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Search of human proteins with 4505293
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505293 MYB-related protein B [Homo sapiens]
(700 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505293 MYB-related protein B [Homo sapiens] 1422 0.0
gi|122937231 v-myb myeloblastosis viral oncogene homolog (avian)... 466 e-131
gi|221139773 v-myb myeloblastosis viral oncogene homolog (avian)... 452 e-127
gi|239735492 v-myb myeloblastosis viral oncogene homolog isoform... 405 e-113
gi|239735488 v-myb myeloblastosis viral oncogene homolog isoform... 403 e-112
gi|194328729 v-myb myeloblastosis viral oncogene homolog isoform... 402 e-112
gi|46361980 v-myb myeloblastosis viral oncogene homolog isoform ... 371 e-102
gi|239735494 v-myb myeloblastosis viral oncogene homolog isoform... 368 e-102
gi|239735496 v-myb myeloblastosis viral oncogene homolog isoform... 284 2e-76
gi|239735490 v-myb myeloblastosis viral oncogene homolog isoform... 283 4e-76
gi|194328727 v-myb myeloblastosis viral oncogene homolog isoform... 283 4e-76
gi|92859678 small nuclear RNA activating complex, polypeptide 4,... 97 5e-20
gi|11067747 CDC5-like [Homo sapiens] 72 2e-12
gi|215599992 cyclin D binding myb-like transcription factor 1 is... 49 1e-05
gi|215599981 cyclin D binding myb-like transcription factor 1 is... 49 1e-05
gi|215599967 cyclin D binding myb-like transcription factor 1 is... 49 1e-05
gi|91982772 mucin 17 [Homo sapiens] 43 9e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 42 0.002
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 42 0.002
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 42 0.002
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 42 0.002
gi|89044853 PREDICTED: similar to telomeric repeat binding facto... 42 0.002
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 41 0.003
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 41 0.003
gi|169212925 PREDICTED: similar to telomeric repeat binding fact... 41 0.004
gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo s... 41 0.004
gi|189409140 telomeric repeat binding factor 1 isoform 2 [Homo s... 41 0.004
gi|5032169 telomeric repeat binding factor 2 [Homo sapiens] 40 0.010
gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens] 38 0.028
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 37 0.081
>gi|4505293 MYB-related protein B [Homo sapiens]
Length = 700
Score = 1422 bits (3681), Expect = 0.0
Identities = 700/700 (100%), Positives = 700/700 (100%)
Query: 1 MSRRTRCEDLDELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASH 60
MSRRTRCEDLDELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASH
Sbjct: 1 MSRRTRCEDLDELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASH 60
Query: 61 FPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQ 120
FPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQ
Sbjct: 61 FPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQ 120
Query: 121 CRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTI 180
CRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTI
Sbjct: 121 CRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTI 180
Query: 181 KRKVDTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEEN 240
KRKVDTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEEN
Sbjct: 181 KRKVDTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEEN 240
Query: 241 SEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLL 300
SEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLL
Sbjct: 241 SEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLL 300
Query: 301 IPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQ 360
IPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQ
Sbjct: 301 IPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQ 360
Query: 361 PSALVPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVAL 420
PSALVPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVAL
Sbjct: 361 PSALVPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVAL 420
Query: 421 SPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCS 480
SPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCS
Sbjct: 421 SPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCS 480
Query: 481 QKVVVTTPLHRDKTPLHQKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPH 540
QKVVVTTPLHRDKTPLHQKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPH
Sbjct: 481 QKVVVTTPLHRDKTPLHQKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPH 540
Query: 541 LEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMS 600
LEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMS
Sbjct: 541 LEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMS 600
Query: 601 TLPKSLSLPTTAPSNSSSLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMS 660
TLPKSLSLPTTAPSNSSSLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMS
Sbjct: 601 TLPKSLSLPTTAPSNSSSLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMS 660
Query: 661 SAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLILS 700
SAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLILS
Sbjct: 661 SAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLILS 700
>gi|122937231 v-myb myeloblastosis viral oncogene homolog
(avian)-like 1 isoform 1 [Homo sapiens]
Length = 752
Score = 466 bits (1200), Expect = e-131
Identities = 303/776 (39%), Positives = 435/776 (56%), Gaps = 101/776 (13%)
Query: 1 MSRRTRCEDLDE-LHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKF 56
M++R+R ED D+ L Y D D +VP+Q+ K +VKWT +ED++L+ LV Q G DW
Sbjct: 1 MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTL 60
Query: 57 LASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGR 116
+ASH NR+D QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W+LIAKHLKGR
Sbjct: 61 IASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGR 120
Query: 117 LGKQCRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHW 176
+GKQCRERWHNHLNPEVKKS WTEEEDRII EAHK LGNRWAEIAK+LPGRTDN++KNHW
Sbjct: 121 IGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHW 180
Query: 177 NSTIKRKVDTGGFLSES------------KDC--------KPPVYLLLEL-------EDK 209
NST++RKV+ G+L + K C + Y+ +++ +
Sbjct: 181 NSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCAAMDHMQTQNQFYIPVQIPGYQYVSPEG 240
Query: 210 DGLQSAQPTEG--QGSLLTNWPSVPPTIKEEE----NSEEELAAATTSKE---------- 253
+ ++ QPT Q + P IKE E ++E E+ +
Sbjct: 241 NCIEHVQPTSAFIQQPFIDEDPDKEKKIKELEMLLMSAENEVRRKRIPSQPGSFSSWSGS 300
Query: 254 ---QEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAVGS--SL 308
+ + L+++ E EF ++ + + + P K++ AN ++ ++ +
Sbjct: 301 FLMDDNMSNTLNSL--DEHTSEFYSMDENQPVSAQQNSPTKFLAVEANAVLSSLQTIPEF 358
Query: 309 SEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQL-QASHQQQVLPPRQPSALVPS 367
+E L+LIESDP AW D++ FD+ + +A I ++ V+L + H + + + +LV
Sbjct: 359 AETLELIESDPVAWSDVTSFDISD--AAASPIKSTPVKLMRIQHNEGAMECQFNVSLV-- 414
Query: 368 VTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENS 427
L+G + E +P+ T + TPP++L+++RK RV SP +E
Sbjct: 415 -----LEGK--KNTCNGGNSEAVPL---TSPNIAKFSTPPAILRKKRKMRVGHSPGSELR 464
Query: 428 TSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTT 487
L+ ++ K TP+KTLPFSPSQF N + L +E+PS TSTP+C QK ++TT
Sbjct: 465 D--GSLNDGGNMALKHTPLKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKALITT 522
Query: 488 PLHRDKTPLHQK-HAAFVTPDQKYS-MDNTPHTPTPFKNAL----EKYGPLKPLPQ-TPH 540
PLH++ TP QK + F TP + S + TP TPTPFKNAL +KYGPLK + Q
Sbjct: 523 PLHKETTPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAF 582
Query: 541 LEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALD----------I 590
LEED++EVL+ E G +L ++++ P + K S KKVRKSL LD +
Sbjct: 583 LEEDIREVLKEETGTDLFLKEEDEPAYKSCKQENTASG-KKVRKSLVLDNWEKEESGTQL 641
Query: 591 VDEDVKLMMS--TLPKSLSLPTTAPSNSSSLTLSGIKEDNSLLNQGFLQAK----PEKAA 644
+ ED+ M S SL + + + L K+D + N+ + K P +
Sbjct: 642 LTEDISDMQSENRFTTSLLMIPLLEIHDNRCNLIPEKQDINSTNKTYTLTKKKPNPNTSK 701
Query: 645 VAQKPRSHFTTPAPMSSAWKTVACGGTRDQLFMQEKARQLLGR-LKPSHTSRTLIL 699
V + ++ + W+TV G T DQL M E+AR+ L S TSR LIL
Sbjct: 702 VVKLEKN-----LQSNCEWETVVYGKTEDQLIMTEQARRYLSTYTATSSTSRALIL 752
>gi|221139773 v-myb myeloblastosis viral oncogene homolog
(avian)-like 1 isoform 2 [Homo sapiens]
Length = 692
Score = 452 bits (1163), Expect = e-127
Identities = 293/760 (38%), Positives = 417/760 (54%), Gaps = 129/760 (16%)
Query: 1 MSRRTRCEDLDE-LHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKF 56
M++R+R ED D+ L Y D D +VP+Q+ K +VKWT +ED++L+ LV Q G DW
Sbjct: 1 MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTL 60
Query: 57 LASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGR 116
+ASH NR+D QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W+LIAKHLKGR
Sbjct: 61 IASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGR 120
Query: 117 LGKQCRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHW 176
+GKQCRERWHNHLNPEVKKS WTEEEDRII EAHK LGNRWAEIAK+LPGRTDN++KNHW
Sbjct: 121 IGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHW 180
Query: 177 NSTIKRKVDTGGFLSES------------KDC--------KPPVYLLLEL-------EDK 209
NST++RKV+ G+L + K C + Y+ +++ +
Sbjct: 181 NSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCAAMDHMQTQNQFYIPVQIPGYQYVSPEG 240
Query: 210 DGLQSAQPTEG--QGSLLTNWPSVPPTIKEEE----NSEEELAAATTSKE---------- 253
+ ++ QPT Q + P IKE E ++E E+ +
Sbjct: 241 NCIEHVQPTSAFIQQPFIDEDPDKEKKIKELEMLLMSAENEVRRKRIPSQPGSFSSWSGS 300
Query: 254 ---QEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAVGS--SL 308
+ + L+++ E EF ++ + + + P K++ AN ++ ++ +
Sbjct: 301 FLMDDNMSNTLNSL--DEHTSEFYSMDENQPVSAQQNSPTKFLAVEANAVLSSLQTIPEF 358
Query: 309 SEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQL-QASHQQQVLPPRQPSALVPS 367
+E L+LIESDP AW D++ FD+ + +A I ++ V+L + H + + + +LV
Sbjct: 359 AETLELIESDPVAWSDVTSFDISD--AAASPIKSTPVKLMRIQHNEGAMECQFNVSLV-- 414
Query: 368 VTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENS 427
L+G + E +P+ T + TPP++L+++RK RV SP +E
Sbjct: 415 -----LEGK--KNTCNGGNSEAVPL---TSPNIAKFSTPPAILRKKRKMRVGHSPGSELR 464
Query: 428 TSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTT 487
L+ ++ K TP+KTLPFSPSQF N + L +E+PS TSTP+C QK ++TT
Sbjct: 465 D--GSLNDGGNMALKHTPLKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKALITT 522
Query: 488 PLHRDKTPLHQK-HAAFVTPDQKYS-MDNTPHTPTPFKNAL----EKYGPLKPLPQ-TPH 540
PLH++ TP QK + F TP + S + TP TPTPFKNAL +KYGPLK + Q
Sbjct: 523 PLHKETTPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAF 582
Query: 541 LEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMS 600
LEED++EVL+ E G +L ++++ P + K S KKVRKSL LD +++
Sbjct: 583 LEEDIREVLKEETGTDLFLKEEDEPAYKSCKQENTASG-KKVRKSLVLDNWEKE------ 635
Query: 601 TLPKSLSLPTTAPSNSSSLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMS 660
+ + L I + S +
Sbjct: 636 -------------ESGTQLLTEDISDMQS------------------------------N 652
Query: 661 SAWKTVACGGTRDQLFMQEKARQLLGR-LKPSHTSRTLIL 699
W+TV G T DQL M E+AR+ L S TSR LIL
Sbjct: 653 CEWETVVYGKTEDQLIMTEQARRYLSTYTATSSTSRALIL 692
>gi|239735492 v-myb myeloblastosis viral oncogene homolog isoform 6
[Homo sapiens]
Length = 745
Score = 405 bits (1041), Expect = e-113
Identities = 282/760 (37%), Positives = 382/760 (50%), Gaps = 96/760 (12%)
Query: 8 EDLDELHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNR 64
ED ++ D D D + K K +WT EEDE+L+ LV Q G DWK +A++ PNR
Sbjct: 14 EDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNR 73
Query: 65 TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRER 124
TD QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W++IAKHLKGR+GKQCRER
Sbjct: 74 TDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRER 133
Query: 125 WHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKV 184
WHNHLNPEVKK+ WTEEEDRII +AHK LGNRWAEIAK+LPGRTDNA+KNHWNST++RKV
Sbjct: 134 WHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKV 193
Query: 185 DTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE 244
+ G+L ES P ++ + AQ T P+V SE
Sbjct: 194 EQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISE-- 251
Query: 245 LAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSP---------------PETSLP 289
A +S P+ ++ V P+P +R + P E L
Sbjct: 252 -AQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELK 310
Query: 290 YKWVVEAANLLIPAVGSSLSEALDLIESDPDA---WC---DLSKFDLPEEPSAEDSINNS 343
+ V+ N G + D D+ C S LP +P + + S
Sbjct: 311 GQQVLPTQNHTCSYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPADPGSLPEESAS 370
Query: 344 LVQLQASHQQQVLPPRQPSALVPSVTEY----------RLDGHTISDLSRSSRGELIPIS 393
+ HQ +L S S E+ G + R G
Sbjct: 371 PARCMIVHQGTILDNDSSSWCDLSSFEFFEEADFSPSQHHTGKALQLQQREGNGTKPAGE 430
Query: 394 PSTEVGGSGIG----TPPSVLKRQ----------RKRRVALSPVTENSTSLSFLDSCNSL 439
PS V + PP VL RK+R SP+ S +S
Sbjct: 431 PSPRVNKRMLSESSLDPPKVLPPARHSTIPLVILRKKRGQASPLATGDCSSFIFADVSSS 490
Query: 440 TPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQK 499
TPK +PVK+LPFSPSQFLN + + +LE PSLTSTP+ K+ VTTP HRD+T QK
Sbjct: 491 TPKRSPVKSLPFSPSQFLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQK 550
Query: 500 -HAAFVTPDQKYS-MDNTPHTPTPFKNALE----KYGPLKPLPQTP-HLEEDLKEVLRSE 552
+ F TP K S ++++P TPTPFK+AL KYGPLK LPQTP HL EDL++V++ E
Sbjct: 551 ENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHLVEDLQDVIKQE 610
Query: 553 AGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMS------TLPKSL 606
+ E I E Q+ P L +KK+++ + D+ S +L L
Sbjct: 611 SD-----ESGIVAEFQENGPPL----LKKIKQEVE-SPTDKSGNFFCSHHWEGDSLNTQL 660
Query: 607 SLPTTAPSNSSSLTLSGI-------KEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPM 659
T+ +++ ++ S + EDN L KA K RS + P
Sbjct: 661 FTQTSPVADAPNILTSSVLMAPASEDEDNVL-----------KAFTVPKNRSLASPLQPC 709
Query: 660 SSAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLIL 699
SS W+ +CG +Q+ +AR+ + + ++RTL++
Sbjct: 710 SSTWEPASCGKMEEQMTSSSQARKYVN----AFSARTLVM 745
>gi|239735488 v-myb myeloblastosis viral oncogene homolog isoform 4
[Homo sapiens]
Length = 758
Score = 403 bits (1035), Expect = e-112
Identities = 285/778 (36%), Positives = 388/778 (49%), Gaps = 119/778 (15%)
Query: 8 EDLDELHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNR 64
ED ++ D D D + K K +WT EEDE+L+ LV Q G DWK +A++ PNR
Sbjct: 14 EDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNR 73
Query: 65 TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRER 124
TD QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W++IAKHLKGR+GKQCRER
Sbjct: 74 TDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRER 133
Query: 125 WHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKV 184
WHNHLNPEVKK+ WTEEEDRII +AHK LGNRWAEIAK+LPGRTDNA+KNHWNST++RKV
Sbjct: 134 WHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKV 193
Query: 185 DTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE 244
+ G+L ES P ++ + AQ T P+V SE
Sbjct: 194 EQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISE-- 251
Query: 245 LAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAV 304
A +S P+ ++ V P+P +R + P + K + E LL+
Sbjct: 252 -AQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKE----KRIKELELLLMSTE 306
Query: 305 GSSLSEALDLIESDPDAWCDLSKFD----------------------LPEEPSAEDSINN 342
+ W + D LP +P + +
Sbjct: 307 NELKGQQTQNHTCSYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPADPGSLPEESA 366
Query: 343 SLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTIS--DLSRSSRGELIPISPSTEVGG 400
S + HQ +L + L + T +D + S DLS E SPS G
Sbjct: 367 SPARCMIVHQGTIL-DNVKNLLEFAETLQFIDSDSSSWCDLSSFEFFEEADFSPSQHHTG 425
Query: 401 --------SGIGTPPS------VLKRQ-------------------------RKRRVALS 421
G GT P+ V KR RK+R S
Sbjct: 426 KALQLQQREGNGTKPAGEPSPRVNKRMLSESSLDPPKVLPPARHSTIPLVILRKKRGQAS 485
Query: 422 PVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQ 481
P+ S +S TPK +PVK+LPFSPSQFLN + + +LE PSLTSTP+
Sbjct: 486 PLATGDCSSFIFADVSSSTPKRSPVKSLPFSPSQFLNTSSNHENSDLEMPSLTSTPLIGH 545
Query: 482 KVVVTTPLHRDKTPLHQK-HAAFVTPDQKYS-MDNTPHTPTPFKNALE----KYGPLKPL 535
K+ VTTP HRD+T QK + F TP K S ++++P TPTPFK+AL KYGPLK L
Sbjct: 546 KLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKML 605
Query: 536 PQTP-HLEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDED 594
PQTP HL EDL++V++ E+ E I E Q+ P L +KK+++ + D+
Sbjct: 606 PQTPSHLVEDLQDVIKQESD-----ESGIVAEFQENGPPL----LKKIKQEVE-SPTDKS 655
Query: 595 VKLMMS------TLPKSLSLPTTAPSNSSSLTLSGI-------KEDNSLLNQGFLQAKPE 641
S +L L T+ +++ ++ S + EDN L
Sbjct: 656 GNFFCSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVL----------- 704
Query: 642 KAAVAQKPRSHFTTPAPMSSAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLIL 699
KA K RS + P SS W+ +CG +Q+ +AR+ + + ++RTL++
Sbjct: 705 KAFTVPKNRSLASPLQPCSSTWEPASCGKMEEQMTSSSQARKYVN----AFSARTLVM 758
>gi|194328729 v-myb myeloblastosis viral oncogene homolog isoform 1
[Homo sapiens]
Length = 761
Score = 402 bits (1034), Expect = e-112
Identities = 288/777 (37%), Positives = 389/777 (50%), Gaps = 114/777 (14%)
Query: 8 EDLDELHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNR 64
ED ++ D D D + K K +WT EEDE+L+ LV Q G DWK +A++ PNR
Sbjct: 14 EDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNR 73
Query: 65 TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRER 124
TD QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W++IAKHLKGR+GKQCRER
Sbjct: 74 TDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRER 133
Query: 125 WHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKV 184
WHNHLNPEVKK+ WTEEEDRII +AHK LGNRWAEIAK+LPGRTDNA+KNHWNST++RKV
Sbjct: 134 WHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKV 193
Query: 185 DTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE 244
+ G+L ES P ++ + AQ T P+V SE
Sbjct: 194 EQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISE-- 251
Query: 245 LAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSP---------------PETSLP 289
A +S P+ ++ V P+P +R + P E L
Sbjct: 252 -AQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELK 310
Query: 290 YKWVVEAANLLIPAVGSSLSEALDLIESDPDA---WC---DLSKFDLPEEPSAEDSINNS 343
+ V+ N G + D D+ C S LP +P + + S
Sbjct: 311 GQQVLPTQNHTCSYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPADPGSLPEESAS 370
Query: 344 LVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTIS--DLSRSSRGELIPISPSTEVGG- 400
+ HQ +L + L + T +D + S DLS E SPS G
Sbjct: 371 PARCMIVHQGTIL-DNVKNLLEFAETLQFIDSDSSSWCDLSSFEFFEEADFSPSQHHTGK 429
Query: 401 -------SGIGT---------------------PPSVLKRQR----------KRRVALSP 422
G GT PP VL R K+R SP
Sbjct: 430 ALQLQQREGNGTKPAGEPSPRVNKRMLSESSLDPPKVLPPARHSTIPLVILRKKRGQASP 489
Query: 423 VTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQK 482
+ S +S TPK +PVK+LPFSPSQFLN + + +LE PSLTSTP+ K
Sbjct: 490 LATGDCSSFIFADVSSSTPKRSPVKSLPFSPSQFLNTSSNHENSDLEMPSLTSTPLIGHK 549
Query: 483 VVVTTPLHRDKTPLHQK-HAAFVTPDQKYS-MDNTPHTPTPFKNALE----KYGPLKPLP 536
+ VTTP HRD+T QK + F TP K S ++++P TPTPFK+AL KYGPLK LP
Sbjct: 550 LTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLP 609
Query: 537 QTP-HLEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDV 595
QTP HL EDL++V++ E+ E I E Q+ P L +KK+++ + D+
Sbjct: 610 QTPSHLVEDLQDVIKQESD-----ESGIVAEFQENGPPL----LKKIKQEVE-SPTDKSG 659
Query: 596 KLMMS------TLPKSLSLPTTAPSNSSSLTLSGI-------KEDNSLLNQGFLQAKPEK 642
S +L L T+ +++ ++ S + EDN L K
Sbjct: 660 NFFCSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVL-----------K 708
Query: 643 AAVAQKPRSHFTTPAPMSSAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLIL 699
A K RS + P SS W+ +CG +Q+ +AR+ + + ++RTL++
Sbjct: 709 AFTVPKNRSLASPLQPCSSTWEPASCGKMEEQMTSSSQARKYVN----AFSARTLVM 761
>gi|46361980 v-myb myeloblastosis viral oncogene homolog isoform 2
[Homo sapiens]
Length = 640
Score = 371 bits (952), Expect = e-102
Identities = 261/716 (36%), Positives = 363/716 (50%), Gaps = 113/716 (15%)
Query: 8 EDLDELHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNR 64
ED ++ D D D + K K +WT EEDE+L+ LV Q G DWK +A++ PNR
Sbjct: 14 EDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNR 73
Query: 65 TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRER 124
TD QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W++IAKHLKGR+GKQCRER
Sbjct: 74 TDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRER 133
Query: 125 WHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKV 184
WHNHLNPEVKK+ WTEEEDRII +AHK LGNRWAEIAK+LPGRTDNA+KNHWNST++RKV
Sbjct: 134 WHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKV 193
Query: 185 DTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE 244
+ G+L ES P ++ + AQ T P+V SE
Sbjct: 194 EQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISE-- 251
Query: 245 LAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAV 304
A +S P+ ++ V P+P +R + P + K + E LL+
Sbjct: 252 -AQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKE----KRIKELELLLM--- 303
Query: 305 GSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSAL 364
S E+ + QQVLP + +
Sbjct: 304 ------------------------------STENELKG----------QQVLPTQNHTCS 323
Query: 365 VPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGS-GIGTPPSVLKRQRKRRVALSPV 423
P + HT G+ P+S E + + P L + V
Sbjct: 324 YPGWHSTTIADHT------RPHGDSAPVSCLGEHHSTPSLPADPGSLPEESASPARCMIV 377
Query: 424 TENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKV 483
+ + LD+ +L + +TL F S FLN + + +LE PSLTSTP+ K+
Sbjct: 378 HQG----TILDNVKNLLEFA---ETLQFIDS-FLNTSSNHENSDLEMPSLTSTPLIGHKL 429
Query: 484 VVTTPLHRDKTPLHQK-HAAFVTPDQKYS-MDNTPHTPTPFKNALE----KYGPLKPLPQ 537
VTTP HRD+T QK + F TP K S ++++P TPTPFK+AL KYGPLK LPQ
Sbjct: 430 TVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQ 489
Query: 538 TP-HLEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVK 596
TP HL EDL++V++ E+ E I E Q+ P L +KK+++ + D+
Sbjct: 490 TPSHLVEDLQDVIKQESD-----ESGIVAEFQENGPPL----LKKIKQEVE-SPTDKSGN 539
Query: 597 LMMS------TLPKSLSLPTTAPSNSSSLTLSGI-------KEDNSLLNQGFLQAKPEKA 643
S +L L T+ +++ ++ S + EDN L KA
Sbjct: 540 FFCSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVL-----------KA 588
Query: 644 AVAQKPRSHFTTPAPMSSAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLIL 699
K RS + P SS W+ +CG +Q+ +AR+ + + ++RTL++
Sbjct: 589 FTVPKNRSLASPLQPCSSTWEPASCGKMEEQMTSSSQARKYVN----AFSARTLVM 640
>gi|239735494 v-myb myeloblastosis viral oncogene homolog isoform 7
[Homo sapiens]
Length = 603
Score = 368 bits (945), Expect = e-102
Identities = 259/703 (36%), Positives = 356/703 (50%), Gaps = 124/703 (17%)
Query: 8 EDLDELHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNR 64
ED ++ D D D + K K +WT EEDE+L+ LV Q G DWK +A++ PNR
Sbjct: 14 EDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNR 73
Query: 65 TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRER 124
TD QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W++IAKHLKGR+GKQCRER
Sbjct: 74 TDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRER 133
Query: 125 WHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKV 184
WHNHLNPEVKK+ WTEEEDRII +AHK LGNRWAEIAK+LPGRTDNA+KNHWNST++RKV
Sbjct: 134 WHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKV 193
Query: 185 DTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE 244
+ G+L ES P ++ + AQ T P+V SE
Sbjct: 194 EQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISE-- 251
Query: 245 LAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAV 304
A +S P+ ++ V P+P +R + P + K + E LL+
Sbjct: 252 -AQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKE----KRIKELELLLM--- 303
Query: 305 GSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSAL 364
S E+ + QQVLP + +
Sbjct: 304 ------------------------------STENELKG----------QQVLPTQNHTCS 323
Query: 365 VPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGS-GIGTPPSVLKRQRKRRVALSPV 423
P + HT G+ P+S E + + P L + V
Sbjct: 324 YPGWHSTTIADHT------RPHGDSAPVSCLGEHHSTPSLPADPGSLPEESASPARCMIV 377
Query: 424 TENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKV 483
+ + LD+ +L + +TL F S FLN + + +LE PSLTSTP+ K+
Sbjct: 378 HQG----TILDNVKNLLEFA---ETLQFIDS-FLNTSSNHENSDLEMPSLTSTPLIGHKL 429
Query: 484 VVTTPLHRDKTPLHQK-HAAFVTPDQKYS-MDNTPHTPTPFKNALE----KYGPLKPLPQ 537
VTTP HRD+T QK + F TP K S ++++P TPTPFK+AL KYGPLK LPQ
Sbjct: 430 TVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQ 489
Query: 538 TP-HLEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVK 596
TP HL EDL++V++ E+ E I E Q+ P L +KK+++ +I+ V
Sbjct: 490 TPSHLVEDLQDVIKQESD-----ESGIVAEFQENGPPL----LKKIKQE---NILTSSVL 537
Query: 597 LMMSTLPKSLSLPTTAPSNSSSLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTP 656
+ AP++ EDN L KA K RS +
Sbjct: 538 M--------------APASED--------EDNVL-----------KAFTVPKNRSLASPL 564
Query: 657 APMSSAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLIL 699
P SS W+ +CG +Q+ +AR+ + + ++RTL++
Sbjct: 565 QPCSSTWEPASCGKMEEQMTSSSQARKYVN----AFSARTLVM 603
>gi|239735496 v-myb myeloblastosis viral oncogene homolog isoform 8
[Homo sapiens]
Length = 605
Score = 284 bits (726), Expect = 2e-76
Identities = 183/478 (38%), Positives = 251/478 (52%), Gaps = 35/478 (7%)
Query: 8 EDLDELHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNR 64
ED ++ D D D + K K +WT EEDE+L+ LV Q G DWK +A++ PNR
Sbjct: 14 EDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNR 73
Query: 65 TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRER 124
TD QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W++IAKHLKGR+GKQCRER
Sbjct: 74 TDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRER 133
Query: 125 WHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKV 184
WHNHLNPEVKK+ WTEEEDRII +AHK LGNRWAEIAK+LPGRTDNA+KNHWNST++RKV
Sbjct: 134 WHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKV 193
Query: 185 DTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE 244
+ G+L ES P ++ + AQ T P+V SE
Sbjct: 194 EQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISE-- 251
Query: 245 LAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAV 304
A +S P+ ++ V P+P + ++ S P A+ P
Sbjct: 252 -AQNVSSHVPYPVALHVNIVNVPQPAAAAIQTQNH-----TCSYPGWHSTTIADHTRPHG 305
Query: 305 GSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSAL 364
S+ L S P LP +P + + S + HQ +L + L
Sbjct: 306 DSAPVSCLGEHHSTP---------SLPADPGSLPEESASPARCMIVHQGTIL-DNVKNLL 355
Query: 365 VPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGS--GIGTP---PSVLKRQRKRRVA 419
+ T +D + + + +P ST + G + TP +K Q++ V
Sbjct: 356 EFAETLQFIDSFLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQKENTVF 415
Query: 420 LSPVTENS-------TSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELES 470
+P + S T F + + K P+K LP +PS + + QD ++ ES
Sbjct: 416 RTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHLVE--DLQDVIKQES 471
Score = 175 bits (443), Expect = 1e-43
Identities = 182/654 (27%), Positives = 283/654 (43%), Gaps = 121/654 (18%)
Query: 81 LVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWTE 140
L K WT+EED+K+ +LV++ GT W +IA +L R QC+ RW LNPE+ K WT+
Sbjct: 38 LGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTK 97
Query: 141 EEDRIICEAHKVLG-NRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFLSESKDCKPP 199
EED+ + E + G RW+ IAK L GR + W++ + +V + E
Sbjct: 98 EEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDR---- 153
Query: 200 VYLLLELEDKDGLQSAQ-----PTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQ 254
++ + + G + A+ P ++ +W S E+E +E +SK
Sbjct: 154 --IIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQE-----SSKAS 206
Query: 255 EPIGTDLDAVRTPEPLEEFPKREDQEG---SPPETSLPYKWVVEAANLLIPAVGSS---- 307
+P AV T F K G +PP LP P V +
Sbjct: 207 QP------AVAT-----SFQKNSHLMGFAQAPPTAQLPATGQ--------PTVNNDYSYY 247
Query: 308 -LSEALDLIESDP-DAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALV 365
+SEA ++ P ++ ++P+ +A N H + +P
Sbjct: 248 HISEAQNVSSHVPYPVALHVNIVNVPQPAAAAIQTQNHTCSYPGWHSTTIADHTRPHG-- 305
Query: 366 PSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTE 425
D +S L +P P G+ P + A +
Sbjct: 306 --------DSAPVSCLGEHHSTPSLPADP---------GSLP-----EESASPARCMIVH 343
Query: 426 NSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVV 485
T LD+ +L + +TL F S FLN + + +LE PSLTSTP+ K+ V
Sbjct: 344 QGT---ILDNVKNLLEFA---ETLQFIDS-FLNTSSNHENSDLEMPSLTSTPLIGHKLTV 396
Query: 486 TTPLHRDKTPLHQK-HAAFVTPDQKYS-MDNTPHTPTPFKNALE----KYGPLKPLPQTP 539
TTP HRD+T QK + F TP K S ++++P TPTPFK+AL KYGPLK LPQTP
Sbjct: 397 TTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTP 456
Query: 540 -HLEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLM 598
HL EDL++V++ E+ E I E Q+ P L +KK+++ + D+
Sbjct: 457 SHLVEDLQDVIKQESD-----ESGIVAEFQENGPPL----LKKIKQEVE-SPTDKSGNFF 506
Query: 599 MS------TLPKSLSLPTTAPSNSSSLTLSGI-------KEDNSLLNQGFLQAKPEKAAV 645
S +L L T+ +++ ++ S + EDN L KA
Sbjct: 507 CSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVL-----------KAFT 555
Query: 646 AQKPRSHFTTPAPMSSAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLIL 699
K RS + P SS W+ +CG +Q+ +AR+ + + ++RTL++
Sbjct: 556 VPKNRSLASPLQPCSSTWEPASCGKMEEQMTSSSQARKYVN----AFSARTLVM 605
>gi|239735490 v-myb myeloblastosis viral oncogene homolog isoform 5
[Homo sapiens]
Length = 555
Score = 283 bits (724), Expect = 4e-76
Identities = 143/279 (51%), Positives = 181/279 (64%), Gaps = 6/279 (2%)
Query: 8 EDLDELHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNR 64
ED ++ D D D + K K +WT EEDE+L+ LV Q G DWK +A++ PNR
Sbjct: 14 EDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNR 73
Query: 65 TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRER 124
TD QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W++IAKHLKGR+GKQCRER
Sbjct: 74 TDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRER 133
Query: 125 WHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKV 184
WHNHLNPEVKK+ WTEEEDRII +AHK LGNRWAEIAK+LPGRTDNA+KNHWNST++RKV
Sbjct: 134 WHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKV 193
Query: 185 DTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE 244
+ G+L ES P ++ + AQ T P+V SE
Sbjct: 194 EQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISE-- 251
Query: 245 LAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSP 283
A +S P+ ++ V P+P +R + P
Sbjct: 252 -AQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDP 289
Score = 113 bits (282), Expect = 7e-25
Identities = 90/264 (34%), Positives = 135/264 (51%), Gaps = 45/264 (17%)
Query: 456 FLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQK-HAAFVTPDQKYS-MD 513
FLN + + +LE PSLTSTP+ K+ VTTP HRD+T QK + F TP K S ++
Sbjct: 317 FLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILE 376
Query: 514 NTPHTPTPFKNALE----KYGPLKPLPQTP-HLEEDLKEVLRSEAGIELIIEDDIRPEKQ 568
++P TPTPFK+AL KYGPLK LPQTP HL EDL++V++ E+ E I E Q
Sbjct: 377 SSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHLVEDLQDVIKQESD-----ESGIVAEFQ 431
Query: 569 KRKPGLRRSPIKKVRKSLALDIVDEDVKLMMS------TLPKSLSLPTTAPSNSSSLTLS 622
+ P L +KK+++ + D+ S +L L T+ +++ ++ S
Sbjct: 432 ENGPPL----LKKIKQEVE-SPTDKSGNFFCSHHWEGDSLNTQLFTQTSPVADAPNILTS 486
Query: 623 GI-------KEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMSSAWKTVACGGTRDQL 675
+ EDN L KA K RS + P SS W+ +CG +Q+
Sbjct: 487 SVLMAPASEDEDNVL-----------KAFTVPKNRSLASPLQPCSSTWEPASCGKMEEQM 535
Query: 676 FMQEKARQLLGRLKPSHTSRTLIL 699
+AR+ + + ++RTL++
Sbjct: 536 TSSSQARKYVN----AFSARTLVM 555
>gi|194328727 v-myb myeloblastosis viral oncogene homolog isoform 3
[Homo sapiens]
Length = 637
Score = 283 bits (724), Expect = 4e-76
Identities = 143/279 (51%), Positives = 181/279 (64%), Gaps = 6/279 (2%)
Query: 8 EDLDELHYQDTDSDVPEQRDSKC---KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNR 64
ED ++ D D D + K K +WT EEDE+L+ LV Q G DWK +A++ PNR
Sbjct: 14 EDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNR 73
Query: 65 TDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRER 124
TD QCQ+RW +VLNP+L+KGPWTKEEDQ+VIELV+KYG K+W++IAKHLKGR+GKQCRER
Sbjct: 74 TDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRER 133
Query: 125 WHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKV 184
WHNHLNPEVKK+ WTEEEDRII +AHK LGNRWAEIAK+LPGRTDNA+KNHWNST++RKV
Sbjct: 134 WHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKV 193
Query: 185 DTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE 244
+ G+L ES P ++ + AQ T P+V SE
Sbjct: 194 EQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISE-- 251
Query: 245 LAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSP 283
A +S P+ ++ V P+P +R + P
Sbjct: 252 -AQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDP 289
Score = 180 bits (457), Expect = 3e-45
Identities = 187/661 (28%), Positives = 297/661 (44%), Gaps = 103/661 (15%)
Query: 81 LVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWTE 140
L K WT+EED+K+ +LV++ GT W +IA +L R QC+ RW LNPE+ K WT+
Sbjct: 38 LGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTK 97
Query: 141 EEDRIICEAHKVLG-NRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFLSESKDCKPP 199
EED+ + E + G RW+ IAK L GR + W++ + +V + E
Sbjct: 98 EEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDR---- 153
Query: 200 VYLLLELEDKDGLQSAQ-----PTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQ 254
++ + + G + A+ P ++ +W S E+E +E +SK
Sbjct: 154 --IIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQE-----SSKAS 206
Query: 255 EPIGTDLDAVRTPEPLEEFPKREDQEG---SPPETSLP------------YKWVVEAANL 299
+P AV T F K G +PP LP Y + EA N+
Sbjct: 207 QP------AVAT-----SFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISEAQNV 255
Query: 300 LIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPR 359
V ++ ++++ A + + E+P E I + L ++ + L +
Sbjct: 256 S-SHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENE--LKGQ 312
Query: 360 QPSALVPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGS-GIGTPPSVLKRQRKRRV 418
Q S + TI+D +R G+ P+S E + + P L +
Sbjct: 313 QTQNHTCSYPGWH--STTIADHTRP-HGDSAPVSCLGEHHSTPSLPADPGSLPEESASPA 369
Query: 419 ALSPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPV 478
V + + LD+ +L + +TL F S FLN + + +LE PSLTSTP+
Sbjct: 370 RCMIVHQGT----ILDNVKNLLEFA---ETLQFIDS-FLNTSSNHENSDLEMPSLTSTPL 421
Query: 479 CSQKVVVTTPLHRDKTPLHQK-HAAFVTPDQKYS-MDNTPHTPTPFKNALE----KYGPL 532
K+ VTTP HRD+T QK + F TP K S ++++P TPTPFK+AL KYGPL
Sbjct: 422 IGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPL 481
Query: 533 KPLPQTP-HLEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIV 591
K LPQTP HL EDL++V++ E+ E I E Q+ P L +KK+++ +
Sbjct: 482 KMLPQTPSHLVEDLQDVIKQESD-----ESGIVAEFQENGPPL----LKKIKQEVE-SPT 531
Query: 592 DEDVKLMMS------TLPKSLSLPTTAPSNSSSLTLSGI-------KEDNSLLNQGFLQA 638
D+ S +L L T+ +++ ++ S + EDN L
Sbjct: 532 DKSGNFFCSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVL-------- 583
Query: 639 KPEKAAVAQKPRSHFTTPAPMSSAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLI 698
KA K RS + P SS W+ +CG +Q+ +AR+ + + ++RTL+
Sbjct: 584 ---KAFTVPKNRSLASPLQPCSSTWEPASCGKMEEQMTSSSQARKYVN----AFSARTLV 636
Query: 699 L 699
+
Sbjct: 637 M 637
>gi|92859678 small nuclear RNA activating complex, polypeptide 4,
190kDa [Homo sapiens]
Length = 1469
Score = 97.1 bits (240), Expect = 5e-20
Identities = 52/155 (33%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 33 KWTHEEDEQLRALVRQF---GQQDWKFLASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKE 89
+WT EED L LV++ ++ + + R Q YRW + L+P L KG W E
Sbjct: 348 EWTEEEDRMLTQLVQEMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPE 407
Query: 90 EDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWT-EEEDRIICE 148
ED K+++ V KYG + W I + + GR QCR+R+ L+ +KK W +EE+++I
Sbjct: 408 EDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIEL 467
Query: 149 AHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRK 183
K WA+IA LP R+ + + W + +K
Sbjct: 468 IEKYGVGHWAKIASELPHRSGSQCLSKWKIMMGKK 502
Score = 53.5 bits (127), Expect = 6e-07
Identities = 29/107 (27%), Positives = 60/107 (56%), Gaps = 4/107 (3%)
Query: 45 LVRQFGQQDWKFLAS-HFP-NRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYG 102
L + DW+ +++ +F +R+ ++ + W +P + K W++EE++++ + +G
Sbjct: 254 LGNRLDSHDWEKISNINFEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHG 313
Query: 103 TKQWTLIAKHL-KGRLGKQCRERWHNHLNPEVKKSCWTEEEDRIICE 148
+W IA+ L R QC +++ H N +K+ WTEEEDR++ +
Sbjct: 314 HLEWQKIAEELGTSRSAFQCLQKFQQH-NKALKRKEWTEEEDRMLTQ 359
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 13/66 (19%)
Query: 21 DVPEQRDSKC-------------KVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNRTDQ 67
+VP + D++C K +W +E+EQL L+ ++G W +AS P+R+
Sbjct: 430 EVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVGHWAKIASELPHRSGS 489
Query: 68 QCQYRW 73
QC +W
Sbjct: 490 QCLSKW 495
>gi|11067747 CDC5-like [Homo sapiens]
Length = 802
Score = 71.6 bits (174), Expect = 2e-12
Identities = 107/468 (22%), Positives = 187/468 (39%), Gaps = 90/468 (19%)
Query: 84 GPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWTEEED 143
G W ED+ + V KYG QW+ IA L + KQC+ RW+ L+P +KK+ W+ EE+
Sbjct: 9 GVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEE 68
Query: 144 RIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTG--------------GF 189
+ K++ +W IA ++ GRT H+ + + G
Sbjct: 69 EKLLHLAKLMPTQWRTIAPII-GRTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGE 127
Query: 190 LSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEE---LA 246
+ + + KP +++ D+D L+ + L N K E EE LA
Sbjct: 128 IDPNPETKPARPDPIDM-DEDELEMLSEARAR---LANTQGKKAKRKAREKQLEEARRLA 183
Query: 247 AATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLLIPAVG- 305
A +E G ++ KR+ + G +P++ PA+G
Sbjct: 184 ALQKRRELRAAGIEIQ-----------KKRKRKRGVDYNAEIPFE--------KKPALGF 224
Query: 306 -SSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSAL 364
+ E +++D + L + DL E +E + Q H ++ PSA+
Sbjct: 225 YDTSEENYQALDAD---FRKLRQQDLDGELRSEKEGRDRKKDKQ--HLKRKKESDLPSAI 279
Query: 365 VPS--VTEYRLDGHTI----SDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRV 418
+ + V+E+ + +S + E++ + ++E+ R+
Sbjct: 280 LQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIA----------------RQT 323
Query: 419 ALSPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPV 478
A NS S + L N +T S ++T P +P+ QD + E+ +L +
Sbjct: 324 AEESGITNSASSTLLSEYN-VTNNSVALRT-PRTPA-------SQDRILQEAQNLMAL-- 372
Query: 479 CSQKVVVTTPLHRD-KTPLHQKHAAFVTPDQKYSMDNTPHT--PTPFK 523
V TPL TPLH+ + VTP ++ + TP+T TPF+
Sbjct: 373 ----TNVDTPLKGGLNTPLHESDFSGVTPQRQ--VVQTPNTVLSTPFR 414
Score = 70.5 bits (171), Expect = 5e-12
Identities = 38/109 (34%), Positives = 61/109 (55%), Gaps = 4/109 (3%)
Query: 34 WTHEEDEQLRALVRQFGQQDWKFLASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQK 93
W + EDE L+A V ++G+ W +AS ++ +QC+ RW L+P + K W++EE++K
Sbjct: 11 WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEK 70
Query: 94 VIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWTEEE 142
++ L K T QW IA + GR QC E + L+ ++ EEE
Sbjct: 71 LLHLAKLMPT-QWRTIAP-IIGRTAAQCLEHYEFLLDKAAQRD--NEEE 115
>gi|215599992 cyclin D binding myb-like transcription factor 1
isoform a [Homo sapiens]
Length = 760
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/122 (27%), Positives = 63/122 (51%), Gaps = 14/122 (11%)
Query: 33 KWTHEEDEQLRALVRQFGQQDWKFLASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQ 92
K+T EE E+L+ L + G DW + + R+ + R R++ G WT+EE++
Sbjct: 226 KYTPEEIEKLKELRIKHGN-DWATIGAAL-GRSASSVKDR-CRLMKDTCNTGKWTEEEEK 282
Query: 93 KVIELVKKYGTKQ----------WTLIAKHLKGRLGKQCRERWHNHLN-PEVKKSCWTEE 141
++ E+V + + + W +A+ + R KQCR +W N+LN + + WT+E
Sbjct: 283 RLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKE 342
Query: 142 ED 143
++
Sbjct: 343 DE 344
>gi|215599981 cyclin D binding myb-like transcription factor 1
isoform b [Homo sapiens]
Length = 672
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/122 (27%), Positives = 63/122 (51%), Gaps = 14/122 (11%)
Query: 33 KWTHEEDEQLRALVRQFGQQDWKFLASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQ 92
K+T EE E+L+ L + G DW + + R+ + R R++ G WT+EE++
Sbjct: 138 KYTPEEIEKLKELRIKHGN-DWATIGAAL-GRSASSVKDR-CRLMKDTCNTGKWTEEEEK 194
Query: 93 KVIELVKKYGTKQ----------WTLIAKHLKGRLGKQCRERWHNHLN-PEVKKSCWTEE 141
++ E+V + + + W +A+ + R KQCR +W N+LN + + WT+E
Sbjct: 195 RLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKE 254
Query: 142 ED 143
++
Sbjct: 255 DE 256
>gi|215599967 cyclin D binding myb-like transcription factor 1
isoform a [Homo sapiens]
Length = 760
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/122 (27%), Positives = 63/122 (51%), Gaps = 14/122 (11%)
Query: 33 KWTHEEDEQLRALVRQFGQQDWKFLASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQ 92
K+T EE E+L+ L + G DW + + R+ + R R++ G WT+EE++
Sbjct: 226 KYTPEEIEKLKELRIKHGN-DWATIGAAL-GRSASSVKDR-CRLMKDTCNTGKWTEEEEK 282
Query: 93 KVIELVKKYGTKQ----------WTLIAKHLKGRLGKQCRERWHNHLN-PEVKKSCWTEE 141
++ E+V + + + W +A+ + R KQCR +W N+LN + + WT+E
Sbjct: 283 RLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKE 342
Query: 142 ED 143
++
Sbjct: 343 DE 344
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 43.1 bits (100), Expect = 9e-04
Identities = 98/456 (21%), Positives = 155/456 (33%), Gaps = 43/456 (9%)
Query: 210 DGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEP 269
+G T G+GS T S+P + +SE +AT P+ T +A +P
Sbjct: 910 EGTSMPTSTPGEGS--TPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTT 967
Query: 270 LE--EFPKREDQEGSPPETSLPYKWVV----EAANLLIPAVGSS--LSEALDLIESDPDA 321
E P EG+ P TS P + EA+ L V S+ L+ + + P A
Sbjct: 968 AEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTA 1027
Query: 322 WCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDL 381
P E S + + AS + L P VT Y S
Sbjct: 1028 EGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTP-VTTY----SQASSS 1082
Query: 382 SRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCN-SLT 440
S ++ G +P S +E G + + + P + + T TS+ S S +
Sbjct: 1083 STTADGTSMPTSTYSE-GSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSS 1141
Query: 441 PKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKH 500
P + ++P SP E +P L S PV + VV + TP+ K
Sbjct: 1142 PTTAEGTSIPTSPPS-----------EGTTP-LASMPVSTTLVVSSEANTLSTTPVDSKT 1189
Query: 501 AAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLP--QTPHLEEDLKEVLRSEAGIELI 558
+ + T P E+ PL +P TP + + S
Sbjct: 1190 QVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTP 1249
Query: 559 IEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSSS 618
+ SP SL E L+ S +P S +L T+P S+
Sbjct: 1250 VTTSAETSS---------SPTTAEGTSLPTSTTSEGSTLLTS-IPVSTTL-VTSPEASTL 1298
Query: 619 LTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFT 654
LT + + ++ + + P A P S ++
Sbjct: 1299 LT-TPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYS 1333
Score = 42.7 bits (99), Expect = 0.001
Identities = 87/431 (20%), Positives = 161/431 (37%), Gaps = 41/431 (9%)
Query: 211 GLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPL 270
G+ + P+EG L S+P + E + T P+ T + +P P
Sbjct: 3035 GIPISTPSEGSTPLT----SIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPA 3090
Query: 271 E--EFPKREDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKF 328
E P EGS P T +P + I + ++ + + + +A +
Sbjct: 3091 EGTSMPISTYSEGSTPLTGVPVS-TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTS 3149
Query: 329 DLPEEPSAEDSINNS-LVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRG 387
+ P++ S ++ L + S V + P T + T + S ++ G
Sbjct: 3150 EGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG 3209
Query: 388 ELIPISPSTEVGGSGIGTPP---SVLKRQRKRRVALSPVTENSTSLSFLDSCNS------ 438
IP S +E G + + + P + + ++ +PV N+ + ++ +S
Sbjct: 3210 TSIPTSTPSE-GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEG 3268
Query: 439 -----LTPK--STPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHR 491
TP STP+ ++P S + + ++ TL +P+ TSTPV + ++P
Sbjct: 3269 TSMPTSTPSEGSTPLTSMPVSTTTVAS--SETSTLST-TPADTSTPVTTYSQASSSPPIA 3325
Query: 492 DKTPLHQKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRS 551
D T + P YS +TP T F L TP ++ +
Sbjct: 3326 DGTSM---------PTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP-VDTSTPVTTST 3375
Query: 552 EAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTT 611
EA + + G +P+ + S +V +V + +T S +L TT
Sbjct: 3376 EASLSPTTAEGTSIPTSSPSEGT--TPLASMPVSTT-PVVSSEVNTLSTTPVDSNTLVTT 3432
Query: 612 APSNSSSLTLS 622
+ SSS T++
Sbjct: 3433 STEASSSPTIA 3443
Score = 42.0 bits (97), Expect = 0.002
Identities = 74/342 (21%), Positives = 120/342 (35%), Gaps = 36/342 (10%)
Query: 217 PTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLE--EFP 274
P+EG LLT S+P +I + E + T P+ T + +P P E P
Sbjct: 801 PSEGS-PLLT---SIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMP 856
Query: 275 KREDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEP 334
EG P TS+P + A + + + + + + S +
Sbjct: 857 TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT 916
Query: 335 SAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLS-RSSRGELIPIS 393
S + L + S V + + P T + T + S ++ G IP S
Sbjct: 917 STPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTS 976
Query: 394 PSTEVGGSGIGTPPS--VLKRQRKRRVALSPVTENSTSLSFLDSCNSLTPK--------- 442
+E TP S ++ ++ +PV N T L+ +S P
Sbjct: 977 TPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSN-TPLTTSTEASSPPPTAEGTSMPTS 1035
Query: 443 -----STPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLH 497
STP+ +P S + + ++ TL +P+ TSTPV + ++ D T +
Sbjct: 1036 TPSEGSTPLTRMPVSTTMVAS--SETSTLS-TTPADTSTPVTTYSQASSSSTTADGTSM- 1091
Query: 498 QKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTP 539
P YS +TP T P L L TP
Sbjct: 1092 --------PTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTP 1125
Score = 40.0 bits (92), Expect = 0.007
Identities = 91/448 (20%), Positives = 154/448 (34%), Gaps = 46/448 (10%)
Query: 210 DGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEP 269
+G A T +GS T S+P + +SE + T + P+ T +P
Sbjct: 1853 EGTSIATSTPSEGS--TALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTT 1910
Query: 270 LE--EFPKREDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSK 327
+ P +EG PP TS+P A+ I + ++L++ + + A +
Sbjct: 1911 ADGSSMPTSTPREGRPPLTSIPVS-TTTVASSEINTLSTTLADTRTPVTTYSQASSSPTT 1969
Query: 328 FD---LPEEPSAEDSINNSLVQLQ----ASHQQQVLPPRQPSALVPSVTEYR-------L 373
D +P +E S + + L S + L P+ T
Sbjct: 1970 ADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTA 2029
Query: 374 DGHTISDLSRSSRGELI---PISPSTEVGGSG--IGTPPSVLKRQ--RKRRVALSPVTEN 426
G +I + S R + P+S + V G + T P K Q + S E
Sbjct: 2030 GGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEG 2089
Query: 427 STSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVT 486
S+ S S S P+ T P + E+ +L++TPV S V+T
Sbjct: 2090 SSMTISAPSEGSPLLTSIPLSTTPVASP--------------EASTLSTTPVDSNSPVIT 2135
Query: 487 TPLHRDKTPLHQKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLK 546
+ +P+ + + T YS TP T P + + L TP ++
Sbjct: 2136 S-TEVSSSPIPTEGTSMQT--STYSDRRTPLTSMPVSTTVVASSAISTLSTTP-VDTSTP 2191
Query: 547 EVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSL 606
+EA + P +P + S + E L + + S
Sbjct: 2192 VTNSTEARSSPTTSEG--TSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST 2249
Query: 607 SLPTTAPSNSSSLTLSGIKEDNSLLNQG 634
+ T+ + SS T G S L++G
Sbjct: 2250 PVTTSTEATSSPTTAEGTSIPTSTLSEG 2277
Score = 38.9 bits (89), Expect = 0.016
Identities = 94/458 (20%), Positives = 147/458 (32%), Gaps = 69/458 (15%)
Query: 210 DGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEP 269
+G T +GS L S+P + + E T + P+ T + +P P
Sbjct: 1264 EGTSLPTSTTSEGSTLLT--SIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTP 1321
Query: 270 LE--EFPKREDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSK 327
E P EG P TS+P + A S A+ ++ +
Sbjct: 1322 AEGTSMPTSTYSEGRTPLTSIPVNTTLVA------------SSAISILST---------- 1359
Query: 328 FDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRG 387
P + S + + + + +P PS +T + + S +S
Sbjct: 1360 --TPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVS-SEASTL 1416
Query: 388 ELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCNSLTP-KSTPV 446
P+ ST S T SP T S+ TP KS PV
Sbjct: 1417 SATPVDTSTPGTTSAEATS--------------SPTTAEGISIPTSTPSEGKTPLKSIPV 1462
Query: 447 KTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVT-TPLHRDKTPLHQKHAAFVT 505
P + S E+ +L++TPV S VVT T + TP A T
Sbjct: 1463 SNTPVANS--------------EASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAIST 1508
Query: 506 PDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIELIIEDDIRP 565
P S +T T P + L TP + S+A D
Sbjct: 1509 P----SEGSTALTSIPVSTTTVASSEINSLSTTPAV-TSTPVTTYSQASSSPTTADGTSM 1563
Query: 566 EKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSSSLTLSGIK 625
+ G +P+ + S L +V + + +T S + T + SSS T G
Sbjct: 1564 QTSTYSEG--STPLTSLPVSTML-VVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSS 1620
Query: 626 EDNSLLNQG--FLQAKPEKAAVAQKPRSHFTTPAPMSS 661
S ++G L + P P + + P+ S
Sbjct: 1621 MTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDS 1658
Score = 37.7 bits (86), Expect = 0.036
Identities = 70/309 (22%), Positives = 117/309 (37%), Gaps = 35/309 (11%)
Query: 212 LQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLE 271
+ ++ P+EG T + S+P + SE +AT P+ T +A +P E
Sbjct: 2210 MPTSTPSEGS----TPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAE 2265
Query: 272 --EFPKREDQEGSPPETSLPYKWVV----EAANLLIPAVGSSLSEALDLIESDPDAWCDL 325
P EG+ P TS+P + E + L V S+ S P +
Sbjct: 2266 GTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEG 2325
Query: 326 SKFDLPEEPSAEDSINNSLVQLQ------ASHQQQVLPPRQPSALVPSVTEYRLDGHTIS 379
+ +P S+E N L ++ AS + L P VT Y G + +
Sbjct: 2326 T--SMPTSTSSEG--NTPLTRMPVSTTMVASFETSTLSTTPADTSTP-VTTYSQAGSSPT 2380
Query: 380 DLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCNSL 439
+S ST + + T P V + +PV + ST ++ +S
Sbjct: 2381 TADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTH--STTPV-DTSTPVTTSTEASS- 2436
Query: 440 TPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQK--VVVTTPLHRDKTPLH 497
+P + ++P SP + T L S +++TPV S + + TTP+ TP+
Sbjct: 2437 SPTTAEGTSIPTSPP-------SEGTTPLASMPVSTTPVVSSEAGTLSTTPVD-TSTPMT 2488
Query: 498 QKHAAFVTP 506
A +P
Sbjct: 2489 TSTEASSSP 2497
Score = 37.7 bits (86), Expect = 0.036
Identities = 94/450 (20%), Positives = 149/450 (33%), Gaps = 53/450 (11%)
Query: 230 SVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGS----PPE 285
S+P T E +S A T+ P T T P+ P + G+ P +
Sbjct: 2779 SIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPL--TSMPVNHTPVASSEAGTLSTTPVD 2836
Query: 286 TSLPYKWVVEAANLLIPAVG-----SSLSEALDLIESDPDAWCDLSKFDL------PEEP 334
TS P +A++ A G S+ SE L+ S P + ++ + P +
Sbjct: 2837 TSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDT 2896
Query: 335 SAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLD-----GHTISDLSRSSRGEL 389
S + + + + +P PS + +T + G S LS +
Sbjct: 2897 SIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTR 2956
Query: 390 IPISPSTEVGGS-----GIGTPPSVLKRQRKRRVALS----PVTENSTSLSFLDSCNSLT 440
P++ S E S G P S +R ++S PV + S ++ T
Sbjct: 2957 TPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTST 3016
Query: 441 PKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKH 500
P +T + SP+ T S LTS PV + V + TP+
Sbjct: 3017 PVTTSTEASS-SPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNS 3075
Query: 501 AAFVT---------------PDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDL 545
+ P YS +TP T P + L TP ++
Sbjct: 3076 PVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTP-VDTST 3134
Query: 546 KEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKS 605
+EA + P +P+ + S L + ED L S P
Sbjct: 3135 PVTTSTEAHSSPTTSEG--TSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTL--SATPVD 3190
Query: 606 LSLP-TTAPSNSSSLTLSGIKEDNSLLNQG 634
S P TT+ +SS T G S ++G
Sbjct: 3191 TSTPVTTSTEATSSTTAEGTSIPTSTPSEG 3220
Score = 35.8 bits (81), Expect = 0.14
Identities = 90/419 (21%), Positives = 144/419 (34%), Gaps = 56/419 (13%)
Query: 217 PTEGQGSLLTNWP-------SVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEP 269
PTEG + + S+P + +S + T P+ +A +P
Sbjct: 2145 PTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTT 2204
Query: 270 LE--EFPKREDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSK 327
E P EGS P TS+P +P V SEA L + D
Sbjct: 2205 SEGTSMPTSTPSEGSTPFTSMPVS--------TMPVV---TSEASTLSATPVDT------ 2247
Query: 328 FDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRG 387
P S E + + + + + + P +P V+ + +S LS +
Sbjct: 2248 -STPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIP-VSHTLVANSEVSTLSTTPVD 2305
Query: 388 ELIPISPSTEVGG---SGIGTP-PSVLKRQRKRRVALSPVTENSTSLSFLDSCNSLTPK- 442
P + STE + GT P+ + + PV+ + SF S S TP
Sbjct: 2306 SNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVA-SFETSTLSTTPAD 2364
Query: 443 -STPVKTLP---FSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQ 498
STPV T SP+ + T S LTS PV + VV + TP+
Sbjct: 2365 TSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDT 2424
Query: 499 KHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIELI 558
+ + S T P E PL +P + V+ SEAG
Sbjct: 2425 STPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVS------TTPVVSSEAG---- 2474
Query: 559 IEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSS 617
P +P+ ++ + ED+ + +ST + +L T+ P +++
Sbjct: 2475 --------TLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTT 2525
Score = 33.5 bits (75), Expect = 0.69
Identities = 78/395 (19%), Positives = 133/395 (33%), Gaps = 43/395 (10%)
Query: 256 PIGTDLDAVRTPEPLEE--FPKREDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALD 313
P+ T A +P E PK + EGS P TS+P + A++ I + + + +
Sbjct: 187 PLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTP 246
Query: 314 LIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRL 373
+ S + + SA + L ++ S V + P+ T +
Sbjct: 247 VTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPV 306
Query: 374 DGHTISDLS-RSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALS----------- 421
T + S ++ G IP S TE TP S + LS
Sbjct: 307 ITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVT 366
Query: 422 --------PVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFW-NKQDTLELESPS 472
P T +TS+ ++L+ STP+ +P S + + T+ ++S +
Sbjct: 367 TSTEPSSLPTTAEATSML----TSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKT 422
Query: 473 LTST-------PVCSQKVVVTTPLHRD-KTPLHQKHAAFVTPDQKYSMDNTPHTPTPFKN 524
+T P ++ + T + TPL + TP N TP K
Sbjct: 423 FVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVS-TTPVASSEASNLSTTPVDSKT 481
Query: 525 ALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIELI-IEDDIRPEKQKRKPGLRRSPIKKVR 583
+ P T + + SE L + P L +P+
Sbjct: 482 QVTTSTEASSSPPTAEVNS-MPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPV---- 536
Query: 584 KSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSSS 618
+ + ST P+ S+PT+ PS S+
Sbjct: 537 -DTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGST 570
Score = 32.7 bits (73), Expect = 1.2
Identities = 67/332 (20%), Positives = 119/332 (35%), Gaps = 35/332 (10%)
Query: 214 SAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEEF 273
S+ PT G T ++ + NSE + T P+ T +A +P E
Sbjct: 2680 SSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGT 2739
Query: 274 PKR--EDQEGSPPETSLPYKWV----VEAANLLIPAVGSSLSEALDLIESDPDAWCDLSK 327
R +GS P TS+ + EA+ + AV +S+ S +++
Sbjct: 2740 SMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVT- 2798
Query: 328 FDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHT-ISDLSRSSR 386
+P +E S L + +H + P T + T S ++
Sbjct: 2799 -SMPTSTPSETS--TPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE 2855
Query: 387 GELIPISPSTEVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCNSLTPKSTPV 446
G ++PIS ++E G + + + P V+ +PV + S S TP T +
Sbjct: 2856 GIVVPISTASE-GSTLLTSIP----------VSTTPVASSEASTL------STTPVDTSI 2898
Query: 447 KTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDK------TPLHQKH 500
+ + ++ + +PS STP+ S +V T P+ + TP+ +
Sbjct: 2899 PVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTS-ILVSTVPVAGSEASTLSTTPVDTRT 2957
Query: 501 AAFVTPDQKYSMDNTPHTPTPFKNALEKYGPL 532
+ + S T P E+ PL
Sbjct: 2958 PVTTSAEASSSPTTAEGTSMPISTPGERRTPL 2989
Score = 31.6 bits (70), Expect = 2.6
Identities = 94/426 (22%), Positives = 150/426 (35%), Gaps = 49/426 (11%)
Query: 218 TEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPI--GTDLDAVRTPEPLEEFPK 275
T +GS L S+P + + E + T P+ T++ + T P
Sbjct: 2509 TASEGSTLLT--SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPT 2566
Query: 276 REDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPS 335
EGS P S+P A++ + + ++ + S + + D S
Sbjct: 2567 STYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPIS 2626
Query: 336 AEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELIPISPS 395
++ SL + S +P A S T +D T+ S + SP+
Sbjct: 2627 TPSEVSTSLTSILVS----TMPVASSEASTLSTTP--VDTRTLVTTSTGTSS-----SPT 2675
Query: 396 TEVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCN-SLTP--KSTPVKTLPFS 452
T G S + P +R L+ + ++T L+ ++ S TP STPV T +
Sbjct: 2676 TAEGSSMPTSTPG------ERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEA 2729
Query: 453 PSQFLNFWNKQDTLELESPSLTSTPVCSQKV----VVTTPLHRDKTPLHQKHAAFVTPDQ 508
S + ++ + +PS STP+ S V V ++ T T +
Sbjct: 2730 SSSPTTA--EGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTE 2787
Query: 509 KYSMDNTPH-TPTPFKNALEKYGPLKPLP--QTPHLEEDLKEVLRSEAG-IELIIEDDIR 564
S T T P E PL +P TP V SEAG + D
Sbjct: 2788 ASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTP--------VASSEAGTLSTTPVDTST 2839
Query: 565 PEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSSSLTLSGI 624
P K SP + + E STL S+ + TT ++S + TLS
Sbjct: 2840 PVTTSTKAS--SSPTTAEGIVVPISTASEG-----STLLTSIPVSTTPVASSEASTLSTT 2892
Query: 625 KEDNSL 630
D S+
Sbjct: 2893 PVDTSI 2898
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 42.0 bits (97), Expect = 0.002
Identities = 93/470 (19%), Positives = 151/470 (32%), Gaps = 72/470 (15%)
Query: 217 PTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKR 276
PT + + T P T KE + + A TT K+ P A TP+ +
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 464
Query: 277 EDQEGSP--PETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDL---- 330
+ +P P + P + L P L+ + P+ + +L
Sbjct: 465 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA------PTTPEKPAPTTPEELAPTT 518
Query: 331 PEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELI 390
PEEP+ + + A + P P P+ T + + ++ E
Sbjct: 519 PEEPTP------TTPEEPAPTTPKAAAPNTPKEPAPT---------TPKEPAPTTPKEPA 563
Query: 391 PISPSTEVGGSGIGTPPSVLKR------QRKRRVALSPVTENSTSLSFLDSCNSLTPKST 444
P +P + GT P+ LK ++ L+P T + + D TPK T
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623
Query: 445 -------PVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLH 497
P T P P+ TL+ +P+ P + TT + T
Sbjct: 624 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT---KGPTSTT 680
Query: 498 QKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIEL 557
A TP K + TP P P P KP P TP + +
Sbjct: 681 SDKPAPTTP--KETAPTTPKEPAPTT-------PKKPAPTTPETPPPTTSEVST------ 725
Query: 558 IIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSS 617
P K + +SP + + A E + PK +PTT ++
Sbjct: 726 -------PTTTKEPTTIHKSPDESTPELSA-----EPTPKALENSPKEPGVPTTKTPAAT 773
Query: 618 SLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMSSAWKTVA 667
++ +D + + L+ PE A K T ++ K A
Sbjct: 774 KPEMTTTAKDKT--TERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 821
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 42.0 bits (97), Expect = 0.002
Identities = 93/470 (19%), Positives = 151/470 (32%), Gaps = 72/470 (15%)
Query: 217 PTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKR 276
PT + + T P T KE + + A TT K+ P A TP+ +
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 505
Query: 277 EDQEGSP--PETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDL---- 330
+ +P P + P + L P L+ + P+ + +L
Sbjct: 506 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA------PTTPEKPAPTTPEELAPTT 559
Query: 331 PEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELI 390
PEEP+ + + A + P P P+ T + + ++ E
Sbjct: 560 PEEPTP------TTPEEPAPTTPKAAAPNTPKEPAPT---------TPKEPAPTTPKEPA 604
Query: 391 PISPSTEVGGSGIGTPPSVLKR------QRKRRVALSPVTENSTSLSFLDSCNSLTPKST 444
P +P + GT P+ LK ++ L+P T + + D TPK T
Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664
Query: 445 -------PVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLH 497
P T P P+ TL+ +P+ P + TT + T
Sbjct: 665 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT---KGPTSTT 721
Query: 498 QKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIEL 557
A TP K + TP P P P KP P TP + +
Sbjct: 722 SDKPAPTTP--KETAPTTPKEPAPTT-------PKKPAPTTPETPPPTTSEVST------ 766
Query: 558 IIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSS 617
P K + +SP + + A E + PK +PTT ++
Sbjct: 767 -------PTTTKEPTTIHKSPDESTPELSA-----EPTPKALENSPKEPGVPTTKTPAAT 814
Query: 618 SLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMSSAWKTVA 667
++ +D + + L+ PE A K T ++ K A
Sbjct: 815 KPEMTTTAKDKT--TERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 862
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 42.0 bits (97), Expect = 0.002
Identities = 93/470 (19%), Positives = 151/470 (32%), Gaps = 72/470 (15%)
Query: 217 PTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKR 276
PT + + T P T KE + + A TT K+ P A TP+ +
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 557
Query: 277 EDQEGSP--PETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDL---- 330
+ +P P + P + L P L+ + P+ + +L
Sbjct: 558 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA------PTTPEKPAPTTPEELAPTT 611
Query: 331 PEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELI 390
PEEP+ + + A + P P P+ T + + ++ E
Sbjct: 612 PEEPTP------TTPEEPAPTTPKAAAPNTPKEPAPT---------TPKEPAPTTPKEPA 656
Query: 391 PISPSTEVGGSGIGTPPSVLKR------QRKRRVALSPVTENSTSLSFLDSCNSLTPKST 444
P +P + GT P+ LK ++ L+P T + + D TPK T
Sbjct: 657 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716
Query: 445 -------PVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLH 497
P T P P+ TL+ +P+ P + TT + T
Sbjct: 717 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT---KGPTSTT 773
Query: 498 QKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIEL 557
A TP K + TP P P P KP P TP + +
Sbjct: 774 SDKPAPTTP--KETAPTTPKEPAPTT-------PKKPAPTTPETPPPTTSEVST------ 818
Query: 558 IIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSS 617
P K + +SP + + A E + PK +PTT ++
Sbjct: 819 -------PTTTKEPTTIHKSPDESTPELSA-----EPTPKALENSPKEPGVPTTKTPAAT 866
Query: 618 SLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMSSAWKTVA 667
++ +D + + L+ PE A K T ++ K A
Sbjct: 867 KPEMTTTAKDKT--TERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 914
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 42.0 bits (97), Expect = 0.002
Identities = 93/470 (19%), Positives = 151/470 (32%), Gaps = 72/470 (15%)
Query: 217 PTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKR 276
PT + + T P T KE + + A TT K+ P A TP+ +
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 598
Query: 277 EDQEGSP--PETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDL---- 330
+ +P P + P + L P L+ + P+ + +L
Sbjct: 599 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA------PTTPEKPAPTTPEELAPTT 652
Query: 331 PEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELI 390
PEEP+ + + A + P P P+ T + + ++ E
Sbjct: 653 PEEPTP------TTPEEPAPTTPKAAAPNTPKEPAPT---------TPKEPAPTTPKEPA 697
Query: 391 PISPSTEVGGSGIGTPPSVLKR------QRKRRVALSPVTENSTSLSFLDSCNSLTPKST 444
P +P + GT P+ LK ++ L+P T + + D TPK T
Sbjct: 698 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 757
Query: 445 -------PVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLH 497
P T P P+ TL+ +P+ P + TT + T
Sbjct: 758 APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT---KGPTSTT 814
Query: 498 QKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIEL 557
A TP K + TP P P P KP P TP + +
Sbjct: 815 SDKPAPTTP--KETAPTTPKEPAPTT-------PKKPAPTTPETPPPTTSEVST------ 859
Query: 558 IIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMSTLPKSLSLPTTAPSNSS 617
P K + +SP + + A E + PK +PTT ++
Sbjct: 860 -------PTTTKEPTTIHKSPDESTPELSA-----EPTPKALENSPKEPGVPTTKTPAAT 907
Query: 618 SLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMSSAWKTVA 667
++ +D + + L+ PE A K T ++ K A
Sbjct: 908 KPEMTTTAKDKT--TERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 955
>gi|89044853 PREDICTED: similar to telomeric repeat binding factor
(NIMA-interacting) 1 [Homo sapiens]
Length = 405
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 23 PEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASH--FPNRTDQQCQYRW 73
PE+ ++ + W EED+ LR+ VR++G+ +W + H F NRT + RW
Sbjct: 338 PEKHQARKRQAWLQEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVTLKDRW 390
Score = 33.1 bits (74), Expect = 0.90
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
Query: 86 WTKEEDQKVIELVKKYGTKQWTLIAKHLK--GRLGKQCRERWHNHLNPEVKKSCWTEEE 142
W +EED+ + V+KYG W+ I H K R ++RW ++K C E+
Sbjct: 349 WLQEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVTLKDRWRT--TKKLKLICSDSED 405
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/212 (22%), Positives = 95/212 (44%), Gaps = 33/212 (15%)
Query: 133 VKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFLSE 192
V+ S WTEEE + + G WA IAKM+ +++ KN + KR+ + L +
Sbjct: 623 VETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFY-FNYKRRHNLDNLLQQ 681
Query: 193 SKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSK 252
K S +P E + ++ SV T+ +E+ + E +++
Sbjct: 682 HKQ----------------KTSRKPREERD--VSQCESVASTVSAQEDEDIE----ASNE 719
Query: 253 EQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAA-----NLLIPAVGSS 307
E+ P ++++AV+ P E+ P+ G+ E ++ + E A +L +P+ +
Sbjct: 720 EENPEDSEVEAVK---PSEDSPENATSRGN-TEPAVELEPTTETAPSTSPSLAVPSTKPA 775
Query: 308 LSEALDLIESDPDAWCDLSKFDL-PEEPSAED 338
E+++ +D + + D+ +E SAE+
Sbjct: 776 EDESVETQVNDSISAETAEQMDVDQQEHSAEE 807
Score = 31.6 bits (70), Expect = 2.6
Identities = 74/370 (20%), Positives = 126/370 (34%), Gaps = 67/370 (18%)
Query: 238 EENSEEELAAATTSK--EQEPIGTDLDAVRTPEPLEEFPKREDQ-------------EGS 282
EEN AA + + EQ+ + + +V+ FP + Q +G
Sbjct: 1850 EENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGP 1909
Query: 283 PPETSLPY------KWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSA 336
PP++ K + AAN + + ++ D E + S +
Sbjct: 1910 PPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSHRYETP 1969
Query: 337 EDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELIPISPST 396
D+I + Q+ L QP + + E +D +R G L P
Sbjct: 1970 SDAIEVISPASSPAPPQEKLQTYQPEVVKANQAE--------NDPTRQYEGPLHHYRPQQ 2021
Query: 397 EVGGSGIGTPPSV-------LKRQRKRRVALSPVTENSTSLSFLDSCNSLTPKSTPVKTL 449
E PPS + R + + + T + +S TP+ P T
Sbjct: 2022 ESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTF 2081
Query: 450 PFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKHAAFVTPD-- 507
SPS +L STPV ++ +P + ++ HQ+ + V+P+
Sbjct: 2082 QNSPS-----------------ALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENL 2124
Query: 508 -QKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIELIIEDDIRPE 566
K +P + E Y P+ P PQ P + E +L L+ + P
Sbjct: 2125 VDKSRGSRPGKSPERSHVSSEPYEPISP-PQVPVVHEKQDSLL-------LLSQRGAEPA 2176
Query: 567 KQK---RKPG 573
+Q+ R PG
Sbjct: 2177 EQRNDARSPG 2186
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 41.2 bits (95), Expect = 0.003
Identities = 76/328 (23%), Positives = 120/328 (36%), Gaps = 56/328 (17%)
Query: 229 PSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEE---FPKREDQEGSPPE 285
P PP + + E + + E+ P +A+ PLEE P E+ SPP
Sbjct: 448 PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPP 507
Query: 286 TSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLV 345
S P+ + E+ L P S S AL+ S P + S P E S L
Sbjct: 508 ESSPFSPLEESP--LSPPEESPPSPALETPLSPPP---EASPLSPPFEESPLSPPPEELP 562
Query: 346 QLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSR----GELIPISPSTEVGGS 401
++ PP + S + P E +S +SR E P+SP E S
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEE-----SPMSPPPEASRLFPPFEESPLSPPPE--ES 615
Query: 402 GIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWN 461
+ PP + LSP E+S P S P + P SP ++ +
Sbjct: 616 PLSPPPEASR--------LSPPPEDS-------------PMSPPPEESPMSPPPEVSRLS 654
Query: 462 KQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKHAAFVTPDQKYS-----MDNTP 516
+ SP +P+ +P + A+ ++P + S +++P
Sbjct: 655 PLPVVSRLSPPPEESPL--------SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
Query: 517 HTPTPFKNALE---KYGPLKPLPQTPHL 541
+P P + + + PL PLP+ P L
Sbjct: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQL 734
Score = 38.1 bits (87), Expect = 0.028
Identities = 96/437 (21%), Positives = 143/437 (32%), Gaps = 64/437 (14%)
Query: 217 PTEGQGSLLTNWPSVPPTIKEEENSEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKR 276
P E S P PP + E + + E+ P +A R P EE P
Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPM- 581
Query: 277 EDQEGSPPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSA 336
SPP P EA+ L P S LS + ES + S+ P E S
Sbjct: 582 -----SPPPEESPMSPPPEASRLFPPFEESPLSPPPE--ESPLSPPPEASRLSPPPEDSP 634
Query: 337 EDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELIPISPST 396
+ + PP + S L P RL S E P+SP
Sbjct: 635 ---------MSPPPEESPMSPPPEVSRLSPLPVVSRL----------SPPPEESPLSPPP 675
Query: 397 EVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQF 456
E + S L + P ++ S DS SL + +P+ LP P
Sbjct: 676 EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLC 735
Query: 457 LNFWNKQDTLELESPSLTS----------------TPVCSQKVVVTTPLHRDKTPLHQKH 500
+ E P L+ +P + + P +P Q
Sbjct: 736 PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP--QAE 793
Query: 501 AAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIELIIE 560
++P Q + +P T P + + + L P P+ HL +E S E +
Sbjct: 794 GPHLSP-QPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLS 852
Query: 561 DDI-------RPEKQKRKPGLRRSPIK----------KVRKSLALDIVDEDVKLMMSTLP 603
++ RPEK +PG +P + + L + E + +S LP
Sbjct: 853 PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP 912
Query: 604 KSLSL-PTTAPSNSSSL 619
+ L L P+ PS S L
Sbjct: 913 EELPLSPSGEPSLSPQL 929
Score = 36.2 bits (82), Expect = 0.11
Identities = 51/219 (23%), Positives = 77/219 (35%), Gaps = 16/219 (7%)
Query: 331 PEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLSRSSRGELI 390
PE+P E Q A + + PP +L P + E L LS E +
Sbjct: 864 PEKPPEEPG------QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP--EEL 915
Query: 391 PISPSTEVGGSGIGTPPSVLKRQRKRRV------ALSPVTENSTSLSFLDSCNSLTPKST 444
P+SPS E S PP L + ALSP+ E + +P +
Sbjct: 916 PLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA 975
Query: 445 PVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKHAAFV 504
P+ P SP N + + + P +PV ++ PL +PL Q + V
Sbjct: 976 PILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH--SLV 1033
Query: 505 TPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEE 543
+ S + P P + L G + + L E
Sbjct: 1034 PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072
>gi|169212925 PREDICTED: similar to telomeric repeat binding factor
(NIMA-interacting) 1 [Homo sapiens]
Length = 405
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 23 PEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASH--FPNRTDQQCQYRW 73
PE+ ++ + W EED+ LR+ +R++G+ +W + H F NRT + RW
Sbjct: 338 PEKHQARKRQAWLQEEDKNLRSGMRKYGEGNWSKILLHYKFNNRTSVTLKDRW 390
Score = 32.0 bits (71), Expect = 2.0
Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
Query: 86 WTKEEDQKVIELVKKYGTKQWTLIAKHLK--GRLGKQCRERWHNHLNPEVKKSCWTEEE 142
W +EED+ + ++KYG W+ I H K R ++RW ++K C E+
Sbjct: 349 WLQEEDKNLRSGMRKYGEGNWSKILLHYKFNNRTSVTLKDRWRT--TKKLKLICSDSED 405
>gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo
sapiens]
Length = 439
Score = 40.8 bits (94), Expect = 0.004
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 23 PEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASH--FPNRTDQQCQYRW 73
PE+ ++ + W EED+ LR+ VR++G+ +W + H F NRT + RW
Sbjct: 372 PEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRW 424
Score = 31.6 bits (70), Expect = 2.6
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 86 WTKEEDQKVIELVKKYGTKQWTLIAKHLK--GRLGKQCRERW 125
W EED+ + V+KYG W+ I H K R ++RW
Sbjct: 383 WLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRW 424
>gi|189409140 telomeric repeat binding factor 1 isoform 2 [Homo
sapiens]
Length = 419
Score = 40.8 bits (94), Expect = 0.004
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 23 PEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASH--FPNRTDQQCQYRW 73
PE+ ++ + W EED+ LR+ VR++G+ +W + H F NRT + RW
Sbjct: 352 PEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRW 404
Score = 31.6 bits (70), Expect = 2.6
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 86 WTKEEDQKVIELVKKYGTKQWTLIAKHLK--GRLGKQCRERW 125
W EED+ + V+KYG W+ I H K R ++RW
Sbjct: 363 WLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRW 404
>gi|5032169 telomeric repeat binding factor 2 [Homo sapiens]
Length = 500
Score = 39.7 bits (91), Expect = 0.010
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 11 DELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASHFP--NRTDQQ 68
DEL D + K KWT EE E ++A V+++G+ +W ++ ++P NRT
Sbjct: 427 DELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVM 486
Query: 69 CQYRW 73
+ RW
Sbjct: 487 IKDRW 491
Score = 30.8 bits (68), Expect = 4.5
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 83 KGPWTKEEDQKVIELVKKYGTKQWTLIAKH--LKGRLGKQCRERW 125
K WT EE + V V+KYG W I+K+ R ++RW
Sbjct: 447 KQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRW 491
>gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]
Length = 828
Score = 38.1 bits (87), Expect = 0.028
Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Query: 111 KHLKGRLGKQCRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDN 170
K++K L K + H+ P WT EE + + G RW +I+K++ RT
Sbjct: 95 KYMKS-LQKTAKIMVHSPTKPASYSVKWTIEEKELFEQGLAKFGRRWTKISKLIGSRTVL 153
Query: 171 AVKNHWNSTIKRKVDTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPS 230
VK++ K KV G E+ + K L ++ EDK G ++ P+ +G N +
Sbjct: 154 QVKSYARQYFKNKVKC-GLDKETPNQKTGHNLQVKNEDK-GTKAWTPSCLRGRADPNLNA 211
Query: 231 VPPTIKEEENSEEE 244
V K E+ S++E
Sbjct: 212 V----KIEKLSDDE 221
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 36.6 bits (83), Expect = 0.081
Identities = 109/490 (22%), Positives = 182/490 (37%), Gaps = 63/490 (12%)
Query: 217 PTEGQGSLLTN--WPSVPPTIKEEEN----SEEELAAA---TTSKEQE---PIGTDLDAV 264
PTE + +L+ + WP+ + +N +E E+A A T KE E PI DL
Sbjct: 309 PTEKEVALVKDVRWPT-ETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPS 367
Query: 265 RTPEPLEEFPKREDQEGSPPETSL-PYKWV-VEAANLLIPAVGSSLSEALDLIESDPDAW 322
+ P +E K+E + SP + L P K + N ++PA L +++ +++
Sbjct: 368 KDMGPPKE-NKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQAN---- 422
Query: 323 CDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQPSALVPSVTEYRLDGHTISDLS 382
E SAE +S ++ + + P + + D++
Sbjct: 423 ---DIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMA 479
Query: 383 RSSRGELIP---ISPST--EVGGSGIGTPPSVLKRQRKRRVALSPVTENSTSLSFL---D 434
+ E+ P ++PST EVG +P S + + V P TE + +
Sbjct: 480 QLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPE 539
Query: 435 SCNSLTPKSTP-VKT-LPFSPSQFLNFWNK----QDTLELESPSLTSTPVCSQKVVVTTP 488
+LT P +KT P + L N +D L T P+ ++ T
Sbjct: 540 MEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQK 599
Query: 489 LHRDKTPLHQ-----KHAA---FVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTP- 539
+ + L + AA ++P+ P + LEK G KP P
Sbjct: 600 GISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPS 659
Query: 540 HLEEDLKEVLRSEAGIELI--IEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKL 597
L + + R E G ++ +DI K P SP KK K LA +
Sbjct: 660 ELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPP---SPEKKT-KPLAT------TQP 709
Query: 598 MMSTLPKSLSLPTTAPSNSSSLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPR-----SH 652
++ K+ + PT+ P + T+ G+ + L G + A P K R S
Sbjct: 710 AKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK 769
Query: 653 FTTPAPMSSA 662
P P++ A
Sbjct: 770 DVKPKPIADA 779
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,494,823
Number of Sequences: 37866
Number of extensions: 1661917
Number of successful extensions: 5353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 127
Number of HSP's that attempted gapping in prelim test: 5004
Number of HSP's gapped (non-prelim): 379
length of query: 700
length of database: 18,247,518
effective HSP length: 109
effective length of query: 591
effective length of database: 14,120,124
effective search space: 8344993284
effective search space used: 8344993284
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.