Search of human proteins with 4503281

Search of human proteins with 4503281

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503281 dopa decarboxylase (aromatic L-amino acid
decarboxylase) [Homo sapiens]
         (480 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|132814448 dopa decarboxylase (aromatic L-amino acid decarboxy...   978   0.0  
gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxyla...   978   0.0  
gi|92110055 histidine decarboxylase [Homo sapiens]                    536   e-152
gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]    139   4e-33
gi|197276620 glutamate decarboxylase 2 [Homo sapiens]                 139   7e-33
gi|4503875 glutamate decarboxylase 2 [Homo sapiens]                   139   7e-33
gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]            132   9e-31
gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]      118   1e-26
gi|190341074 pyridoxal-dependent decarboxylase domain containing...    45   1e-04
gi|5174593 melatonin receptor 1A [Homo sapiens]                        32   0.98 
gi|119703755 laminin, beta 2 precursor [Homo sapiens]                  32   1.3  
gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]             30   4.9  
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]                30   4.9  
gi|10190742 ubiquitin specific peptidase 29 [Homo sapiens]             29   8.3  

>gi|132814448 dopa decarboxylase (aromatic L-amino acid
           decarboxylase) [Homo sapiens]
          Length = 480

 Score =  978 bits (2528), Expect = 0.0
 Identities = 480/480 (100%), Positives = 480/480 (100%)

Query: 1   MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60
           MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
Sbjct: 1   MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60

Query: 61  EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120
           EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
Sbjct: 61  EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120

Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180
           WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
Sbjct: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180

Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240
           EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
Sbjct: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240

Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300
           ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
Sbjct: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300

Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360
           PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
Sbjct: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360

Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420
           KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
Sbjct: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420

Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE 480
           EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
Sbjct: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE 480


>gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxylase)
           [Homo sapiens]
          Length = 480

 Score =  978 bits (2528), Expect = 0.0
 Identities = 480/480 (100%), Positives = 480/480 (100%)

Query: 1   MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60
           MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
Sbjct: 1   MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60

Query: 61  EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120
           EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
Sbjct: 61  EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120

Query: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180
           WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
Sbjct: 121 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM 180

Query: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240
           EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
Sbjct: 181 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV 240

Query: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300
           ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
Sbjct: 241 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN 300

Query: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360
           PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
Sbjct: 301 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL 360

Query: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420
           KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
Sbjct: 361 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN 420

Query: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE 480
           EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
Sbjct: 421 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE 480


>gi|92110055 histidine decarboxylase [Homo sapiens]
          Length = 662

 Score =  536 bits (1380), Expect = e-152
 Identities = 248/476 (52%), Positives = 346/476 (72%), Gaps = 3/476 (0%)

Query: 1   MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV 60
           M   E+R RG+EMVDY+  Y+  +  R+V PDV+PGYLR  +P +AP++PD+++ I  D+
Sbjct: 2   MEPEEYRERGREMVDYICQYLSTVRERRVTPDVQPGYLRAQLPESAPEDPDSWDSIFGDI 61

Query: 61  EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD 120
           E+IIMPGV HW SP+  AY+P  +S+P++L DML  AI C+GF+WA+SPACTELE  +MD
Sbjct: 62  ERIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVMD 121

Query: 121 WLGKMLELPKAFLNEK-AGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAI 179
           WL KML LP+ FL+   + +GGGV+Q + SE+TL+ALLAAR   I  ++ + P+  ++ +
Sbjct: 122 WLAKMLGLPEHFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDADESCL 181

Query: 180 MEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFM 239
             +LVAY+SDQAHSSVE+AGLI  VK+K +P D NF++R  ALQ+A+E DK  GL+P F+
Sbjct: 182 NARLVAYASDQAHSSVEKAGLISLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVFV 241

Query: 240 VATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNF 299
            ATLGTT  C+FD L E+GPIC +E +WLH+DAAYAG+AF+CPEFR  L G+E+ADSF F
Sbjct: 242 CATLGTTGVCAFDCLSELGPICAREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFTF 301

Query: 300 NPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRS 359
           NP KW++V+FDC+  WVK +  L   F ++P YL+H+  +SG+ TD+ HWQIPL RRFRS
Sbjct: 302 NPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHA--NSGVATDFMHWQIPLSRRFRS 359

Query: 360 LKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKV 419
           +K+WFV R +GVK LQA++R   +++  FESLVR DP FEI  +  LGLV FRLKG N +
Sbjct: 360 VKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRNDPSFEIPAKRHLGLVVFRLKGPNCL 419

Query: 420 NEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVL 475
            E +L+ I  A ++ L+P  ++DK ++RF + S+      + R W  I++ A  +L
Sbjct: 420 TENVLKEIAKAGRLFLIPATIQDKLIIRFTVTSQFTTRDDILRDWNLIRDAATLIL 475


>gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]
          Length = 594

 Score =  139 bits (351), Expect = 4e-33
 Identities = 98/363 (26%), Positives = 167/363 (46%), Gaps = 34/363 (9%)

Query: 50  PDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASP 109
           P++ E I+ D    +  GV   H P FF    T      +  + L        F++  +P
Sbjct: 162 PESLEQILVDCRDTLKYGVRTGH-PRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAP 220

Query: 110 ACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQA 169
               +E +    L KM E+    +   + +G G+     + + + +++AAR K    ++ 
Sbjct: 221 VFVLMEQIT---LKKMREI----VGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKT 273

Query: 170 ASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGV------------KLKAIPSDGNFAM 217
                   A + KLV ++S+Q+H S+++AG   G             + K IP+D     
Sbjct: 274 KG-----MAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPAD----- 323

Query: 218 RASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGS 277
                +  +   K  G +PF++ AT GTT   +FD + E+  IC K ++WLHVDAA+ G 
Sbjct: 324 ----FEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGG 379

Query: 278 AFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSH 337
             +  + RH LNG+E A+S  +NPHK + V   CSA+ VK++  L G  ++   YL    
Sbjct: 380 LLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPD 439

Query: 338 QDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPR 397
           +   +  D     I  GR     K W +++  G  G +  I K ++L+    + ++    
Sbjct: 440 KQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREE 499

Query: 398 FEI 400
           FE+
Sbjct: 500 FEM 502


>gi|197276620 glutamate decarboxylase 2 [Homo sapiens]
          Length = 585

 Score =  139 bits (349), Expect = 7e-33
 Identities = 93/357 (26%), Positives = 167/357 (46%), Gaps = 20/357 (5%)

Query: 49  EPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAAS 108
           +P   E+I+   +  +   +   H P +F    T      + AD L        F++  +
Sbjct: 152 QPQNLEEILMHCQTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIA 210

Query: 109 PACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQ 168
           P    LE V +  + +++  P        G G G+     + + + A++ AR K+     
Sbjct: 211 PVFVLLEYVTLKKMREIIGWP-------GGSGDGIFSPGGAISNMYAMMIARFKMF---- 259

Query: 169 AASPELTQA--AIMEKLVAYSSDQAHSSVERAGL---IGGVKLKAIPSDGNFAMRASALQ 223
              PE+ +   A + +L+A++S+ +H S+++      IG   +  I  D    M  S L+
Sbjct: 260 ---PEVKEKGMAALPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLE 316

Query: 224 EALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPE 283
             +   K  G +PF + AT GTT   +FD LL V  IC K  IW+HVDAA+ G   +  +
Sbjct: 317 RRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRK 376

Query: 284 FRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLI 343
            +  L+GVE A+S  +NPHK + V   CSA+ V++   +    ++  +YL    +   L 
Sbjct: 377 HKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLS 436

Query: 344 TDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEI 400
            D     +  GR     K+W ++R  G  G +A++ K ++L+    ++++    +E+
Sbjct: 437 YDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEM 493


>gi|4503875 glutamate decarboxylase 2 [Homo sapiens]
          Length = 585

 Score =  139 bits (349), Expect = 7e-33
 Identities = 93/357 (26%), Positives = 167/357 (46%), Gaps = 20/357 (5%)

Query: 49  EPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAAS 108
           +P   E+I+   +  +   +   H P +F    T      + AD L        F++  +
Sbjct: 152 QPQNLEEILMHCQTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIA 210

Query: 109 PACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQ 168
           P    LE V +  + +++  P        G G G+     + + + A++ AR K+     
Sbjct: 211 PVFVLLEYVTLKKMREIIGWP-------GGSGDGIFSPGGAISNMYAMMIARFKMF---- 259

Query: 169 AASPELTQA--AIMEKLVAYSSDQAHSSVERAGL---IGGVKLKAIPSDGNFAMRASALQ 223
              PE+ +   A + +L+A++S+ +H S+++      IG   +  I  D    M  S L+
Sbjct: 260 ---PEVKEKGMAALPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLE 316

Query: 224 EALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPE 283
             +   K  G +PF + AT GTT   +FD LL V  IC K  IW+HVDAA+ G   +  +
Sbjct: 317 RRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRK 376

Query: 284 FRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLI 343
            +  L+GVE A+S  +NPHK + V   CSA+ V++   +    ++  +YL    +   L 
Sbjct: 377 HKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLS 436

Query: 344 TDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEI 400
            D     +  GR     K+W ++R  G  G +A++ K ++L+    ++++    +E+
Sbjct: 437 YDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEM 493


>gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]
          Length = 521

 Score =  132 bits (331), Expect = 9e-31
 Identities = 93/344 (27%), Positives = 163/344 (47%), Gaps = 22/344 (6%)

Query: 74  PYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFL 133
           P FF        Y +++A  +  A+    +++  SP    +E  +   L KM+E    F+
Sbjct: 115 PRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAV---LKKMIE----FI 167

Query: 134 NEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM--EKLVAYSSDQA 191
             K  EG G+     S + + A+  AR K         P++ +  +    +L+ ++S + 
Sbjct: 168 GWK--EGDGIFNPGGSVSNMYAMNLARYKYC-------PDIKEKGLSGSPRLILFTSAEC 218

Query: 192 HSSVERAGL---IGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTC 248
           H S+++A     IG   +  + +DG   M    L++ + + +  G  PF + AT GTT  
Sbjct: 219 HYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVL 278

Query: 249 CSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVN 308
            +FD L E+  IC +  +WLHVDA++ GSA +  + R LL+G+  ADS  +NPHK L+  
Sbjct: 279 GAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAG 338

Query: 309 FDCSAMWVKKRTD-LTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFR 367
             C A+ VK ++D L   +    +YL    +   +  D     I   RR  + K W  ++
Sbjct: 339 IQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWK 398

Query: 368 MYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCF 411
             G  GL+  + + + LS      +++   F++ +E     +CF
Sbjct: 399 ALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICF 442


>gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]
          Length = 520

 Score =  118 bits (296), Expect = 1e-26
 Identities = 91/384 (23%), Positives = 170/384 (44%), Gaps = 23/384 (5%)

Query: 34  EPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADM 93
           EP  L+ L+      + ++ + I+     +I   V   H  +F   F     + A+   +
Sbjct: 75  EPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPH-ALAGRI 133

Query: 94  LCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATL 153
           +  ++    +++  +P    +E        ++L   +A +   +G+G     GS S    
Sbjct: 134 ITESLNTSQYTYEIAPVFVLMEE-------EVLRKLRALVGWSSGDGIFCPGGSISNMYA 186

Query: 154 VALLAARTKVIHRLQAASPELTQAAI--MEKLVAYSSDQAHSSVERAGLIGGV---KLKA 208
           V L   +           P+  Q  +  +  L  ++S + H S+++     G+    ++ 
Sbjct: 187 VNLARYQRY---------PDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRV 237

Query: 209 IPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWL 268
           + +D    M    L+  +   +A G +PF + AT GTT   +FD L  +  +C +  +WL
Sbjct: 238 VKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWL 297

Query: 269 HVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTD-LTGAFR 327
           HVDAA+ GS  +    RHLL+G++ ADS  +NPHK L     CSA+ ++  ++ L     
Sbjct: 298 HVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHG 357

Query: 328 LDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHE 387
              +YL    +   +  D     +  GRR   LK+W +++  G +GL+  I +   L+  
Sbjct: 358 SQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARY 417

Query: 388 FESLVRQDPRFEICVEVILGLVCF 411
               +++   FE+ +E     VCF
Sbjct: 418 LVEEMKKREGFELVMEPEFVNVCF 441


>gi|190341074 pyridoxal-dependent decarboxylase domain containing 1
           [Homo sapiens]
          Length = 788

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 47/213 (22%), Positives = 79/213 (37%), Gaps = 26/213 (12%)

Query: 217 MRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAG 276
           M  + L++ ++ D   G +P  +VA  GT      D +  +  +C +  IWLHV+     
Sbjct: 216 MDVAFLEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLA 275

Query: 277 SAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHS 336
           +  +      +L   +  DS    P  WL                        P    + 
Sbjct: 276 TLALGYVSSSVLAAAK-CDSMTMTPGPWL-------------------GLPAVPAVTLYK 315

Query: 337 HQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDP 396
           H D  L             + R+L +W   +  G+ G    I+   QLS   +  +++  
Sbjct: 316 HDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKKVN 375

Query: 397 RFEICVEVILG--LVCFR----LKGSNKVNEAL 423
             +I VE  L   +V FR    L GS+ V +A+
Sbjct: 376 YIKILVEDELSSPVVVFRFFQELPGSDPVFKAV 408


>gi|5174593 melatonin receptor 1A [Homo sapiens]
          Length = 350

 Score = 32.3 bits (72), Expect = 0.98
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 104 SWAASP-ACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALL 157
           SW AS  AC  + T+++D LG +L +   + N+K    G +   S + A LV  +
Sbjct: 24  SWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAI 78


>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
          Length = 1798

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 13/37 (35%), Positives = 22/37 (59%)

Query: 33  VEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVT 69
           V+PGY RP +     +  DT   +++ VE+++ PG T
Sbjct: 555 VQPGYFRPFLDHLIWEAEDTRGQVLDVVERLVTPGET 591


>gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]
          Length = 568

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 31/142 (21%), Positives = 55/142 (38%), Gaps = 18/142 (12%)

Query: 142 GVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLI 201
           G +    +E+ L+A  A R     +    +PE+            +   AH++  +A   
Sbjct: 204 GCVTSGGTESILMACKAYRDLAFEK-GIKTPEIV-----------APQSAHAAFNKAASY 251

Query: 202 GGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPIC 261
            G+K+  +P      +   A++ A+ R+ A       +V +         D + EV  + 
Sbjct: 252 FGMKIVRVPLTKMMEVDVRAMRRAISRNTA------MLVCSTPQFPHGVIDPVPEVAKLA 305

Query: 262 NKEDIWLHVDAAYAGSAFICPE 283
            K  I LHVDA   G   +  E
Sbjct: 306 VKYKIPLHVDACLGGFLIVFME 327


>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
          Length = 2073

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 11/94 (11%)

Query: 19  NYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFA 78
           +Y+ GI   Q+       Y++  I +     P+ F  ++  +EK++   +TH   PY   
Sbjct: 448 SYIHGIAESQLR------YIQQGIFSVTNPHPEIF--LVARIEKVLQGNITHCAEPYIKN 499

Query: 79  YFPTASSYPA-MLADMLCGAIG--CIGFSWAASP 109
             P  ++      A  +C  +G   + F+WAA P
Sbjct: 500 SDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARP 533


>gi|10190742 ubiquitin specific peptidase 29 [Homo sapiens]
          Length = 922

 Score = 29.3 bits (64), Expect = 8.3
 Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 415 GSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICS--RTVESAHVQRAWEHIK 468
           G  K+ EAL++ +   K+I LV      KF+  F + +  R+V   H ++   H++
Sbjct: 18  GMTKLKEALIETVQRQKEIKLVVTFKSGKFIRIFQLSNNIRSVVLRHCKKRQSHLR 73


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,529,382
Number of Sequences: 37866
Number of extensions: 752007
Number of successful extensions: 2017
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1999
Number of HSP's gapped (non-prelim): 16
length of query: 480
length of database: 18,247,518
effective HSP length: 106
effective length of query: 374
effective length of database: 14,233,722
effective search space: 5323412028
effective search space used: 5323412028
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.