Guide to the Human Genome
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Search of human proteins with 4505241

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505241 Mpv17 protein [Homo sapiens]
         (176 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505241 Mpv17 protein [Homo sapiens]                               368   e-102
gi|8923892 peroxisomal membrane protein 2, 22kDa [Homo sapiens]        80   9e-16
gi|190358477 MPV17 mitochondrial membrane protein-like isoform 1...    80   1e-15
gi|116235468 MPV17 mitochondrial membrane protein-like 2 [Homo s...    75   3e-14
gi|190360560 MPV17 mitochondrial membrane protein-like isoform 2...    52   2e-07
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]        29   2.4  
gi|154816172 transmembrane protein 170B [Homo sapiens]                 28   5.4  
gi|118026927 nudix (nucleoside diphosphate linked moiety X)-type...    27   9.2  

>gi|4505241 Mpv17 protein [Homo sapiens]
          Length = 176

 Score =  368 bits (945), Expect = e-102
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 1   MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG 60
           MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG
Sbjct: 1   MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCG 60

Query: 61  FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW 120
           FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW
Sbjct: 61  FVGPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNW 120

Query: 121 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL 176
           AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL
Sbjct: 121 AKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSWKAHRL 176


>gi|8923892 peroxisomal membrane protein 2, 22kDa [Homo sapiens]
          Length = 195

 Score = 80.1 bits (196), Expect = 9e-16
 Identities = 50/168 (29%), Positives = 85/168 (50%), Gaps = 5/168 (2%)

Query: 7   YQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQR----GRTLTMVSLGCGFV 62
           Y   L  +P   +  T+G L  LG+ ++Q ++E++  +E+ R    G  L     G  F 
Sbjct: 25  YLLFLRLYPVLTKAATSGILSALGNFLAQ-MIEKKRKKENSRSLDVGGPLRYAVYGFFFT 83

Query: 63  GPVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNWAK 122
           GP+   +Y  ++ +IP    +  L+++LLD+  FAP FL  F  ++  L G  A    AK
Sbjct: 84  GPLSHFFYFFMEHWIPPEVPLAGLRRLLLDRLVFAPAFLMLFFLIMNFLEGKDASAFAAK 143

Query: 123 LQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLS 170
           ++  +  AL  N+ +W  +Q  N   VPL +R+      A+ W +YL+
Sbjct: 144 MRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLA 191


>gi|190358477 MPV17 mitochondrial membrane protein-like isoform 1
           [Homo sapiens]
          Length = 196

 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 50/166 (30%), Positives = 75/166 (45%), Gaps = 6/166 (3%)

Query: 4   WRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCGFVG 63
           W A  RA   HPW   VL  GSL+  GD + Q+L  R       R     +V+    F  
Sbjct: 5   WPALSRAARRHPWPTNVLLYGSLVSAGDALQQRLQGREANWRQTRRVATLVVTFHANFNY 64

Query: 64  PVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCFLPLVGALNGLSAQDNWAKL 123
                W ++L+R +PG      L K+L DQ   AP  +  F   +  L G    D +  L
Sbjct: 65  V----WLRLLERALPGRAPHALLAKLLCDQVVGAPIAVSAFYVGMSILQG--KDDIFLDL 118

Query: 124 QRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYL 169
           ++ + +  ++    WP VQL NF LVP+ +R A       +W +++
Sbjct: 119 KQKFWNTYLSGLMYWPFVQLTNFSLVPVQWRTAYAGVCGFLWATFI 164


>gi|116235468 MPV17 mitochondrial membrane protein-like 2 [Homo
           sapiens]
          Length = 206

 Score = 75.1 bits (183), Expect = 3e-14
 Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 13/184 (7%)

Query: 4   WRAYQRALAAHPWKVQ--------VLTAGSLMGLGDIISQQL-VERRGLQEHQRGRTLTM 54
           WR  +R L+A     Q         L  G+LM  GD + Q   +  R  Q     R+ +M
Sbjct: 6   WRRLRRLLSAGQLLFQGRALLVTNTLGCGALMAAGDGVRQSWEIRARPGQVFDPRRSASM 65

Query: 55  VSLGCGFVGPVVGGWYKVLDRFIPGTTK---VDALKKMLLDQGGFAPCFLGCFLPLVGAL 111
            ++GC  +GP +  WY  LDR  P +      + LKK+L+DQ   +P     +   +G L
Sbjct: 66  FAVGCS-MGPFLHYWYLSLDRLFPASGLRGFPNVLKKVLVDQLVASPLLGVWYFLGLGCL 124

Query: 112 NGLSAQDNWAKLQRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVIWNSYLSW 171
            G +  ++  +L+  + +    ++ +WPA Q  NF  VP  +R+  +  + + W++YLS+
Sbjct: 125 EGQTVGESCQELREKFWEFYKADWCVWPAAQFVNFLFVPPQFRVTYINGLTLGWDTYLSY 184

Query: 172 KAHR 175
             +R
Sbjct: 185 LKYR 188


>gi|190360560 MPV17 mitochondrial membrane protein-like isoform 2
           [Homo sapiens]
          Length = 147

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 4   WRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEHQRGRTLTMVSLGCGFVG 63
           W A  RA   HPW   VL  GSL+  GD + Q+L  R       R     +V+    F  
Sbjct: 5   WPALSRAARRHPWPTNVLLYGSLVSAGDALQQRLQGREANWRQTRRVATLVVTFHANFNY 64

Query: 64  PVVGGWYKVLDRFIPGTTKVDALKKMLLDQGGFAPCFLGCF 104
                W ++L+R +PG      L K+L DQ   AP  +  F
Sbjct: 65  V----WLRLLERALPGRAPHALLAKLLCDQVVGAPIAVSAF 101


>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
          Length = 5183

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 21/107 (19%)

Query: 7    YQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQEH------QRGRTL-TMVSLGC 59
            YQ+ + +  WKV +   G L  +G++I++++     L+E       Q+G  L ++  L  
Sbjct: 4187 YQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLS 4246

Query: 60   GF--------------VGPVVGGWYKVLDRFIPGTTKVDALKKMLLD 92
             F              VG V+ G+  +    +  T  +D  + MLL+
Sbjct: 4247 SFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLE 4293


>gi|154816172 transmembrane protein 170B [Homo sapiens]
          Length = 132

 Score = 27.7 bits (60), Expect = 5.4
 Identities = 9/25 (36%), Positives = 18/25 (72%)

Query: 43 LQEHQRGRTLTMVSLGCGFVGPVVG 67
          LQ H++GR ++++++  GF+  V G
Sbjct: 61 LQRHRQGRVISVIAVSIGFLASVTG 85


>gi|118026927 nudix (nucleoside diphosphate linked moiety X)-type
          motif 18 [Homo sapiens]
          Length = 323

 Score = 26.9 bits (58), Expect = 9.2
 Identities = 11/29 (37%), Positives = 17/29 (58%)

Query: 67 GGWYKVLDRFIPGTTKVDALKKMLLDQGG 95
          G WY    R  PG T V+AL++ + ++ G
Sbjct: 69 GSWYLPAGRMEPGETIVEALQREVKEEAG 97


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,594,417
Number of Sequences: 37866
Number of extensions: 254611
Number of successful extensions: 641
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 628
Number of HSP's gapped (non-prelim): 8
length of query: 176
length of database: 18,247,518
effective HSP length: 95
effective length of query: 81
effective length of database: 14,650,248
effective search space: 1186670088
effective search space used: 1186670088
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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