Guide to the Human Genome
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Name: HBB Sequence: fasta or formatted (147aa) NCBI GI: 4504349
Description:

beta globin

Referenced in:

Major Disease Loci
Oxygen Sensing and Hemoglobin
Polymorphism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.2         15           2
 C cysteine            1.4          2           1
 D aspartate           4.8          7           1
 E glutamate           5.4          8           2
 F phenylalanine       5.4          8           2
 G glycine             8.8         13           2
 H histidine           6.1          9           2
 I isoleucine          0.0          0           0
 K lysine              7.5         11           2
 L leucine            12.2         18           2
 M methionine          1.4          2           1
 N asparagine          4.1          6           1
 P proline             4.8          7           2
 Q glutamine           2.0          3           1
 R arginine            2.0          3           1
 S serine              3.4          5           1
 T threonine           4.8          7           1
 V valine             12.2         18           2
 W tryptophan          1.4          2           1
 Y tyrosine            2.0          3           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   beta globin 
HBD                   0.925   delta globin 
HBE1                  0.761   epsilon globin 
HBG2                  0.743   G-gamma globin 
HBG1                  0.729   A-gamma globin 
HBA1                  0.318   alpha 1 globin 
HBA2                  0.318   alpha 2 globin 
HBZ                   0.261   hemoglobin, zeta 
HBQ1                  0.246   theta 1 globin 
HBM                   0.214   hemoglobin mu chain 
CYGB                  0.164   cytoglobin 
KIAA0802              0.014   hypothetical protein LOC23255 
ARHGAP8               0.011   Rho GTPase activating protein 8 isoform 1 
LRRC18                0.007   leucine rich repeat containing 18 
BDP1                  0.007   transcription factor-like nuclear regulator 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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