Guide to the Human Genome
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Search of human proteins with 4504577

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504577 indoleamine 2,3-dioxygenase 1 [Homo sapiens]
         (403 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504577 indoleamine 2,3-dioxygenase 1 [Homo sapiens]               818   0.0  
gi|148539554 indoleamine-pyrrole 2,3 dioxygenase-like 1 [Homo sa...   338   7e-93
gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens]                33   0.46 
gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens]                 33   0.46 
gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens]                 33   0.46 
gi|19923191 minichromosome maintenance complex component 3 assoc...    30   3.0  
gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens]       29   6.6  
gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens]        29   6.6  
gi|62988331 hypothetical protein LOC55780 [Homo sapiens]               29   8.6  

>gi|4504577 indoleamine 2,3-dioxygenase 1 [Homo sapiens]
          Length = 403

 Score =  818 bits (2114), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE 60
           MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
Sbjct: 1   MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE 60

Query: 61  KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL 120
           KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL
Sbjct: 61  KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL 120

Query: 121 PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV 180
           PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV
Sbjct: 121 PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV 180

Query: 181 IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN 240
           IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN
Sbjct: 181 IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN 240

Query: 241 PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP 300
           PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP
Sbjct: 241 PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP 300

Query: 301 PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ 360
           PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
Sbjct: 301 PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ 360

Query: 361 QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG 403
           QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
Sbjct: 361 QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG 403


>gi|148539554 indoleamine-pyrrole 2,3 dioxygenase-like 1 [Homo
           sapiens]
          Length = 420

 Score =  338 bits (866), Expect = 7e-93
 Identities = 172/390 (44%), Positives = 248/390 (63%), Gaps = 5/390 (1%)

Query: 13  KEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTD 72
           + YHI EE GF LP+  + LPD Y  WM IA  LP LI++ QL+  V+K+ +LS   L  
Sbjct: 30  ESYHISEEYGFLLPDSLKELPDHYRPWMEIANKLPQLIDAHQLQAHVDKMPLLSCQFLKG 89

Query: 73  HKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLA 132
           H+ QRLA LVL  +TM YVW +G     +VLPRN+A+P+ ++S+ L LPPILV++D VL 
Sbjct: 90  HREQRLAHLVLSFLTMGYVWQEGEAQPAEVLPRNLALPFVEVSRNLGLPPILVHSDLVLT 149

Query: 133 NWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQE 192
           NW KKDP+  L   N++ + SF  G+   GF LV+ LVE  A   IK +     A+    
Sbjct: 150 NWTKKDPDGFLEIGNLETIISFPGGESLHGFILVTALVEKEAVPGIKALVQATNAILQPN 209

Query: 193 RDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGF 252
           ++ LL+AL  +   ++   +   Q+HD+V+P  F++ +RI+LSGWK NP +  GL+YEG 
Sbjct: 210 QEALLQALQRLRLSIQDITKTLGQMHDYVDPDIFYAGIRIFLSGWKDNPAMPAGLMYEGV 269

Query: 253 WEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLES 312
            ++P +++GGSA QS+V   FD  LGI+ +   G    FL  MR YMPP+H+ F+  + S
Sbjct: 270 SQEPLKYSGGSAAQSTVLHAFDEFLGIRHSKESG---DFLYRMRDYMPPSHKAFIEDIHS 326

Query: 313 NPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPA--SQQPKENKTSED 370
            PS+R+++LS G   L  AY+ CV+AL  LRSYH+ +VTKY++  A  ++  K N     
Sbjct: 327 APSLRDYILSSGQDHLLTAYNQCVQALAELRSYHITMVTKYLITAAAKAKHGKPNHLPGP 386

Query: 371 PSKLEAKGTGGTDLMNFLKTVRSTTEKSLL 400
           P  L+ +GTGGT +M+FLK+VR  T +S+L
Sbjct: 387 PQALKDRGTGGTAVMSFLKSVRDKTLESIL 416


>gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens]
          Length = 553

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 16/112 (14%)

Query: 253 WEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLES 312
           W  P EF+ G+ G +   +        ++    G+  + LQ++R+++     N  C L  
Sbjct: 219 WSFPYEFSYGADGGAKFLE--------KRLKVSGNQHEELQNVRKHIHSCFTNISCFLLP 270

Query: 313 NPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKE 364
           +P ++       D  L+E  D  +K        +L+I+  ++L P S   KE
Sbjct: 271 HPGLKVATNPNFDGKLKEIDDEFIK--------NLKILIPWLLSPESLDIKE 314


>gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens]
          Length = 553

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 16/112 (14%)

Query: 253 WEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLES 312
           W  P EF+ G+ G +   +        ++    G+  + LQ++R+++     N  C L  
Sbjct: 219 WSFPYEFSYGADGGAKFLE--------KRLKVSGNQHEELQNVRKHIHSCFTNISCFLLP 270

Query: 313 NPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKE 364
           +P ++       D  L+E  D  +K        +L+I+  ++L P S   KE
Sbjct: 271 HPGLKVATNPNFDGKLKEIDDEFIK--------NLKILIPWLLSPESLDIKE 314


>gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens]
          Length = 558

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 16/112 (14%)

Query: 253 WEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLES 312
           W  P EF+ G+ G +   +        ++    G+  + LQ++R+++     N  C L  
Sbjct: 219 WSFPYEFSYGADGGAKFLE--------KRLKVSGNQHEELQNVRKHIHSCFTNISCFLLP 270

Query: 313 NPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKE 364
           +P ++       D  L+E  D  +K        +L+I+  ++L P S   KE
Sbjct: 271 HPGLKVATNPNFDGKLKEIDDEFIK--------NLKILIPWLLSPESLDIKE 314


>gi|19923191 minichromosome maintenance complex component 3
           associated protein [Homo sapiens]
          Length = 1980

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 30  ENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLAR 80
           +N+PD+ ND   +  H   + +  ++  R  K   L++ H  DH S  LAR
Sbjct: 440 KNIPDYLNDRTILENHFGKIAKVQRIFTRRSK--KLAVVHFFDHASAALAR 488


>gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens]
          Length = 431

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 12/56 (21%), Positives = 31/56 (55%)

Query: 344 SYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSL 399
           SY  +++ +Y    A Q   ++ + +  ++ + + +GG+D  +++ T+R    K+L
Sbjct: 282 SYLTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNL 337


>gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens]
          Length = 443

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 12/56 (21%), Positives = 31/56 (55%)

Query: 344 SYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSL 399
           SY  +++ +Y    A Q   ++ + +  ++ + + +GG+D  +++ T+R    K+L
Sbjct: 294 SYLTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNL 349


>gi|62988331 hypothetical protein LOC55780 [Homo sapiens]
          Length = 678

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 14/52 (26%), Positives = 28/52 (53%)

Query: 160 SKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKAL 211
           +KG F +         S  ++ P +F A++  +   +  +L+++ SCLE+AL
Sbjct: 86  TKGQFEIRYAPWFQWTSFPELFPEIFDALESLQSPAISLSLMKLTSCLERAL 137


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,894,447
Number of Sequences: 37866
Number of extensions: 694953
Number of successful extensions: 1416
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1409
Number of HSP's gapped (non-prelim): 9
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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