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Search of human proteins with 4504097
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504097 G protein-coupled receptor 39 [Homo sapiens]
(453 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504097 G protein-coupled receptor 39 [Homo sapiens] 903 0.0
gi|110611243 neurotensin receptor 1 [Homo sapiens] 177 2e-44
gi|6912538 neurotensin receptor 2 [Homo sapiens] 147 2e-35
gi|170932505 neuromedin U receptor 2 [Homo sapiens] 133 3e-31
gi|4504095 motilin receptor [Homo sapiens] 128 9e-30
gi|188497623 neuromedin U receptor 1 [Homo sapiens] 127 2e-29
gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom... 105 6e-23
gi|4885057 apelin receptor [Homo sapiens] 94 3e-19
gi|169808392 endothelin receptor type B isoform 1 precursor [Hom... 85 1e-16
gi|4557547 endothelin receptor type B isoform 1 precursor [Homo ... 85 1e-16
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 85 2e-16
gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo... 84 3e-16
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 82 8e-16
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 82 1e-15
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 82 1e-15
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 82 1e-15
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 82 1e-15
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 82 1e-15
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 82 1e-15
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 82 1e-15
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] 82 1e-15
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] 82 1e-15
gi|167000885 galanin receptor 1 [Homo sapiens] 81 2e-15
gi|4557857 somatostatin receptor 1 [Homo sapiens] 80 3e-15
gi|4557861 somatostatin receptor 3 [Homo sapiens] 80 3e-15
gi|4503465 endothelin receptor type A [Homo sapiens] 80 4e-15
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 80 5e-15
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 80 5e-15
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 80 5e-15
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 80 5e-15
>gi|4504097 G protein-coupled receptor 39 [Homo sapiens]
Length = 453
Score = 903 bits (2334), Expect = 0.0
Identities = 453/453 (100%), Positives = 453/453 (100%)
Query: 1 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK 60
MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK
Sbjct: 1 MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK 60
Query: 61 KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY 120
KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY
Sbjct: 61 KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY 120
Query: 121 ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL 180
ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL
Sbjct: 121 ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL 180
Query: 181 VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF 240
VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF
Sbjct: 181 VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF 240
Query: 241 MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ 300
MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ
Sbjct: 241 MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ 300
Query: 301 IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC 360
IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC
Sbjct: 301 IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC 360
Query: 361 CRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQ 420
CRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQ
Sbjct: 361 CRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQ 420
Query: 421 SKSQSLSLESLEPNSGAKPANSAAENGFQEHEV 453
SKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
Sbjct: 421 SKSQSLSLESLEPNSGAKPANSAAENGFQEHEV 453
>gi|110611243 neurotensin receptor 1 [Homo sapiens]
Length = 418
Score = 177 bits (449), Expect = 2e-44
Identities = 112/345 (32%), Positives = 175/345 (50%), Gaps = 21/345 (6%)
Query: 22 EFEVATWI--KITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSD 79
E +V T I K+ + VYL +FV+G +GN+ T + LQ V H+ SLA SD
Sbjct: 53 ELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSD 112
Query: 80 ILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICH 139
+L L+ MP+E Y+ IW + C+ + FL +AC+YAT L+V +LS ERY+AICH
Sbjct: 113 LLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICH 172
Query: 140 PFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHH 199
PF+ K + + K I +W+ SAL+A+P+LF MG + + GL C + T H
Sbjct: 173 PFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVC--TPTIH- 229
Query: 200 EQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMK--SQKGSL 257
T+ + + V Q + F +F+ +VV+ + + N + V+++ +++G +
Sbjct: 230 ----TATVKV---------VIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQV 276
Query: 258 AGGTRPPQLRKSESEESRT-ARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTR 316
E R A R + LR +V+ VCW+P +RR+M WT
Sbjct: 277 CTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTP 336
Query: 317 SYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
+ Y + FY+SS INP+LY + S FR +F+ L C
Sbjct: 337 FLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLAC 381
>gi|6912538 neurotensin receptor 2 [Homo sapiens]
Length = 410
Score = 147 bits (371), Expect = 2e-35
Identities = 97/362 (26%), Positives = 167/362 (46%), Gaps = 48/362 (13%)
Query: 28 WIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGM 87
W K+ +Y +I+ +G GN+ ++ V VL+ + + H++SLA + +L+ L+G+
Sbjct: 30 WAKVLFTALYALIWALGAAGNALSVHV--VLKARAGRAGRLRHHVLSLALAGLLLLLVGV 87
Query: 88 PMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVS 147
P+E YS +W L C+ + F+ E C+YAT+L V LS ER +A+C P R +++
Sbjct: 88 PVELYSFVWFHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLL 147
Query: 148 GPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNM 207
P + + L+ W S +ALP+ MG ++ L +PE ++
Sbjct: 148 TPRRTRWLVALSWAASLGLALPMAVIMGQKHELETADG---------------EPEPAS- 191
Query: 208 SICTNLSSRWTV---FQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPP 264
+CT L SR + Q ++ +FV+ L + + + + + L + G+ P
Sbjct: 192 RVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQVPSTSTPGSSTP 251
Query: 265 QLRKSESEES----------------------RTARR-----QTIIFLRLIVVTLAVCWM 297
+ SEE + RR +++ LR IVV +CW+
Sbjct: 252 SRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLRAIVVMYVICWL 311
Query: 298 PNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQ 357
P RR+M P WT + Y + T FY+SS + PLLY S FR++F++
Sbjct: 312 PYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNAVSSSFRKLFLE 371
Query: 358 VL 359
+
Sbjct: 372 AV 373
>gi|170932505 neuromedin U receptor 2 [Homo sapiens]
Length = 415
Score = 133 bits (335), Expect = 3e-31
Identities = 94/343 (27%), Positives = 162/343 (47%), Gaps = 38/343 (11%)
Query: 35 LVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSI 94
+VY+ IFV+G++GN + V V+ + ++ ++ SLA SD+LV L+GMP+E Y +
Sbjct: 50 VVYVPIFVVGVIGN---VLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEM 106
Query: 95 IWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKL 154
W + C T LFE +A++L + T+S ERY+AI HPFR K S +
Sbjct: 107 -WRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALR 165
Query: 155 LIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETS---NMSICT 211
++G VW S L +LP N H + H P S + CT
Sbjct: 166 ILGIVWGFSVLFSLP------------NTSIH--------GIKFHYFPNGSLVPGSATCT 205
Query: 212 NLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSES 271
+ W ++ I ++ ++ ++V + + +M + +K K A + +
Sbjct: 206 VIKPMW-IYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEAD--------EGNA 256
Query: 272 EESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSET 331
R R+ L ++V+ A+CW P I R+ + +W+ S + ++ S
Sbjct: 257 NIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSF--VEEWSESLAAVFNLVHVVSGV 314
Query: 332 FFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRL 374
FFYLSS +NP++Y + S++F+ F V+ H+ H+ +L
Sbjct: 315 FFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQL 357
>gi|4504095 motilin receptor [Homo sapiens]
Length = 412
Score = 128 bits (322), Expect = 9e-30
Identities = 104/375 (27%), Positives = 168/375 (44%), Gaps = 33/375 (8%)
Query: 16 DHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSL 75
D F + + +T + L +FV+G+ GN T+ ++ + ++ ++ S+
Sbjct: 26 DERRCSPFPLGALVPVTAVC--LCLFVVGVSGNVVTV---MLIGRYRDMRTTTNLYLGSM 80
Query: 76 ACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYI 135
A SD+L+ L+G+P + Y + W L C+L ++ E C+YATLLH+ LS ERY+
Sbjct: 81 AVSDLLI-LLGLPFDLYRL-WRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYL 138
Query: 136 AICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYP--LVNVPSHRGLTCNR 193
AIC P R + + +V+ LI +W + L A P LF +G E + VP G
Sbjct: 139 AICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIA 198
Query: 194 SSTRHHEQ---------------PETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSV 238
SS PET+ + + R + Q GA V L V +
Sbjct: 199 SSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQ---LGALRVMLWVTTAY 255
Query: 239 AFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMP 298
F+ + + +L L RP LR + RQT+ L ++V+ +CW+P
Sbjct: 256 FFLPFLCLSILYGLIGRELWSSRRP--LRGPAASGRERGHRQTVRVLLVVVLAFIICWLP 313
Query: 299 NQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQV 358
+ RI+ D YF Y ++ FYLS+ INP+LY + S+++R ++
Sbjct: 314 FHVGRIIYI--NTEDSRMMYFSQYFNIVALQ--LFYLSASINPILYNLISKKYRAAAFKL 369
Query: 359 LCCRLSLQHANHEKR 373
L R S H R
Sbjct: 370 LLARKSRPRGFHRSR 384
>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
Length = 426
Score = 127 bits (319), Expect = 2e-29
Identities = 98/349 (28%), Positives = 162/349 (46%), Gaps = 23/349 (6%)
Query: 27 TWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIG 86
T + + + YL+IFV+G +GN T V +L+ K ++ ++ SLA SD+LV L+G
Sbjct: 57 TELFMPICATYLLIFVVGAVGNGLTCLV--ILRHKA-MRTPTNYYLFSLAVSDLLVLLVG 113
Query: 87 MPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAV 146
+P+E Y + W+ C T LFE A++L+V LS ERY+A+ HP + +++
Sbjct: 114 LPLELYEM-WHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSM 172
Query: 147 SGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSN 206
V+ ++G VW + L +LP G ++VP RG + + N
Sbjct: 173 VTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQ--LHVPC-RGPVPDSAVCMLVRPRALYN 229
Query: 207 MSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQL 266
M + T + + + V+ L + +LM+ KG + R
Sbjct: 230 MVVQTTALLFFCL-------PMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYT 282
Query: 267 RKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILL 326
+ + + RRQ L ++VV +CW P R+M + + WT A+ +
Sbjct: 283 CRLQQHD--RGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQ--WTDGLHLAFQHVH 338
Query: 327 PFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC-----RLSLQHANH 370
S FFYL S NP+LY++ S +FR F + LC RL +H++H
Sbjct: 339 VISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGACCHRLRPRHSSH 387
>gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo
sapiens]
Length = 366
Score = 105 bits (263), Expect = 6e-23
Identities = 87/321 (27%), Positives = 148/321 (46%), Gaps = 36/321 (11%)
Query: 40 IFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPL 99
+FV+G+ GN T+ V ++ L+ ++ S+A SD+L+FL MP++ + W
Sbjct: 53 LFVVGIAGNLLTMLVVSRFRE---LRTTTNLYLSSMAFSDLLIFLC-MPLDLVRL-WQYR 107
Query: 100 TTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFV 159
+ L CKL F+ E+C+YAT+L + LS ERY AIC P R K V +VKL+I +
Sbjct: 108 PWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVI 167
Query: 160 WVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTV 219
W + A P+ +G E+ N + + + ++ + L +
Sbjct: 168 WAVAFCSAGPIFVLVGVEHE------------NGTDPWDTNECRPTEFAVRSGLLTVMVW 215
Query: 220 FQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARR 279
S F V L VL S+ + + L + ++G G LR +
Sbjct: 216 VSSIFFFLPVFCLTVLYSL------IGRKLWRRRRGDAVVGA---SLRDQN-------HK 259
Query: 280 QTIIFLRLIVVTLAVCWMPNQI-RRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSV 338
QT+ L ++V +CW+P + R + + + + Y L+ F FYLS+
Sbjct: 260 QTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSF--VLFYLSAA 317
Query: 339 INPLLYTVSSQQFRRVFVQVL 359
INP+LY + S+++R ++L
Sbjct: 318 INPILYNIMSKKYRVAVFRLL 338
>gi|4885057 apelin receptor [Homo sapiens]
Length = 380
Score = 93.6 bits (231), Expect = 3e-19
Identities = 84/365 (23%), Positives = 150/365 (41%), Gaps = 53/365 (14%)
Query: 8 GSDCSQIIDHSHVPEFEVATWIKITLIL--VYLIIFVMGLLGNSATIRVTQVLQKKGYLQ 65
G D + E E W ++ +Y+++F++G GN + V + +
Sbjct: 4 GGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWT--VFRSSREKR 61
Query: 66 KEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSY-----TLSCKLHTFLFEACSY 120
+ + SLA +D L F++ +P+ W T Y T CKL ++L Y
Sbjct: 62 RSADIFIASLAVAD-LTFVVTLPL------WATYTYRDYDWPFGTFFCKLSSYLIFVNMY 114
Query: 121 ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL 180
A++ + LSF+RY+AI P + + +WV +AL+A+P++ T
Sbjct: 115 ASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTT---- 170
Query: 181 VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWT----VFQSSIFGAFVVYLVVLL 236
G N + + + + S+ +SS W + SS FVV ++L
Sbjct: 171 -------GDLENTTKVQCY-----MDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIML 218
Query: 237 SVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCW 296
+ F ++AG R ++ E RR+ + + ++VVT A+CW
Sbjct: 219 TCYFFIAQ-----------TIAGHFRKERI------EGLRKRRRLLSIIVVLVVTFALCW 261
Query: 297 MPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFV 356
MP + + + W + M + P+ Y++S +NP LY +FR+
Sbjct: 262 MPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACT 321
Query: 357 QVLCC 361
+LCC
Sbjct: 322 SMLCC 326
>gi|169808392 endothelin receptor type B isoform 1 precursor [Homo
sapiens]
Length = 442
Score = 85.1 bits (209), Expect = 1e-16
Identities = 78/340 (22%), Positives = 148/340 (43%), Gaps = 33/340 (9%)
Query: 24 EVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVF 83
E+ K +V ++FV+G++GNS +R+ + K ++ + SLA D+L
Sbjct: 95 EIKETFKYINTVVSCLVFVLGIIGNSTLLRI---IYKNKCMRNGPNILIASLALGDLLHI 151
Query: 84 LIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRY 143
+I +P+ Y ++ + CKL F+ +A T+L + LS +RY A+ R
Sbjct: 152 VIDIPINVYKLLAEDWPFGAEM--CKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRI 209
Query: 144 KAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPE 203
K + P + I +WV S ++A+P A+G + ++ C H +
Sbjct: 210 KGIGVPKWTAVEIVLIWVVSVVLAVP--EAIGFDIITMDYKGSYLRIC-----LLHPVQK 262
Query: 204 TSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRP 263
T+ M W F Y + L++ + +M M +K +
Sbjct: 263 TAFMQFYKTAKDWW---------LFSFYFCLPLAITAFFYTLMTCEMLRKKSGM------ 307
Query: 264 PQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIM-AAAKPKHDWTRSYFRAY 322
Q+ ++ + R +T+ L V+ A+CW+P + RI+ ++D R ++
Sbjct: 308 -QIALNDHLKQRREVAKTVFCL---VLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSF 363
Query: 323 MILLPF-SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
+++L + L+S INP+ + S++F+ F LCC
Sbjct: 364 LLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCC 403
>gi|4557547 endothelin receptor type B isoform 1 precursor [Homo
sapiens]
Length = 442
Score = 85.1 bits (209), Expect = 1e-16
Identities = 78/340 (22%), Positives = 148/340 (43%), Gaps = 33/340 (9%)
Query: 24 EVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVF 83
E+ K +V ++FV+G++GNS +R+ + K ++ + SLA D+L
Sbjct: 95 EIKETFKYINTVVSCLVFVLGIIGNSTLLRI---IYKNKCMRNGPNILIASLALGDLLHI 151
Query: 84 LIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRY 143
+I +P+ Y ++ + CKL F+ +A T+L + LS +RY A+ R
Sbjct: 152 VIDIPINVYKLLAEDWPFGAEM--CKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRI 209
Query: 144 KAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPE 203
K + P + I +WV S ++A+P A+G + ++ C H +
Sbjct: 210 KGIGVPKWTAVEIVLIWVVSVVLAVP--EAIGFDIITMDYKGSYLRIC-----LLHPVQK 262
Query: 204 TSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRP 263
T+ M W F Y + L++ + +M M +K +
Sbjct: 263 TAFMQFYKTAKDWW---------LFSFYFCLPLAITAFFYTLMTCEMLRKKSGM------ 307
Query: 264 PQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIM-AAAKPKHDWTRSYFRAY 322
Q+ ++ + R +T+ L V+ A+CW+P + RI+ ++D R ++
Sbjct: 308 -QIALNDHLKQRREVAKTVFCL---VLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSF 363
Query: 323 MILLPF-SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
+++L + L+S INP+ + S++F+ F LCC
Sbjct: 364 LLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCC 403
>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
Length = 397
Score = 84.7 bits (208), Expect = 2e-16
Identities = 83/373 (22%), Positives = 152/373 (40%), Gaps = 50/373 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QRPLLFASRRQSS 401
R RRQ S
Sbjct: 383 DRTNHQRERRQKS 395
>gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo
sapiens]
Length = 289
Score = 84.0 bits (206), Expect = 3e-16
Identities = 50/139 (35%), Positives = 78/139 (56%), Gaps = 5/139 (3%)
Query: 40 IFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPL 99
+FV+G+ GN T+ V ++ L+ ++ S+A SD+L+FL MP++ + W
Sbjct: 53 LFVVGIAGNLLTMLVVSRFRE---LRTTTNLYLSSMAFSDLLIFLC-MPLDLVRL-WQYR 107
Query: 100 TTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFV 159
+ L CKL F+ E+C+YAT+L + LS ERY AIC P R K V +VKL+I +
Sbjct: 108 PWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVI 167
Query: 160 WVTSALVALPLLFAMGTEY 178
W + A P+ +G E+
Sbjct: 168 WAVAFCSAGPIFVLVGVEH 186
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 82.4 bits (202), Expect = 8e-16
Identities = 76/343 (22%), Positives = 156/343 (45%), Gaps = 29/343 (8%)
Query: 30 KITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDH-MVSLACSDILVFLIGMP 88
K+ L+ + +M +LGN + V + L+K T++ +VSLA +D+LV ++ MP
Sbjct: 19 KVVLLTFLSTVILMAILGN---LLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 89 ---MEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAIC-HPFRYK 144
+E IW + C + T L + A++ H+ +S +RY AIC P Y+
Sbjct: 76 FGAIELVQDIW-----IYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130
Query: 145 AVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPS--HRGLTCNRSSTRHHEQP 202
P ++ L++G WV ++ + ++++ ++GL + + +
Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFN 190
Query: 203 ETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTR 262
+ SN + C + ++ S+ ++ +L+++L+ + + + Q AG +
Sbjct: 191 QNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASS 250
Query: 263 PPQLRKSESEESRTARRQTIIFLRLIVVT--LAVCWMPNQIRRIMAAAKPKHDWT--RSY 318
+ + ++ + R +T L ++ +CW P + I+ P D+T
Sbjct: 251 ESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIV---DPFIDYTVPGQV 307
Query: 319 FRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
+ A++ L Y++S +NP LY ++ FRR F+ +LCC
Sbjct: 308 WTAFLWL-------GYINSGLNPFLYAFLNKSFRRAFLIILCC 343
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 164 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 217
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 218 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 277
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 278 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 312
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 313 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 361
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 362 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 415
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 416 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 475
Query: 389 QR 390
R
Sbjct: 476 DR 477
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QR 390
R
Sbjct: 383 DR 384
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QR 390
R
Sbjct: 383 DR 384
>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
Length = 403
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QR 390
R
Sbjct: 383 DR 384
>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
Length = 406
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QR 390
R
Sbjct: 383 DR 384
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QR 390
R
Sbjct: 383 DR 384
>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
Length = 389
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QR 390
R
Sbjct: 383 DR 384
>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
Length = 418
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QR 390
R
Sbjct: 383 DR 384
>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
Length = 446
Score = 81.6 bits (200), Expect = 1e-15
Identities = 79/362 (21%), Positives = 148/362 (40%), Gaps = 50/362 (13%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
IT++ +Y I+ V+GL GN V V+ + ++ ++ +LA +D L +
Sbjct: 71 ITIMALYSIVCVVGLFGN---FLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLP 124
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPC 150
F S+ + T T+ CK+ + + ++ + T+S +RYIA+CHP + P
Sbjct: 125 FQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184
Query: 151 QVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSIC 210
K++ W+ S+ + LP++F T+Y ++ C
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSID-------------------------C 219
Query: 211 TNLSSRWTVFQSSIFG--AFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRK 268
T S T + ++ F+ ++ + + +C+ +M + +KS + +
Sbjct: 220 TLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVR-----------MLS 268
Query: 269 SESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPF 328
E+ R RR T + L ++V VCW P I I+ A + T + F
Sbjct: 269 GSKEKDRNLRRITRMVL-VVVAVFIVCWTPIHIYVIIKALVTIPETT-----FQTVSWHF 322
Query: 329 SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFV 388
Y +S +NP+LY + F+R F + S + R+R + +A V
Sbjct: 323 CIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTV 382
Query: 389 QR 390
R
Sbjct: 383 DR 384
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 80.9 bits (198), Expect = 2e-15
Identities = 84/349 (24%), Positives = 147/349 (42%), Gaps = 57/349 (16%)
Query: 21 PEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDI 80
P F + +TL+ V+ +IF +G+LGNS I V K G + +++L+ +D+
Sbjct: 25 PLFGIGVENFVTLV-VFGLIFALGVLGNSLVITVL-ARSKPGKPRSTTNLFILNLSIADL 82
Query: 81 LVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHP 140
L +P F + ++ T CK + F ++ + +S +RY+AI H
Sbjct: 83 AYLLFCIP--FQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHS 140
Query: 141 FRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHE 200
R ++ L +G +W S +A P+ + H+GL
Sbjct: 141 RRSSSLRVSRNALLGVGCIWALSIAMASPVAY-------------HQGLF---------- 177
Query: 201 QPETSNMSICTN-----LSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKG 255
P SN + C + V + +FG YL+ LL + F ++ L K K
Sbjct: 178 HPRASNQTFCWEQWPDPRHKKAYVVCTFVFG----YLLPLLLICFCYAKVLNHLHKKLKN 233
Query: 256 SLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWT 315
+KSE+ + +TA QT++ ++VV + W+P+ I + A
Sbjct: 234 ---------MSKKSEASKKKTA--QTVL---VVVVVFGISWLPHHIIHLWAEFGVFPLTP 279
Query: 316 RSY-FRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRL 363
S+ FR L +S +S +NP++Y S+ FR+ + QV C +
Sbjct: 280 ASFLFRITAHCLAYS------NSSVNPIIYAFLSENFRKAYKQVFKCHI 322
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 80.5 bits (197), Expect = 3e-15
Identities = 84/334 (25%), Positives = 146/334 (43%), Gaps = 57/334 (17%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPME 90
I + +Y ++ ++GL GNS I V+ + ++ ++++LA +D L+ L +P
Sbjct: 59 ILISFIYSVVCLVGLCGNSMVI---YVILRYAKMKTATNIYILNLAIADELLML-SVPFL 114
Query: 91 FYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLT-LSFERYIAICHPFRYKAVSGP 149
S + + L C+L +A + T ++ LT LS +RY+A+ HP + P
Sbjct: 115 VTSTLLRHWPFGA--LLCRL-VLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRP 171
Query: 150 CQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSI 209
K++ VWV S LV LP++ T S + CN PE
Sbjct: 172 TVAKVVNLGVWVLSLLVILPIVVFSRTA-----ANSDGTVACNML------MPEP----- 215
Query: 210 CTNLSSRWTVFQSSIFGAFVVYLVV---LLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQL 266
+ RW V FV+Y + LL V +C + ++ K + +L G + Q
Sbjct: 216 ----AQRWLV-------GFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQ--QR 262
Query: 267 RKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILL 326
++SE R+ + + ++V+ +CWMP + +++ + D T S
Sbjct: 263 KRSE--------RKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVS--------- 305
Query: 327 PFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC 360
S Y +S NP+LY S F+R F ++LC
Sbjct: 306 QLSVILGYANSCANPILYGFLSDNFKRSFQRILC 339
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 80.5 bits (197), Expect = 3e-15
Identities = 89/338 (26%), Positives = 154/338 (45%), Gaps = 63/338 (18%)
Query: 31 ITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTD-HMVSLACSDILVFLIGMPM 89
+ + LVYL++ V+GLLGNS I V VL+ VT+ ++++LA +D L F++G+P
Sbjct: 45 VLIPLVYLVVCVVGLLGNSLVIYV--VLRHTA--SPSVTNVYILNLALADEL-FMLGLP- 98
Query: 90 EFYSIIWNPLTTSSY-TLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSG 148
+ N L+ + +L C+L + + ++ + +S +RY+A+ HP R
Sbjct: 99 --FLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRT 156
Query: 149 PCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMS 208
+ + VWV SA+V LP++ G VP RG+ ST H + PE
Sbjct: 157 APVARTVSAAVWVASAVVVLPVVVFSG-------VP--RGM-----STCHMQWPEP---- 198
Query: 209 ICTNLSSRWTVFQSSIFGAFVVYLVVL-----LSVAFMCWNMMQVLMKSQKGSLAGGTR- 262
++ W F++Y L L V +C+ ++ V ++S G R
Sbjct: 199 -----AAAWR-------AGFIIYTAALGFFGPLLVICLCYLLIVVKVRS------AGRRV 240
Query: 263 -PPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRA 321
P ++ E R R + +V +CWMP + I+ P + ++F
Sbjct: 241 WAPSCQRRRRSERRVTR-----MVVAVVALFVLCWMPFYVLNIVNVVCPLPE-EPAFFGL 294
Query: 322 YMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVL 359
Y +++ Y +S NP+LY S +F++ F +VL
Sbjct: 295 YFLVVALP----YANSCANPILYGFLSYRFKQGFRRVL 328
>gi|4503465 endothelin receptor type A [Homo sapiens]
Length = 427
Score = 80.1 bits (196), Expect = 4e-15
Identities = 79/352 (22%), Positives = 159/352 (45%), Gaps = 38/352 (10%)
Query: 17 HSHVPE-FEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSL 75
H++ P+ ++ + K ++ IF++G++GN+ +R+ + Q K ++ + SL
Sbjct: 66 HNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRI--IYQNK-CMRNGPNALIASL 122
Query: 76 ACSDILVFLIGMPMEFYSII---WNPLTTSSY-TLSCKLHTFLFEACSYATLLHVLTLSF 131
A D++ +I +P+ + ++ W P + + CKL FL ++ T+L++ LS
Sbjct: 123 ALGDLIYVVIDLPINVFKLLAGRW-PFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSV 181
Query: 132 ERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTC 191
+RY A+ R + + P + I +W+ S ++A+P A+G + TC
Sbjct: 182 DRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIP--EAIGFVMVPFEYRGEQHKTC 239
Query: 192 NRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMK 251
++T + M ++ W +FG + + + L+ A M ++
Sbjct: 240 MLNAT-------SKFMEFYQDVKDWW------LFGFY--FCMPLVCTAIFYTLMTCEMLN 284
Query: 252 SQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIM-AAAKP 310
+ GSL ++ SE + R +T+ L VV A+CW P + RI+
Sbjct: 285 RRNGSL-------RIALSEHLKQRREVAKTVFCL---VVIFALCWFPLHLSRILKKTVYN 334
Query: 311 KHDWTRSYFRAYMILLPF-SETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
+ D R ++++L+ + ++S INP+ S++F+ F LCC
Sbjct: 335 EMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCC 386
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 79.7 bits (195), Expect = 5e-15
Identities = 76/341 (22%), Positives = 150/341 (43%), Gaps = 39/341 (11%)
Query: 30 KITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDH-MVSLACSDILVFLIGMP 88
K+ L+ + +M +LGN + V + L+K T++ +VSLA +D+LV ++ MP
Sbjct: 19 KVVLLTFLSTVILMAILGN---LLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 89 ---MEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAIC-HPFRYK 144
+E IW + C + T L + A++ H+ +S +RY AIC P Y+
Sbjct: 76 FGAIELVQDIW-----IYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130
Query: 145 AVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPET 204
P ++ L++G WV ++ + ++++ R N
Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN------------ 178
Query: 205 SNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPP 264
SN + C + ++ S+ ++ +L+++L+ + + + Q AG +
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 265 QLRKSESEESRTARRQTIIFLRLIVVT--LAVCWMPNQIRRIMAAAKPKHDWT--RSYFR 320
+ + ++ + R +T L ++ +CW P + I+ P D+T +
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIV---DPFIDYTVPGQVWT 295
Query: 321 AYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
A++ L Y++S +NP LY ++ FRR F+ +LCC
Sbjct: 296 AFLWL-------GYINSGLNPFLYAFLNKSFRRAFLIILCC 329
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 79.7 bits (195), Expect = 5e-15
Identities = 76/341 (22%), Positives = 150/341 (43%), Gaps = 39/341 (11%)
Query: 30 KITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDH-MVSLACSDILVFLIGMP 88
K+ L+ + +M +LGN + V + L+K T++ +VSLA +D+LV ++ MP
Sbjct: 19 KVVLLTFLSTVILMAILGN---LLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 89 ---MEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAIC-HPFRYK 144
+E IW + C + T L + A++ H+ +S +RY AIC P Y+
Sbjct: 76 FGAIELVQDIW-----IYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130
Query: 145 AVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPET 204
P ++ L++G WV ++ + ++++ R N
Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN------------ 178
Query: 205 SNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPP 264
SN + C + ++ S+ ++ +L+++L+ + + + Q AG +
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 265 QLRKSESEESRTARRQTIIFLRLIVVT--LAVCWMPNQIRRIMAAAKPKHDWT--RSYFR 320
+ + ++ + R +T L ++ +CW P + I+ P D+T +
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIV---DPFIDYTVPGQVWT 295
Query: 321 AYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
A++ L Y++S +NP LY ++ FRR F+ +LCC
Sbjct: 296 AFLWL-------GYINSGLNPFLYAFLNKSFRRAFLIILCC 329
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 79.7 bits (195), Expect = 5e-15
Identities = 76/341 (22%), Positives = 150/341 (43%), Gaps = 39/341 (11%)
Query: 30 KITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDH-MVSLACSDILVFLIGMP 88
K+ L+ + +M +LGN + V + L+K T++ +VSLA +D+LV ++ MP
Sbjct: 19 KVVLLTFLSTVILMAILGN---LLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 89 ---MEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAIC-HPFRYK 144
+E IW + C + T L + A++ H+ +S +RY AIC P Y+
Sbjct: 76 FGAIELVQDIW-----IYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130
Query: 145 AVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPET 204
P ++ L++G WV ++ + ++++ R N
Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN------------ 178
Query: 205 SNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPP 264
SN + C + ++ S+ ++ +L+++L+ + + + Q AG +
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 265 QLRKSESEESRTARRQTIIFLRLIVVT--LAVCWMPNQIRRIMAAAKPKHDWT--RSYFR 320
+ + ++ + R +T L ++ +CW P + I+ P D+T +
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIV---DPFIDYTVPGQVWT 295
Query: 321 AYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
A++ L Y++S +NP LY ++ FRR F+ +LCC
Sbjct: 296 AFLWL-------GYINSGLNPFLYAFLNKSFRRAFLIILCC 329
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 79.7 bits (195), Expect = 5e-15
Identities = 76/341 (22%), Positives = 150/341 (43%), Gaps = 39/341 (11%)
Query: 30 KITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDH-MVSLACSDILVFLIGMP 88
K+ L+ + +M +LGN + V + L+K T++ +VSLA +D+LV ++ MP
Sbjct: 19 KVVLLTFLSTVILMAILGN---LLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 89 ---MEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAIC-HPFRYK 144
+E IW + C + T L + A++ H+ +S +RY AIC P Y+
Sbjct: 76 FGAIELVQDIW-----IYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130
Query: 145 AVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPET 204
P ++ L++G WV ++ + ++++ R N
Sbjct: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN------------ 178
Query: 205 SNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPP 264
SN + C + ++ S+ ++ +L+++L+ + + + Q AG +
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 265 QLRKSESEESRTARRQTIIFLRLIVVT--LAVCWMPNQIRRIMAAAKPKHDWT--RSYFR 320
+ + ++ + R +T L ++ +CW P + I+ P D+T +
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIV---DPFIDYTVPGQVWT 295
Query: 321 AYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361
A++ L Y++S +NP LY ++ FRR F+ +LCC
Sbjct: 296 AFLWL-------GYINSGLNPFLYAFLNKSFRRAFLIILCC 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.133 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,780,286
Number of Sequences: 37866
Number of extensions: 607050
Number of successful extensions: 3802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 483
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 2415
Number of HSP's gapped (non-prelim): 1103
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.