BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sapiens] (1174 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sa... 2370 0.0 gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo s... 767 0.0 gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo s... 746 0.0 gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens] 383 e-106 gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapi... 378 e-104 gi|55770862 thyroglobulin [Homo sapiens] 35 0.42 gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 33 2.1 gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 32 3.6 gi|171906593 branched chain ketoacid dehydrogenase kinase isofor... 32 4.6 gi|171906589 branched chain ketoacid dehydrogenase kinase isofor... 32 4.6 gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens] 32 4.6 >gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sapiens] Length = 1174 Score = 2370 bits (6143), Expect = 0.0 Identities = 1174/1174 (100%), Positives = 1174/1174 (100%) Query: 1 MYDADEDMQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVE 60 MYDADEDMQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVE Sbjct: 1 MYDADEDMQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVE 60 Query: 61 DAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTY 120 DAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTY Sbjct: 61 DAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTY 120 Query: 121 SAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLD 180 SAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLD Sbjct: 121 SAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLD 180 Query: 181 PGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSML 240 PGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSML Sbjct: 181 PGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSML 240 Query: 241 ARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEM 300 ARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEM Sbjct: 241 ARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEM 300 Query: 301 VKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETK 360 VKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETK Sbjct: 301 VKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETK 360 Query: 361 KAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQ 420 KAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQ Sbjct: 361 KAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQ 420 Query: 421 KFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLS 480 KFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLS Sbjct: 421 KFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLS 480 Query: 481 HLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSP 540 HLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSP Sbjct: 481 HLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSP 540 Query: 541 ILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSE 600 ILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSE Sbjct: 541 ILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSE 600 Query: 601 VSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASG 660 VSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASG Sbjct: 601 VSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASG 660 Query: 661 VVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSP 720 VVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSP Sbjct: 661 VVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSP 720 Query: 721 RNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIV 780 RNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIV Sbjct: 721 RNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIV 780 Query: 781 AIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGM 840 AIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGM Sbjct: 781 AIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGM 840 Query: 841 RHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSE 900 RHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSE Sbjct: 841 RHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSE 900 Query: 901 TGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEG 960 TGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEG Sbjct: 901 TGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEG 960 Query: 961 ITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGY 1020 ITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGY Sbjct: 961 ITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGY 1020 Query: 1021 HLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSR 1080 HLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSR Sbjct: 1021 HLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSR 1080 Query: 1081 DGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGC 1140 DGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGC Sbjct: 1081 DGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGC 1140 Query: 1141 RNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV 1174 RNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV Sbjct: 1141 RNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV 1174 >gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo sapiens] Length = 1133 Score = 767 bits (1981), Expect = 0.0 Identities = 447/1164 (38%), Positives = 688/1164 (59%), Gaps = 77/1164 (6%) Query: 24 EACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQAEAQHASGEVEEPPR 83 E W ++ ++ KGLV+Q +DSF+ FI + +++I++ + A+ P Sbjct: 24 EEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDAD-----------PM 72 Query: 84 YLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQ 143 + LK+ IY+ P E P+ P+E RLR++TYSAP+ VDI T G +++ Sbjct: 73 WYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT---RGSQRIIRN 129 Query: 144 HQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATN 203 IG++PIMLRS+ C+L G T + +LNECPLDPGGYFI+ G EKV++ QE+++ N Sbjct: 130 ALP--IGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKN 187 Query: 204 TVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYI 263 + V A D K A S T+ M + G R + Sbjct: 188 RIIVEA--DRKGAVGASVTSSTHEKKSRTN-----MAVKQG----------RFYLRHNTL 230 Query: 264 KQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQ--EQNVALNFI 321 +++PI+I+F+A+G SD++I++ I + +M PSL+E Q Q AL +I Sbjct: 231 SEDIPIVIIFKAMGVESDQEIVQMI---GTEEHVMAAFGPSLEECQKAQIFTQMQALKYI 287 Query: 322 GSRGAKP----GVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAAL 377 G++ + G K+ +I+ A+E+L +L HV V +F K + MV R++LA Sbjct: 288 GNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQ- 346 Query: 378 GRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFI--DRGKDFNLELAI 435 G ++DDRD+YGNKRL+LAG LL+ LF +FK E++ A + I R F++ + Sbjct: 347 GDNKVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHM 406 Query: 436 KTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKL 495 + I++G+ +++TGNW K+ R GV+QVL+RL++ S L + R++S + K+ Sbjct: 407 RQDQITNGMVNAISTGNWS-LKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKV 465 Query: 496 AKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEE 555 + PR L + WGM+CP++TPEG A GLVKNLALM +I+ + PI++ +E++ Sbjct: 466 SGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNL 525 Query: 556 ISPAAIA--DATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIR 613 + ++ + +F+NG +G+ +D ++L+NT R +RR I VS+ ++ +R + Sbjct: 526 LCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRA-GYINEFVSISTNLTDRCVY 584 Query: 614 IYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETV 673 I +D GR+CRP +IV+KQK + +H+++L + Y N+ +D + +VEY+D EE Sbjct: 585 ISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQG-YRNF--EDFLHESLVEYLDVNEENDC 641 Query: 674 MLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAM 733 +A+ + + TH EI P +LGVCA +IP+P HNQSPRNTYQ AMGKQAM Sbjct: 642 NIALYEHTINKDT-------THLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAM 694 Query: 734 GVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDS 793 G N R+DTL ++L YPQKP+V T+++E + F +LPAG N+ VA+ SY+GY+ ED+ Sbjct: 695 GTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDA 754 Query: 794 VIMNRSAVDRGFFRSVFYRSYK---EQESKKGFDQ--EEVFEKPTRETCQGMRHAIYDKL 848 +++N++++DRGF R + Y++ K ++ + + FD+ + + TR+ RH I L Sbjct: 755 LVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPI--WRHEI---L 809 Query: 849 DDDGLIAPGVRVSGDDVIIGKTV-TLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQV 907 D DG+ +PG +V V++ K++ T+ + E + ++ +D + + +++V Sbjct: 810 DADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKV 869 Query: 908 MVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIII 967 M++ N E K+ +R R P+IGDKF+SRHGQKG CG+ QEDMPF GI PDII+ Sbjct: 870 MISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIM 929 Query: 968 NPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEV 1027 NPH PSRMT+G LIE L GK G T F + V+ + L +GY+ G + Sbjct: 930 NPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGS-KVKDVCEDLVRHGYNYLGKDY 988 Query: 1028 LYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFG 1087 + +G TG + + I+ GP YYQ+LKHMV DK+H+RARGP +L RQP EGRSRDGGLR G Sbjct: 989 VTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLG 1048 Query: 1088 EMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQIS 1147 EMERDC I +GA+ L ERL +SD ++V VC CG++ + C C++ +S Sbjct: 1049 EMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGW------CHYCKSSCHVS 1102 Query: 1148 LVRMPYACKLLFQELMSMSIAPRM 1171 +R+PYACKLLFQEL SM+I PR+ Sbjct: 1103 SLRIPYACKLLFQELQSMNIIPRL 1126 >gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo sapiens] Length = 1075 Score = 746 bits (1925), Expect = 0.0 Identities = 433/1106 (39%), Positives = 659/1106 (59%), Gaps = 66/1106 (5%) Query: 82 PRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQ 141 P + LK+ IY+ P E P+ P+E RLR++TYSAP+ VDI T G +++ Sbjct: 13 PMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT---RGSQRII 69 Query: 142 TQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMA 201 IG++PIMLRS+ C+L G T + +LNECPLDPGGYFI+ G EKV++ QE+++ Sbjct: 70 RNALP--IGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLS 127 Query: 202 TNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLP 261 N + V A D K A S T+ M + G R Sbjct: 128 KNRIIVEA--DRKGAVGASVTSSTHEKKSRTN-----MAVKQG----------RFYLRHN 170 Query: 262 YIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQ--EQNVALN 319 + +++PI+I+F+A+G SD++I++ I + +M PSL+E Q Q AL Sbjct: 171 TLSEDIPIVIIFKAMGVESDQEIVQMI---GTEEHVMAAFGPSLEECQKAQIFTQMQALK 227 Query: 320 FIGSRGAKP----GVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLA 375 +IG++ + G K+ +I+ A+E+L +L HV V +F K + MV R++LA Sbjct: 228 YIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILA 287 Query: 376 ALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFI--DRGKDFNLEL 433 G ++DDRD+YGNKRL+LAG LL+ LF +FK E++ A + I R F++ Sbjct: 288 Q-GDNKVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVK 346 Query: 434 AIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDG 493 ++ I++G+ +++TGNW K+ R GV+QVL+RL++ S L + R++S + Sbjct: 347 HMRQDQITNGMVNAISTGNWS-LKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTR 405 Query: 494 KLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENL 553 K++ PR L + WGM+CP++TPEG A GLVKNLALM +I+ + PI++ +E++ Sbjct: 406 KVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDV 465 Query: 554 EEISPAAIA--DATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIRERE 611 + ++ + +F+NG +G+ +D ++L+NT R +RR I VS+ ++ +R Sbjct: 466 NLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRA-GYINEFVSISTNLTDRC 524 Query: 612 IRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEE 671 + I +D GR+CRP +IV+KQK + +H+++L + Y N+ +D + +VEY+D EE Sbjct: 525 VYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQG-YRNF--EDFLHESLVEYLDVNEEN 581 Query: 672 TVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQ 731 +A+ + + TH EI P +LGVCA +IP+P HNQSPRNTYQ AMGKQ Sbjct: 582 DCNIALYEHTINKDT-------THLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQ 634 Query: 732 AMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQE 791 AMG N R+DTL ++L YPQKP+V T+++E + F +LPAG N+ VA+ SY+GY+ E Sbjct: 635 AMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIE 694 Query: 792 DSVIMNRSAVDRGFFRSVFYRSYK---EQESKKGFDQ--EEVFEKPTRETCQGMRHAIYD 846 D++++N++++DRGF R + Y++ K ++ + + FD+ + + TR+ RH I Sbjct: 695 DALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPI--WRHEI-- 750 Query: 847 KLDDDGLIAPGVRVSGDDVIIGKTV-TLPENEDELESTNRRYTKRDCSTFLRTSETGIVD 905 LD DG+ +PG +V V++ K++ T+ + E + ++ +D + + ++ Sbjct: 751 -LDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIE 809 Query: 906 QVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDI 965 +VM++ N E K+ +R R P+IGDKF+SRHGQKG CG+ QEDMPF GI PDI Sbjct: 810 KVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDI 869 Query: 966 IINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGN 1025 I+NPH PSRMT+G LIE L GK G T F + V+ + L +GY+ G Sbjct: 870 IMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGS-KVKDVCEDLVRHGYNYLGK 928 Query: 1026 EVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLR 1085 + + +G TG + + I+ GP YYQ+LKHMV DK+H+RARGP +L RQP EGRSRDGGLR Sbjct: 929 DYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLR 988 Query: 1086 FGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQ 1145 GEMERDC I +GA+ L ERL +SD ++V VC CG++ + C C++ Sbjct: 989 LGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGW------CHYCKSSCH 1042 Query: 1146 ISLVRMPYACKLLFQELMSMSIAPRM 1171 +S +R+PYACKLLFQEL SM+I PR+ Sbjct: 1043 VSSLRIPYACKLLFQELQSMNIIPRL 1068 >gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens] Length = 1135 Score = 383 bits (983), Expect = e-106 Identities = 330/1116 (29%), Positives = 492/1116 (44%), Gaps = 137/1116 (12%) Query: 110 PNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDR 169 P E R R TY L DI V + K F+G +PIM++S C L L + Sbjct: 100 PAECRGRRSTYRGKLTADINWAV-----NGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQ 154 Query: 170 DLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSK-----YAYTGECRSC 224 L E +E + GGYFIING EKV+ N + K Y G C Sbjct: 155 ALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHC 214 Query: 225 LENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQE--VPIIIVFRALGFVSDR 282 + + + + L G ++ Y K+ +P+ +AL SD Sbjct: 215 VREEHSAVN-MNLHYLENG-----------TVMLNFIYRKELFFLPLGFALKALVSFSDY 262 Query: 283 DILEHIIYDFEDPEMM-----EMVKPSLDEAFVIQEQNVALNFIGSR-GAKPGVTKEKRI 336 I + +I ED + +M++ ++E Q+Q LN++G K V Sbjct: 263 QIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQ--VLNYLGECFRVKLNVPDWYPN 320 Query: 337 KYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLA 396 + A E L + + + T+K Y L M +L A G D+ D N+ + Sbjct: 321 EQAAEFLFNQC---ICIHLKSNTEKFYMLCLMTRKLFALAKGECMEDNPDSLVNQEVLTP 377 Query: 397 GPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGL------KYSLAT 450 G L + + L ++I K + ++ RI + G+ +Y AT Sbjct: 378 GQLFLMFLKEKLEGWLVSIKIAFDKKAQK-TSVSMNTDNLMRIFTMGIDLTKPFEYLFAT 436 Query: 451 GNWGDQKKAHQAR-AGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPR-----QLHNT 504 GN + + +G+ V ++L F LSH R ++ R AK R +L Sbjct: 437 GNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVH----RGADFAKMRTTTVRRLLPE 492 Query: 505 LWGMVCPAETPEGHAVGLVKNL-ALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIAD 563 WG +CP TP+G GL+ +L A+ ++ + I L + ++ + ++ Sbjct: 493 SWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPIDGAPHRSYSE 552 Query: 564 ATKIFVNGCWVG-IHKD-PEQLMNTLRK---LRRQMDIIVSEVSMIRDIREREIR----I 614 + ++G VG + KD + ++LR LR + EV +I + + + Sbjct: 553 CYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTGKPSLYPGLFL 612 Query: 615 YTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVM 674 +T R+ RP+ Q L L K E I T+E+ + Sbjct: 613 FTTPCRLVRPV-----QNLALGKE------------------------ELIGTMEQIFMN 643 Query: 675 LAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMG 734 +A+ D++ + TH E+ P +L V A+ IPF DHNQSPRN YQ MGKQ MG Sbjct: 644 VAIFEDEV------FAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMG 697 Query: 735 VYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSV 794 + + R D + L PQ PLV +Y P G N+IVA+ SYTGY+ ED++ Sbjct: 698 FPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAM 757 Query: 795 IMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHA---IYDKLDDD 851 I+N+++ +RGF Y+S + D E ++ G++ + KLDDD Sbjct: 758 IVNKASWERGFAHGSVYKS-------EFIDLSEKIKQGDSSLVFGIKPGDPRVLQKLDDD 810 Query: 852 GLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQVMVTL 911 GL G ++ + D S T + ++ E +VD + V Sbjct: 811 GLPFIGAKL--------------QYGDPYYSYLNLNTGESFVMYYKSKENCVVDNIKVCS 856 Query: 912 NQEG---YKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIIN 968 N G +K I +R R P IGDKFASRHGQKG + EDMPFT G+ PDI+ N Sbjct: 857 NDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFN 916 Query: 969 PHAIPSRMTIGHLIECLQGKVSANKGEIGDATPF---NDAVNVQKISNLLSDYGYHLRGN 1025 PH PSRMTIG LIE + GK +A G DATPF + ++ +L GY+ G Sbjct: 917 PHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGT 976 Query: 1026 EVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLR 1085 E LY+G +G ++ + IFIG YYQRL+HMV DK R G + QP+ GR+ GG+R Sbjct: 977 ERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIR 1036 Query: 1086 FGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIM----------AIANTRTHTY 1135 FGEMERD +AHG + L +RLF SD HVC CG + + + R Y Sbjct: 1037 FGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKY 1096 Query: 1136 ECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRM 1171 C C I V +PY + EL +M+I ++ Sbjct: 1097 NCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKL 1132 >gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapiens] Length = 1079 Score = 378 bits (971), Expect = e-104 Identities = 320/1080 (29%), Positives = 481/1080 (44%), Gaps = 132/1080 (12%) Query: 146 KTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTV 205 K F+G +PIM++S C L L + L E +E + GGYFIING EKV+ N Sbjct: 75 KQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFP 134 Query: 206 YVFAKKDSK-----YAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATL 260 + K Y G C+ + + + L G ++ Sbjct: 135 IAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVN-MNLHYLENG-----------TVMLNF 182 Query: 261 PYIKQE--VPIIIVFRALGFVSDRDILEHIIYDFEDPEMM-----EMVKPSLDEAFVIQE 313 Y K+ +P+ +AL SD I + +I ED + +M++ ++E Q+ Sbjct: 183 IYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQK 242 Query: 314 QNVALNFIGSR-GAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRL 372 Q LN++G K V + A E L + + + T+K Y L M +L Sbjct: 243 Q--VLNYLGECFRVKLNVPDWYPNEQAAEFLFNQC---ICIHLKSNTEKFYMLCLMTRKL 297 Query: 373 LLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLE 432 A G D+ D N+ + G L + + L ++I K + ++ Sbjct: 298 FALAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQK-TSVSMN 356 Query: 433 LAIKTRIISDGL------KYSLATGNWGDQKKAHQAR-AGVSQVLNRLTFASTLSHLRRL 485 RI + G+ +Y ATGN + + +G+ V ++L F LSH R + Sbjct: 357 TDNLMRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCV 416 Query: 486 NSPIGRDGKLAKPR-----QLHNTLWGMVCPAETPEGHAVGLVKNL-ALMAYISVGSQPS 539 + R AK R +L WG +CP TP+G GL+ +L A+ ++ + Sbjct: 417 H----RGADFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTA 472 Query: 540 PILEFLEEWSMENLEEISPAAIADATKIFVNGCWVG-IHKD-PEQLMNTLRK---LRRQM 594 I L + ++ + ++ + ++G VG + KD + ++LR LR + Sbjct: 473 SIPALLCNLGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKR 532 Query: 595 DIIVSEVSMIRDIREREIR----IYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNN 650 EV +I + + ++T R+ RP+ Q L L K Sbjct: 533 IPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRPV-----QNLALGKE------------ 575 Query: 651 YSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASI 710 E I T+E+ + +A+ D++ + TH E+ P +L V A+ Sbjct: 576 ------------ELIGTMEQIFMNVAIFEDEV------FAGVTTHQELFPHSLLSVIANF 617 Query: 711 IPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFR 770 IPF DHNQSPRN YQ MGKQ MG + + R D + L PQ PLV +Y Sbjct: 618 IPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMD 677 Query: 771 ELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFE 830 P G N+IVA+ SYTGY+ ED++I+N+++ +RGF Y+S + D E + Sbjct: 678 NYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKS-------EFIDLSEKIK 730 Query: 831 KPTRETCQGMRHA---IYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRY 887 + G++ + KLDDDGL G ++ + D S Sbjct: 731 QGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKL--------------QYGDPYYSYLNLN 776 Query: 888 TKRDCSTFLRTSETGIVDQVMVTLNQEG---YKFCKIRVRSVRIPQIGDKFASRHGQKGT 944 T + ++ E +VD + V N G +K I +R R P IGDKFASRHGQKG Sbjct: 777 TGESFVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGI 836 Query: 945 CGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPF-- 1002 + EDMPFT G+ PDI+ NPH PSRMTIG LIE + GK +A G DATPF Sbjct: 837 LSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIF 896 Query: 1003 -NDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHS 1061 + ++ +L GY+ G E LY+G +G ++ + IFIG YYQRL+HMV DK Sbjct: 897 SEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQV 956 Query: 1062 RARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNL 1121 R G + QP+ GR+ GG+RFGEMERD +AHG + L +RLF SD HVC Sbjct: 957 RTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVK 1016 Query: 1122 CGIM----------AIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRM 1171 CG + + + R Y C C I V +PY + EL +M+I ++ Sbjct: 1017 CGSLLSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKL 1076 >gi|55770862 thyroglobulin [Homo sapiens] Length = 2768 Score = 35.0 bits (79), Expect = 0.42 Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 13/125 (10%) Query: 88 FEQIYLSKPTHW---------ERDGAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEE 138 F+Q+YL K + +D P P P EA L +S VD+ + ++ G + Sbjct: 1815 FQQVYLWKDSDMGSRPESMGCRKDTVPRPASPTEAGLTTELFSP---VDLNQVIVN-GNQ 1870 Query: 139 QLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQE 198 L +Q F + +CL + + C+L E YF + + + Sbjct: 1871 SLSSQKHWLFKHLFSAQQANLWCLSRCVQEHSFCQLAEITESASLYFTCTLYPEAQVCDD 1930 Query: 199 KMATN 203 M +N Sbjct: 1931 IMESN 1935 >gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] Length = 4624 Score = 32.7 bits (73), Expect = 2.1 Identities = 19/78 (24%), Positives = 41/78 (52%), Gaps = 3/78 (3%) Query: 581 EQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHI 640 E+ L + + +D I ++ +++IRE +I I G I ++ + LL+ + I Sbjct: 1237 EEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEI 1296 Query: 641 DQLKEREYNNYSWQDLVA 658 D++ + +Y+W+ L+A Sbjct: 1297 DKV---DTLHYAWEKLLA 1311 >gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] Length = 4024 Score = 32.0 bits (71), Expect = 3.6 Identities = 11/53 (20%), Positives = 33/53 (62%) Query: 35 DEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQAEAQHASGEVEEPPRYLLK 87 + + +++++++ + E +++ +R VE+ Q+E ++ G++++ RYL K Sbjct: 669 EHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKK 721 >gi|171906593 branched chain ketoacid dehydrogenase kinase isoform b [Homo sapiens] Length = 365 Score = 31.6 bits (70), Expect = 4.6 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 31/197 (15%) Query: 181 PGGYFIIN---GSEKVLIAQEKMATNTVYV-FAKKDSKYAYTGECRSCLENSS-RPTSTI 235 PGG + G L A+ AT+T +V A++ SK + +S ++ ++ +P+ + Sbjct: 11 PGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRL 70 Query: 236 WVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGF------VSDRDILEHI- 288 +M+ G +S G ++ + Y++QE+P+ I R GF + + H+ Sbjct: 71 TPTMMLYAG----RSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVH 126 Query: 289 ---IYDFEDPEMMEMVKPSLDEAFVIQ---------EQNVALNFIGSRGAKPGVTKEKRI 336 I F+ +K DEA Q + V L G R ++ + EK + Sbjct: 127 ELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLV 186 Query: 337 KYAKEVLQKEMLPHVGV 353 +Y L K + +G+ Sbjct: 187 RY---FLDKTLTSRLGI 200 >gi|171906589 branched chain ketoacid dehydrogenase kinase isoform a [Homo sapiens] Length = 412 Score = 31.6 bits (70), Expect = 4.6 Identities = 45/197 (22%), Positives = 84/197 (42%), Gaps = 31/197 (15%) Query: 181 PGGYFIIN---GSEKVLIAQEKMATNTVYV-FAKKDSKYAYTGECRSCLENSS-RPTSTI 235 PGG + G L A+ AT+T +V A++ SK + +S ++ ++ +P+ + Sbjct: 11 PGGGLPLRPLLGPALALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRL 70 Query: 236 WVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGF------VSDRDILEHI- 288 +M+ G +S G ++ + Y++QE+P+ I R GF + + H+ Sbjct: 71 TPTMMLYAG----RSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVH 126 Query: 289 ---IYDFEDPEMMEMVKPSLDEAFVIQ---------EQNVALNFIGSRGAKPGVTKEKRI 336 I F+ +K DEA Q + V L G R ++ + EK + Sbjct: 127 ELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLV 186 Query: 337 KYAKEVLQKEMLPHVGV 353 +Y L K + +G+ Sbjct: 187 RY---FLDKTLTSRLGI 200 >gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens] Length = 822 Score = 31.6 bits (70), Expect = 4.6 Identities = 20/67 (29%), Positives = 35/67 (52%) Query: 800 AVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYDKLDDDGLIAPGVR 859 AVDR R V K+++ KKG +E+ +K T ++Y +L ++GL+ ++ Sbjct: 454 AVDRERERPVKAGKKKDKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEEGLLIQALK 513 Query: 860 VSGDDVI 866 V+ D I Sbjct: 514 VNLSDYI 520 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 44,004,339 Number of Sequences: 37866 Number of extensions: 1985852 Number of successful extensions: 4479 Number of sequences better than 10.0: 11 Number of HSP's better than 10.0 without gapping: 7 Number of HSP's successfully gapped in prelim test: 4 Number of HSP's that attempted gapping in prelim test: 4425 Number of HSP's gapped (non-prelim): 19 length of query: 1174 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1061 effective length of database: 13,968,660 effective search space: 14820748260 effective search space used: 14820748260 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.