Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4502743
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
(346 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 703 0.0
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 271 8e-73
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 266 3e-71
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 258 4e-69
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 253 2e-67
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 251 7e-67
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 243 2e-64
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 242 3e-64
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 242 3e-64
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 240 1e-63
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 240 1e-63
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 240 1e-63
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 240 1e-63
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 240 1e-63
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 240 1e-63
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 239 2e-63
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 228 5e-60
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 228 5e-60
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 225 4e-59
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 225 4e-59
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 225 4e-59
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 225 5e-59
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 221 6e-58
gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens] 211 6e-55
gi|4502747 cyclin-dependent kinase 9 [Homo sapiens] 209 4e-54
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 206 2e-53
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 206 2e-53
gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens] 205 6e-53
gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens] 204 9e-53
gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens] 204 9e-53
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 703 bits (1814), Expect = 0.0
Identities = 346/346 (100%), Positives = 346/346 (100%)
Query: 1 MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL 60
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
Sbjct: 1 MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL 60
Query: 61 REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM 120
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
Sbjct: 61 REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM 120
Query: 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA 180
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA
Sbjct: 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA 180
Query: 181 PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM 240
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
Sbjct: 181 PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM 240
Query: 241 CSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPG 300
CSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPG
Sbjct: 241 CSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPG 300
Query: 301 PTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
PTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
Sbjct: 301 PTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 271 bits (692), Expect = 8e-73
Identities = 137/297 (46%), Positives = 194/297 (65%), Gaps = 6/297 (2%)
Query: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
++K++ +GEG + VYKA+++ T Q+VA+KKI+L E G+ TA+REI LL+EL H
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEME---GVPSTAIREISLLKELKH 60
Query: 72 PNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSH-IKAYMLMTLQGLEYLHQ 130
PNI+ LLD ++ + LVF+F+ DL+ + P H IK+Y+ LQG+ + H
Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
H ++HRDLKP NLL++E G +KLADFGLA++FG P R YTH+VVT WYRAPE+L G++ Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV-TF 249
VD+W++GCI AE++ R PGDS++DQL RIF LGTP+E+ WP + LPDY +F
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
Query: 250 KSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQ 306
+ L I + DL+ L ++P RITA AL YFS+ P P+P +
Sbjct: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPSPAAR 296
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 266 bits (679), Expect = 3e-71
Identities = 134/300 (44%), Positives = 194/300 (64%), Gaps = 5/300 (1%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++K++ +GEG + VYKAR+K T ++VA+KKI+L +E G+ TA+REI LL+EL
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETE---GVPSTAIREISLLKEL 58
Query: 70 SHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSH-IKAYMLMTLQGLEYL 128
+HPNI+ LLD ++ + LVF+F+ DL+ + ++L P IK+Y+ LQGL +
Sbjct: 59 NHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
Query: 129 HQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGAR 188
H H +LHRDLKP NLL++ G +KLADFGLA++FG P R YTH+VVT WYRAPE+L G +
Sbjct: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
Query: 189 MYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY-V 247
Y VD+W++GCI AE++ R PGDS++DQL RIF TLGTP E WP + S+PDY
Sbjct: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
Query: 248 TFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQL 307
+F + + +D L+ + ++P RI+A AL +F + P P +L
Sbjct: 239 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 298
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 258 bits (660), Expect = 4e-69
Identities = 133/290 (45%), Positives = 187/290 (64%), Gaps = 5/290 (1%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
++YEKL+ +GEG + TV+KA+++ T++IVA+K+++L E G+ +ALREI LL+EL
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDE---GVPSSALREICLLKEL 58
Query: 70 SHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
H NI+ L D ++LVF+F + DL+ + L P +K+++ L+GL + H
Sbjct: 59 KHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
Query: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
+LHRDLKP NLL++ NG LKLADFGLA++FG P R Y+ +VVT WYR P++LFGA++
Sbjct: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
Query: 190 YGVGVDMWAVGCILAELL-LRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVT 248
Y +DMW+ GCI AEL P PG+ DQL RIF LGTPTEEQWP M LPDY
Sbjct: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP 238
Query: 249 FKSFPG-IPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297
+ +P L ++ DL+Q L NP RI+A +AL+ YFS+
Sbjct: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 253 bits (646), Expect = 2e-67
Identities = 130/290 (44%), Positives = 183/290 (63%), Gaps = 8/290 (2%)
Query: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Y K++ +GEG + VYK R K T Q+VA+KKI+L E G+ TA+REI LL+EL H
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEE---GVPSTAIREISLLKELRH 60
Query: 72 PNIIGLLDAFGHKSNISLVFDFMETDLEVIIKD--NSLVLTPSHIKAYMLMTLQGLEYLH 129
PNI+ L D S + L+F+F+ DL+ + + S +K+Y+ LQG+ + H
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
+LHRDLKP NLL+D+ G +KLADFGLA++FG P R YTH+VVT WYR+PE+L G+
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 190 YGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV-T 248
Y VD+W++G I AEL + P GDS++DQL RIF LGTP E WP++ SL DY T
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 249 FKSF-PGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297
F + PG H+ ++ LDL+ + +++P RI+ AL YF++
Sbjct: 241 FPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 251 bits (641), Expect = 7e-67
Identities = 128/290 (44%), Positives = 182/290 (62%), Gaps = 8/290 (2%)
Query: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Y K++ +GEG + VYK R K T Q+VA+KKI+L E G+ TA+REI LL+EL H
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEE---GVPSTAIREISLLKELRH 60
Query: 72 PNIIGLLDAFGHKSNISLVFDFMETDLEVIIKD--NSLVLTPSHIKAYMLMTLQGLEYLH 129
PNI+ L D S + L+F+F+ DL+ + + S +K+Y+ LQG+ + H
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189
+LHRDLKP NLL+D+ G +KLADFGLA++FG P R YTH+ +T WYR+PE+L G+
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
Query: 190 YGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV-T 248
Y VD+W++G I AEL + P GDS++DQL RIF LGTP E WP++ SL DY T
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 249 FKSF-PGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297
F + PG H+ ++ LDL+ + +++P RI+ AL YF++
Sbjct: 241 FPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 243 bits (619), Expect = 2e-64
Identities = 130/304 (42%), Positives = 182/304 (59%), Gaps = 7/304 (2%)
Query: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
+Y L +GEG V+KA+ T +IVA+KK+ L +DG ALREIK LQE+
Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETGEIVALKKVAL---RRLEDGFPNQALREIKALQEME 59
Query: 71 -HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
+ ++ L F H L F+FM +DL +++ L + +K+Y+ M L+G+ + H
Sbjct: 60 DNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCH 119
Query: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSP-NRAYTHQVVTRWYRAPELLFGAR 188
+ I+HRDLKP NLL+ +G LK+ADFGLA+ F +R YTHQV TRWYRAPELL+GAR
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
Query: 189 MYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY-- 246
Y GVD+W+VGCI+ ELL P PG +D++QL + LGTP + WP++ LPDY
Sbjct: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
Query: 247 VTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQ 306
++FK +PL + LDL+ L+ P RI A++AL +YF P P +
Sbjct: 240 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSE 299
Query: 307 LPRP 310
LP P
Sbjct: 300 LPIP 303
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 242 bits (618), Expect = 3e-64
Identities = 130/336 (38%), Positives = 200/336 (59%), Gaps = 16/336 (4%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 411 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 467
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 468 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 527
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT+WYRAPELL GA
Sbjct: 528 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 587
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+ Y VDMW+VGCI ELL + P PG+S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 588 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 647
Query: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 648 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 707
Query: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
P P ++ +++ +KR + +GGL
Sbjct: 708 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 735
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 242 bits (618), Expect = 3e-64
Identities = 130/336 (38%), Positives = 200/336 (59%), Gaps = 16/336 (4%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 477
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 478 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 537
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT+WYRAPELL GA
Sbjct: 538 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 597
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+ Y VDMW+VGCI ELL + P PG+S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 598 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 657
Query: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 658 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 717
Query: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
P P ++ +++ +KR + +GGL
Sbjct: 718 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 745
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 240 bits (613), Expect = 1e-63
Identities = 130/336 (38%), Positives = 198/336 (58%), Gaps = 16/336 (4%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 412 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 468
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 469 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 528
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT WYRAPELL GA
Sbjct: 529 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 588
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+ Y VDMW+VGCI ELL + P PG S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 589 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 648
Query: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 649 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 708
Query: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
P P ++ +++ +KR + +GGL
Sbjct: 709 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 736
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 240 bits (613), Expect = 1e-63
Identities = 130/336 (38%), Positives = 198/336 (58%), Gaps = 16/336 (4%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 477
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 478 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 537
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT WYRAPELL GA
Sbjct: 538 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 597
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+ Y VDMW+VGCI ELL + P PG S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 598 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 657
Query: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 658 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 717
Query: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
P P ++ +++ +KR + +GGL
Sbjct: 718 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 745
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 240 bits (613), Expect = 1e-63
Identities = 130/336 (38%), Positives = 198/336 (58%), Gaps = 16/336 (4%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 389 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 445
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 446 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 505
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT WYRAPELL GA
Sbjct: 506 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 565
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+ Y VDMW+VGCI ELL + P PG S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 566 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 625
Query: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 626 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 685
Query: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
P P ++ +++ +KR + +GGL
Sbjct: 686 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 713
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 240 bits (613), Expect = 1e-63
Identities = 130/336 (38%), Positives = 198/336 (58%), Gaps = 16/336 (4%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 378 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 434
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 435 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 494
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT WYRAPELL GA
Sbjct: 495 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 554
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+ Y VDMW+VGCI ELL + P PG S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 555 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 614
Query: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 615 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 674
Query: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
P P ++ +++ +KR + +GGL
Sbjct: 675 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 702
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 240 bits (613), Expect = 1e-63
Identities = 130/336 (38%), Positives = 198/336 (58%), Gaps = 16/336 (4%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 167 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 223
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 224 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 283
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT WYRAPELL GA
Sbjct: 284 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 343
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+ Y VDMW+VGCI ELL + P PG S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 344 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 403
Query: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 404 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 463
Query: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
P P ++ +++ +KR + +GGL
Sbjct: 464 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 491
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 240 bits (613), Expect = 1e-63
Identities = 130/336 (38%), Positives = 198/336 (58%), Gaps = 16/336 (4%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
+ ++ L+ + EG + VY+A+DK T++IVA+K++K+ + K+G T+LREI + +
Sbjct: 423 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM---EKEKEGFPITSLREINTILKA 479
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ + + + I +V +++E DL+ +++ P +K M+ L+G+++
Sbjct: 480 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH 539
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH +WILHRDLK +NLLL G+LK+ DFGLA+ +GSP +AYT VVT WYRAPELL GA
Sbjct: 540 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 599
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+ Y VDMW+VGCI ELL + P PG S++DQ+ ++F+ LGTP+E+ WP LP
Sbjct: 600 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 659
Query: 246 YVTFKSFPGIPLHHIFSA-AGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPG 304
+TF P L F A D DL+ + P RI+A LK +YF P P
Sbjct: 660 KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP 719
Query: 305 CQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGL 340
P P ++ +++ +KR + +GGL
Sbjct: 720 SMF--PTWPAKSEQQR------VKRGTSPRPPEGGL 747
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 239 bits (611), Expect = 2e-63
Identities = 127/296 (42%), Positives = 183/296 (61%), Gaps = 7/296 (2%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
K +EKL+ +GEG + VY+ARD T++IVA+KK+++ + KDGI ++LREI LL L
Sbjct: 37 KEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRM---DKEKDGIPISSLREITLLLRL 93
Query: 70 SHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
HPNI+ L + H +I LV + E DL ++++ + + +K +L L+GL+Y
Sbjct: 94 RHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQY 153
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
LH+++I+HRDLK +NLL+ + G +K ADFGLA+++G P + T +VVT WYRAPELL G
Sbjct: 154 LHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGT 213
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP--D 245
+DMWAVGCILAELL P LPG S++ Q+ I + LGTP+E WP LP
Sbjct: 214 TTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVG 273
Query: 246 YVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGP 301
+ + P L H F + L L+ LF+++P R TA L+ YF +P P
Sbjct: 274 QYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLP 329
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 228 bits (582), Expect = 5e-60
Identities = 119/291 (40%), Positives = 180/291 (61%), Gaps = 8/291 (2%)
Query: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
+ + Y KLD LGEG +ATVYK + K T+ +VA+K+I+L H ++G TA+RE+ LL+
Sbjct: 167 KLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEH----EEGAPCTAIREVSLLK 222
Query: 68 ELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
+L H NI+ L D + +++LVF++++ DL+ + D ++ ++K ++ L+GL Y
Sbjct: 223 DLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAY 282
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
H+ +LHRDLKP NLL++E G LKLADFGLA++ P + Y+++VVT WYR P++L G+
Sbjct: 283 CHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGS 342
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV 247
Y +DMW VGCI E+ P PG + +QL IF LGTPTEE WP + S ++
Sbjct: 343 TDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFK 402
Query: 248 TFKSFPGIPLHHIFSAA---GDDLLDLIQGLFLFNPCARITATQALKMKYF 295
T+ ++P + S A D DL+ L F RI+A A+K +F
Sbjct: 403 TY-NYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 452
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 228 bits (582), Expect = 5e-60
Identities = 119/291 (40%), Positives = 180/291 (61%), Gaps = 8/291 (2%)
Query: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
+ + Y KLD LGEG +ATVYK + K T+ +VA+K+I+L H ++G TA+RE+ LL+
Sbjct: 161 KLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEH----EEGAPCTAIREVSLLK 216
Query: 68 ELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
+L H NI+ L D + +++LVF++++ DL+ + D ++ ++K ++ L+GL Y
Sbjct: 217 DLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAY 276
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
H+ +LHRDLKP NLL++E G LKLADFGLA++ P + Y+++VVT WYR P++L G+
Sbjct: 277 CHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGS 336
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV 247
Y +DMW VGCI E+ P PG + +QL IF LGTPTEE WP + S ++
Sbjct: 337 TDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFK 396
Query: 248 TFKSFPGIPLHHIFSAA---GDDLLDLIQGLFLFNPCARITATQALKMKYF 295
T+ ++P + S A D DL+ L F RI+A A+K +F
Sbjct: 397 TY-NYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 446
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 225 bits (574), Expect = 4e-59
Identities = 119/291 (40%), Positives = 178/291 (61%), Gaps = 8/291 (2%)
Query: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
+ + Y KLD LGEG +ATV+K R K T +VA+K+I+L H ++G TA+RE+ LL+
Sbjct: 170 KLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEH----EEGAPCTAIREVSLLK 225
Query: 68 ELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
L H NI+ L D +++LVF+++++DL+ + +++ ++K +M L+GL Y
Sbjct: 226 NLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAY 285
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
H ILHRDLKP NLL++E G LKLADFGLA++ P + Y+++VVT WYR P++L G+
Sbjct: 286 CHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGS 345
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV 247
Y +DMW VGCI E+ P PG + ++L IF LGTPTEE WP + + ++
Sbjct: 346 TEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFR 405
Query: 248 TFKSFPGI---PLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYF 295
T+ SFP PL + D + L+ L L+ +R++A AL YF
Sbjct: 406 TY-SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 455
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 225 bits (574), Expect = 4e-59
Identities = 119/291 (40%), Positives = 178/291 (61%), Gaps = 8/291 (2%)
Query: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
+ + Y KLD LGEG +ATV+K R K T +VA+K+I+L H ++G TA+RE+ LL+
Sbjct: 140 KLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEH----EEGAPCTAIREVSLLK 195
Query: 68 ELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
L H NI+ L D +++LVF+++++DL+ + +++ ++K +M L+GL Y
Sbjct: 196 NLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAY 255
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
H ILHRDLKP NLL++E G LKLADFGLA++ P + Y+++VVT WYR P++L G+
Sbjct: 256 CHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGS 315
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV 247
Y +DMW VGCI E+ P PG + ++L IF LGTPTEE WP + + ++
Sbjct: 316 TEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFR 375
Query: 248 TFKSFPGI---PLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYF 295
T+ SFP PL + D + L+ L L+ +R++A AL YF
Sbjct: 376 TY-SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 425
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 225 bits (574), Expect = 4e-59
Identities = 119/291 (40%), Positives = 178/291 (61%), Gaps = 8/291 (2%)
Query: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
+ + Y KLD LGEG +ATV+K R K T +VA+K+I+L H ++G TA+RE+ LL+
Sbjct: 140 KLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEH----EEGAPCTAIREVSLLK 195
Query: 68 ELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
L H NI+ L D +++LVF+++++DL+ + +++ ++K +M L+GL Y
Sbjct: 196 NLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAY 255
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
H ILHRDLKP NLL++E G LKLADFGLA++ P + Y+++VVT WYR P++L G+
Sbjct: 256 CHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGS 315
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV 247
Y +DMW VGCI E+ P PG + ++L IF LGTPTEE WP + + ++
Sbjct: 316 TEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFR 375
Query: 248 TFKSFPGI---PLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYF 295
T+ SFP PL + D + L+ L L+ +R++A AL YF
Sbjct: 376 TY-SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 425
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 225 bits (573), Expect = 5e-59
Identities = 124/297 (41%), Positives = 179/297 (60%), Gaps = 9/297 (3%)
Query: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
+A YEKL+ LGEG +ATVYK + K ++VA+K I+L + ++G TA+RE LL+
Sbjct: 113 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL----QEEEGTPFTAIREASLLK 168
Query: 68 ELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
L H NI+ L D K ++LVF+++ TDL + + L P ++K ++ L+GL Y
Sbjct: 169 GLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSY 228
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
+HQ +ILHRDLKP NLL+ + G LKLADFGLA++ P+ Y+++VVT WYR P++L G+
Sbjct: 229 IHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGS 288
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDL-DQLTRIFETLGTPTEEQWPDMCSLPDY 246
Y +DMW VGCI E++ V PG D+ DQL RIF LGTP E+ WP + SLP +
Sbjct: 289 TEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHF 348
Query: 247 --VTFKSFPGIPLHHIFSAAG--DDLLDLIQGLFLFNPCARITATQALKMKYFSNRP 299
F + L ++ + DL L +P R++A AL +YFS+ P
Sbjct: 349 KPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 405
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 221 bits (564), Expect = 6e-58
Identities = 113/290 (38%), Positives = 177/290 (61%), Gaps = 6/290 (2%)
Query: 8 RAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
+ + Y KL+ LGEG +ATVYK R K T +VA+K+I+L H ++G TA+RE+ LL+
Sbjct: 188 KMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEH----EEGAPCTAIREVSLLK 243
Query: 68 ELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
+L H NI+ L D +++LVF++++ DL+ + D +++ ++K ++ L+GL Y
Sbjct: 244 DLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAY 303
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
H+ +LHRDLKP NLL++E G LKLADFGLA++ P + Y+++VVT WYR P++L G+
Sbjct: 304 CHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGS 363
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY- 246
Y +DMW VGCI E+ P PG + D+L IF LGTP++E WP + S ++
Sbjct: 364 SEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFK 423
Query: 247 -VTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYF 295
F + PL + + ++LI + R++A +A+K YF
Sbjct: 424 NYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF 473
>gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens]
Length = 384
Score = 211 bits (538), Expect = 6e-55
Identities = 121/298 (40%), Positives = 174/298 (58%), Gaps = 13/298 (4%)
Query: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQE 68
A Y L+ LGEG +ATVYK + Q+VA+K I + A++G+ TA+RE LL+
Sbjct: 49 ASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMN----AEEGVPFTAIREASLLKG 104
Query: 69 LSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYL 128
L H NI+ L D K ++ VF++M TDL + + L P +++ +M L+GL Y+
Sbjct: 105 LKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYI 164
Query: 129 HQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGAR 188
H +LHRDLKP NLL+ G LKLADFGLA++ P++ Y+ +VVT WYR P+ L GA
Sbjct: 165 HHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGAT 224
Query: 189 MYGVGVDMWAVGCILAELLLRVPFLPGDSD-LDQLTRIFETLGTPTEEQWPDMCSLPDYV 247
Y +D+W GCI E+ P PG S+ L+QL +I+E LG PTE+ WP + LP+Y
Sbjct: 225 EYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNY- 283
Query: 248 TFKSFPGIP----LHHIFSAAG--DDLLDLIQGLFLFNPCARITATQALKMKYFSNRP 299
+ FP +P LH +++ G + DL + P R++A +AL YFS P
Sbjct: 284 NPEWFP-LPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALP 340
>gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]
Length = 372
Score = 209 bits (531), Expect = 4e-54
Identities = 127/309 (41%), Positives = 180/309 (58%), Gaps = 21/309 (6%)
Query: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
+YEKL +G+G F V+KAR + T Q VA+KK+ + + K+G TALREIK+LQ L
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENE---KEGFPITALREIKILQLLK 74
Query: 71 HPNIIGLLDAFGHKSN--------ISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTL 122
H N++ L++ K++ I LVFDF E DL ++ + + T S IK M M L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 123 QGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSF-----GSPNRAYTHQVVTRW 177
GL Y+H++ ILHRD+K N+L+ +GVLKLADFGLA++F PNR YT++VVT W
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNR-YTNRVVTLW 193
Query: 178 YRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQW 237
YR PELL G R YG +D+W GCI+AE+ R P + G+++ QL I + G+ T E W
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVW 253
Query: 238 PDMCSLPDYVTFKSFPG--IPLHHIFSAAGDD--LLDLIQGLFLFNPCARITATQALKMK 293
P++ + Y + G + A D LDLI L + +P RI + AL
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 294 YFSNRPGPT 302
+F + P P+
Sbjct: 314 FFWSDPMPS 322
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 206 bits (524), Expect = 2e-53
Identities = 116/312 (37%), Positives = 177/312 (56%), Gaps = 17/312 (5%)
Query: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
+++ + +GEG + VYKARDK+T ++VA+KK++L + K+G TA+REIK+L++L+
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNE---KEGFPITAIREIKILRQLT 760
Query: 71 HPNIIGL----------LDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM 120
H +II + LD K LVF++M+ DL +++ + +HIK++M
Sbjct: 761 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQ 820
Query: 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSP-NRAYTHQVVTRWYR 179
++GL+Y H+ LHRD+K +N+LL+ G +KLADFGLA+ + S +R YT++V+T WYR
Sbjct: 821 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPD 239
PELL G Y +D+W+ GCIL EL + P + +L QL I G+P WPD
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 240 MCSLPDYVTFKSFPGI--PLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297
+ LP + T K L F LDL + +P R TA QAL+ ++ +
Sbjct: 941 VIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
Query: 298 -RPGPTPGCQLP 308
P P LP
Sbjct: 1001 VEPSKMPPPDLP 1012
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 206 bits (524), Expect = 2e-53
Identities = 116/312 (37%), Positives = 177/312 (56%), Gaps = 17/312 (5%)
Query: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
+++ + +GEG + VYKARDK+T ++VA+KK++L + K+G TA+REIK+L++L+
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNE---KEGFPITAIREIKILRQLT 760
Query: 71 HPNIIGL----------LDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM 120
H +II + LD K LVF++M+ DL +++ + +HIK++M
Sbjct: 761 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQ 820
Query: 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSP-NRAYTHQVVTRWYR 179
++GL+Y H+ LHRD+K +N+LL+ G +KLADFGLA+ + S +R YT++V+T WYR
Sbjct: 821 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 180 APELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPD 239
PELL G Y +D+W+ GCIL EL + P + +L QL I G+P WPD
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 240 MCSLPDYVTFKSFPGI--PLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297
+ LP + T K L F LDL + +P R TA QAL+ ++ +
Sbjct: 941 VIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
Query: 298 -RPGPTPGCQLP 308
P P LP
Sbjct: 1001 VEPSKMPPPDLP 1012
>gi|237858575 cyclin-dependent kinase 10 isoform b [Homo sapiens]
Length = 272
Score = 205 bits (521), Expect = 6e-53
Identities = 112/267 (41%), Positives = 157/267 (58%), Gaps = 10/267 (3%)
Query: 52 KDGINRTALREIKLLQELSHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVL 109
KDGI ++LREI LL L HPNI+ L + H +I LV + E DL ++++
Sbjct: 5 KDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPF 64
Query: 110 TPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAY 169
+ + +K +L L+GL+YLH+++I+HRDLK +NLL+ + G +K ADFGLA+++G P +
Sbjct: 65 SEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM 124
Query: 170 THQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETL 229
T +VVT WYRAPELL G +DMWAVGCILAELL P LPG S++ Q+ I + L
Sbjct: 125 TPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLL 184
Query: 230 GTPTEEQWPDMCSLP--DYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITAT 287
GTP+E WP LP + + P L H F + L L+ LF+++P R TA
Sbjct: 185 GTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAG 244
Query: 288 QALKMKYFSNRP------GPTPGCQLP 308
L+ YF +P G GC+ P
Sbjct: 245 DCLESSYFKEKPLRLPISGVCEGCREP 271
>gi|237858582 cyclin-dependent kinase 10 isoform d [Homo sapiens]
Length = 289
Score = 204 bits (519), Expect = 9e-53
Identities = 109/254 (42%), Positives = 153/254 (60%), Gaps = 4/254 (1%)
Query: 52 KDGINRTALREIKLLQELSHPNIIGLLDAF--GHKSNISLVFDFMETDLEVIIKDNSLVL 109
KDGI ++LREI LL L HPNI+ L + H +I LV + E DL ++++
Sbjct: 5 KDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPF 64
Query: 110 TPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAY 169
+ + +K +L L+GL+YLH+++I+HRDLK +NLL+ + G +K ADFGLA+++G P +
Sbjct: 65 SEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM 124
Query: 170 THQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETL 229
T +VVT WYRAPELL G +DMWAVGCILAELL P LPG S++ Q+ I + L
Sbjct: 125 TPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLL 184
Query: 230 GTPTEEQWPDMCSLP--DYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITAT 287
GTP+E WP LP + + P L H F + L L+ LF+++P R TA
Sbjct: 185 GTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAG 244
Query: 288 QALKMKYFSNRPGP 301
L+ YF +P P
Sbjct: 245 DCLESSYFKEKPLP 258
>gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens]
Length = 358
Score = 204 bits (519), Expect = 9e-53
Identities = 120/296 (40%), Positives = 170/296 (57%), Gaps = 16/296 (5%)
Query: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
++YEK+ +GEG + V+K R+++T QIVAIKK SE I + ALREI++L++L
Sbjct: 3 EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFL---ESEDDPVIKKIALREIRMLKQL 59
Query: 70 SHPNIIGLLDAFGHKSNISLVFDFME-TDLEVIIKDNSLVLTPSH-IKAYMLMTLQGLEY 127
HPN++ LL+ F K + LVF++ + T L + + V P H +K+ TLQ + +
Sbjct: 60 KHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGV--PEHLVKSITWQTLQAVNF 117
Query: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
H+H +HRD+KP N+L+ ++ V+KL DFG A+ P+ YT V TRWYR+PELL G
Sbjct: 118 CHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGD 177
Query: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLG--TPTEEQWPDMCSLPD 245
YG VD+WA+GC+ AELL VP PG SD+DQL I +TLG P +Q + S
Sbjct: 178 TQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQ---VFSTNQ 234
Query: 246 YVTFKSFPG----IPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297
Y + P PL F L L++G +P R+T Q L YF N
Sbjct: 235 YFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,597,624
Number of Sequences: 37866
Number of extensions: 646886
Number of successful extensions: 3755
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 734
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 1453
Number of HSP's gapped (non-prelim): 946
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.