Guide to the Human Genome
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Search of human proteins with 45505161

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45505161 leukocyte specific transcript 1 isoform 2 [Homo
sapiens]
         (75 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45505161 leukocyte specific transcript 1 isoform 2 [Homo sapi...   162   7e-41
gi|45505165 leukocyte specific transcript 1 isoform 1 [Homo sapi...   158   1e-39
gi|45580740 leukocyte specific transcript 1 isoform 4 [Homo sapi...   138   1e-33
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]          35   0.017
gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]            33   0.050
gi|239753510 PREDICTED: hypothetical protein [Homo sapiens]            30   0.42 
gi|239742053 PREDICTED: hypothetical protein XP_002342380 [Homo ...    30   0.42 
gi|6912446 potassium voltage-gated channel, subfamily H, member ...    27   2.7  
gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Ho...    27   4.6  
gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Ho...    27   4.6  
gi|239757960 PREDICTED: hypothetical protein [Homo sapiens]            27   4.6  
gi|239742474 PREDICTED: hypothetical protein [Homo sapiens]            27   4.6  
gi|116292168 KRAB A domain containing 1 [Homo sapiens]                 26   6.1  
gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [H...    26   7.9  
gi|4504573 inhibitor of DNA binding 4, dominant negative helix-l...    26   7.9  

>gi|45505161 leukocyte specific transcript 1 isoform 2 [Homo
          sapiens]
          Length = 75

 Score =  162 bits (409), Expect = 7e-41
 Identities = 75/75 (100%), Positives = 75/75 (100%)

Query: 1  MMPRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHL 60
          MMPRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHL
Sbjct: 1  MMPRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHL 60

Query: 61 PQPRRVDRVPLWSSQ 75
          PQPRRVDRVPLWSSQ
Sbjct: 61 PQPRRVDRVPLWSSQ 75


>gi|45505165 leukocyte specific transcript 1 isoform 1 [Homo
           sapiens]
          Length = 118

 Score =  158 bits (399), Expect = 1e-39
 Identities = 73/73 (100%), Positives = 73/73 (100%)

Query: 3   PRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQ 62
           PRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQ
Sbjct: 46  PRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQ 105

Query: 63  PRRVDRVPLWSSQ 75
           PRRVDRVPLWSSQ
Sbjct: 106 PRRVDRVPLWSSQ 118


>gi|45580740 leukocyte specific transcript 1 isoform 4 [Homo
          sapiens]
          Length = 63

 Score =  138 bits (347), Expect = 1e-33
 Identities = 63/63 (100%), Positives = 63/63 (100%)

Query: 13 MHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQPRRVDRVPLW 72
          MHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQPRRVDRVPLW
Sbjct: 1  MHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQPRRVDRVPLW 60

Query: 73 SSQ 75
          SSQ
Sbjct: 61 SSQ 63


>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
          Length = 414

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 17/33 (51%), Positives = 20/33 (60%)

Query: 31  AETREAPRRIQELTMPALLRTNPPEHPRHLPQP 63
           A  +EA RR QEL M  L  T+PPE  R+ P P
Sbjct: 238 APLKEAARRAQELEMEMLSSTSPPERTRYSPIP 270


>gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]
          Length = 443

 Score = 33.1 bits (74), Expect = 0.050
 Identities = 16/29 (55%), Positives = 18/29 (62%)

Query: 35  EAPRRIQELTMPALLRTNPPEHPRHLPQP 63
           EA RR QEL M  L  T+PPE  R+ P P
Sbjct: 271 EAARRAQELEMEMLSSTSPPERTRYSPIP 299


>gi|239753510 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 284

 Score = 30.0 bits (66), Expect = 0.42
 Identities = 12/20 (60%), Positives = 14/20 (70%)

Query: 42  ELTMPALLRTNPPEHPRHLP 61
           EL + ALL + PP HP HLP
Sbjct: 121 ELLVEALLTSKPPAHPSHLP 140


>gi|239742053 PREDICTED: hypothetical protein XP_002342380 [Homo
           sapiens]
          Length = 311

 Score = 30.0 bits (66), Expect = 0.42
 Identities = 12/20 (60%), Positives = 14/20 (70%)

Query: 42  ELTMPALLRTNPPEHPRHLP 61
           EL + ALL + PP HP HLP
Sbjct: 148 ELLVEALLTSKPPAHPSHLP 167


>gi|6912446 potassium voltage-gated channel, subfamily H, member 4
           [Homo sapiens]
          Length = 1017

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/51 (29%), Positives = 23/51 (45%)

Query: 3   PRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNP 53
           PR  Q R+ ++        P++ +  SGAE    PR  + L +P L    P
Sbjct: 704 PRLSQPRSESLGSSSDKTLPSITEAESGAEPGGGPRPRRPLLLPNLSPARP 754


>gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
           sapiens]
          Length = 880

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 25  RDLTSGAETREAPRRIQELTMPALLRTNPP---EHPRHLPQPRRVDRVPLW 72
           R L   ++T    RR   L  P     +PP   +  R LPQP+   ++P W
Sbjct: 441 RSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSW 491


>gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
           sapiens]
          Length = 880

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 25  RDLTSGAETREAPRRIQELTMPALLRTNPP---EHPRHLPQPRRVDRVPLW 72
           R L   ++T    RR   L  P     +PP   +  R LPQP+   ++P W
Sbjct: 441 RSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSW 491


>gi|239757960 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 292

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 29 SGAETREAPRRIQELTMP-ALLRTNPPEHPRHLPQPRR 65
          +GA  R A R++     P +L RT+   HP H P P R
Sbjct: 13 AGAGRRPAARQVAPPGGPXSLARTHSRRHPDHAPPPGR 50


>gi|239742474 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 589

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 17/68 (25%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 3   PRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQ 62
           PR P+  ++  H  RG +  AVR++ +  +       ++E+    L R   P  PR    
Sbjct: 217 PRGPRQGSTDKHTERGVRVGAVREVPTSTQRGGRVGAVREVRTSTLER--GPRGPRQGST 274

Query: 63  PRRVDRVP 70
            +  +R P
Sbjct: 275 DKHTERGP 282


>gi|116292168 KRAB A domain containing 1 [Homo sapiens]
          Length = 1030

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 14/42 (33%), Positives = 17/42 (40%)

Query: 22  PAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQP 63
           P V + + G E      R+   T   LL   PPE P   P P
Sbjct: 731 PRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPP 772


>gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [Homo
           sapiens]
          Length = 1016

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 6/59 (10%)

Query: 1   MMPRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRH 59
           ++P A + + S + LC     P V+DL  G E  + P  +  L     LR  PP    H
Sbjct: 692 LLPAAGELQESGLALC-----PEVQDLLEGCELPDLPSSLL-LPEDMALRNLPPLRAAH 744


>gi|4504573 inhibitor of DNA binding 4, dominant negative
           helix-loop-helix protein [Homo sapiens]
          Length = 161

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 15/31 (48%), Positives = 15/31 (48%), Gaps = 3/31 (9%)

Query: 44  TMPALLRTNPPEHPRHLPQ---PRRVDRVPL 71
           T PALLR  PP  P H P    P    R PL
Sbjct: 110 THPALLRQPPPPAPPHHPAGTCPAAPPRTPL 140


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.132    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,774,934
Number of Sequences: 37866
Number of extensions: 160319
Number of successful extensions: 542
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 533
Number of HSP's gapped (non-prelim): 15
length of query: 75
length of database: 18,247,518
effective HSP length: 47
effective length of query: 28
effective length of database: 16,467,816
effective search space: 461098848
effective search space used: 461098848
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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