Search of human proteins with 4507693

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo
sapiens]
         (1164 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]     2340   0.0  
gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens]   2334   0.0  
gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens]   2216   0.0  
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             74   6e-13
gi|16262452 cingulin [Homo sapiens]                                    68   4e-11
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    68   6e-11
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]        64   1e-09
gi|210032790 hypothetical protein LOC27146 [Homo sapiens]              63   1e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    62   4e-09
gi|38044112 restin isoform b [Homo sapiens]                            62   4e-09
gi|4506751 restin isoform a [Homo sapiens]                             62   4e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    62   4e-09
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    62   4e-09
gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]        61   5e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    60   9e-09
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...    60   1e-08
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C...    60   1e-08
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    60   2e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    59   2e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    59   2e-08
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        59   2e-08
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        59   2e-08
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         59   2e-08
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         59   2e-08
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         59   2e-08
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         59   2e-08
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         59   2e-08
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         59   2e-08
gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-l...    58   5e-08
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   58   5e-08

>gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]
          Length = 1164

 Score = 2340 bits (6064), Expect = 0.0
 Identities = 1164/1164 (100%), Positives = 1164/1164 (100%)

Query: 1    MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI 60
            MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI
Sbjct: 1    MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI 60

Query: 61   LTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCL 120
            LTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCL
Sbjct: 61   LTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCL 120

Query: 121  KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL 180
            KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL
Sbjct: 121  KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL 180

Query: 181  HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH 240
            HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH
Sbjct: 181  HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH 240

Query: 241  ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT 300
            ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT
Sbjct: 241  ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT 300

Query: 301  QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT 360
            QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT
Sbjct: 301  QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT 360

Query: 361  SPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR 420
            SPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR
Sbjct: 361  SPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR 420

Query: 421  KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA 480
            KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA
Sbjct: 421  KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA 480

Query: 481  AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL 540
            AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL
Sbjct: 481  AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL 540

Query: 541  DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ 600
            DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ
Sbjct: 541  DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ 600

Query: 601  PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH 660
            PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH
Sbjct: 601  PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH 660

Query: 661  SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 720
            SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL
Sbjct: 661  SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 720

Query: 721  RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR 780
            RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR
Sbjct: 721  RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR 780

Query: 781  QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES 840
            QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES
Sbjct: 781  QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES 840

Query: 841  VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ 900
            VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ
Sbjct: 841  VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ 900

Query: 901  RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
            RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL
Sbjct: 901  RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT 1020
            EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT
Sbjct: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT 1020

Query: 1021 PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS 1080
            PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS
Sbjct: 1021 PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS 1080

Query: 1081 LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP 1140
            LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP
Sbjct: 1081 LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP 1140

Query: 1141 SPPTPDSVGQLHIMDYNETHHEHS 1164
            SPPTPDSVGQLHIMDYNETHHEHS
Sbjct: 1141 SPPTPDSVGQLHIMDYNETHHEHS 1164


>gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens]
          Length = 1163

 Score = 2334 bits (6048), Expect = 0.0
 Identities = 1163/1164 (99%), Positives = 1163/1164 (99%), Gaps = 1/1164 (0%)

Query: 1    MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI 60
            MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI
Sbjct: 1    MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI 60

Query: 61   LTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCL 120
            LTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCL
Sbjct: 61   LTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCL 120

Query: 121  KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL 180
            KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL
Sbjct: 121  KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL 180

Query: 181  HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH 240
            HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH
Sbjct: 181  HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH 240

Query: 241  ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT 300
            ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT
Sbjct: 241  ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT 300

Query: 301  QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT 360
            QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT
Sbjct: 301  QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT 360

Query: 361  SPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR 420
            SPGNVPPDLSHPYSKVFGTT GGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR
Sbjct: 361  SPGNVPPDLSHPYSKVFGTT-GGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR 419

Query: 421  KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA 480
            KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA
Sbjct: 420  KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA 479

Query: 481  AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL 540
            AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL
Sbjct: 480  AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL 539

Query: 541  DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ 600
            DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ
Sbjct: 540  DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ 599

Query: 601  PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH 660
            PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH
Sbjct: 600  PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH 659

Query: 661  SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 720
            SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL
Sbjct: 660  SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 719

Query: 721  RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR 780
            RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR
Sbjct: 720  RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR 779

Query: 781  QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES 840
            QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES
Sbjct: 780  QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES 839

Query: 841  VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ 900
            VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ
Sbjct: 840  VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ 899

Query: 901  RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
            RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL
Sbjct: 900  RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 959

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT 1020
            EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT
Sbjct: 960  EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT 1019

Query: 1021 PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS 1080
            PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS
Sbjct: 1020 PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS 1079

Query: 1081 LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP 1140
            LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP
Sbjct: 1080 LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP 1139

Query: 1141 SPPTPDSVGQLHIMDYNETHHEHS 1164
            SPPTPDSVGQLHIMDYNETHHEHS
Sbjct: 1140 SPPTPDSVGQLHIMDYNETHHEHS 1163


>gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens]
          Length = 1113

 Score = 2216 bits (5742), Expect = 0.0
 Identities = 1113/1164 (95%), Positives = 1113/1164 (95%), Gaps = 51/1164 (4%)

Query: 1    MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI 60
            MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI
Sbjct: 1    MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHI 60

Query: 61   LTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCL 120
            LTTLQEPHD                                                   
Sbjct: 61   LTTLQEPHD--------------------------------------------------- 69

Query: 121  KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL 180
            KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL
Sbjct: 70   KMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHL 129

Query: 181  HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH 240
            HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH
Sbjct: 130  HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH 189

Query: 241  ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT 300
            ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT
Sbjct: 190  ELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADT 249

Query: 301  QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT 360
            QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT
Sbjct: 250  QNSYGCATSTPYSTSRLMLLNMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPT 309

Query: 361  SPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR 420
            SPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR
Sbjct: 310  SPGNVPPDLSHPYSKVFGTTAGGKGTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPR 369

Query: 421  KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA 480
            KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA
Sbjct: 370  KEERMDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLASEEDSIEKDKEEA 429

Query: 481  AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL 540
            AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL
Sbjct: 430  AISRELSEITTAEAEPVVPRGGFDSPFYRDSLPGSQRKTHSAASSSQGASVNPEPLHSSL 489

Query: 541  DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ 600
            DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ
Sbjct: 490  DKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQ 549

Query: 601  PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH 660
            PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH
Sbjct: 550  PPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAH 609

Query: 661  SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 720
            SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL
Sbjct: 610  SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 669

Query: 721  RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR 780
            RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR
Sbjct: 670  RKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIR 729

Query: 781  QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES 840
            QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES
Sbjct: 730  QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES 789

Query: 841  VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ 900
            VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ
Sbjct: 790  VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQ 849

Query: 901  RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
            RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL
Sbjct: 850  RLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 909

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT 1020
            EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT
Sbjct: 910  EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKT 969

Query: 1021 PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS 1080
            PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS
Sbjct: 970  PRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGS 1029

Query: 1081 LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP 1140
            LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP
Sbjct: 1030 LPSSKSFLGMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHP 1089

Query: 1141 SPPTPDSVGQLHIMDYNETHHEHS 1164
            SPPTPDSVGQLHIMDYNETHHEHS
Sbjct: 1090 SPPTPDSVGQLHIMDYNETHHEHS 1113


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 101/400 (25%), Positives = 180/400 (45%), Gaps = 41/400 (10%)

Query: 618 HFVIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLP--LPSKSVD 675
           H  + +TE  L +A G  +E    S+   +++D+  QQ AD   K L++L   L  K  +
Sbjct: 420 HSKLLETERQLGEAHGRLKEQRQLSSE--KLMDKE-QQVADLQLK-LSRLEEQLKEKVTN 475

Query: 676 WTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRN--RRLLRKVIKAAALEEHN 733
            T         + +    Q L    Q    + +  Q+ L    R++  K  K   LE   
Sbjct: 476 STELQHQLDKTKQQHQEQQAL---QQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALL 532

Query: 734 AAMKDQLKLQEKDIQMWKVSLQK---EQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFY 790
              K+ + L EK+ +     +Q    E A  NQLQE+  T    L  Q+ QL    E+  
Sbjct: 533 QKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHT----LQEQVTQLT---EKLK 585

Query: 791 NQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEF--- 847
           NQS+  +   E+  + + E +  L+ A ++V   E  +++++ +L+ S+    Q++    
Sbjct: 586 NQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIK 645

Query: 848 LNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQK 907
              +LL+  E  +         H DT +     K   ++EL K  + + Q T +L   Q+
Sbjct: 646 AKTELLLSAEAAKTAQRADLQNHLDTAQNALQDK---QQELNKITTQLDQVTAKLQDKQE 702

Query: 908 RILELESHLA--KKDHLLLEQK--------KYLEDVKLQARGQLQAAESRYEAQKRITQV 957
              +LESHL   K+ +L LEQK        K LE   L+ +   + A    + Q+++   
Sbjct: 703 HCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTD 762

Query: 958 FELEILDLYGRLEKDGLL---KKLE-EEKAEAAEAAEERL 993
            EL   +L  +LE +  +    +L+ ++K+EA E+ +++L
Sbjct: 763 LELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKL 802



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 77/360 (21%), Positives = 162/360 (45%), Gaps = 36/360 (10%)

Query: 624 TEELLKKAKGNT---EEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFG 680
           TE LLKK +  T   E+    S S   +   L Q+  D    + ++L     S+   H  
Sbjct: 308 TENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQ-SRLSASETSLHRIHVE 366

Query: 681 GSPPSDEIRTLRDQLLLLHN----------QLLYERFKRQQHALRNR----RLLRKVIKA 726
            S   +  + L+++L  +            QL  +R +++QH L+ +    +L  K+++ 
Sbjct: 367 LSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLET 426

Query: 727 AA-LEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQ---RDTMVTKLHSQIRQL 782
              L E +  +K+Q +L  + +   +  +   Q + ++L+EQ   + T  T+L  Q+ + 
Sbjct: 427 ERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKT 486

Query: 783 QHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQ 842
           +   +E     Q    KL + +N + ++  ++   + K+ + E LL +  + +S  E  +
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKER 546

Query: 843 QQMEFLNRQLLVLGEVNELYLEQLQNKH-------SDTTKEVEMMKAAYRKELEKNRSHV 895
           + +       +  GE     L QLQ K+       +  T++++    ++++  E     V
Sbjct: 547 EDL----YAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQV 602

Query: 896 LQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQ---LQAAESRYEAQK 952
            +Q   L  +Q R+L LE+ + + +  L E K+ +  + +Q + +   L +AE+   AQ+
Sbjct: 603 QEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQR 662



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 80/387 (20%), Positives = 162/387 (41%), Gaps = 33/387 (8%)

Query: 621  IRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFG 680
            ++K  E L+  K    +         +  + L Q+    H +  N++      +      
Sbjct: 788  LQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKME 847

Query: 681  GSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQL 740
                  E+ T++D+L  + + L   + + ++   + +  +  + K     +H   ++ + 
Sbjct: 848  KEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMEN 907

Query: 741  KLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKL---HSQIRQLQHDREEFYNQSQELQ 797
             L+E+  +  K SL+KE+   +QL+ + ++M  +L    + ++Q + + ++      EL+
Sbjct: 908  TLKEQ--KELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELK 965

Query: 798  TKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGE 857
               E  +  I  L+ ELK A   V     L +++ Q+L+ +    Q++     ++ VL  
Sbjct: 966  QSSEQKKKQIEALQGELKIA---VLQKTELENKLQQQLTQAA---QELAAEKEKISVLQN 1019

Query: 858  VNELYLEQLQNKHSD-------------TTKEVEMMKAAYRKELEKNRSHVLQQTQRLDT 904
              E   E  +   SD               K VE   +  +++L  NR+ +  Q + +  
Sbjct: 1020 NYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQE 1079

Query: 905  SQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILD 964
             +     LE   AKK+  L E+ K L+D+  Q    L+  E   E  K        EI +
Sbjct: 1080 LKTAKATLEQDSAKKEQQLQERCKALQDI--QKEKSLKEKELVNEKSKL------AEIEE 1131

Query: 965  LYGRLEKDGLLKKLEEEKAEAAEAAEE 991
            +  R EK+ + K  EE K+   E+ +E
Sbjct: 1132 IKCRQEKE-ITKLNEELKSHKLESIKE 1157



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 60/271 (22%), Positives = 121/271 (44%), Gaps = 31/271 (11%)

Query: 741 KLQEKDIQMWKVSLQKEQARYNQLQEQRD----------TMVTKLHSQI----RQLQHDR 786
           KL+E ++   +   Q  +A + QLQ+QR+          + + +LHS++    RQL    
Sbjct: 376 KLKE-ELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAH 434

Query: 787 EEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQME 846
                Q Q    KL D    +A+L+++L +   ++       +++  +L  ++   Q+ +
Sbjct: 435 GRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQ 494

Query: 847 FLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKE------LEKNRSHVLQQTQ 900
            L +         +  LEQ+  +  D  ++++ ++A  +K       LEK R  +  + Q
Sbjct: 495 ALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQ 554

Query: 901 RLDTSQKRILELESHLAKKDHLLLEQKKYL-EDVKLQARGQLQAAES---RYEAQKRITQ 956
                +  +L   + L +K+H L EQ   L E +K Q+    QA E+   + + QK   +
Sbjct: 555 -AGEGETAVL---NQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLR 610

Query: 957 VFELEILDLYGRLEKDGLLKKLEEEKAEAAE 987
             +  +L L   + +  L  +L E K + ++
Sbjct: 611 AAQDRVLSLETSVNE--LNSQLNESKEKVSQ 639



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 61/316 (19%), Positives = 140/316 (44%), Gaps = 32/316 (10%)

Query: 687  EIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKD 746
            E+ ++++QL+   N L     + QQ        L+  I    L++ +   K Q++  + +
Sbjct: 932  ELNSMQEQLIQAQNTLKQNEKEEQQ--------LQGNINE--LKQSSEQKKKQIEALQGE 981

Query: 747  IQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQ---IRQLQHDREEFYNQSQELQTKLEDC 803
            +   K+++ ++    N+LQ+Q      +L ++   I  LQ++ E+     ++LQ+     
Sbjct: 982  L---KIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGR 1038

Query: 804  RNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYL 863
             + +   R +LK    K+   +  L     ++ N   + Q+++     L    E +    
Sbjct: 1039 ESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATL----EQDSAKK 1094

Query: 864  EQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLA------ 917
            EQ   +     ++++  K+   KEL   +S + +  +     +K I +L   L       
Sbjct: 1095 EQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLES 1154

Query: 918  -KKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLK 976
             K+   L + K+ L   KL+ +G+  + ++  E +KR  Q+ + ++     + E++ L K
Sbjct: 1155 IKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQV-----KKEEEELKK 1209

Query: 977  KLEEEKAEAAEAAEER 992
            +  E++A+     +E+
Sbjct: 1210 EFIEKEAKLHSEIKEK 1225



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 77/357 (21%), Positives = 158/357 (44%), Gaps = 40/357 (11%)

Query: 618 HFVIRKTEELL--KKAKGNTEEDGVPSTSPME-VLDRLIQQGADAHSKELNKLPLPSKSV 674
           +F I++ ++L   K A+  TE   + S    E  L    +Q     ++ELNK     + +
Sbjct: 151 NFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDL 210

Query: 675 DWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNA 734
             T     P  +++  L+ +L+ +   +     +R++ + + +   +K+    A  E   
Sbjct: 211 K-TELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATI 269

Query: 735 A-MKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQS 793
           + ++ +L    +++ ++   LQK ++  N+L ++  T+   L          +E+ Y   
Sbjct: 270 SQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLK--------KEQDY--- 318

Query: 794 QELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLL 853
               TKLE+  N   E  +  K     +   +L   Q+  +LS SE+    +  ++ +L 
Sbjct: 319 ----TKLEEKHN---EESVSKKNIQATLHQKDLDCQQLQSRLSASET---SLHRIHVELS 368

Query: 854 VLGEVNELYLEQLQNKHSDTTKEVEMMKAAYR---KELEKNRSHVLQQTQRLDTSQKRIL 910
             GE  +   E+L    S+   + + +KA ++   ++ E+   H LQ    ++    ++L
Sbjct: 369 EKGEATQKLKEEL----SEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLL 424

Query: 911 ELESHLAKKDHLLLEQKKYLEDVKLQARGQ----LQAAESRYEAQ--KRITQVFELE 961
           E E  L +  H  L++++ L   KL  + Q    LQ   SR E Q  +++T   EL+
Sbjct: 425 ETERQLGEA-HGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQ 480



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 60/284 (21%), Positives = 129/284 (45%), Gaps = 23/284 (8%)

Query: 687  EIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEK- 745
            +++++ ++L L    L+  R           +L++++  A A  E ++A K+Q +LQE+ 
Sbjct: 1048 DLKSVEEKLSLAQEDLISNR----NQIGNQNKLIQELKTAKATLEQDSAKKEQ-QLQERC 1102

Query: 746  ----DIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLE 801
                DIQ  K   +KE         + + +  +   +I +L  + +    +S +  T L+
Sbjct: 1103 KALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLK 1162

Query: 802  DCRNMIAELRIELK-KANN--KVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEV 858
            D + ++ + ++EL+ KA++       E    Q+ +     E  + + EF+ ++  +  E+
Sbjct: 1163 DAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEI 1222

Query: 859  NELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAK 918
             E   E    KH +   ++ M   A    L +N   V ++ Q   +SQ+R+ ELE     
Sbjct: 1223 KE--KEVGMKKHEENEAKLTMQITA----LNENLGTVKKEWQ---SSQRRVSELEKQTDD 1273

Query: 919  KDHLLLEQKKYLEDVKLQARGQLQ-AAESRYEAQKRITQVFELE 961
                +   +  +++ + + R  L+   +   E +K  T+V EL+
Sbjct: 1274 LRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQ 1317



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 74/315 (23%), Positives = 129/315 (40%), Gaps = 67/315 (21%)

Query: 731 EHNAAMK-DQLKLQEKDIQMWKVSLQ----------KEQARYNQLQEQR---DTMVTKLH 776
           E N A+K D + L  +++Q  + SL+          KE  +Y  LQ+Q    D +VT   
Sbjct: 75  ESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSS 134

Query: 777 SQIRQLQHDREE--------------FYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
           ++++ L+   EE              F  ++ +L T++ D ++   E R   + A  KV 
Sbjct: 135 AELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVT 194

Query: 823 H----------------TELLLSQVSQKLS--NSESVQQQMEFLNRQLLVLGEVNELYLE 864
                            TELL     + ++    E VQ Q    N  L    E  +L  E
Sbjct: 195 RLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDE 254

Query: 865 --QLQNKHSDTTKEVEMMK----------AAYRKELEKNRSHVLQQTQRLDTSQKRILEL 912
             +LQ++++ +   +  ++          A Y +EL+K +S V + TQ+  T  + +L+ 
Sbjct: 255 CKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKK 314

Query: 913 ESHLAKKDHLLLEQ---KKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRL 969
           E    K +    E+   KK ++    Q     Q  +SR  A +       +E+       
Sbjct: 315 EQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVEL------S 368

Query: 970 EKDGLLKKLEEEKAE 984
           EK    +KL+EE +E
Sbjct: 369 EKGEATQKLKEELSE 383


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 89/392 (22%), Positives = 176/392 (44%), Gaps = 38/392 (9%)

Query: 623 KTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADA-HSKELNKLPLPSKSVDWTHFGG 681
           + +ELL++ KG  ++    S   ++ + RL+ QG D  H  E   + L +K     H  G
Sbjct: 405 RLQELLERRKGEAQQ----SNKELQNMKRLLDQGEDLRHGLETQVMELQNKL---KHVQG 457

Query: 682 SPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKA--AALEEHNAAMKDQ 739
             P+ E+  L+D  LL   +LL E  + +Q      RL  + + A   AL+E  A+   +
Sbjct: 458 PEPAKEV-LLKD--LLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQE 514

Query: 740 LK----LQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQE 795
           ++      ++D +  + S+Q     +  L+ +R  M   +    R+L+   EE  +    
Sbjct: 515 VEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSM 574

Query: 796 LQTKLEDCR---NMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQL 852
            Q   ED R     + +LR+E ++   ++     +L +  ++   S    +Q+E L ++L
Sbjct: 575 FQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKEL 634

Query: 853 L-VLGEVNELYLE----QLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQK 907
           L    E+ EL  E    ++  +H D  +E+E   A  R E ++ R    Q  Q   T Q+
Sbjct: 635 LRTQEELKELQAERQSQEVAGRHRD--RELEKQLAVLRVEADRGRELEEQNLQLQKTLQQ 692

Query: 908 RILELE-----SHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEI 962
              + E       +A+ +  +L Q++   +  L+     +  E   E ++RI  + E ++
Sbjct: 693 LRQDCEEASKAKMVAEAEATVLGQRRAAVETTLR-----ETQEENDEFRRRILGL-EQQL 746

Query: 963 LDLYGRLEKDGLLKKLEEEKAEAAEAAEERLD 994
            +  G ++    ++    +K +  EA +++L+
Sbjct: 747 KETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 778



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 82/325 (25%), Positives = 138/325 (42%), Gaps = 32/325 (9%)

Query: 687 EIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKD 746
           ++  L+ +LL    +L   + +RQ   +  R   R++ K  A+    A    +L  +E++
Sbjct: 626 QVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGREL--EEQN 683

Query: 747 IQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNM 806
           +Q+ K     +Q R +  +  +  MV +  + +  L   R       +E Q + ++ R  
Sbjct: 684 LQLQKTL---QQLRQDCEEASKAKMVAEAEATV--LGQRRAAVETTLRETQEENDEFRRR 738

Query: 807 IAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQM-EFLNR------QLLVLGEVN 859
           I  L  +LK+    V   E + +++  KL   E+ +QQ+ E LN        L       
Sbjct: 739 ILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRAL 798

Query: 860 ELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKK 919
           E  LE+ Q   +   +E + +  A   E E  +  VL++ +     QKR+L+        
Sbjct: 799 EARLEEAQRGLARLGQEQQTLNRAL--EEEGKQREVLRRGKAELEEQKRLLD-----RTV 851

Query: 920 DHLLLEQKKYLEDVKLQARGQLQAAESRY-EAQKRITQVFELEILDLYGRLEK-DGLLKK 977
           D L  E +K  ED K QA  QLQA    Y E  +R     + +  D     EK  G L +
Sbjct: 852 DRLNKELEKIGEDSK-QALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSR 910

Query: 978 LEEE--------KAEAAEAAEERLD 994
           L++E        +A  AE    RLD
Sbjct: 911 LQDEIQRLRQALQASQAERDTARLD 935



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 64/305 (20%), Positives = 126/305 (41%), Gaps = 29/305 (9%)

Query: 717  RRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLH 776
            R+L  +V K   LE     ++ QL+ + ++    +  L++ +    Q  ++   M  +L 
Sbjct: 373  RKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQSNKELQNM-KRLL 431

Query: 777  SQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLS 836
             Q   L+H  E    Q  ELQ KL+  +       + LK     +  T  LL +V   L 
Sbjct: 432  DQGEDLRHGLE---TQVMELQNKLKHVQGPEPAKEVLLKD----LLETRELLEEV---LE 481

Query: 837  NSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVL 896
              + V++Q+    R+L  L          L+ + +   +EVE ++  Y+++ E+ R  + 
Sbjct: 482  GKQRVEEQLRLRERELTALKGA-------LKEEVASRDQEVEHVRQQYQRDTEQLRRSMQ 534

Query: 897  QQTQR---LDTSQKRIL--------ELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAE 945
              TQ    L+  ++++         ELE    +  H     +K  ED++   +  LQ   
Sbjct: 535  DATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRM 594

Query: 946  SRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMV 1005
             + E ++ + +  E+   +L       G  +++E  K E     EE  +   +  S  + 
Sbjct: 595  EKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVA 654

Query: 1006 GHNEE 1010
            G + +
Sbjct: 655  GRHRD 659



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 88/374 (23%), Positives = 151/374 (40%), Gaps = 62/374 (16%)

Query: 623  KTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGS 682
            K  E+L++ K   EE             RL+ +  D  +KEL K+   SK          
Sbjct: 828  KQREVLRRGKAELEEQ-----------KRLLDRTVDRLNKELEKIGEDSKQA-------- 868

Query: 683  PPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKL 742
                 ++ L+ QL         E +K +  A R     ++  K  A E    +    L  
Sbjct: 869  -----LQQLQAQL---------EDYKEK--ARREVADAQRQAKDWASEAEKTS--GGLSR 910

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
             + +IQ  + +LQ  QA  +  +  ++ +  +L      L+ + E       +   +L+ 
Sbjct: 911  LQDEIQRLRQALQASQAERDTARLDKELLAQRLQG----LEQEAENKKRSQDDRARQLKG 966

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQM--EFLNRQLLVLGEVNE 860
                ++ L  EL +  N V   ELL  +V++     + ++ ++  E   RQ L   E ++
Sbjct: 967  LEEKVSRLETELDEEKNTV---ELLTDRVNRGRDQVDQLRTELMQERSARQDL---ECDK 1020

Query: 861  LYLEQLQNKHSDT---TKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLA 917
            + LE+ QNK   T   + E     +A   +LE +++ +LQ+  RL   ++    L+S   
Sbjct: 1021 ISLER-QNKDLKTRLASSEGFQKPSASLSQLE-SQNQLLQE--RLQAEEREKTVLQSTNR 1076

Query: 918  KKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKK 977
            K +  + E    +ED +     Q      R +A KR     E EI  L      DGL KK
Sbjct: 1077 KLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERL------DGLRKK 1130

Query: 978  LEEEKAEAAEAAEE 991
             + E  E  E  E+
Sbjct: 1131 AQREVEEQHEVNEQ 1144



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 9/141 (6%)

Query: 652  LIQQGADAHSKELNKLPLPSKSVDW-----THFGGSPPSDEIRTLRDQLLLLHNQLLYER 706
            L+Q+ +     E +K+ L  ++ D      +  G   PS  +  L  Q  LL  +L  E 
Sbjct: 1006 LMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEE 1065

Query: 707  FKRQQHALRNRRLLRKV----IKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYN 762
             ++      NR+L RKV    I+     +H    KDQL L+ K ++      ++E  R +
Sbjct: 1066 REKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERLD 1125

Query: 763  QLQEQRDTMVTKLHSQIRQLQ 783
             L+++    V + H    QLQ
Sbjct: 1126 GLRKKAQREVEEQHEVNEQLQ 1146


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 87/397 (21%), Positives = 180/397 (45%), Gaps = 60/397 (15%)

Query: 640 VPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLH 699
           V  +S  ++ ++++Q     +S+EL KL +  K+ ++  F G+  S  ++  +++  L  
Sbjct: 99  VGGSSEYKINNKVVQ--LHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFE 156

Query: 700 N-----QLLYERFKRQQ-------------HALRNRRLLRKVIKAAALE-EHNAAMKDQL 740
                 +L  E  KR++             H  +N    RK  K    E +    +KD++
Sbjct: 157 EISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEV 216

Query: 741 KLQEKDIQMWKV--------SLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQ 792
              +  +Q++K+         L KE A  N+  E+    + K+  ++++ + +  +   +
Sbjct: 217 VRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMRE 276

Query: 793 SQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQ----MEFL 848
            Q+++ ++++  + + + R +  KA     H    L    + L N++   ++    M+ L
Sbjct: 277 QQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDEL 336

Query: 849 NRQLLVLGEVNELYLEQL----QNKHSDTTKEVEMMKAAYR--KELEKNRSHVLQQTQRL 902
            +++L + +  + + E++    Q++  D T E   +K  +R  +E  K  + + Q+ ++ 
Sbjct: 337 EKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKF 396

Query: 903 DTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEI 962
           +  QK         A +D L LE++K +E  + + + +L+  E   E QKRI      E 
Sbjct: 397 NRDQK---------ADQDRLDLEERKKVE-TEAKIKQKLREIE---ENQKRI------EK 437

Query: 963 LDLYGRLEKDGL--LKKLEEEKAEAAEAAEERLDCCN 997
           L+ Y    K  L   KKLE E  E  E A+ R+D  N
Sbjct: 438 LEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEIN 474



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 46/250 (18%), Positives = 118/250 (47%), Gaps = 24/250 (9%)

Query: 737  KDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQEL 796
            K+QLK  +  + MW+ +++K++    +L+++    +  +   + QLQ    +  NQ    
Sbjct: 825  KNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQ----DLKNQHLAK 880

Query: 797  QTKLEDCRNMIAELRIELKKANNKVCHTE----LLLSQVSQKLSNSESVQQQMEFLNRQL 852
            ++++ D  + + E+R +L  AN ++ H +     + +++ QK S+  ++ Q  +  + +L
Sbjct: 881  KSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKL 940

Query: 853  -LVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKEL------------EKNRSHVLQQT 899
             L  G ++++  E+  ++  D+    + + + Y +E              K+     +  
Sbjct: 941  PLSKGTMDDISQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAEEEIK 1000

Query: 900  QRLDTSQKRILELES---HLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQ 956
            Q ++T Q+++ E +S    +A  +   +E+ + + D   +   + +AA  R +  K+  +
Sbjct: 1001 QEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFE 1060

Query: 957  VFELEILDLY 966
              + E  D +
Sbjct: 1061 QIKKERFDRF 1070



 Score = 31.2 bits (69), Expect = 6.0
 Identities = 44/156 (28%), Positives = 75/156 (48%), Gaps = 33/156 (21%)

Query: 859 NELYLEQLQNKHSDTTKEVEMMKAAYRKELE----KNRSHVLQQTQRLDTSQKRILELES 914
           +E  +++L+ K    T+E++    A RKE E    ++++H LQ   RL  SQ  + + ++
Sbjct: 667 DEKAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQ--MRLKYSQSDLEQTKT 724

Query: 915 -HLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLE--K 971
            HLA    L L++K  LE        +L     R    KRI Q  E E+ DL  ++   +
Sbjct: 725 RHLA----LNLQEKSKLE-------SELANFGPRINDIKRIIQSREREMKDLKEKMNQVE 773

Query: 972 DGL------------LKKLEEEKAEAA-EAAEERLD 994
           D +            +++ EEEK +   E A++RL+
Sbjct: 774 DEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLE 809


>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
          Length = 841

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 75/310 (24%), Positives = 133/310 (42%), Gaps = 40/310 (12%)

Query: 688 IRTLRDQLLL--LHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEK 745
           +R L+DQ+ +     Q   E    + +ALR           AALE+   A   +L +  +
Sbjct: 310 LRALQDQVSIQSADAQEQVEGLLAENNALRT--------SLAALEQIQTAKTQELNMLRE 361

Query: 746 DIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRN 805
                   LQ++QA Y  L  Q+D     L+SQ+++          Q QE+  + E    
Sbjct: 362 QTTGLAAELQQQQAEYEDLMGQKD----DLNSQLQESLRANSRLLEQLQEIGQEKEQLTQ 417

Query: 806 MIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQ 865
            + E R   +K   K    EL +  + +K  + E +      L  +  VLG V   Y  +
Sbjct: 418 ELQEARKSAEK--RKAMLDELAMETLQEKSQHKEELGAVR--LRHEKEVLG-VRARYERE 472

Query: 866 LQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLE 925
           L+  H D  ++ E ++   R+E  +        T+ L+T Q+ + EL++ +    H +  
Sbjct: 473 LRELHEDKKRQEEELRGQIREEKAR--------TRELETLQQTVEELQAQV----HSMDG 520

Query: 926 QKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEA 985
            K + E    +A   LQ  + + E ++ + Q  E    +L G+ E      +L++ + + 
Sbjct: 521 AKGWFERRLKEAEESLQ--QQQQEQEEALKQCREQHAAELKGKEE------ELQDVRDQL 572

Query: 986 AEAAEERLDC 995
            +A EER DC
Sbjct: 573 EQAQEER-DC 581



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 77/329 (23%), Positives = 142/329 (43%), Gaps = 38/329 (11%)

Query: 681 GSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQL 740
           G PP     T+   + L   +L +E  K ++  L  +    + ++++   E +   ++  
Sbjct: 173 GDPPGGPAPTVLAPMPLAEVELKWEMEKEEKRLLWEQL---QGLESSKQAETSRLQEELA 229

Query: 741 KLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYN----QSQEL 796
           KL EK        L+K+Q  + +LQ +++T+     ++I +LQ  +E  +     ++Q+L
Sbjct: 230 KLSEK--------LKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKL 281

Query: 797 QTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQME-------FLN 849
           Q +LE     +AELR +  +   ++ H   L +   Q    S   Q+Q+E        L 
Sbjct: 282 QQELEAANQSLAELRDQ--RQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALR 339

Query: 850 RQLLVLGEVNELYLEQLQNKHSDTT---KEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQ 906
             L  L ++     ++L      TT    E++  +A Y ++L   +  +  Q Q    + 
Sbjct: 340 TSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEY-EDLMGQKDDLNSQLQESLRAN 398

Query: 907 KRILE-LESHLAKKDHL---LLEQKKYLEDVKLQ----ARGQLQAAESRYEAQKRITQVF 958
            R+LE L+    +K+ L   L E +K  E  K      A   LQ      E    +    
Sbjct: 399 SRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRH 458

Query: 959 ELEILDLYGRLEKDGLLKKLEEEKAEAAE 987
           E E+L +  R E++  L++L E+K    E
Sbjct: 459 EKEVLGVRARYERE--LRELHEDKKRQEE 485


>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
          Length = 1060

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 76/330 (23%), Positives = 150/330 (45%), Gaps = 36/330 (10%)

Query: 669 LPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAA 728
           LP +S +     G  P  +   L  Q L + NQ L + + R+   L+           A 
Sbjct: 176 LPQESPETKSEPGQGPEMQEVLLEVQRLRVENQQLSKDYARKAEELQ-----------AT 224

Query: 729 LEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYN-QLQEQRDTMVTKLHSQIRQLQHDRE 787
            E  N A++  ++ Q     +W+   ++   R N Q+QE      + L +Q+R+L+ D E
Sbjct: 225 YERENEAIRQAMQ-QSVSQALWQWQEKESDLRKNFQVQE------SALQAQVRKLEGDLE 277

Query: 788 EFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQ----- 842
               +  +L+   +  +  I +L ++LK+A  +    +    ++ +KL+ ++        
Sbjct: 278 HRGRKISDLKKYAQKLKERIQDLDVQLKEARQENSELKGTAKKLGEKLAVAKDRMMLQEC 337

Query: 843 ---QQMEFLNRQLL----VLGEVNELYLEQLQNKHSDT-TKEVEMMKAAYRKELEKNRSH 894
              QQ + +  +L+    VL E N+L    L  +   +  KE   MK     + +K  S 
Sbjct: 338 RGTQQTDAMKTELVSENKVLREENDLEAGNLHPQQDQSCLKECPCMKGGTDMQTKKEASA 397

Query: 895 VLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQ-KR 953
             +  ++      R ++ ++   KK HL  +  K LED+  +   ++++  S  EA+ K+
Sbjct: 398 ETEYMKQQYEEDLRKIKHQTEEEKK-HLKDQLVKRLEDLVKKHTVEIKSVRSSVEAERKK 456

Query: 954 ITQVFELEILDLYGRLEKDGLLKKLEEEKA 983
           + +  E ++ ++  + EK+  +K+LEEEKA
Sbjct: 457 LQREVEAQLEEVRKKSEKE--IKQLEEEKA 484



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 90/402 (22%), Positives = 163/402 (40%), Gaps = 67/402 (16%)

Query: 686  DEIRTLRDQLL-----LLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQL 740
            +E + L+DQL+     L+    +  +  R       ++L R+V   A LEE     + ++
Sbjct: 419  EEKKHLKDQLVKRLEDLVKKHTVEIKSVRSSVEAERKKLQREV--EAQLEEVRKKSEKEI 476

Query: 741  KLQEKDIQMWKVSLQK---EQARYNQLQEQRDTMVTKLHSQIRQL--QH----------- 784
            K  E++     V LQ    E  R  +  +Q  T  T      ++L  QH           
Sbjct: 477  KQLEEEKAALNVKLQNSLLEVLRLEEFIQQNKTRPTGAEESPQELGRQHCSILETQDPCL 536

Query: 785  DREEFYNQSQELQTKL-----------EDCRNMIAE-------LRIELKKANNKVCHTE- 825
              +E   + +E Q KL           E  + ++ E       L   LK+  +K+   E 
Sbjct: 537  KLDETSPRGEEYQDKLAAEEGTSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSKIQRLEE 596

Query: 826  -------LLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE 878
                    L +QVSQ     ++++Q        L  L ++++L  E+LQ +  +TT++  
Sbjct: 597  DWQSQKAKLQAQVSQM---QQALEQCTSNYREDLQALKQLSDLEREKLQRELQETTQQNH 653

Query: 879  MMKAAYRKELEKNRSHVLQ-----QTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
             MKA    +LE +    L+     + Q L  +++R+ +  SH  +  H     +  L+ +
Sbjct: 654  AMKA----QLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQH--QTHRLELQAL 707

Query: 934  KLQARGQLQAAESRYEAQKR-ITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEER 992
            + +AR +LQ    R +AQ+  + +    E+ +        G  K LE  +AE      ++
Sbjct: 708  EEKARQELQEERERMQAQQALLLESLRQELSEQQAAC--SGHQKDLEALQAELRALGRQQ 765

Query: 993  LDCCNDGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRG 1034
                  G S   +   EE  G  G+  +P  ++ +GS    G
Sbjct: 766  ASSQCPGDSKDHIIATEERGG-PGQAGSPPGAAGQGSGEGCG 806



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 63/241 (26%), Positives = 100/241 (41%), Gaps = 45/241 (18%)

Query: 701 QLLYERFKRQQHALRNRRLLRKVIKAAA--LEEHNAAMKDQLKLQEKDIQMWKVSLQKEQ 758
           Q L ER +     L+  R     +K  A  L E  A  KD++ LQE              
Sbjct: 291 QKLKERIQDLDVQLKEARQENSELKGTAKKLGEKLAVAKDRMMLQE-------------- 336

Query: 759 ARYNQLQEQRDTMVTKLHSQIRQL--QHDREEFYNQSQELQTKLEDCRNMIAELRIELKK 816
            R  Q   Q D M T+L S+ + L  ++D E      Q+ Q+ L++C  M     ++ KK
Sbjct: 337 CRGTQ---QTDAMKTELVSENKVLREENDLEAGNLHPQQDQSCLKECPCMKGGTDMQTKK 393

Query: 817 ANNKVCHTELLLSQVSQKLSN-SESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK 875
             +    TE +  Q  + L       +++ + L  QL+         LE L  KH+   K
Sbjct: 394 EAS--AETEYMKQQYEEDLRKIKHQTEEEKKHLKDQLVKR-------LEDLVKKHTVEIK 444

Query: 876 EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKL 935
            V     A RK+L++     L++ ++   S+K I +LE            ++K   +VKL
Sbjct: 445 SVRSSVEAERKKLQREVEAQLEEVRK--KSEKEIKQLE------------EEKAALNVKL 490

Query: 936 Q 936
           Q
Sbjct: 491 Q 491


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 80/412 (19%), Positives = 183/412 (44%), Gaps = 45/412 (10%)

Query: 602 PPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTE-EDGVPSTSPMEVLDRLIQQGADAH 660
           P + HL     P    H ++ K     K A+   +  D  P T+P      +    +D  
Sbjct: 34  PTHPHL--PTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPS-----VGTAASDTK 86

Query: 661 SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 720
            K++N    P  +   T  G   P DE +         H + L    + Q H +R     
Sbjct: 87  KKKINNGTNPETT---TSGGCHSPEDEQKASHQ-----HQEALRRELEAQVHTIRILTCQ 138

Query: 721 RKVIKAAALEEHNAAMKDQLKLQEKDI-----QMWKVSLQKEQA------------RY-N 762
           +  ++ A     +A    QL+ + +D+       WK + + EQA            RY  
Sbjct: 139 KTELQMALYYSQHAVK--QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIE 196

Query: 763 QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
           +L ++RD +  +L+   R    D EE   ++ +LQ KL+   +  +E+++ +K+   K+ 
Sbjct: 197 ELTKERDALSLELY---RNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 252

Query: 823 HTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKA 882
             +LLL Q  Q  + ++ + ++++ ++ +L    E NEL+    Q +     ++ E ++ 
Sbjct: 253 RAKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ- 310

Query: 883 AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQ 942
            + +++++    + +Q +++   ++++   E  + +K+  +  Q++ + + + + R Q +
Sbjct: 311 EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 370

Query: 943 AAESRYEAQKRITQVF---ELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEE 991
               + E  +R  ++    E +I +L  ++ +   +++ EE++ E  +  E+
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 54/316 (17%), Positives = 141/316 (44%), Gaps = 27/316 (8%)

Query: 686 DEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEK 745
           +E+   +++ +    ++++E+ ++ +          K+ +     +    +++Q K QE+
Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 428

Query: 746 DIQMWKVSLQKEQARYNQLQEQRDTM---VTKLHSQIR----QLQHDREEFYNQSQELQT 798
           + +MW+   +K + +  +++EQ   M     K+H Q +    + + ++EE + Q +++  
Sbjct: 429 EAKMWRQE-EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487

Query: 799 KLEDCRNM--IAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLG 856
           + E  R    + E   +++K   KV   E  + +  +K+   E    + E   R+   + 
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547

Query: 857 EVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHL 916
              E   EQ +    +  +E E       +++ +    V +Q +++   +++  E E  +
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607

Query: 917 AKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLK 976
            K++  + EQ++ +++ + + R Q    E +   Q+ +TQ             E++  + 
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQ----EEKIREQEEMTQ-------------EQEEKMG 650

Query: 977 KLEEEKAEAAEAAEER 992
           + EE+  E  E  +E+
Sbjct: 651 EQEEKMCEQEEKMQEQ 666



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 38/225 (16%), Positives = 97/225 (43%), Gaps = 31/225 (13%)

Query: 733 NAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQ 792
           N   ++++  QE+ IQ W+  +Q+++ +  + +E+      K+  Q   +    E+   Q
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354

Query: 793 SQELQTKLEDCR---NMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLN 849
            + +  K E  R    M+ E   ++++    +   E  + ++ +K+   E +++Q E   
Sbjct: 355 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE--- 411

Query: 850 RQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRI 909
                                    K  E  K   +++ ++  + + +Q +++   +++I
Sbjct: 412 -------------------------KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446

Query: 910 LELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRI 954
            E E  + +++  + EQ+K  E+ K Q + ++   E +   Q+ I
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 51/273 (18%), Positives = 124/273 (45%), Gaps = 27/273 (9%)

Query: 698 LHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKE 757
           +H Q    R K + H    +  +RK  +    +E     +++ K++E++ +MW+   Q+E
Sbjct: 485 IHEQEEIWRQKEKMHEQEEK--IRKQEEKVWRQEEKIREQEE-KIREQEEKMWR---QEE 538

Query: 758 QARYNQLQEQRDTMVTKLHSQIR-----QLQHDREEFYNQSQELQTKLEDCRNMIAELRI 812
           + R    QE+      K+H Q +     + Q   ++ + Q ++++ + E       ++R 
Sbjct: 539 KIRE---QEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595

Query: 813 ELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSD 872
           + +K   +    E +  Q  +     E +Q+Q E +  Q   + E  E+  EQ +     
Sbjct: 596 QEEKRQEQ---EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652

Query: 873 TTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL-- 930
             K  E       +++++    + +Q +++   +K+I E E  + +++ ++ EQ++ +  
Sbjct: 653 EEKMCEQ-----EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707

Query: 931 -EDVKLQARGQLQAAESRYEAQKRITQVFELEI 962
            E+   +   ++Q  E +   Q+   +++E E+
Sbjct: 708 QEEKMCEQEEKMQEQEEKMRRQEE--KMWEQEV 738



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 46/300 (15%), Positives = 134/300 (44%), Gaps = 15/300 (5%)

Query: 705 ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQL 764
           E+ + Q+  +R +  +    +     +     + + K++ ++  MW+   +++  R  ++
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKMRRQEEM 385

Query: 765 QEQRDTMVTKLHSQIRQLQHDREEFYNQSQEL----QTKLEDCRNMIAELRIELKKANNK 820
             +++  + +L  ++ + +  RE+   + +E     Q K ++    +     ++++   K
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445

Query: 821 VCHTELLLSQVSQKLSNSESV-----QQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK 875
           +   E  + +  +K+   E +     +Q+ E + RQ   + E  E++  Q +  H    K
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW-RQKEKMHEQEEK 504

Query: 876 EVEMMKAAYRKE--LEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
             +  +  +R+E  + +    + +Q +++   +++I E E    +++ +  ++K + E+ 
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEK 564

Query: 934 KLQARGQLQAAESRYEAQKRITQVFELEILDL-YGRLEKDGLLKKLEEEKAEAAEAAEER 992
           + +   ++   E +   Q+      E +I +    R E++  + K EE+  E  E  +E+
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQ 624


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 68/326 (20%), Positives = 143/326 (43%), Gaps = 31/326 (9%)

Query: 682  SPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALR----NRRLLRKVIKAAALEEHNAAMK 737
            S    E++ LR QL     Q+ +   ++   + +     R L  + +K   L+E+ + + 
Sbjct: 738  SEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVS 797

Query: 738  DQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQ 797
               +  EK++Q+ K    +       +Q      V KLH +        E+F   S +L+
Sbjct: 798  QVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQK-------EEQFNMLSSDLE 850

Query: 798  TKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGE 857
               E+  +M A+ R + ++    +   E L + +++ +  S     Q+  +N +L     
Sbjct: 851  KLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL----R 906

Query: 858  VNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLA 917
            + E  +E+LQ K +   +    ++ +      K      +  ++ +  +K +    S L 
Sbjct: 907  LKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE 966

Query: 918  KKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRL-----EKD 972
            KK      +  + +  +L+AR +   +E++ + ++ I Q  +  +LD   +L     E  
Sbjct: 967  KK-----METSHNQCQELKARYERATSETKTKHEE-ILQNLQKTLLDTEDKLKGAREENS 1020

Query: 973  GLLKKLEE-----EKAEAAEAAEERL 993
            GLL++LEE     +KA+AA+ AE+ +
Sbjct: 1021 GLLQELEELRKQADKAKAAQTAEDAM 1046



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 65/318 (20%), Positives = 139/318 (43%), Gaps = 24/318 (7%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAA----MKDQL 740
            S ++  LR+ L  +  +   +  + +Q      +L   + +   +   N++    M D+L
Sbjct: 846  SSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 905

Query: 741  KLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQ----IRQLQHDREEFYNQSQEL 796
            +L+E+D++  ++ L K     + LQ+  + M  K         ++ + +++E   +  +L
Sbjct: 906  RLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDL 965

Query: 797  QTKLEDCRNMIAELRIELKKANN--KVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLV 854
            + K+E   N   EL+   ++A +  K  H E+L +     L   + ++   E       +
Sbjct: 966  EKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGARE---ENSGL 1022

Query: 855  LGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKE-------LEKNRSHVLQQTQRLDTSQK 907
            L E+ EL  +  + K + T ++   +     KE       LE  +    +    LDT ++
Sbjct: 1023 LQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKE 1082

Query: 908  RILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYG 967
              L+    L K   LL  + + +E+ + +     QAA  + + Q    Q   +++ +  G
Sbjct: 1083 NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQ-QLSALQEENVKLAEELG 1141

Query: 968  RLEKDGLL--KKLEEEKA 983
            R  +D +   +KLEEE++
Sbjct: 1142 R-SRDEVTSHQKLEEERS 1158



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 63/319 (19%), Positives = 130/319 (40%), Gaps = 44/319 (13%)

Query: 711  QHALRNRRLLRKVIKAAALEEHNAAMKDQLK-LQEKDIQMWKVSLQKEQARYNQLQEQRD 769
            QH + N +  +   +AA  +E  A     +K ++EK+  +  +  + ++A    L E  D
Sbjct: 625  QHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMED 684

Query: 770  TMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLS 829
            T+     ++I+           + + LQ K  +   +I     +LK    K+   + L  
Sbjct: 685  TLNKLQEAEIK---------VKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRK 735

Query: 830  QVSQKLSNSESVQQQMEFLNRQLLVLG-----------------EVNELYLEQLQNKHSD 872
              S+  S  + ++QQ+E   +Q+  L                  +  EL L  LQ    +
Sbjct: 736  ASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQ----E 791

Query: 873  TTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHL-------LLE 925
               EV  +K    KEL+  +    + ++   + Q+ + E  + L +K+         L +
Sbjct: 792  NLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEK 851

Query: 926  QKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEE---K 982
             ++ L D++ + R + +  E   +A++++      EI+ + G  +    L K+ +E   K
Sbjct: 852  LRENLADMEAKFREKDEREEQLIKAKEKLENDI-AEIMKMSG--DNSSQLTKMNDELRLK 908

Query: 983  AEAAEAAEERLDCCNDGCS 1001
                E  + +L   N+  S
Sbjct: 909  ERDVEELQLKLTKANENAS 927



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 44/228 (19%), Positives = 94/228 (41%), Gaps = 20/228 (8%)

Query: 794  QELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLL 853
            + L+ K +    ++AE  +E  +      H   +  +++      +    ++E    QL 
Sbjct: 355  EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLR 414

Query: 854  VLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKE-LEKNRSHVLQQTQRLDTSQKRILEL 912
             + E  +    +L N+  +  ++VE ++    +E + K    V   +++      RI+EL
Sbjct: 415  TMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEK-----SRIMEL 469

Query: 913  ESHLAKKDHLLLEQKKYLE--------DVKLQARGQLQAAESRYEAQKRITQVFELEILD 964
            E  LA +   + E ++ LE        D+ L    ++ + + + E  +   Q    EI  
Sbjct: 470  EKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQ---REITS 526

Query: 965  LYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEAS 1012
            L    E  G  ++  +++ +A   A E+L   N+     +   N+E S
Sbjct: 527  L---KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENS 571


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 68/326 (20%), Positives = 143/326 (43%), Gaps = 31/326 (9%)

Query: 682  SPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALR----NRRLLRKVIKAAALEEHNAAMK 737
            S    E++ LR QL     Q+ +   ++   + +     R L  + +K   L+E+ + + 
Sbjct: 773  SEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVS 832

Query: 738  DQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQ 797
               +  EK++Q+ K    +       +Q      V KLH +        E+F   S +L+
Sbjct: 833  QVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQK-------EEQFNMLSSDLE 885

Query: 798  TKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGE 857
               E+  +M A+ R + ++    +   E L + +++ +  S     Q+  +N +L     
Sbjct: 886  KLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL----R 941

Query: 858  VNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLA 917
            + E  +E+LQ K +   +    ++ +      K      +  ++ +  +K +    S L 
Sbjct: 942  LKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE 1001

Query: 918  KKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRL-----EKD 972
            KK      +  + +  +L+AR +   +E++ + ++ I Q  +  +LD   +L     E  
Sbjct: 1002 KK-----METSHNQCQELKARYERATSETKTKHEE-ILQNLQKTLLDTEDKLKGAREENS 1055

Query: 973  GLLKKLEE-----EKAEAAEAAEERL 993
            GLL++LEE     +KA+AA+ AE+ +
Sbjct: 1056 GLLQELEELRKQADKAKAAQTAEDAM 1081



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 65/318 (20%), Positives = 139/318 (43%), Gaps = 24/318 (7%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAA----MKDQL 740
            S ++  LR+ L  +  +   +  + +Q      +L   + +   +   N++    M D+L
Sbjct: 881  SSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 940

Query: 741  KLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQ----IRQLQHDREEFYNQSQEL 796
            +L+E+D++  ++ L K     + LQ+  + M  K         ++ + +++E   +  +L
Sbjct: 941  RLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDL 1000

Query: 797  QTKLEDCRNMIAELRIELKKANN--KVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLV 854
            + K+E   N   EL+   ++A +  K  H E+L +     L   + ++   E       +
Sbjct: 1001 EKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGARE---ENSGL 1057

Query: 855  LGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKE-------LEKNRSHVLQQTQRLDTSQK 907
            L E+ EL  +  + K + T ++   +     KE       LE  +    +    LDT ++
Sbjct: 1058 LQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKE 1117

Query: 908  RILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYG 967
              L+    L K   LL  + + +E+ + +     QAA  + + Q    Q   +++ +  G
Sbjct: 1118 NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQ-QLSALQEENVKLAEELG 1176

Query: 968  RLEKDGLL--KKLEEEKA 983
            R  +D +   +KLEEE++
Sbjct: 1177 R-SRDEVTSHQKLEEERS 1193



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 63/319 (19%), Positives = 130/319 (40%), Gaps = 44/319 (13%)

Query: 711  QHALRNRRLLRKVIKAAALEEHNAAMKDQLK-LQEKDIQMWKVSLQKEQARYNQLQEQRD 769
            QH + N +  +   +AA  +E  A     +K ++EK+  +  +  + ++A    L E  D
Sbjct: 660  QHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMED 719

Query: 770  TMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLS 829
            T+     ++I+           + + LQ K  +   +I     +LK    K+   + L  
Sbjct: 720  TLNKLQEAEIK---------VKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRK 770

Query: 830  QVSQKLSNSESVQQQMEFLNRQLLVLG-----------------EVNELYLEQLQNKHSD 872
              S+  S  + ++QQ+E   +Q+  L                  +  EL L  LQ    +
Sbjct: 771  ASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQ----E 826

Query: 873  TTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHL-------LLE 925
               EV  +K    KEL+  +    + ++   + Q+ + E  + L +K+         L +
Sbjct: 827  NLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEK 886

Query: 926  QKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEE---K 982
             ++ L D++ + R + +  E   +A++++      EI+ + G  +    L K+ +E   K
Sbjct: 887  LRENLADMEAKFREKDEREEQLIKAKEKLENDI-AEIMKMSG--DNSSQLTKMNDELRLK 943

Query: 983  AEAAEAAEERLDCCNDGCS 1001
                E  + +L   N+  S
Sbjct: 944  ERDVEELQLKLTKANENAS 962



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 82/391 (20%), Positives = 150/391 (38%), Gaps = 83/391 (21%)

Query: 639  GVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLL 698
            G PST+P +     +++     S  L + P  S     +    S  S   RT        
Sbjct: 282  GFPSTTPAKAKANAVRRVMATTSASLKRSPSASSLSSMSSVASSVSSRPSRT-------- 333

Query: 699  HNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQ 758
               LL E          + R  RK+    AL+E                     +L+++Q
Sbjct: 334  --GLLTET---------SSRYARKISGTTALQE---------------------ALKEKQ 361

Query: 759  ARYNQLQEQRD---TMVTKLHSQIRQLQHD----REEFYNQSQELQTKLEDCRNMIAELR 811
                QL  +RD     V K  S + +++ +    R+       EL+ K++  R M+    
Sbjct: 362  QHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD 421

Query: 812  IELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVN-ELYLEQLQNKH 870
             E  +          LL+Q+ ++    E +Q ++E    + +  G++  +  LE  + K 
Sbjct: 422  REKVE----------LLNQLEEEKRKVEDLQFRVE---EESITKGDLETQTKLEHARIKE 468

Query: 871  SDTTKEVEMMKA-AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKY 929
             + +   E  KA   ++ELE  R   + +       + RI+ELE  LA +   + E ++ 
Sbjct: 469  LEQSLLFEKTKADKLQRELEDTRVATVSE-------KSRIMELEKDLALRVQEVAELRRR 521

Query: 930  LE--------DVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEE 981
            LE        D+ L    ++ + + + E  +   Q    EI  L    E  G  ++  ++
Sbjct: 522  LESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQ---REITSL---KEHFGAREETHQK 575

Query: 982  KAEAAEAAEERLDCCNDGCSDSMVGHNEEAS 1012
            + +A   A E+L   N+     +   N+E S
Sbjct: 576  EIKALYTATEKLSKENESLKSKLEHANKENS 606


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 105/469 (22%), Positives = 199/469 (42%), Gaps = 46/469 (9%)

Query: 622  RKTEELLKKAKGNTEEDGVPSTSPME-VLDRLIQQGADAHSKELNKLPLPSKSVDWTHFG 680
            R  EE L+ AK   E       + ME ++      G + H  E +K  L  + V+     
Sbjct: 1490 RALEEALE-AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL-EQQVEEMRTQ 1547

Query: 681  GSPPSDEIRTLRDQLLLL--HNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKD 738
                 DE++   D  L L  + Q +  +F+R       +   +K +    + E  A ++D
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED 1607

Query: 739  QLKLQEKDIQMWK---VSLQKEQARYNQLQEQRDTMVT---KLHSQIRQLQHD------- 785
            + K +   +   K   + L+  +A+     + RD ++    KL +Q++  Q +       
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARAS 1667

Query: 786  REEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES----- 840
            R+E + QS+E + KL+     I +L+ EL  +     H E    +++ +++NS S     
Sbjct: 1668 RDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSAL 1727

Query: 841  --VQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKA--AYRKELEKNRSHVL 896
               ++++E    QL    E  +  +E L ++   TT +V+ + A  A  +   +   +  
Sbjct: 1728 LDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNAR 1787

Query: 897  QQTQRLDTSQK-RILELESHLAKKDHL---LLEQK--KYLEDVKLQARGQLQAAESRYEA 950
            QQ +R +   K ++ ELE  +  K       LE K  +  E ++ +A+ +  A +     
Sbjct: 1788 QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1847

Query: 951  QKRITQVF-----ELEILDLY-GRLEK-DGLLKKLE------EEKAEAAEAAEERLDCCN 997
            +K++ ++F     E    D Y  ++EK +  +K+L+      EE+A  A A+  +L    
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907

Query: 998  DGCSDSMVGHNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELS 1046
            D  +++  G + E S      +   P S   S   R       +S ELS
Sbjct: 1908 DDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELS 1956



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 67/339 (19%), Positives = 146/339 (43%), Gaps = 42/339 (12%)

Query: 692  RDQLLLLHNQLLYERFKRQQHALRNRRLLRKVI--KAAALEEHNAAMKDQLKLQEKDIQM 749
            + Q LL    +L E+ + +         +R  +  K   LEE    ++ +++ +E+  Q+
Sbjct: 881  KHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQI 940

Query: 750  WKVSLQKEQARYNQLQEQRD-----------------TMVTKLHSQIRQLQHDREEFYNQ 792
             +   +K QA    L+EQ D                   + K+  +I  L+    +F  +
Sbjct: 941  LQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE 1000

Query: 793  SQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQL 852
             + ++ ++ +C + +AE   + K         E+++S + ++L   E  +Q++E   R+L
Sbjct: 1001 KKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKL 1060

Query: 853  LVLGEVNEL--YLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRIL 910
               GE  +L   + +LQ +      E+++  A   +EL+   +    +T   + + K + 
Sbjct: 1061 --DGETTDLQDQIAELQAQ----IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVR 1114

Query: 911  ELESHLAKKDHLLLEQKKYLEDVKLQARG---QLQAAESRYE-------AQKRITQVFEL 960
            EL++ +A+       +K      + Q R    +L+A ++  E       AQ+ +    E 
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174

Query: 961  EILDLYGRLEK-----DGLLKKLEEEKAEAAEAAEERLD 994
            E+ +L   LE+     +  ++ + +  A A E   E+L+
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE 1213



 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 74/340 (21%), Positives = 145/340 (42%), Gaps = 41/340 (12%)

Query: 687  EIRTLRDQLLLLHNQLLYERFK---------RQQHALRNRRLLRKVIKAAALEEHNAAMK 737
            E+RT R+Q +    + L E  K         RQ+HA     L  ++ +A   + +    K
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226

Query: 738  DQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQ 797
              L+   K++      LQ+ +A     +++ D  V +LH+++ +    R E   ++ +LQ
Sbjct: 1227 QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ 1286

Query: 798  TKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGE 857
             +L++   ++ E   +  K        E  L    + L   E  +Q++   +R   +  E
Sbjct: 1287 NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL--QEETRQKLNLSSRIRQLEEE 1344

Query: 858  VNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHV---LQQTQRLDTSQKRILELES 914
             N   L++ Q +  +  K +E    A + +L   +  V   L   + L+ ++K++L+   
Sbjct: 1345 KNS--LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAE 1402

Query: 915  HLAKKDHLLLEQK---------------KYLEDVKLQARGQLQAAESRYEAQKRITQVF- 958
             L+++    LE+K               + L+D+ +    Q Q A +  + QK+  Q+  
Sbjct: 1403 ALSQR----LEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLA 1458

Query: 959  -ELEILDLYGRLEKDGLLKKLEEEKAEA---AEAAEERLD 994
             E  I   Y   E+D    +  E++ +A   A A EE L+
Sbjct: 1459 EEKSISARYAE-ERDRAEAEAREKETKALSLARALEEALE 1497



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 72/332 (21%), Positives = 146/332 (43%), Gaps = 39/332 (11%)

Query: 686  DEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAA----LEEHNAAMKDQLK 741
            +E + ++  +  L  QL  E   RQ+  L       K+ K       LE+ N+    + K
Sbjct: 943  NEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002

Query: 742  LQEKDIQMWKVSLQKEQARYNQL---QEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQT 798
            L E  I      L +E+ +   L   + +++ M++ L  ++++ +  R+E     ++L  
Sbjct: 1003 LMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG 1062

Query: 799  KLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEV 858
            +  D ++ IAEL+ ++ +   ++   E  L Q +    + E++ +     N  L V+ E 
Sbjct: 1063 ETTDLQDQIAELQAQIDELKLQLAKKEEEL-QGALARGDDETLHK-----NNALKVVRE- 1115

Query: 859  NELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILEL----ES 914
                   LQ + ++  ++ E  KA+ R + EK +  + ++ + L T  +  L+     + 
Sbjct: 1116 -------LQAQIAELQEDFESEKAS-RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQE 1167

Query: 915  HLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRY-----EAQKRITQV--FELEILDLYG 967
               K++  + E KK LE+       Q+Q    R+     E  +++ Q   F+  +     
Sbjct: 1168 LRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQ 1227

Query: 968  RLEKDGL-----LKKLEEEKAEAAEAAEERLD 994
             LE D       +K L++ KAE +E   ++LD
Sbjct: 1228 GLETDNKELACEVKVLQQVKAE-SEHKRKKLD 1258



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 81/399 (20%), Positives = 161/399 (40%), Gaps = 59/399 (14%)

Query: 637  EDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLL 696
            +D + +   +E   + + + A+A S+ L +  L    ++ T        D++    D   
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD--- 1437

Query: 697  LLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQK 756
              H + +    +++Q          K I A   EE + A   + + +EK+ +   ++   
Sbjct: 1438 --HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA---EAEAREKETKALSLARAL 1492

Query: 757  EQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKK 816
            E+A   + +E+ +    +L + +  L   +++      EL+         + E+R +L++
Sbjct: 1493 EEAL--EAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550

Query: 817  ANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNE----LYLEQLQNKHSD 872
              +++  TE        KL    ++Q       R L    E NE    L ++Q++   ++
Sbjct: 1551 LEDELQATE------DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAE 1604

Query: 873  TTKEVEM--MKAAYRKELE--------------KNRSHVLQQTQRLDTSQKRI-LELESH 915
               E +   +  A +K++E              K R  V++Q ++L    K    ELE  
Sbjct: 1605 LEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEA 1664

Query: 916  LAKKDHLLLEQK------KYLEDVKLQARGQLQAAE--SRYEAQKRITQVFEL------- 960
             A +D +  + K      K LE   LQ + +L ++E   R+  Q+R     E+       
Sbjct: 1665 RASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGK 1724

Query: 961  -EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCND 998
              +LD   RLE    + +LEEE     E  +  ++  ND
Sbjct: 1725 SALLDEKRRLE--ARIAQLEEE----LEEEQSNMELLND 1757


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
            [Homo sapiens]
          Length = 918

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 73/347 (21%), Positives = 152/347 (43%), Gaps = 24/347 (6%)

Query: 683  PPSDEIRTLRDQL-LLLHNQLLYERFKRQQHALRN----RRLLRKVIKAAALEEHNAAMK 737
            P S  +R LR  L  +  NQ+L       +  +++       LR   K + +E+    ++
Sbjct: 484  PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLE 543

Query: 738  DQLKLQEKD-IQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQEL 796
            +  + +E + ++  KV   K + R  +++ +R+  + K+     +++  +EE   Q ++ 
Sbjct: 544  NLRRKEEAEQLRRQKVEEDKRR-RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQK 602

Query: 797  QTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLG 856
              ++++      E R+  +KA  K           ++K+   E+ ++Q E   R   +  
Sbjct: 603  FAQIDEKTEKAKEERLAEEKAKKKAA---------AKKMEEVEARRKQEEEARRLRWLQQ 653

Query: 857  EVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHL 916
            E  E   ++L  K  +  +E  + KAA  K L + R    ++ +R +  ++     E   
Sbjct: 654  EEEERRHQELLQKKKEEEQE-RLRKAAEAKRLAEQREQERREQERREQERREQERREQER 712

Query: 917  AKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGL-- 974
             +++  L EQ++  E  +LQA  +LQ  E     QK   +  + E+ +   + E+  L  
Sbjct: 713  REQERQLAEQERRREQERLQAERELQEREKALRLQK---EQLQRELEEKKKKEEQQRLAE 769

Query: 975  --LKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETK 1019
              L++ +E+KA+ A  A + L+   D  S +   +     GH    K
Sbjct: 770  RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPK 816


>gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]
          Length = 625

 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 88/390 (22%), Positives = 163/390 (41%), Gaps = 49/390 (12%)

Query: 620 VIRKTEELLKKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHF 679
           V+    E+L+    + EED     S +     + +   + + KE  K    S+       
Sbjct: 70  VLLSENEMLQAKLHSQEEDFRLQNSTL-----MAEFSKERYGKEAGKFSAVSEGQ----- 119

Query: 680 GGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQ 739
            G PP     T+   + L   +L +E  K ++  L  +    + ++++   E +   ++ 
Sbjct: 120 -GDPPGGPAPTVLAPMPLAEVELKWEMEKEEKRLLWEQL---QGLESSKQAETSRLQEEL 175

Query: 740 LKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYN----QSQE 795
            KL EK        L+K+Q  + +LQ +++T+     ++I +LQ  +E  +     ++Q+
Sbjct: 176 AKLSEK--------LKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQK 227

Query: 796 LQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQME-------FL 848
           LQ +LE     +AELR +  +   ++ H   L +   Q    S   Q+Q+E        L
Sbjct: 228 LQQELEAANQSLAELRDQ--RQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNAL 285

Query: 849 NRQLLVLGEVNELYLEQLQNKHSDTT---KEVEMMKAAYRKELEKNRSHVLQQTQRLDTS 905
              L  L ++     ++L      TT    E++  +A Y ++L   +  +  Q Q    +
Sbjct: 286 RTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEY-EDLMGQKDDLNSQLQESLRA 344

Query: 906 QKRILE-LESHLAKKDHL---LLEQKKYLEDVKLQ----ARGQLQAAESRYEAQKRITQV 957
             R+LE L+    +K+ L   L E +K  E  K      A   LQ      E    +   
Sbjct: 345 NSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLR 404

Query: 958 FELEILDLYGRLEKDGLLKKLEEEKAEAAE 987
            E E+L +  R E++  L++L E+K    E
Sbjct: 405 HEKEVLGVRARYERE--LRELHEDKKRQEE 432



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 76/322 (23%), Positives = 134/322 (41%), Gaps = 41/322 (12%)

Query: 688 IRTLRDQLLL--LHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEK 745
           +R L+DQ+ +     Q   E    + +ALR           AALE+   A   +L +  +
Sbjct: 257 LRALQDQVSIQSADAQEQVEGLLAENNALRT--------SLAALEQIQTAKTQELNMLRE 308

Query: 746 DIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRN 805
                   LQ++QA Y  L  Q+D     L+SQ+++          Q QE+  + E    
Sbjct: 309 QTTGLAAELQQQQAEYEDLMGQKD----DLNSQLQESLRANSRLLEQLQEIGQEKEQLTQ 364

Query: 806 MIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQ 865
            + E R   +K   K    EL +  + +K  + E +      L  +  VLG V   Y  +
Sbjct: 365 ELQEARKSAEK--RKAMLDELAMETLQEKSQHKEELGAVR--LRHEKEVLG-VRARYERE 419

Query: 866 LQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKD----- 920
           L+  H D  ++ E ++   R+E  +        T+ L+T Q+ + EL++ +   D     
Sbjct: 420 LRELHEDKKRQEEELRGQIREEKAR--------TRELETLQQTVEELQAQVHSMDGAKGW 471

Query: 921 -HLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGR---LEKDG--L 974
               L++ +  E+     R QL+ A+   +   +     + E+ D       LEK G   
Sbjct: 472 FERRLKEAEGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAA 531

Query: 975 LKKLEEE---KAEAAEAAEERL 993
           LK L+ +   + + A+  +ERL
Sbjct: 532 LKDLKRQLHLERKRADKLQERL 553


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
            [Homo sapiens]
          Length = 914

 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 70/343 (20%), Positives = 149/343 (43%), Gaps = 20/343 (5%)

Query: 683  PPSDEIRTLRDQL-LLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK 741
            P S  +R LR  L  +  NQ+L       +  +++       ++    E+    +++  +
Sbjct: 484  PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR 543

Query: 742  LQEKD-IQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKL 800
             +E + ++  KV   K + R  +++ +R+  + K+     +++  +EE   Q ++   ++
Sbjct: 544  KEEAEQLRRQKVEEDKRR-RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQI 602

Query: 801  EDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNE 860
            ++      E R+  +KA  K           ++K+   E+ ++Q E   R   +  E  E
Sbjct: 603  DEKTEKAKEERLAEEKAKKKAA---------AKKMEEVEARRKQEEEARRLRWLQQEEEE 653

Query: 861  LYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKD 920
               ++L  K  +  +E  + KAA  K L + R    ++ +R +  ++     E    +++
Sbjct: 654  RRHQELLQKKKEEEQE-RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 712

Query: 921  HLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGL----LK 976
              L EQ++  E  +LQA  +LQ  E     QK   +  + E+ +   + E+  L    L+
Sbjct: 713  RQLAEQERRREQERLQAERELQEREKALRLQK---EQLQRELEEKKKKEEQQRLAERQLQ 769

Query: 977  KLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETK 1019
            + +E+KA+ A  A + L+   D  S +   +     GH    K
Sbjct: 770  EEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPK 812


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sapiens]
          Length = 693

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 73/345 (21%), Positives = 155/345 (44%), Gaps = 38/345 (11%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQL 764
            +R    + A+  RRL + + + A L  H   + + LK  + +   +   ++ E+AR+ + 
Sbjct: 187  DRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE- 245

Query: 765  QEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAE--------LRIELKK 816
                   + K+  + R L+ +++   ++ QEL+  L + +N +AE        +   +++
Sbjct: 246  ------RMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQ 299

Query: 817  ANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNR-QLLVLGEVNELYLEQLQNKHSDTTK 875
              ++  H    +  +  KL +     Q +  L++ Q   L E  E+  EQ   +  +  +
Sbjct: 300  LQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQER 359

Query: 876  EVEMMKAA--YRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL--E 931
              E  +     +K L++    + +Q QRL   ++R+ + E  L K++  L +Q++ L  +
Sbjct: 360  LCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKK 419

Query: 932  DVKLQARGQLQAAESRYEAQKRITQVFELEILDLYG------RLEKD--GLLKKLEEEKA 983
            + +LQ + +  A    ++  K++ +  +    DL        +LE+    L +KL+EE  
Sbjct: 420  EERLQKQEERLALSQNHKLDKQLAEP-QCSFEDLNNEKKSALQLEQQVKELQEKLDEEHL 478

Query: 984  EAAEAAEERLDCCNDGCSDSMVGHNEEASG----HNGETKTPRPS 1024
            EAA    ++L+        S+V    E  G     + E + PRP+
Sbjct: 479  EAASQRNQQLE-----TQLSLVALPGEGDGGQHLDSEEEEAPRPT 518



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 56/262 (21%), Positives = 105/262 (40%), Gaps = 33/262 (12%)

Query: 731 EHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFY 790
           E+N A+    K Q++ +Q  +  L++++A+  + QE+      +L  Q + LQ   E   
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR 382

Query: 791 NQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNR 850
            Q Q L+ + E            L+K   ++   E  L    ++L   E   Q+ E    
Sbjct: 383 KQEQRLRKQEE-----------RLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE---- 427

Query: 851 QLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRIL 910
           + L L + ++L             K++   + ++ ++L   +   LQ  Q++   Q+++ 
Sbjct: 428 ERLALSQNHKL------------DKQLAEPQCSF-EDLNNEKKSALQLEQQVKELQEKLD 474

Query: 911 ELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLE 970
           E     A + +  LE +  L  +  +  G         EA +    + E    DL  R E
Sbjct: 475 EEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPE----DLESR-E 529

Query: 971 KDGLLKKLEEEKAEAAEAAEER 992
                  L +EKA+  E  E R
Sbjct: 530 ATSSFMDLPKEKADGTEQVERR 551



 Score = 35.4 bits (80), Expect = 0.32
 Identities = 62/309 (20%), Positives = 132/309 (42%), Gaps = 42/309 (13%)

Query: 686 DEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQ---LKL 742
           ++ + L++Q  +L  Q   +R + Q+        LR+  K   L+E    ++ Q   L+ 
Sbjct: 334 EQKQRLQEQEEMLREQEA-QRVREQERLCEQNERLREQQKT--LQEQGERLRKQEQRLRK 390

Query: 743 QEKDIQMWKVSLQKEQARY-----------NQLQEQRDTMVT----KLHSQIRQLQHDRE 787
           QE+ ++  +  LQK++ R             +LQ+Q + +      KL  Q+ + Q   E
Sbjct: 391 QEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFE 450

Query: 788 EFYNQSQ---ELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQ 844
           +  N+ +   +L+ ++++ +  + E  +E     N+   T+L L  +  +    + +  +
Sbjct: 451 DLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSE 510

Query: 845 MEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDT 904
            E   R    + E  +L   +  +   D  KE    KA   +++E+     +Q +   D 
Sbjct: 511 EEEAPRPTPNIPE--DLESREATSSFMDLPKE----KADGTEQVERRELGFVQPSGVTDG 564

Query: 905 SQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILD 964
            ++     ES  A  +     + + +EDV       ++ A+   E + ++ ++ EL +L 
Sbjct: 565 MRESFTVYESQGAVPN----TRHQEMEDV-------IRLAQKEEEMKVKLLELQEL-VLP 612

Query: 965 LYGRLEKDG 973
           L G  E  G
Sbjct: 613 LVGNHEGHG 621


>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
            isoform 1 [Homo sapiens]
          Length = 693

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 73/345 (21%), Positives = 155/345 (44%), Gaps = 38/345 (11%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQL 764
            +R    + A+  RRL + + + A L  H   + + LK  + +   +   ++ E+AR+ + 
Sbjct: 187  DRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE- 245

Query: 765  QEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAE--------LRIELKK 816
                   + K+  + R L+ +++   ++ QEL+  L + +N +AE        +   +++
Sbjct: 246  ------RMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQ 299

Query: 817  ANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNR-QLLVLGEVNELYLEQLQNKHSDTTK 875
              ++  H    +  +  KL +     Q +  L++ Q   L E  E+  EQ   +  +  +
Sbjct: 300  LQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQER 359

Query: 876  EVEMMKAA--YRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL--E 931
              E  +     +K L++    + +Q QRL   ++R+ + E  L K++  L +Q++ L  +
Sbjct: 360  LCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKK 419

Query: 932  DVKLQARGQLQAAESRYEAQKRITQVFELEILDLYG------RLEKD--GLLKKLEEEKA 983
            + +LQ + +  A    ++  K++ +  +    DL        +LE+    L +KL+EE  
Sbjct: 420  EERLQKQEERLALSQNHKLDKQLAEP-QCSFEDLNNEKKSALQLEQQVKELQEKLDEEHL 478

Query: 984  EAAEAAEERLDCCNDGCSDSMVGHNEEASG----HNGETKTPRPS 1024
            EAA    ++L+        S+V    E  G     + E + PRP+
Sbjct: 479  EAASQRNQQLE-----TQLSLVALPGEGDGGQHLDSEEEEAPRPT 518



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 56/262 (21%), Positives = 105/262 (40%), Gaps = 33/262 (12%)

Query: 731 EHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFY 790
           E+N A+    K Q++ +Q  +  L++++A+  + QE+      +L  Q + LQ   E   
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR 382

Query: 791 NQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNR 850
            Q Q L+ + E            L+K   ++   E  L    ++L   E   Q+ E    
Sbjct: 383 KQEQRLRKQEE-----------RLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE---- 427

Query: 851 QLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRIL 910
           + L L + ++L             K++   + ++ ++L   +   LQ  Q++   Q+++ 
Sbjct: 428 ERLALSQNHKL------------DKQLAEPQCSF-EDLNNEKKSALQLEQQVKELQEKLD 474

Query: 911 ELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLE 970
           E     A + +  LE +  L  +  +  G         EA +    + E    DL  R E
Sbjct: 475 EEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPE----DLESR-E 529

Query: 971 KDGLLKKLEEEKAEAAEAAEER 992
                  L +EKA+  E  E R
Sbjct: 530 ATSSFMDLPKEKADGTEQVERR 551



 Score = 35.4 bits (80), Expect = 0.32
 Identities = 62/309 (20%), Positives = 132/309 (42%), Gaps = 42/309 (13%)

Query: 686 DEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQ---LKL 742
           ++ + L++Q  +L  Q   +R + Q+        LR+  K   L+E    ++ Q   L+ 
Sbjct: 334 EQKQRLQEQEEMLREQEA-QRVREQERLCEQNERLREQQKT--LQEQGERLRKQEQRLRK 390

Query: 743 QEKDIQMWKVSLQKEQARY-----------NQLQEQRDTMVT----KLHSQIRQLQHDRE 787
           QE+ ++  +  LQK++ R             +LQ+Q + +      KL  Q+ + Q   E
Sbjct: 391 QEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFE 450

Query: 788 EFYNQSQ---ELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQ 844
           +  N+ +   +L+ ++++ +  + E  +E     N+   T+L L  +  +    + +  +
Sbjct: 451 DLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSE 510

Query: 845 MEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDT 904
            E   R    + E  +L   +  +   D  KE    KA   +++E+     +Q +   D 
Sbjct: 511 EEEAPRPTPNIPE--DLESREATSSFMDLPKE----KADGTEQVERRELGFVQPSGVTDG 564

Query: 905 SQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILD 964
            ++     ES  A  +     + + +EDV       ++ A+   E + ++ ++ EL +L 
Sbjct: 565 MRESFTVYESQGAVPN----TRHQEMEDV-------IRLAQKEEEMKVKLLELQEL-VLP 612

Query: 965 LYGRLEKDG 973
           L G  E  G
Sbjct: 613 LVGNHEGHG 621


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
          Length = 570

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 84/428 (19%), Positives = 185/428 (43%), Gaps = 50/428 (11%)

Query: 602  PPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTE-EDGVPSTSPMEVLDRLIQQGADAH 660
            P + HL     P    H ++ K     K A+   +  D  P T+P      +    +D  
Sbjct: 22   PTHPHL--PTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPS-----VGTAASDTK 74

Query: 661  SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 720
             K++N    P  +   T  G   P DE +         H + L    + Q   +R     
Sbjct: 75   KKKINNGTNPETT---TSGGCHSPEDEQKASHQ-----HQEALRRELEAQVQTIRILTCQ 126

Query: 721  RKVIKAAALEEHNAAMKDQLKLQEKDI-----QMWKVSLQKEQA------------RY-N 762
            +  ++ A     +A    QL+ + +D+       WK + + EQA            RY  
Sbjct: 127  KTELQMALYYSQHAVK--QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIE 184

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            +L ++RD +  +L+   R    D EE   ++ +LQ KL+   +  +E+++ +K+   K+ 
Sbjct: 185  ELTKERDALSLELY---RNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 240

Query: 823  HTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKA 882
              +LLL Q  Q  + ++ + ++++ ++ +L    E NEL+    Q +     ++ E ++ 
Sbjct: 241  RAKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 299

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQ 942
               K +++    + +Q +++   ++ + E E  + +++ ++ E+++ + +++ +   Q +
Sbjct: 300  REEK-IQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 358

Query: 943  AAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSD 1002
              E   + Q+      E +I +   R E++  + + EE+  E  E   E+ +   +   +
Sbjct: 359  IREQEEKRQE------EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE--QE 410

Query: 1003 SMVGHNEE 1010
              +G  EE
Sbjct: 411  EKMGEQEE 418



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 49/256 (19%), Positives = 121/256 (47%), Gaps = 20/256 (7%)

Query: 743 QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
           Q+++ +MW+   +K Q R  ++QEQ +    K+  Q  +++   E  + + ++++ + E 
Sbjct: 284 QQQEEKMWRQE-EKIQEREEKIQEQEE----KIREQEEKMRRQEEMMWEKEEKMRRQEE- 337

Query: 803 CRNMIAELRIELKKANNKVCHTELLLSQVS-----QKLSNSESVQQQMEFLNRQLLVLGE 857
              M+ E   ++++   K+   E +  Q       +K+   E  Q+Q   + RQ   + E
Sbjct: 338 ---MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 394

Query: 858 VNELYLEQ--LQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESH 915
             E   EQ  +  +  +   E E       +E+++    + +Q +++   +K+I E E  
Sbjct: 395 QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454

Query: 916 LAKKDHLLLEQKKYL---EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRL-EK 971
           + +++ ++ EQ++ +   E    +   ++Q  E +   Q+   +  E +I +   ++ E+
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514

Query: 972 DGLLKKLEEEKAEAAE 987
           + ++++ EE+  E  E
Sbjct: 515 EEMMQEQEEKMWEQEE 530



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 40/242 (16%), Positives = 113/242 (46%), Gaps = 7/242 (2%)

Query: 705 ERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYN 762
           E+ +RQ+  +  +  ++ R+       EE    +++++  QEK  +  +   ++E+ R  
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375

Query: 763 QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
           + +++++  + +   +IR+ +    E     QE + K+ +    + E   E+++   K+ 
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435

Query: 823 HTELLLSQVSQKL-SNSESVQQQMEFLNRQLLVLGEVNELYLEQ---LQNKHSDTTKEVE 878
             E  + +  +K+    E +++Q E +  Q   +GE      EQ   +Q +     ++ E
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495

Query: 879 MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQAR 938
            ++    K++ +    + +Q + +   ++++ E E  + +++  + EQ++ +   + + R
Sbjct: 496 KIR-EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554

Query: 939 GQ 940
            Q
Sbjct: 555 EQ 556



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 48/273 (17%), Positives = 119/273 (43%), Gaps = 25/273 (9%)

Query: 700 NQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQA 759
           NQ   E+  RQ+  ++ R       K    EE     +++++ QE+ +   +  +++++ 
Sbjct: 283 NQQQEEKMWRQEEKIQEREE-----KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 337

Query: 760 RYNQLQEQRDTMVTKLHSQ--IRQLQHDREE-----FYNQSQELQTKLEDCRNMIAELRI 812
              + +E+   +  K+H Q  IR+ +  R+E        + QE + K+      I E   
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397

Query: 813 ELKKANNKVCHTELLLSQVSQKL-SNSESVQQQMEFLNRQLLVLGEVNELYLEQ------ 865
           ++++    +   E  + +  +K+    E +Q+Q E + RQ   + E  +   EQ      
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457

Query: 866 ---LQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHL 922
              +  +  +   E E        ++++    + +Q +++   +K+I E E  + +++ +
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517

Query: 923 LLEQKKYL---EDVKLQARGQLQAAESRYEAQK 952
           + EQ++ +   E+   +   ++Q  E +   Q+
Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 550


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 86/424 (20%), Positives = 184/424 (43%), Gaps = 55/424 (12%)

Query: 602 PPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTE-EDGVPSTSPMEVLDRLIQQGADAH 660
           P + HL     P    H ++ K     K A+   +  D  P T+P      +    +D  
Sbjct: 34  PTHPHL--PTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPS-----VGTAASDTK 86

Query: 661 SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 720
            K++N    P  +   T  G   P DE +         H + L    + Q H +R     
Sbjct: 87  KKKINNGTNPETT---TSGGCHSPEDEQKASHQ-----HQEALRRELEAQVHTIRILTCQ 138

Query: 721 RKVIKAAALEEHNAAMKDQLKLQEKDI-----QMWKVSLQKEQA------------RY-N 762
           +  ++ A     +A    QL+ + +D+       WK + + EQA            RY  
Sbjct: 139 KTELQMALYYSQHAVK--QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIE 196

Query: 763 QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
           +L ++RD +  +L+   R    D EE   ++ +LQ KL+   +  +E+++ +K+   K+ 
Sbjct: 197 ELTKERDALSLELY---RNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 252

Query: 823 HTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY--LEQLQN----KHSDTTKE 876
             +LLL Q  Q  + ++ + ++++ ++ +L    E NEL+  L Q Q     +  +  +E
Sbjct: 253 RAKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311

Query: 877 VEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQK---KYLEDV 933
            E       +++ +    + +Q +++   ++ + E E  + +++ ++ E++   + LE++
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 371

Query: 934 KLQARGQLQAAESRYEAQKRITQVFEL-----EILDLYGRLEKDGLLKKLEEEKAEAAEA 988
             +   +++  E +   Q++I +  E      +I +   R E++  + + EE+  E  E 
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431

Query: 989 AEER 992
             E+
Sbjct: 432 IREQ 435



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 35/222 (15%), Positives = 99/222 (44%), Gaps = 39/222 (17%)

Query: 733 NAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQ 792
           N   ++++  QE+ IQ W+  +Q+++ +  + +E       K+  Q  +++   E  + +
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE-------KIREQEEKMRRQEEMMWEK 347

Query: 793 SQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQL 852
            ++++ + E    M+ E   ++++    +   E  + ++ +K+   E +++Q E      
Sbjct: 348 EEKMRRQEE----MMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE------ 397

Query: 853 LVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILEL 912
                                 K  E  K   +++ ++  + + +Q +++   +++I E 
Sbjct: 398 ----------------------KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435

Query: 913 ESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRI 954
           E  + +++  + EQ+K  E+ K Q + ++   E +   Q+ I
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 42/233 (18%), Positives = 108/233 (46%), Gaps = 18/233 (7%)

Query: 709 RQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQK-EQARYNQLQEQ 767
           RQ+  +  +  +R+  K    EE     + + K++E++ ++W+   +  EQ +  + +E+
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEE---MWRQEEKIREQE-EIWRQKEKMHEQEKIRKQEEK 496

Query: 768 RDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELL 827
                 K+H Q  +++   E+ + Q ++++ + E  R    E   ++++    +   E  
Sbjct: 497 VWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR----EQEEKIREQEEMMQEQEEK 552

Query: 828 LSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQ---LQNKHSDTTKEVEMMKAAY 884
           + +  +K+   E +++Q E +  Q   + E  E   EQ   +  +     ++ EMM+   
Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612

Query: 885 RKELE------KNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLE 931
            K  E      +    + +Q +++   ++++ E E  L +++  + E +++LE
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 38/296 (12%), Positives = 132/296 (44%), Gaps = 25/296 (8%)

Query: 705 ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQL 764
           E+ + Q+  +R +    +  +     +     + + K++ ++  MW+   +++  R  ++
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKMRRLEEM 371

Query: 765 QEQRDTMVTKLHSQIRQLQHDREEFYNQSQEL----QTKLEDCRNMIAELRIELKKANNK 820
             +++  + +L  ++ + +  RE+   + +E     Q K ++    +     ++++   K
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431

Query: 821 VCHTELLLSQVSQKLSNSESV-----QQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK 875
           +   E  + +  +K+   E +     +Q+ E + RQ   + E  E++ ++ +    +  +
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491

Query: 876 EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKL 935
           + E       +++      + +Q +++   +++I E E  + +++  + EQ++ +++ + 
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551

Query: 936 QARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEE 991
           +   Q +  + + + +++  ++ E E              +K+ E+K +  E  E+
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQE--------------EKIREQKEKIREQEEK 593



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 27/152 (17%), Positives = 71/152 (46%), Gaps = 6/152 (3%)

Query: 705 ERFKRQQHALRNR--RLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYN 762
           E+   Q+  +R +  ++ R+  K    EE     +++++ QE+ +Q  +  + +++ +  
Sbjct: 502 EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ 561

Query: 763 QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQEL---QTKLEDCRNMIAELRIELKKANN 819
           + QE+      K+  Q  +++  +E+   Q +++   + K+ +   M+ E   ++ +   
Sbjct: 562 E-QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620

Query: 820 KVCHTELLLSQVSQKLSNSESVQQQMEFLNRQ 851
           K+C  E  + +  +K+   E    + E   RQ
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 57/316 (18%), Positives = 147/316 (46%), Gaps = 23/316 (7%)

Query: 686 DEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEK 745
           +E+   +++ +    ++++E+ ++ +          K+ +     +    +++Q K QE+
Sbjct: 416 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 475

Query: 746 DIQMWKVSLQKEQARYNQLQEQRDTM---VTKLHSQIR----QLQHDREEFYNQSQELQT 798
           + +MW+   +K + +  +++EQ + M     K+H Q +    + + ++EE + Q ++++ 
Sbjct: 476 EAKMWRQE-EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 534

Query: 799 KLEDCRNM--IAELRIELKKANNKVCHTELLLSQVSQKL-SNSESVQQQMEFLNRQLLVL 855
           + E  R    I E   +++K   K+   E  +    +K+    E V +Q E +  Q   +
Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI 594

Query: 856 GEVNELYLEQ--LQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELE 913
            E  E   EQ  +  +  +   E E       +++++    + +Q +++   +K+I E E
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654

Query: 914 SHLAKKDHLLLEQKKYL---EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLE 970
             + +++ ++ EQ++ +   E+   +   ++Q  E +   Q+   +++E E+     RL 
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE--KMWEQEV-----RLR 707

Query: 971 KDGLLKKLEEEKAEAA 986
           +     +  +E  EAA
Sbjct: 708 QQEEKMQEHQEHLEAA 723



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 83/410 (20%), Positives = 181/410 (44%), Gaps = 48/410 (11%)

Query: 602 PPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTE-EDGVPSTSPMEVLDRLIQQGADAH 660
           P + HL     P    H ++ K     K A+   +  D  P T+P      +    +D  
Sbjct: 95  PTHPHL--PTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPS-----VGTAASDTK 147

Query: 661 SKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLL 720
            K++N    P  +   T  G   P DE +         H + L    + Q H +R     
Sbjct: 148 KKKINNGTNPETT---TSGGCHSPEDEQKASHQ-----HQEALRRELEAQVHTIRILTCQ 199

Query: 721 RKVIKAAALEEHNAAMKDQLKLQEKDI-----QMWKVSLQKEQA------------RY-N 762
           +  ++ A     +A    QL+ + +D+       WK + + EQA            RY  
Sbjct: 200 KTELQMALYYSQHAVK--QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIE 257

Query: 763 QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
           +L ++RD +  +L+   R    D EE   ++ +LQ KL+   +  +E+++ +K+   K+ 
Sbjct: 258 ELTKERDALSLELY---RNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 313

Query: 823 HTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKA 882
             +LLL Q  Q  + ++ + ++++ ++ +L    E NEL+    Q +     ++ E ++ 
Sbjct: 314 RAKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ- 371

Query: 883 AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQ 942
            + +++++    + +Q +++   ++++   E  + +K+  +  Q++ + + + + R Q  
Sbjct: 372 EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-- 429

Query: 943 AAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEER 992
             E  +E +++I ++ E        R +++   K+ EEEK    E  +E+
Sbjct: 430 -EEMMWEKEEKIRELEEKMHEQEKIREQEE---KRQEEEKIREQEKRQEQ 475



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 35/222 (15%), Positives = 99/222 (44%), Gaps = 39/222 (17%)

Query: 733 NAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQ 792
           N   ++++  QE+ IQ W+  +Q+++ +  + +E       K+  Q  +++   E  + +
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE-------KIREQEEKMRRQEEMMWEK 408

Query: 793 SQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQL 852
            ++++ + E    M+ E   ++++    +   E  + ++ +K+   E +++Q E      
Sbjct: 409 EEKMRRQEE----MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE------ 458

Query: 853 LVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILEL 912
                                 K  E  K   +++ ++  + + +Q +++   +++I E 
Sbjct: 459 ----------------------KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 496

Query: 913 ESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRI 954
           E  + +++  + EQ+K  E+ K Q + ++   E +   Q+ I
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 46/304 (15%), Positives = 137/304 (45%), Gaps = 23/304 (7%)

Query: 705 ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQL 764
           E+ + Q+  +R +    +  +     +     + + K++ ++  MW+   +++  R  ++
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKMRRQEEM 432

Query: 765 QEQRDTMVTKLHSQIRQLQHDREEFYNQSQEL----QTKLEDCRNMIAELRIELKKANNK 820
             +++  + +L  ++ + +  RE+   + +E     Q K ++    +     ++++   K
Sbjct: 433 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492

Query: 821 VCHTELLLSQVSQKLSNSESV-----QQQMEFLNRQLLVLGEVNELY--LEQLQNKHSDT 873
           +   E  + +  +K+   E +     +Q+ E + RQ   + E  E++   E++  +    
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552

Query: 874 TKEVEMMKAAYRK------ELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQK 927
            K+ E M     K      ++ +    V +Q +++   +++I E E  + +++ +  EQ+
Sbjct: 553 RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE 612

Query: 928 KYL---EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRL-EKDGLLKKLEEEKA 983
           + +   E+   +   ++Q  E +   Q+   +  E +I +   ++ E++ ++++ EE+  
Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 672

Query: 984 EAAE 987
           E  E
Sbjct: 673 EQEE 676


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 65/295 (22%), Positives = 134/295 (45%), Gaps = 21/295 (7%)

Query: 711  QHALRNRRLL------RKVIKAAALEEHNAAMKDQLKLQ-EKDIQMWKVSLQKEQARYNQ 763
            Q A R R+L       ++ +    L+E   A+++  +L+ E ++   +  L +EQAR  +
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR--R 2345

Query: 764  LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
            LQE ++ M  +L  + +  Q   E    +  E+  + E  +  +AE+     +A      
Sbjct: 2346 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405

Query: 824  TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-MMKA 882
                  ++ +KL  +E   Q+   L + L +  + ++   E+L+   ++  +E E + + 
Sbjct: 2406 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2465

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA----R 938
            A   +L+      +QQ Q L  +Q      +S L++KD  LL++++++E  K +     +
Sbjct: 2466 AKLLQLKSEEMQTVQQEQLLQETQAL---QQSFLSEKDS-LLQRERFIEQEKAKLEQLFQ 2521

Query: 939  GQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERL 993
             ++  A+   E Q+R  Q  E E   L   +E+    ++ + E  E     +E L
Sbjct: 2522 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEE---ARRRQHEAEEGVRRKQEEL 2573



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 62/307 (20%), Positives = 131/307 (42%), Gaps = 30/307 (9%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK----LQEKDIQMWKVSLQKEQAR 760
            ER +RQ      R+   +V  A+ ++    A +++ +    L+E  +Q  +   +  QA 
Sbjct: 1497 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1556

Query: 761  YNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNK 820
              + ++ +  + T   S   +LQ  R  F  ++ +L+  L++    +A+LR E ++   +
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616

Query: 821  VCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-- 878
                E    +  ++L   +    +   L  Q   + +   L   + + +  +  +E    
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676

Query: 879  --------MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL 930
                      +    +ELEK R       Q+   +++ ++ L +   + +    +Q++ L
Sbjct: 1677 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE----QQRQLL 1732

Query: 931  EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLL---KKLEEEKAEAAE 987
            E+    AR Q +AA +    QKR  Q  E E+  +  R E + LL    + EEE    +E
Sbjct: 1733 EEE--LARLQREAAAA---TQKR--QELEAELAKV--RAEMEVLLASKARAEEESRSTSE 1783

Query: 988  AAEERLD 994
             +++RL+
Sbjct: 1784 KSKQRLE 1790



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/315 (22%), Positives = 131/315 (41%), Gaps = 38/315 (12%)

Query: 711  QHALRNRRLLRKVIKAA-ALEEHNAAMKDQLKLQ-------EKDIQMWKVSLQKEQARYN 762
            +  LR RR + + I A  A  E  AA K +L+L+        +D    K   + E AR  
Sbjct: 1914 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1973

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            QL  + +    +   ++++     EE   Q +    ++E  +  + E R   ++A  +  
Sbjct: 1974 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA 2033

Query: 823  HTELLLSQVSQKLSNSE------SVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK- 875
                L  + +QK   +E      +VQQ+ + L + L    +  +  L+QL+ +     + 
Sbjct: 2034 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL----QQEQSVLDQLRGEAEAARRA 2089

Query: 876  --EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
              E E  +    +E  ++R  V ++ +RL  S +   +  +        L ++ +     
Sbjct: 2090 AEEAEEARVQAEREAAQSRRQV-EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148

Query: 934  KLQARG----QLQAAESRYEAQKRITQV-------FELEILDLYGRLEKDGLLKKLEEE- 981
            + QA      Q QAA++  E  K+  +         E E+  L  +LE+    K L +E 
Sbjct: 2149 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2208

Query: 982  ----KAEAAEAAEER 992
                KAEA EAA +R
Sbjct: 2209 LQRLKAEATEAARQR 2223



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKL 742
            S+E++T++ + LL   Q L + F  ++ +L  R R + ++  K   L +   A   QL+ 
Sbjct: 2473 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR- 2531

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
                        +++Q +  Q++++R  +V  +  + R+ QH+ EE   + QE   +LE 
Sbjct: 2532 ------------EEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQEELQQLEQ 2578

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESV 841
             R    EL  E  +   +    +LL  Q    L++SE V
Sbjct: 2579 QRRQQEELLAEENQRLRE--QLQLLEEQHRAALAHSEEV 2615



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 38/292 (13%)

Query: 706  RFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQ 765
            R ++Q  A R R    + ++   L+ + A    +L+LQ +++   K   Q E  +  +  
Sbjct: 1613 RAQQQAEAERAREEAERELERWQLKANEAL---RLRLQAEEVAQQKSLAQAEAEKQKEEA 1669

Query: 766  EQRDTMVTKLHSQ-IRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHT 824
            E+      K   Q +RQ +   +E   Q Q            +AE   + + A  +    
Sbjct: 1670 EREARRRGKAEEQAVRQRELAEQELEKQRQ------------LAEGTAQQRLAAEQ---- 1713

Query: 825  ELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK---EVEMMK 881
                 ++ +  + +E  +QQ + L  +L  L        ++ Q   ++  K   E+E++ 
Sbjct: 1714 -----ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768

Query: 882  AAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQL 941
            A+  +  E++RS   +  QRL+    R  EL    A+   L  E K+       +   + 
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ------RQLAEE 1822

Query: 942  QAAESRYEAQKRITQVFELEILDLYGRL--EKDGLLKKLEEEKAEAAEAAEE 991
             AA  R EA++ + +  +L  +    RL  E +  LK+ E E       AE+
Sbjct: 1823 DAARQRAEAERVLAE--KLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872



 Score = 33.9 bits (76), Expect = 0.93
 Identities = 49/269 (18%), Positives = 108/269 (40%), Gaps = 52/269 (19%)

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
            ++ +++ W+  + +   R+  +  Q D    +L    RQL++ RE     +  L   L+D
Sbjct: 1170 RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE----SADPLGAWLQD 1225

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
             R    +++                    +  L++S++V++Q+    RQ   L E  E +
Sbjct: 1226 ARRRQEQIQ--------------------AMPLADSQAVREQL----RQEQALLEEIERH 1261

Query: 863  LEQLQ------NKHSDTTKEVEMMKAAYRKELE------------KNRSHVLQQTQRLDT 904
             E+++       ++ +  K+ E+    Y+ +LE                 V+Q+   L T
Sbjct: 1262 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1321

Query: 905  SQKRILELESH----LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
                +  L S     +++    + E+++  E  + + R +L   E+  E Q+++ +    
Sbjct: 1322 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1381

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAA 989
                     E   L ++++EE     EAA
Sbjct: 1382 --AKAQAEREAKELQQRMQEEVVRREEAA 1408


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 65/295 (22%), Positives = 134/295 (45%), Gaps = 21/295 (7%)

Query: 711  QHALRNRRLL------RKVIKAAALEEHNAAMKDQLKLQ-EKDIQMWKVSLQKEQARYNQ 763
            Q A R R+L       ++ +    L+E   A+++  +L+ E ++   +  L +EQAR  +
Sbjct: 2292 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR--R 2349

Query: 764  LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
            LQE ++ M  +L  + +  Q   E    +  E+  + E  +  +AE+     +A      
Sbjct: 2350 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2409

Query: 824  TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-MMKA 882
                  ++ +KL  +E   Q+   L + L +  + ++   E+L+   ++  +E E + + 
Sbjct: 2410 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2469

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA----R 938
            A   +L+      +QQ Q L  +Q      +S L++KD  LL++++++E  K +     +
Sbjct: 2470 AKLLQLKSEEMQTVQQEQLLQETQAL---QQSFLSEKDS-LLQRERFIEQEKAKLEQLFQ 2525

Query: 939  GQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERL 993
             ++  A+   E Q+R  Q  E E   L   +E+    ++ + E  E     +E L
Sbjct: 2526 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEE---ARRRQHEAEEGVRRKQEEL 2577



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 62/307 (20%), Positives = 131/307 (42%), Gaps = 30/307 (9%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK----LQEKDIQMWKVSLQKEQAR 760
            ER +RQ      R+   +V  A+ ++    A +++ +    L+E  +Q  +   +  QA 
Sbjct: 1501 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1560

Query: 761  YNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNK 820
              + ++ +  + T   S   +LQ  R  F  ++ +L+  L++    +A+LR E ++   +
Sbjct: 1561 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620

Query: 821  VCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-- 878
                E    +  ++L   +    +   L  Q   + +   L   + + +  +  +E    
Sbjct: 1621 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1680

Query: 879  --------MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL 930
                      +    +ELEK R       Q+   +++ ++ L +   + +    +Q++ L
Sbjct: 1681 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE----QQRQLL 1736

Query: 931  EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLL---KKLEEEKAEAAE 987
            E+    AR Q +AA +    QKR  Q  E E+  +  R E + LL    + EEE    +E
Sbjct: 1737 EEE--LARLQREAAAA---TQKR--QELEAELAKV--RAEMEVLLASKARAEEESRSTSE 1787

Query: 988  AAEERLD 994
             +++RL+
Sbjct: 1788 KSKQRLE 1794



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/315 (22%), Positives = 131/315 (41%), Gaps = 38/315 (12%)

Query: 711  QHALRNRRLLRKVIKAA-ALEEHNAAMKDQLKLQ-------EKDIQMWKVSLQKEQARYN 762
            +  LR RR + + I A  A  E  AA K +L+L+        +D    K   + E AR  
Sbjct: 1918 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1977

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            QL  + +    +   ++++     EE   Q +    ++E  +  + E R   ++A  +  
Sbjct: 1978 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA 2037

Query: 823  HTELLLSQVSQKLSNSE------SVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK- 875
                L  + +QK   +E      +VQQ+ + L + L    +  +  L+QL+ +     + 
Sbjct: 2038 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL----QQEQSVLDQLRGEAEAARRA 2093

Query: 876  --EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
              E E  +    +E  ++R  V ++ +RL  S +   +  +        L ++ +     
Sbjct: 2094 AEEAEEARVQAEREAAQSRRQV-EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2152

Query: 934  KLQARG----QLQAAESRYEAQKRITQV-------FELEILDLYGRLEKDGLLKKLEEE- 981
            + QA      Q QAA++  E  K+  +         E E+  L  +LE+    K L +E 
Sbjct: 2153 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2212

Query: 982  ----KAEAAEAAEER 992
                KAEA EAA +R
Sbjct: 2213 LQRLKAEATEAARQR 2227



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKL 742
            S+E++T++ + LL   Q L + F  ++ +L  R R + ++  K   L +   A   QL+ 
Sbjct: 2477 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR- 2535

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
                        +++Q +  Q++++R  +V  +  + R+ QH+ EE   + QE   +LE 
Sbjct: 2536 ------------EEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQEELQQLEQ 2582

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESV 841
             R    EL  E  +   +    +LL  Q    L++SE V
Sbjct: 2583 QRRQQEELLAEENQRLRE--QLQLLEEQHRAALAHSEEV 2619



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 38/292 (13%)

Query: 706  RFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQ 765
            R ++Q  A R R    + ++   L+ + A    +L+LQ +++   K   Q E  +  +  
Sbjct: 1617 RAQQQAEAERAREEAERELERWQLKANEAL---RLRLQAEEVAQQKSLAQAEAEKQKEEA 1673

Query: 766  EQRDTMVTKLHSQ-IRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHT 824
            E+      K   Q +RQ +   +E   Q Q            +AE   + + A  +    
Sbjct: 1674 EREARRRGKAEEQAVRQRELAEQELEKQRQ------------LAEGTAQQRLAAEQ---- 1717

Query: 825  ELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK---EVEMMK 881
                 ++ +  + +E  +QQ + L  +L  L        ++ Q   ++  K   E+E++ 
Sbjct: 1718 -----ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1772

Query: 882  AAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQL 941
            A+  +  E++RS   +  QRL+    R  EL    A+   L  E K+       +   + 
Sbjct: 1773 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ------RQLAEE 1826

Query: 942  QAAESRYEAQKRITQVFELEILDLYGRL--EKDGLLKKLEEEKAEAAEAAEE 991
             AA  R EA++ + +  +L  +    RL  E +  LK+ E E       AE+
Sbjct: 1827 DAARQRAEAERVLAE--KLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1876



 Score = 33.9 bits (76), Expect = 0.93
 Identities = 49/269 (18%), Positives = 108/269 (40%), Gaps = 52/269 (19%)

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
            ++ +++ W+  + +   R+  +  Q D    +L    RQL++ RE     +  L   L+D
Sbjct: 1174 RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE----SADPLGAWLQD 1229

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
             R    +++                    +  L++S++V++Q+    RQ   L E  E +
Sbjct: 1230 ARRRQEQIQ--------------------AMPLADSQAVREQL----RQEQALLEEIERH 1265

Query: 863  LEQLQ------NKHSDTTKEVEMMKAAYRKELE------------KNRSHVLQQTQRLDT 904
             E+++       ++ +  K+ E+    Y+ +LE                 V+Q+   L T
Sbjct: 1266 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1325

Query: 905  SQKRILELESH----LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
                +  L S     +++    + E+++  E  + + R +L   E+  E Q+++ +    
Sbjct: 1326 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1385

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAA 989
                     E   L ++++EE     EAA
Sbjct: 1386 --AKAQAEREAKELQQRMQEEVVRREEAA 1412


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 65/295 (22%), Positives = 134/295 (45%), Gaps = 21/295 (7%)

Query: 711  QHALRNRRLL------RKVIKAAALEEHNAAMKDQLKLQ-EKDIQMWKVSLQKEQARYNQ 763
            Q A R R+L       ++ +    L+E   A+++  +L+ E ++   +  L +EQAR  +
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR--R 2345

Query: 764  LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
            LQE ++ M  +L  + +  Q   E    +  E+  + E  +  +AE+     +A      
Sbjct: 2346 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405

Query: 824  TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-MMKA 882
                  ++ +KL  +E   Q+   L + L +  + ++   E+L+   ++  +E E + + 
Sbjct: 2406 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2465

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA----R 938
            A   +L+      +QQ Q L  +Q      +S L++KD  LL++++++E  K +     +
Sbjct: 2466 AKLLQLKSEEMQTVQQEQLLQETQAL---QQSFLSEKDS-LLQRERFIEQEKAKLEQLFQ 2521

Query: 939  GQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERL 993
             ++  A+   E Q+R  Q  E E   L   +E+    ++ + E  E     +E L
Sbjct: 2522 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEE---ARRRQHEAEEGVRRKQEEL 2573



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 62/307 (20%), Positives = 131/307 (42%), Gaps = 30/307 (9%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK----LQEKDIQMWKVSLQKEQAR 760
            ER +RQ      R+   +V  A+ ++    A +++ +    L+E  +Q  +   +  QA 
Sbjct: 1497 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1556

Query: 761  YNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNK 820
              + ++ +  + T   S   +LQ  R  F  ++ +L+  L++    +A+LR E ++   +
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616

Query: 821  VCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-- 878
                E    +  ++L   +    +   L  Q   + +   L   + + +  +  +E    
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676

Query: 879  --------MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL 930
                      +    +ELEK R       Q+   +++ ++ L +   + +    +Q++ L
Sbjct: 1677 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE----QQRQLL 1732

Query: 931  EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLL---KKLEEEKAEAAE 987
            E+    AR Q +AA +    QKR  Q  E E+  +  R E + LL    + EEE    +E
Sbjct: 1733 EEE--LARLQREAAAA---TQKR--QELEAELAKV--RAEMEVLLASKARAEEESRSTSE 1783

Query: 988  AAEERLD 994
             +++RL+
Sbjct: 1784 KSKQRLE 1790



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/315 (22%), Positives = 131/315 (41%), Gaps = 38/315 (12%)

Query: 711  QHALRNRRLLRKVIKAA-ALEEHNAAMKDQLKLQ-------EKDIQMWKVSLQKEQARYN 762
            +  LR RR + + I A  A  E  AA K +L+L+        +D    K   + E AR  
Sbjct: 1914 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1973

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            QL  + +    +   ++++     EE   Q +    ++E  +  + E R   ++A  +  
Sbjct: 1974 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA 2033

Query: 823  HTELLLSQVSQKLSNSE------SVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK- 875
                L  + +QK   +E      +VQQ+ + L + L    +  +  L+QL+ +     + 
Sbjct: 2034 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL----QQEQSVLDQLRGEAEAARRA 2089

Query: 876  --EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
              E E  +    +E  ++R  V ++ +RL  S +   +  +        L ++ +     
Sbjct: 2090 AEEAEEARVQAEREAAQSRRQV-EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148

Query: 934  KLQARG----QLQAAESRYEAQKRITQV-------FELEILDLYGRLEKDGLLKKLEEE- 981
            + QA      Q QAA++  E  K+  +         E E+  L  +LE+    K L +E 
Sbjct: 2149 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2208

Query: 982  ----KAEAAEAAEER 992
                KAEA EAA +R
Sbjct: 2209 LQRLKAEATEAARQR 2223



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKL 742
            S+E++T++ + LL   Q L + F  ++ +L  R R + ++  K   L +   A   QL+ 
Sbjct: 2473 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR- 2531

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
                        +++Q +  Q++++R  +V  +  + R+ QH+ EE   + QE   +LE 
Sbjct: 2532 ------------EEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQEELQQLEQ 2578

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESV 841
             R    EL  E  +   +    +LL  Q    L++SE V
Sbjct: 2579 QRRQQEELLAEENQRLRE--QLQLLEEQHRAALAHSEEV 2615



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 38/292 (13%)

Query: 706  RFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQ 765
            R ++Q  A R R    + ++   L+ + A    +L+LQ +++   K   Q E  +  +  
Sbjct: 1613 RAQQQAEAERAREEAERELERWQLKANEAL---RLRLQAEEVAQQKSLAQAEAEKQKEEA 1669

Query: 766  EQRDTMVTKLHSQ-IRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHT 824
            E+      K   Q +RQ +   +E   Q Q            +AE   + + A  +    
Sbjct: 1670 EREARRRGKAEEQAVRQRELAEQELEKQRQ------------LAEGTAQQRLAAEQ---- 1713

Query: 825  ELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK---EVEMMK 881
                 ++ +  + +E  +QQ + L  +L  L        ++ Q   ++  K   E+E++ 
Sbjct: 1714 -----ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768

Query: 882  AAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQL 941
            A+  +  E++RS   +  QRL+    R  EL    A+   L  E K+       +   + 
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ------RQLAEE 1822

Query: 942  QAAESRYEAQKRITQVFELEILDLYGRL--EKDGLLKKLEEEKAEAAEAAEE 991
             AA  R EA++ + +  +L  +    RL  E +  LK+ E E       AE+
Sbjct: 1823 DAARQRAEAERVLAE--KLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872



 Score = 33.9 bits (76), Expect = 0.93
 Identities = 49/269 (18%), Positives = 108/269 (40%), Gaps = 52/269 (19%)

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
            ++ +++ W+  + +   R+  +  Q D    +L    RQL++ RE     +  L   L+D
Sbjct: 1170 RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE----SADPLGAWLQD 1225

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
             R    +++                    +  L++S++V++Q+    RQ   L E  E +
Sbjct: 1226 ARRRQEQIQ--------------------AMPLADSQAVREQL----RQEQALLEEIERH 1261

Query: 863  LEQLQ------NKHSDTTKEVEMMKAAYRKELE------------KNRSHVLQQTQRLDT 904
             E+++       ++ +  K+ E+    Y+ +LE                 V+Q+   L T
Sbjct: 1262 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1321

Query: 905  SQKRILELESH----LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
                +  L S     +++    + E+++  E  + + R +L   E+  E Q+++ +    
Sbjct: 1322 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1381

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAA 989
                     E   L ++++EE     EAA
Sbjct: 1382 --AKAQAEREAKELQQRMQEEVVRREEAA 1408


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 65/295 (22%), Positives = 134/295 (45%), Gaps = 21/295 (7%)

Query: 711  QHALRNRRLL------RKVIKAAALEEHNAAMKDQLKLQ-EKDIQMWKVSLQKEQARYNQ 763
            Q A R R+L       ++ +    L+E   A+++  +L+ E ++   +  L +EQAR  +
Sbjct: 2256 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR--R 2313

Query: 764  LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
            LQE ++ M  +L  + +  Q   E    +  E+  + E  +  +AE+     +A      
Sbjct: 2314 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2373

Query: 824  TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-MMKA 882
                  ++ +KL  +E   Q+   L + L +  + ++   E+L+   ++  +E E + + 
Sbjct: 2374 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2433

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA----R 938
            A   +L+      +QQ Q L  +Q      +S L++KD  LL++++++E  K +     +
Sbjct: 2434 AKLLQLKSEEMQTVQQEQLLQETQAL---QQSFLSEKDS-LLQRERFIEQEKAKLEQLFQ 2489

Query: 939  GQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERL 993
             ++  A+   E Q+R  Q  E E   L   +E+    ++ + E  E     +E L
Sbjct: 2490 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEE---ARRRQHEAEEGVRRKQEEL 2541



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 62/307 (20%), Positives = 131/307 (42%), Gaps = 30/307 (9%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK----LQEKDIQMWKVSLQKEQAR 760
            ER +RQ      R+   +V  A+ ++    A +++ +    L+E  +Q  +   +  QA 
Sbjct: 1465 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1524

Query: 761  YNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNK 820
              + ++ +  + T   S   +LQ  R  F  ++ +L+  L++    +A+LR E ++   +
Sbjct: 1525 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584

Query: 821  VCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-- 878
                E    +  ++L   +    +   L  Q   + +   L   + + +  +  +E    
Sbjct: 1585 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1644

Query: 879  --------MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL 930
                      +    +ELEK R       Q+   +++ ++ L +   + +    +Q++ L
Sbjct: 1645 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE----QQRQLL 1700

Query: 931  EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLL---KKLEEEKAEAAE 987
            E+    AR Q +AA +    QKR  Q  E E+  +  R E + LL    + EEE    +E
Sbjct: 1701 EEE--LARLQREAAAA---TQKR--QELEAELAKV--RAEMEVLLASKARAEEESRSTSE 1751

Query: 988  AAEERLD 994
             +++RL+
Sbjct: 1752 KSKQRLE 1758



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/315 (22%), Positives = 131/315 (41%), Gaps = 38/315 (12%)

Query: 711  QHALRNRRLLRKVIKAA-ALEEHNAAMKDQLKLQ-------EKDIQMWKVSLQKEQARYN 762
            +  LR RR + + I A  A  E  AA K +L+L+        +D    K   + E AR  
Sbjct: 1882 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1941

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            QL  + +    +   ++++     EE   Q +    ++E  +  + E R   ++A  +  
Sbjct: 1942 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA 2001

Query: 823  HTELLLSQVSQKLSNSE------SVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK- 875
                L  + +QK   +E      +VQQ+ + L + L    +  +  L+QL+ +     + 
Sbjct: 2002 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL----QQEQSVLDQLRGEAEAARRA 2057

Query: 876  --EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
              E E  +    +E  ++R  V ++ +RL  S +   +  +        L ++ +     
Sbjct: 2058 AEEAEEARVQAEREAAQSRRQV-EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2116

Query: 934  KLQARG----QLQAAESRYEAQKRITQV-------FELEILDLYGRLEKDGLLKKLEEE- 981
            + QA      Q QAA++  E  K+  +         E E+  L  +LE+    K L +E 
Sbjct: 2117 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2176

Query: 982  ----KAEAAEAAEER 992
                KAEA EAA +R
Sbjct: 2177 LQRLKAEATEAARQR 2191



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKL 742
            S+E++T++ + LL   Q L + F  ++ +L  R R + ++  K   L +   A   QL+ 
Sbjct: 2441 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR- 2499

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
                        +++Q +  Q++++R  +V  +  + R+ QH+ EE   + QE   +LE 
Sbjct: 2500 ------------EEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQEELQQLEQ 2546

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESV 841
             R    EL  E  +   +    +LL  Q    L++SE V
Sbjct: 2547 QRRQQEELLAEENQRLRE--QLQLLEEQHRAALAHSEEV 2583



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 38/292 (13%)

Query: 706  RFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQ 765
            R ++Q  A R R    + ++   L+ + A    +L+LQ +++   K   Q E  +  +  
Sbjct: 1581 RAQQQAEAERAREEAERELERWQLKANEAL---RLRLQAEEVAQQKSLAQAEAEKQKEEA 1637

Query: 766  EQRDTMVTKLHSQ-IRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHT 824
            E+      K   Q +RQ +   +E   Q Q            +AE   + + A  +    
Sbjct: 1638 EREARRRGKAEEQAVRQRELAEQELEKQRQ------------LAEGTAQQRLAAEQ---- 1681

Query: 825  ELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK---EVEMMK 881
                 ++ +  + +E  +QQ + L  +L  L        ++ Q   ++  K   E+E++ 
Sbjct: 1682 -----ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1736

Query: 882  AAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQL 941
            A+  +  E++RS   +  QRL+    R  EL    A+   L  E K+       +   + 
Sbjct: 1737 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ------RQLAEE 1790

Query: 942  QAAESRYEAQKRITQVFELEILDLYGRL--EKDGLLKKLEEEKAEAAEAAEE 991
             AA  R EA++ + +  +L  +    RL  E +  LK+ E E       AE+
Sbjct: 1791 DAARQRAEAERVLAE--KLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1840



 Score = 33.9 bits (76), Expect = 0.93
 Identities = 49/269 (18%), Positives = 108/269 (40%), Gaps = 52/269 (19%)

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
            ++ +++ W+  + +   R+  +  Q D    +L    RQL++ RE     +  L   L+D
Sbjct: 1138 RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE----SADPLGAWLQD 1193

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
             R    +++                    +  L++S++V++Q+    RQ   L E  E +
Sbjct: 1194 ARRRQEQIQ--------------------AMPLADSQAVREQL----RQEQALLEEIERH 1229

Query: 863  LEQLQ------NKHSDTTKEVEMMKAAYRKELE------------KNRSHVLQQTQRLDT 904
             E+++       ++ +  K+ E+    Y+ +LE                 V+Q+   L T
Sbjct: 1230 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1289

Query: 905  SQKRILELESH----LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
                +  L S     +++    + E+++  E  + + R +L   E+  E Q+++ +    
Sbjct: 1290 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1349

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAA 989
                     E   L ++++EE     EAA
Sbjct: 1350 --AKAQAEREAKELQQRMQEEVVRREEAA 1376


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 65/295 (22%), Positives = 134/295 (45%), Gaps = 21/295 (7%)

Query: 711  QHALRNRRLL------RKVIKAAALEEHNAAMKDQLKLQ-EKDIQMWKVSLQKEQARYNQ 763
            Q A R R+L       ++ +    L+E   A+++  +L+ E ++   +  L +EQAR  +
Sbjct: 2425 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR--R 2482

Query: 764  LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
            LQE ++ M  +L  + +  Q   E    +  E+  + E  +  +AE+     +A      
Sbjct: 2483 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2542

Query: 824  TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-MMKA 882
                  ++ +KL  +E   Q+   L + L +  + ++   E+L+   ++  +E E + + 
Sbjct: 2543 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2602

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA----R 938
            A   +L+      +QQ Q L  +Q      +S L++KD  LL++++++E  K +     +
Sbjct: 2603 AKLLQLKSEEMQTVQQEQLLQETQAL---QQSFLSEKDS-LLQRERFIEQEKAKLEQLFQ 2658

Query: 939  GQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERL 993
             ++  A+   E Q+R  Q  E E   L   +E+    ++ + E  E     +E L
Sbjct: 2659 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEE---ARRRQHEAEEGVRRKQEEL 2710



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 62/307 (20%), Positives = 131/307 (42%), Gaps = 30/307 (9%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK----LQEKDIQMWKVSLQKEQAR 760
            ER +RQ      R+   +V  A+ ++    A +++ +    L+E  +Q  +   +  QA 
Sbjct: 1634 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1693

Query: 761  YNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNK 820
              + ++ +  + T   S   +LQ  R  F  ++ +L+  L++    +A+LR E ++   +
Sbjct: 1694 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753

Query: 821  VCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-- 878
                E    +  ++L   +    +   L  Q   + +   L   + + +  +  +E    
Sbjct: 1754 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1813

Query: 879  --------MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL 930
                      +    +ELEK R       Q+   +++ ++ L +   + +    +Q++ L
Sbjct: 1814 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE----QQRQLL 1869

Query: 931  EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLL---KKLEEEKAEAAE 987
            E+    AR Q +AA +    QKR  Q  E E+  +  R E + LL    + EEE    +E
Sbjct: 1870 EEE--LARLQREAAAA---TQKR--QELEAELAKV--RAEMEVLLASKARAEEESRSTSE 1920

Query: 988  AAEERLD 994
             +++RL+
Sbjct: 1921 KSKQRLE 1927



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/315 (22%), Positives = 131/315 (41%), Gaps = 38/315 (12%)

Query: 711  QHALRNRRLLRKVIKAA-ALEEHNAAMKDQLKLQ-------EKDIQMWKVSLQKEQARYN 762
            +  LR RR + + I A  A  E  AA K +L+L+        +D    K   + E AR  
Sbjct: 2051 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 2110

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            QL  + +    +   ++++     EE   Q +    ++E  +  + E R   ++A  +  
Sbjct: 2111 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA 2170

Query: 823  HTELLLSQVSQKLSNSE------SVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK- 875
                L  + +QK   +E      +VQQ+ + L + L    +  +  L+QL+ +     + 
Sbjct: 2171 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL----QQEQSVLDQLRGEAEAARRA 2226

Query: 876  --EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
              E E  +    +E  ++R  V ++ +RL  S +   +  +        L ++ +     
Sbjct: 2227 AEEAEEARVQAEREAAQSRRQV-EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2285

Query: 934  KLQARG----QLQAAESRYEAQKRITQV-------FELEILDLYGRLEKDGLLKKLEEE- 981
            + QA      Q QAA++  E  K+  +         E E+  L  +LE+    K L +E 
Sbjct: 2286 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2345

Query: 982  ----KAEAAEAAEER 992
                KAEA EAA +R
Sbjct: 2346 LQRLKAEATEAARQR 2360



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKL 742
            S+E++T++ + LL   Q L + F  ++ +L  R R + ++  K   L +   A   QL+ 
Sbjct: 2610 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR- 2668

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
                        +++Q +  Q++++R  +V  +  + R+ QH+ EE   + QE   +LE 
Sbjct: 2669 ------------EEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQEELQQLEQ 2715

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESV 841
             R    EL  E  +   +    +LL  Q    L++SE V
Sbjct: 2716 QRRQQEELLAEENQRLRE--QLQLLEEQHRAALAHSEEV 2752



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 38/292 (13%)

Query: 706  RFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQ 765
            R ++Q  A R R    + ++   L+ + A    +L+LQ +++   K   Q E  +  +  
Sbjct: 1750 RAQQQAEAERAREEAERELERWQLKANEAL---RLRLQAEEVAQQKSLAQAEAEKQKEEA 1806

Query: 766  EQRDTMVTKLHSQ-IRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHT 824
            E+      K   Q +RQ +   +E   Q Q            +AE   + + A  +    
Sbjct: 1807 EREARRRGKAEEQAVRQRELAEQELEKQRQ------------LAEGTAQQRLAAEQ---- 1850

Query: 825  ELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK---EVEMMK 881
                 ++ +  + +E  +QQ + L  +L  L        ++ Q   ++  K   E+E++ 
Sbjct: 1851 -----ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1905

Query: 882  AAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQL 941
            A+  +  E++RS   +  QRL+    R  EL    A+   L  E K+       +   + 
Sbjct: 1906 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ------RQLAEE 1959

Query: 942  QAAESRYEAQKRITQVFELEILDLYGRL--EKDGLLKKLEEEKAEAAEAAEE 991
             AA  R EA++ + +  +L  +    RL  E +  LK+ E E       AE+
Sbjct: 1960 DAARQRAEAERVLAE--KLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 2009



 Score = 33.9 bits (76), Expect = 0.93
 Identities = 49/269 (18%), Positives = 108/269 (40%), Gaps = 52/269 (19%)

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
            ++ +++ W+  + +   R+  +  Q D    +L    RQL++ RE     +  L   L+D
Sbjct: 1307 RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE----SADPLGAWLQD 1362

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
             R    +++                    +  L++S++V++Q+    RQ   L E  E +
Sbjct: 1363 ARRRQEQIQ--------------------AMPLADSQAVREQL----RQEQALLEEIERH 1398

Query: 863  LEQLQ------NKHSDTTKEVEMMKAAYRKELE------------KNRSHVLQQTQRLDT 904
             E+++       ++ +  K+ E+    Y+ +LE                 V+Q+   L T
Sbjct: 1399 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1458

Query: 905  SQKRILELESH----LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
                +  L S     +++    + E+++  E  + + R +L   E+  E Q+++ +    
Sbjct: 1459 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1518

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAA 989
                     E   L ++++EE     EAA
Sbjct: 1519 --AKAQAEREAKELQQRMQEEVVRREEAA 1545


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 65/295 (22%), Positives = 134/295 (45%), Gaps = 21/295 (7%)

Query: 711  QHALRNRRLL------RKVIKAAALEEHNAAMKDQLKLQ-EKDIQMWKVSLQKEQARYNQ 763
            Q A R R+L       ++ +    L+E   A+++  +L+ E ++   +  L +EQAR  +
Sbjct: 2266 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR--R 2323

Query: 764  LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
            LQE ++ M  +L  + +  Q   E    +  E+  + E  +  +AE+     +A      
Sbjct: 2324 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2383

Query: 824  TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-MMKA 882
                  ++ +KL  +E   Q+   L + L +  + ++   E+L+   ++  +E E + + 
Sbjct: 2384 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2443

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA----R 938
            A   +L+      +QQ Q L  +Q      +S L++KD  LL++++++E  K +     +
Sbjct: 2444 AKLLQLKSEEMQTVQQEQLLQETQAL---QQSFLSEKDS-LLQRERFIEQEKAKLEQLFQ 2499

Query: 939  GQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERL 993
             ++  A+   E Q+R  Q  E E   L   +E+    ++ + E  E     +E L
Sbjct: 2500 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEE---ARRRQHEAEEGVRRKQEEL 2551



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 62/307 (20%), Positives = 131/307 (42%), Gaps = 30/307 (9%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK----LQEKDIQMWKVSLQKEQAR 760
            ER +RQ      R+   +V  A+ ++    A +++ +    L+E  +Q  +   +  QA 
Sbjct: 1475 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1534

Query: 761  YNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNK 820
              + ++ +  + T   S   +LQ  R  F  ++ +L+  L++    +A+LR E ++   +
Sbjct: 1535 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594

Query: 821  VCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-- 878
                E    +  ++L   +    +   L  Q   + +   L   + + +  +  +E    
Sbjct: 1595 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1654

Query: 879  --------MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL 930
                      +    +ELEK R       Q+   +++ ++ L +   + +    +Q++ L
Sbjct: 1655 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE----QQRQLL 1710

Query: 931  EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLL---KKLEEEKAEAAE 987
            E+    AR Q +AA +    QKR  Q  E E+  +  R E + LL    + EEE    +E
Sbjct: 1711 EEE--LARLQREAAAA---TQKR--QELEAELAKV--RAEMEVLLASKARAEEESRSTSE 1761

Query: 988  AAEERLD 994
             +++RL+
Sbjct: 1762 KSKQRLE 1768



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/315 (22%), Positives = 131/315 (41%), Gaps = 38/315 (12%)

Query: 711  QHALRNRRLLRKVIKAA-ALEEHNAAMKDQLKLQ-------EKDIQMWKVSLQKEQARYN 762
            +  LR RR + + I A  A  E  AA K +L+L+        +D    K   + E AR  
Sbjct: 1892 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1951

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            QL  + +    +   ++++     EE   Q +    ++E  +  + E R   ++A  +  
Sbjct: 1952 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA 2011

Query: 823  HTELLLSQVSQKLSNSE------SVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK- 875
                L  + +QK   +E      +VQQ+ + L + L    +  +  L+QL+ +     + 
Sbjct: 2012 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL----QQEQSVLDQLRGEAEAARRA 2067

Query: 876  --EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
              E E  +    +E  ++R  V ++ +RL  S +   +  +        L ++ +     
Sbjct: 2068 AEEAEEARVQAEREAAQSRRQV-EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2126

Query: 934  KLQARG----QLQAAESRYEAQKRITQV-------FELEILDLYGRLEKDGLLKKLEEE- 981
            + QA      Q QAA++  E  K+  +         E E+  L  +LE+    K L +E 
Sbjct: 2127 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2186

Query: 982  ----KAEAAEAAEER 992
                KAEA EAA +R
Sbjct: 2187 LQRLKAEATEAARQR 2201



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKL 742
            S+E++T++ + LL   Q L + F  ++ +L  R R + ++  K   L +   A   QL+ 
Sbjct: 2451 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR- 2509

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
                        +++Q +  Q++++R  +V  +  + R+ QH+ EE   + QE   +LE 
Sbjct: 2510 ------------EEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQEELQQLEQ 2556

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESV 841
             R    EL  E  +   +    +LL  Q    L++SE V
Sbjct: 2557 QRRQQEELLAEENQRLRE--QLQLLEEQHRAALAHSEEV 2593



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 38/292 (13%)

Query: 706  RFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQ 765
            R ++Q  A R R    + ++   L+ + A    +L+LQ +++   K   Q E  +  +  
Sbjct: 1591 RAQQQAEAERAREEAERELERWQLKANEAL---RLRLQAEEVAQQKSLAQAEAEKQKEEA 1647

Query: 766  EQRDTMVTKLHSQ-IRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHT 824
            E+      K   Q +RQ +   +E   Q Q            +AE   + + A  +    
Sbjct: 1648 EREARRRGKAEEQAVRQRELAEQELEKQRQ------------LAEGTAQQRLAAEQ---- 1691

Query: 825  ELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK---EVEMMK 881
                 ++ +  + +E  +QQ + L  +L  L        ++ Q   ++  K   E+E++ 
Sbjct: 1692 -----ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1746

Query: 882  AAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQL 941
            A+  +  E++RS   +  QRL+    R  EL    A+   L  E K+       +   + 
Sbjct: 1747 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ------RQLAEE 1800

Query: 942  QAAESRYEAQKRITQVFELEILDLYGRL--EKDGLLKKLEEEKAEAAEAAEE 991
             AA  R EA++ + +  +L  +    RL  E +  LK+ E E       AE+
Sbjct: 1801 DAARQRAEAERVLAE--KLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1850



 Score = 33.9 bits (76), Expect = 0.93
 Identities = 49/269 (18%), Positives = 108/269 (40%), Gaps = 52/269 (19%)

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
            ++ +++ W+  + +   R+  +  Q D    +L    RQL++ RE     +  L   L+D
Sbjct: 1148 RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE----SADPLGAWLQD 1203

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
             R    +++                    +  L++S++V++Q+    RQ   L E  E +
Sbjct: 1204 ARRRQEQIQ--------------------AMPLADSQAVREQL----RQEQALLEEIERH 1239

Query: 863  LEQLQ------NKHSDTTKEVEMMKAAYRKELE------------KNRSHVLQQTQRLDT 904
             E+++       ++ +  K+ E+    Y+ +LE                 V+Q+   L T
Sbjct: 1240 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1299

Query: 905  SQKRILELESH----LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
                +  L S     +++    + E+++  E  + + R +L   E+  E Q+++ +    
Sbjct: 1300 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1359

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAA 989
                     E   L ++++EE     EAA
Sbjct: 1360 --AKAQAEREAKELQQRMQEEVVRREEAA 1386


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 65/295 (22%), Positives = 134/295 (45%), Gaps = 21/295 (7%)

Query: 711  QHALRNRRLL------RKVIKAAALEEHNAAMKDQLKLQ-EKDIQMWKVSLQKEQARYNQ 763
            Q A R R+L       ++ +    L+E   A+++  +L+ E ++   +  L +EQAR  +
Sbjct: 2274 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR--R 2331

Query: 764  LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
            LQE ++ M  +L  + +  Q   E    +  E+  + E  +  +AE+     +A      
Sbjct: 2332 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2391

Query: 824  TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-MMKA 882
                  ++ +KL  +E   Q+   L + L +  + ++   E+L+   ++  +E E + + 
Sbjct: 2392 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2451

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA----R 938
            A   +L+      +QQ Q L  +Q      +S L++KD  LL++++++E  K +     +
Sbjct: 2452 AKLLQLKSEEMQTVQQEQLLQETQAL---QQSFLSEKDS-LLQRERFIEQEKAKLEQLFQ 2507

Query: 939  GQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERL 993
             ++  A+   E Q+R  Q  E E   L   +E+    ++ + E  E     +E L
Sbjct: 2508 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEE---ARRRQHEAEEGVRRKQEEL 2559



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 62/307 (20%), Positives = 131/307 (42%), Gaps = 30/307 (9%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK----LQEKDIQMWKVSLQKEQAR 760
            ER +RQ      R+   +V  A+ ++    A +++ +    L+E  +Q  +   +  QA 
Sbjct: 1483 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1542

Query: 761  YNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNK 820
              + ++ +  + T   S   +LQ  R  F  ++ +L+  L++    +A+LR E ++   +
Sbjct: 1543 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1602

Query: 821  VCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-- 878
                E    +  ++L   +    +   L  Q   + +   L   + + +  +  +E    
Sbjct: 1603 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1662

Query: 879  --------MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL 930
                      +    +ELEK R       Q+   +++ ++ L +   + +    +Q++ L
Sbjct: 1663 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE----QQRQLL 1718

Query: 931  EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLL---KKLEEEKAEAAE 987
            E+    AR Q +AA +    QKR  Q  E E+  +  R E + LL    + EEE    +E
Sbjct: 1719 EEE--LARLQREAAAA---TQKR--QELEAELAKV--RAEMEVLLASKARAEEESRSTSE 1769

Query: 988  AAEERLD 994
             +++RL+
Sbjct: 1770 KSKQRLE 1776



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/315 (22%), Positives = 131/315 (41%), Gaps = 38/315 (12%)

Query: 711  QHALRNRRLLRKVIKAA-ALEEHNAAMKDQLKLQ-------EKDIQMWKVSLQKEQARYN 762
            +  LR RR + + I A  A  E  AA K +L+L+        +D    K   + E AR  
Sbjct: 1900 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 1959

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            QL  + +    +   ++++     EE   Q +    ++E  +  + E R   ++A  +  
Sbjct: 1960 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA 2019

Query: 823  HTELLLSQVSQKLSNSE------SVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK- 875
                L  + +QK   +E      +VQQ+ + L + L    +  +  L+QL+ +     + 
Sbjct: 2020 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL----QQEQSVLDQLRGEAEAARRA 2075

Query: 876  --EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
              E E  +    +E  ++R  V ++ +RL  S +   +  +        L ++ +     
Sbjct: 2076 AEEAEEARVQAEREAAQSRRQV-EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2134

Query: 934  KLQARG----QLQAAESRYEAQKRITQV-------FELEILDLYGRLEKDGLLKKLEEE- 981
            + QA      Q QAA++  E  K+  +         E E+  L  +LE+    K L +E 
Sbjct: 2135 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2194

Query: 982  ----KAEAAEAAEER 992
                KAEA EAA +R
Sbjct: 2195 LQRLKAEATEAARQR 2209



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKL 742
            S+E++T++ + LL   Q L + F  ++ +L  R R + ++  K   L +   A   QL+ 
Sbjct: 2459 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR- 2517

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
                        +++Q +  Q++++R  +V  +  + R+ QH+ EE   + QE   +LE 
Sbjct: 2518 ------------EEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQEELQQLEQ 2564

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESV 841
             R    EL  E  +   +    +LL  Q    L++SE V
Sbjct: 2565 QRRQQEELLAEENQRLRE--QLQLLEEQHRAALAHSEEV 2601



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 38/292 (13%)

Query: 706  RFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQ 765
            R ++Q  A R R    + ++   L+ + A    +L+LQ +++   K   Q E  +  +  
Sbjct: 1599 RAQQQAEAERAREEAERELERWQLKANEAL---RLRLQAEEVAQQKSLAQAEAEKQKEEA 1655

Query: 766  EQRDTMVTKLHSQ-IRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHT 824
            E+      K   Q +RQ +   +E   Q Q            +AE   + + A  +    
Sbjct: 1656 EREARRRGKAEEQAVRQRELAEQELEKQRQ------------LAEGTAQQRLAAEQ---- 1699

Query: 825  ELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK---EVEMMK 881
                 ++ +  + +E  +QQ + L  +L  L        ++ Q   ++  K   E+E++ 
Sbjct: 1700 -----ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1754

Query: 882  AAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQL 941
            A+  +  E++RS   +  QRL+    R  EL    A+   L  E K+       +   + 
Sbjct: 1755 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ------RQLAEE 1808

Query: 942  QAAESRYEAQKRITQVFELEILDLYGRL--EKDGLLKKLEEEKAEAAEAAEE 991
             AA  R EA++ + +  +L  +    RL  E +  LK+ E E       AE+
Sbjct: 1809 DAARQRAEAERVLAE--KLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1858



 Score = 33.9 bits (76), Expect = 0.93
 Identities = 49/269 (18%), Positives = 108/269 (40%), Gaps = 52/269 (19%)

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
            ++ +++ W+  + +   R+  +  Q D    +L    RQL++ RE     +  L   L+D
Sbjct: 1156 RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE----SADPLGAWLQD 1211

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
             R    +++                    +  L++S++V++Q+    RQ   L E  E +
Sbjct: 1212 ARRRQEQIQ--------------------AMPLADSQAVREQL----RQEQALLEEIERH 1247

Query: 863  LEQLQ------NKHSDTTKEVEMMKAAYRKELE------------KNRSHVLQQTQRLDT 904
             E+++       ++ +  K+ E+    Y+ +LE                 V+Q+   L T
Sbjct: 1248 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1307

Query: 905  SQKRILELESH----LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
                +  L S     +++    + E+++  E  + + R +L   E+  E Q+++ +    
Sbjct: 1308 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1367

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAA 989
                     E   L ++++EE     EAA
Sbjct: 1368 --AKAQAEREAKELQQRMQEEVVRREEAA 1394


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 65/295 (22%), Positives = 134/295 (45%), Gaps = 21/295 (7%)

Query: 711  QHALRNRRLL------RKVIKAAALEEHNAAMKDQLKLQ-EKDIQMWKVSLQKEQARYNQ 763
            Q A R R+L       ++ +    L+E   A+++  +L+ E ++   +  L +EQAR  +
Sbjct: 2315 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR--R 2372

Query: 764  LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
            LQE ++ M  +L  + +  Q   E    +  E+  + E  +  +AE+     +A      
Sbjct: 2373 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2432

Query: 824  TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-MMKA 882
                  ++ +KL  +E   Q+   L + L +  + ++   E+L+   ++  +E E + + 
Sbjct: 2433 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2492

Query: 883  AYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA----R 938
            A   +L+      +QQ Q L  +Q      +S L++KD  LL++++++E  K +     +
Sbjct: 2493 AKLLQLKSEEMQTVQQEQLLQETQAL---QQSFLSEKDS-LLQRERFIEQEKAKLEQLFQ 2548

Query: 939  GQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERL 993
             ++  A+   E Q+R  Q  E E   L   +E+    ++ + E  E     +E L
Sbjct: 2549 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEE---ARRRQHEAEEGVRRKQEEL 2600



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 62/307 (20%), Positives = 131/307 (42%), Gaps = 30/307 (9%)

Query: 705  ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLK----LQEKDIQMWKVSLQKEQAR 760
            ER +RQ      R+   +V  A+ ++    A +++ +    L+E  +Q  +   +  QA 
Sbjct: 1524 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1583

Query: 761  YNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNK 820
              + ++ +  + T   S   +LQ  R  F  ++ +L+  L++    +A+LR E ++   +
Sbjct: 1584 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1643

Query: 821  VCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVE-- 878
                E    +  ++L   +    +   L  Q   + +   L   + + +  +  +E    
Sbjct: 1644 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1703

Query: 879  --------MMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYL 930
                      +    +ELEK R       Q+   +++ ++ L +   + +    +Q++ L
Sbjct: 1704 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE----QQRQLL 1759

Query: 931  EDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLL---KKLEEEKAEAAE 987
            E+    AR Q +AA +    QKR  Q  E E+  +  R E + LL    + EEE    +E
Sbjct: 1760 EEE--LARLQREAAAA---TQKR--QELEAELAKV--RAEMEVLLASKARAEEESRSTSE 1810

Query: 988  AAEERLD 994
             +++RL+
Sbjct: 1811 KSKQRLE 1817



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/315 (22%), Positives = 131/315 (41%), Gaps = 38/315 (12%)

Query: 711  QHALRNRRLLRKVIKAA-ALEEHNAAMKDQLKLQ-------EKDIQMWKVSLQKEQARYN 762
            +  LR RR + + I A  A  E  AA K +L+L+        +D    K   + E AR  
Sbjct: 1941 EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQR 2000

Query: 763  QLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVC 822
            QL  + +    +   ++++     EE   Q +    ++E  +  + E R   ++A  +  
Sbjct: 2001 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESA 2060

Query: 823  HTELLLSQVSQKLSNSE------SVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK- 875
                L  + +QK   +E      +VQQ+ + L + L    +  +  L+QL+ +     + 
Sbjct: 2061 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTL----QQEQSVLDQLRGEAEAARRA 2116

Query: 876  --EVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDV 933
              E E  +    +E  ++R  V ++ +RL  S +   +  +        L ++ +     
Sbjct: 2117 AEEAEEARVQAEREAAQSRRQV-EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2175

Query: 934  KLQARG----QLQAAESRYEAQKRITQV-------FELEILDLYGRLEKDGLLKKLEEE- 981
            + QA      Q QAA++  E  K+  +         E E+  L  +LE+    K L +E 
Sbjct: 2176 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2235

Query: 982  ----KAEAAEAAEER 992
                KAEA EAA +R
Sbjct: 2236 LQRLKAEATEAARQR 2250



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHAL--RNRRLLRKVIKAAALEEHNAAMKDQLKL 742
            S+E++T++ + LL   Q L + F  ++ +L  R R + ++  K   L +   A   QL+ 
Sbjct: 2500 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR- 2558

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
                        +++Q +  Q++++R  +V  +  + R+ QH+ EE   + QE   +LE 
Sbjct: 2559 ------------EEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQEELQQLEQ 2605

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESV 841
             R    EL  E  +   +    +LL  Q    L++SE V
Sbjct: 2606 QRRQQEELLAEENQRLRE--QLQLLEEQHRAALAHSEEV 2642



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 63/292 (21%), Positives = 119/292 (40%), Gaps = 38/292 (13%)

Query: 706  RFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQ 765
            R ++Q  A R R    + ++   L+ + A    +L+LQ +++   K   Q E  +  +  
Sbjct: 1640 RAQQQAEAERAREEAERELERWQLKANEAL---RLRLQAEEVAQQKSLAQAEAEKQKEEA 1696

Query: 766  EQRDTMVTKLHSQ-IRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHT 824
            E+      K   Q +RQ +   +E   Q Q            +AE   + + A  +    
Sbjct: 1697 EREARRRGKAEEQAVRQRELAEQELEKQRQ------------LAEGTAQQRLAAEQ---- 1740

Query: 825  ELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTK---EVEMMK 881
                 ++ +  + +E  +QQ + L  +L  L        ++ Q   ++  K   E+E++ 
Sbjct: 1741 -----ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1795

Query: 882  AAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQL 941
            A+  +  E++RS   +  QRL+    R  EL    A+   L  E K+       +   + 
Sbjct: 1796 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ------RQLAEE 1849

Query: 942  QAAESRYEAQKRITQVFELEILDLYGRL--EKDGLLKKLEEEKAEAAEAAEE 991
             AA  R EA++ + +  +L  +    RL  E +  LK+ E E       AE+
Sbjct: 1850 DAARQRAEAERVLAE--KLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1899



 Score = 33.9 bits (76), Expect = 0.93
 Identities = 49/269 (18%), Positives = 108/269 (40%), Gaps = 52/269 (19%)

Query: 743  QEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED 802
            ++ +++ W+  + +   R+  +  Q D    +L    RQL++ RE     +  L   L+D
Sbjct: 1197 RDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE----SADPLGAWLQD 1252

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
             R    +++                    +  L++S++V++Q+    RQ   L E  E +
Sbjct: 1253 ARRRQEQIQ--------------------AMPLADSQAVREQL----RQEQALLEEIERH 1288

Query: 863  LEQLQ------NKHSDTTKEVEMMKAAYRKELE------------KNRSHVLQQTQRLDT 904
             E+++       ++ +  K+ E+    Y+ +LE                 V+Q+   L T
Sbjct: 1289 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1348

Query: 905  SQKRILELESH----LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL 960
                +  L S     +++    + E+++  E  + + R +L   E+  E Q+++ +    
Sbjct: 1349 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ 1408

Query: 961  EILDLYGRLEKDGLLKKLEEEKAEAAEAA 989
                     E   L ++++EE     EAA
Sbjct: 1409 --AKAQAEREAKELQQRMQEEVVRREEAA 1435


>gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-like
            protein 2 isoform 3 [Homo sapiens]
          Length = 595

 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 75/344 (21%), Positives = 148/344 (43%), Gaps = 31/344 (9%)

Query: 724  IKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTK---LHSQIR 780
            +K + L+    ++K Q K  E  ++  K +  + Q    +L+ Q  T++ +   L++ + 
Sbjct: 83   VKISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLY 142

Query: 781  QLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSES 840
             ++     F  +S++L  +L+       + + EL++A + V  TE   +      S + +
Sbjct: 143  HMERSLRYFEEESKDLAVRLQHS----LQCKGELERALSAVIATEKKKANQLSSCSKAHT 198

Query: 841  VQQQMEFLNRQLLVLGEVNELY--LEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQ 898
              +  + L  Q L+  ++ +L    +QLQ +  +  + +E  +A + + + K    +   
Sbjct: 199  EWELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTL 258

Query: 899  TQRLDTSQKRILELESHLAKKDHLLLEQ-----KKYLEDVKLQ-ARGQLQAAESRYEAQK 952
             +      +R+ ELE  L+K  + + E           +V+LQ  R +L+      ++Q 
Sbjct: 259  KKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQV 318

Query: 953  RITQVFELEILDLYGRL-EKDGLLKKLEEEKAEAAEAAEERL-------DCCNDGCS--- 1001
            +  Q   L       R+ E++  L+K EE   E  E   +         +  N+  S   
Sbjct: 319  KNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQ 378

Query: 1002 -DSMVGHNEEASGHNGETKTP---RPSSARGSSGSRGGGGSSSS 1041
             +  V   +E  G   ET+T     P +ARG  G+ G GG SSS
Sbjct: 379  LEQQVKELQEKLGEVKETETSAQKEPEAARGP-GAPGPGGESSS 421



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 50/236 (21%), Positives = 103/236 (43%), Gaps = 33/236 (13%)

Query: 709 RQQHALRNRRLLRKVIKAAALEEHNAA----------MKDQLKLQEKDIQMWKVSLQKEQ 758
           R QH+L+ +  L + + A    E   A           + +L+   +D  + K  L + +
Sbjct: 161 RLQHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLK 220

Query: 759 ARYNQLQEQRD--------------TMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCR 804
             + QLQ +RD                ++K+  +I  L+ ++++   + +EL+  L   +
Sbjct: 221 ESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQQDMRRVEELERSLSKLK 280

Query: 805 NMIAE-LRIELKKANNKV--CHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNEL 861
           N +AE L  E     ++V   H    L +V+ +L +     Q +  LNR+        E 
Sbjct: 281 NQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEE 340

Query: 862 YL----EQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELE 913
            L    E+LQ +H +  +++   ++ + +EL       LQ  Q++   Q+++ E++
Sbjct: 341 RLRKQEERLQEQH-EKLRQLAKPQSVF-EELNNENKSTLQLEQQVKELQEKLGEVK 394


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 63/280 (22%), Positives = 121/280 (43%), Gaps = 32/280 (11%)

Query: 753  SLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRI 812
            SL+ E  +    Q          H+  +Q + +R+      +EL+TKL       ++L++
Sbjct: 603  SLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKV 662

Query: 813  ELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSD 872
             +    ++    +L+  ++ +K SNS  ++ +M     QLL L +  E   E++    S 
Sbjct: 663  NMA---HRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLE---EKIVAYSSI 716

Query: 873  TTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLED 932
              K  E+      +EL +    +      ++T  ++I  L    AKK H  LEQ K +E 
Sbjct: 717  AAKNAEL-----EQELMEKNEKIRSLETNINTEHEKIC-LAFEKAKKIH--LEQHKEMEK 768

Query: 933  VKLQARGQLQAAESRYEAQKRITQVFELEI------LDLYGRL--EKDGLLKKLEEEKAE 984
               +   QL+  + +++ Q++   + + +I      L+   RL  E  G +KK   +K E
Sbjct: 769  QIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDE 828

Query: 985  AAEAAE----------ERLDCCNDGCSDSMVGHNEEASGH 1014
            A +A +           +LD   + C + +V H  +  G+
Sbjct: 829  ALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGN 868



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 91/411 (22%), Positives = 165/411 (40%), Gaps = 53/411 (12%)

Query: 629  KKAKGNTEEDGVPSTSPMEVLDRLIQQGADAHSKELNK----LPLPSKSVDWTHFGGSPP 684
            +K     ++D +     +E LDRL+ +      KE  K    L      V          
Sbjct: 788  EKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQL 847

Query: 685  SDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAA-MKDQLKLQ 743
               +   +++L+L  NQL   + K ++   +    +  + K   ++ H+     +Q  + 
Sbjct: 848  DSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVIL 907

Query: 744  EKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLED- 802
            +  +Q  +  LQ+E  R  +L++ +    TKL  Q+ +L+ + ++    S E   K+E+ 
Sbjct: 908  QHTLQQQQQMLQQETIRNGELEDTQ----TKLEKQVSKLEQELQKQRESSAEKLRKMEEK 963

Query: 803  CRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELY 862
            C +   E  ++ +K          +  ++ Q       +++++  L R     GE   ++
Sbjct: 964  CESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRD----GENKAMH 1019

Query: 863  LEQLQ----------NKHSDTTKEVEMMKAAYRKEL------------EKNRSH-----V 895
            L QL            K ++  KE+E ++ +   EL            E   +H      
Sbjct: 1020 LSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKST 1079

Query: 896  LQQTQRL-DTSQKRILELESHLAKKDHL---LLEQKKYLEDVKLQARGQLQAAESR-YEA 950
            L+Q Q L D  QK  L LE        L   L E K  +ED K +     QA + R +E 
Sbjct: 1080 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL 1139

Query: 951  QKRITQVFELE--ILDLYGRLEK-----DGLLKKLEEEKAEAAEAAEERLD 994
            ++R  QV  L+  I +  G +E+     +G L+K E E  E  +  E   D
Sbjct: 1140 KQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLND 1190



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 63/283 (22%), Positives = 126/283 (44%), Gaps = 27/283 (9%)

Query: 693  DQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQE--KDIQMW 750
            DQ L   N  L +R  +  H     R  R  ++   ++      K +L+L+E  K I+  
Sbjct: 1129 DQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESL 1188

Query: 751  KVSLQ--KEQARYNQ-LQEQRDTMVTKLHSQIRQLQHDREEFYN----QSQELQTKLEDC 803
               LQ  KEQ R  + +  Q +  +++L  +I + Q   +E  +    Q Q + T+ ++ 
Sbjct: 1189 NDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEA 1248

Query: 804  RNMIAELRIELKKANNKVCHTELL------------LSQVSQKLSNSESVQQQMEFLNRQ 851
             ++  ELR+  ++  N   HTEL             + ++S +L + + + ++ +     
Sbjct: 1249 IDLGQELRLTREQVQNS--HTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNH 1306

Query: 852  L---LVLGEVNELYLE-QLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQK 907
            L   L   +V E +LE ++Q +    + EVE +K AY  E+  ++ +  +     D+ + 
Sbjct: 1307 LAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKS 1366

Query: 908  RILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEA 950
             + +L   L K    L E +  + ++  Q + + +  E+  EA
Sbjct: 1367 SVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEA 1409



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 83/393 (21%), Positives = 164/393 (41%), Gaps = 67/393 (17%)

Query: 639 GVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSD-EIRTLRDQL-- 695
           G+ + SP E + ++     D   K  +K+           F  S P D EI++LR++L  
Sbjct: 192 GLLNYSPYENVCKISGSSTDFQKKPRDKM-----------FSSSAPVDQEIKSLREKLNK 240

Query: 696 -------LLLHNQLLYERFKRQQHALRNRRLLRKVIKAAA--------LEEHNAAMKDQL 740
                  L+  N  L  +F+     L   R    ++++A         LEE    ++ ++
Sbjct: 241 LRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIINLEAEV 300

Query: 741 KLQEKDI--------QMWKVSLQKEQARYNQLQEQRDTMVTKLHS--QIRQLQHDREEFY 790
             Q+K +        Q  K+ ++KEQ+     +E     V  L    Q ++ +  R E  
Sbjct: 301 SAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEAL 360

Query: 791 NQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNR 850
             ++EL    +  +  +AE ++E  +A  ++    L   +   K      +Q++      
Sbjct: 361 YNAEELSKAFQQYKKKVAE-KLEKVQAEEEILERNLTNCEKENK-----RLQERCGLYKS 414

Query: 851 QLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRIL 910
           +L +L E     L QL+ ++++  +++ +M         KN   + Q T+    S++ IL
Sbjct: 415 ELEILKEK----LRQLKEENNNGKEKLRIMAV-------KNSEVMAQLTE----SRQSIL 459

Query: 911 ELESHLAKKDHLLLEQKKYLED-----VKLQARGQ-LQAAESRYEAQKRITQVFELEILD 964
           +LES L  KD +L ++   + +     V++ A+ + L   +   E+ +   +  E  I  
Sbjct: 460 KLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQ 519

Query: 965 LYGRLEKDGLLKKLEEEKAEAAEAAEER-LDCC 996
           L  + E  G    L + +  +    E+R + CC
Sbjct: 520 LPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCC 552



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 62/275 (22%), Positives = 122/275 (44%), Gaps = 25/275 (9%)

Query: 729  LEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREE 788
            LE+   A+K+  KLQ         +LQK +    +LQ        +L S +RQLQ  R+ 
Sbjct: 1034 LEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHG----ELKSTLRQLQELRDV 1089

Query: 789  FYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLS--NSESVQQQME 846
                 Q+ Q  LE+    I +L  EL++   ++   +  L ++ Q L   N E  Q+  +
Sbjct: 1090 L----QKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQ 1145

Query: 847  FLNRQLLV---LGEVN------ELYLEQLQNKHSDTTKEVEMMKAAY---RKELEKNRSH 894
              +  + +    GE+       E  LE+ + +  +  K++E +       +++L +    
Sbjct: 1146 VTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFI 1205

Query: 895  VLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQA--RGQLQAAESRYEAQK 952
            +LQ  Q +   +K I   +  + + + ++ EQ++Y+     +A   GQ +   +R + Q 
Sbjct: 1206 MLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQ-ELRLTREQVQN 1264

Query: 953  RITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAE 987
              T++ E     +  + E + L  +LE+ K  + E
Sbjct: 1265 SHTELAEARHQQVQAQREIERLSSELEDMKQLSKE 1299



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 64/290 (22%), Positives = 123/290 (42%), Gaps = 51/290 (17%)

Query: 704 YERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQ 763
           YE+ +RQ+       L  K+I+   +E  N+ +K  +  +    Q+ +  L ++ +  ++
Sbjct: 632 YEK-ERQRLVTGIEELRTKLIQ---IEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSK 687

Query: 764 LQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCH 823
           L+ +    +TK  SQ+  L+   EE       +  K        AEL  EL + N K+  
Sbjct: 688 LESE----MTKKCSQLLTLEKQLEEKIVAYSSIAAKN-------AELEQELMEKNEKIRS 736

Query: 824 TELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAA 883
            E  ++   +K+                 L   +  +++LEQ    H +  K++E ++A 
Sbjct: 737 LETNINTEHEKIC----------------LAFEKAKKIHLEQ----HKEMEKQIERLEA- 775

Query: 884 YRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQA 943
              +LEK      +Q + +   Q+ I+  + HL   D LL E K  ++   ++    L+A
Sbjct: 776 ---QLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKA 832

Query: 944 AESRYEAQ----KRITQVFE-------LEILDLYGRLEK-DGLLKKLEEE 981
            +++   +    +++    E       L +  L G  EK +  LKK  EE
Sbjct: 833 LQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEE 882


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,942,739
Number of Sequences: 37866
Number of extensions: 2732421
Number of successful extensions: 18451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 1027
Number of HSP's that attempted gapping in prelim test: 13504
Number of HSP's gapped (non-prelim): 4547
length of query: 1164
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1051
effective length of database: 13,968,660
effective search space: 14681061660
effective search space used: 14681061660
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.