LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS
Sbjct: 241 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS 300
Query: 301 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG 360
LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
Sbjct: 301 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG 360
Query: 361 LPVATLQQLEAAAVNVCNQTWA-----------------------QQLLSRGYGFDERAF 397
LPVATLQQLEAAAVNVCNQTWA QQLLSRGYGFDERAF
Sbjct: 361 LPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAF 420
Query: 398 GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV 457
GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV
Sbjct: 421 GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV 480
Query: 458 LLLRQVHSAKLPSTI 472
LLLRQVHSAKLPSTI
Sbjct: 481 LLLRQVHSAKLPSTI 495
>gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8
isoform 1 [Homo sapiens]
Length = 495
Score = 382 bits (982), Expect = e-106
Identities = 204/483 (42%), Positives = 282/483 (58%), Gaps = 37/483 (7%)
Query: 13 LLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIV 69
LL A+G++GL +LL V V P +K+GIV DAGSSHTS+F+Y+W A+KEN TG+V
Sbjct: 13 LLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV 72
Query: 70 GQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLN 129
Q +C V G GISSY N + A +SL GCLE+AL +P+ +H TP +LGATAGMRLL+
Sbjct: 73 SQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLS 132
Query: 130 LTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRW 189
N + + AVT L + P DF GA +L+GQ EG FGW+T NY L +KY + G W
Sbjct: 133 RKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEW 192
Query: 190 FRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQV 248
+P + L GA+D+GGASTQITF P D++++ LYG Y VYTHS+LC+GRDQ+
Sbjct: 193 IQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQM 252
Query: 249 LQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGS 304
L RLL +Q+ HPC+ G+ T + LG +Y+SPC A P + + +++ G+
Sbjct: 253 LSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQN--LTVEGT 310
Query: 305 SDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPV 363
+P C + LF+FSSC C+F+GV+QPP+ G F AFS F+YT FL + P+
Sbjct: 311 GNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPL 370
Query: 364 ATLQQLEAAAVNVCNQTW-----------------------AQQLLSRGYGFDERAFGGV 400
+T + A C + W LL GYGF E + +
Sbjct: 371 ST---VNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSL 427
Query: 401 IFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLL 460
F+K+A +GW LGYMLNLT +IPAD P + + WV ++ AL+A + L
Sbjct: 428 EFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAAL 487
Query: 461 RQV 463
Q+
Sbjct: 488 VQL 490
>gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [Homo
sapiens]
Length = 529
Score = 369 bits (947), Expect = e-102
Identities = 194/480 (40%), Positives = 282/480 (58%), Gaps = 36/480 (7%)
Query: 12 LLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQ 71
LL++ L + ++ + ++V PP LKYGIVLDAGSS T++++Y+WPA+KEN+TG+V Q
Sbjct: 30 LLVSIVVLVSITVIQIHKQEVL-PPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQ 88
Query: 72 HSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLT 131
C V G GISSY +NP ++ C+++ VP H TP++LGATAGMRLL L
Sbjct: 89 TFKCSVKGSGISSYGNNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQ 148
Query: 132 NPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFR 191
N A+ VL ++ PFDFRGA+I+SGQEEGV+GW+TANYL+ NF++ W
Sbjct: 149 NETAANEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVH 208
Query: 192 PR-KGTLGAMDLGGASTQITFETTSPAEDRASEV-QLHLYGQHYRVYTHSFLCYGRDQVL 249
P T GA+DLGGASTQI+F + S++ Q+ LYG Y +YTHSF CYGR++
Sbjct: 209 PHGVETTGALDLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAE 268
Query: 250 QRLLASALQ-----THGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGS 304
++ LA LQ H +PC+PR +S +G V+ S CT+ QRP+++N + ++ G+
Sbjct: 269 KKFLAMLLQNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGT 328
Query: 305 SDPHLCRDLVSGLFSFSSC-PFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPV 363
DP LC++ V+ +F F +C CSF+GV+QP + G FVAF+ F+YT L S
Sbjct: 329 GDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASALNLSGSF-- 386
Query: 364 ATLQQLEAAAVNVCNQTWAQ------------------------QLLSRGYGFDERAFGG 399
+L ++ N C+Q W+Q L GY F E +
Sbjct: 387 -SLDTFNSSTWNFCSQNWSQLPLLLPKFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQ 445
Query: 400 VIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLL 459
+ F+K+ ++++ W+LGYML+LTN IPA+ P +R + +V L F +A L L L
Sbjct: 446 IHFEKEVGNSSIAWSLGYMLSLTNQIPAESPLIRLPIEPPVFVGTLAFFTAAALLCLAFL 505
>gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8
isoform 2 [Homo sapiens]
Length = 458
Score = 363 bits (933), Expect = e-100
Identities = 196/462 (42%), Positives = 274/462 (59%), Gaps = 32/462 (6%)
Query: 13 LLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIV 69
LL A+G++GL +LL V V P +K+GIV DAGSSHTS+F+Y+W A+KEN TG+V
Sbjct: 13 LLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV 72
Query: 70 GQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLN 129
Q +C V G GISSY N + A +SL GCLE+AL +P+ +H TP +LGATAGMRLL+
Sbjct: 73 SQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLS 132
Query: 130 LTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRW 189
N + + AVT L + P DF GA +L+GQ EG FGW+T NY L +KY + G W
Sbjct: 133 RKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEW 192
Query: 190 FRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQV 248
+P + L GA+D+GGASTQITF P D++++ LYG Y VYTHS+LC+GRDQ+
Sbjct: 193 IQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQM 252
Query: 249 LQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGS 304
L RLL +Q+ HPC+ G+ T + LG +Y+SPC A P + + +++ G+
Sbjct: 253 LSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQN--LTVEGT 310
Query: 305 SDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYTVDFLR--TSMGL 361
+P C + LF+FSSC C+F+GV+QPP+ G F +++ +LR + GL
Sbjct: 311 GNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYVEASYPGQDRWLRDYCASGL 370
Query: 362 PVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNL 421
+ T LL GYGF E + + F+K+A +GW LGYMLNL
Sbjct: 371 YILT-------------------LLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNL 411
Query: 422 TNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQV 463
T +IPAD P + + WV ++ AL+A + L Q+
Sbjct: 412 TGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAALVQL 453
>gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1
isoform 2 [Homo sapiens]
Length = 517
Score = 335 bits (859), Expect = 5e-92
Identities = 193/493 (39%), Positives = 275/493 (55%), Gaps = 52/493 (10%)
Query: 7 SLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDT 66
S++ + L A GL T++ P +KYGIVLDAGSSHTS++IYKWPA+KENDT
Sbjct: 32 SIIAVIALLAVGL---------TQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKENDT 82
Query: 67 GIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMR 126
G+V Q C V G GIS + + L C+E+A + +P+ +H TP+YLGATAGMR
Sbjct: 83 GVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMR 142
Query: 127 LLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWV 186
LL + + E + VL V +L+ YPFDF+GARI++GQEEG +GW+T NYLL K+
Sbjct: 143 LLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLG---KFSQK 199
Query: 187 GRWF------RPRKGTLGAMDLGGASTQITF-ETTSPAEDRASEVQLHLYGQHYRVYTHS 239
RWF + T GA+DLGGASTQ+TF E + +Q LYG+ Y VYTHS
Sbjct: 200 TRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHS 259
Query: 240 FLCYGRDQVLQRLLASALQTHGFH----PCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNS 295
FLCYG+DQ L + LA +Q PC+ G+ V + D+Y++PCT +R +
Sbjct: 260 FLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCT--KRFEMTLP 317
Query: 296 SARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFL 355
+ + G + C + LF+ S CP+S+C+FNG+F PP+ G+F AFSAF++ + FL
Sbjct: 318 FQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFL 377
Query: 356 RTSMGLPVATLQQLEAAAVNVCNQTWAQ------------------------QLLSRGYG 391
++ + +++ C Q W + LL +GY
Sbjct: 378 --NLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYH 435
Query: 392 FDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASA 451
F ++ + F K + GW LGYMLNLTN+IPA+ P L S++V L++LF+
Sbjct: 436 FTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQP-LSTPLSHSTYVFLMVLFSLV 494
Query: 452 LLAALVLLLRQVH 464
L ++ L H
Sbjct: 495 LFTVAIIGLLIFH 507
>gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1
isoform 1 [Homo sapiens]
Length = 510
Score = 335 bits (859), Expect = 5e-92
Identities = 193/493 (39%), Positives = 275/493 (55%), Gaps = 52/493 (10%)
Query: 7 SLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDT 66
S++ + L A GL T++ P +KYGIVLDAGSSHTS++IYKWPA+KENDT
Sbjct: 25 SIIAVIALLAVGL---------TQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKENDT 75
Query: 67 GIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMR 126
G+V Q C V G GIS + + L C+E+A + +P+ +H TP+YLGATAGMR
Sbjct: 76 GVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMR 135
Query: 127 LLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWV 186
LL + + E + VL V +L+ YPFDF+GARI++GQEEG +GW+T NYLL K+
Sbjct: 136 LLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLG---KFSQK 192
Query: 187 GRWF------RPRKGTLGAMDLGGASTQITF-ETTSPAEDRASEVQLHLYGQHYRVYTHS 239
RWF + T GA+DLGGASTQ+TF E + +Q LYG+ Y VYTHS
Sbjct: 193 TRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHS 252
Query: 240 FLCYGRDQVLQRLLASALQTHGFH----PCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNS 295
FLCYG+DQ L + LA +Q PC+ G+ V + D+Y++PCT +R +
Sbjct: 253 FLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCT--KRFEMTLP 310
Query: 296 SARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFL 355
+ + G + C + LF+ S CP+S+C+FNG+F PP+ G+F AFSAF++ + FL
Sbjct: 311 FQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFL 370
Query: 356 RTSMGLPVATLQQLEAAAVNVCNQTWAQ------------------------QLLSRGYG 391
++ + +++ C Q W + LL +GY
Sbjct: 371 --NLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYH 428
Query: 392 FDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASA 451
F ++ + F K + GW LGYMLNLTN+IPA+ P L S++V L++LF+
Sbjct: 429 FTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQP-LSTPLSHSTYVFLMVLFSLV 487
Query: 452 LLAALVLLLRQVH 464
L ++ L H
Sbjct: 488 LFTVAIIGLLIFH 500
>gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4
isoform b [Homo sapiens]
Length = 608
Score = 130 bits (328), Expect = 2e-30
Identities = 110/384 (28%), Positives = 168/384 (43%), Gaps = 47/384 (12%)
Query: 36 PALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSYAD 87
P + YGIV+D GSS + +F+Y WP N ++ D GIS +A
Sbjct: 85 PNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFAT 144
Query: 88 NPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTL 147
+P S + L A + VP+ +H TPLY+ TAGMR+L + +A L+
Sbjct: 145 SPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVH 204
Query: 148 TQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKY-------------GWVGRWFRPRK 194
+ F A ++SG++EGV+ W+ N++L F G RK
Sbjct: 205 FDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRK 264
Query: 195 GTLGAMDLGGASTQITFE---TTSPAEDRASEVQL----HLYGQHYRVYTHSFLCYG--- 244
T G +D+GG STQI +E T A++ +E L H YRVY +FL +G
Sbjct: 265 RTAGILDMGGVSTQIAYEVPKTEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNA 324
Query: 245 -RDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSAR-VSLS 302
R + R+ A+ +Q + G T + Y PC + + + L
Sbjct: 325 ARQRYEDRIFANTIQKNRL-----LGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLR 379
Query: 303 GSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPV---AGNFVAFSAFFY-TVDFLRTS 358
G+ D LCR+ + + ++ ++ S NGV+QPP+ F FS F+Y T D LR
Sbjct: 380 GTGDFDLCRETIQPFMNKTN--ETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMG 437
Query: 359 MGLPVATLQQLEAAAVNVCNQTWA 382
A + AA + C W+
Sbjct: 438 GDYNAA---KFTKAAKDYCATKWS 458
>gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isoform
a [Homo sapiens]
Length = 616
Score = 130 bits (327), Expect = 3e-30
Identities = 111/392 (28%), Positives = 169/392 (43%), Gaps = 55/392 (14%)
Query: 36 PALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSYAD 87
P + YGIV+D GSS + +F+Y WP N ++ D GIS +A
Sbjct: 85 PNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFAT 144
Query: 88 NPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTL 147
+P S + L A + VP+ +H TPLY+ TAGMR+L + +A L+
Sbjct: 145 SPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVH 204
Query: 148 TQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKY-------------GWVGRWFRPRK 194
+ F A ++SG++EGV+ W+ N++L F G RK
Sbjct: 205 FDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRK 264
Query: 195 GTLGAMDLGGASTQITFE---TTSPAEDRASEVQLHLYGQH------------YRVYTHS 239
T G +D+GG STQI +E T S A + EV +L + YRVY +
Sbjct: 265 RTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVAT 324
Query: 240 FLCYG----RDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNS 295
FL +G R + R+ A+ +Q + G T + Y PC
Sbjct: 325 FLGFGGNAARQRYEDRIFANTIQKNRL-----LGKQTGLTPDMPYLDPCLPLDIKDEIQQ 379
Query: 296 SAR-VSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPV---AGNFVAFSAFFY- 350
+ + + L G+ D LCR+ + + ++ ++ S NGV+QPP+ F FS F+Y
Sbjct: 380 NGQTIYLRGTGDFDLCRETIQPFMNKTN--ETQTSLNGVYQPPIHFQNSEFYGFSEFYYC 437
Query: 351 TVDFLRTSMGLPVATLQQLEAAAVNVCNQTWA 382
T D LR A + AA + C W+
Sbjct: 438 TEDVLRMGGDYNAA---KFTKAAKDYCATKWS 466
>gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Homo
sapiens]
Length = 604
Score = 124 bits (310), Expect = 2e-28
Identities = 138/501 (27%), Positives = 208/501 (41%), Gaps = 91/501 (18%)
Query: 34 EPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSY 85
E P L YG+V+D GSS + +F+Y WP N ++ D GIS+
Sbjct: 78 EDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAM 137
Query: 86 ADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTH 145
AD P AS L L A VP ++H TPLY+ TAGMRLL PE ++A
Sbjct: 138 ADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLL----PERKQLAILADLV 193
Query: 146 TLTQYPFDF----RGARILSGQEEGVFGWVTANYLLENF-----IKYGWVGRWFRPRKGT 196
FDF A ++SG++EGV+ W+ N++L F R+ T
Sbjct: 194 KDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRT 253
Query: 197 LGAMDLGGASTQITFETTS-----PA-EDRASEVQLHLYG-----QH----YRVYTHSFL 241
+G +D+GGAS QI +E + PA ++ A+++ L + QH YRVY +FL
Sbjct: 254 VGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFL 313
Query: 242 CYGRDQVLQR----LLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSA 297
+G + QR +L L + G T + + + PC ++
Sbjct: 314 GFGGNFARQRYEDLVLNETLNKNRL-----LGQKTGLSPDNPFLDPCLPVGLTDVVERNS 368
Query: 298 RV-SLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGN---FVAFSAFFY-TV 352
+V + G D C ++S L + S+ S+ S NG++Q P+ N F FS FFY T
Sbjct: 369 QVLHVRGRGDWVSCGAMLSPLLARSNT--SQASLNGIYQSPIDFNNSEFYGFSEFFYCTE 426
Query: 353 DFLRTSMGLPVATLQQLEAAAVNVCNQTWA------------------------------ 382
D LR T + AA + C W+
Sbjct: 427 DVLRIGGRYHGPTFAK---AAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWM 483
Query: 383 QQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIP---ADPPGLRKGTDFS 439
Q+L G+ F + + + D V W LG +L T +P G+R+
Sbjct: 484 YQVLHEGFHF-PYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQA--HG 540
Query: 440 SWVVLLLLFASALLAALVLLL 460
SW L ++ L A +L++
Sbjct: 541 SWFRLSFVYNHYLFFACILVV 561
>gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Homo
sapiens]
Length = 428
Score = 111 bits (278), Expect = 1e-24
Identities = 111/416 (26%), Positives = 168/416 (40%), Gaps = 78/416 (18%)
Query: 40 YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC 99
YGI+ DAGS+ T + +Y + I+ + D G+S++ D P ++++ G
Sbjct: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPIL-EGEVFDSVKPGLSAFVDQPKQGAETVQGL 107
Query: 100 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPE-ASTSVLMAVTHTLTQYPF--DFRG 156
LE A +P+ TP+ L ATAG+RLL PE + ++L V + PF
Sbjct: 108 LEVAKDSIPRSHWKKTPVVLKATAGLRLL----PEHKAKALLFEVKEIFRKSPFLVPKGS 163
Query: 157 ARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQIT----FE 212
I+ G +EG+ WVT N+L G+ R+ T+G +DLGGASTQIT FE
Sbjct: 164 VSIMDGSDEGILAWVTVNFL---------TGQLHGHRQETVGTLDLGGASTQITFLPQFE 214
Query: 213 TTSPAEDRASEVQLHLYGQHYRVYTHSFLCYG----RDQVLQRLLASALQTHGFH-PCWP 267
T R ++ Y++YTHS+L +G R L L H F C P
Sbjct: 215 KTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLP 274
Query: 268 RGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSC--PF 325
R + + G V + G+ + G F C
Sbjct: 275 RWLEAEWIFGGV------------------KYQYGGNQE---------GEVGFEPCYAEV 307
Query: 326 SRCSFNGVFQPPVA--GNFVAFSAFF---YTVDFLRTSMGLPVATLQQLEAAAVNVCNQ- 379
R + QP G+F AFS ++ D + G + ++ E A VC+
Sbjct: 308 LRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKG-GILKVEDFERKAREVCDNL 366
Query: 380 --------------TWAQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNL 421
++ LL G+GF + + KK + GWALG +L
Sbjct: 367 ENFTSGSPFLCMDLSYITALLKDGFGFADSTV--LQLTKKVNNIETGWALGATFHL 420
>gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6
isoform 2 [Homo sapiens]
Length = 467
Score = 93.6 bits (231), Expect = 3e-19
Identities = 66/211 (31%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 40 YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC 99
YGI+ DAGS+ T + ++++ + H + G+S+YAD+ ++Q +
Sbjct: 85 YGIMFDAGSTGTRVHVFQFTRPPRETPTLT--HETFKALKPGLSAYADDVEKSAQGIREL 142
Query: 100 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRG--A 157
L+ A QD+P + TPL L ATAG+RLL E + +L V PF
Sbjct: 143 LDVAKQDIPFDFWKATPLVLKATAGLRLL---PGEKAQKLLQKVKEVFKASPFLVGDDCV 199
Query: 158 RILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITF----ET 213
I++G +EGV W+T N+L G P ++G +DLGG STQI F E
Sbjct: 200 SIMNGTDEGVSAWITINFL---------TGSLKTPGGSSVGMLDLGGGSTQIAFLPRVEG 250
Query: 214 TSPAEDRASEVQLHLYGQHYRVYTHSFLCYG 244
T A L ++ + Y++Y++S+L G
Sbjct: 251 TLQASPPGYLTALRMFNRTYKLYSYSYLGLG 281
>gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6
isoform 1 [Homo sapiens]
Length = 484
Score = 93.6 bits (231), Expect = 3e-19
Identities = 66/211 (31%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 40 YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC 99
YGI+ DAGS+ T + ++++ + H + G+S+YAD+ ++Q +
Sbjct: 102 YGIMFDAGSTGTRVHVFQFTRPPRETPTLT--HETFKALKPGLSAYADDVEKSAQGIREL 159
Query: 100 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRG--A 157
L+ A QD+P + TPL L ATAG+RLL E + +L V PF
Sbjct: 160 LDVAKQDIPFDFWKATPLVLKATAGLRLL---PGEKAQKLLQKVKEVFKASPFLVGDDCV 216
Query: 158 RILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITF----ET 213
I++G +EGV W+T N+L G P ++G +DLGG STQI F E
Sbjct: 217 SIMNGTDEGVSAWITINFL---------TGSLKTPGGSSVGMLDLGGGSTQIAFLPRVEG 267
Query: 214 TSPAEDRASEVQLHLYGQHYRVYTHSFLCYG 244
T A L ++ + Y++Y++S+L G
Sbjct: 268 TLQASPPGYLTALRMFNRTYKLYSYSYLGLG 298
>gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo
sapiens]
Length = 870
Score = 29.6 bits (65), Expect = 6.2
Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 277 GDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQP 336
G VY + ++ Q + S + GS HLC L++GL S CP S C ++
Sbjct: 165 GPVYTTSPSLHQGEPSLVSEFTAASQGSVR-HLC-SLLAGLSSLFRCPISSCYTLSLYNT 222
Query: 337 PVAGNFV 343
++G+ +
Sbjct: 223 SISGSLL 229
>gi|239743315 PREDICTED: hypothetical protein XP_002342820 [Homo
sapiens]
Length = 248
Score = 29.6 bits (65), Expect = 6.2
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 15/110 (13%)
Query: 28 PTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVP--------- 78
P R V +++ + L+AG S F W A + + G G +P
Sbjct: 15 PWRTVGCSGSIQASLALEAGVSMLPTF---WTAWSQQEQGAAGAGVRVALPQVEELGRHD 71
Query: 79 GGGISSYADNPSGASQSLV--GCLEQALQDVPKERHAGTPLYLGATAGMR 126
GGG + A + + GC +A VP+ R G+PL LG+ R
Sbjct: 72 GGGEEAQAQEAGDGDERYILEGC-GRARAGVPQTRAPGSPLPLGSVPDPR 120
>gi|239508997 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 29.6 bits (65), Expect = 6.2
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 15/110 (13%)
Query: 28 PTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVP--------- 78
P R V +++ + L+AG S F W A + + G G +P
Sbjct: 15 PWRTVGCSGSIQASLALEAGVSMLPTF---WTAWSQQEQGAAGAGVRVALPQVEELGRHD 71
Query: 79 GGGISSYADNPSGASQSLV--GCLEQALQDVPKERHAGTPLYLGATAGMR 126
GGG + A + + GC +A VP+ R G+PL LG+ R
Sbjct: 72 GGGEEAQAQEAGDGDERYILEGC-GRARAGVPQTRAPGSPLPLGSVPDPR 120
>gi|5032105 small optic lobes [Homo sapiens]
Length = 1086
Score = 29.6 bits (65), Expect = 6.2
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 109 KERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVF 168
+ RHA + L + G RLL L NP S + + +P RG + G EGVF
Sbjct: 714 RPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVF 773
Query: 169 GWVTANYLLENFIKY 183
W+ +F++Y
Sbjct: 774 -WMEYG----DFVRY 783
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,280,075
Number of Sequences: 37866
Number of extensions: 805759
Number of successful extensions: 1739
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1675
Number of HSP's gapped (non-prelim): 21
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.