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Search of human proteins with 4503615
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503615 even-skipped homeobox 1 [Homo sapiens]
(407 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503615 even-skipped homeobox 1 [Homo sapiens] 832 0.0
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 340 2e-93
gi|84570137 homeobox B3 [Homo sapiens] 102 8e-22
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 87 3e-17
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 86 5e-17
gi|24497589 aristaless related homeobox [Homo sapiens] 86 6e-17
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 86 8e-17
gi|4504465 homeobox B2 [Homo sapiens] 85 1e-16
gi|7110735 ventral anterior homeobox 2 [Homo sapiens] 83 5e-16
gi|24497513 homeobox A3 isoform a [Homo sapiens] 82 7e-16
gi|13562112 homeobox A3 isoform a [Homo sapiens] 82 7e-16
gi|19923391 homeobox D3 [Homo sapiens] 82 9e-16
gi|116805350 homeo box (H6 family) 1 [Homo sapiens] 79 6e-15
gi|4502365 NK3 homeobox 2 [Homo sapiens] 79 1e-14
gi|10140847 homeobox A2 [Homo sapiens] 78 1e-14
gi|24497515 homeobox A3 isoform b [Homo sapiens] 78 2e-14
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens] 77 4e-14
gi|84105335 mesenchyme homeobox 2 [Homo sapiens] 77 4e-14
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens] 77 4e-14
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens] 77 4e-14
gi|39930383 BarH-like homeobox 2 [Homo sapiens] 76 5e-14
gi|157743259 H6 family homeobox 3 [Homo sapiens] 76 6e-14
gi|14149728 BarH-like homeobox 1 [Homo sapiens] 76 6e-14
gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens] 76 6e-14
gi|24497526 homeobox B1 [Homo sapiens] 75 8e-14
gi|121114296 caudal type homeobox 1 [Homo sapiens] 75 1e-13
gi|157426823 NK2 homeobox 4 [Homo sapiens] 74 2e-13
gi|23397672 homeobox D4 [Homo sapiens] 73 4e-13
gi|89257348 homeo box HB9 [Homo sapiens] 73 4e-13
gi|23510368 homeobox D11 [Homo sapiens] 73 5e-13
>gi|4503615 even-skipped homeobox 1 [Homo sapiens]
Length = 407
Score = 832 bits (2150), Expect = 0.0
Identities = 407/407 (100%), Positives = 407/407 (100%)
Query: 1 MESRKDMVVFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRER 60
MESRKDMVVFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRER
Sbjct: 1 MESRKDMVVFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRER 60
Query: 61 GGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFY 120
GGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFY
Sbjct: 61 GGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFY 120
Query: 121 EEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSAS 180
EEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSAS
Sbjct: 121 EEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSAS 180
Query: 181 DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR
Sbjct: 181 DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
Query: 241 QRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPF 300
QRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPF
Sbjct: 241 QRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPF 300
Query: 301 SGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAGGPCSCLACHSGPANGL 360
SGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAGGPCSCLACHSGPANGL
Sbjct: 301 SGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAGGPCSCLACHSGPANGL 360
Query: 361 APRAAAASDFTCASTSRSDSFLTFAPSVLSKASSVALDQREEVPLTR 407
APRAAAASDFTCASTSRSDSFLTFAPSVLSKASSVALDQREEVPLTR
Sbjct: 361 APRAAAASDFTCASTSRSDSFLTFAPSVLSKASSVALDQREEVPLTR 407
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 340 bits (871), Expect = 2e-93
Identities = 219/483 (45%), Positives = 268/483 (55%), Gaps = 91/483 (18%)
Query: 4 RKDMVVFLDGGQLGTLVGKRVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRERGGG 63
RK+M++ ++ G GKR SNLS + G+ + E E LSPR G
Sbjct: 6 RKEMIL-MERGLHSPTAGKRFSNLSNSAGNAVLEALENSQHPARLSPRLPSAPLHSALGE 64
Query: 64 GP-----EEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESD 118
P E + + L + + +++ AA +S G S + E+D
Sbjct: 65 LPAKGKFEIDTLFNLQHTGSESTVSSEISSAA-----------ESRKKPGHYSEAAAEAD 113
Query: 119 FYEEIEVSCTPDCATGN---AEYQHSKG-----SGSEALVGSPNGGSETPKSNGGSGGGG 170
++EV C+ + G A+ + + G SGS A + GS +GGSGG G
Sbjct: 114 MSSDVEVGCSALRSPGGLGAAQLKENNGKGYAESGSAAGTTTSASGSGLGSLHGGSGGSG 173
Query: 171 SQGTLACSAS--DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIK 228
L S S DQ+RRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIK
Sbjct: 174 GSAALGGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIK 233
Query: 229 VWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLG 288
VWFQNRRMKDKRQRLAM+WPHPADP+FYTYMM+HAAA G LPYPF SH+PL YY VG+
Sbjct: 234 VWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVT 293
Query: 289 AAS-------AASAAASPFSGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLG- 340
AA+ AA+AA+SPF+ S+RPLDTFR LS PY RPELLC+FRHP LY PA G
Sbjct: 294 AAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGL 353
Query: 341 --------------------ASAG-------GPCSCLACHSGPANGLAPRAAAA------ 367
A+AG PCSCL+CHS + A AAAA
Sbjct: 354 NSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRG 413
Query: 368 ---------------------SDFTC-ASTSRSDS-FLTFAPSVLSKASSVALDQREEVP 404
SDF C A+ RS+S FL ++ +VLSK + DQR+E P
Sbjct: 414 GGGGGGGGGGGGGGGAGAGGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAP 473
Query: 405 LTR 407
LTR
Sbjct: 474 LTR 476
>gi|84570137 homeobox B3 [Homo sapiens]
Length = 431
Score = 102 bits (253), Expect = 8e-22
Identities = 73/217 (33%), Positives = 102/217 (47%), Gaps = 23/217 (10%)
Query: 29 EAVGSPLPEPPEKMVPRGCLSPRAVP-PATRERGGGGPEEEPVDGLAGSAAGPGAEPQVA 87
+++G+ P K + C+ P P P + G P P + S+ G G P +
Sbjct: 55 QSLGNAAPHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGG--PSKS 112
Query: 88 GAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSE 147
G GPG + +L+ Q P ++ + S + + G AE G G
Sbjct: 113 GPPKCGPGTNS----TLTKQIFPWMKESR-------QTSKLKNNSPGTAEGCGGGGGGGG 161
Query: 148 ALVGSPNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENY 207
G +GGS GG GGGG G + S +R RTA+T Q+ LEKEF+ Y
Sbjct: 162 ---GGGSGGS------GGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRY 212
Query: 208 VSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLA 244
+ RPRR E+A LNL E IK+WFQNRRMK K+ + A
Sbjct: 213 LCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKA 249
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 87.0 bits (214), Expect = 3e-17
Identities = 101/348 (29%), Positives = 126/348 (36%), Gaps = 81/348 (23%)
Query: 42 MVPRGCLSPRAVPPATRERGGGGP------EEEPVDGLAGSAAGPGAEPQVAGAAML--- 92
+ P C + P A G P E + G AG GAEP AG
Sbjct: 69 VAPAACAPCASAPCAPAPAASGRPPRAEELERRALAG-AGGVGAAGAEPPNAGDPFKAGE 127
Query: 93 -----------GPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHS 141
G G +PS DS G P D + D E E + + A G +
Sbjct: 128 AETNDTNGYSSGGGGHSPSADS--GDEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGA 185
Query: 142 KGSGSEALV-------------GSPNGGSETPKSNGGSGG----GGS----QGTLAC--- 177
+GSG + +P +P + G GG GG+ QGT
Sbjct: 186 RGSGCQGAAETDASPGATVDEAAAPGPRENSPVAQGPPGGAAAPGGAGTTPQGTATAAKP 245
Query: 178 --------SASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKV 229
S S + RR RTAFT EQ+ LE +F Y+S R LA +L+L ET +K+
Sbjct: 246 KRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKI 305
Query: 230 WFQNRRMKDKRQRLAMTWPHP----------ADPAFYTYMMSHAAAAGGL----PYPFPS 275
WFQNRR K K+Q P A P GGL P P P
Sbjct: 306 WFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPG--------TGLPGGLSPLSPSP-PM 356
Query: 276 HLPLPYYSPVGL---GAASAASAAASPFSGSLRPLDTFRVLSQPYPRP 320
PL + P G G AA PF S L F + SQ Y P
Sbjct: 357 GAPLGMHGPAGYPAHGPGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAP 404
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 86.3 bits (212), Expect = 5e-17
Identities = 101/348 (29%), Positives = 126/348 (36%), Gaps = 81/348 (23%)
Query: 42 MVPRGCLSPRAVPPATRERGGGGP------EEEPVDGLAGSAAGPGAEPQVAGAAML--- 92
+ P C + P A G P E + G AG GAEP AG
Sbjct: 472 VAPAACAPCASAPCAPAPAASGRPPRAEELERRALAG-AGGVGAAGAEPPNAGDPFKAGE 530
Query: 93 -----------GPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHS 141
G G +PS DS G P D + D E E + + A G +
Sbjct: 531 AETNDTNGYSSGGGGHSPSADS--GDEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGA 588
Query: 142 KGSGSEALV-------------GSPNGGSETPKSNGGSGG----GGS----QGTLAC--- 177
+GSG + +P +P + G GG GG+ QGT
Sbjct: 589 RGSGCQGAAETDASPGATVDEAAAPGPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKP 648
Query: 178 --------SASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKV 229
S S + RR RTAFT EQ+ LE +F Y+S R LA +L+L ET +K+
Sbjct: 649 KRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKI 708
Query: 230 WFQNRRMKDKRQRLAMTWPHP----------ADPAFYTYMMSHAAAAGGL----PYPFPS 275
WFQNRR K K+Q P A P GGL P P P
Sbjct: 709 WFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPG--------TGLPGGLSPLSPSP-PM 759
Query: 276 HLPLPYYSPVGL---GAASAASAAASPFSGSLRPLDTFRVLSQPYPRP 320
PL + P G G AA PF S L F + SQ Y P
Sbjct: 760 GAPLGMHGPAGYPAHGPGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAP 807
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 85.9 bits (211), Expect = 6e-17
Identities = 109/395 (27%), Positives = 149/395 (37%), Gaps = 67/395 (16%)
Query: 54 PPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSS 113
PPA E GG G P + L G A GPG+ P G G G + L +
Sbjct: 186 PPALDELGGPGGVTHPEERL-GVAGGPGSAPAAGG----GTGTEDDEEELLEDE---EDE 237
Query: 114 DTESDFYEEIEVSCTPDCATGNAEYQH-------SKGSGSEALVGSPNGGSETPKSN--- 163
D E + E+ E D A + + + A + GG +PK
Sbjct: 238 DEEEELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLL 297
Query: 164 ---GGSGGGGSQGTLACSASD--------QMRRYRTAFTREQIARLEKEFYRENYVSRPR 212
G G + SD + RRYRT FT Q+ LE+ F + +Y
Sbjct: 298 HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
Query: 213 RCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHP-----ADPAFYTYMMSHAAAAG 267
R ELA L+L E ++VWFQNRR K +++ A HP P T+ +S A
Sbjct: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDAS 417
Query: 268 GLPYPFPSHLPLPYYSPVGLGAASAAS---------AAASPFSGSLRPLDTFRVLSQPYP 318
PFP H P + AA+AA+ +A+ P SG+ L TF +
Sbjct: 418 ----PFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAA---- 469
Query: 319 RPELLCAFRHPPLYPGPAHGLGASAGGP------CSCLACHSGPA-NGLAPRAAAASDFT 371
FRH P + PA G S P + L PA G A A T
Sbjct: 470 ------VFRH-PAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPAT 522
Query: 372 CASTSRSDSFLTFAPSVLSKASSVALDQREEVPLT 406
A+ R+ S A + +K + L Q +P T
Sbjct: 523 AAADRRASSIA--ALRLKAKEHAAQLTQLNILPGT 555
Score = 34.3 bits (77), Expect = 0.21
Identities = 41/170 (24%), Positives = 57/170 (33%), Gaps = 15/170 (8%)
Query: 52 AVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPS 111
A AT G P P A PG P AGAA A + D+L P
Sbjct: 113 AAATATAGPRGEAPPPPP------PTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQ 166
Query: 112 SSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGS 171
S + S Y E P + + E +G G P + GG+G
Sbjct: 167 VSISRSKSYRENGAPFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDD 226
Query: 172 QGTLACSASDQMRRYRTAFTREQIARLEKEFYREN---YVSRPRRCELAA 218
+ L D+ E + E+E ++ + PRRC +AA
Sbjct: 227 EEELLEDEEDEDEE------EELLEDDEEELLEDDARALLKEPRRCPVAA 270
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 85.5 bits (210), Expect = 8e-17
Identities = 67/215 (31%), Positives = 89/215 (41%), Gaps = 17/215 (7%)
Query: 37 EPPEKMV-PRGCLSPRAVPPATRERGGGGPE-EEPVDGLAGSAAGPGAEPQVAGAAMLGP 94
EPP+ P+ + A AT R P P GL P E + P
Sbjct: 110 EPPDAFYGPQELAAAAAAAAATAARNNPEPGGRRPEGGLEADELLPAREK------VAEP 163
Query: 95 GPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPN 154
PP P S + P+ S E++E S + E S + + S
Sbjct: 164 PPPPPPHFSETFPSLPAEGKVYSSDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSA 223
Query: 155 GG-----SETPKSNGGSGGGGSQGTLACSA----SDQMRRYRTAFTREQIARLEKEFYRE 205
GG PK G G G +G + + RR RTAFT EQ+ LEKEF+ +
Sbjct: 224 GGPGALLGPKPKLKGSLGTGAEEGAPVTAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCK 283
Query: 206 NYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
Y+S R ++A AL L E +K+WFQNRR K KR
Sbjct: 284 KYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 318
>gi|4504465 homeobox B2 [Homo sapiens]
Length = 356
Score = 85.1 bits (209), Expect = 1e-16
Identities = 75/222 (33%), Positives = 97/222 (43%), Gaps = 56/222 (25%)
Query: 23 RVSNLSEAVGSPLPEPPEKMVPRGCLSPRAVP---PATRERGGGGPEEEPVDGLAGSAAG 79
+ S++ E+ P P P E+ P L P A P +++R GP A
Sbjct: 33 QTSSIKESTLIPPPPPFEQTFPS--LQPGASTLQRPRSQKRAEDGP-----------ALP 79
Query: 80 PGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQ 139
P P + A P P P + +PS S T S P A+G
Sbjct: 80 PPPPPPLPAAP---PAPEFPWMKEKKSAKKPSQSATSPS----PAASAVP--ASG----- 125
Query: 140 HSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLE 199
VGSP G P++ GGGG+ RR RTA+T Q+ LE
Sbjct: 126 ----------VGSPADGLGLPEA----GGGGA------------RRLRTAYTNTQLLELE 159
Query: 200 KEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQ 241
KEF+ Y+ RPRR E+AA L+L E +KVWFQNRRMK KRQ
Sbjct: 160 KEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 201
>gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
Length = 290
Score = 82.8 bits (203), Expect = 5e-16
Identities = 74/186 (39%), Positives = 90/186 (48%), Gaps = 10/186 (5%)
Query: 181 DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
D+ +R RT+FT EQ+ RLE EF R YV R ELA LNL ET +KVWFQNRR K K+
Sbjct: 100 DRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 159
Query: 241 QR---LAMTWPHPADPAFYTYMMSHAAAAGG-LPYP-FPSHLPLPYYSPVGLGAASAASA 295
+ L A AF T + G L P PS L L P GL A+ ++
Sbjct: 160 DQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLP-GLPASHRGTS 218
Query: 296 AASPFSGS--LRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPA-HGLGASAGGPCSCLAC 352
P + S L PL + S P P P F PL PA + LG+SA P S L
Sbjct: 219 LGDPRNSSPRLNPLSSASA-SPPLPPPLPAVCFSSAPLLDLPAGYELGSSAFEPYSWLER 277
Query: 353 HSGPAN 358
G A+
Sbjct: 278 KVGSAS 283
>gi|24497513 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 82.4 bits (202), Expect = 7e-16
Identities = 89/332 (26%), Positives = 121/332 (36%), Gaps = 50/332 (15%)
Query: 38 PPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPP 97
P + CL + PP+ G P P AA P +P P P
Sbjct: 62 PKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPP----QAAPPAPQPPQPAPQPPAPTPA 117
Query: 98 APSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATG-----NAEYQHSKGSGSEALVGS 152
AP S + Q +S++ + + +P A Q++K S + G
Sbjct: 118 APPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGE 177
Query: 153 PNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPR 212
G ++P S +R RTA+T Q+ LEKEF+ Y+ RPR
Sbjct: 178 SCAGDKSPPGQASS-----------------KRARTAYTSAQLVELEKEFHFNRYLCRPR 220
Query: 213 RCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYP 272
R E+A LNL E IK+WFQNRRMK K+ + ++GG
Sbjct: 221 RVEMANLLNLTERQIKIWFQNRRMKYKKDQKG---------------KGMLTSSGG---Q 262
Query: 273 FPSHLPLP-----YYSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPELLCAFR 327
PS P+P Y + + S SP S P T+ + YP CA
Sbjct: 263 SPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPP 322
Query: 328 HPPLYPGPAHGLGASAGGPCSCLACHSGPANG 359
PP A G GA G P H NG
Sbjct: 323 PPPQKRYTAAGAGA-GGTPDYDPHAHGLQGNG 353
>gi|13562112 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 82.4 bits (202), Expect = 7e-16
Identities = 89/332 (26%), Positives = 121/332 (36%), Gaps = 50/332 (15%)
Query: 38 PPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPP 97
P + CL + PP+ G P P AA P +P P P
Sbjct: 62 PKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPP----QAAPPAPQPPQPAPQPPAPTPA 117
Query: 98 APSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATG-----NAEYQHSKGSGSEALVGS 152
AP S + Q +S++ + + +P A Q++K S + G
Sbjct: 118 APPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGE 177
Query: 153 PNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPR 212
G ++P S +R RTA+T Q+ LEKEF+ Y+ RPR
Sbjct: 178 SCAGDKSPPGQASS-----------------KRARTAYTSAQLVELEKEFHFNRYLCRPR 220
Query: 213 RCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYP 272
R E+A LNL E IK+WFQNRRMK K+ + ++GG
Sbjct: 221 RVEMANLLNLTERQIKIWFQNRRMKYKKDQKG---------------KGMLTSSGG---Q 262
Query: 273 FPSHLPLP-----YYSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPELLCAFR 327
PS P+P Y + + S SP S P T+ + YP CA
Sbjct: 263 SPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPP 322
Query: 328 HPPLYPGPAHGLGASAGGPCSCLACHSGPANG 359
PP A G GA G P H NG
Sbjct: 323 PPPQKRYTAAGAGA-GGTPDYDPHAHGLQGNG 353
>gi|19923391 homeobox D3 [Homo sapiens]
Length = 432
Score = 82.0 bits (201), Expect = 9e-16
Identities = 95/339 (28%), Positives = 133/339 (39%), Gaps = 56/339 (16%)
Query: 54 PPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSS 113
P +GGGG + P GL P P P P V + +G P++S
Sbjct: 93 PGTGNSQGGGGGSQPP--GLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNAS 150
Query: 114 DTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQG 173
+ + ++I Q+SK S A G S KS G
Sbjct: 151 SSSATISKQI-------FPWMKESRQNSKQKNSCATAGE----SCEDKSPPGPAS----- 194
Query: 174 TLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQN 233
+R RTA+T Q+ LEKEF+ Y+ RPRR E+A LNL E IK+WFQN
Sbjct: 195 ----------KRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 244
Query: 234 RRMKDKRQRLAMTWPHPADPAFYTYMMS--------HAAAAGGLPYPFPSHLPLPYYSPV 285
RRMK K+ + A H PA + S H A +G LP P P L Y +P
Sbjct: 245 RRMKYKKDQKAKGILH--SPASQSPERSPPLGGAAGHVAYSGQLP-PVPG---LAYDAPS 298
Query: 286 GLGAASA------ASAAASPFSGSLRPLDTFRVLS-QPYPRPELLCAFRHPPLYPGPAHG 338
A + +A +P S L + +P+P F L P +
Sbjct: 299 PPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVY- 357
Query: 339 LGASAGGPCSCLACHSGPA---NGLAPRAAAASDFTCAS 374
G +A SGP L+ ++A+ D++CA+
Sbjct: 358 ---VGGNFVESMAPASGPVFNLGHLSHPSSASVDYSCAA 393
>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
Length = 348
Score = 79.3 bits (194), Expect = 6e-15
Identities = 87/285 (30%), Positives = 112/285 (39%), Gaps = 72/285 (25%)
Query: 73 LAGSAAGPGAEPQVAGAAMLGPG--------PPAPSVDSLSGQG---------------- 108
LAG+ GPG E + A+LGPG PP P G G
Sbjct: 72 LAGT--GPGGEARAR--ALLGPGALGLGPRPPPGPGPPFALGCGGAARWYPRAHGGYGGG 127
Query: 109 -QPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSG--------SEALVGSPNGGSE- 158
P +SD +S E G AE +G G +E P G+E
Sbjct: 128 LSPDTSDRDSPETGE---------EMGRAEGAWPRGPGPGAVQREAAELAARGPAAGTEE 178
Query: 159 ------TPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPR 212
P + G + GG G + ++ RT F+R Q+ +LE F + Y+S
Sbjct: 179 ASELAEVPAAAGETRGGVGVG------GGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAE 232
Query: 213 RCELAAALNLPETTIKVWFQNRRMKDKRQ-----RLAMTWPHPAD-----PAFYTYMMSH 262
R LAA+L L ET +K+WFQNRR K KRQ A P A P Y
Sbjct: 233 RAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQRLVRVPVLYHESPPA 292
Query: 263 AAAAG---GLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGSL 304
AAAAG LP+P P P +G A A AA P + S+
Sbjct: 293 AAAAGPPATLPFPLAPAAPAPPPPLLGFSGALAYPLAAFPAAASV 337
>gi|4502365 NK3 homeobox 2 [Homo sapiens]
Length = 333
Score = 78.6 bits (192), Expect = 1e-14
Identities = 86/322 (26%), Positives = 128/322 (39%), Gaps = 74/322 (22%)
Query: 49 SPRAVPPATRERGG-GGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGP---GPPAPSVDSL 104
S +A+ ERGG PE P G G+AA A P V + G G + DSL
Sbjct: 13 SIQAILNKKEERGGLAAPEGRPAPG--GTAASVAAAPAVCCWRLFGERDAGALGGAEDSL 70
Query: 105 SGQG------------QPSSSDTESDFYEEIEVS--CT-------------------PDC 131
P D++S EE E C P C
Sbjct: 71 LASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAGGSLSLGQPVC 130
Query: 132 ATGNAEYQHSKGSG-SEALVGSPNGGSETPKSN---------------GGSGGGGSQGTL 175
++ + +G S++ + + G +P++ G+GGGG G
Sbjct: 131 ELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALCSGAGGGGGSGPA 190
Query: 176 ACSASDQ--------MRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTI 227
+ ++ +R R AF+ Q+ LE+ F + Y+S P R +LAA+L L ET +
Sbjct: 191 GVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQV 250
Query: 228 KVWFQNRRMKDKRQRLA--MTWPHPADPAFYTYMMSHAAAAGGLPYPF---PSHLPL--- 279
K+WFQNRR K KR+++A + PA ++ LP PS LPL
Sbjct: 251 KIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPS 310
Query: 280 ---PYYSPVGLGAASAASAAAS 298
PYY G ++ A+AA +
Sbjct: 311 YYYPYYCLPGWALSTCAAAAGT 332
>gi|10140847 homeobox A2 [Homo sapiens]
Length = 376
Score = 78.2 bits (191), Expect = 1e-14
Identities = 41/77 (53%), Positives = 48/77 (62%), Gaps = 13/77 (16%)
Query: 165 GSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPE 224
GSGGG RR RTA+T Q+ LEKEF+ Y+ RPRR E+AA L+L E
Sbjct: 138 GSGGGS-------------RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTE 184
Query: 225 TTIKVWFQNRRMKDKRQ 241
+KVWFQNRRMK KRQ
Sbjct: 185 RQVKVWFQNRRMKHKRQ 201
>gi|24497515 homeobox A3 isoform b [Homo sapiens]
Length = 285
Score = 77.8 bits (190), Expect = 2e-14
Identities = 65/204 (31%), Positives = 84/204 (41%), Gaps = 24/204 (11%)
Query: 161 KSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAAL 220
K++ S G G + +R RTA+T Q+ LEKEF+ Y+ RPRR E+A L
Sbjct: 11 KTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLL 70
Query: 221 NLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLP 280
NL E IK+WFQNRRMK K+ + ++GG PS P+P
Sbjct: 71 NLTERQIKIWFQNRRMKYKKDQKG---------------KGMLTSSGG---QSPSRSPVP 112
Query: 281 -----YYSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGP 335
Y + + S SP S P T+ + YP CA PP
Sbjct: 113 PGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYT 172
Query: 336 AHGLGASAGGPCSCLACHSGPANG 359
A G GA G P H NG
Sbjct: 173 AAGAGA-GGTPDYDPHAHGLQGNG 195
>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
Length = 283
Score = 76.6 bits (187), Expect = 4e-14
Identities = 36/61 (59%), Positives = 45/61 (73%)
Query: 181 DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
++ +R RTA+TR Q+ LEKEF Y+SRPRR ELA LNL E IK+WFQNRRMK K+
Sbjct: 144 EENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKK 203
Query: 241 Q 241
+
Sbjct: 204 E 204
>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
Length = 304
Score = 76.6 bits (187), Expect = 4e-14
Identities = 59/163 (36%), Positives = 77/163 (47%), Gaps = 34/163 (20%)
Query: 83 EPQVAGAAMLGPGPPAPSVDSLS-GQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHS 141
+P G LG PP +S S G P+ + CA G+
Sbjct: 111 QPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAA----------------CAPGDY----- 149
Query: 142 KGSGSEALVGSPNGGSETPKSNGGSGGGGS----QGTLACSASDQMRRYRTAFTREQIAR 197
G +AL SP +E K +GG S +G + + R+ RTAFT+EQI
Sbjct: 150 ---GRQAL--SP---AEAEKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRE 201
Query: 198 LEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
LE EF NY++R RR E+A L+L E +KVWFQNRRMK KR
Sbjct: 202 LEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKR 244
>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 653
Score = 76.6 bits (187), Expect = 4e-14
Identities = 63/186 (33%), Positives = 79/186 (42%), Gaps = 26/186 (13%)
Query: 152 SPNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRP 211
+P G TP+ + + T + S S + RR RTAFT EQ+ LE +F Y+S
Sbjct: 66 APGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVC 125
Query: 212 RRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHP----------ADPAFYTYMMS 261
R LA +L+L ET +K+WFQNRR K K+Q P A P
Sbjct: 126 ERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPG------- 178
Query: 262 HAAAAGGL----PYPFPSHLPLPYYSPVGL---GAASAASAAASPFSGSLRPLDTFRVLS 314
GGL P P P PL + P G G AA PF S L F + S
Sbjct: 179 -TGLPGGLSPLSPSP-PMGAPLGMHGPAGYPAHGPGGLVCAAQLPFLSSPAVLSPFVLGS 236
Query: 315 QPYPRP 320
Q Y P
Sbjct: 237 QTYGAP 242
Score = 31.6 bits (70), Expect = 1.3
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 1/63 (1%)
Query: 54 PPATRERGGGGPEEEPV-DGLAGSAAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQGQPSS 112
PP+TR+R G E PV G G AA PG P S S G+P
Sbjct: 40 PPSTRQRPPGPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRR 99
Query: 113 SDT 115
+ T
Sbjct: 100 ART 102
>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
Length = 348
Score = 76.6 bits (187), Expect = 4e-14
Identities = 57/150 (38%), Positives = 74/150 (49%), Gaps = 24/150 (16%)
Query: 98 APSVDSLSGQGQPSSS------DTESDFYEEIEVS-CTPDCATGNAEYQHSKGSGSEALV 150
A V ++ GQG+ S E F E +V + D TG A H + AL
Sbjct: 172 ASLVGAVRGQGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAA--HKEEDPGHAL- 228
Query: 151 GSPNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSR 210
ETP S+G +G S G + RR RTAFT EQ+ LEKEF+ + Y+S
Sbjct: 229 ------EETPPSSGAAGSTTSTG--------KNRRRRTAFTSEQLLELEKEFHCKKYLSL 274
Query: 211 PRRCELAAALNLPETTIKVWFQNRRMKDKR 240
R ++A AL L E +K+WFQNRR K KR
Sbjct: 275 TERSQIAHALKLSEVQVKIWFQNRRAKWKR 304
>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
Length = 387
Score = 76.3 bits (186), Expect = 5e-14
Identities = 61/162 (37%), Positives = 82/162 (50%), Gaps = 33/162 (20%)
Query: 184 RRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRL 243
R+ RTAF+ Q+ +LE+ F R+ Y+S R +LAAALNL +T +K W+QNRR K KRQ
Sbjct: 233 RKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQ-- 290
Query: 244 AMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPY-YSPVGLG---AASAASAAASP 299
A +++ A L FPS PY Y P LG + +AA+AAA+
Sbjct: 291 ---------TAVGLELLAEAGNYSALQRMFPS----PYFYHPSLLGSMDSTTAAAAAAAM 337
Query: 300 FSGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGP-AHGLG 340
+S R + P P P+L PL P HGLG
Sbjct: 338 YSSMYR--------TPPAPHPQL-----QRPLVPRVLIHGLG 366
>gi|157743259 H6 family homeobox 3 [Homo sapiens]
Length = 357
Score = 75.9 bits (185), Expect = 6e-14
Identities = 72/240 (30%), Positives = 107/240 (44%), Gaps = 33/240 (13%)
Query: 77 AAGPGAEPQVAGAAMLGPGPPAPSVDSLSGQ----GQPSSSDTESDFYEEIEVSCTPDCA 132
A G P+ + A+L PA D S + P + +S +EI +
Sbjct: 125 AGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILE------ 178
Query: 133 TGNAEYQHSKGSGSEALVGSPNGGSE-TPKSNGGSGGGGS-QGTLACSASDQMRRYRTAF 190
++E +G + G+ G + TP + G S + AC + ++ RT F
Sbjct: 179 ESDSEESKKEGEAAPGAAGASVGAAAATPGAEDWKKGAESPEKKPAC----RKKKTRTVF 234
Query: 191 TREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHP 250
+R Q+ +LE F + Y+S R LAA+L+L ET +K+WFQNRR K KRQ A
Sbjct: 235 SRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAA------ 288
Query: 251 ADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGSLRPLDTF 310
+SHAAA + P L + + GAA+AA+ A P S +PL TF
Sbjct: 289 ---ELEAANLSHAAAQRIVRVPI-----LYHENSAAEGAAAAAAGAPVPVS---QPLLTF 337
>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
Length = 327
Score = 75.9 bits (185), Expect = 6e-14
Identities = 85/304 (27%), Positives = 122/304 (40%), Gaps = 50/304 (16%)
Query: 25 SNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEP 84
S LS GSP + ++ C SP + P + S A PG +
Sbjct: 11 SILSHRAGSPALPKGDPLLG-DCRSPLELSPRSESSSD-----------CSSPASPGRDC 58
Query: 85 QVAGAAMLGPGPPAPSVDSLSGQGQPSS-----SDTESDFYEEIEVSCTP--DCATGNAE 137
G G G P +DS GQ S+ + T S +I C P CA ++
Sbjct: 59 LETGTPRPG-GASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSS 117
Query: 138 YQHS--KGSGSEALVGSPNGGSETPKSNGGSGGGGS-----QGTLACSAS--------DQ 182
Q + + G A + + + KS + +G S+S +
Sbjct: 118 GQPAAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKK 177
Query: 183 MRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQR 242
R+ RTAFT Q+A+LE+ F R+ Y+S R ELAA+LNL +T +K W+QNRR K KRQ
Sbjct: 178 PRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQ- 236
Query: 243 LAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSG 302
A +++ A L FPS PY+ P L + AA + G
Sbjct: 237 ----------TAVGLELLAEAGNYSALQRMFPS----PYFYPQSLVSNLDPGAALYLYRG 282
Query: 303 SLRP 306
P
Sbjct: 283 PSAP 286
>gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens]
Length = 334
Score = 75.9 bits (185), Expect = 6e-14
Identities = 65/186 (34%), Positives = 77/186 (41%), Gaps = 37/186 (19%)
Query: 181 DQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
D+ +R RT+FT EQ+ RLE EF R YV R ELA LNL ET +KVWFQNRR K K+
Sbjct: 98 DRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 157
Query: 241 QRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPF 300
+ D + + AA L L SP GL A
Sbjct: 158 DQ-------GKDSELRSVVSETAATCSVLRLLEQGRL----LSPPGLPA----------- 195
Query: 301 SGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAGGPCSCLACHSGPANGL 360
L P L A R P L PA G GA+AG + A GPA
Sbjct: 196 ------------LLPPCATGALGSALRGPSL---PALGAGAAAGSAAAAAAAAPGPAGAA 240
Query: 361 APRAAA 366
+P A
Sbjct: 241 SPHPPA 246
>gi|24497526 homeobox B1 [Homo sapiens]
Length = 301
Score = 75.5 bits (184), Expect = 8e-14
Identities = 68/237 (28%), Positives = 89/237 (37%), Gaps = 40/237 (16%)
Query: 32 GSPLPEPPEKM-VPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSA---------AGPG 81
G P +PP + VP +P PA G + P+ G A G
Sbjct: 62 GYPAQQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSYGAQLG 121
Query: 82 AEPQVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFY-EEIEVSCTPDCATGNAE--- 137
GA GPGP P + S + +D E+ E C + T A
Sbjct: 122 GLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTFD 181
Query: 138 -YQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIA 196
+ + A V P GS + RT FT Q+
Sbjct: 182 WMKVKRNPPKTAKVSEPGLGSPSG-------------------------LRTNFTTRQLT 216
Query: 197 RLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADP 253
LEKEF+ Y+SR RR E+AA L L ET +K+WFQNRRMK K++ PA P
Sbjct: 217 ELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREEGRVPPAPP 273
>gi|121114296 caudal type homeobox 1 [Homo sapiens]
Length = 265
Score = 75.1 bits (183), Expect = 1e-13
Identities = 66/226 (29%), Positives = 81/226 (35%), Gaps = 56/226 (24%)
Query: 29 EAVGSPLPEPPEKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAG 88
+A G P P P P P G P P D A +A GPG A
Sbjct: 28 QAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWA-AAYGPGPAAPAAS 86
Query: 89 AAMLGPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEA 148
A L GPP DF V P G
Sbjct: 87 PASLAFGPPP-------------------DFSP---VPAPPGPGPG-------------- 110
Query: 149 LVGSPNGGSETPKSNGG--------------SGGGGSQGTLACSASDQMRRYRTAFTREQ 194
L+ P GG TP S G +GGGG G +YR +T Q
Sbjct: 111 LLAQPLGGPGTPSSPGAQRPTPYEWMRRSVAAGGGGGSGKTRTKD-----KYRVVYTDHQ 165
Query: 195 IARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
LEKEF+ Y++ R+ ELAA L L E +K+WFQNRR K+++
Sbjct: 166 RLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERK 211
>gi|157426823 NK2 homeobox 4 [Homo sapiens]
Length = 354
Score = 73.9 bits (180), Expect = 2e-13
Identities = 86/317 (27%), Positives = 115/317 (36%), Gaps = 33/317 (10%)
Query: 38 PPEKMVPRGCLSP-RAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGP 96
PP P G + RA PP + +P +AG A A A AA
Sbjct: 35 PPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYH 94
Query: 97 PAPSVDSLSGQGQPSSSDTESDFYEEIEV---SCTPDCATG----NAEYQHSKGS---GS 146
P V S + E+ ATG N + ++S S G
Sbjct: 95 MPPGVSQFPHGAMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGANPDPRYSSISRFMGP 154
Query: 147 EALVGSPNGGSETPKSNGGSGGGGSQGTL--ACSASDQMRRYRTAFTREQIARLEKEFYR 204
A V GS T G + S G L A +A+ R+ R F++ Q+ LE+ F +
Sbjct: 155 SAGVNVAGMGSLT----GIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELERRFKQ 210
Query: 205 ENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAA 264
+ Y+S P R LA+ ++L T +K+WFQN R K KRQ D A
Sbjct: 211 QKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ--------AKDKAAQQLQQEGGL 262
Query: 265 AAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPELLC 324
P P P + +P G + AS +G P P P PEL
Sbjct: 263 GPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPP--------APTPAPELEE 314
Query: 325 AFRHPPLYPGPAHGLGA 341
PP GP GL A
Sbjct: 315 LSPSPPALHGPGGGLAA 331
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 73.2 bits (178), Expect = 4e-13
Identities = 63/185 (34%), Positives = 77/185 (41%), Gaps = 41/185 (22%)
Query: 61 GGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPG-----PPAPSVDSLSGQGQPSSSDT 115
GG GP G A A G G EP G PG PPAP L G S SD
Sbjct: 63 GGSGPGP----GSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDP 118
Query: 116 ESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTL 175
+ P T + + V S N P GG
Sbjct: 119 KQ-----------PPSGTALKQPAVVYPWMKKVHVNSVN-----PNYTGG---------- 152
Query: 176 ACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRR 235
+ +R RTA+TR+Q+ LEKEF+ Y++R RR E+A L L E IK+WFQNRR
Sbjct: 153 ------EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRR 206
Query: 236 MKDKR 240
MK K+
Sbjct: 207 MKWKK 211
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 73.2 bits (178), Expect = 4e-13
Identities = 75/265 (28%), Positives = 99/265 (37%), Gaps = 43/265 (16%)
Query: 13 GGQLGTLVGKRVSNLSEAVGSPL-------PEPPEKMVPRGCLSPRAVPPATRERGGG-- 63
GG G G SE +P P PP + L P+ GGG
Sbjct: 48 GGASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTG 107
Query: 64 ----GPEEEPVDGLAGSAAGPGAEPQVAGAAM-LGPGPPAPSVDSLSGQGQPSSSDTESD 118
GP G A +AA A G A+ L PG + G G P+ ++
Sbjct: 108 GGHGGPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPG------GAQGGAGLPA----QAA 157
Query: 119 FYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACS 178
Y + A QH S S V + G+G L S
Sbjct: 158 LYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRAS 217
Query: 179 ASDQM-------------------RRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAA 219
+ + RR RTAFT +Q+ LE +F Y+SRP+R E+A +
Sbjct: 218 TAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATS 277
Query: 220 LNLPETTIKVWFQNRRMKDKRQRLA 244
L L ET +K+WFQNRRMK KR + A
Sbjct: 278 LMLTETQVKIWFQNRRMKWKRSKKA 302
Score = 35.0 bits (79), Expect = 0.12
Identities = 35/106 (33%), Positives = 43/106 (40%), Gaps = 14/106 (13%)
Query: 286 GLGAASAASAAASPFSGS--LRPLDTFRVLSQPYPRPELL---CAFRHPPLYPGPAHGLG 340
G GA+ S + SP S P D R S P P P LL CA P + G G G
Sbjct: 47 GGGASGGTSGSCSPASSEPPAAPADRLRAES-PSP-PRLLAAHCALLPKPGFLGAGGGGG 104
Query: 341 ASAGGPCSCLACHSGPANGLAPRAAAASDFTCASTSRSDSFLTFAP 386
+ GG H GP + P AAAA+ A+ + L P
Sbjct: 105 GTGGG-------HGGPHHHAHPGAAAAAAAAAAAAAAGGLALGLHP 143
>gi|23510368 homeobox D11 [Homo sapiens]
Length = 338
Score = 72.8 bits (177), Expect = 5e-13
Identities = 62/218 (28%), Positives = 88/218 (40%), Gaps = 54/218 (24%)
Query: 53 VPPATRERGGGGPEEEPVDGLAGSAAGP--------------GAEPQ--------VAGAA 90
+PPA R EPV G GP G PQ G
Sbjct: 130 LPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPP 189
Query: 91 MLGPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALV 150
GP PP P QP + + D P G G GS
Sbjct: 190 FAGPQPPPPPAPP-----QPEGAADKGD----------PRTGAGG-------GGGSPCTK 227
Query: 151 GSPNGGSETPKSNGGSGG--------GGSQGTLACSASDQMRRYRTAFTREQIARLEKEF 202
+P GSE + GSGG G++ + + A + R+ R +T+ QI LE+EF
Sbjct: 228 ATP--GSEPKGAAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIRELEREF 285
Query: 203 YRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240
+ Y+++ +R +L+ LNL + +K+WFQNRRMK+K+
Sbjct: 286 FFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 323
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,741,060
Number of Sequences: 37866
Number of extensions: 1336034
Number of successful extensions: 9897
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 333
Number of HSP's successfully gapped in prelim test: 585
Number of HSP's that attempted gapping in prelim test: 7320
Number of HSP's gapped (non-prelim): 2731
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.